CN202694659U - Tumor blood channel diffusion demonstration model - Google Patents
Tumor blood channel diffusion demonstration model Download PDFInfo
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- CN202694659U CN202694659U CN 201220297817 CN201220297817U CN202694659U CN 202694659 U CN202694659 U CN 202694659U CN 201220297817 CN201220297817 CN 201220297817 CN 201220297817 U CN201220297817 U CN 201220297817U CN 202694659 U CN202694659 U CN 202694659U
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- basement membrane
- extracellular matrix
- blood vessel
- blood
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Abstract
The utility model relates to a teaching aid for medical teaching. A tumor blood channel diffusion demonstration model can vividly demonstrate the tumor blood channel diffusion process for the students. According to the technical scheme, the model comprises a base and a demonstration plate; the demonstration plate is provided with a primary cancer model, a basement membrane model, an extracellular matrix model, a blood vessel model and a tissue space model; the basement membrane model is arranged below the primary cancer; the extracellular matrix model is arranged below the basement membrane model; the blood vessel model is located between the extracellular matrix and the tissue space model; the extracellular matrix is provided with an extracellular matrix channel; and an opening is arranged in the basement membrane. A regulation switch is arranged at the lower end of each of the primary cancer and the blood vessel basement membrane. The tumor blood channel diffusion demonstration model provided by the utility model is vivid and easy to operate and can help the medical students to completely understand the occurrence and development process of the tumor blood channel diffusion.
Description
Technical field
The utility model relates to a kind of medical teaching teaching aid, particularly tumour blood road diffusion demonstrating model.
Background technology
In Teaching of Pathology, malignant tumour be the most important reason that malignant tumour is difficult to effect a radical cure and cause death, and the process of Blood route metastasis is complicated, its links of student's indigestion by local infiltration and the diffusion of blood road.Teaching material only provides static signal figure, and the multimedia animation does not have the visual stimulus effect of ocular demonstration in kind, and the teacher says that time service also is difficult to the demonstration that true process is complete out with simple language description or plate figure, is difficult to attract student's notice.
Summary of the invention
The utility model content:
The utility model shows that to the malignant tumour Blood route metastasis existence is not directly perceived for prior art, not vivid, its pathologic process of student's indigestion and provide a kind of simple in structure, the simulation tumour Blood route metastasis demonstrating model of visual pattern, for achieving the above object, the utility model adopts following technical scheme: simulation tumour Blood route metastasis demonstrating model, comprise base and demonstration board, be provided with the primary tumor model on the demonstration board, the basilar memebrane model, the extracellular matrix model, the basement membrane of blood vessel model, vascular pattern and tissue space model, it is characterized in that: described primary tumor below is set to the basilar memebrane model, extracellular matrix model top is the basilar memebrane model, the below is the basement membrane of blood vessel model, vascular pattern is provided with the extracellular matrix passage in the described extracellular matrix model between basement membrane of blood vessel model and tissue space model.Described basilar memebrane and basement membrane of blood vessel are provided with opening, and primary carcinoma model, basement membrane of blood vessel model are connected the lower end with the blood vessel slit and are provided with by-pass cock.
According to technique scheme, pathologic process-tumour cell that the utility model can demonstrate the tumour Blood route metastasis intuitively form-passes blood vessel-metastatic tumor and forms from primary tumor basilar memebrane-pass extracellular matrix-the penetrate blood vessel-knurl bolt that falls-break through.Can bring following beneficial effect:
(1) breaks through focal points, the difficult point of tumour Blood route metastasis, improved teaching efficiency;
(2) rational in infrastructure, simple to operate, make things convenient for the student in person to operate;
(3) by the carcinogenesis of human of demonstration energy complete understanding tumour blood road diffusion, make the student to the biological property of malignant cell darker understanding arranged.
Description of drawings:
Accompanying drawing 1 is the utility model structural representation.
Among the figure:
1, primary tumor model
2, primary tumor cell model
3, primary tumor cell separation
4, primary tumor by-pass cock
5, basilar memebrane model
6, basilar memebrane opening
7, extracellular matrix model
8, extracellular matrix passage
9, basement membrane of blood vessel opening
10, basement membrane of blood vessel model
11, vascular pattern
12, basement membrane of blood vessel by-pass cock
13, lumen of vessels
14, tumor cell embolus
15, vascular wall slit
16, vascular wall slit by-pass cock
17, tissue space model
18, metastatic tumor
19, base
20, demonstration board.
Embodiment:
In order to make the utility model realize technological means, creation characteristic, to reach purpose and effect is easy to understand, below in conjunction with concrete demonstration, further set forth the utility model.
