CN202717732U - Selective double-pump sampling equipment - Google Patents
Selective double-pump sampling equipment Download PDFInfo
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- CN202717732U CN202717732U CN 201220247893 CN201220247893U CN202717732U CN 202717732 U CN202717732 U CN 202717732U CN 201220247893 CN201220247893 CN 201220247893 CN 201220247893 U CN201220247893 U CN 201220247893U CN 202717732 U CN202717732 U CN 202717732U
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- pump
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- entrance
- peristaltic pump
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Abstract
The utility model relates to the field of protein purification equipment and particularly discloses selective double-pump sampling equipment. The selective double-pump sampling equipment comprises a peristaltic pump, a plunger pump, a manual two-position three-way reversing valve and a plurality of catheters, wherein the peristaltic pump comprises a peristaltic pump inlet and a peristaltic pump outlet, the plunger pump comprises a plunger pump inlet and a plunger pump outlet, the manual two-position three-way reversing valve comprises a first inlet, a second inlet and a reversing valve outlet, the peristaltic pump outlet is connected with the first inlet through the catheter, and the plunger pump outlet is connected with the second inlet through the catheter. Two pumps are used in the selective double-pump sampling equipment, different sampling paths can be selected according to different chemical properties of samples, an instrument can be perfectly protected, the instrument is more reasonably used, and the service life of the instrument is prolonged.
Description
Technical field
The utility model relates to the protein purification apparatus field, specifically discloses a kind of selectivity double pump sample introduction equipment.
Background technology
Protein purification equipment generally comprises sampling device, corresponding chromatography column and UV detector.Sampling device is used for carrying protein sample to be purified to chromatography column, and in order to tolerate the sample introduction back-pressure of chromatography column, this just requires sampling device to have a motivating force, so sampling device all contains a pump, thereby makes the chromatography column that enters that sample can success.The tradition sampling device only comprises a kind of pump and carries out loading, i.e. ram pump or peristaltic pump.
In carrying out protein purification loading process, take above-mentioned any pump to carry out loading, all there are corresponding shortcoming and advantage.For example, ram pump loading flow velocity homogeneous, and loading pressure is steady, but very faint but its tolerance has the ability of corrosive liquid, thus cause the pump ratio to be easier to damage; Moreover, if liquid such as the urea etc. of ram pump by some easy crystallizations, liquid crystal will impel ram pump to be worn, thereby causes the damage of pump.Although peristaltic pump has well tolerable property to corrosive liquid, its loading flow velocity heterogeneity, and loading pressure transient.Use so single pump to carry out the loading selectivity low, loading can not reach optimization.
The utility model content
In order to overcome the defective of prior art, the utility model discloses a kind of selectivity double pump sample introduction equipment, can select suitable pump to carry out loading according to the difference of sample solution volume property.
The technical solution of the utility model is: a kind of selectivity double pump sample introduction equipment comprises peristaltic pump, ram pump, manual two position three way directional control valve and many conduits; Described peristaltic pump comprises peristaltic pump entrance and peristaltic pump outlet; Described ram pump comprises ram pump entrance and outlet of plunger pump; Described manual two position three way directional control valve comprises the first entrance, the second entrance and reversing valve outlet; Described peristaltic pump outlet is connected with described the first entrance by described conduit, and described outlet of plunger pump is connected with described the second entrance by described conduit.
More excellent, a kind of selectivity double pump sample introduction equipment of the present utility model also comprises housing, described housing is the hollow rectangular parallelepiped, comprises body and cap, described body and described cap clamping; Described body is provided with the first injection port, the second injection port and outlet; Described peristaltic pump, ram pump and manual two position three way directional control valve all are positioned at described enclosure interior; Described the first injection port is connected with described peristaltic pump entrance by conduit; Described the second injection port is connected with described ram pump entrance by conduit; Described outlet is connected with described reversing valve outlet by conduit.
