CN203133091U - Body fluid ingredient detector - Google Patents

Body fluid ingredient detector Download PDF

Info

Publication number
CN203133091U
CN203133091U CN 201320068524 CN201320068524U CN203133091U CN 203133091 U CN203133091 U CN 203133091U CN 201320068524 CN201320068524 CN 201320068524 CN 201320068524 U CN201320068524 U CN 201320068524U CN 203133091 U CN203133091 U CN 203133091U
Authority
CN
China
Prior art keywords
analyte
mentioned
plate
supply port
stream
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN 201320068524
Other languages
Chinese (zh)
Inventor
臼井务
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aikus Corp
Original Assignee
TTM Co Ltd Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TTM Co Ltd Japan filed Critical TTM Co Ltd Japan
Application granted granted Critical
Publication of CN203133091U publication Critical patent/CN203133091U/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Landscapes

  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The utility model provides a body fluid ingredient detector. The body fluid ingredient detector can be used for authentically transferring analyte by simple push operations and can be used for authentically detecting the analyte; besides, the running cost is low. The body fluid ingredient detector comprises an analyte supply port (11) for supplying the analyte to the internal part, a detecting chamber (7) for detecting the analyte, a flow path (8) for communicating the analyte supply port (11) with the detecting chamber (7), and a blood cell separating membrane (6) for removing blood cells from the analyte supplied to the analyte supply port (11) and then supplying to the flow path; a plate (3) provided with a through hole (71) and a through groove (83) and made of a waterproof and breathable porous material is sandwiched by two waterproof and airtight plates (2, 4) along the thickness direction to form an overlapped plate (20), and the detecting chamber (8) and the flow path (8) are arranged on the overlapped plate (20); and a substrate (1) adhered with the overlapped plate (20) is provided with the analyte supply port (11) and the blood cell separating membrane (6).

