CN213736289U - Puncture type medicine transfer device - Google Patents

Puncture type medicine transfer device Download PDF

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Publication number
CN213736289U
CN213736289U CN202022787144.XU CN202022787144U CN213736289U CN 213736289 U CN213736289 U CN 213736289U CN 202022787144 U CN202022787144 U CN 202022787144U CN 213736289 U CN213736289 U CN 213736289U
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China
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cavity
freezing
refrigerant
housing cover
insulation
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CN202022787144.XU
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Chinese (zh)
Inventor
许波
周宏珍
任素桃
康玲
陈晓云
张丽芬
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Southern Hospital Southern Medical University
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Southern Hospital Southern Medical University
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Abstract

The utility model discloses a puncture type drug transfer device, which comprises an insulation can, a storage box and a freezing grid, wherein the storage box is arranged in the insulation can; the freezing check is arranged in the insulation can and is located between the inner wall of insulation can and the outer wall of depositing the case, and the freezing check has the baffle that falls into first cavity and second cavity with inside, first cavity and second cavity intercommunication, and first cavity is used for placing the reactant through water-soluble plastic film, and the second cavity is used for placing the refrigerant, and the freezing check is equipped with pjncture needle and push plate. The utility model discloses a pressing plate is pressed down, and the pjncture needle pierces through the refrigerant, and in the refrigerant flowed first cavity from second cavity and first hole, the water-soluble plastic film on reactant surface dissolved for refrigerant and reactant mix and take place endothermic reaction, reach refrigerated effect, keep cold-stored effect in the messenger deposits the case, but wide application in medical instrument technical field.

