CN203396201U - Heat-conducting cushion and plasma instant freezer using same - Google Patents
Heat-conducting cushion and plasma instant freezer using same Download PDFInfo
- Publication number
- CN203396201U CN203396201U CN201320373810.2U CN201320373810U CN203396201U CN 203396201 U CN203396201 U CN 203396201U CN 201320373810 U CN201320373810 U CN 201320373810U CN 203396201 U CN203396201 U CN 203396201U
- Authority
- CN
- China
- Prior art keywords
- cushion
- heat conduction
- plasma
- cold drawing
- heat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn - After Issue
Links
Images
Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The utility model relates to a heat-conducting cushion and a plasma instant freezer using the same. The heat-conducting cushion (5) comprises an upper-layer membrane (11) and a lower-layer membrane (13); a middle cavity (12) is arranged between the upper-layer membrane and the lower-layer membrane and is filled with a pre-quantified amount of refrigerant; the upper-layer membrane and the lower-layer membrane are sealed by adopting a heat seal technology. The plasma instant freezer adopting the heat-conducting cushion can ensure that each plasma bag is stressed evenly, so as to avoid the deformation or breakage of the plasma bag in an instant freezing process, realizes good temperature conductivity performance and heat conduction efficiency, and can ensure that the plasma bags of the same one batch are fast and evenly instantly frozen with a good instant freezing effect.
Description
Technical field
The utility model relates to medical instruments field, the blood plasma quick freezer that relates in particular to a kind of heat conduction cushion and use this cushion.
Background technology
In medical field, blood plasma need to carry out quick-frozen when storing, thereby need to process blood plasma with blood plasma quick freezer.At present, the blood plasma quick freezer of selling on market, what mostly adopt is air-cooled refrigerator-freezer, and plasma bags is suspended on and in refrigerator-freezer, carries out quick-frozen.The quick-frozen standard of GB GB18469-2012.3.29 is: blood plasma product will be reduced to the DIE Temperature of blood plasma below-30 ℃ in the process of snap frozen in 1 hour, yet use under normal conditions existing blood plasma quick freezer that plasma quick freezing is approximately needed to 2 hours to-30 ℃, and cannot confirm whether the DIE Temperature of plasma bags reaches-30 ℃.
Existing flat blood plasma quick freezer, it is a kind of direct-cooling type blood plasma quick freezer that adopts direct contact, generally include refrigeration unit and sweat cooling plate, refrigeration unit is connected with sweat cooling plate by copper pipe and flexible pipe, sweat cooling plate comprises evaporation cold drawing and lower evaporation cold drawing (below, respectively referred to as upper cold drawing and lower cold drawing), after putting plasma bags during use on lower cold drawing, add and cover cold drawing, by upper and lower cold drawing to plasma bags clamping pressurization so that plasma bags keeps contacting fully to carry out quick-frozen with upper and lower cold drawing, owing to manually putting, cannot guarantee evenly neatly to put, and the variable thickness of plasma bags, after may causing quick-frozen, plasma bags is out of shape, and the risk that has pressurized to break.Be subject to the restriction of upper and lower cold drawing surface processing technique, the cold drawing surface of selling on Vehicles Collected from Market cannot guarantee completely smooth, often occur plasma bags when quick-frozen with the inconsistent situation of contact area of upper cold drawing, cannot guarantee that the quick-frozen effect of each plasma bags in same time reaches consistent.
Utility model content
Main purpose of the present utility model is the blood plasma quick freezer that a kind of heat conduction cushion is provided and uses this cushion, with solve that prior art exists due to pressurized cause plasma bags distortion or break, in same time, whether the refrigerating effect of each plasma bags DIE Temperature inconsistent, that cannot confirm plasma bags can reach the problems such as predetermined temperature, wherein:
One side of the present utility model, provides a kind of conduction of the heat for blood plasma quick freezer cushion.This heat conduction cushion comprises: upper layer film and lower membrane; Between described upper layer film and lower membrane, there is intermediate cavity, in described intermediate cavity, be filled with the refrigerant of scheduled volume; Described upper layer film and lower membrane seal through hot sealing process.
In addition, in described heat conduction cushion, described upper layer film and lower membrane adopt resin material; Described refrigerant comprises refrigerating liquid.
In addition, in described heat conduction cushion, described resin material is polyvinyl resin or TPUE.
In addition, in described heat conduction cushion, described refrigerating liquid comprises modification monohydric alcohol.
In addition, in described heat conduction cushion, described scheduled volume is every square metre 3000 grams～4000 grams.
In addition, in described heat conduction cushion, the thickness of described upper layer film and described lower membrane is respectively 0.20mm～0.30mm.
In addition, in described heat conduction cushion, the thickness of described heat conduction cushion is 4mm～5mm.
In addition, in described heat conduction cushion, on described heat conduction cushion, be provided with for placing the identified areas of plasma bags.