This housing can be protected ram pump, peristaltic pump, manual two position three way directional control valve, inner conduit etc., prevent its breakage, and housing can regular each internal components and pipeline separately, conveniently carrying and the use of whole selectivity double pump sample introduction equipment.Ram pump, peristaltic pump, manual two position three way directional control valve can be positioned over enclosure interior, control unlatching or the conversion of each device by opening housing; Housing also can seal, the switch of ram pump, peristaltic pump is located at described surface of shell to be controlled and opens or close, manually two position three way directional control valve all or part of (hand gear and with reversing valve outlet) is positioned at hull outside, also can realize the technical solution of the utility model.
In the manual two position three way directional control valve described in the utility model, " position " refers to spool several positions, and " leading to " refers to reversing valve several mouths of pipe, perhaps can connect with several pipelines; Therefore the spool of two position three way directional control valve of the present utility model has two positions, and reversing valve comprises two fluid inlets (the first entrance, the second entrance) and a liquid outlet (reversing valve outlet), altogether can connect three pipelines.Control liquid by the position of manual setting spool and enter from one of two fluid inlets, flow to liquid outlet.
The employed conduit of the utility model both can be flexible pipe, also can be the hard tube of solid shape; This conduit is corrosion resistant material, can be the rubber hose that is fit to protein purification in the prior art, emulsion tube, polyethylene tube etc.
Two kinds of sampling pumps (ram pump, peristaltic pump) that selectivity double pump sample introduction equipment of the present utility model contains; Two kinds of sampling pumps are connected with manual two position three way directional control valve respectively by different conduits, are relation in parallel between two sampling pumps, can arbitrarily change; In application, character that can be different according to sample introduction liquid is controlled by regulating manual two position three way directional control valve, selects the sample introduction approach of liquid.
When selectivity double pump sample introduction equipment of the present utility model uses, according to actual demand, select with peristaltic pump passage or ram pump passage.If select to use peristaltic pump, then need the peristaltic pump entrance is connected with protein solution to be purified; The outlet of manual two position three way directional control valve is connected with chromatography column; Control manual two position three way directional control valve, make the passage conducting between interior the first entrance of reversing valve and the reversing valve outlet; Open peristaltic pump, protein solution to be purified flow through successively peristaltic pump, conduit, reversing valve finally flow into the corresponding purifying chromatography column of follow-up connection from the outlet of reversing valve, thereby carry out protein purification.
Two kinds of pumps have been used in a kind of selectivity double pump sample introduction equipment of the present utility model; this design is so that when sample introduction; can different chemical character per sample select different sample introduction approach; so not only can well protect instrument; can also make instrument obtain more reasonably using, prolong the work-ing life of instrument.
Description of drawings
Fig. 1: a kind of selectivity double pump sample introduction device structure schematic diagram (1. peristaltic pump 2. ram pumps 3. manual two position three way directional control valve 4. conduits 11. peristaltic pump entrances 12. peristaltic pumps export the outlet of 21. ram pump entrances, 22. outlet of plunger pumps, 31. first entrances, 32. second entrances, 33. reversing valves)
Fig. 2: a kind of selectivity double pump sample introduction equipment removes to cover plan structure schematic diagram (1. peristaltic pump 2. ram pumps 3. manual two position three way directional control valve 4. conduits 11. peristaltic pump entrances 12. peristaltic pumps export 21. ram pump entrances, 22. outlet of plunger pumps, 31. first entrances, 32. second entrances, 33. reversing valves and export 5. housings, 51. bodies, 52. caps, 511. first injection ports, 512. second injection ports, 513. outlets)
Embodiment
Further set forth the utility model below in conjunction with specific embodiment, should be understood that embodiment only is used for explanation the utility model and is not used in restriction protection domain of the present utility model.