Description

Puncture type medicine transfer device
Technical Field
The utility model belongs to the technical field of medical instrument, more specifically say, relate to a impaling formula medicine transfer device.
Background
The clinical test of the medicine refers to any systematic research of the medicine on human bodies (patients or healthy volunteers), and is vital to the temperature monitoring of the test medicine in the whole process of the clinical test of the medicine, and each clinical test of the medicine needs to record the temperature of the test medicine in the processes of transportation, transportation and storage in detail, so that the environment where the test medicine is located is always in the specified temperature range, and the safety, the stability and the effectiveness of the medicine are ensured. Particularly, test drugs (such as insulin glargine injection, adalimumab, infliximab and the like) stored at low temperature always need to be placed in an environment with the temperature of 2-8 ℃.
At present, many test medicines are centrally managed, so the tests are uniformly placed in a central pharmacy of a clinical medicine testing institution, when the test medicines are used, a researcher takes the test medicines from the central pharmacy and transfers the test medicines to a department for a subject to use, and a common method is to firstly place the medicines in an insulation box or a foam box with a heat insulation effect and then place a plurality of ice blocks or ice bags in the medicines and the insulation box. The ice blocks in the incubator are too few, and because the transport distance is long, particularly in hot summer in the south, the outdoor temperature is high, and the test drugs in the incubator easily exceed the specified storage temperature of the drugs; the ice blocks are placed too much in the incubator, and the test drugs contact the ice blocks, so that the temperature of the drugs is lower than the specified storage temperature of the drugs, and the phenomenon of drug overtemperature occurs. According to the regulation of the clinical trial administration of the medicine, once the medicine is over-temperature, the medicine can not be delivered to the testee for use, and the testee participating in the clinical trial of the medicine can not take the medicine on time, thus seriously affecting the clinical trial process.
SUMMERY OF THE UTILITY MODEL
The utility model discloses a main aim at provides a impaling formula medicine transfer device, through pressing the mode of impaling, impales the refrigerant, and in the refrigerant flowed to first cavity, it was dissolved with water-soluble plastic film for refrigerant and reactant mix and take place endothermic reaction, reach refrigerated effect.
According to the utility model discloses a first aspect provides a puncture type medicine transfer device, include:
a heat preservation box;
the storage box is arranged in the heat insulation box;
the freezing check, the freezing check is arranged in the insulation can and is located the inner wall of insulation can and deposit between the outer wall of case, the freezing check has the baffle that falls into first cavity and second cavity with inside, the second cavity sets up in first cavity top, first cavity and second cavity pass through the first hole intercommunication of baffle, first cavity is used for placing the reactant through water-soluble plastic film, the second cavity is used for placing the refrigerant, the freezing check is equipped with the pjncture needle that can impale the refrigerant of placing at the second cavity and the pressing plate that orders about the pjncture needle removal.
In a specific embodiment of the present invention, the freezing compartment includes a housing and a housing cover, one end of the housing cover is mounted to the housing through a second hinge, the other end of the housing cover is connected to the housing through a concave-convex groove structure, the pressing plate is located outside the housing cover, and a spring is provided between the pressing plate and the housing cover.
In a particular embodiment of the invention, the inner wall of the housing is provided with a support plate for supporting the partition.
In a specific embodiment of the present invention, the puncture needle is provided with a limiting plate.
In a specific embodiment of the present invention, the housing cover is provided with at least one check valve, and the housing cover communicates with the outside of the housing cover through the check valve.
In a specific embodiment of the present invention, a water absorbing layer is disposed below the check valve.
In a particular embodiment of the present invention, the incubator has an incubator lid, and the incubator lid has at least one outlet for accessing the freezing compartment.
In a particular embodiment of the invention, a protective cover is hinged above the outlet.
In a particular embodiment of the present invention, the storage box is provided with a first temperature sensor for monitoring the temperature of the storage box, the heat preservation box is provided with a display screen for displaying the temperature and the temperature variation line in the storage box.
The utility model discloses a technical scheme has following advantage or one of beneficial effect at least among the above-mentioned technical scheme: the utility model discloses a freezing check with piercing depth, it is down pressed down according to the clamp plate, and the pjncture needle pierces through the refrigerant, and in the refrigerant flowed first cavity from second cavity and first hole, dissolved the water-soluble plastic film on reactant surface for refrigerant and reactant mix and take place endothermic reaction, reach refrigerated effect, make and keep cold-stored effect in the case of depositing, but the utility model discloses but wide application in medical instrument technical field.
Drawings
The present invention will be further described with reference to the accompanying drawings and examples;
fig. 1 is a schematic structural diagram of the present invention;
fig. 2 is a top view of the present invention;
fig. 3 is a schematic structural diagram of a freezing compartment of the present invention.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the accompanying drawings are exemplary only for the purpose of explaining the present invention, and should not be construed as limiting the present invention.