Description

The inspection utensil of body fluid components
Technical field
The utility model relates to the body fluid components of the biology inspection utensil measured such as glucose, neutral fat, uric acid, cholesterol for example.
Background technology
In the past, as this inspection utensil, the known inspection utensil that is recorded in patent documentation 1.As its content, possess analyte supply port and pump connector, between them, be provided with analyte process chamber and measuring cell through stream with connected state.So the analyte that will be fed into the analyte supply port by the driving of the pump that has been connected with connector is transferred to measuring cell from the analyte process chamber, carries out the mensuration of analyte in this measuring cell.
Yet above-mentioned inspection utensil is owing to use pump as the transfer device of analyte, so it is difficult that the control when transferring analyte becomes, in addition, unitary construction complicates, and cost of products improves, and operating cost also improves.
The prior art document
Patent documentation
Patent documentation 1: Japanese kokai publication hei 8-114539 communique
The utility model content
Utility model problem to be solved
Therefore, the purpose of this utility model is to provide a kind of inspection utensil of body fluid components, the inspection utensil of this body fluid components does not need the mechanical force of pump etc., just can positively carry out the handover of analyte by simple bulldozing operation, can carry out certain mensuration of analyte, and operating cost is also cheap.
Be used for solving the technological means of problem
In order to achieve the above object, the inspection utensil of body fluid components of the present utility model is characterised in that: possess the analyte supply port to inner supply analysis thing, carry out the measuring cell of the mensuration of above-mentioned analyte, be communicated with the stream of above-mentioned analyte supply port and said determination chamber and from the above-mentioned analyte that has supplied to above-mentioned analyte supply port blood cell removed the blood cell diffusion barrier that the back is supplied with to above-mentioned stream; By two watertightnesses and airproof plate thickness direction be provided with through hole and through slot by watertightness and have plate holder that the porous material of gas penetration potential constitutes and go into and constitute plywood, be provided with said determination chamber and above-mentioned stream at this plywood; The said determination chamber is by above-mentioned through hole and above-mentioned two watertightnesses and the division of airproof plate, above-mentioned stream is divided by above-mentioned through slot and above-mentioned two watertightnesses and airproof plate, with above-mentioned plywood bonding substrate above-mentioned analyte supply port and above-mentioned blood cell diffusion barrier are set.
Check utensil according to this, when transferring the analyte that has been fed in the analyte supply port to measuring cell, by the cock body covering analyzing thing supply port that constitutes with elastic body, by pushing this cock body analyte is pressurizeed, do not need large-scale mechanical hook-ups such as pump, just can positively be carried out by simple bulldozing operation, and operating cost is also cheap.In addition, when in order to transfer analyte to measuring cell above-mentioned cock body having been carried out bulldozing operation, the air that accumulates in the space of above-mentioned stream, measuring cell is gone to the outside through plate, so, analyte is transferred to be full of the space in order, and the ormal weight of analyte promptly is transferred to measuring cell.In addition, by the blood cell diffusion barrier blood cell is separated, only with blood plasma from stream transfer chamber measuring cell, the blood supply fluid inspection uses.
And this checks utensil because can distinguish making layer lamination and substrate, and they are carried out bondingly constituting, this plywood stackedly constitutes by plate is carried out, and this substrate is provided with analyte supply port and blood cell diffusion barrier, so, easy to manufacture, can make cheap for manufacturing cost.
Be preferably in the said determination chamber, stream arranges the reagent filling part.Filling reagent in this reagent filling part, this reagent at measuring cell determination and analysis thing and and analyte response, or be used for when the mensuration of analyte, hindering and the reaction of desired substance, the material that becomes the reason of error at measurment are removed.For example, in measuring as the blood of biological body fluid components under the situation of glucose, in measuring cell or stream, drip and comprised NAD, 2-(4-iodobenzene)-3-(2,4 dinitro benzenes)-5-(2,4 disulfobenzene)-and the reagent of 2H-tetrazole, polyvinylpyrrolidone, phosphate buffer, gluconate dehydratase enzyme, diaphorase, make its drying.On the other hand, when measuring urea nitrogen, creatinine, dripping in measuring cell or stream has comprised the reagent of ascorbic acid oxidase, sodium alginate, o-phenylenediamine, phosphate buffer, urate oxidase, peroxidase, makes its drying.
