CN203231968U - Optical-fiber type small-sized gold-labeled immunochromatography test paper detector - Google Patents
Optical-fiber type small-sized gold-labeled immunochromatography test paper detector Download PDFInfo
- Publication number
- CN203231968U CN203231968U CN 201320295195 CN201320295195U CN203231968U CN 203231968 U CN203231968 U CN 203231968U CN 201320295195 CN201320295195 CN 201320295195 CN 201320295195 U CN201320295195 U CN 201320295195U CN 203231968 U CN203231968 U CN 203231968U
- Authority
- CN
- China
- Prior art keywords
- optical fiber
- optical
- test paper
- type small
- paper detector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Abstract
The utility model provides an optical-fiber type small-sized gold-labeled immunochromatography test paper detector. The optical-fiber type small-sized gold-labeled immunochromatography test paper detector comprises two groups of excitation light sources (1 and 2), two photodiodes (3 and 4), a processor and a display module, wherein each group of excitation light source comprises a high-brightness light emitting diode (5), a focusing device (6) and an outgoing optical fiber (7), each excitation light source and the corresponding photodiode form a detection loop, the detection loops are respectively used for detecting the color and gray levels of a quality control line (9) and a detection line (10) of a colloidal gold test strip, and the processor is used for analyzing electric signals output from the photodiodes and then outputting results to the display module to be presented to users. The optical fibers are taken as outgoing light sources of the optical-fiber type small-sized gold-labeled immunochromatography test paper detector, and thus the optical-fiber type small-sized gold-labeled immunochromatography test paper detector has the advantages of small size, convenience in carry and low cost.
Description
Technical field
The utility model relates to colloidal gold strip detecting instrument field, is specifically related to a kind of optical fiber type small size gold-marking immunity chromatographic test paper detector.
Background technology
Immuno-gold labeling technology (immunogold labeling technique, ILT) be after the initial stage eighties 19th century, fluorescence immunoassay mark immune labeled continue enzyme, the radioactive isotope immune labeled three big labelling techniques, the novel solid phase labelling immunoassay that grows up.Have easy, rapid, accurate, high specificity, sensitivity height, pollution-free, false positive rate is low etc. advantage.The ultimate principle of colloidal gold immunity chromatography is: by the capillary siphoning effect, make sample and the colloid gold label thing that is sprayed on the glass fibre mix at nitrocellulose membrane mobile, if contain antigen (or antibody) in the sample, antibody (or antigen) combination with colloid gold label, diffuse on the film detection zone again with unlabelled antibody (or antigen) combination, form gold mark antigen antibody complex, be trapped on the detection line and colour developing, can obtain testing result intuitively.
Two lines are generally arranged, detection line (being called for short the T line) and control line (being called for short the C line) on the colloidal gold strip.General bag quilt is another specific antibody of determinand on the T line, and on the C line general bag quilt be the antibody of the acceptor that colloid gold label is crossed on the gold-marking binding pad.Whether the C line is effective for detection of this test, be quite look redness or the purple of collaurum if do not observe color on the line, then represent this test invalidation, the result on the line is inadvisable, if observe color on the meaningless line, then come result of determination according to the color on the T line.
The colloidal gold immunochromatographimethod technology needing to be mainly used in the occasion of qualitative detection.When the concentration of sample in the solution to be checked surpasses certain scope, apparent in view change color can occur, otherwise then not have.This technology particularly suitable has in serum analysis, the urine and does not have the unusual material that raises in the middle of the qualitative monitoring of disease, the content of HCG etc. in urine when for example conceived.Simply whether to surpass the positive boundary of the normal reference value upper limit, testing result is for being or not being this two-value relation for this method.
Progress along with production technology, the quality control of the NC film in the colloidal gold strip is more and more stricter, the manufacturers of a lot of specialties (as Kinma-tic Automation company etc.) provide accurate liquid feeding, cutting and assembling equipment, but also the production line of a robotization complete set is provided, therefore under the condition of carrying out strict quality control, can produce immune colloid gold gold diafiltration kit and the colloidal gold immunochromatographimethod test-strips of character basically identical.The sample that has joined when having guaranteed each detect substantially can and gold mark bond mix the homogeneity that advances on the NC film and the consistance of speed, make the shade according to the T line come the concentration of interpretation sample to be called possibility.
The naked eyes interpretation mainly is to compare with standard color comparison card, and it is slow to have a detection speed, the distinct disadvantage that automaticity is low.And testing staff's subjectivity is big, can't guarantee that testing result is safe and effective always, and error rate is big.
Summary of the invention
The purpose of this utility model is to provide a kind of optical fiber type small size gold-marking immunity chromatographic test paper detector, adopts optical fiber as the outgoing light source, has the advantage that volume is little, easy to carry, cost is low.
The optical fiber type small size gold-marking immunity chromatographic test paper detector that the utility model provides is made up of two groups of excitation sources (1 and 2), two photodiodes (3 and 4), processor and display module.Every group of excitation source is made up of high brightness LED (5), focalizer (6) and outgoing optical fiber (7).