In the description of the present invention, it should be understood that the orientation or positional relationship indicated with respect to the orientation description, such as up, down, front, rear, left, right, etc., is based on the orientation or positional relationship shown in the drawings, and is only for convenience of description and simplification of description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
In the description of the present invention, a plurality of means are one or more, a plurality of means are two or more, and the terms greater than, less than, exceeding, etc. are understood as not including the number, and the terms greater than, less than, within, etc. are understood as including the number. If the first and second are described for the purpose of distinguishing technical features, they are not to be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more features.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the term "connected" is to be interpreted broadly, and may be, for example, a fixed connection or a movable connection, a detachable connection or a non-detachable connection, or an integral connection; may be mechanically connected, may be electrically connected or may be in communication with each other; they may be directly connected or indirectly connected through intervening media, or may be connected through one or more other elements or indirectly connected through one or more other elements or in an interactive relationship between two elements.
The following disclosure provides many different embodiments or examples for implementing different aspects of the invention.
Referring to fig. 1 to 3, the medicine transfer box with the pressing type refrigeration function comprises an insulation box 19, a storage box 18 and a freezing grid 17, wherein the storage box 18 is used for placing medicines, the storage box 18 is arranged in the insulation box 19, the freezing grid 17 is provided with a puncture needle 5, a second cavity 15 for storing a refrigerant and a first cavity 14 for reversely storing a reactant, the puncture needle 5 punctures the refrigerant, the refrigerant flows into the first cavity 14 from the second cavity 15 and the first hole 13, a water-soluble plastic film on the surface of the reactant is dissolved, the refrigerant and the reactant are mixed to generate an endothermic reaction, and the refrigeration effect of the storage box 18 is achieved.
A plurality of outlets 25 are formed in a cover 24 of the incubator, the freezing grids 17 can be placed into the incubator 19 through the outlets 25, one freezing grid 17 corresponds to one outlet 25, an operator can press the freezing grid 17 from the outlet 25, the refrigerant flows into the first cavity 14 from the second cavity 15 and the first hole 13, the water-soluble plastic film on the surface of the reactant is dissolved, the refrigerant and the reactant are mixed to generate an endothermic reaction, and the operator can replace the pressing freezing grid 17 from the outlet 25. The protective cover 26 is arranged above the outlet 25, the protective cover 26 is arranged on the insulating box cover 24 in a turnover mode, the protective cover 26 is installed with the insulating box cover 24 through a third hinge, the freezing lattice 17 can be conveniently replaced by opening the protective cover 26, the freezing lattice 17 can be protected by closing the protective cover 26, and the puncture device is prevented from puncturing the reactant and the refrigerant to generate an endothermic reaction due to the fact that the reactant and the refrigerant are touched by mistake.
The lateral wall of insulation can 19 is provided with the intermediate layer, and it has the heat preservation material to fill in the intermediate layer, and specifically, the heat preservation material adopts polyurethane foam. The side wall of the heat preservation box 19 is made of hard wear-resistant materials, so that the side wall of the heat preservation box 19 is prevented from being broken due to abrasion. The incubator lid 24 is hinged to the incubator 19 by a first hinge 23, and the incubator lid 24 is fixed to the incubator 19 by a lock 28 for closing the incubator 19.
When the medicine is transported, the storage box 18 is placed into the refrigerator, the medicine is placed when the storage box 18 reaches the medicine storage temperature, then the storage box 18 is placed into the heat insulation box 19, and the heat insulation effect of the heat insulation box 19 further maintains the low-temperature environment in the storage box 18. When the low temperature strength is insufficient, the freezing compartment 17 is pressed to cause endothermic reaction, resulting in a lower low temperature storage environment, and also a low temperature environment that can last for a longer time.
Deposit case 18 and include box 21 and case lid 22, it is fixed through magnetic adsorption between case lid 22 and the box 21, and the lateral wall of box 21 has the heat preservation effect, and specifically, the outside parcel of box 21 has the heat preservation, and the heat preservation includes cotton thing and aluminium foil tin paper. The inner side of the box body 21 is made of a hard material with good heat conduction, and specifically, the side wall of the box body 21 is made of a single-layer plastic, organic glass or metal material. The side wall of the box body 21 is provided with an interlayer, the interlayer on the side wall of the box body 21 is filled with buffer substances, and the buffer substances are water or sodium carboxymethyl cellulose solution. The cover 22 is a double-layer structure, and particularly, the cover 22 is a double-layer vacuum transparent organic glass, which facilitates observation of the drug in the storage compartment 18 through the cover 22.