On the above-mentioned plate that is constituted by porous material, a plurality of streams that arrive a plurality of measuring cells can be set also.According to this structure, can measure a plurality of kinds of same analyte.Particularly, under the situation that a plurality of streams and measuring cell are set, the analyte that is difficult to transfer to a plurality of measuring cells through each stream ormal weight by the transfer device that utilizes pump to drive in the past, and in this utility model, because the bulldozing operation by above-mentioned cock body makes the air in the space that accumulates in above-mentioned stream, measuring cell go to the outside through plate, so analyte is promptly transferred regulation to be full of the space to each measuring cell through above-mentioned each stream.In addition, as the reagent filling part reagent individually being filled in wherein respectively a part in the way of above-mentioned each stream, then when the reagent that disposes as configuration will exert an influence to stability together, produce good result.
Around above-mentioned analyte supply port, the weir dike of the outflow that prevents analyte is set preferably.As do, then can not make analyte positively from above-mentioned analyte supply port analyte is supplied to inside with flowing out.
The effect of utility model
As described above, according to the utility model, do not need large-scale mechanical hook-ups such as pump, just can positively carry out the handover of analyte by simple bulldozing operation, can carry out certain mensuration of analyte, and it is cheap that operating cost also becomes.In addition, because can distinguish making layer lamination and substrate, they are carried out bondingly constituting, so, easy to manufacture, can make cheap for manufacturing cost.
Description of drawings
Fig. 1 is the longitudinal section of an embodiment of expression inspection utensil of the present utility model.
Fig. 2 is the exploded perspective view of an embodiment of expression inspection utensil of the present utility model.
Fig. 3 is the longitudinal section of the program of expression when using inspection utensil of the present utility model to carry out the mensuration of blood analyte, (a) be illustrated in the analyte supply port analyte that drips, covered the state of analyte supply port by cock body, (b) expression pushes cock body, analyte has been transferred to the state of measuring cell.
Fig. 4 is the chart of the measurement result of expression blood analyte.
Embodiment
Below, the embodiment as inspection utensil of the present utility model illustrates the blood test utensil with reference to the accompanying drawings.
Fig. 1 represents the longitudinal section of blood test utensil, and Fig. 2 represents its exploded perspective view.Check shown in these each figure that utensil 100 is that adhesive base plate 1 constitutes with plywood 20.Form circular analyte supply port 11 at substrate 1, be provided with weir dike 12 at an upper portion thereof on every side.And, at weir dike 12 the circular protrusion 12a that further gives prominence to from upper surface is set.In addition, on weir dike 12, arrange with circular-arc outstanding jut 13 in the inboard.This weir dike 12 is adjacent to the cock body that is made of the butyl rubber elastomeric material and the mode that the inner space seals is constituted.Specifically, as cock body 5 weir dike 12 butts therewith, the circular protrusion 12a of the weir dike 12 edge part 5a of cock body 5 that nips then is so the inner space positively is sealed.As pushing cock body 5 under this state, then apply plus-pressure at the analyte (blood) that has been supplied to analyte supply port 11.Cock body 5 is by not shown dipper crowding gear pushing.
In addition, in the lower face side of substrate 1, circular recess 14 is set at the position in opposite directions with analyte supply port 11, here packs into blood cell is separated the blood cell diffusion barrier of removing 6 that is made of asymmetric aperture film.This blood cell diffusion barrier 6 is fixed on the substrate 1 by bonding agent (diagram is omitted).
In addition, side below substrate 1 is provided with two-dimensional bar code 15.To constitute by reading the mode that two-dimensional bar code 15 just can the discriminance analysis thing.In addition, this two-dimensional bar code 15 is checking that utensil 100 can be arranged on position arbitrarily.In addition, the material of substrate 1 uses the resin material of processing easily, for example can compatibly use AS resin (styreneo-acrylonitrile resin).
In addition, the upper surface at substrate 1 is provided with projection 16,17.This projection 16,17 is used for when optical detecting or electric greenhouse checking that utensil 100 positions.
Plywood 20 possesses through bonding agent (diagram omit) at the stacked 3 blocks of integrated plates of above-below direction, i.e. first plate 2, second plate 3 and the 3rd plate 4.On plywood 20, the inner measuring cell 7 that forms the composition of determination and analysis thing A in the side of analyte supply port 11, the stream 8 of the handover usefulness of formation analyte A between this measuring cell 7 and analyte supply port 11.
