CN203419926U - Biological test device for high magnetic field - Google Patents
Biological test device for high magnetic field Download PDFInfo
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- CN203419926U CN203419926U CN201320194753.1U CN201320194753U CN203419926U CN 203419926 U CN203419926 U CN 203419926U CN 201320194753 U CN201320194753 U CN 201320194753U CN 203419926 U CN203419926 U CN 203419926U
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Abstract
The utility model discloses a biological test device for a high magnetic field. The biological test device comprises a sample cavity and a master control module, wherein a constant-temperature water liner and a sample tray are arranged in the sample cavity; an illumination optical fiber extends out of the upper end of the sample cavity, and a CCD (charge coupled device) camera is fixed in the middle of the illumination optical fiber and located above the sample tray; a temperature sensor is further arranged in the sample cavity, a signal output end of the temperature sensor is led out from a small hole in the side wall of the sample cavity through a temperature lead, a gas feeding inlet and a gas outlet are formed in the side wall of the sample cavity, and the upper end and the lower end of the sample cavity are sealed; and the master control module is connected with the temperature lead, the CCD camera, a gas control device and a data display device, and the gas control device controls an electromagnetic valve for connecting the gas feeding inlet and the gas outlet. The biological test device is convenient to mount; requirements of different cell culture dishes can be met by changing the size of the sample cavity; the operation is simple, and the maintaining is convenient; and the temperature control operation of the constant-temperature water liner is convenient, the temperature control time of the sample cavity can be shortened greatly, and the test efficiency is improved.
Description
Technical field
The utility model relates to biological assay devices field, is specifically related to a kind of high-magnetic-field biological device of applicable radiation biological effect research.
Background technology
Along with deepening continuously of radiation biological effect research, people to its research range also in continuous extension, so that preferred view index and judgement criteria seem is very important.From existing investigation and result of study, magnetic biological effect is very complicated, not only relate to the kind of biology (cell), also relate to magnetic field itself and with the interaction of other environmental factors, magnetic field never has accurate and unified conclusion to the mechanism of action of organism.The superconductor occurring from the 1970s and 1980s in last century has promoted the application of high-intensity magnetic field in medical physical diagnosis and bio-science research, utility model for magnetic resonance imager (MRI) and magnetic resonant wave spectrometer and the nuclear magnetic resonance analyser for studying of medical diagnosis, according to estimates, in global range, carried out the MRI scan of about 200,000,000 times.From cell and molecular level, inquire into magnetic field and the interactional mechanism of organism, will remain the main direction of studying in biomagnetism field.This patent high-magnetic-field biological device, designs and is suitable for seed and cell sterile culture etc. and tests to whole level magnetic field radiation from molecule, cell, tissue, organ, to meet the operation of test and the demand environment of cell normal growth.
Along with the development of high-intensity magnetic field application, magneticstrength is constantly designed and develops higher than pulsed magnetic field and the steady magnetic field of 10 T, and current high field intensity has reached 45 T.Therefore upfield is a problem can not be ignored on the impact of HUMAN HEALTH.But whether upfield exists and threatens the mankind's health, there is no at present final conclusion.The test-results of various vivo and vitros also exists much inconsistent, and the mechanism of biological effect of magnetic field is also never illustrated completely.The impact of high field intensity on seed and cell, the research of electromagnetic radiation to cytobiology effect, this will be for further its high-field effect of research and mechanism of action thereof provide experimental foundation.In addition, result of study prompting will be focused on the research of electromagnetic radiation ultimate effect far away, to guarantee the Integrity And Reliability of result of study, for biological study provides a kind of new approaches.
Utility model content
The purpose of this utility model is to provide a kind of high-magnetic-field biological device of applicable radiation biological effect research, can realize accurate measurement and the control of the overall targets such as temperature, humidity, sample position, gravity horizontal, magneticstrength, can meet from molecule, cell, tissue, organ and to whole level, carry out the simulated experiment condition needs of space life science research.
The technical solution adopted in the utility model is:
High-magnetic-field biological device, it is characterized in that: include sample cavity, the mid-persevering warm water liner of sample cavity, sample tray, deeply there is lighting fiber the upper end of sample cavity, the middle part of lighting fiber is fixed with CCD camera, CCD camera is positioned at the top of sample tray, in sample cavity, be also provided with temperature sensor, the signal output part of temperature sensor is gone between and is drawn from the aperture of sample cavity sidewall by temperature, on the sidewall of sample cavity, be also provided with gas and pass into mouth, pneumatic outlet, sample cavity upper, lower sealed at both ends, also include main control module, main control module is connected with temperature lead-in wire, CCD camera, gas control equipment, data presentation device, gas control equipment control linkage gas passes into mouth, the magnetic valve of pneumatic outlet.
Described high-magnetic-field biological device, is characterized in that: described sample cavity is cylindrical copper.
Described high-magnetic-field biological device, is characterized in that: described thermostat(t)ed water courage adopts electrobath water tank that can pressure charged temperature control, includes water tank, electrical heating wire, water-in, water outlet.
Described high-magnetic-field biological device, is characterized in that: it is 5% CO that described gas passes into mouthful gas passing into
2with 95% air gas mixture.
During use, Tissue Culture Dish is placed in to the sample tray in copper cylindrical sample chamber, by thermostat(t)ed water courage, can makes the temperature of sample cavity maintain 37.0 ± 0.2 ° of C.
The beneficial effects of the utility model are:
(1) the utility model is easy for installation, by changing sample cavity size, can meet different Tissue Culture Dishs, simple to operate, is convenient to safeguard, thermostat(t)ed water courage temperature control is easy to operate, can greatly shorten the sample cavity temperature control time, improves test efficiency.
