CN203089978U - Vacuum delivery device with vapor hydrogen peroxide sterilization - Google Patents

Vacuum delivery device with vapor hydrogen peroxide sterilization Download PDF

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Publication number
CN203089978U
CN203089978U CN 201320087562 CN201320087562U CN203089978U CN 203089978 U CN203089978 U CN 203089978U CN 201320087562 CN201320087562 CN 201320087562 CN 201320087562 U CN201320087562 U CN 201320087562U CN 203089978 U CN203089978 U CN 203089978U
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CN
China
Prior art keywords
vacuum
hydrogen peroxide
generator
outfan
vacuum chamber
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Withdrawn - After Issue
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CN 201320087562
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Chinese (zh)
Inventor
叶大林
夏信群
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HANGZHOU TAILIN BIOTECHNOLOGY EQUIPMENT CO Ltd
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HANGZHOU TAILIN BIOTECHNOLOGY EQUIPMENT CO Ltd
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Publication of CN203089978U publication Critical patent/CN203089978U/en
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Abstract

The utility model discloses a vacuum delivery device with vapor hydrogen peroxide sterilization. The output end of a vapor hydrogen peroxide generation device is communicated with a vacuum chamber, a sealing device is used for sealing a cabin door in the vacuum chamber; a first high-vacuum generator and a second high-vacuum generator can enable the vacuum chamber to be in two vacuum degree states; the first high-vacuum generator also has the function of discharging vapor hydrogen peroxide in the vacuum chamber; the output end of an emptying device is communicated with the vacuum chamber; and a parameter monitoring device is used for monitoring the concentration, the temperature, the humidity and the vacuum degree of the vapor hydrogen peroxide in the vacuum chamber. The delivery device is short in sterilization period, non-toxic and pollution-free, harmless to equipment and high in safety.