A kind of selectivity double pump sample introduction device structure schematic diagram as shown in Figure 1 comprises peristaltic pump 1, ram pump 2, manual two position three way directional control valve 3 and many conduits 4; Peristaltic pump 1 comprises peristaltic pump entrance 11 and peristaltic pump outlet 12; Ram pump 2 comprises ram pump entrance 21 and outlet of plunger pump 22; Manually two position three way directional control valve 3 comprises the first entrance 31, the second entrance 32 and reversing valve outlet 33; Peristaltic pump outlet 12 is connected with the first entrance 31 by conduit 4, and outlet of plunger pump 22 is connected with the second entrance 32 by conduit 4.
During use, according to actual demand, select with peristaltic pump passage or ram pump passage.If select the ram pump passage, then ram pump entrance 21 is connected with protein solution to be purified, reversing valve outlet 33 is connected with corresponding chromatography column; Control with manual two position three way directional control valve 3, ram pump 2, manual two position three way directional control valve 3 are communicated with by conduit 4, open ram pump 2, protein solution to be purified is pumped into by ram pump 2, flow through conduit and manual two position three way directional control valve 3, thus final being connected with corresponding purifying chromatography column carry out purifying work.
Selectivity double pump sample introduction equipment of the present utility model can also as shown in Figure 2, comprise peristaltic pump 1, ram pump 2, manual two position three way directional control valve 3 and many conduits 4; Peristaltic pump 1 comprises peristaltic pump entrance 11 and peristaltic pump outlet 12; Ram pump 2 comprises ram pump entrance 21 and outlet of plunger pump 22; Manually two position three way directional control valve 3 comprises the first entrance 31, the second entrance 32 and reversing valve outlet 33; Peristaltic pump outlet 12 is connected with the first entrance 31 by conduit 4, and outlet of plunger pump 22 is connected with the second entrance 32 by conduit 4; Selectivity double pump sample introduction equipment also comprises housing 5; Housing 5 is the hollow rectangular parallelepiped, comprises body 51 and cap 52, body 51 and cap 52 clampings; Body 51 is provided with the first injection port 511, the second injection port 512 and outlet 513; Peristaltic pump 1, ram pump 2 and manual two position three way directional control valve 3 all are positioned at housing 5 inside; The first injection port 511 is connected with peristaltic pump entrance 11 by conduit 4; The second injection port 512 is connected with ram pump entrance 21 by conduit 4; Outlet 513 is connected with reversing valve outlet 33 by conduit 4.
Claims (2)
1. a selectivity double pump sample introduction equipment is characterized in that, comprises peristaltic pump, ram pump, manual two position three way directional control valve and many conduits; Described peristaltic pump comprises peristaltic pump entrance and peristaltic pump outlet; Described ram pump comprises ram pump entrance and outlet of plunger pump; Described manual two position three way directional control valve comprises the first entrance, the second entrance and reversing valve outlet; Described peristaltic pump outlet is connected with described the first entrance by described conduit, and described outlet of plunger pump is connected with described the second entrance by described conduit.
2. selectivity double pump sample introduction equipment as claimed in claim 1 is characterized in that, also comprise housing, described housing is the hollow rectangular parallelepiped, comprises body and cap, described body and described cap clamping; Described body is provided with the first injection port, the second injection port and outlet; Described peristaltic pump, ram pump and manual two position three way directional control valve all are positioned at described enclosure interior; Described the first injection port is connected with described peristaltic pump entrance by conduit; Described the second injection port is connected with described ram pump entrance by conduit; Described outlet is connected with described reversing valve outlet by conduit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220247893 CN202717732U (en) | 2012-05-29 | 2012-05-29 | Selective double-pump sampling equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220247893 CN202717732U (en) | 2012-05-29 | 2012-05-29 | Selective double-pump sampling equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202717732U true CN202717732U (en) | 2013-02-06 |
Family
ID=47619561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220247893 Expired - Lifetime CN202717732U (en) | 2012-05-29 | 2012-05-29 | Selective double-pump sampling equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202717732U (en) |
-
2012
- 2012-05-29 CN CN 201220247893 patent/CN202717732U/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130206 |
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| CX01 | Expiry of patent term |