CN203388854U - Olfaction stimulus device for PD (Parkinson's Disease) patient magnetic resonance detection - Google Patents

Olfaction stimulus device for PD (Parkinson's Disease) patient magnetic resonance detection Download PDF

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CN203388854U
CN203388854U CN201320460699.0U CN201320460699U CN203388854U CN 203388854 U CN203388854 U CN 203388854U CN 201320460699 U CN201320460699 U CN 201320460699U CN 203388854 U CN203388854 U CN 203388854U
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glass
scale
agent accommodation
glass tubing
magnetic resonance
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CN201320460699.0U
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徐仁泗
邓霞
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First Affiliated Hospital of Nanchang University
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First Affiliated Hospital of Nanchang University
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Abstract

An olfaction stimulus device for PD (Parkinson's Disease) patient magnetic resonance detection is formed by an olfactory agent accommodating bottle (3), a large-sized injector (3), a flexible long ventilation glass pipe (4), a flexible short ventilation glass pipe (5), a large-sized injector eduction glass pipe (11), a glass guide pipe (12) which enters into the olfactory agent accommodating bottle, a glass pipe (13) which is guided from the olfactory agent accommodating bottle, glass valves (6), (7), a bifurcated pipe, a scale (9) and a base (8). The olfaction stimulus device for the PD patient magnetic resonance detection has the advantages of accurately giving smell stimulation of the olfactory agent which do not contain other gas to patients through the large-sized injector, improving stimulated purity of the patients, accordingly improving stimulation accuracy and the reliability during detection, accurately measuring olfactory disorder symptoms of the PD patients systematically and initiatively, accurately distinguishing different encephalic regions and stimulation degrees in the later analysis and being applied to olfactory function detection of the PD patients through magnetic resonance detection.

Description

Parkinsonian's magnetic resonance detects olfactory stimulation device
technical field
The present invention relates to when parkinson patient functional MRI (fMRI) detects olfactory function needs matching used olfactory stimulation device, belongs to Neurology Department medical treatment technical field of auxiliary facilities.
background technology
Along with to the going deep into of Parkinsonian research, increasing evidence shows, have olfactory function infringement, and the bilateral olfactory sensation extent of damage is the same, not affected by anti-Parkinson Drug therapy up to 80~90%PD patient.Olfactory function is impaired in PD, almost becomes one of symptom common as motor symptoms (as static tremor), and the time that its time of occurrence occurs than motor symptoms is at least done sth. in advance 4 years.
Many factors and pathological conditions can affect normal olfactory function.In the world, in recent years, olfactory sensation problem was just starting one research boom in neural field.Olfactory sensation damages and also can in multiple sacred disease, find, as Alzheimer, and multiple sclerosis, Huntington Chorea and motor neuron.Yet being seen olfactory sensation disease is often judged by accident or is seldom associated with clinical examination.In nervus centralis disease, may be very useful in the early diagnosis of nervus centralis disease to the early diagnosis of olfactory disorder.
Early diagnosis parkinson disease, observe the course of disease that is conducive to later stage disease and treatment, very important to Parkinsonian treatment.If this olfactory disorder can obtain EARLY RECOGNITION in parkinson disease, and differentiate mutually with other olfactory disordeies that also occur in early days the disease of olfactory disorder, olfactory disorder will be probably as Parkinsonian early diagnosis index.And the most important condition of realizing this goal is exactly, the accurate detection to olfactory function.
Recent years, in the fMRI research of parkinson patient's olfactory function that starts gradually upsurge, the accurate identification of parkinson patient's olfactory sensation active region seems very important.Yet to the prerequisite basis of the accurate identification of parkinson patient's olfactory sensation active region, be the precise positioning to head olfactory center in MRI function state scanning process, and the precise positioning of head olfactory center depend in detection and give subjects olfactory stimulation accurately.