Description

A kind of transfer device of vacuum type vaporized hydrogen peroxide sterilization
Technical field
This utility model belongs to biomedical sterilizing installation technical field, relates to a kind of transfer device of vacuum type vaporized hydrogen peroxide sterilization.
Background technology
2010 editions GMP require to produce according to sterile preparation to eye drop preparation, and adopt sterile production technology that the sterilization of packaging materials such as eyedrops bottle has been brought bigger challenge.Because the macromolecular material (as PE or PET) that packing material adopted can only adopt low temperature sterilization, and traditional low temperature sterilization mode, as EO and irradiation sterilization, be subject to sterilization process and equipment characteristic, this sterilization process can't be integrated in the sterile production flow process of eye drop.
Summary of the invention
This utility model provides a kind of eye-drop liquid bottle sterilizing installation at the deficiencies in the prior art.
For achieving the above object, this utility model is taked following design:
A kind of transfer device of vacuum type vaporized hydrogen peroxide sterilization comprises vacuum chamber body, vaporized hydrogen peroxide generating means, sealing device, the first fine vacuum generator, the second fine vacuum generator, emptying device and parameter monitor device.The outfan of hydrogen peroxide generating means and vacuum chamber sports association are logical, and sealing device is used for hatch door in the vacuum chamber body is sealed; The first fine vacuum generator and the second fine vacuum generator make the vacuum chamber body be in two kinds of vacuum states respectively; The described first fine vacuum generator also has vaporized hydrogen peroxide function in the discharging vacuum chamber body; The outfan of described emptying device and vacuum chamber sports association are logical; Described parameter monitor device is used to monitor the intravital concentration of hydrogen peroxide of vacuum chamber, temperature, humidity and vacuum.
Described vaporized hydrogen peroxide generating means comprises medicine system, vaporized hydrogen peroxide generator, heater, filter, quantitative air intake control system and electromagnetic valve; The hydrogenperoxide steam generator that adds injects the vaporized hydrogen peroxide generator through medicine system, filtrated air enters the vaporized hydrogen peroxide generator through electromagnetic valve, quantitative air intake control system and filter successively, the outfan of vaporized hydrogen peroxide generator is the outfan of vaporized hydrogen peroxide generating means, and the vaporized hydrogen peroxide generator is provided with heater with the pipeline that the vacuum chamber body is connected; Described heater is arranged on vacuum chamber body top, and medicine system is arranged on the side of vacuum chamber body, and its below is the vaporized hydrogen peroxide generator.
Described sealing device comprises first electromagnetic valve, second electromagnetic valve, the 3rd electromagnetic valve, Pressure gauge, gas-flow closure bar and vacuum generator; Described first electromagnetic valve is used to control the inflation of gas-flow closure bar, and described second electromagnetic valve is used to control vacuum generator, and vacuum generator is by the 3rd electromagnetic valve and gas-flow closure bar UNICOM, the gas-flow closure bar be arranged on hatch door around; The top of hatch door is provided with gas-flow closure bar Pressure gauge, and the manometric below of gas-flow closure bar has door open button, door close button, the display lamp that opens the door, alarm and emergency stop switch.
The described first fine vacuum generator comprises Vacuum ball valve, hydrogen peroxide catalyzed decomposer, relief valve, water ring vacuum pump and valve, the input of Vacuum ball valve and vacuum chamber sports association are logical, the outfan of Vacuum ball valve is connected with the input of hydrogen peroxide catalyzed decomposer, the outfan of hydrogen peroxide catalyzed decomposer is connected with the input of relief valve, and the outfan of relief valve is connected with the water ring vacuum pump input; Inlet pipeline is connected with water ring vacuum pump by valve.
The described second fine vacuum generator comprises Pneumatic vacuum ball valve, relief valve, sliding vane rotary vacuum pump and oil mist separator, the input of Pneumatic vacuum ball valve and vacuum chamber sports association are logical, the outfan of Pneumatic vacuum ball valve is connected with the input of relief valve, the outfan of relief valve is connected with the input of sliding vane rotary vacuum pump, and the outfan of sliding vane rotary vacuum pump is connected with oil mist separator.