As shown in Figure 1 and Figure 2, stream 8 forms as described below.Namely, at first plate 2 and concentric position analyte supply port 11, be formed on the through hole 81 that above-below direction extends, and, be configured in first plate 2 below second plate 3 on with through hole 81 in opposite directions shape circular through hole 82 is set, dig the through slot 83 of wearing linearity towards the side from this, form stream 8 by these through holes 81 and through hole 82 and through slot 83.In addition, measuring cell 7 forms as described below.That is, in the front that has been arranged on the through slot 83 on second plate 3, to form circular through hole 71 with through slot 83 connected states, the inside of through hole 71 is made the measuring cell 7 of analyte A.
In addition, Fig. 1, inspection utensil 100 shown in Figure 2 have 8 measuring cells 7.Specifically, be formed for forming 8 through holes 71 of the circle of measuring cell 7 at this second plate 3.In addition, arrange and through hole 81 through hole 82 in opposite directions that is located on first plate 2, a through slot 83a of through hole 82 extensions from then on is branched off into 8 through slot 83c at branching portion 83b, at the front formation through hole 71 of these through slots 83c.8 measuring cells 7 are by through hole 71 and first plate 2 and 4 divisions of the 3rd plate.In addition, stream 8 is by through slot 83 and first plate 2 and 4 divisions of the 3rd plate.In addition, in stream 8, also comprise through hole 81.
First plate 2 and the 3rd plate 4 are watertightness and airproof plate, as its material, use the resin material of processing easily, for example can compatibly use AS resin (styreneo-acrylonitrile resin).
The for example PTFE(teflon as porous material that on the other hand, as second plate 3, can compatibly use watertightness, have gas penetration potential) film.So, when cock body 5 is carried out bulldozing operation, 7 when transferring analyte A from stream 8 to measuring cell, the air that accumulates in the space of these streams 8, measuring cell 7 is gone to the outside through second plate 3, analyte A is transferred to be full of the space in order, and the ormal weight of analyte A promptly is transferred to measuring cell 7.
In measuring cell 7, be provided with reagent filling part 9.Filling reagent in this reagent filling part 9, this reagent at measuring cell 7 determination and analysis thing A and with analyte A reaction, or be used for when the mensuration of analyte A, hindering and the reaction of desired substance, the material that becomes the reason of error at measurment are removed.As this reagent, for example in measuring as the blood of biological body fluid components under the situation of glucose, use has comprised NAD, 2-(4-iodobenzene)-3-(2,4 dinitro benzenes)-and 5-(2,4 disulfobenzene)-reagent of 2H-tetrazole, polyvinylpyrrolidone, phosphate buffer, gluconate dehydratase enzyme, diaphorase.This reagent is dripped in the measuring cell 7, make its drying.On the other hand, when measuring urea nitrogen, creatinine, use the reagent that has comprised ascorbic acid oxidase, sodium alginate, o-phenylenediamine, phosphate buffer, urate oxidase, peroxidase, this reagent is dripped in the measuring cell 7, make its drying.In addition, reagent filling part 9 also can be located at the part in the way of stream 8.
When at measuring cell 7 determination and analysis thing A, used transmitted light, catoptrical optical detecting, electrical measurement to be used.Under the situation of the optical detecting that uses transmitted light, first plate 2 and second plate 3, with the position of measuring cell 7 adjacency hyalomere T is set, and, make the bond layer (diagram is omitted) that plate is bonded to each other not hinder seeing through of light at the position with measuring cell 7 adjacency, by carrying out chromogenic reaction at measuring cell 7 by reagent and analyte A, from the below irradiates light of the 3rd plate 4, accept transmitted light on the top of first plate 2, be determined at the absorbance of measuring cell 7.In addition, the method as hyalomere T is set at first plate 2 and the 3rd plate 4 constitutes first plate 2 and the 3rd plate 4 by transparent resin, and the method that the position beyond the hyalomere T is coloured to black is fit to.
For the position beyond the hyalomere T is coloured to black, implement printing by the face (i.e. the face of second plate, 3 sides) in the inboard of first plate 2 and the 3rd plate 4, the method for part that forms black is suitable.So, because beyond hyalomere T, cover printed layers, on the other hand, there is not printed layers at hyalomere T, so, pit formed at hyalomere T.Make its drying as coating reagent in this pit, then can easily reagent be configured in the measuring cell.
As described above, as forming a plurality of streams 8 and measuring cell 7 at second plate 3 that is constituted by porous material, then can carry out multiple mensuration from an analyte A.Particularly under the situation that a plurality of measuring cells 7 and stream 8 are set, the analyte A that is difficult to transfer to a plurality of measuring cells 7 through each stream 8 ormal weight by the transfer device that utilizes pump to drive in the past, and make the air in the space that accumulates in stream 8, measuring cell 7 go to the outside through second plate 3 by the bulldozing operation of cock body 5, so, analyte A promptly transfers ormal weight through stream 8 to each measuring cell 7, to be full of the space.In addition, as with the part in the way of each measuring cell 7, stream 8 as the reagent filling part, respectively reagent individually is fills up in these reagent filling parts, then when the reagent that disposes as configuration will exert an influence to stability together, produces good result.