In the mankind, nervi olfactory and nervi trigeminus can produce olfactory stimulation.By OEP, detect discovery, most of abnormal smells from the patient is while excited nervi olfactory and trifacial, is called bimodulus abnormal smells from the patient (bimodal odors); The abnormal smells from the patient that only has minority, as vanillin, phenethanol, hydrogen sulfide only cause that nervi olfactory is excited, carbon dioxide only causes that nervi trigeminus is excited, is called single mode abnormal smells from the patient (unimodal odors).In the olfactory function of studying the happy degree of abnormal smells from the patient detects, the pentyl acetate (Fructus Musae taste) of vanillin (fragrant and sweet taste), phenethanol (Rose Essentielle) and the bimodulus of the conventional single mode of people and other fragrance of a flower, fruital represent happy abnormal smells from the patient, with stench, corrupt class abnormal smells from the patients such as the hydrogen sulfide of single mode and the pyridine of bimodulus, ammonia, represent offending abnormal smells from the patient.Some research discoveries, euosmia mainly activates pyriform lobe and right side socket of the eye frontal convolution, and unhappy abnormal smells from the patient mainly activates corpus amygdaloideum and left side socket of the eye frontal convolution, and some research reports that happy gas mainly causes that left hemisphere activates, unhappy gas is contrary.The appearance of these differences, twofold modularity and the odorousness that may ignore with only considering the happy degree of abnormal smells from the patient abnormal smells from the patient are relevant.
In order to stimulate parkinson patient's olfactory function, be all the olfactory stimulation system that can be used for nuclear magnetic resonance environment that researcher is researched and developed voluntarily, as shown in Figure 1 in the past.
The checkout equipment that these are different, because its plumbing installation that is transported to nasal cavity is often with silica gel or the plastic conduit device of scent of or serious abnormal smells from the patient.This reduces, cannot extract the simple agent Odor stimulation Nao district results of stimulation of smelling by the reliability that makes check result.Meanwhile, uncovered face shield makes the concentration of smelling agent receive dilution in various degree, and the degree that each irritaiting concentration is diluted exists huge diversity.
Defect in all designs, makes the problems such as accurate confirmation by the development process that causes degree accurate not and that cannot decline to patient's olfactory sensation or olfactory sensation to decline above.
summary of the invention
The purpose of this utility model is that the problem existing in order to solve above-mentioned olfactory stimulation system, provides a kind of standardized, utilizes scentless full glass pipe material device patient's nasal cavity to be carried out to the device of olfactory stimulation.
The technical solution of the utility model is, this utility model olfactory stimulation device is by smelling agent accommodation bottle 3, large-scale syringe 1, long glass tubing 4 for mobilizable ventilation, for mobilizable ventilation, short glass tubing 5, large-scale syringe are derived glass tubing 11, are entered and smell the grass tube 12 of agent accommodation bottle, the glass tubing 13 of deriving from smelling agent accommodation bottle, glass valve 6,7, bifurcated pipe, scale 9, base 8 form.Large-scale syringe 1 is fixed on base 8 central authorities, smells agent accommodation bottle 3 and is placed on large-scale syringe 1 side; Large-scale syringe is the cylindrical shape of class, and the both sides of the bottom of syringe next-door neighbour's holder have large-scale syringe from bottom to top to derive glass tubing 11, be connected to be positioned at large-scale syringe other smell agent accommodation bottle; From syringe two bottom sides out, after the glass valve 6 of connection, the other end of glass valve 6 connects the grass tube 12 smell agent accommodation bottle and enters and smell agent accommodation bottle; The opposite side of smelling agent accommodation bottle bottleneck is to smell the glass tubing 13 that agent accommodation bottle is derived.
Mobilizable ventilation is positioned at outside firm banking with short glass tubing 5 with long glass tubing 4 and mobilizable ventilation, for glass pipe movably, both sides are symmetric, and both sides are all comprised of with short glass tubing 5 with long glass tubing 4 and mobilizable ventilation mobilizable ventilation separately.Mobilizable ventilation has a bifurcated pipe with the outlet of long glass tubing 4, for being placed in patient nostril.Bifurcated pipe is " U " shape, in each branch with Miniature switch valve.
Between two floating pipes and floating pipe and bottle outlet pipeline enclosure hose connection by tasteless PEP, every section of long 4cm of flexible pipe, is enclosed within outside the glass pipe of both sides.Mobilizable ventilation is with the main landing ground that connects of short glass tubing 5 to the distance of examinating couch, and mobilizable ventilation is mainly connecting the examinating couch place of entering to the distance in patient nostril with long glass tubing 4.
The scale that the rear of syringe has a thin glass to make, is fixed on the firm banking at syringe rear, and the top of transparent scale is connecting a simple and easy stopwatch, for non-metallic material not affected by magnetic fields is made, inject after gas at every turn, press the switch that makes zero, be easy to make zero.
