CN202892981U - High-capacity plasma separation cup - Google Patents

High-capacity plasma separation cup Download PDF

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Publication number
CN202892981U
CN202892981U CN 201220502470 CN201220502470U CN202892981U CN 202892981 U CN202892981 U CN 202892981U CN 201220502470 CN201220502470 CN 201220502470 CN 201220502470 U CN201220502470 U CN 201220502470U CN 202892981 U CN202892981 U CN 202892981U
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CN
China
Prior art keywords
cup
nuclear
plasma
plasma separation
core
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN 201220502470
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Chinese (zh)
Inventor
张世兵
温书连
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sichuan Nigale Biotechnology Co Ltd
Original Assignee
Sichuan Nigale Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sichuan Nigale Biomedical Inc filed Critical Sichuan Nigale Biomedical Inc
Priority to CN 201220502470 priority Critical patent/CN202892981U/en
Application granted granted Critical
Publication of CN202892981U publication Critical patent/CN202892981U/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Abstract

The utility model relates to a high-capacity plasma separation cup, which comprises a fixed head, a sealing cup, a sealing gasket, a sealing ring, an upper cover, a lower cover, a cup cover, a composite cup core, a cup body and a central pipe. The composite cup core consists of a fixed ring, a cup core and a guide disc. On the basis that the outer diameter of the cup body of the separation cup is unchanged, the outer diameter of the cup core is expanded to be 22-35mm to form the high-capacity plasma separation cup with capacity of 320-370ml.