On the other hand of the present utility model, a kind of blood plasma quick freezer is provided.This blood plasma quick freezer comprises: upper cold drawing and lower cold drawing; Be laid on the one or more heat conduction cushions as described in claim 1～8 on described lower cold drawing.
In addition, described blood plasma quick freezer also comprises: be arranged on the pallet between described lower cold drawing and described heat conduction cushion.
Compared with prior art, according to the technical solution of the utility model, plasma quick freezing function guarantees that each plasma bags is stressed evenly, avoid plasma bags in quick-frozen process, deform or break, and realize that temperature conduction performance is good, heat conduction efficiency is high, can guarantee same batch plasma bags fast, quick-frozen equably, and quick-frozen is effective.
Accompanying drawing explanation
Accompanying drawing described herein is used to provide further understanding of the present utility model, forms the application's a part, and schematic description and description of the present utility model is used for explaining the utility model, does not form improper restriction of the present utility model.In the accompanying drawings:
Fig. 1 is the structural representation of the blood plasma quick freezer of the utility model embodiment;
Fig. 2 is the side sectional view of the blood plasma quick freezer of the utility model embodiment;
Fig. 3 A is the schematic top plan view of the heat conduction cushion of the utility model embodiment;
Fig. 3 B is the cutaway view along the A-A ' line shown in Figure 1A of the heat conduction cushion of the utility model embodiment;
Fig. 4 is the plasma bags of the utility model embodiment cutaway view during by quick-frozen;
Fig. 5 is that the heat conduction cushion of the utility model embodiment is positioned over the state diagram on lower cold drawing;
Fig. 6 is that the plasma bags of the utility model embodiment is positioned over the layout on cold drawing.
The specific embodiment
Main thought of the present utility model is, because the blood plasma quick freezer using at present approximately needs 2 hours by plasma quick freezing to-30 ℃, or the degree with a collection of plasma quick freezing in 1 hour is different, can not guarantee that whole blood plasma all reaches-30 ℃, and whether the DIE Temperature that cannot confirm each plasma bags reach-30 ℃, therefore cannot reach the requirement of GB.In order to solve this technical problem, the utility model adopts the sweat cooling plate (upper cold drawing and lower cold drawing) of two stainless steel materials, and on lower cold drawing, lays heat conduction cushion.First when blood plasma quick freezer is worked, the temperature of cold plate is reached-50 ℃, then plasma sackholder is held between upper cold drawing and heat conduction cushion, lower cold drawing, by reaching the cold plate of-50 ℃, blood plasma is directly carried out to heat conduction.Conventionally, can in 30 minutes, the DIE Temperature of blood plasma be reduced to-30 ℃, then be used in conjunction with the DIE Temperature of monitoring plasma bags as the simulating blood plasma bag of our company's patented product, realize reliably the real-time monitoring to the quick freezing temperature of plasma bags.
For making the purpose of this utility model, technical scheme and advantage clearer, below in conjunction with drawings and the specific embodiments, the utility model is described in further detail.
According to embodiment of the present utility model, provide a kind of blood plasma quick freezer.
Fig. 1 is the structural representation of the blood plasma quick freezer of the utility model embodiment, and Fig. 2 is the cutaway view of the blood plasma quick freezer of the utility model embodiment.As shown in Figure 1 and Figure 2, blood plasma quick freezer can comprise casing 1, refrigeration unit 2, cold plate (3,4), heat conduction cushion 5, control panel 6 and not shown clamping device, elevating mechanism, case lid etc.
<refrigeration unit and cold plate>
As shown in Figure 2, in casing 1 Nei bottom, be provided with refrigeration unit 2, on casing 1 Nei top, be provided with sweat cooling plate, this sweat cooling plate can comprise cold drawing 3 and lower cold drawing 4.Refrigeration unit 2 is connected with cold drawing 4 under upper cold drawing 3 ﹑ respectively by copper pipe and flexible pipe.Wherein, upper cold drawing 3 is fixing cold plate, is installed in the frame of case lid, and lower cold drawing 4 is mobile cold plate, and itself and elevating mechanism are conjointly arranged on the below of cold drawing, by elevating mechanism, it is being moved up and down with the coaxial direction of upper cold drawing.Space between upper cold drawing 3 and lower cold drawing 4 is for placing the plasma bags that needs quick-frozen.The surface temperature that refrigeration unit 2 can be controlled upper cold drawing 3 and lower cold drawing 4 via copper pipe and flexible pipe reaches-50 ℃ to-55 ℃, to provide the low-temperature receiver of-50 ℃ to-55 ℃ to plasma bags by upper cold drawing, lower cold drawing.
<heat conduction cushion>
In order to make to be positioned over each the plasma bags uniform stressed on lower cold drawing 4, avoid plasma bags in quick-frozen process, deform or break, heat conduction cushion 5 can be set on lower cold drawing 4.
Below, with reference to Fig. 3 A and Fig. 3 B, hot formation of conducting cushion 5 is described.