In addition, when determination and analysis thing A in measuring cell 7, also can carry out electrical measurement.That is, in measuring cell 7 configuration pair of electrodes, by to this a pair of electrifying electrodes, the conductivity of determination and analysis thing A etc.
In addition, on plywood 20, on one side be provided with two otch 21,22 at it.This otch 21,22 is that otch 2a, 3a, 4a and otch 2b, 3b, the 4b that overlaps the same position on the one side that has been located at each plate respectively constitutes.This otch 21,22 is used for when optical detecting or electrical measurement checking that utensil 100 positions.
Below, the program when illustrating that according to Fig. 3 the above-mentioned inspection utensil 100 of use carries out blood test.
At first, from the analyte supply port 11 that arranges on the substrate 1 analyte A is supplied to (with reference to Fig. 3 (a)) on the blood cell diffusion barrier 6.At this moment, owing to around analyte supply port 11, be provided with weir dike 12, so, can not cause the outflow of analyte A, can positively it be supplied to the inside of analyte supply port 11.In addition, owing on weir dike 12, be provided with circular-arc outstanding jut 13 in the inboard, so the surface of the skin by the puncture finger tip has been ladled out from the blood of puncture portion outflow by jut 13, can be towards analyte supply port 11 guide blood.After this, as this figure, cock body 5 coverings are entrenched in analyte supply port 11, push this cock body 5 by dipper crowding gear then, the analyte A that has been fed on the blood cell diffusion barrier 6 is applied plus-pressure, analyte A is by blood cell diffusion barrier 6, this moment, blood cell was separated, and only blood plasma is transferred to measuring cell 7(with reference to Fig. 3 (b) by stream 8.In addition, the analyte A that has been transplanted on the inside of plywood 20 is not illustrated).As described above, by pushing cock body 5,7 transfer from stream 8 to measuring cell being fed into analyte A in the analyte supply port 11, do not need the mechanical force of pump etc., just can positively carry out the handover of analyte A by shirtsleeve operation, and operating cost also becomes cheap.
In addition, as Fig. 1, Fig. 2, second plate 3 that forms the part of stream 8 is formed by watertightness, porous material (for example PTFE) with gas penetration potential, thus, when in order to transfer analyte A to measuring cell 7 cock body 5 having been carried out bulldozing operation, because the air that accumulates in the space of stream 8, measuring cell 7 is gone to the outside through second plate 3, so, analyte A is transferred to be full of the space in order, and the ormal weight of analyte A promptly is transferred to measuring cell 7.Particularly such as shown in Figure 1 and Figure 2, form the part of a plurality of streams 8 and measuring cell 7 at second plate 3 that is constituted by porous material, in the case, be difficult to through each stream 8 the analyte A of ormal weight is transferred to a plurality of measuring cells 7 by in the past the transfer device that utilizes pump to drive, and make the air in the space that accumulates in stream 8, measuring cell 7 go to the outside through second plate 3 by the bulldozing operation of cock body 5, thus, can promptly carry out the handover of the analyte A from from each stream 8 to each measuring cell 7.
And, be sent to the analyte A of measuring cell 7, carry out the mensuration of analyte A by the absorbance of measuring measuring cell 7.Perhaps, under the situation that pair of electrodes has been located at measuring cell 7, carried out the electrical measurement of analyte A by electrode.
Below, enumerate specific embodiment and describe.In this embodiment, the situation of measuring the glucose in the blood is described.
As substrate 1, first plate 2 and the 3rd plate 4, the plate that has used AS resin (styreneo-acrylonitrile resin) to make as second plate 3, has used the PTFE film of thick 75 μ m, aperture 1 μ m.In addition, as cock body 5, use the cock body of butyl rubber system, as blood cell diffusion barrier 6, used asymmetric aperture film.
In addition, in the measuring cell 7 as reagent filling part 9, dripping has comprised NAD3.6wt%, WST3[2-(4-iodobenzene)-3-(2,4 dinitro benzenes)-5-(2,4 disulfobenzene)-the 2H-tetrazole; Colleague chemical company system] the 10 μ l of reagent of 50mM phosphate buffer, gluconate dehydratase enzyme 2KU/ml, diaphorase 1KU/ml of 5.2wt%, polyvinylpyrrolidone 0.1wt%, PH7.5, make its drying.
Then, be respectively the analyte A of the blood of 70mg/dl, 150mg/dl, 300mg/dl from analyte supply port 11 concentration of glucose that drips to inside, after this cock body 5 is covered and be entrenched on the analyte supply port 11, it is carried out bulldozing operation, from stream 8 analyte A has been transplanted on the measuring cell 7.
The mensuration of analyte A, the transmitted light of use 430nm has been measured its absorbance.Its result is shown in the chart of Fig. 4.As can learning from this chart, which analyte A can both carry out certain mensuration for.
Description of reference numerals:
100 check utensil
11 analyte supply ports
12 weir dikes
1 substrate
20 plywoods
2 first plates
3 second plates (plate that is constituted by porous material)
4 the 3rd plates
6 blood cell diffusion barriers
7 measuring cells
71 through holes
8 streams
82 through holes
83 through slots
The A analyte

