CN202766540U

CN202766540U - Novel L-methionine production device

Info

Publication number: CN202766540U
Application number: CN2012204892199U
Authority: CN
Inventors: 不公告发明人
Original assignee: XINYI HANLING BIO-ENGINEERING Co Ltd
Current assignee: XINYI HANLING BIO-ENGINEERING Co Ltd
Priority date: 2012-09-25
Filing date: 2012-09-25
Publication date: 2013-03-06
Anticipated expiration: 2022-09-25

Abstract

The utility model discloses a novel L-methionine production device, and belongs to the field of amino acid production. The device comprises a first reaction kettle, a crystallization kettle, a centrifuge, a concentration tank, a resolution kettle, a second reaction kettle, a refining neutralization kettle, a dryer and a crusher, a first rotary piston pump and a pipeline are arranged between the first reaction kettle and the crystallization kettle, a second rotary piston pump and a pipeline are arranged between the crystallization kettle and the centrifuge, a third rotary piston pump and a pipeline are arranged between the centrifuge and the concentration tank, a fourth rotary piston pump and a pipeline are arranged between the concentration tank and the crystallization kettle, a first conveyor is arranged between the centrifuge and the resolution kettle, a fifth rotary piston pump and a pipeline are arranged between the resolution kettle and the second reaction kettle, a sixth rotary piston pump and a pipeline are arranged between the second reaction kettle and the refining neutralization kettle, a second conveyor is arranged between the refining neutralization kettle and the dryer, a third conveyor is arranged between the dryer and the crusher, and a finished product outlet is arranged on the crusher.

Description

Novel L-Methionine production equipment

Technical field:

The utility model belongs to the amino acids production field, relates in particular to a kind of new device of producing L-Methionine.

Background technology:

Methionine(Met), molecular formula is C5H11NO2S, formal name used at school methylthio group Gamma Amino Butyric Acid, outward appearance is the crystallization of white flakes shape or powder, slightly is with special odor, mildly bitter flavor, it is one of component of protein, also being the indispensable amino acid of human body, is the amino acid of unique sulfur-bearing in the essential amino acid, minute levo form L-Methionine and dextrorotatory form D-methionine(Met).Water-soluble and the warm Diluted Alcohol of L-Methionine is insoluble to dehydrated alcohol, ether, sherwood oil, benzene, acetone, and its pH value of water solution of 10% is 5.6-6.1, and is to heat and air-stable, unstable to strong acid.L-Methionine is the essential amino acid of sulfur-bearing, when lacking L-Methionine in the organism, can cause appetite stimulator, growth slow down or do not put on weight, the phenomenons such as kidney enlargement and the accumulation of liver iron, cause at last hepatic necrosis or fibrosis.The main application of L-Methionine is: 1. aspect medical, L-Methionine can be used for preventing and treating the chronic or hepatic diseases such as acute hepatitis, liver cirrhosis, also can be used for alleviating the toxic reaction of the objectionable impuritiess such as arsenic, trichloromethane, tetracol phenixin, benzene, pyridine and quinoline; L-Methionine is one of main component of amino acid transfusion and aminoacids complex, can be used for the synthetic drug VITAMIN; L-Methionine plays provide protection to the heart, brain, kidney etc., and is irritated also helpful with osteoporosis to chemistry, if lack methionine(Met) in the body, also can affect the function that human body is made urine, and cause oedema.At the food service industry L-Methionine as accessory substance, be used for the processing of food and fresh-keeping product.3. on fodder industry, L-Methionine is a kind of requisite additive in the animal-feed, and the animal-feed that is added with L-Methionine can help the animal Fast Growth at short notice, makes it save about 40% feed.The utility model device be a kind of with DL-methionine as main raw material, with the first reactor, crystallization kettle, whizzer, concentration tank, split still, the second reactor, in refining and still, dryer, pulverizer is equipment, by producing first N-acetyl-DL-methionine, then carry out solid-liquid separation by whizzer, carry out again enzyme digestion reaction, reduction reaction obtains the L-Methionine crude product, can obtain the L-Methionine finished product after the L-Methionine crude product made with extra care, the advantage of this device is: the equipment of use be produce the amino acid general-purpose equipment and production efficiency high, technique is simple, raw material sources are convenient, pollution-free waste discharge, the series of advantages such as good product quality.