Description

Large capacity plasma separation cup
Technical field
The utility model relates to a kind of medicine equipment, particularly a kind of large capacity plasma separation cup that significantly increases displacement volume in the situation of separate cup cup size constancy.
Background technology
The plasma separation cup is to utilize centrifugal principle to carry out one of important means of plasma separation in the modern biomedical engineering field, its basic principle is to utilize blood plasma collecting machine to drive plasma separation cup High Rotation Speed, make the haemocyte in the plasma separation cup carry out undamaged the separation with plasma fraction, to extract plasma fraction.
The specification capacity of at present plasma separation cup use is about 280 milliliters, the displacement volume of plasma separation cup mainly is to be determined by the plasma separation cavity volume that forms between cup in the plasma separation cup and the cup nuclear, this capacity makes the plasma separation cup when carrying out sampled plasma, and the sampled plasma amount that once gathers circulation can only reach about 400 milliliters.Because human body and mammal such as horse, the blood characteristics of ox etc. is close, but doubly a lot of greater than human body aspect build, therefore, in related scientific research, need of production gathers large mammal such as horse, during the blood plasma of ox etc., once gather often very large requirement of total amount, at present artificial collection commonly used, separate, the mode that feeds back is carried out, this mode exists loaded down with trivial details, working strength is large, the defective that pollution risk is large, but when the plasma separation cup that uses the work on hand capacity carries out the machine collection, because it is less that one way gathers plasma volume, when the collection total amount is very large, there is again the global cycle of needs often, the defective that time is long.
Summary of the invention
Above defective in view of present normal plasma separate cup, the purpose of this utility model is a kind of external structure, size that does not change existing plasma separation cup of design, significantly increase the separate cup displacement volume, the specification capacity of separate cup is increased to about 360 milliliters, and once the plasma collection amount of collection circulation can reach the large capacity plasma separation cup about 500 milliliters.
The large capacity plasma separation cup that the utility model proposes is realized above-mentioned purpose by following architectural feature:
Large capacity plasma separation cup of the present utility model comprises static head, obturating cup, sealing gasket, sealing ring, upper cover, lower cover, bowl cover, cup nuclear, cup, central tube, cup nuclear is connected with cup, it is characterized in that cup nuclear is compound cup nuclear, this compound cup nuclear is made of retainer ring, cup nuclear core, positioning disk, retainer ring welds by pad one with cup nuclear core, blood plasma, haemocyte overflow seam are arranged between the two, cup nuclear core and positioning disk jointly form plasma separation chamber with cup by pad two welding between the two.
In order significantly to increase the displacement volume of above-mentioned Centrifuge Cup, the utility model is examined cup core on the constant basis of above-mentioned Centrifuge Cup cup outside dimension outside dimension expands to 22-35mm, is the large capacity plasma separation cup of 320-370ml thereby form volume.
Operation principle of the present utility model is as follows:
This novel high-capacity plasma separation cup and blood plasma collecting machine are used, separate cup is under the drive of blood plasma collecting machine, cup, bowl cover, compound cup nuclear part High Rotation Speed, by static fixing entrance, lower cover, central tube flows into the interior anticoagulated whole blood of rotation cup under centrifugal action, separate in the plasma separation chamber that between cup and compound cup nuclear, forms, anticoagulated whole blood is isolated the haemocyte layer of distal end and the plasma layer of proximal part, after the haemocyte that is separated in the plasma separation chamber fills up, plasma layer is pushed into the plasma collection chamber of separate cup by the overflow channel on the compound cup nuclear, the blood plasma overflow channel that forms by upper cover and lower cover flows to static head outlet, blood plasma enters plasma collection container, the blood platelet that density is less in blood cell composition and leucocyte composition enter the plasma collection chamber, this moment separate cup in without plasma fraction, and be full of by blood cell composition, and when overflowing by the blood plasma overflow channel, the blood plasma collecting machine sniffer detects cell component automatically, and blood plasma collecting machine stops to gather the feedback program that enters haemocyte automatically.
The utility model possesses following superiority:
1, security: machine moves whole setting programs automatically, and is safe and reliable;
2, versatility: cup appearance and size and install and use size without change, realize being used with the conventional blood plasma collecting machine that uses, do not need to design and produce separately corollary equipment.
3, quickness and high efficiency: avoided manual collection and common capacity separate cup loaded down with trivial details, the time is long, efficient is low.
Description of drawings
Fig. 1 is the assembly structure schematic diagram of the large capacity plasma separation of the utility model cup.
Fig. 2 is the compound cup nuclear assembly structure schematic diagram of the large capacity plasma separation of the utility model cup.
Among the figure: 1 static 2 obturating cups, 3 sealing gaskets, 4 sealing rings, 5 bowl covers, 6 upper covers, 7 lower covers, 8 cups, 9 compound cup are examined 10 central tubes, 11 blood entrances, 12 blood plasma and are exported 14 plasma separation chambeies, 13 plasma collection chambeies, 15 retainer rings, 16 pads, 17 blood plasma/haemocyte and overflow 18 glasss of nuclear of seam core, 19 pads, 20 positioning disks.
The specific embodiment
Embodiment 1
The large capacity plasma separation of the utility model cup is made of static 1, obturating cup 2, sealing gasket 3, sealing ring 4, bowl cover 5, upper cover 6, lower cover 7, cup 8, compound cup nuclear 9, central tube 10 as shown in the figure.Compound cup nuclear 9 is comprised of retainer ring 15, cup nuclear core 18, positioning disk 20.Retainer ring 15 welds by pad 1 with a glass nuclear core 18, and blood plasma, haemocyte overflow seam 17 are arranged between the two, and glass nuclear core 18 passes through pad 2 19 welding with positioning disk 20, jointly forms plasma separation chambeies 14 with cup 8 between the two.
In the present embodiment, the outside dimension of cup nuclear core 18 is 22mm, and the disengagement chamber volume is 370ml.By static 1 fixing blood entrance 11, lower cover 7, central tube 10 flows into the anticoagulated whole blood of rotation cup 8 under centrifugal action, separate in the large capacity plasma separation chamber 14 that positioning disk 20 by compound cup nuclear 9 forms between the cup nuclear core 18 of cup 8 and compound cup nuclear 9, anticoagulated whole blood is isolated the haemocyte layer of distal end and the plasma layer of proximal part, after plasma separation chamber 14 separated haemocytes fill up, plasma layer overflows the plasma collection chamber 13 that seam 17 is pushed into separate cup by the blood plasma/haemocyte of compound cup nuclear 9, the blood plasma overflow channel that forms by upper cover 6 and lower cover 7 flows to static 1 blood plasma outlet 12, blood plasma enters plasma collection container, the blood platelet that density is less in blood cell composition and leucocyte composition enter plasma collection chamber 13, this moment separate cup in without plasma fraction, and be full of by blood cell composition, and when overflowing by the blood plasma overflow channel, the blood plasma collecting machine sniffer detects cell component automatically, blood plasma collecting machine stops to gather automatically, carries out the feedback program of haemocyte.
Embodiment 2
The large capacity plasma separation of the utility model cup is made of static 1, obturating cup 2, sealing gasket 3, sealing ring 4, bowl cover 5, upper cover 6, lower cover 7, cup 8, compound cup nuclear 9, central tube 10 as shown in the figure.Compound cup nuclear is comprised of retainer ring 15, cup nuclear core 18, positioning disk 20.Retainer ring 15 welds by pad 1 with a glass nuclear core 18, and blood plasma, haemocyte overflow seam 17 are arranged between the two, and glass nuclear core 18 passes through pad 2 19 welding with positioning disk 20, jointly forms plasma separation chambeies 14 with cup 8 between the two.
In the present embodiment, the outside dimension of cup nuclear core 18 is 35mm, and the disengagement chamber volume is 320ml.
All the other are identical with embodiment 1.
Embodiment 3
The large capacity plasma separation of the utility model cup is made of static 1, obturating cup 2, sealing gasket 3, sealing ring 4, bowl cover 5, upper cover 6, lower cover 7, cup 8, compound cup nuclear 9, central tube 10 as shown in the figure.Compound cup nuclear is comprised of retainer ring 15, cup nuclear core 18, positioning disk 20.Retainer ring 15 welds by pad 1 with a glass nuclear core 18, and blood plasma, haemocyte overflow seam 17 are arranged between the two, and glass nuclear core 18 passes through pad 2 19 welding with positioning disk 20, jointly forms plasma separation chambeies 14 with cup 8 between the two.
In the present embodiment, the outside dimension of cup nuclear core 18 is 30mm, and the disengagement chamber volume is 340ml.
All the other are identical with embodiment 1.
The above description of doing in conjunction with the utility model embodiment does not consist of any restriction to protection scope of the present invention.Those skilled in the art can make various changes on basis of the present invention, and these change all should think and fall within the protection domain that claim of the present invention limits.