Described emptying device comprises sterilizing filter and Vacuum ball valve, and filtrated air enters the vacuum chamber body by Vacuum ball valve and sterilizing filter successively.
Described parameter monitor device comprises vaccum stop valve, sampling pump, concentrations of vapor hydrogen peroxide monitoring means, temperature collect module, humidity acquisition module, vacuum acquisition module and PLC control system; The input of vaccum stop valve and vacuum chamber sports association are logical, and the outfan of vaccum stop valve is connected with the input of sampling pump, and the sampling delivery side of pump is connected with the concentrations of vapor hydrogen peroxide monitoring means; Temperature collect module, humidity acquisition module and vacuum acquisition module are gathered the intravital temperature of vacuum chamber, humidity and vacuum respectively; The outfan of the outfan of the outfan of temperature collect module, humidity acquisition module, vacuum acquisition module, concentration of hydrogen peroxide monitoring means all are connected with PLC control system signal, and described PLC control system also is connected with display and printer.
The beneficial effects of the utility model:
Vacuum in the chamber, and adopt pulse jet vaporized hydrogen peroxide mode to reach the effect of not having the sterilization dead angle: to make full use of vacuum technique, gaseous hydrogen peroxide is delivered to the surfaces externally and internally of eye drop bottle in the vacuum chamber, need not any assisting agitating apparatus, hydrogen peroxide gas just can arrive in the bottle fast, the sterilization dead angle is accomplished not have in extraordinary each position that is distributed in.
Sterilising cycle is short: make full use of vacuum technique equally in the residual stage of row, by evacuation repeatedly with charge into the fresh sterile air, can apace the vaporized hydrogen peroxide gas in chamber and the pipeline be discharged to below the safe concentration, shorten sterilising cycle.
Nontoxic pollution-free, harmless to equipment, safe: vaporized hydrogen peroxide has favorable compatibility to eye drop bottle material, and the end product of its decomposition simultaneously is water and oxygen, can not cause big infringement.Sterilize in addition and carry out under vacuum condition, vaporized hydrogen peroxide leakage probability is extremely low, safe.
Description of drawings
Fig. 1 is this utility model structural representation.
Fig. 2 is this utility model machine drawing.
The specific embodiment
The utility model is described in further detail below in conjunction with accompanying drawing.
As 1 and shown in Figure 2, present embodiment comprises vacuum chamber body, vaporized hydrogen peroxide generating means, sealing device, the first fine vacuum generator, the second fine vacuum generator, emptying device and parameter monitor device.The outfan of hydrogen peroxide generating means and vacuum chamber sports association are logical, and sealing device is used for hatch door in the vacuum chamber body is sealed; The first fine vacuum generator and the second fine vacuum generator make the vacuum chamber body be in two kinds of vacuum states respectively; The described first fine vacuum generator also has vaporized hydrogen peroxide function in the discharging vacuum chamber body; The outfan of described emptying device and vacuum chamber sports association are logical; Described parameter monitor device is used to monitor the intravital concentrations of vapor hydrogen peroxide of vacuum chamber, temperature, humidity and vacuum.
Described vaporized hydrogen peroxide generating means comprises medicine system, vaporized hydrogen peroxide generator, heater, filter, quantitative air intake control system and electromagnetic valve; The hydrogenperoxide steam generator that adds injects the vaporized hydrogen peroxide generator through medicine system, filtrated air enters the vaporized hydrogen peroxide generator through electromagnetic valve, quantitative air intake control system and filter successively, the outfan of vaporized hydrogen peroxide generator is the outfan of vaporized hydrogen peroxide generating means, the vaporized hydrogen peroxide generator is provided with heater with the pipeline that the vacuum chamber body is connected, and is used to heat the hydrogen peroxide of vaporization; Described heater 1 is arranged on vacuum chamber body top, and medicine system is arranged on the side of vacuum chamber body, and its below is a hydrogen peroxide generator 4.