Summary of the invention:

The problem that the utility model mainly solves provides a kind of mechanism of producing L-Methionine, this device is with the first reactor, crystallization kettle, whizzer, concentration tank, split still, the second reactor, in refining and still, dryer, pulverizer is equipment, with DL-methionine, aceticanhydride, liquid caustic soda, hydrochloric acid, the enzymatic reaction catalyzer, pure water, gac is that raw material is produced L-Methionine, this device forms by producing the amino acid general-purpose equipment, has rational in infrastructure, production technique is simple, the production process mild condition, pollution-free waste discharge, the series of advantages such as good product quality.

The technical solution adopted in the utility model is:

A kind of new device of producing L-Methionine comprises: the first reactor 1, crystallization kettle 2, whizzer 3, concentration tank 4, split still 5, the second reactor 6, refining in and still 7, dryer 8, pulverizer 9; The first reactor 1 is provided with liquid caustic soda import 10, purified water inlet 11, DL-methionine import 12, aceticanhydride import 13, steam inlet 14, the first reactor 1 is provided with the first rotopiston pump and pipeline 15 to 2 of crystallization kettles, crystallization kettle 2 is provided with hydrochloric acid import 16, circulating cooling salt water inlet 17, crystallization kettle 2 is provided with the second rotopiston pump and pipeline 18 to 3 in whizzer, whizzer 3 is provided with the 3rd rotopiston pump and pipeline 19 to 4 of concentration tanks, concentration tank 4 is provided with the 4th rotopiston pump and pipeline 20 to 2 of crystallization kettles, whizzer 3 is provided with the first transfer roller 21 to splitting 5 of stills, split still 5 and be provided with purified water inlet 22, hydrochloric acid import 23, enzymatic reaction catalyst inlet 24, liquid

caustic soda import

25,6 of fractionation still 5 to second reactors are provided with the 5th rotopiston pump and pipeline 26, the second reactors 6 are provided with purified water inlet 27, steam inlet 28, gac import 29, the second reactor 6 in refining and 7 of stills be provided with the 6th rotopiston pump and pipeline 30, refining in and still 7 be provided with circulating cooling salt water inlet 31, refining in and still 7 be provided with second conveyor 32 to 8 of dryers, dryer 8 is provided with the 3rd transfer roller 33 to 9 in pulverizer, and pulverizer 9 is provided with product outlet 34.

Further technical scheme of the present utility model is:

Described whole rotopiston pump is stainless steel, all pipeline is the polyethylene material.

Described whole transfer roller is scraper conveyor.

The beneficial effects of the utility model are: a kind of new device of producing L-Methionine is provided, this device uses produces the amino acid general-purpose equipment, have the series of advantages such as simple in structure, easy to operate, production process mild condition, pollution-free waste discharge, good product quality, the product L-Methionine is mainly as using as pharmaceutical preparation, accessory substance, fodder additives.

Description of drawings:

Be structure iron of the present utility model such as Fig. 1.

Embodiment

Embodiment:

Further specify the particular content that uses this new device to produce the L-Methionine most preferred embodiment below in conjunction with accompanying drawing:

(1) with the liquid caustic soda of formula ratio; pure water; DL-methionine is by being arranged at the import 10 on the first reactor 1; 11; 12 send into the first reactor 1; to be evacuated to vacuum after 1 sealing of the first reactor; the aceticanhydride of formula ratio is sent into the first reactor 1 by the import 13 that is arranged on the first reactor 1; the interlayer of while stirring steam being sent into the first reactor 1 by the import 14 on the first reactor 1 heats up; under the condition of sealing so that mixing liquid is little in the still boils; keep temperature-resistant; used the slow stirring reaction of stirrer 12 hours; make the DL-methionine acetylize; reaction is sent into crystallization kettle 2 by being arranged at the first reactor 1 to the first rotopiston pump and first pipeline 15 of 2 of crystallization kettles with reaction solution after finishing.

(2) hydrochloric acid is sent into crystallization kettle 2 by the import 16 that is arranged on the crystallization kettle 2, while stirring the reaction solution in the crystallization kettle 2 is neutralized, the pH value of transferring reaction solution is to stop to add hydrochloric acid at 6 o'clock, at this moment the interlayer of by the import 17 that is arranged on the crystallization kettle 2 circulating cooling salt solution being sent into crystallization kettle 2 is lowered the temperature, temperature in the crystallization control still 2 is 0 ℃-3 ℃, under this temperature, slowly stir crystallization in 12 hours, after crystallization is complete all materials are sent into whizzer 3 elimination liquid by the second rotopiston pump and the pipeline 18 that are arranged at 3 in crystallization kettle 2 and whizzer, obtain first xln; Filter the liquid that obtains and send into concentration tank 4 by the 3rd rotopiston pump and the pipeline 19 that are arranged at 4 of whizzer 3 and concentration tanks, send into crystallization kettle 2 crystallisation by cooling 12 hours by the 4th rotopiston pump and the pipeline 20 that are arranged at 2 of concentration tank 4 and crystallization kettles after being concentrated into half of volume, the crystallization that obtains is sent into immediately whizzer 3 and is carried out solid-liquid separation and obtain the second batch xln, and first and second batch xln are merged.

