CN203337669U - Rapid joint inspection test paper card for pre S1 antigen and pre S2 antigen of hepatitis B virus - Google Patents
Rapid joint inspection test paper card for pre S1 antigen and pre S2 antigen of hepatitis B virus Download PDFInfo
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- CN203337669U CN203337669U CN201320319150XU CN201320319150U CN203337669U CN 203337669 U CN203337669 U CN 203337669U CN 201320319150X U CN201320319150X U CN 201320319150XU CN 201320319150 U CN201320319150 U CN 201320319150U CN 203337669 U CN203337669 U CN 203337669U
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- antigen
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- sample pad
- nitrocellulose filter
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Abstract
The utility model relates to a rapid joint inspection test paper card for a pre S1 antigen and a pre S2 antigen of hepatitis B virus. The rapid joint inspection test paper card comprises a card box and a test paper strip, wherein the test paper strip comprises a sample pad, colloidal gold pads, nitrocellulose membranes, absorbent paper, and a PVC (poly vinyl chloride) bottom plate, the sample pad is stuck in the middle of the PVC bottom plate, the colloidal gold pads, the nitrocellulose membranes and absorbent paper are sequentially and symmetrically arranged at two sides of the sample pad, the ends of the sample pad, the colloidal gold pads, the nitrocellulose membranes and the absorbent paper are sequentially overlapped, the nitrocellulose membrane at one side is provided with a detection line made of a single clone antibody coated with anti-pre S1 and a quality control line made of a coated recombined hepatitis B surface antigen, and the nitrocellulose membrane at the other side is provided with the detection line made of a single clone antibody coated with anti-pre S2 and the quality control line made of a coated recombined hepatitis B surface antigen. The rapid joint inspection test paper card has the advantages of being rapid in detection, simple in operation, accurate in result, and vivid and visual, and having higher specificity and sensitivity, and improves the quality of the product.
Description
Technical field
The utility model relates to test card, is specifically related to a kind of hepatitis B virus pro-S 1 and preS 2 antigen fast joint inspection test card.
Background technology
At present, pre S 1 antigen at virus infections, assemble, copy and stimulate body to produce the aspect such as immune response and play a very important role.PreS 2 antigen can reflect copying of hepatitis type B virus and judging prognosis situation sensitively, especially can reflect whether the hepatitis B patient of HBeAg feminine gender has virus replication.Molecular hyridization, the method length consuming time such as PCR, ELISA that detect for these two kinds of antigens at present, program is many, influence factor is many.Therefore need on different test cards, drip respectively sample, still, due to time, the dripping quantity difference of twice sample, easily cause the detection of test card of low quality.
The utility model content
Technical problem to be solved in the utility model is to provide a kind of hepatitis B virus pro-S 1 and preS 2 antigen fast joint inspection test card, and it once drips sample can be simultaneously to hepatitis B virus pro-S 1 and preS 2 antigen fast detecting, thereby eliminates defect in the above-mentioned background technology.
For solving the problems of the technologies described above, the technical solution of the utility model is:
A kind of hepatitis B virus pro-S 1 and preS 2 antigen fast joint inspection test card, comprise cartridge and be installed in described cartridge in order to detect the test strips of pre-S 1 antigens of hepatitis B viruses and preS 2 antigen, described test strips comprises sample pad, gold mark pad, nitrocellulose filter, thieving paper and PVC base plate, described sample pad is pasted on the middle of described PVC base plate, and the two ends symmetry sequentially is arranged with gold mark pad, nitrocellulose filter and thieving paper, the end of described sample pad, gold mark pad, nitrocellulose filter and thieving paper sequentially overlaps;
Wherein on the nitrocellulose filter of a side, be provided with detection line and the coated recombination hepatitis B surface antigen that coated anti-front S1 monoclonal antibody makes and make nature controlling line;
Be provided with detection line and the coated recombination hepatitis B surface antigen that coated anti-front S2 monoclonal antibody makes on the nitrocellulose filter of opposite side and make nature controlling line;
Described cartridge comprises box body, and the middle of described box body is provided with the sample hole adapted in described sample pad position, and the both sides in described sample hole all are symmetrical arranged viewing mask, and described viewing mask is corresponding one by one with the cellulose nitrate film location.