Fig. 3 A is the schematic top plan view of the heat conduction cushion 5 of the utility model embodiment, and Fig. 3 B is the cutaway view along the A-A ' line shown in Fig. 3 A of the heat conduction cushion 5 of the utility model embodiment.
As shown in Figure 3A, overlook and see, heat conduction cushion 5 is rectangular configuration.Fig. 3 B shows along the section of A-A ' line in Fig. 3 A.As shown in Figure 3 B, the main body of heat conduction cushion 5 comprises upper layer film 11, lower membrane 13 and the intermediate cavity 12 between upper layer film 11 and lower membrane 13.Specifically, TPUE) etc. polyethylene) or TPU(Thermoplastic polyurethane upper layer film 11 and lower membrane 13 can be by PE(polyethylene:: the monofilm that low temperature resistant resin forms, intermediate cavity 12 is the cavitys that can be used for packing into refrigerating liquid.By hot sealing process, upper layer film 11 and lower membrane 13 edge are sealed, and a residual opening (not shown).Refrigerant by from this opening to the interior filling of intermediate cavity 12 a certain amount of (appropriate or scheduled volume).Refrigerant is such as being refrigerating liquid (or being called refrigerating medium) or cold-producing medium etc.After the interior populated refrigerant of intermediate cavity 12, this opening is sealed.In preferred version below, refrigerant be take refrigerating liquid and is described in detail as example.
At this, about a certain amount of refrigerating liquid, preferably, take every square metre of filling for example 3000～4000 grams of these refrigerating liquid be suitable amount, to make the integral thickness of heat conduction cushion moderate, and can not cause whole bag surface expansion and cannot conduct in heat and on cushion, place the plasma bags for the treatment of quick-frozen because of thickness is blocked up, yet can not cause plasma bags to be placed on heat conduction cushion as on being directly placed on lower cold drawing and cannot evenly carry out heat and conduct because of thickness is excessively thin.Therefore, the thickness of heat conduction cushion must be moderate, and can tolerate certain pressure, makes heat conduction cushion have good thermal conductivity.
The thickness of upper layer film 11 and lower membrane 13 can be respectively 0.20mm～0.30mm, more preferably, can be respectively 0.20mm～0.25mm.For example, when the thickness of upper layer film 11 and lower membrane 13 is respectively 0.25mm～0.30mm, the integral thickness that is filled with the heat conduction cushion 5 of refrigerating liquid can be 4mm～5mm.
At the refrigerant of heat conduction cushion 5 interior fillings, if adopt refrigerating liquid, it can comprise modification monohydric alcohol.This refrigerating liquid can further include additive, such as being at least one in anticorrosive, mould inhibitor, solubilizer etc.Refrigerating liquid tool has the following advantages: antiseptic and rustproof property is good, and heat conductivity is good, safety and environmental protection, and freezing point is low, good fluidity, specific heat is large, and thermal conductivity factor is high, and ability of cold carrier is strong etc.This refrigerating liquid can be not freeze below at-80 ℃, more than-80 ℃ guaranteeing, is still liquid, has the effect of storage power.Through further for a long time experiment, confirm, refrigerating liquid is filled too much, the bearing pressure and can increase of heat conduction cushion.The refrigerating capacity that refrigerating liquid absorbs is too many, can have influence on the cooling rate of upper and lower cold drawing, and the cooling rate of plasma bags depends on the temperature difference of plasma bags and upper and lower cold drawing, if generally can make plasma bags and the temperature difference of upper and lower cold drawing maintain 20 ℃ of left and right, more satisfactory.Thereby, through experiment, drawing, the loading of refrigerating liquid is preferably 3000～4000 grams every square metre.
Refrigerating liquid has following effect in the utility model.That is:
(1) automatically regulate the height of plasma bags between cold drawing.Due to the material behavior of heat conduction cushion and the characteristics of liquids of refrigerating liquid and the amount of filling moderate, the plasma bags height being placed on heat conduction cushion can be adjusted.
(2) accelerate heat conduction.Owing to having filled the characteristic of the heat conduction cushion of appropriate refrigerating liquid, plasma bags is around all object contact, and the airborne heat conduction that there will not be space to cause, so heat conduction velocity is accelerated.
(3) storage power.In the situation that not using heat conduction cushion, because the refrigerating capacity that the refrigerating capacity of the refrigeration unit configuring is required with respect to the plasma bags of wanting quick-frozen is much bigger, thereby the conduction of the heat between upper and lower cold drawing 3,4 and plasma bags needs the time.When the refrigerating capacity of refrigeration unit has surpassed the amount that plasma bags absorbs, the temperature of upper and lower cold drawing will decline comparatively fast.In order to protect refrigeration unit, need to, when design refrigeration unit, just design in advance the function that when the temperature of upper and lower cold drawing drops to-55 ℃, refrigeration unit can temporarily be shut down.After refrigeration unit is shut down, when the temperature recovery of upper and lower cold drawing is could again start shooting when more than 3 minutes to-45 ℃ and downtime.In the process of shutting down, the temperature of upper and lower cold drawing can be gone up, and can have influence on like this cooling rate of plasma bags.With respect to this; in the situation that using heat conduction cushion; when refrigeration unit is worked, heat conduction cushion can absorb the part refrigerating capacity that plasma bags has little time absorption, and the part refrigerating capacity that heat conduction cushion absorbs when refrigeration unit is shut down is released, and can play and regulate storage cold-working use.Thereby this heat conduction cushion can be also a kind of accumulation of energy heat conduction cushion.
