CN202716491U - Novel three-layer co-extrusion film for infusion bag - Google Patents

Novel three-layer co-extrusion film for infusion bag Download PDF

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Publication number
CN202716491U
CN202716491U CN 201220392154 CN201220392154U CN202716491U CN 202716491 U CN202716491 U CN 202716491U CN 201220392154 CN201220392154 CN 201220392154 CN 201220392154 U CN201220392154 U CN 201220392154U CN 202716491 U CN202716491 U CN 202716491U
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China
Prior art keywords
layer
polypropylene
thickness
novel
film
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Expired - Fee Related
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CN 201220392154
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Chinese (zh)
Inventor
王勇祥
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HUNAN XINWUZHOU PHARMACEUTICAL PACKAGING CO Ltd
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HUNAN XINWUZHOU PHARMACEUTICAL PACKAGING CO Ltd
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Priority to CN 201220392154 priority Critical patent/CN202716491U/en
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Abstract

Provided is a novel three-layer co-extrusion film for an infusion bag. The novel three-layer co-extrusion film for the infusion bag is formed by co-extrusion of three structures and 180-200 micrometers in film thickness. The three-layer materials are sequentially polypropylene, ethylene-propylene copolymer and ethylene-propylene-butylene propylene copolymer from outside to inside, the thickness of the polypropylene of the outer layer is 20-50 micrometers, the thickness of the ethylene-propylene copolymer of the middle layer is 70-110 micrometers, and the thickness of the ethylene-propylene-butylene propylene copolymer of the inner layer is 30-50 micrometers. The raw materials from outside to inside is sequentially reduced in melting points, and therefore film heat-seal is simple, convenient and smooth and heat-seal fastness can be guaranteed. The novel three-layer co-extrusion film for the infusion bag has the advantages of being non-poisonous, good in sterilization adaptability and hot-working character and the like, and suitable for venous infusion package of physiological saline solution, glucose and the like.

Description

A kind of novel three-layer co-extruded film for infusion bag
Technical field
The utility model relates to the transfusion packages film, is specially a kind of novel three-layer co-extruded film for infusion bag.
Background technology
Be born in the world the bottled venous transfusion of the first bottle glass from nineteen twenty, so far nearly century.Along with the progress of the science and technology development with society, in order to enlarge and to improve result for the treatment of, improving the intravenous infusion administration security, that the venous transfusion form has successively experienced is open, semi open model, total closed type.Open system is eliminated very soon because the insecurity of its administration is too large; Half-open infusion model is also very common in China, take vial, plastic bottle as representative, has high, the not easy to be recycled defective of production cost; And the closed infusion model bag is take packed in flexible pouchy as main, have advantages of lightweight, volume is little: be beneficial to transportation and deposit.
In general, present closed infusion model bag application clinically mainly contains two kinds of PVC and non-PVC.But because PVC need to add a large amount of plasticizer DEHP, and this composition is very serious to the pollution of medicine, and huge to people's nocuity, native land man has forbidden the production and selling of this series products substantially.Simultaneously, non-PVC packing material is inert material,, good with the compatibility of medicine, the sterilization conformability is good, and its security and the feature of environmental protection have obtained everybody approval, have advantages of that transparency is high: be beneficial to the inspection of visible foreign matters, simultaneously, but direct weighting transfusion is beneficial to transfusion.But, up to the present, the non-PVC multi-layer co-extruded film for transfusion of domestic each infusion solutions pharmaceutical factory use is basic dependence on import still, although domesticly still have several manufacturers producing like product, but its output far can not satisfy domestic demand, the film quality of part manufacturer production is unstable simultaneously, exists difference with imported product.Based on above reason, new source and explained hereafter infusion solutions film need to be arranged, satisfy the Production requirement of most domestic producer.
The utility model content
The technical problem that the utility model solves is to provide a kind of novel three-layer co-extruded film for infusion bag, this novel transfusion bag is nontoxic with film, printing good, high-barrier, weather resisteant is good, pliability is good, heat sealing strength is high simultaneously, to solve the shortcoming in the above-mentioned background technology.
The technical problem that the utility model solves realizes by the following technical solutions:
A kind of novel three-layer co-extruded film for infusion bag, be co-extruded by trilaminate material, and the thickness of the film for infusion bag that is become by the co-extrusion of trilaminate material is 180~200 μ m, wherein, trilaminate material inwardly is followed successively by medical grade polypropylene, second-third binary copolymerization polypropylene and ethylene-propylene-butylene ternary polymerized polypropylene from skin, adopts the machine-shaping of lower blowing water cold type coextrusion process, raw material from outside to inside, its fusing point reduces successively, makes the film heat-sealing easier, smooth, guarantees the heat-sealing fastness.
In the utility model, outer field polypropylene thickness is 25~50 μ m, accounts for 15%~30% of gross thickness, its role is to provide the heat resistance of film bag.
In the utility model, the second in intermediate layer-third binary copolymerization polypropylene thickness is 70~110 μ m, accounts for 40%~60% of gross thickness, and it is film major function layer, and simultaneously, the binary copolymerization polypropylene is soft, has guaranteed the softness of Infusion Bags.
In the utility model, internal layer is hot sealing layer, its composition ethylene-propylene-butylene ternary polymerized polypropylene, and thickness is 30~50 μ m, accounts for 20%~30% of gross thickness, has fabulous stability and heat sealability, guarantees stability and the sealing property of splendid attire liquid.
In the utility model, three-layer co-extruded transfusion bag with the demand barrier property of film is: steam penetrating capacity<5.0g/(m 224h), oxygen transit dose<1200cm 3/ (m 224h0.1MPa), nitrogen transit dose<600cm 3/ (m 224h0.1MPa).This just requires film will reach certain thickness could satisfy standard-required, substantially can satisfy above-mentioned requirements when polypropylene thickness reaches 180 μ m when above.
Compared with prior art, advantage of the present utility model has:
1, the ethylene-propylene of internal layer employing-butylene ternary polymerized polypropylene, have good biological and chemical inertia, widely drug compatibility and heat endurance and good heat sealability;
2, adopt main material mostly to be polypropylene or modified polypropene, transparency is high, can not whiten in sterilization and use procedure, and sterilization adaptability is good;
3, barrier property is good, guarantees the long-term effectiveness of medicine;
4, have higher heat seal strength, the Infusion Bags anti-dropping capability of making is good, easy leakage do not occur;
5, between thin layer, combination firmly, is difficult for peeling off;
6, in production process to the film external corona of rolling, guarantee the printing performance of film.
Description of drawings
Fig. 1 is the schematic diagram of the utility model preferred embodiment.
The specific embodiment
For technological means, creation characteristic that the utility model is realized, reach purpose and effect is easy to understand, below in conjunction with concrete diagram, further set forth the utility model.
Referring to the schematic diagram of the preferred embodiment of a kind of novel three-layer co-extruded film for infusion bag of Fig. 1, in the present embodiment, be followed successively by from top to bottom outer 1, middle level 2, internal layer 3.The raw material of selecting are respectively as medical grade polypropylene, second-third binary copolymerization polypropylene and ethylene-propylene-butylene ternary polymerized polypropylene, have lower heat-sealing temperature.
Adopt the processing mode of downward-blowing water-cooling, cooling water is medicinal purified water, and cooling water recycles through high-efficient water purification installation, and makes regular check on its sanitation performance; Blown film is used to such an extent that cold wind is 100 grades of pure airs that filter through multi-stage, efficient, and rolling in 10000 grades of cleaning shops is cut.
In the present embodiment, electron irradiation and sided corona treatment need be do not passed through, transfusion package and printing can be directly used in.Each is rolled up multi-layer co-extruded concrete performance and sees the following form:
? Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5
Outer 20% 25% 30% 25% 20%
The middle level 50% 45% 40% 55% 60%
Internal layer 30% 30% 30% 20% 20%
To the film portion performance test, correlated performance is as follows according to national standard YBB00102005:
? Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5
Sterilization adaptability Transparent Transparent Transparent Transparent Transparent
Splitting Well Well Generally Well Well
Heat sealing strength 33.5N/15mm 32.7N/15mm 34.6N/15mm 28.6N/15mm 27.8N/15mm
Barrier property Meet Meet Meet Meet Meet
Hot strength >28 MPa >28 MPa >28 MPa >28 MPa >28 MPa
Light transmittance 82% 83% 82% 84% 85%
The leachable experiment Meet Meet Meet Meet Meet
Microbial limit Meet Meet Meet Meet Meet
Undue toxicity * Meet Meet Meet Meet Meet
Above demonstration and described basic principle of the present utility model, principal character and advantage of the present utility model.The technical staff of the industry should understand; the utility model is not restricted to the described embodiments; that describes in above-described embodiment and specification just illustrates principle of the present utility model; under the prerequisite that does not break away from the utility model spirit and scope; the utility model also has various changes and modifications, and these changes and improvements all fall in claimed the utility model scope.The claimed scope of the utility model is defined by appending claims and equivalent thereof.