This utility model has beneficial effect to be, due to this utility model device can more accurately give patient containing other gas smell agent Odor stimulation, so can increase substantially the purity of patient's irriate, thereby improve in detecting, stimulate precision and reliability.Can not only system and carry out on one's own initiative measuring accurately thering is Parkinsonian's olfactory disorder symptom, and can differentiate exactly Stimulation of The Brain districts different in subsequent analysis, stimulation degree etc.Meanwhile, owing to providing, be with graduated scale, can critically adjust the precision of irritant gas amount, examiner operates in magnetic resonance examination chamber, and according to the voice message outside inspection chamber, give patient stimulates in good time, and can give exactly patient stimulates.This utility model device is that tasteless material is made, and can merely give patient and singly plant Odor stimulation.Meanwhile, this device is cheap, can make relatively easily, is beneficial to the unification of different olfactory stimulation devices, is beneficial to unification and the relative analysis of testing result.
This utility model is applicable to when parkinson patient functional MRI (fMRI) detects olfactory function using.
accompanying drawing explanation
Fig. 1 is this utility model olfactory stimulation apparatus structure schematic diagram;
Fig. 2 is bifurcated pipe schematic diagram;
Fig. 3 smells agent accommodation bottle to be connected removable section with conduit;
Fig. 4 is simple and easy stopwatch schematic diagram;
Fig. 5 be between two floating pipes and floating pipe and bottle outlet pipeline enclosure by tasteless hose connection signal;
Fig. 6 is base plate schematic diagram;
Fig. 7 is this utility model embodiment 2 schematic diagrams
Fig. 8 is this utility model embodiment 3 schematic diagrams;
Picture in picture number: the 1st, large-scale syringe; The 2nd, the container part of large-scale syringe; The 3rd, smell agent accommodation bottle; The 4th, mobilizable long glass tubing for ventilation; The 5th, the short glass tubing of mobilizable ventilation; The 6th, glass valve A; The 7th, glass valve B; The 8th, base plate; The 9th, scale; The 11st, large-scale syringe is derived glass tubing; The 12nd, enter the grass tube of smelling agent accommodation bottle; The 13rd, the glass tubing of deriving from smelling agent accommodation bottle.
The specific embodiment
The olfactory stimulation device of this utility model embodiment comprises that at least two are smelt agent accommodation bottle and olfactory sensation bottle fixed part.At least one movable pipe end is placed in parkinson patient nasal cavity, for directly giving parkinson patient, smells agent stimulation.
The present embodiment olfactory stimulation device is by smelling agent accommodation bottle 3, large-scale syringe 1, long glass tubing 4 for mobilizable ventilation, for mobilizable ventilation, short glass tubing 5, large-scale syringe are derived glass tubing 11, are entered and smell the grass tube 12 of agent accommodation bottle, the glass tubing 13 of deriving from smelling agent accommodation bottle, glass valve 6,7, bifurcated pipe, scale 9, base 8 form.
Smell agent accommodation bottle 3 and comprise containing and smell the body of agent solution and the conduit of turnover 12,13, and glass valve 6,7 separately on conducting pipes, also have the opening valve at the body top in whole device outside, for changing, smell agent solution, with glass cover, cover.Glass valve comprises valve body and opening and closing element.
Olfactory sensation bottle fixed part comprises for fixing base and the large-scale syringe for measuring.
Fixing base is a long 20cm, wide 7cm, and the glass blocks of thick 0.5cm as shown in Figure 5, is placed in and smells the place of agent accommodation bottle with the Baltimore groove of 0.1cm on base, with round-shaped meeting at the bottom of bottle, for placing, smells agent accommodation bottle use.
Large-scale syringe is connected in fixing base central authorities, higher than base platform 0.5cm.Large-scale syringe is the cylindrical shape of class, and the radius of round bottom is 5.92cm, cylinder height 19.5cm, and the scale unit of syringe is ml.Corresponding, from 3cm under syringe top, start, numeral is designated as 0,220,440,660,880,1100,1320,1540 from top to bottom.There is grass tube 11 from bottom to top the both sides of bottom next-door neighbour's holder of syringe, are connected to and smell agent accommodation bottle 3.This grass tube diameter internal diameter is 0.5cm, it specifically walk behavior: from syringe two bottom sides out, middle after the glass valve 6 of a connection, tap into into the grass tube of smelling agent accommodation bottle and enter and smell agent accommodation bottle.In the opposite side of smelling agent accommodation bottle bottleneck, by long 3cm, diameter internal diameter is 0.5cm from smelling glass tubing 13 that agent accommodation bottle derives for going out to smell the conduit of agent accommodation bottle traveling.