(4) increased the heat transfer area of plasma bags.Owing to having filled up refrigerating liquid in the space between plasma bags and plasma bags, thereby increased the heat transfer area of plasma bags.
Below, with reference to Fig. 4, be described in detail in the effect of plasma bags is carried out to quick-frozen time heat conduction cushion performance.
Fig. 4 is the plasma bags of the utility model embodiment cutaway view during by quick-frozen.
As shown in Figure 4, when quick-frozen plasma bags, by upper cold drawing 3 and lower cold drawing 4, clamp plasma bags 7 and heat conduction cushion 5.By upper cold drawing 3 and lower cold drawing 4, clamp plasma bags 7 and heat conduction cushion 5, the one side contacting with upper cold drawing 3 of plasma bags 7 is exerted pressure into tabular by upper cold drawing 3, the refrigerating liquid that the another side of plasma bags 7 conducts heat in cushion 5 owing to contacting with heat conduction cushion 5 squeezes out, and presents thus the shape of downward protrusion.In this case, by upper cold drawing 3 and lower cold drawing 4, provide low-temperature receiver, and by upper cold drawing 3, lower cold drawing 4 exert pressure (for example: on average each plasma bags is stressed 14 kilograms) carry out heat conduction, a heat conducting part is transmitted to the one side of plasma bags 7 by upper cold drawing 3, heat conducting another part is transmitted to heat conduction cushion 5 by lower cold drawing 4, then via heat conduction cushion 5, is transmitted to the another side of plasma bags 7.
In addition, on the lower cold drawing 4 of blood plasma quick freezer, both can place a heat conduction cushion 5, also can place two above heat conduction cushions 5.For example, in effective refrigeration size of lower cold drawing 4, be about length 1000mm, in the situation of width 600mm, when heat conduction cushion 5 is of a size of: length 600mm, width 500mm, can once be used two heat conduction cushions.And conduct cushion 5 when heat, be of a size of: length 1000mm, width 600mm, can once only be used a heat conduction cushion.
In addition, for the ease of plasma bags is put into blood plasma quick freezer, also can conduct placement tray between cushion 5 and lower cold drawing 4 in heat.Like this, in when operation, just can once heat be conducted to cushion 5 and plasma bags 7 and be placed on and again heat is conducted to cushion 5, plasma bags 7 and pallet and be advanced to together on the lower cold drawing in blood plasma quick freezer later on pallet.In detail,, first plasma bags was placed on pallet in the past, then pallet was advanced in blood plasma quick freezer.With respect to this, when using heat conduction cushion of the present utility model, first heat is conducted to cushion and be placed on pallet, then each plasma bags is placed on heat conduction cushion equably, and then pallet is advanced and in blood plasma quick freezer, carries out quick-frozen.Described pallet is for example the pallet of aluminium alloy or ferroalloy material.
In addition, because the area of heat conduction cushion is identical with the effective area of the refrigeration of upper and lower cold drawing 3,4, plasma bags only need be placed in the scope of heat conduction cushion equably, not overlapping between each plasma bags.Such object is to utilize fully the effective area of refrigeration to place maximum plasma bags.For example, in the situation that the area of heat conduction cushion is 0.6 square metre, the plasma bags that can place at most 35 bags of 200ML.
Fig. 5 is that the heat conduction cushion 5 of the utility model embodiment is positioned over the state diagram on lower cold drawing 4.As shown in Figure 5, in order to maximally utilise the effective area of refrigeration, can conduct on cushion 5 identified areas 8 is set in heat, in order to place plasma bags.When quick-frozen blood plasma, only each plasma bags neatly need be placed in the identified areas 8 of heat conduction cushion 5; Or, first heat is conducted to cushion 5 and be placed in pallet, then plasma bags 7 is placed on heat conduction cushion 5, then pallet is put into blood plasma quick freezer, by the quick-frozen of pressurizeing of upper cold drawing 3 and 4 pairs of plasma bags 7 of lower cold drawing.