Described sealing device comprises first electromagnetic valve, second electromagnetic valve, the 3rd electromagnetic valve, Pressure gauge, gas-flow closure bar and vacuum generator; Described first electromagnetic valve is used to control the inflation of gas-flow closure bar, and described second electromagnetic valve is used to control vacuum generator, and vacuum generator is by the 3rd electromagnetic valve and gas-flow closure bar UNICOM, the gas-flow closure bar be arranged on hatch door around; The top is provided with gas-flow closure bar Pressure gauge 12, and the manometric below of gas-flow closure bar has door open button 11, door close button 10, alarm 8 and emergency stop switch 9, is the display lamp that opens the door directly over the door open button 11.
The described first fine vacuum generator comprises Vacuum ball valve 6, hydrogen peroxide catalyzed decomposer, relief valve, water ring vacuum pump 7 and hand-operated valve, the input of Vacuum ball valve and vacuum chamber sports association are logical, the outfan of Vacuum ball valve is connected with the input of hydrogen peroxide catalyzed decomposer, the outfan of hydrogen peroxide catalyzed decomposer is connected with the input of relief valve, and the outfan of relief valve is connected with the water ring vacuum pump input; Inlet pipeline is connected with water ring vacuum pump by valve; Hydrogen peroxide catalyzed decomposer makes and discharges environmental protection more.
The described second fine vacuum generator comprises Vacuum ball valve, relief valve, sliding vane rotary vacuum pump 14 and oil mist separator, the input of Vacuum ball valve and vacuum chamber sports association are logical, the outfan of Vacuum ball valve is connected with the input of relief valve, the outfan of relief valve is connected with the input of sliding vane rotary vacuum pump 14, and the outfan of sliding vane rotary vacuum pump 14 is connected with oil mist separator.
Described emptying device comprises sterilizing filter and Vacuum ball valve, and filtrated air enters the vacuum chamber body by Vacuum ball valve and sterilizing filter successively.
Described parameter monitor device comprises vaccum stop valve, sampling pump, concentrations of vapor hydrogen peroxide monitoring means, temperature collect module, humidity acquisition module, vacuum acquisition module and PLC control system; The input of vaccum stop valve and vacuum chamber sports association are logical, and the outfan of vaccum stop valve is connected with the input of sampling pump, and the sampling delivery side of pump is connected with the concentrations of vapor hydrogen peroxide monitoring means; Temperature collect module, humidity acquisition module and vacuum acquisition module are gathered the intravital temperature of vacuum chamber, humidity and vacuum respectively; The outfan of the outfan of the outfan of temperature collect module, humidity acquisition module, vacuum acquisition module, concentration of hydrogen peroxide monitoring means all are connected with PLC control system signal, described PLC control system also is connected with display and printer, concentrations of vapor hydrogen peroxide monitoring means and medicine system are set together, constitute dosing and concentration monitor device 2, its next door is electric box 3 and hydrogen peroxide liquid bottle rack 5.
The sterilization flow process was divided into for four steps:
Dry--evacuation--sterilization---row is residual, specific as follows:
Drying stage: with the vacuum chamber body by heating, utilize the second fine vacuum generator evacuation to carry out drying, hydrogen peroxide gas produces condensation when preventing to sterilize, and influences sterilization effect.
Vacuumizing phase: with vacuum chamber body evacuation, be beneficial to hydrogen peroxide gas and inject diffusion, and when guaranteeing sterilization hydrogen peroxide gas at the uniform distribution of sterilization interior volume.
Sterilization phase: the vaporized hydrogen peroxide steriliser produces the hydrogen peroxide vapor of high concentration, enters vacuum chamber inside under pressure fast; When the force value that reaches setting, stop to inject hydrogen peroxide gas, keep certain hour, finish up to sterilization.
Arrange the residual stage: sterilization finishes the back by first fine vacuum generator evacuation and the emptying, and residual hydrogen dioxide and catabolite steam and oxygen discharge with vacuum chamber body inside reach below the safe concentration until residual hydrogen dioxide concentration.
The above-mentioned specific embodiment is used for explaining this utility model; rather than this utility model limited; in the protection domain of spirit of the present utility model and claim, any modification and change to this utility model is made all fall into protection domain of the present utility model.

