CN202837188U - Portable optical fiber surface enhanced Raman scattering spectrometer - Google Patents
Portable optical fiber surface enhanced Raman scattering spectrometer Download PDFInfo
- Publication number
- CN202837188U CN202837188U CN 201220270485 CN201220270485U CN202837188U CN 202837188 U CN202837188 U CN 202837188U CN 201220270485 CN201220270485 CN 201220270485 CN 201220270485 U CN201220270485 U CN 201220270485U CN 202837188 U CN202837188 U CN 202837188U
- Authority
- CN
- China
- Prior art keywords
- optical fiber
- fiber
- raman
- portable
- light path
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Abstract
The utility model discloses a portable optical fiber surface enhanced Raman scattering (SERS) spectrometer which comprises a Raman spectrometer body. The spectrometer body is connected with an optrode for exciting laser and collecting sample Raman spectrum signal light, and the optrode is formed by enabling a surface enhanced activity substrate to be directly constructed at the end of an optical fiber. The portable Raman spectrometer and the optrode enabling the surface enhanced activity substrate to be directly constructed at one end of the optical fiber are integrated. Due to the fact that the requirements of the optical fiber forming the optrode for sample preparation and an instrument light path are low, the portable optical fiber SERS spectrometer is low cost, the shortcomings that the conventional SERS analysis sample preparation process is complex, the reproducibility is poor and the cost is high are overcome, the optical fiber SERS spectrometer has the advantage of being portable, ultrahigh-sensitivity instant testing and display analysis can be achieved in on-site analysis, and qualitative and quantitative results can be provided for micro and trace-amount samples. Popularization of the portable optical fiber SERS spectrometer is of great significance to the fields of homeland security, environmental monitoring, food safety and medical health.
Description
Technical field
The utility model relates to the Surface enhanced raman spectroscopy technology, particularly utilizes optical fiber as the portable fiber-optic surface-enhanced Raman spectroscopy of the substrate of Surface enhanced raman spectroscopy.
Background technology
Surface enhanced raman spectroscopy (Surface Enhanced Raman Scattering, SERS) is a kind of emerging molecular vibration spectrum analytical technology.Because vibrational spectrum is the fingerprint of material molecule, SERS can be used for accurate qualitative discriminating sample.SERS has the sensitivity for analysis of superelevation, and more common Raman analysis sensitivity improves about 10 orders of magnitude, can analyze the little molecule that arrives, and arrives greatly the research object of cellular level.Be that the SERS technology is a kind ofly can carry out simultaneously the qualitative and quantitative analysis technology to trace and ultratrace sample, have very widely application prospect.
Substrate is considered to the SERS technology is applied to scene and remote sensing analysis the most reliably and one of mode of application prospect is arranged most as SERS to utilize optical fiber.Technology (Gustavo F.S.Andrade formerly, Meikun Fan, Alexandre G.Brolo.Multilayer silver nanoparticles-modified optical fiber tip for high performance SERS remote sensing, Biosensors and bioelectronics 25,2010,2270-2275) with light source, spectrometer and optical fiber substrate are carried out coupled transfer by microscope and space optical path.Coupled structure in this scheme between optical fiber substrate and microscope is complicated, is difficult to use in scene and remote sensing analysis.In addition, formerly technology is not carried out the self-assembled film modification to the auroral poles surface, so that the object of auroral poles analytical applications is limited.
And existing portable normal Raman spectroscopy instrument designs mainly for macro-analysis, these instruments are expensive, most critical be not have supporting high reliability SERS active substrate (substrate), utilize this instrument to carry out SERS and analyze common need to use gold or silver nano-particle solution, not only complicated operation but also reappearance are low, are not suitable for quantitative test.Therefore, this equipment can't satisfy the requirement of on-the-spot trace and ultratrace qualitative and quantitative analysis.
Therefore, need a kind of portable fiber-optic surface-enhanced Raman spectroscopy, avoid conventional Surface enhanced raman spectroscopy (SERS) to analyze the loaded down with trivial details weakness of sample making course, advantage with Portable Raman spectrometer, realize in can analyzing at the scene that it is display analysis that hypersensitivity is namely surveyed, and can provide the qualitative, quantitative result to trace and trace samplings; This is to Homeland Security, environmental monitoring, and food security and medicine and hygiene fields are of great significance.