<control panel>
As shown in Figure 1, in the front upper place of the casing of blood plasma quick freezer, be provided with control panel 6.Specifically, control panel 6 is positioned at the top of wide of blood plasma quick freezer, control panel 6 adopts the panel computer of one 12 cun, its control section adopts temperature control modules and PLC, adopt three temperature measuring probes to detect respectively, the temperature of lower cold drawing and simulating blood plasma bag, when upper, the temperature of lower cold drawing makes refrigeration unit stop refrigeration simultaneously while reaching-55 ℃, after refrigeration unit is shut down, when upper, more than lower cold drawing temperature all goes back up to-45 ℃ and when downtime surpasses 3 minutes, control refrigeration unit restarts it and proceeds refrigeration, when refrigeration unit has reached predefined cooling time running time, on control panel 6, can demonstrate and arrive the such message of setting-up time and with auditory tone cues.When the detected temperatures of simulating blood plasma bag surpasses-30 ℃, control panel 6 will show the such message of DIE Temperature that has reached plasma bags.As long as no people, for going to operate, stop freezing, these actions will be carried out constantly above, can guarantee like this that the temperature of blood plasma reaches-30 ℃ just can not go back up to again-30 ℃ above (to the requirement of blood plasma, being to preserve need to be placed on low temperature refrigerator after blood plasma is completed by quick-frozen in) after following.The variations in temperature of all run durations (temperature of upper and lower cold drawing and simulating blood plasma bag) all will go on record above, to be ready for use on, can review.
[experiment]
In order to reach better effect, the simulating blood plasma bag that blood plasma quick freezer of the present utility model is used in conjunction with a kind of our company patented product is monitored the temperature of plasma quick freezing.On the bag of simulating blood plasma bag, be provided with the probe pipe that is inserted into bag inner chamber middle part, one end that is inserted into bag inner chamber of this probe pipe is sealed, and its other end opening.In probe pipe, insert temperature sensor, make temperature sensor and liquid isolation.Temperature sensor is connected with the temperature control modules of blood plasma quick freezer, and temperature control modules is controlled by control panel 6.
Experiment purpose is that the test data in the situation of heat conduction cushion and the situation of obsolete heat conduction cushion is used in contrast.
<test 1>
Experiment condition: (1) is not used pallet and heat conduction cushion;
(2) put into the quantity of plasma bags: 35 bags;
(3) change point of the DIE Temperature of monitoring plasma bags: 2
Experimental implementation: the plasma bags that needs quick-frozen is directly placed on the lower cold drawing 4 of blood plasma quick freezer, then carries out quick-frozen operation in the quick-frozen storehouse of blood plasma quick freezer.
Fig. 6 is that the plasma bags of the utility model embodiment is positioned over the layout on lower cold drawing 4, and wherein, T1 and T2 are temperature monitoring points.The data of experiment 1 are as table 1.To time the 30th minute the temperature spread of the blood bag at T1 and T2 two places larger, cooling effect is undesirable.Time the 40th minute, the temperature spread of T1 and T2 is larger.Be difficult to reach the requirement of subzero 30 ℃.
<table 1>
| Sequence number | Time | T1(℃) | T2(℃) | Upper cold drawing (℃) | Lower cold drawing (℃) | Remarks |
| 1 | 0min | ? | ? | ? | ? | ? |
| 2 | 5min | 6.8 | 3.9 | ‐40 | ‐8 | ? |
| 3 | 10min | 0.3 | 0.3 | ‐38 | ‐44 | ? |
| 4 | 12min | ‐1.3 | ‐0.8 | ‐41 | ‐41 | ? |
| 5 | 14min | ‐2.1 | ‐1 | ‐44 | ‐47 | ? |
| 6 | 15min | ‐2.3 | ‐1 | ‐44 | ‐48 | ? |
| 7 | 16min | ‐2.5 | ‐1.1 | ‐46 | ‐47 | ? |
| 8 | 17min | ‐2.9 | ‐1.1 | ‐46 | ‐46 | ? |
| 9 | 18min | ‐3.2 | ‐1.2 | ‐47 | ‐47 | ? |
| 10 | 19min | ‐3.4 | ‐1.2 | ‐50 | ‐50 | Shut down |
| 11 | 20min | ‐4 | ‐1.6 | ‐43 | ‐42 | ? |
| 12 | 22min | ‐4.1 | ‐2.0 | ‐44 | ‐42 | ? |
| 13 | 24min | ‐5.3 | ‐2.2 | ‐48 | ‐48 | ? |
| 14 | 26min | ‐7.8 | ‐2.5 | ‐50.6 | ‐51.4 | Shut down |
| 15 | 28min | ‐9.8 | ‐3.1 | ‐42 | ‐43 | ? |
| 16 | 30min | ‐11.5 | ‐3.1 | ‐43 | ‐42 | ? |
| 17 | 32min | ‐14 | ‐3.6 | ? | ? | Shut down |
| 18 | 36min | ‐18 | ‐4 | ‐40 | ‐40 | ? |
| 19 | 40min | ‐20 | ‐5.4 | ‐50 | ‐50 | Shut down |
<test 2>
Experiment condition: (1) is used pallet, is not used heat conduction cushion;
(2) quantity of putting into plasma bags remains unchanged;
(3) change point of the DIE Temperature of monitoring plasma bags remains unchanged.
Experimental implementation: the plasma bags that needs quick-frozen is placed on pallet, then pallet is advanced in the quick-frozen storehouse of blood plasma quick freezer and carry out quick-frozen operation.