Claims (2)

1. large capacity plasma separation cup, comprise static head (1), obturating cup (2), sealing gasket (3), sealing ring (4), bowl cover (5), upper cover (6), lower cover (7), cup (8), cup nuclear (9), central tube (10), cup nuclear is connected with cup, it is characterized in that cup nuclear (9) is compound cup nuclear, this compound cup nuclear (9) is by retainer ring (15), cup nuclear core (18), positioning disk (20) consists of, retainer ring (15) welds by pad (16) with cup nuclear core (18), blood plasma is arranged between the two, haemocyte overflow seam (17), cup nuclear core (18) welds by pad (19) with positioning disk (20), jointly forms plasma separation chamber (14) with cup (8) between the two.
2. large capacity plasma separation cup according to claim 1 is characterized in that the outside dimension of cup nuclear core (18) is 22-35mm.
CN 201220502470 2012-09-28 2012-09-28 High-capacity plasma separation cup Expired - Lifetime CN202892981U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201220502470 CN202892981U (en) 2012-09-28 2012-09-28 High-capacity plasma separation cup

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201220502470 CN202892981U (en) 2012-09-28 2012-09-28 High-capacity plasma separation cup

Publications (1)

Publication Number Publication Date
CN202892981U true CN202892981U (en) 2013-04-24

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CN 201220502470 Expired - Lifetime CN202892981U (en) 2012-09-28 2012-09-28 High-capacity plasma separation cup

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108144142A (en) * 2018-01-18 2018-06-12 董亚东 A kind of centrifugal type blood composition separate cup and separation method
CN109395893A (en) * 2018-11-30 2019-03-01 江苏伯纳德生物科技发展有限公司 A kind of cup type centrifugal device being suitable for different disposal blood volume
CN109568690A (en) * 2019-01-31 2019-04-05 中国人民解放军陆军军医大学第附属医院 Disposable acquisition whole blood separation PRP filters Leukapheresis devices

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108144142A (en) * 2018-01-18 2018-06-12 董亚东 A kind of centrifugal type blood composition separate cup and separation method
CN109395893A (en) * 2018-11-30 2019-03-01 江苏伯纳德生物科技发展有限公司 A kind of cup type centrifugal device being suitable for different disposal blood volume
CN109568690A (en) * 2019-01-31 2019-04-05 中国人民解放军陆军军医大学第附属医院 Disposable acquisition whole blood separation PRP filters Leukapheresis devices
CN109568690B (en) * 2019-01-31 2021-04-09 中国人民解放军陆军军医大学第一附属医院 Disposable whole blood collection PRP leukocyte filtering device

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Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20131202

Address after: 641403 Ziyang City, Sichuan province Jianyang City Dongxi town Kui Xing Lu No. 28

Patentee after: SICHUAN NIGALE BIOTECHNOLOGY Co.,Ltd.

Address before: High tech Zone Chengdu city Sichuan Province Jincheng Road 610041 No. 825 2 3 storey building No. 306

Patentee before: Sichuan Nigale Biomedical Co.,Ltd.

CX01 Expiry of patent term

Granted publication date: 20130424

CX01 Expiry of patent term