Two groups of excitation sources are formed a detection circuit with a photodiode separately, respectively the nature controlling line (9) of colloidal gold strip and the color gray scale of detection line (10) are surveyed.The light that excitation source (1) sends is mapped to the nature controlling line (9) of colloidal gold strip by outgoing optical fiber, is received by photodiode (3) after launching.The light that excitation source (2) sends is mapped to the detection line (10) of colloidal gold strip by outgoing optical fiber, is received by photodiode (4) after launching.Photodiode (3 and 4) is responsible for light signal is converted to electric signal, then electric signal is transferred to processor analysis.Because there are absorbing phenomenon in nature controlling line (9) and the detection line (10) of colloidal gold strip to the light that excitation source sends, the degree of light absorption is relevant with the color depth of test strips nature controlling line (9) and detection line (10), so by analyzing the electric signal of photodiode output, just can interpretation add the concentration of the sample liquid that colloidal gold strip checks.
Processor outputs to display module with the result and presents to the user after electric signal is analyzed.
Description of drawings
Accompanying drawing is the structural drawing of optical fiber type small size gold-marking immunity chromatographic test paper detector.
Embodiment
Describe embodiment of the present utility model in detail below in conjunction with accompanying drawing:
The optical fiber type small size gold-marking immunity chromatographic test paper detector that the utility model provides is made up of two groups of excitation sources (1 and 2), two photodiodes (3 and 4), processor and display module.
Every group of excitation source is made up of high brightness LED (5), focalizer (6) and outgoing optical fiber (7).The light that high brightness LED (5) sends is injected focalizer (6), and focalizer (6) focuses on light beam on the outer face of outgoing optical fiber (7), and light beam penetrates from the outer face of outgoing optical fiber (7) other end then.
8 is colloidal gold strip to be detected among the figure, and 9 is the nature controlling line of colloidal gold strip, and 10 is the detection line of colloidal gold strip.Nature controlling line (9) shows when color is arranged that the result of this detection is effective, otherwise the result lost efficacy, and generally is owing to reasons such as test strips are expired.The shade of detection line (10) shows the concentration that is added in the sample liquid on the colloidal gold strip.Two groups of excitation sources are formed a detection circuit with a photodiode separately, respectively the nature controlling line (9) of colloidal gold strip and the color gray scale of detection line (10) are surveyed.The light that excitation source (1) sends is mapped to the nature controlling line (9) of colloidal gold strip by outgoing optical fiber, is received by photodiode (3) after reflection.The light that excitation source (2) sends is mapped to the detection line (10) of colloidal gold strip by outgoing optical fiber, is received by photodiode (4) after reflection.The light on and off of excitation source (1 and 2) are subject to processing device control.
Photodiode (3 and 4) is responsible for light signal is converted to electric signal, then electric signal is transferred to processor analysis.Because there are absorbing phenomenon in nature controlling line (9) and the detection line (10) of colloidal gold strip to the light that excitation source sends, the degree of light absorption is relevant with the color depth of test strips nature controlling line (9) and detection line (10), so by analyzing the electric signal of photodiode output, just can interpretation add the concentration of the sample liquid that colloidal gold strip checks.Selected processor comprises two-way AD converting unit, can convert the electric signal of photodiode output to digital signal, can carry out arithmetic operation to it then.
Processor carries out analyzing and processing to the electric signal of photodiode output, obtains the result and outputs to display module.In order to reduce cost, display module adopts the lattice lcd screen.
Claims (2)
1. an optical fiber type small size gold-marking immunity chromatographic test paper detector is made up of two groups of excitation sources (1,2), two photodiodes (3,4), processor and display module; Described excitation source is made up of high brightness LED (5), focalizer (6) and outgoing optical fiber (7); It is characterized in that the light that described high brightness LED (5) sends injects focalizer (6), focalizer (6) focuses on light beam on the outer face of outgoing optical fiber (7), and light beam penetrates from the outer face of outgoing optical fiber (7) other end then; The light that excitation source (1) sends is mapped to the nature controlling line (9) of colloidal gold strip by outgoing optical fiber, is received by photodiode (3) after reflection; The light that excitation source (2) sends is mapped to the detection line (10) of colloidal gold strip by outgoing optical fiber, is received by photodiode (4) after reflection; Photodiode (3,4) receiving optical signals converts electric signal to, then electric signal is transferred to processor, and processor shows result at display module.