The data of experiment 2 are as table 2.T1 and T2 temperature difference are also larger, and time the 31st minute, T1 has reached the requirement of subzero 30 ℃, and T2 does not reach requirement.
<table 2>
| Sequence number | Time | T1(℃) | T2(℃) | Upper cold drawing (℃) | Lower cold drawing (℃) | Remarks |
| 1 | 0min | 13.7 | 20 | 5.1 | 3.6 | ? |
| 2 | 5min | 5.6 | 8.1 | ‐38 | ‐6.1 | ? |
| 3 | 10min | ‐0.9 | 0.7 | ‐39 | ‐43 | ? |
| 4 | 12min | ‐2.3 | ‐0.8 | ‐40 | ‐41 | ? |
| 5 | 14min | ‐4.8 | ‐1.4 | ‐42 | ‐47 | ? |
| 6 | 15min | ‐6.8 | ‐1.5 | ‐42 | ‐47 | ? |
| 7 | 16min | ‐3.4 | ‐1.5 | ‐43 | ‐46 | ? |
| 8 | 17min | ‐13.5 | ‐1.5 | ‐44 | ‐45 | ? |
| 9 | 18min | ‐16.5 | ‐1.6 | ‐45 | ‐48 | ? |
| 10 | 19min | ‐19.2 | ‐1.9 | ‐47 | ‐48 | ? |
| 11 | 20min | ‐21.5 | ‐2.2 | ‐48 | ‐52 | Shut down |
| 12 | 22min | ‐24.8 | ‐2.5 | ‐48 | ‐49 | ? |
| 13 | 24min | ‐26.5 | ‐2.0 | ‐50 | ‐52 | Shut down |
| 14 | 26min | ‐27.3 | ‐11.7 | ‐47 | ‐42 | ? |
| 15 | 28min | ‐27.4 | ‐15.3 | ‐47 | ‐49 | ? |
| 16 | 30min | ‐29 | ‐19.4 | ‐53 | ‐35 | ? |
| 17 | 31min | ‐30 | ‐21 | ? | ? | ? |
| ? | ? | ? | ? | ? | ? | ? |
<test 3>
Experiment condition: (1) is not used pallet, is only used heat conduction cushion;
(2) quantity of putting into plasma bags remains unchanged;
(3) change point of the DIE Temperature of monitoring plasma bags remains unchanged.
Experimental implementation: heat is conducted on the lower cold drawing that cushion is directly placed on blood plasma quick freezer, then plasma bags is placed on equably on heat conduction cushion, carry out quick-frozen operation in the quick-frozen storehouse of blood plasma quick freezer.
The data of experiment 3 are as table 3.The temperature difference of the plasma bags at T1 and T2 place is little, and time the 22nd minute, T1 and T2 have all reached the requirement of subzero 30 ℃.And the quick-freeze speed of plasma bags is very fast, shuts down number of times and also obviously reduce.
<table 3>
| Sequence number | Time | T1(℃) | T2(℃) | Upper cold drawing (℃) | Lower cold drawing (℃) | Remarks |
| 1 | |
6 | 6 | 7 | 6.6 | ? |
| 2 | 5min | 7 | 5 | ‐40 | ‐9 | ? |
| 3 | 10min | ‐4.1 | ‐5.3 | ‐39 | ‐45 | ? |
| 4 | 12min | ‐4.5 | ‐5.9 | ‐42 | ‐42 | ? |
| 5 | 14min | ‐5.5 | ‐9.6 | ‐44 | ‐48 | ? |
| 6 | 15min | ‐6.3 | ‐10.1 | ‐46 | ‐47 | ? |
| 7 | 16min | ‐6.9 | ‐11.7 | ‐46 | ‐46 | ? |
| 8 | 17min | ‐8.1 | ‐12 | ‐47 | ‐47 | ? |
| 9 | 18min | ‐9.5 | ‐13 | ‐47 | ‐47 | ? |
| 10 | 19min | ‐11.3 | ‐16.9 | ‐49 | ‐49 | ? |
| 11 | 20min | ‐21 | ‐24 | ‐50 | ‐50 | Shut down |
| 12 | 22min | ‐30 | ‐33 | ‐48 | ‐49 | ? |
| 13 | 24min | ? | ? | ? | ? | ? |
| 14 | 26min | ? | ? | ? | ? | ? |
<test 4>
Experiment condition: (1) is used pallet and heat conduction cushion;
(2) quantity of putting into plasma bags remains unchanged;
(3) change point of the DIE Temperature of monitoring plasma bags remains unchanged.
Experimental implementation: heat is conducted to cushion and be placed on pallet, the plasma bags that needs quick-frozen is placed on heat conduction cushion, then all advance in the quick-frozen storehouse of blood plasma quick freezer and carry out quick-frozen operation.