Claims (7)

1. the transfer device of vacuum type vaporized hydrogen peroxide sterilization, comprise vacuum chamber body, vaporized hydrogen peroxide generating means, sealing device, the first fine vacuum generator, the second fine vacuum generator, emptying device and parameter monitor device, it is characterized in that: the outfan of vaporized hydrogen peroxide generating means and vacuum chamber sports association are logical, and sealing device is used for hatch door in the vacuum chamber body is sealed; The first fine vacuum generator and the second fine vacuum generator make the vacuum chamber body be in two kinds of vacuum states respectively; The described first fine vacuum generator also has vaporized hydrogen peroxide function in the discharging vacuum chamber body; The outfan of described emptying device and vacuum chamber sports association are logical; Described parameter monitor device is used to monitor the intravital concentrations of vapor hydrogen peroxide of vacuum chamber, temperature, humidity and vacuum.
2. the transfer device of a kind of vacuum type vaporized hydrogen peroxide sterilization according to claim 1 is characterized in that: described vaporized hydrogen peroxide generating means comprises medicine system, vaporized hydrogen peroxide generator, heater, filter, quantitative air intake control system and electromagnetic valve; The hydrogenperoxide steam generator that adds injects the vaporized hydrogen peroxide generator through medicine system, filtrated air enters the vaporized hydrogen peroxide generator through electromagnetic valve, quantitative air intake control system and filter successively, the outfan of vaporized hydrogen peroxide generator is the outfan of vaporized hydrogen peroxide generating means, and the vaporized hydrogen peroxide generator is provided with heater with the pipeline that the vacuum chamber body is connected; Described heater is arranged on vacuum chamber body top, and medicine system is arranged on the side of vacuum chamber body, and its below is the vaporized hydrogen peroxide generator.
3. the transfer device of a kind of vacuum type vaporized hydrogen peroxide sterilization according to claim 1, it is characterized in that: described sealing device comprises first electromagnetic valve, second electromagnetic valve, the 3rd electromagnetic valve, Pressure gauge, gas-flow closure bar and vacuum generator; Described first electromagnetic valve is used to control the inflation of gas-flow closure bar, and described second electromagnetic valve is used to control vacuum generator, and vacuum generator is by the 3rd electromagnetic valve and gas-flow closure bar UNICOM, the gas-flow closure bar be arranged on hatch door around; The top of hatch door is provided with gas-flow closure bar Pressure gauge, and the manometric below of gas-flow closure bar has door open button, door close button, the display lamp that opens the door, alarm and emergency stop switch.
4. the transfer device of a kind of vacuum type vaporized hydrogen peroxide sterilization according to claim 1, it is characterized in that: the described first fine vacuum generator comprises Vacuum ball valve, hydrogen peroxide catalyzed decomposer, relief valve, water ring vacuum pump and valve, the input of Vacuum ball valve and vacuum chamber sports association are logical, the outfan of Vacuum ball valve is connected with the input of hydrogen peroxide catalyzed decomposer, the outfan of hydrogen peroxide catalyzed decomposer is connected with the input of relief valve, and the outfan of relief valve is connected with the water ring vacuum pump input; Inlet pipeline is connected with water ring vacuum pump by valve.
5. the transfer device of a kind of vacuum type vaporized hydrogen peroxide sterilization according to claim 1, it is characterized in that: the described second fine vacuum generator comprises Pneumatic vacuum ball valve, relief valve, sliding vane rotary vacuum pump and oil mist separator, the input of Pneumatic vacuum ball valve and vacuum chamber sports association are logical, the outfan of Pneumatic vacuum ball valve is connected with the input of relief valve, the outfan of relief valve is connected with the input of sliding vane rotary vacuum pump, and the outfan of sliding vane rotary vacuum pump is connected with oil mist separator.
6. the transfer device of a kind of vacuum type vaporized hydrogen peroxide sterilization according to claim 1, it is characterized in that: described emptying device comprises sterilizing filter and Vacuum ball valve, filtrated air enters the vacuum chamber body by Vacuum ball valve and sterilizing filter successively.
7. the transfer device of a kind of vacuum type vaporized hydrogen peroxide sterilization according to claim 1, it is characterized in that: described parameter monitor device comprises vaccum stop valve, sampling pump, concentrations of vapor hydrogen peroxide monitoring means, temperature collect module, humidity acquisition module, vacuum acquisition module and PLC control system; The input of vaccum stop valve and vacuum chamber sports association are logical, and the outfan of vaccum stop valve is connected with the input of sampling pump, and the sampling delivery side of pump is connected with the concentrations of vapor hydrogen peroxide monitoring means; Temperature collect module, humidity acquisition module and vacuum acquisition module are gathered the intravital temperature of vacuum chamber, humidity and vacuum respectively; The outfan of the outfan of the outfan of temperature collect module, humidity acquisition module, vacuum acquisition module, concentration of hydrogen peroxide monitoring means all are connected with PLC control system signal, and described PLC control system also is connected with display and printer.
CN 201320087562 2013-02-26 2013-02-26 Vacuum delivery device with vapor hydrogen peroxide sterilization Withdrawn - After Issue CN203089978U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201320087562 CN203089978U (en) 2013-02-26 2013-02-26 Vacuum delivery device with vapor hydrogen peroxide sterilization

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201320087562 CN203089978U (en) 2013-02-26 2013-02-26 Vacuum delivery device with vapor hydrogen peroxide sterilization

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CN203089978U true CN203089978U (en) 2013-07-31

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103110970A (en) * 2013-02-26 2013-05-22 杭州泰林生物技术设备有限公司 Vacuum type transmission device for vaporization hydrogen peroxide sterilization
CN108939116A (en) * 2018-07-16 2018-12-07 温州维科生物实验设备有限公司 Indoor VHP disinfection system and its operating method
CN109985261A (en) * 2017-12-29 2019-07-09 伊西康公司 Sterilize pallet

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103110970A (en) * 2013-02-26 2013-05-22 杭州泰林生物技术设备有限公司 Vacuum type transmission device for vaporization hydrogen peroxide sterilization
CN109985261A (en) * 2017-12-29 2019-07-09 伊西康公司 Sterilize pallet
CN108939116A (en) * 2018-07-16 2018-12-07 温州维科生物实验设备有限公司 Indoor VHP disinfection system and its operating method

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C14 Grant of patent or utility model
GR01 Patent grant
AV01 Patent right actively abandoned

Granted publication date: 20130731

Effective date of abandoning: 20141015

RGAV Abandon patent right to avoid regrant