The utility model content
In view of this, the purpose of this utility model provides a kind of portable fiber-optic surface-enhanced Raman spectroscopy, avoid conventional Surface enhanced raman spectroscopy (SERS) to analyze the loaded down with trivial details weakness of sample making course, advantage with Portable Raman spectrometer, realize in can analyzing at the scene that it is display analysis that hypersensitivity is namely surveyed, and can provide the qualitative, quantitative result to trace and trace samplings, to Homeland Security, environmental monitoring, food security and medicine and hygiene fields are of great significance.
Portable fiber-optic surface-enhanced Raman spectroscopy of the present utility model, comprise the Raman spectrometer body, described spectrometer body is connected with for the auroral poles that also is used for collected specimens raman spectral signal light by excitation laser, and described auroral poles is formed in optical fiber end by surperficial enhanced activity substrate direct construction.
Further, the surperficial enhanced activity substrate of described auroral poles is made of the self-assembled nanometer material layer more than one deck;
Further, outermost self-assembled nanometer material layer outside surface is modified with for separating of enrichment and identification sample self assembly molecule film;
Further, the Raman spectrometer body comprises excitation laser light path and raman spectral signal light path, and the excitation laser light path is connected the coupling of one 1 * 2 fiber optic splitters and is connected by auroral poles optical fiber with auroral poles with the raman spectral signal light path;
Further, the raman spectral signal of described raman spectral signal light path is inputted a central processing unit by ccd sensor;
Further, described excitation laser light path and raman spectral signal light path are arranged in the housing, and described 1 * 2 fiber optic splitter is connected by joints of optical fibre are detachable with auroral poles optical fiber, and these joints of optical fibre expose to housing with the interface that auroral poles optical fiber is connected;
Further, described central processing unit is one to store the computing machine of many kinds of substance SERS spectra database; Pass through data line or wireless connections between described computing machine and the Raman spectrometer body;
Further, the excitation laser light path comprise LASER Light Source and be connected in LASER Light Source and 1 * 2 fiber optic splitter between excitation laser optical fiber, described raman spectral signal light path comprises raman spectral signal optical fiber and the light treatment facility that is connected with 1 * 2 fiber optic splitter.
The beneficial effects of the utility model: portable fiber-optic surface-enhanced Raman spectroscopy of the present utility model, make the Portable Raman spectrometer body and SERS active substrate direct construction is integrated at the auroral poles that optical fiber one end forms, optical fiber is born transmission excitation laser and SERS signal simultaneously, because it is extremely low to the requirement of sample preparation and instrument light path to consist of the optical fiber of auroral poles, has lower cost, thereby avoid conventional Surface enhanced raman spectroscopy (SERS) to analyze the shortcoming that sample making course is loaded down with trivial details and cost is higher, so that the utlity model has the advantage of Portable Raman spectrometer, realize in can analyzing at the scene that it is display analysis that hypersensitivity is namely surveyed, can provide the qualitative, quantitative result to trace and trace samplings, to Homeland Security, environmental monitoring, food security and medicine and hygiene fields are of great significance.
Description of drawings
Below in conjunction with drawings and Examples the utility model is further described.
Fig. 1 is structural principle synoptic diagram of the present utility model;
Fig. 2 is the auroral poles structural representation.
Embodiment
Fig. 1 is structural principle synoptic diagram of the present utility model, as shown in the figure: the portable fiber-optic surface-enhanced Raman spectroscopy of present embodiment, comprise Raman spectrometer body 1, described spectrometer body 1 is connected with for the auroral poles 16 that also is used for collected specimens raman spectral signal light 17 by excitation laser 18, and described auroral poles 16 is formed in optical fiber end by surperficial enhanced activity substrate direct construction; As shown in the figure, auroral poles 16 is positioned at sample 15, and excitation laser 18 and sample raman spectral signal light 17 are by auroral poles 16.
In the present embodiment, the surperficial enhanced activity substrate of described auroral poles 16 is made of the self-assembled nanometer material layer more than one deck; Utilize optical fiber as the carrier of SERS substrate, self assembly has the nano materials such as gold, silver, copper on it;
In the present embodiment, outermost self-assembled nanometer material layer outside surface is modified with for separating of enrichment and identification sample self assembly molecule film 16a; During making, make it have separation and concentration and interior reference function concurrently, form the SERS auroral poles of supporting high sensitivity and high reliability.
In the present embodiment, described Raman spectrometer body 1 comprises excitation laser light path and raman spectral signal light path, and the excitation laser light path is connected 12 couplings of one 1 * 2 fiber optic splitters and is connected by auroral poles optical fiber 14 with auroral poles 16 with the raman spectral signal light path; Simple and compact for structure, auroral poles optical fiber 14 is born transmission excitation laser and SERS signal simultaneously; The SERS auroral poles is extremely low to the requirement of sample preparation (sampling) and instrument light path, and cheapness can abandon, and has greatly reduced cost.