The data of experiment 4 are as table 4.The temperature difference of plasma bags that can find out T1 and T2 place is little, and in the time of the 26th minute, T1 and T2 have all reached subzero 30 ℃ of following requirements.In the time of the 30th minute, T1 and T2 have reached the requirement that approaches subzero 40 ℃.And plasma bags all can meet the requirements of rapidly quick freezing temperature, and during without shutdown, restart, and then can save the energy, increase service life of equipment.
<table 4>
| Sequence number | Time | T1(℃) | T2(℃) | Upper cold drawing (℃) | Lower cold drawing (℃) | Remarks |
| 1 | |
6 | 6.3 | 7 | 6.5 | ? |
| 2 | 5min | 3.4 | 2.7 | ‐35.6 | ‐1.7 | ? |
| 3 | 10min | ‐3.1 | ‐5.3 | ‐40.5 | ‐41.4 | ? |
| 4 | 12min | ‐4 | ‐6.9 | ‐38.8 | ‐38.9 | ? |
| 5 | 14min | ‐5.3 | ‐9.6 | ‐44 | ‐39 | ? |
| 6 | 15min | ‐6.3 | ‐10.2 | ‐44 | ‐42 | ? |
| 7 | 16min | ‐5.1 | ‐10.5 | ‐44 | ‐41 | ? |
| 8 | 17min | ‐7.8 | ‐11 | ‐42 | ‐42 | ? |
| 9 | 18min | ‐8.9 | ‐13 | ‐44 | ‐46 | ? |
| 10 | 19min | ‐10.3 | ‐16.9 | ‐44 | ‐48 | ? |
| 11 | 20min | ‐11 | ‐24 | ‐46 | ‐46.7 | ? |
| 12 | 22min | ‐18 | ‐33 | ‐48 | ‐48 | ? |
| 13 | 24min | ‐28.4 | ‐39.8 | ‐51.3 | ‐49.8 | ? |
| 14 | 26min | ‐33.5 | ‐39.2 | ‐42 | ‐42 | ? |
| 15 | 28min | ‐34.1 | ‐37.7 | ‐43 | ‐43 | ? |
| 16 | 30min | ‐37.5 | ‐39 | ‐48.9 | ‐49 | ? |
| ? | ? | ? | ? | ? | ? | ? |
Conclusion: can obviously find out by above four groups of experiments, using the experiment effect of heat conduction bag is very large with not using the experiment effect difference of heat conduction bag.
By adopting heat conduction cushion of the present utility model, the beneficial effects such as the quick-frozen efficiency quick-freeze speed high, that guarantee plasma bags uniform stressed, each plasma bags that can obtain blood plasma quick freezer is consistent, heat transfer area increase.Specifically the reasons are as follows:
1, because blood plasma quick freezer has been used hot conduction cushion, make plasma bags uniform stressed, avoided the situation that quick-frozen effect is inconsistent and plasma bags deforms or breaks in quick-frozen process of each plasma bags.
2, the skin due to heat conduction cushion is the resin material of ultralow temperature, in heat conduction cushion, refrigerating liquid is housed, and can not break, and temperature conduction performance is good, can guarantee the quick quick-frozen of plasma bags so this heat is conducted cushion in the scope of-80 ℃, and quick-frozen is effective.
3, owing to conducting on cushion and be provided with for placing the identified areas of plasma bags in heat, so can fitly put plasma bags on heat conduction cushion in advance, then plasma bags and heat conduction cushion integral body are placed on cold plate, thereby avoided putting irregular and causing plasma bags that extruding mutually occurs by plasma bags, guaranteed plasma bags quick-frozen equably.
4, in the time of on plasma bags being placed in to heat conduction cushion, in quick-frozen process, the extruding of cold drawing under the Shang ﹑ of You Yu, can increase plasma bags and hot contact area of conducting cushion, and heat conduction efficiency improves thus.
The foregoing is only embodiment of the present utility model, be not limited to the utility model, for a person skilled in the art, the utility model can have various modifications and variations.All within spirit of the present utility model and principle, any modification of doing, be equal to replacement, improvement etc., within all should being included in claim scope of the present utility model.
Claims (10)
1. for a heat conduction cushion for blood plasma quick freezer, comprising:
Upper layer film and lower membrane;
Between described upper layer film and lower membrane, there is intermediate cavity, in described intermediate cavity, be filled with the refrigerant of scheduled volume;
Described upper layer film and lower membrane seal through hot sealing process.
2. heat according to claim 1 is conducted cushion, wherein,
Described upper layer film and lower membrane adopt resin material;
Described refrigerant comprises refrigerating liquid.
3. heat according to claim 2 is conducted cushion, wherein,
Described resin material is polyvinyl resin or TPUE.
4. heat according to claim 2 is conducted cushion, wherein,
Described refrigerating liquid comprises modification monohydric alcohol.
5. heat according to claim 1 is conducted cushion, wherein,
Described scheduled volume is every square metre 3000 grams～4000 grams.