In the utility model, described gold mark pad is the fiberglass packing that is coated with the anti-HBs polyclonal antibody of colloid gold label.
Owing to having adopted technique scheme, the beneficial effects of the utility model are:
The utility model has adopted symmetrical structure, once drip sample and can detect pre-S 1 antigens of hepatitis B viruses and preS 2 antigen simultaneously, and avoided because drip the detection quality problems that a sample asynchronism(-nization), consumption difference bring, have detect quick, simple to operate, result is accurate, visual in image, have than advantages such as high specific and sensitivity, improved the quality of this product.
The accompanying drawing explanation
Fig. 1 is the structural representation of the utility model test strips;
The structural representation that Fig. 2 is the utility model cartridge;
In figure: 1. test strips, 2. cartridge;
11. sample pad, 12.PVC base plate, 13. first gold medal mark pads, 14. first nitrocellulose filters, 15. the first thieving paper, 16. the second gold medal mark pad, 17. second nitrocellulose filters, 18. second thieving papers, 141. the detection line that coated anti-front S1 monoclonal antibody is made, 142. the first nature controlling line, the detection line that 171. coated anti-front S2 monoclonal antibodies are made, 172. second nature controlling lines;
21. box body, 22. sample holes, 23. viewing masks.
Embodiment
For technological means, creation characteristic that the utility model is realized, reach purpose and effect is easy to understand, below in conjunction with concrete diagram, further set forth the utility model.
As depicted in figs. 1 and 2, a kind of hepatitis B virus pro-S 1 and preS 2 antigen fast joint inspection test card, comprise cartridge 2 and be installed on the test strips 1 in order to detect pre-S 1 antigens of hepatitis B viruses and preS 2 antigen in described cartridge 2, described test strips 1 comprises sample pad 11, gold mark pad, nitrocellulose filter, thieving paper and PVC base plate 12, described sample pad 11 is pasted on the middle of described PVC base plate 12, two ends adopt symmetrical structure, one end of sample pad 11 sequentially is placed with the first gold medal mark pad 13, the first nitrocellulose filter 14 and the first thieving paper 15, and the first gold medal mark pad 13, the end of the first nitrocellulose filter 14 and the first thieving paper 15 sequentially overlaps, the other end sequentially is placed with the second gold medal mark pad 16, the second nitrocellulose filter 17 and the second thieving paper 18, and the end of the second gold medal mark pad 16, the second nitrocellulose filter 17 and the second thieving paper 18 sequentially overlaps.In addition, be provided with detection line 141 and the coated recombination hepatitis B surface antigen that coated anti-front S1 monoclonal antibody makes on the first nitrocellulose filter 14 and make the first nature controlling line 142; Be provided with detection line 171 and the coated recombination hepatitis B surface antigen that coated anti-front S2 monoclonal antibody makes on the second nitrocellulose filter 17 and make the second nature controlling line 172.
In the present embodiment, described cartridge 2 comprises box body 21, the middle of described box body 21 is provided with the sample hole 22 adapted in described sample pad 11 positions, and 22 both sides, described sample hole all are symmetrical arranged viewing mask 23, and described viewing mask 23 is corresponding one by one with the cellulose nitrate film location.
In the present embodiment, the all-glass paper that described gold mark pad is the anti-HBs polyclonal antibody coating of coated colloid gold label.
The utility model is not limited to above-mentioned embodiment, and all are based on technical conceive of the present utility model, and the structural improvement of having done, all fall among protection domain of the present utility model.
