CN202705352U - Single-pore micro biochip - Google Patents

Single-pore micro biochip Download PDF

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Publication number
CN202705352U
CN202705352U CN 201220371255 CN201220371255U CN202705352U CN 202705352 U CN202705352 U CN 202705352U CN 201220371255 CN201220371255 CN 201220371255 CN 201220371255 U CN201220371255 U CN 201220371255U CN 202705352 U CN202705352 U CN 202705352U
Authority
CN
China
Prior art keywords
micro
biochip
pore
micropore
single hole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN 201220371255
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Chinese (zh)
Inventor
张�浩
杨欣
邱一帆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NANJING POTOMAC BIO-TECHNOLOGY Co Ltd
Original Assignee
NANJING POTOMAC BIO-TECHNOLOGY Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NANJING POTOMAC BIO-TECHNOLOGY Co Ltd filed Critical NANJING POTOMAC BIO-TECHNOLOGY Co Ltd
Priority to CN 201220371255 priority Critical patent/CN202705352U/en
Application granted granted Critical
Publication of CN202705352U publication Critical patent/CN202705352U/en
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Expired - Fee Related legal-status Critical Current

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Abstract

The utility model relates to a single-pore micro biochip. A hollow part is formed between an upper cover and a bottom and filled with a chip membrane and a water absorbing material; the upper cover is provided with micro pores; an air hole is formed below each micro pore; a boss frame is arranged on the circumference of each micro pore; a rib plate frame is arranged on the circumference of each micro pore on the back of the upper cover; and a bayonet and a clamping table are arranged on each of four walls of each single-pore micro chip. The single-pore micro biochip overcomes the defects that the biochip in the prior art is high in manufacturing cost, can be operated by only one person every time, is long in reaction time, low in efficiency and high in consumption of detection reagents and samples to be detected, is not suitable for simultaneously detecting a large batch of samples at one time and the like. The single-pore micro biochip integrates the advantages of operation flexibility of a single-pore biochip and low consumption of detection reagents and samples, low cost, short reaction time and high efficiency of a multi-pore micro biochip; and the application range of the chip is enlarged.