The piston height overall 3cm of large-scale syringe 1, under comprise 0.1cm the circular glass sheet adapting with piston size, with the plastic cement abnormal smells from the patient of isolated piston farthest.The rubber part height that is piston is 2.9cm, and circular glass sheet thickness is 0.1cm,
The scale that the rear of syringe has a thin glass to make, be fixed on the firm banking at syringe rear, under the 3cm on high 50cm ,Yu top, locate to start to count every 2cm to mark: 0,220,440,660,880,1100,1320,1540,1760, unit is ml.The push rod of syringe is glass cylinder, and diameter 1cm is positioned at the central authorities of scale, high 30.5cm, and the highest point of push rod is extended for to the glass rod of the horizontal shape in both sides, is convenient to hands and holds glass rod tractive.
The top of transparent scale is connecting a simple and easy stopwatch, as shown in Figure 4; For non-metallic material not affected by magnetic fields, make, inject after gas at every turn, press the switch that makes zero, be easy to make zero.
Mobilizable ventilation is positioned at firm banking glass pipe movably outward with glass pipe, and both sides are symmetric, and both sides are all comprised of with 5 two grass tubes of short glass tubing with long glass tubing 4 and mobilizable ventilation mobilizable ventilation separately.Diameter internal diameter is all 0.5cm, a long 100cm, the long 150cm of another root.The outlet of the floating pipe of longer 150cm connects a bifurcated pipe, for being placed in patient nostril.
As shown in Figure 2, bifurcated pipe is " U " shape to bifurcated pipe.Inner side at a distance of 1.5cm, is about 2cm, and spout diameter is 0.5cm, in each branch with Miniature switch valve.
Between two floating pipes and floating pipe and bottle outlet pipeline enclosure hose connection by tasteless PEP, every section of long 4cm of flexible pipe, is enclosed within outside the glass pipe of both sides.Length is that mobilizable ventilation of 100cm mainly connects landing ground to the distance of examinating couch with short glass tubing 5, and mobilizable ventilation that length is 150cm is mainly connecting the examinating couch place of entering to the distance in patient nostril with long glass tubing 4.
The supporting standby attemperator that provides is provided outward two floating pipes, is the sponge foam material of insulation.
Embodiment 1:
Figure 1 shows that the first embodiment of this utility model olfactory stimulation device.The present embodiment olfactory stimulation device comprises that two are smelt agent accommodation bottle.
In order to give the single mode abnormal smells from the patient of the different happy degree of human body, originally executing the odorant agent that routine micro-tapping adopts is vanillin aqueous solution and sodium sulfide solution.As shown in Figure 1, left side is smelt agent accommodation bottle and is filled vanillin aqueous solution, and right side is smelt agent accommodation bottle and filled sodium sulfide solution.
The fixing class chinese cymbidium beany flavour that produces of vanillin aqueous solution, micro-sweet, in this experiment as fragrant, smelling good, happy abnormal smells from the patient.
Sodium sulfide solution produces rotten egg stink, in this experiment as smelly, unpleasant, offending abnormal smells from the patient.
The present embodiment gives patient's olfactory stimulation and refers to when above two kinds of gases suck on a small quantity under the prerequisite of human body nonhazardous reaction, and the flow speed control of two kinds of abnormal smells from the patients and air is in contrast about 1.2l/min.
Although the solute of described sodium sulfide solution is sodium sulfide, the gas producing is hydrogen sulfide, and what give patient's stimulation is the abnormal smells from the patient of the similar rotten egg of hydrogen sulfide gas.Although the neurotoxin that hydrogen sulfide is strong, has intense stimulus effect to mucosa, the hydrogen sulfide gas that sodium sulfide solution produces is just a small amount of gas.The concentration of hydrogen sulfide be take and tested front volunteer and all think that sense of smell is not pungent as normal concentration, a small amount of stimulation of short-term now to health almost without injury.
Action need two people that carry out this olfactory stimulation device coordinate simultaneously.
Before carrying out the operation of this olfactory stimulation device, the time of plastics Chronograph need be stopped being arranged to and each chunk time consistency of tile designs, and can repeatedly move this time period.
Before carrying out the operation of this olfactory stimulation device, need to check the closure of pipeline:
(1) whether the junction of inspection pipeline all connects good.