Invasion and attack and transfer are the topmost biological markers of malignant tumour, can be divided into local infiltration and the blood road is sent out.Malignant cell can be divided into following a few step for the invasion and attack of extracellular matrix: (1) tumour cell is separated from one another; (2) stick together with basilar memebrane; (3) extracellular matrix degradation; (4) migration of tumour cell.
The blood road is sent out and is divided into: (1) passes basement membrane of blood vessel; (2) penetrate blood vessel; (3) the knurl bolt forms; (4) pass blood vessel; (5) form metastatic tumor.
Based on above-mentioned principle, the utility model provides demonstrating model as shown in the figure:
Simulation metastases demonstrating model described in the utility model, comprise base 19 and demonstration board 20, be provided with primary carcinoma model 1 on the demonstration board 20, basilar memebrane model 5, extracellular matrix model 7, basement membrane of blood vessel model 10, vascular pattern 11 and tissue space model 17, described primary carcinoma model 1 below is set to basilar memebrane model 5, basilar memebrane model 5 belows are set to extracellular matrix model 7, extracellular matrix model 7 belows are basement membrane of blood vessel model 10, vascular pattern 11 is between basement membrane of blood vessel model 10 and tissue space model 17, described extracellular matrix model 7 is provided with extracellular matrix passage 8, is provided with opening 6 on the basilar memebrane model, 9.Described primary tumor model 1, basement membrane of blood vessel model 10 and blood vessel slit are connected 15 lower ends and are respectively arranged with by- pass cock 4,12,16.
Being provided with two layers of substrate membrane modle (basilar memebrane model 5 and basement membrane of blood vessel model 10) between primary tumor model and the vascular pattern, is extracellular matrix model 7 between the two layers of substrate film, with the normal structure structure of emulation tumor cell migration process.Extracellular matrix passage 8 and by- pass cock 4,12,16 are set, can regulate the speed of tumor cell migration, clearer observation transition process.The utility model combines displaying with tumour cell local infiltration and Blood route metastasis, makes the student to the whole process of tumour Blood route metastasis darker understanding be arranged.
The concrete presentation process of exemplary model according to technique scheme is as follows:
Primary tumor oncocyte 2 adhesions descend and separate 3 and move down by soaking and attack substrate mould model 6 and move into extracellular matrix passages 8, can regulate primary tumor model by-pass cock 4 this moment with the descending speed of control oncocyte migration.Oncocyte penetrates in the lumen of vessels 13 of vascular pattern 11 by passing basement membrane of blood vessel opening 9, form tumor cell embolus 14, because Action of Gravity Field is lower mobile forward along vascular pattern 11, passes at last blood vessel slit 15, invades tissue space model 17 and formation metastatic tumor 18.
Finished the pathologic process of tumour Blood route metastasis by above simulation.
Claims (2)
1. tumour blood road spreads demonstrating model, comprise base and demonstration board, be provided with primary tumor model, basilar memebrane model, extracellular matrix model, basement membrane of blood vessel model, vascular pattern and tissue space model on the demonstration board, it is characterized in that: described primary tumor below is set to the basilar memebrane model, extracellular matrix model top is the basilar memebrane model, the below is the basement membrane of blood vessel model, vascular pattern is provided with the extracellular matrix passage in the described extracellular matrix model between basement membrane of blood vessel model and tissue space model.
2. tumour blood according to claim 1 road diffusion demonstrating model, it is characterized in that: described basilar memebrane and basement membrane of blood vessel are provided with opening, and primary carcinoma model, basement membrane of blood vessel model are connected the lower end with the blood vessel slit and are provided with by-pass cock.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220297817 CN202694659U (en) | 2012-06-25 | 2012-06-25 | Tumor blood channel diffusion demonstration model |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220297817 CN202694659U (en) | 2012-06-25 | 2012-06-25 | Tumor blood channel diffusion demonstration model |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202694659U true CN202694659U (en) | 2013-01-23 |
Family
ID=47550242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220297817 Expired - Fee Related CN202694659U (en) | 2012-06-25 | 2012-06-25 | Tumor blood channel diffusion demonstration model |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202694659U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102723039A (en) * | 2012-06-25 | 2012-10-10 | 关真民 | Model for demonstrating tumor vascular dissemination |
-
2012
- 2012-06-25 CN CN 201220297817 patent/CN202694659U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102723039A (en) * | 2012-06-25 | 2012-10-10 | 关真民 | Model for demonstrating tumor vascular dissemination |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130123 Termination date: 20130625 |