CN202892421U - 游离循环dna采集容器 - Google Patents
游离循环dna采集容器 Download PDFInfo
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- CN202892421U CN202892421U CN 201220325653 CN201220325653U CN202892421U CN 202892421 U CN202892421 U CN 202892421U CN 201220325653 CN201220325653 CN 201220325653 CN 201220325653 U CN201220325653 U CN 201220325653U CN 202892421 U CN202892421 U CN 202892421U
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- 102000053602 DNA Human genes 0.000 title abstract 11
- 108020004414 DNA Proteins 0.000 title abstract 11
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- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract description 9
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Abstract
本实用新型是一种DNA采集容器,特别是一种游离循环DNA采集容器。其包括一容器,容器上设有胶塞,胶塞的外面设有保护帽,容器内设有添加剂,添加剂由甲醛缓释剂、抗凝剂和细胞稳定剂组成;所述容器为试管或瓶子;所述容器为非真空状态或为真空状态;所述容器为玻璃或塑料材质。本实用新型设有添加剂,添加剂能维持样本本体细胞不破裂,即样本中不产生新的DNA而干扰游离循环DNA,对血液等样本又有抗凝血作用,同时可防止样本腐败变质,使样本能在一般条件下保持长期使用;本实用新型可制作成真空采集容器,使操作更加简便且避免医源性感染;本实用新型可以使产前诊断和肿瘤早期诊断及相应疾病诊断实现无创性采样。
Description
技术领域
本实用新型是一种DNA采集容器,特别是一种游离循环DNA采集容器。
背景技术
游离循环DNA是一种细胞外游离状态的DNA,主要由单链或双链或单双链混合物组成,以DNA-蛋白质复合物或游离DNA形式存在。目前已经在外周血浆、血清、尿液、前列腺液、唾液、脑脊液、淋巴液、腹腔液、胃液、胆汁及粪便中检测到游离循环DNA的存在。游离循环DNA是产前胎儿诊断和肿瘤早期诊断及存活率判断的基础,同时还可以应用到外伤、中风、糖尿病及自身性免疫疾病等领域。
由于游离循环DNA相对于本体DNA,其含量极少,这就对游离循环DNA的采集提出很高的要求。目前临床及科研单位一般是用注射器或普通试管采集游离循环DNA,其技术相对落后,不能保证采集的数量和质量,而且采集样本后需要特殊条件保存(如冷藏、冰浴等),无法满足临床及科研需要。
发明内容
本实用新型的目的是为了克服现有用注射器或普通试管采集游离循环DNA不能确保采集数量和质量的缺陷,发明一种有抗凝血作用可防止样本腐败变质的游离循环DNA采集容器。
本实用新型的目的是按如下的方式来实现的:所述游离循环DNA采集容器,包括一容器,容器上设有胶塞,胶塞的外面设有保护帽,容器内设有添加剂,添加剂由甲醛缓释剂、抗凝剂和细胞稳定剂组成。
所述容器为试管或瓶子。
所述容器为非真空状态或为真空状态。
所述容器为玻璃或塑料材质。
本实用新型的积极效果如下:本实用新型设有添加剂,添加剂能维持样本本体细胞不破裂,即样本中不产生新的DNA而干扰游离循环DNA,对血液等样本又有抗凝血作用,同时可防止样本腐败变质,使样本能在一般条件下保持长期使用;本实用新型可制作成真空采集容器,使操作更加简便且避免医源性感染;本实用新型可以使产前诊断和肿瘤早期诊断及相应疾病诊断实现无创性采样;本实用新型应用范围广,可应用于孕妇产前诊断及胚胎医学研究、肿瘤早期诊断及预后判断、外伤、中风、糖尿病及自身性免疫疾病等领域。
附图说明
图1是本实用新型第一实施例结构图
图2是本实用新型第二实施例结构图
图中:1容器 2胶塞 3保护帽
4添加剂
具体实施方式
如图1图2所示,所述游离循环DNA采集容器,包括一容器1,容器1上设有胶塞2,胶塞2的外面设有保护帽3,容器1内设有添加剂4,添加剂4由甲醛缓释剂、抗凝剂和细胞稳定剂组成。
所述容器1为试管或瓶子。
所述容器1为非真空状态或为真空状态。
所述容器1为玻璃或塑料材质。
使用时,非真空的采集容器需借助注射器、采血针及其他助器等器具辅助采集,二真空状态的采集容器,可以利用真空抽取样本(如外周血液、尿液、腹腔液等),然后通过后续的工作程序富集游离循环DNA。
Claims (4)
1.一种游离循环DNA采集容器,其特征在于:其包括一容器,容器上设有胶塞,胶塞的外面设有保护帽,容器内设有添加剂。
2.根据权利要求1所述的游离循环DNA采集容器,其特征在于:所述容器为试管或瓶子。
3.根据权利要求1所述的游离循环DNA采集容器,其特征在于:所述容器为非真空状态或为真空状态。
4.根据权利要求1所述的游离循环DNA采集容器,其特征在于:所述容器为玻璃或塑料材质。
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104673623A (zh) * | 2015-02-05 | 2015-06-03 | 广州新诚生物科技有限公司 | 血液样品收集装置 |
CN105985904A (zh) * | 2015-02-26 | 2016-10-05 | 付士明 | 循环游离dna真空采集管 |
-
2012
- 2012-07-06 CN CN 201220325653 patent/CN202892421U/zh not_active Expired - Lifetime
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104673623A (zh) * | 2015-02-05 | 2015-06-03 | 广州新诚生物科技有限公司 | 血液样品收集装置 |
CN105985904A (zh) * | 2015-02-26 | 2016-10-05 | 付士明 | 循环游离dna真空采集管 |
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