(2) check the air-tightness that gas pipeline between agent accommodation bottle preceding switch valve is smelt in both sides: screw both sides and smell the switch valve before agent accommodation bottle, firmly to syringe, push away gas simultaneously, when obturation can not be injected if feel, illustrate that the switch valve that smell before agent accommodation bottle both sides is substantially airtight.
(3) check a complete set of gas pipeline air-tightness of a side: open examine one side and smell the switch valve before agent accommodation bottle, syringe is evacuated to after highest point, screw again the 150cm catheter tip of smelling an agent stimulating apparatus side to be detected and smell the switch valve of agent nose conduit bilateral, firmly to syringe, push away gas simultaneously, when obturation can not be injected if feel, illustrate that a complete set of gas pipeline of examine side is substantially airtight.
(4) check a complete set of gas pipeline air-tightness of a side: use the same method and detect the air-tightness of a complete set of gas pipeline of opposite side.
Before giving the stimulation of human body euosmia, need screw the supravasal switch valve that right side passes into body.
Before carrying out the operation of this olfactory stimulation device, need open the corresponding switch valve that agent stimulating apparatus 150cm catheter tip is smelt agent nose conduit one side or bilateral of smelling.
In carrying out the operation Qian,Xu Xiang both sides 100cm of this olfactory stimulation device and the pipeline of 150cm, inject separately olfactory stimulation gas separately, deaeration, prepares for giving patient's stimulation.
To fragrance, smelling the concrete operations that agent marginal not enters fragrance gas is:
(1) to syringe, inflate: agent accommodation bottle is smelt in right side and from syringe bottom, detachably dismantle, the pull bar of syringe is pulled to after highest point.
(2) give a side gas pipeline ventilation: screw right side and smell the switch valve before agent accommodation bottle, the piston of syringe is slowly evenly pushed into lowest part.
(3) fully take a breath repeatedly to a side gas pipeline: Hou Jiang smells on right side agent accommodation bottle and detachably dismantles from syringe bottom, and the piston of device to be injected is pulled to after highest point.Install again right side and smell agent accommodation bottle, also will guarantee that right side smells switch valve before agent accommodation bottle in screwing state simultaneously, the piston of syringe is slowly evenly pushed into lowest part.
(4) stop pushing away gas condition: so repeatedly several times, until nose catheter opening place, can smell and when vanillin is smelt agent abnormal smells from the patient, stop injecting gas, screw and smell the switch valve that agent stimulating apparatus left side 150cm catheter tip is smelt agent nose conduit bilateral, and left side vanillin fragrance is smelt the switch valve before agent accommodation bottle.
(5) give the ventilation of opposite side gas pipeline: left side vanillin is smelt to agent accommodation bottle and from syringe bottom, detachably dismantle, the piston of device to be injected is pulled to after highest point, uses the method repetitive operation, gives the gas that right side pipeline injects sodium sulfide abnormal smells from the patient.
(6) ending step: finally screw and smell the switch valve that agent stimulating apparatus left side 150cm catheter tip is smelt agent nose conduit bilateral, and right side sodium sulfide stink is smelt the switch valve before agent accommodation bottle, required Odor stimulation in starting to test.
In the operation of this olfactory stimulation device, personnel in inspection chamber receive in broadcast after the information from personnel in the operating room outside inspection chamber, open plastics Chronograph, start timing, start to coordinate time of continuous running to carry out the operation of this olfactory stimulation device.After equably injector push-rod top upper limb being pushed into scale first scale 220ml place for the first time in first circulation time section, stop, representing to have given the micro-tapping of patient 220ml.Wait for that plastics Chronograph has moved after second time period circulation repeatedly, then stop after equably syringe being pushed into second scale 440ml place, represent to give again the micro-tapping of patient 220ml, altogether give the micro-tapping of patient 440ml.
From then on repeatedly 8 times, until given patient 1760ml gas.
The scale of described scale and the scale on syringe are completely equidistant, scale are obviously marked on the top scale of syringe eminence, are can observing time during for the ease of operation, also can observe and inject gas flow, are so more conducive to control the speed of injecting.
Embodiment 2:
The olfactory stimulation device of the second embodiment of the present utility model as shown in Figure 7, injects a kind of agent solution of smelling as only giving a kind of method of gas in described olfactory sensation experimentation, can give to smell 3 of agent accommodation bottles.