6. heat according to claim 1 is conducted cushion, wherein,
The thickness of described upper layer film and described lower membrane is respectively 0.20mm～0.30mm.
7. heat according to claim 1 is conducted cushion, wherein,
The thickness of described heat conduction cushion is 4mm～5mm.
8. heat according to claim 1 is conducted cushion, wherein,
On described heat conduction cushion, be provided with for placing the identified areas of plasma bags.
9. a blood plasma quick freezer, comprising:
Upper cold drawing and lower cold drawing;
Be laid on the one or more heat conduction cushions as described in claim 1～8 on described lower cold drawing.
10. blood plasma quick freezer according to claim 9, also comprises:
Be arranged on the pallet between described lower cold drawing and described heat conduction cushion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320373810.2U CN203396201U (en) | 2013-06-27 | 2013-06-27 | Heat-conducting cushion and plasma instant freezer using same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320373810.2U CN203396201U (en) | 2013-06-27 | 2013-06-27 | Heat-conducting cushion and plasma instant freezer using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203396201U true CN203396201U (en) | 2014-01-15 |
Family
ID=49907726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320373810.2U Withdrawn - After Issue CN203396201U (en) | 2013-06-27 | 2013-06-27 | Heat-conducting cushion and plasma instant freezer using same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203396201U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104251597A (en) * | 2013-06-27 | 2014-12-31 | 武汉贝索医疗器械有限公司 | Heat conduction cushion and blood plasma instant freezer using cushion |
| CN104374164A (en) * | 2014-11-07 | 2015-02-25 | 青岛澳柯玛超低温冷冻设备有限公司 | Contact type low temperature quick-freezing box |
| CN106403494A (en) * | 2016-08-31 | 2017-02-15 | 深圳市爱康生物科技有限公司 | Heat conduction cushion tray |
-
2013
- 2013-06-27 CN CN201320373810.2U patent/CN203396201U/en not_active Withdrawn - After Issue
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104251597A (en) * | 2013-06-27 | 2014-12-31 | 武汉贝索医疗器械有限公司 | Heat conduction cushion and blood plasma instant freezer using cushion |
| CN104251597B (en) * | 2013-06-27 | 2016-04-06 | 武汉贝索医疗器械有限公司 | Heat transfer cushion and use the blood plasma quick freezer of this cushion |
| CN104374164A (en) * | 2014-11-07 | 2015-02-25 | 青岛澳柯玛超低温冷冻设备有限公司 | Contact type low temperature quick-freezing box |
| CN104374164B (en) * | 2014-11-07 | 2016-08-17 | 青岛澳柯玛超低温冷冻设备有限公司 | A kind of contact low-temperature quick-freezing case |
| CN106403494A (en) * | 2016-08-31 | 2017-02-15 | 深圳市爱康生物科技有限公司 | Heat conduction cushion tray |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN203396201U (en) | Heat-conducting cushion and plasma instant freezer using same | |
| CN1315374C (en) | Systems and methods for freezing and storing biopharmaceutical material | |
| CN104206933A (en) | Oil absorbing box device | |
| CN104251597B (en) | Heat transfer cushion and use the blood plasma quick freezer of this cushion | |
| CN204587688U (en) | A kind of storage equipment of Multifunction biologics | |
| CN213567016U (en) | Packing carton upper cover and lower cover suitable for quality control article are cold-stored to be preserved | |
| CN202075048U (en) | Simulated blood bag | |
| CN104236158A (en) | Semiconductor refrigerating device capable of measuring undercooling point and freezing point | |
| KR102357006B1 (en) | How to freeze a liquid | |
| CN115751815A (en) | Liquid nitrogen refrigerator with multi-temperature storage and switching method | |
| CN209355547U (en) | A kind of cold storage plant | |
| CN202153093U (en) | Tray used on shelf of vacuum refrigerating drier | |
| CN214190915U (en) | Sperm cryopreservation box and inner box taking-out device | |
| CN213801136U (en) | Sample storage device for blood station clinical laboratory | |
| CN213736289U (en) | Puncture type medicine transfer device | |
| CN213414919U (en) | Transfer box with inactivation function | |
| CN204202236U (en) | A kind of semiconductor cooling device measuring undercooling point or freezing point | |
| CN204176991U (en) | Cold storage box and cold-storage device | |
| CN206572837U (en) | Refrigerator cold-storage is around film evaporator | |
| CN206231864U (en) | A kind of dismountable new accumulator of low temperature molecular experiment is put | |
| CN216371788U (en) | Whole formula self-adaptation clamping device that cuts | |
| CN209310363U (en) | Dual-purpose semiconductor refrigerating plant | |
| CN217737665U (en) | Refrigerator for producing and processing frozen fresh products | |
| CN215624083U (en) | Portable multi-temperature-zone combined specimen box | |
| CN209617960U (en) | A kind of medicine safety collar control supervisory systems |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20140115 Effective date of abandoning: 20160406 |
|
| C25 | Abandonment of patent right or utility model to avoid double patenting |