Claims (2)

1. novel three-layer co-extruded film for infusion bag, be co-extruded by trilaminate material, it is characterized in that, thickness is 180~200 μ m, simultaneously, trilaminate material inwardly is followed successively by polypropylene, second-third binary copolymerization polypropylene and ethylene-propylene-butylene ternary polymerized polypropylene from skin, adopt the machine-shaping of lower blowing water cold type coextrusion process, and the described outer field polypropylene thickness second-third binary copolymerization polypropylene thickness that is 25~50 μ m, intermediate layer be 70~110 μ m, internal layer ethylene-propylene-butylene ternary polymerized polypropylene thickness is 30~50 μ m.
2. a kind of novel three-layer co-extruded film for infusion bag according to claim 1, is characterized in that, the described outer polypropylene that adopts is medical grade polypropylene.
CN 201220392154 2012-08-09 2012-08-09 Novel three-layer co-extrusion film for infusion bag Expired - Fee Related CN202716491U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201220392154 CN202716491U (en) 2012-08-09 2012-08-09 Novel three-layer co-extrusion film for infusion bag

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201220392154 CN202716491U (en) 2012-08-09 2012-08-09 Novel three-layer co-extrusion film for infusion bag

Publications (1)

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CN202716491U true CN202716491U (en) 2013-02-06

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114851672A (en) * 2022-07-07 2022-08-05 山东兰德英科新材料科技有限公司 Method for preparing infusion bag by adopting biodegradable infusion bag special material

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114851672A (en) * 2022-07-07 2022-08-05 山东兰德英科新材料科技有限公司 Method for preparing infusion bag by adopting biodegradable infusion bag special material
CN114851672B (en) * 2022-07-07 2022-09-02 山东兰德英科新材料科技有限公司 Method for preparing infusion bag by adopting biodegradable infusion bag special material

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C14 Grant of patent or utility model
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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130206

Termination date: 20140809

EXPY Termination of patent right or utility model