Claims (3)

1. the inspection utensil of a body fluid components is characterized in that:
Possess the analyte supply port to inner supply analysis thing,
Carry out the measuring cell of the mensuration of above-mentioned analyte,
Be communicated with above-mentioned analyte supply port and said determination chamber stream and
From the above-mentioned analyte that has supplied to above-mentioned analyte supply port blood cell is removed the blood cell diffusion barrier that the back is supplied with to above-mentioned stream;
By two watertightnesses and airproof plate, thickness direction be provided with through hole and through slot by watertightness and have plate holder that the porous material of gas penetration potential constitutes and go into and constitute plywood, be provided with said determination chamber and above-mentioned stream at this plywood;
The said determination chamber is divided by above-mentioned through hole and above-mentioned two watertightnesses and airproof plate, and above-mentioned stream is divided by above-mentioned through slot and above-mentioned two watertightnesses and airproof plate,
With above-mentioned plywood bonding substrate be provided with above-mentioned analyte supply port and above-mentioned blood cell diffusion barrier.
2. the inspection utensil of body fluid components according to claim 1 is characterized in that: be formed with a plurality of above-mentioned through holes and a plurality of above-mentioned through slot at the above-mentioned plate that is made of porous material.
3. the inspection utensil of body fluid components according to claim 1 and 2 is characterized in that: be provided with the weir dike that prevents that above-mentioned analyte from flowing out around above-mentioned analyte supply port.
CN 201320068524 2012-12-12 2013-02-06 Body fluid ingredient detector Expired - Lifetime CN203133091U (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012-271434 2012-12-12
JP2012271434A JP5931709B2 (en) 2012-12-12 2012-12-12 Body fluid component testing equipment