During the transportation medicine, insulation can 19 can effectively protect and maintain the temperature of depositing the environment, because the specific heat capacity of depositing buffer substance in case 18 is great, only buffer substance absorbs or releases a large amount of ability like the back, buffer substance's temperature just can rise or descend, just can influence the ambient temperature that the medicine was deposited, simultaneously, deposit the heat preservation of 18 outsides of case and make buffer substance and the relative isolation of the environment in the insulation can 19, further reduce the temperature suzhe insulation can 19's of depositing buffer substance's in the case 18 internal environment temperature change and the range that changes, thereby improve buffer substance's cushioning effect, reduce the temperature difference change of medicine storage environment, increase the stability of storage ambient temperature. When the freezing grids 17 and the reactor are taken and placed and an endothermic reaction occurs, the temperature in the storage box 18 is ensured not to be too high or too low due to the buffer effect of the heat-insulating layer and the buffer substance on the side wall of the storage box 18.
The freezing grids 17 are made of hard materials with good heat conduction, specifically, the hard materials are organic glass, plastics or metals. The freezer compartment 17 is movably arranged in the heat-insulating box 19.
It is understood that the freezing compartment 17 is provided in one or more. If the number of the freezing lattices 17 is multiple, the inner wall of the heat preservation box 19 is provided with a plurality of interval parts, and one freezing lattice 17 is arranged between two adjacent interval parts; if the freezing compartment 17 is provided in plurality, an outlet 25 and a protective cover 26 are provided on the insulation box cover 24 corresponding to one freezing compartment 17.
With reference to the figures, the freezing compartment 17 includes a housing 2, a housing cover 1, a puncture needle 5, a pressing plate 3, a check valve 12, a partition plate 6, and a support plate 7.
Further, shell lid 1 is located shell 2 top, and shell lid 1 sets up on shell 2 with overturning, and shell lid 1 one side is passed through second hinge 8 and is installed with shell 2, and shell lid 1 other one side is connected through unsmooth draw-in groove structure 11, opens the convenient refrigerant and the reactant of changing in the shell 2 of shell lid 1, and when closing shell 2, unsmooth draw-in groove structure 11 makes the tight knot of shell lid 1 on shell 2. Wherein, the concave-convex card slot structure 11 comprises a convex block arranged on the shell cover 1 and a groove arranged on the shell 2. When the refrigerating reaction occurs and the freezing compartment 17 is taken out, the housing cover 1 is not separated from the housing 2, and the outflow of the substance in the housing 22 is prevented. Be equipped with check valve 12 on the shell lid 1, the shell lid 1 makes the external world communicate with each other in the shell lid 1 through check valve 12, and during the refrigeration reaction, the gas that produces can be discharged from check valve 12, be provided with layer 9 that absorbs water in the shell lid 1, layer 9 that absorbs water sets up in check valve 12 below, specifically, layer 9 that absorbs water is bilayer structure, and the surface that absorbs water layer 9 is provided with non-woven fabrics or foraminiferous plastic slab. Sponge or cotton is filled in the interlayer of the water absorption layer 9 for absorbing water generated during the refrigeration reaction, and meanwhile, the water absorption layer 9 can also reduce the entry of bubbles generated during the refrigeration reaction into the one-way valve 1212.
Puncture needle 5 lug connection is on pressing the board 3, puncture needle 5 is located between shell lid 1 and baffle 6, puncture needle 5 can reciprocate in shell lid 1, puncture needle 5 top is connected with pressing the board 3, there is the limiting plate in the middle of the puncture needle 55, the limiting plate is located shell lid 1. The puncture needle 5 is used for puncturing a film on the surface of the refrigerant placed on the partition plate 6.
The pressing plate 3 is positioned above the shell 2, a spring 4 is arranged between the pressing plate 3 and the shell 2, and when the pressing plate 3 moves downwards, the puncture needle 5 also moves downwards along with the pressing plate. After the puncture needle 5 punctures the film coated on the surface of the refrigerant, the spring 4 jacks up the puncture needle 5. The limit plate on the puncture needle 5 limits the extending range of the spring 4, and ensures that the puncture needle 5 is always fixed in the second cavity 15.
The shell 2 is a hollow cuboid, and a supporting plate 7 is arranged on the inner side wall of the shell 2. A first cavity 14 is formed between the supporting plate 7 and the bottom of the shell 2, a reactant is placed in the first cavity 14, preferably ammonium bicarbonate (NH4HCO3) powder, and the ammonium bicarbonate (NH4HCO3) powder is hermetically wrapped into blocks by a water-soluble plastic film. The encapsulated ammonium bicarbonate (NH4HCO3) powder both prevents deliquescence within the first chamber 14 and facilitates replacement by the operator. So that the freezing compartment 17 can be reused.
The baffle 6 is located shell 2, baffle 6 is located backup pad 7, and baffle 6 is acidproof plastic slab, there are a plurality of first hole 13 on the baffle 6, has placed the refrigerant on the baffle 6, and the refrigerant is preferred acetic acid, and acetic acid is sealed by acidproof plastics or elastic rubber film and wraps up the piece. The acetic acid solution wrapped in blocks in a sealing way can avoid the acetic acid solution from seeping outwards and is convenient for operators to replace.
During refrigeration, an operator moves the pressing plate 3 downwards, the puncture needle 5 punctures the film on the surface of the acetic acid, the acetic acid flows into the first cavity 14 through the first hole 13 on the partition plate 6, the water-soluble plastic film on the surface of the ammonium bicarbonate is dissolved, and the acetic acid is contacted with the ammonium bicarbonate and generates endothermic reaction, so that the refrigeration effect is achieved.
The storage compartment 18 is provided with a first temperature sensor 20, the first temperature sensor 20 being adapted to monitor the temperature of the storage compartment 18.
The incubator lid 24 is provided with a display 27, and the display 27 is used for displaying the temperature in the storage box 18 and displaying the temperature change curve in the storage box 18.
While embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims (9)