2. a kind of optical fiber type small size gold-marking immunity chromatographic test paper detector as claimed in claim 1 is characterized in that described display module adopts the lattice lcd screen.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320295195 CN203231968U (en) | 2013-05-24 | 2013-05-24 | Optical-fiber type small-sized gold-labeled immunochromatography test paper detector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320295195 CN203231968U (en) | 2013-05-24 | 2013-05-24 | Optical-fiber type small-sized gold-labeled immunochromatography test paper detector |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203231968U true CN203231968U (en) | 2013-10-09 |
Family
ID=49288088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201320295195 Expired - Fee Related CN203231968U (en) | 2013-05-24 | 2013-05-24 | Optical-fiber type small-sized gold-labeled immunochromatography test paper detector |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203231968U (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104298979A (en) * | 2014-10-31 | 2015-01-21 | 广州万孚生物技术股份有限公司 | Device and method for identifying biological test paper |
| CN105137093A (en) * | 2015-07-24 | 2015-12-09 | 天津起跑线生物信息技术有限公司 | Method for early warning of ovulation period |
| CN107576584A (en) * | 2017-09-20 | 2018-01-12 | 天津瑞泽分析仪器有限公司 | A kind of fruit quality comprehensive detection analyzer |
| CN108469525A (en) * | 2018-06-30 | 2018-08-31 | 武汉生之源生物科技股份有限公司 | A kind of fluoroimmunoassay device and method |
| CN112666095A (en) * | 2020-12-29 | 2021-04-16 | 上海理工大学 | Urine composition analysis device based on color mark sensor |
| CN117054410A (en) * | 2023-10-12 | 2023-11-14 | 乐福思健康产业股份公司 | Detection method of colloidal gold immunochromatography analyzer |
-
2013
- 2013-05-24 CN CN 201320295195 patent/CN203231968U/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104298979A (en) * | 2014-10-31 | 2015-01-21 | 广州万孚生物技术股份有限公司 | Device and method for identifying biological test paper |
| CN104298979B (en) * | 2014-10-31 | 2017-10-17 | 广州万孚生物技术股份有限公司 | The identifying device and method of a kind of biological test paper |
| CN105137093A (en) * | 2015-07-24 | 2015-12-09 | 天津起跑线生物信息技术有限公司 | Method for early warning of ovulation period |
| CN107576584A (en) * | 2017-09-20 | 2018-01-12 | 天津瑞泽分析仪器有限公司 | A kind of fruit quality comprehensive detection analyzer |
| CN108469525A (en) * | 2018-06-30 | 2018-08-31 | 武汉生之源生物科技股份有限公司 | A kind of fluoroimmunoassay device and method |
| CN112666095A (en) * | 2020-12-29 | 2021-04-16 | 上海理工大学 | Urine composition analysis device based on color mark sensor |
| CN117054410A (en) * | 2023-10-12 | 2023-11-14 | 乐福思健康产业股份公司 | Detection method of colloidal gold immunochromatography analyzer |
| CN117054410B (en) * | 2023-10-12 | 2024-02-06 | 乐福思健康产业股份公司 | Detection method of colloidal gold immunochromatography analyzer |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN203231968U (en) | Optical-fiber type small-sized gold-labeled immunochromatography test paper detector | |
| CN201051102Y (en) | Quick tester for gold colloid | |
| CN103344633A (en) | Chemiluminiscence substrate liquid of alkaline phosphatase | |
| CN101545864A (en) | Optical analysis reading device | |
| CN102128830B (en) | Immunochromatographic test paper strip color signal quantitative detector | |
| CN201210144Y (en) | Optical analysis reading device | |
| CN102095497B (en) | Pinhole imaging-based quantitative detector for color development signal of immunochromatography detection test strip | |
| CN207964840U (en) | The food safety comprehensive analytical equipment of fluorescence immune chromatography quantitative check can be achieved | |
| CN104406941A (en) | Multifunctional food safety comprehensive detector | |
| CN205027755U (en) | Multi -functional determine module box on immunoassay appearance | |
| CN103499699A (en) | Fluorescent microsphere immunochromatographic assay quantitative detector by combination of internet-of-things data transmission system | |
| CN103743897A (en) | Multi-item mixed fluorescence immune reaction based spectroscopic analysis method | |
| CN103499687A (en) | Colloidal gold immunochromatographic assay quantitative detector by combination of internet-of-things data transmission system | |
| CN105974108A (en) | Immunochromatography detection system and detection method | |
| CN101762565A (en) | Parallel fiber-grating type remote sensing system for a plurality of polluted gases | |
| CN104181295B (en) | A kind of multi-thread colloidal gold strip quantitative test image processing method | |
| CN201408166Y (en) | Submerged rapid water quality analyzer | |
| CN208580108U (en) | A kind of anti-Miao Leguan hormone immunity chromatography quantitative testing test paper item | |
| CN207798846U (en) | A kind of whole blood immunity detection device | |
| CN206489163U (en) | A kind of grating type ELIASA of hospital laboratory | |
| CN2490584Y (en) | Immune magnet microsphere fluorescent fiber-optical flow analyser | |
| CN205679617U (en) | A kind of Nanosurface plasma resonance sensor microwell plate | |
| CN111650378A (en) | High-sensitivity wide-detection-range fluorescence immunochromatographic test paper | |
| CN205157437U (en) | Test paper strip fluorescence biological detection system | |
| CN203310752U (en) | Aflatoxin quantitative detector |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131009 Termination date: 20150524 |
|
| EXPY | Termination of patent right or utility model |