Claims (2)
1. a hepatitis B virus pro-S 1 and preS 2 antigen fast joint inspection test card, comprise cartridge and be installed in described cartridge in order to detect the test strips of pre-S 1 antigens of hepatitis B viruses and preS 2 antigen, it is characterized in that: described test strips comprises sample pad, gold mark pad, nitrocellulose filter, thieving paper and PVC base plate, described sample pad is pasted on the middle of described PVC base plate, and the two ends symmetry sequentially is arranged with gold mark pad, nitrocellulose filter and thieving paper, the end of described sample pad, gold mark pad, nitrocellulose filter and thieving paper sequentially overlaps; Wherein on the nitrocellulose filter of a side, be provided with detection line and the coated recombination hepatitis B surface antigen that coated anti-front S1 monoclonal antibody makes and make nature controlling line; Be provided with detection line and the coated recombination hepatitis B surface antigen that coated anti-front S2 monoclonal antibody makes on the nitrocellulose filter of opposite side and make nature controlling line; Described cartridge comprises box body, and the middle of described box body is provided with the sample hole adapted in described sample pad position, and the both sides in described sample hole all are symmetrical arranged viewing mask, and described viewing mask is corresponding one by one with the cellulose nitrate film location.
2. a kind of hepatitis B virus pro-S 1 as claimed in claim 1 and preS 2 antigen fast joint inspection test card, is characterized in that: the described golden fiberglass packing that pads the anti-HBs polyclonal antibody for being coated with colloid gold label of marking.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320319150XU CN203337669U (en) | 2013-06-04 | 2013-06-04 | Rapid joint inspection test paper card for pre S1 antigen and pre S2 antigen of hepatitis B virus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320319150XU CN203337669U (en) | 2013-06-04 | 2013-06-04 | Rapid joint inspection test paper card for pre S1 antigen and pre S2 antigen of hepatitis B virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203337669U true CN203337669U (en) | 2013-12-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320319150XU Expired - Fee Related CN203337669U (en) | 2013-06-04 | 2013-06-04 | Rapid joint inspection test paper card for pre S1 antigen and pre S2 antigen of hepatitis B virus |
Country Status (1)
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| CN (1) | CN203337669U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108351355A (en) * | 2015-08-27 | 2018-07-31 | 奎多公司 | There are two the immunoassay test devices that fluid flow path is used to detect and distinguish two or more analytes for tool |
| CN111381049A (en) * | 2020-03-30 | 2020-07-07 | 天津纽赛生物技术有限公司 | Serology type detection test paper and detection method for rapid new coronavirus antibody |
| CN112557661A (en) * | 2020-10-31 | 2021-03-26 | 上海海洋大学 | Magnetic immunochromatographic test strip and method for rapidly detecting pre-S2 antigen of hepatitis B virus |
-
2013
- 2013-06-04 CN CN201320319150XU patent/CN203337669U/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108351355A (en) * | 2015-08-27 | 2018-07-31 | 奎多公司 | There are two the immunoassay test devices that fluid flow path is used to detect and distinguish two or more analytes for tool |
| US11131670B2 (en) | 2015-08-27 | 2021-09-28 | Quidel Corporation | Immunoassay test device with two fluid flow paths for detection and differentiation of two or more analytes |
| CN113740533A (en) * | 2015-08-27 | 2021-12-03 | 奎多公司 | Immunoassay test device having two fluid flow paths for detecting and distinguishing between two or more analytes |
| US11846637B2 (en) | 2015-08-27 | 2023-12-19 | Quidel Corporation | Immunoassay test device with two fluid flow paths for detection and differentiation of two or more analytes |
| CN111381049A (en) * | 2020-03-30 | 2020-07-07 | 天津纽赛生物技术有限公司 | Serology type detection test paper and detection method for rapid new coronavirus antibody |
| CN112557661A (en) * | 2020-10-31 | 2021-03-26 | 上海海洋大学 | Magnetic immunochromatographic test strip and method for rapidly detecting pre-S2 antigen of hepatitis B virus |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131211 Termination date: 20210604 |