In the present embodiment, the raman spectral signal of described raman spectral signal light path is by ccd sensor 2 inputs one central processing unit 19; Central processing unit 19 can be the data processing equipments such as main frame and single-chip microcomputer.
In the present embodiment, described excitation laser light path and raman spectral signal light path are arranged in the housing 20, described 1 * 2 fiber optic splitter 12 and auroral poles optical fiber 14 are by 13 detachable connections of joints of optical fibre, and the interface that these joints of optical fibre 13 are connected with auroral poles optical fiber 14 exposes to housing 20; Easy to use, more meet the portable advantage that the utility model has.
In the present embodiment, described central processing unit 19 is the computing machine that a storage surface strengthens the Raman spectrum data storehouse; By data line or wireless connections, present embodiment adopts data line between described computing machine and the Raman spectrometer body 1; From now on, can according to the SERS spectra database of setting up, set up the intelligent on-line search method to realize qualitatively requirement of unknown material; The SERS spectra database will help to use native system and carry out qualitative to trace and ultratrace sample.
In the present embodiment, the excitation laser light path comprise LASER Light Source 9 and be connected in LASER Light Source 9 and 1 * 2 fiber optic splitter 12 between excitation laser optical fiber 10, described raman spectral signal light path comprises raman spectral signal optical fiber 11 and the light treatment facility that is connected with 1 * 2 fiber optic splitter 12, between light source, substrate and spectrometer body, adopt full optical fiber to be connected, further be beneficial to on-the-spot use and remote sensing analysis; As shown in the figure, the light treatment facility comprises slit 7, collimating mirror 6, filter plate 5, reflection grating 8, object lens 4 and the catoptron 3 that raman spectral signal light 17 is passed through successively, carry out the processing such as a series of diffraction, collimation, the raman spectral signal light input ccd sensor 2 after catoptron 3 will be processed.
Explanation is at last, above embodiment is only unrestricted in order to the technical solution of the utility model to be described, although with reference to preferred embodiment the utility model is had been described in detail, those of ordinary skill in the art is to be understood that, can make amendment or be equal to replacement the technical solution of the utility model, and not breaking away from aim and the scope of technical solutions of the utility model, it all should be encompassed in the middle of the claim scope of the present utility model.
Claims (8)
1. portable fiber-optic surface-enhanced Raman spectroscopy, it is characterized in that: comprise the Raman spectrometer body, described spectrometer body is connected with for the auroral poles that also is used for collected specimens raman spectral signal light by excitation laser, and described auroral poles is formed in optical fiber end by surperficial enhanced activity substrate direct construction.
2. portable fiber-optic surface-enhanced Raman spectroscopy according to claim 1, it is characterized in that: the surperficial enhanced activity substrate of described auroral poles is made of the self-assembled nanometer material layer more than one deck.
3. portable fiber-optic surface-enhanced Raman spectroscopy according to claim 2 is characterized in that: outermost self-assembled nanometer material layer outside surface is modified with for separating of enrichment and identification sample self assembly molecule film.
4. portable fiber-optic surface-enhanced Raman spectroscopy according to claim 3, it is characterized in that: the Raman spectrometer body comprises excitation laser light path and raman spectral signal light path, and the excitation laser light path is connected the coupling of one 1 * 2 fiber optic splitters and is connected by auroral poles optical fiber with auroral poles with the raman spectral signal light path.
5. portable fiber-optic surface-enhanced Raman spectroscopy according to claim 4, it is characterized in that: the raman spectral signal of described raman spectral signal light path is inputted a central processing unit by ccd sensor.
6. portable fiber-optic surface-enhanced Raman spectroscopy according to claim 5, it is characterized in that: described excitation laser light path and raman spectral signal light path are arranged in the housing, described 1 * 2 fiber optic splitter is connected by joints of optical fibre are detachable with auroral poles optical fiber, and these joints of optical fibre expose to housing with the interface that auroral poles optical fiber is connected.
7. portable fiber-optic surface-enhanced Raman spectroscopy according to claim 6 is characterized in that: described central processing unit is one to store the computing machine of SERS spectra database; Pass through data line or wireless connections between described computing machine and the Raman spectrometer body.