(3) xln after will merging is sent into by the first transfer roller 21 that is arranged at whizzer 3 and splits 5 of stills and is split still 5, be that the pure water of 5 times on xln is sent into and split still 5 by being arranged at the import 22 that splits on the still 5 with weight, after the stirring xln is all dissolved, add appropriate hydrochloric acid by import 23, adjust pH is to stop acid adding at 4 o'clock, use constant temperature system to control this feed temperature between 35 ℃-40 ℃, add the enzymatic reaction catalyzer that accounts for xln quantity 1% by import 24, the rear standing and reacting that stirs 30 hours, reaction finishes rear the adding by import 25 and stops temperature control after an amount of liquid caustic soda is transferred pH value to 5.5, allow its naturally cooling and stirred crystallization, obtain the L-Methionine crude product.

(4) the L-Methionine crude product is sent into the second reactor 6 by the 5th rotopiston pump and the pipeline 26 that are arranged at 6 of fractionation still 5 and the second reactors, by sending into steam intensification stirring and dissolving by import 28 behind the pure water that is arranged at the 10 times of weight of import 27 adding L-Methionine crude products on the second reactor 6, adding weight by import 29 when being heated to 70 ℃ is the gac of L-Methionine crude product 1%, constant temperature stirs decolouring and obtained clear liquid in 0.5 hour, with the clear liquid that obtains by be arranged at the second reactor 6 and refining in and the 6th rotopiston pump of 7 of stills and pipeline 30 send into refining in and still 7, clear liquid is through behind the naturally cooling, by be arranged at refining in and import 31 on the still 7 in refining and the interlayer of still 7 send into circulating cooling salt solution, when being cooled to 0-3 ℃, constant temperature keeps crystallization in 12 hours, crystallisate after the crystallization by be arranged at refining in and the second conveyor 32 of 8 of still 7 and dryers send in the dryer and dry, bake out temperature is 44 ℃-50 ℃, drying time is 5-6 hour, wraps into the storehouse and gets final product by being arranged at outlet 34 dischargings dress on the pulverizer 9 after the caking thing after then will drying is sent into pulverizer 9 and pulverized by the 3rd transfer roller 33 that is arranged at 9 in dryer 8 and pulverizer.

Claims

1. novel L-Methionine production equipment is characterized in that: comprise the first reactor (1), crystallization kettle (2), whizzer (3), concentration tank (4), split still (5), the second reactor (6), refining in and still (7), dryer (8), pulverizer (9); The first reactor (1) is provided with liquid caustic soda import (10), purified water inlet (11), DL-methionine import (12), aceticanhydride import (13), steam inlet (14), the first reactor (1) is to being provided with the first rotopiston pump and pipeline (15) between crystallization kettle (2), crystallization kettle (2) is provided with hydrochloric acid import (16), circulating cooling salt water inlet (17), crystallization kettle (2) is to being provided with the second rotopiston pump and pipeline (18) between whizzer (3), whizzer (3) is to being provided with the 3rd rotopiston pump and pipeline (19) between concentration tank (4), concentration tank (4) is to being provided with the 4th rotopiston pump and pipeline (20) between crystallization kettle (2), whizzer (3) is provided with the first transfer roller (21) to splitting between still (5), split still (5) and be provided with purified water inlet (22), hydrochloric acid import (23), enzymatic reaction catalyst inlet (24), liquid caustic soda import (25), split still (5) to being provided with the 5th rotopiston pump and pipeline (26) between the second reactor (6), the second reactor (6) is provided with purified water inlet (27), steam inlet (28), gac import (29), the second reactor (6) is in refining and be provided with the 6th rotopiston pump and pipeline (30) between still (7), in refining and still (7) be provided with circulating cooling salt water inlet (31), in refining and still (7) be provided with second conveyor (32) between dryer (8), dryer (8) is provided with the 3rd transfer roller (33) between pulverizer (9), and pulverizer (9) is provided with product outlet (34).

2. a kind of novel L-Methionine production equipment according to claim 1 is characterized in that: described whole rotopiston pumps are stainless steel, all pipeline is the polyethylene material.

3. a kind of novel L-Methionine production equipment according to claim 1, it is characterized in that: described whole transfer rollers are scraper conveyor.