(2) device that the utility model provides can be realized accurate measurement and the control of the overall targets such as temperature, humidity, sample position, gravity horizontal, magneticstrength, can meet from molecule, cell, tissue, organ and to whole level, carry out the simulated experiment condition needs of space life science research.
(3) in use procedure, the utility model replaces common biological test sample frame, through too much wheel test, this biological assay devices is to cell cultures and magnetic field radiation, and flexible operation, is easy to temperature control, pick and place sample more convenient, meet cell cultures and the requirement of magnetic field radiation testing experiment completely.
Accompanying drawing explanation
The structural representation of Fig. 1 thermostat(t)ed water courage of the present utility model.
Fig. 2 is structural representation of the present utility model.
Fig. 3 is control block diagram of the present utility model.
Embodiment
As Fig. 1, shown in 2, high-magnetic-field biological device, include sample cavity 1, the mid-persevering warm water liner 2 of sample cavity 1, sample tray 3, deeply there is lighting fiber 4 upper end of sample cavity 1, the middle part of lighting fiber 4 is fixed with CCD camera 5, CCD camera 5 is positioned at the top of sample tray 3, in sample cavity 1, be also provided with temperature sensor 6, the signal output part of temperature sensor 6 is gone between and is drawn from the aperture of sample cavity 1 sidewall by temperature, on the sidewall of sample cavity 1, be also provided with gas and pass into mouth 7, pneumatic outlet 8, sample cavity 1 upper, lower sealed at both ends, also include main control module 9, main control module 9 is connected with temperature lead-in wire, CCD camera 5, gas control equipment 10, data presentation device 11, gas control equipment 10 control linkage gases pass into mouth 7, the magnetic valve of pneumatic outlet 8.
Thermostat(t)ed water courage 2 adopts electrobath water tank that can pressure charged temperature control, includes water tank 12, electrical heating wire 13, water-in 14, water outlet 15.
It is 5% CO that gas passes into mouthful 7 gases that pass into
2with 95% air gas mixture.
The device that carries out space gravitational biology simulated experiment for large strong magnetic field gradient
Superconducting magnet is fixed on level ground, and control warm water liner vertically inserts in the cylindrical sample chamber in the middle of superconducting magnet.Loading lifting device base is positioned at the bottom of superconducting magnet, and the sample tray of loading lifting device inserts in the superconducting magnet sample cavity with control warm water liner.Parameter monitor device is arranged on the bottom of loading lifting device pallet.Loading lifting device is connected on data presentation device by wire.The upper and lower two ends of sample cavity of superconducting magnet are sealed by the sealing plug of gas control equipment respectively.CCD camera is positioned at ring-shaped lighting fiber optic hub, and the two synchronously stretches in cavity, is placed in pallet top.
Claims (3)
1. high-magnetic-field biological device, it is characterized in that: include sample cavity, the mid-persevering warm water liner of sample cavity, sample tray, deeply there is lighting fiber the upper end of sample cavity, the middle part of lighting fiber is fixed with CCD camera, CCD camera is positioned at the top of sample tray, in sample cavity, be also provided with temperature sensor, the signal output part of temperature sensor is gone between and is drawn from the aperture of sample cavity sidewall by temperature, on the sidewall of sample cavity, be also provided with gas and pass into mouth, pneumatic outlet, sample cavity upper, lower sealed at both ends, also include main control module, main control module is connected with temperature lead-in wire, CCD camera, gas control equipment, data presentation device, gas control equipment control linkage gas passes into mouth, the magnetic valve of pneumatic outlet.
2. high-magnetic-field biological device according to claim 1, is characterized in that: described sample cavity is cylindrical copper.
3. high-magnetic-field biological device according to claim 1, is characterized in that: described thermostat(t)ed water courage adopts electrobath water tank that can pressure charged temperature control, includes water tank, electrical heating wire, water-in, water outlet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320194753.1U CN203419926U (en) | 2013-04-17 | 2013-04-17 | Biological test device for high magnetic field |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320194753.1U CN203419926U (en) | 2013-04-17 | 2013-04-17 | Biological test device for high magnetic field |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203419926U true CN203419926U (en) | 2014-02-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320194753.1U Expired - Lifetime CN203419926U (en) | 2013-04-17 | 2013-04-17 | Biological test device for high magnetic field |
Country Status (1)
| Country | Link |
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| CN (1) | CN203419926U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103756899A (en) * | 2014-02-18 | 2014-04-30 | 中国科学院合肥物质科学研究院 | Biological continuous culturing and microscopic imaging device for steady-state high-intensity magnetic field effect researches |
| CN111304085A (en) * | 2020-03-31 | 2020-06-19 | 中国科学院合肥物质科学研究院 | Biological sample culture device suitable for static magnetic field environment and application thereof |
-
2013
- 2013-04-17 CN CN201320194753.1U patent/CN203419926U/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103756899A (en) * | 2014-02-18 | 2014-04-30 | 中国科学院合肥物质科学研究院 | Biological continuous culturing and microscopic imaging device for steady-state high-intensity magnetic field effect researches |
| CN103756899B (en) * | 2014-02-18 | 2016-03-09 | 中国科学院合肥物质科学研究院 | Can be used for biological cultured continuously and the microscopic imaging device of stable state high-intensity magnetic field effect study |
| CN111304085A (en) * | 2020-03-31 | 2020-06-19 | 中国科学院合肥物质科学研究院 | Biological sample culture device suitable for static magnetic field environment and application thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20140205 |
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| CX01 | Expiry of patent term |