When giving patient's olfactory stimulation, need equally before experiment by step as above successively detect a whole set of pipeline air-tightness, to pipeline, change to the abnormal smells from the patient of irritant gas, wait tone starts executable operations etc.
Embodiment 3:
The olfactory stimulation device of the 3rd embodiment of the present utility model as shown in Figure 8, as needing to give the method for several different gases in described olfactory sensation experimentation, can be given to smell and in agent accommodation bottle 3, inject respectively several agent solutions of smelling.Then by the step of embodiment 1, operate.

Claims (7)

1. Parkinsonian's magnetic resonance detects olfactory stimulation device, it is characterized in that, described device is by smelling agent accommodation bottle (3), large-scale syringe (1), long glass tubing for mobilizable ventilation (4), short glass tubing (5) for mobilizable ventilation, large-scale syringe are derived glass tubing (11), are entered and smell the grass tube (12) of agent accommodation bottle, the glass tubing (13) of deriving from smelling agent accommodation bottle, glass valve (6), (7), bifurcated pipe, scale (9), base (8) form; Large-scale syringe (1) is fixed on base (8) central authorities, smells agent accommodation bottle (3) and is placed on large-scale syringe (1) side; The large-scale syringe of described large-scale syringe two bottom sides is derived grass tube (12) that glass tubing (11) smells agent accommodation bottle by glass valve (6) connection and is entered and smell agent accommodation bottle; The opposite side of smelling agent accommodation bottle bottleneck is provided with smells the glass tubing (13) that agent accommodation bottle is derived, mobilizable for ventilation long glass tubing (4) or for mobilizable ventilation short glass tubing (5) by elbow, connect valve (7), the other end of valve (7) connects smells the glass tubing (13) that agent accommodation bottle is derived; Mobilizable for ventilation the other end of long glass tubing (4) connect bifurcated pipe.
2. a kind of Parkinsonian's magnetic resonance according to claim 1 detects olfactory stimulation device, it is characterized in that, described large-scale syringe (1) is the cylindrical shape of class, and there is outlet that can mounting glass conduit the both sides of the next-door neighbour bottom surface, bottom of large-scale syringe; The scale (9) that the rear of large-scale syringe (1) has a thin glass to make, the firm banking (8) that is fixed on large-scale syringe (1) rear is upper, and the top of transparent scale (9) is connecting a simple and easy stopwatch.
3. a kind of Parkinsonian's magnetic resonance according to claim 1 detects olfactory stimulation device, it is characterized in that, described in smell agent accommodation bottle (3) bottleneck and insert to enter and smell the grass tube (12) of agent accommodation bottle and the glass tubing (13) of deriving from smelling agent accommodation bottle; Described body top of smelling agent accommodation bottle (3) outside is provided with for changing smells agent solution opening valve, covers at ordinary times with glass cover.
4. a kind of Parkinsonian's magnetic resonance according to claim 1 detects olfactory stimulation device, it is characterized in that, the piston of described large-scale syringe (1) comprises circular glass sheet and the rubber part adapting with piston size, and rubber height is 2.9cm, and circular glass sheet thickness is 0.1cm.
5. a kind of Parkinsonian's magnetic resonance according to claim 1 detects olfactory stimulation device, it is characterized in that, described bifurcated pipe is " U " shape; In each branch with Miniature switch valve.
6. a kind of Parkinsonian's magnetic resonance according to claim 1 detects olfactory stimulation device, it is characterized in that, described mobilizable for ventilation long glass tubing (4) and mobilizable ventilation with between (5) two floating pipes of short glass tubing and floating pipe and bottle outlet pipeline enclosure hose connection by tasteless PEP, every section of long 4cm of flexible pipe, is enclosed within outside the glass pipe of both sides.
7. a kind of Parkinsonian's magnetic resonance according to claim 1 detects olfactory stimulation device, it is characterized in that described glass valve comprises valve body and opening and closing element.
CN201320460699.0U 2013-07-31 2013-07-31 Olfaction stimulus device for PD (Parkinson's Disease) patient magnetic resonance detection Expired - Fee Related CN203388854U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113647915A (en) * 2021-09-25 2021-11-16 天津中科安迪医学检验实验室有限公司 Autism olfaction anomaly detection device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113647915A (en) * 2021-09-25 2021-11-16 天津中科安迪医学检验实验室有限公司 Autism olfaction anomaly detection device

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Inventor after: Deng Xia

Inventor before: Xu Rensi

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