Publications (1)

Publication Number Publication Date
CN203133091U true CN203133091U (en) 2013-08-14

Family

ID=48941062

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 201320068524 Expired - Lifetime CN203133091U (en) 2012-12-12 2013-02-06 Body fluid ingredient detector

Country Status (2)

Country Link
JP (1) JP5931709B2 (en)
CN (1) CN203133091U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106289934A (en) * 2015-06-23 2017-01-04 台达电子工业股份有限公司 Pipe-line mixer

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101830759B1 (en) * 2015-10-26 2018-02-21 광운대학교 산학협력단 Smart pipette for on-site whole blood analysis
KR101986429B1 (en) * 2017-11-16 2019-06-10 (주) 비비비 Lab on a chip having negative pressure generator and using method thereof
WO2021261399A1 (en) * 2020-06-22 2021-12-30 積水化学工業株式会社 Inspection chip and liquid introduction method

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2156226C (en) * 1994-08-25 1999-02-23 Takayuki Taguchi Biological fluid analyzing device and method
JP3856436B2 (en) * 2002-03-01 2006-12-13 松下電器産業株式会社 Biosensor
CN1650173B (en) * 2002-04-30 2012-06-06 爱科来株式会社 Analysis instrument, sample analysis method and analysis device using the instrument, and method of forming opening in the instrument
CN101031800B (en) * 2004-09-30 2011-01-05 爱科来株式会社 Analyzer
GB0525997D0 (en) * 2005-12-21 2006-02-01 Oxford Biosensors Ltd Micro-fluidic structures
JP2007248101A (en) * 2006-03-14 2007-09-27 Ttm:Kk Inspection instrument of liquid fluid and inspection method using it
KR20100053500A (en) * 2007-09-14 2010-05-20 주식회사 티티엠 Liquid fluid testing instrument and testing method
WO2009037784A1 (en) * 2007-09-21 2009-03-26 Tya K. K. Analytical instrument for body fluid component
JPWO2009110089A1 (en) * 2008-03-07 2011-07-14 株式会社ティー・ワイ・エー Body fluid component analyzer
JP5339554B2 (en) * 2009-07-03 2013-11-13 株式会社ティー・ティー・エム Body fluid component analyzer
JP2011103826A (en) * 2009-11-19 2011-06-02 Nitto Boseki Co Ltd Method for measuring adp or specific substance producing adp by enzymatic reaction by dry chemistry and examination instrument used therefor
KR101787791B1 (en) * 2010-04-14 2017-10-19 니토 보세키 가부시기가이샤 Test instrument for measuring analyte in sample, and method for measuring analyte using same
US9116089B2 (en) * 2010-11-10 2015-08-25 Boehringer Ingelheim Microparts Gmbh Device for filtering blood

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106289934A (en) * 2015-06-23 2017-01-04 台达电子工业股份有限公司 Pipe-line mixer
CN106289934B (en) * 2015-06-23 2020-01-03 台达电子工业股份有限公司 Pipeline mixer

Also Published As

Publication number Publication date
JP2014115246A (en) 2014-06-26
JP5931709B2 (en) 2016-06-08

Similar Documents

Publication Publication Date Title
CN203133091U (en) Body fluid ingredient detector
AU2001262923B2 (en) Capillary flow control in a fluidic diagnostic device
Lan et al. based electroanalytical devices with an integrated, stable reference electrode
ES2245035T3 (en) MICROFLUIDIC ANALYZER MODULE.
US20110233059A1 (en) Microfluid sensor
US20060002817A1 (en) Flow modulation devices
EP1612430A2 (en) Methods for modulation of flow in a microfluidic pathway
CN101568828B (en) Ion sensor for fluid and method for its manufacture
CN101421616A (en) Ammeter detects the miniaturization biology sensor of optimizing
US20030200644A1 (en) Electrochemical test strip cards that include an integral dessicant
CN103487490A (en) Analysis chip and analysis apparatus
CN101014851A (en) Electrochemical cell and method of making an electrochemical cell
KR20020092402A (en) Capillary flow control in a medical diagnostic device
JP2007248101A (en) Inspection instrument of liquid fluid and inspection method using it
CN101663578B (en) Electrophoresis chip and electrophoresis apparatus
KR20020088521A (en) Biosensors with porous chromatographic membranes and enhanced sampling capability
JP4594044B2 (en) Sensor card for determining an analyte in a liquid or gas sample and method of manufacturing such a sensor card
WO2016194392A1 (en) Biosensor chip and biosensor device
CN111344062B (en) Sensor cartridge
KR20150059413A (en) Test method of sample and microfluidic device
JP4733838B2 (en) Body fluid component inspection method and inspection instrument used therefor
US7797987B2 (en) Test sensor with a side vent and method of making the same
CN112203766A (en) Multilayer belt and method for producing a multilayer belt
TWI239397B (en) Electro-chemical electrode sensing test sheet for screen printing and its manufacturing method
Calvo-López et al. Biomedical point-of-care microanalyzer for potentiometric determination of ammonium ion in plasma and whole blood

Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20190619

Address after: Osaka

Patentee after: AIKUS Corp.

Address before: Osaka

Patentee before: TTM

TR01 Transfer of patent right
CX01 Expiry of patent term

Granted publication date: 20130814

CX01 Expiry of patent term