8. portable fiber-optic surface-enhanced Raman spectroscopy according to claim 7, it is characterized in that: the excitation laser light path comprise LASER Light Source and be connected in LASER Light Source and 1 * 2 fiber optic splitter between excitation laser optical fiber, described raman spectral signal light path comprises raman spectral signal optical fiber and the light treatment facility that is connected with 1 * 2 fiber optic splitter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220270485 CN202837188U (en) | 2012-06-08 | 2012-06-08 | Portable optical fiber surface enhanced Raman scattering spectrometer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220270485 CN202837188U (en) | 2012-06-08 | 2012-06-08 | Portable optical fiber surface enhanced Raman scattering spectrometer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202837188U true CN202837188U (en) | 2013-03-27 |
Family
ID=47948868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220270485 Expired - Fee Related CN202837188U (en) | 2012-06-08 | 2012-06-08 | Portable optical fiber surface enhanced Raman scattering spectrometer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202837188U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104267020A (en) * | 2014-10-28 | 2015-01-07 | 首都师范大学 | Optical fiber raman radar and design method thereof |
| CN104458700A (en) * | 2014-12-11 | 2015-03-25 | 成都鼎智汇科技有限公司 | Portable chemical composition remote analysis device based on Raman spectrum |
| CN104865279A (en) * | 2014-02-26 | 2015-08-26 | 清华大学 | Customs supervision item rapid-inspection equipment and method |
| CN114965435A (en) * | 2022-06-15 | 2022-08-30 | 中验科技(福建)有限公司 | Enhanced Raman spectrometer for on-site drug monitoring and use method thereof |
-
2012
- 2012-06-08 CN CN 201220270485 patent/CN202837188U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104865279A (en) * | 2014-02-26 | 2015-08-26 | 清华大学 | Customs supervision item rapid-inspection equipment and method |
| CN104267020A (en) * | 2014-10-28 | 2015-01-07 | 首都师范大学 | Optical fiber raman radar and design method thereof |
| CN104458700A (en) * | 2014-12-11 | 2015-03-25 | 成都鼎智汇科技有限公司 | Portable chemical composition remote analysis device based on Raman spectrum |
| CN114965435A (en) * | 2022-06-15 | 2022-08-30 | 中验科技(福建)有限公司 | Enhanced Raman spectrometer for on-site drug monitoring and use method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101514964B (en) | A material detector based on Raman spectroscopy | |
| Mu et al. | Detection of pesticide residues using nano-SERS chip and a smartphone-based Raman sensor | |
| CN101666750B (en) | Surface-enhanced raman scattering sensor detector based on optical fiber fuse-tapered coupler | |
| CN202837188U (en) | Portable optical fiber surface enhanced Raman scattering spectrometer | |
| CN101561396B (en) | Bi-conical tapered fiber evanescent wave coupling-based fiber Raman sensor detection device | |
| CN103376251A (en) | Portable Raman spectrum measuring device and system for quickly detecting article | |
| CN103674902A (en) | LSPR (Localized Surface Plasmon Resonance) portable biochemical detector based on mobile phone platform | |
| CN202442964U (en) | Portable optical fiber surface-enhanced Raman spectrometer | |
| CN102980658A (en) | Micro optical fiber spectrograph | |
| CN202916200U (en) | Medical fluorescent quantitation analysis meter | |
| CN101514985A (en) | Local surface plasma resonance reinforced biochemical detector | |
| CN102564983A (en) | Optical detection device and method for concentration of components in turbid medium based on limited range wavelength method | |
| CN107290314B (en) | Fluorescence detection method and device for unmarked micro-nano particles | |
| Huck | Recent developments in solid-phase extraction for near and attenuated total reflection infrared spectroscopic analysis | |
| CN104267016A (en) | In-vivo drug testing system based on nanoparticle modified hollow-core optical fiber | |
| CN1546987A (en) | Minitype biochemical spectrum analyzer | |
| Artemyev et al. | Blood proteins analysis by Raman spectroscopy method | |
| CN2819244Y (en) | Beam splitting system of laser inductive wave fluorescent pollution monitor | |
| CN106880338A (en) | Neoplasm in situ on-line detecting system based on SERS technology | |
| CN102636462B (en) | On-line purified multimode conduction surface plasma resonance spectrometer | |
| CN207908362U (en) | A kind of full-automatic haldane-Henderson gas analysis apparatus based on cavity ring down spectroscopy technology | |
| CN102252983A (en) | Deep ultraviolet spectrum measurement and spectrophotometry measurement device | |
| CN205719962U (en) | A kind of humidity tester using laser | |
| CN103604768A (en) | Portable UV spectrophotometer special for CO poisoning and application method thereof | |
| CN218766627U (en) | Petroleum property analysis system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130327 Termination date: 20130608 |