Description

The single hole micro-biochip
Technical field
The utility model relates to a kind of biochip, particularly a kind of single hole micro-biochip.
Background technology
Before the present utility model, existing biochip is mainly single hole chip and porous micro-biochip.The single hole chip is made of loam cake and going to the bottom, and the centre is filled with related chip film and water-absorbing material, on cover and offer funnel shaped hole, general size is 1 square centimeter, offers corresponding infiltration, breather hole below the hole, as shown in Figure 1.This chip manufacturing cost is high, can only carry out single part of operation at every turn, long reaction time, and efficient is low, and detection reagent and sample to be tested consumption are large, are not suitable for the disposable sample in enormous quantities that detects simultaneously, such as blood station examination, crowd's health check-up, inspection and quarantine etc.Porous micro-biochip is characterised in that to cover and is provided with a plurality of micropores, and the periphery of each micropore arranges the boss frame, at the periphery of each micropore of the loam cake back side floor frame is set, as shown in Figure 3.This chip can cause unnecessary waste when detecting the sample of short run.
Summary of the invention
The purpose of this utility model is to overcome defects, designs a kind of single hole micro-biochip.
The technical solution of the utility model:
The single hole micro-biochip, hollow space at loam cake, between going to the bottom, be filled with chip film, water-absorbing material, on cover and be provided with micropore, the micropore below is provided with breather hole, its technical characteristics is that the micropore periphery arranges the boss frame, at the periphery of each micropore of the loam cake back side floor frame is set, and each single hole microchip wall arranges bayonet socket and Ka Tai.
Advantage of the present utility model has had both single hole biochip flexible operation and porous micro-biochip detection reagent and the sample consumption is few, cost is low, the reaction times is short, efficient is high advantage, has further enlarged the range of application of chip.
Description of drawings
Fig. 1---existing single hole biochip structural representation.
Fig. 2---porous micro-biochip structural principle synoptic diagram.
The porous micro-biochip synoptic diagram of Fig. 3---48 micropores.
Fig. 4---the utility model perspective view.
The biochip synoptic diagram of Fig. 5---12 micropores being combined into by the single hole micro-biochip.
Each label represents that corresponding component names is as follows among Fig. 2:
Micropore 1, boss frame 2, small boss 3, floor frame 4, breather hole 5, hollow space 6, bayonet socket 7, loam cake 8, go to the bottom 9, card platform 10, draw-in groove 11, lesser calorie platform 12.
Embodiment
As shown in Figure 2:
Offer micropore 1 on the loam cake 8, up big and down small, be ladder structure, i.e. doline, top specification 4 * 4mm; In order to prevent the impact of stretching of liquid between each micropore 1, at the periphery of each micropore 1 boss frame 2 is set, boss frame 2 is square, high 2mm, thick 0.5mm; For guaranteeing the relatively independent interference that is not subjected to other micropores 1 of its reaction compartment, in micropore 1 position at loam cake 8 back sides floor frame 4 is set; Columniform small boss 3 is set, each micropore 1 corresponding 2 small boss 3, minute left and right two settings (omit among the figure, only drawn), diameter 1mm, high 4.5mm in each micropore 1 corresponding position of going to the bottom on 9 with top; With top each micropore 1 corresponding position (infiltration) breather hole 5 is set in 9 cross sections of going to the bottom, each micropore 1 arranges 2 breather holes 5 (omit among the figure, only drawn), and breather hole 5 plays infiltration and breathes freely diameter 1mm; Below each micropore 1 and for loam cake 8 back side hollow spaces 6, i.e. the chip film of floor frame 4 interior space-filling dimensions, water-absorbing material etc.; A card platform 10 is set on loam cake 8 inboards, and 9 upper outside of going to the bottom arrange bayonet socket 7, and bayonet socket 7 is stuck on the card platform 10, and loam cake 89 is fixedly connected with going to the bottom; Hollow space be by loam cake 8, go to the bottom 9 and left and right floor frame 4 consist of.
As shown in Figure 3:
It is the biochip of 48 micropores.The single hole micro-biochip arranges supporting draw-in groove 11 and lesser calorie platform 12 at wall on the basis of porous micro-biochip structure, specification for long * wide * dark: 2 * 1 * 1mm, its structure as shown in Figure 4.
The explanation of the utility model application process:
During use, can be according to number of awaiting test sample, the single hole micro-biochip of respective numbers is connected with Ka Tai by draw-in groove, as shown in Figure 5, be the biochip of 12 micropores being combined into by the single hole micro-biochip, can 12 samples of disposable detection.

Claims (5)

1. single hole micro-biochip, hollow space at loam cake, between going to the bottom, be filled with chip film, water-absorbing material, on cover and be provided with micropore, the micropore below is provided with breather hole, it is characterized in that the micropore periphery arranges the boss frame, at the periphery of each micropore of the loam cake back side floor frame is set, each single hole microchip wall arranges bayonet socket and Ka Tai.
2. single hole micro-biochip according to claim 1 is characterized in that breather hole is arranged in the cross section of going to the bottom, and arranges small boss going to the bottom of breather hole periphery.
3. single hole micro-biochip according to claim 1 is characterized in that bayonet socket on the loam cake inboard, and bayonet socket is in the upper outside of going to the bottom.
4. single hole micro-biochip according to claim 1 is characterized in that the doline that micropore is big up and small down.
5. single hole micro-biochip according to claim 1 is characterized in that hollow space is by loam cake, goes to the bottom and left and right floor frame consists of.
CN 201220371255 2012-07-26 2012-07-26 Single-pore micro biochip Expired - Fee Related CN202705352U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201220371255 CN202705352U (en) 2012-07-26 2012-07-26 Single-pore micro biochip

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201220371255 CN202705352U (en) 2012-07-26 2012-07-26 Single-pore micro biochip

Publications (1)

Publication Number Publication Date
CN202705352U true CN202705352U (en) 2013-01-30

Family

ID=47585673

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 201220371255 Expired - Fee Related CN202705352U (en) 2012-07-26 2012-07-26 Single-pore micro biochip

Country Status (1)

Country Link
CN (1) CN202705352U (en)

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Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130130

Termination date: 20210726