1. A piercing drug delivery device, comprising:
a heat preservation box;
the storage box is arranged in the heat insulation box;
the freezing check, the freezing check is arranged in the insulation can and is located the inner wall of insulation can and deposit between the outer wall of case, the freezing check has the baffle that falls into first cavity and second cavity with inside, the second cavity sets up in first cavity top, first cavity and second cavity pass through the first hole intercommunication of baffle, first cavity is used for placing the reactant through water-soluble plastic film, the second cavity is used for placing the refrigerant, the freezing check is equipped with the pjncture needle that can impale the refrigerant of placing at the second cavity and the pressing plate that orders about the pjncture needle removal.
2. The transpierce drug delivery device according to claim 1, wherein the freezing chamber comprises a housing and a housing cover, one end of the housing cover is attached to the housing by a second hinge, the other end of the housing cover is connected by a male-female snap groove structure, the pressing plate is located outside the housing cover, and a spring is provided between the pressing plate and the housing cover.
3. The pierced drug transfer device of claim 2 wherein the inner wall of the housing is provided with a support plate for supporting the septum.
4. The piercing drug delivery device of claim 2, wherein the piercing needle is provided with a stop plate.
5. The pierced drug delivery device of claim 2, wherein the housing cover is provided with at least one-way valve, and the housing cover communicates the inside and the outside of the housing cover through the one-way valve.
6. The pierced drug delivery device of claim 5 wherein a water absorbent layer is disposed below the one-way valve.
7. The piercing drug delivery device of claim 1, wherein the incubator has an incubator lid with at least one outlet for accessing a freezing compartment.
8. The pierced drug transfer device of claim 7 wherein a protective cover is hinged over the exit port.
9. The piercing drug transfer device of claim 1, wherein the storage bin is provided with a first temperature sensor for monitoring the temperature of the storage bin, and the incubator is provided with a display screen for displaying the temperature and temperature profile in the storage bin.
CN202022787144.XU 2020-11-26 2020-11-26 Puncture type medicine transfer device Active CN213736289U (en)

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Application Number Priority Date Filing Date Title
CN202022787144.XU CN213736289U (en) 2020-11-26 2020-11-26 Puncture type medicine transfer device

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Application Number Priority Date Filing Date Title
CN202022787144.XU CN213736289U (en) 2020-11-26 2020-11-26 Puncture type medicine transfer device

Publications (1)

Publication Number Publication Date
CN213736289U true CN213736289U (en) 2021-07-20

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CN202022787144.XU Active CN213736289U (en) 2020-11-26 2020-11-26 Puncture type medicine transfer device

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114803069A (en) * 2022-04-20 2022-07-29 北京黎马敦太平洋包装有限公司 A packing box for printing and dyeing material

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114803069A (en) * 2022-04-20 2022-07-29 北京黎马敦太平洋包装有限公司 A packing box for printing and dyeing material
CN114803069B (en) * 2022-04-20 2024-04-02 北京黎马敦太平洋包装有限公司 Packaging box for printing and dyeing materials

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