CN202589946U - Pre-charging type preparation of heparin type injection - Google Patents
Pre-charging type preparation of heparin type injection Download PDFInfo
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- CN202589946U CN202589946U CN 201120522008 CN201120522008U CN202589946U CN 202589946 U CN202589946 U CN 202589946U CN 201120522008 CN201120522008 CN 201120522008 CN 201120522008 U CN201120522008 U CN 201120522008U CN 202589946 U CN202589946 U CN 202589946U
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- needle
- heparin
- precharging
- preparation
- syringe
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Abstract
The utility model discloses a pre-charging type preparation of heparin type injections, which comprises a pre-charging type injector. The pre-charging type injector comprises a needle pipe, a push rod, a needle tip and a protecting cap. One end of the needle pipe is provided with a needle tip seat. The needle tip is fixed on the center of the needle tip seat. The protecting cap is sleeved outside the needle tip and the needle tip seat. One end of the push rod is provided with a piston cooperating with the needle pipe in a sliding way. The piston, the needle tip seat and the needle pipe form a liquid medicine chamber through in an enclosing way. Heparin type liquid medicines are contained in the liquid medicine chamber. The preparation provided in the utility model is very convenient for medical uses and requires no suction and no installation of needle tips. The injection cost of a patient is lowered. The residue is reduced. Secondary pollution possibilities are slimmed. Medicine-consuming safety of patients is enhanced.
Description
Technical field
This utility model relates to a kind of pharmaceutical preparation, especially the precharging preparation of heparin class injection.
Background technology
The heparin series products has injection and two kinds of dosage forms of freeze-dried powder on the present domestic medical market, all uses the cillin bottle packing, in use, need unpack earlier, and then use syringe pump, is easy to cause secondary pollution like this.It is residual that the dead space of the syringe needle of syringe and needle tubing junction is prone to produce medicinal liquid, and use amount is inaccurate.Common in addition syringe needle subcutaneous injection area is big, and patient's pain is increased.Equally, the powder pin need add liquid redissolution back to be used, and also can produce same problem.
Precharging preparation is with the inner packing of precharging type syringe as product, it be with the direct fill of injectable drug in pre-filled needle tubing, and injection needle is installed on the needle tubing, syringe and medicinal liquid packing container are united two into one, direct injection during use, very convenient.Precharging type syringe is compared with traditional packaging material (cillin bottle or ampoule packing) as a kind of interior packaging material of direct contact medicine, and is safer convenient.At home, pre-filled packing has been applied in fields such as erythropoietin, interferon, human growth hormone, antitumor drug, but the application in the pharmaceutical preparation of heparin class does not but also occur.
The utility model content
The purpose of this utility model is to overcome defective of the prior art, and a kind of precharging preparation of heparin class injection is provided, and can overcome heparin class pharmaceutical preparation deficiency in use in the past, is suitable for packing the injection with small volume of heparin class.
The following technical proposals that adopted this utility model solves above-mentioned technical problem:
A kind of precharging preparation of heparin class injection comprises precharging type syringe, wherein; Said precharging type syringe comprises needle tubing, push rod, syringe needle and helmet, and an end of said needle tubing is provided with needle holder, and the center fixation of needle holder has said syringe needle; Said helmet is socketed on outside said syringe needle and the needle holder; One end of said push rod is provided with the piston that is slidingly matched with needle tubing, and said piston, needle holder and said needle tubing surround a medicinal liquid cavity, and heparin class medicinal liquid is housed in the said medicinal liquid cavity.
Preferable, be provided with the elastic packing plug in the said helmet.
Preferable, establish the groove that is complementary with wire tip profile in the said elastic packing plug.
Said syringe needle is a stainless steel, and diameter is at 0.2-0.5mm, and the needle point of syringe needle uses the most carefully, the most sharp-pointed double inclined plane, three inclined-planes or five inclined-planes, and the patient has only slight sensation during injection.
Needle tubing is medicinal Pyrex material, and piston is the butyl rubber material, this material choose the absorption that can reduce medicinal liquid.
Above-mentioned needle tubing volume is 0.2ml, 0.3ml, 0.4ml, 0.5ml, 0.6ml, 0.8ml, 1ml, 1.2ml, 1.5ml, 2ml, 2.5ml, 3ml or 5ml, according to the medical treatment and the market demand, can also increase new specification.Because the clinical recommendation use amount of various medicinal liquids is different, also because the difference of use amount due to patient's the individual variation itself, the specification of the precharging preparation of the heparin class medicine of this utility model can be diversified.
Preferable, above-mentioned syringe needle helmet outer surface is provided with anti-skidding stricture of vagina.
In the making of precharging type syringe, through sterilization treatment, after the detection, can directly be used for the fill of heparin class medicine, program is simple, and is easy to use.The fill of precharging preparation, lamp inspection, decals, stubborn bar, plastic packaging all adopt automatic assembly line to accomplish.
Above-mentioned heparin class medicinal liquid is a heparin class medicinal liquid, comprises the injection of medicines such as heparin sodium, low molecular weight heparin sodium, low molecular weight calcium heparin, Enoxaparin Sodium, Enoxaparin calcium.
Preferable, above-mentioned needle tubing is provided with scale.
The advantage that precharging preparation is used for the pharmaceutical preparation of heparin class mainly contains:
1, medical care is extremely easy to use, need not suction, need not to install syringe needle, reduces patient's injection cost;
2, avoid the use of and aspirate repeatedly behind the diluent and cause the generation of plug bits, reduces residual and the secondary pollution chance;
3, no dead space design can be fully utilized, the noresidue medicinal liquid, and dosage is more accurate;
4, the UD volume is little, and the distending pain sense is lighter during injection;
5, syringe needle is sharp keen, and handled easily reduces sensation of pricking;
6, disposable use, direct injection reduces pollution risk, increases patient's drug safety.
Because above advantage has determined the precharging preparation of heparin class medicine will have higher using value and better prospect, the precharging preparation of therefore inventing heparin class medicine is necessary.
Description of drawings
Fig. 1: the precharging preparation sketch map of heparin class injection
The specific embodiment
The precharging preparation of heparin class injection as shown in Figure 1 comprises precharging type syringe, wherein; Said precharging type syringe comprises needle tubing 1, push rod 2, syringe needle 3 and helmet 4, and an end of needle tubing 1 is provided with needle holder 5, and the center fixation of needle holder has syringe needle 3; Helmet 4 is socketed on outside syringe needle 3 and the needle holder 5; One end of push rod 2 is provided with the piston 6 that is slidingly matched with needle tubing, and piston 6, needle holder 5 and 4 needle tubings 1 surround a medicinal liquid cavity 7, and heparin class medicinal liquid is housed in the medicinal liquid cavity.
Further, be provided with elastic packing plug 8 in the helmet 4.
Further, establish the groove that is complementary with wire tip profile in the elastic packing plug 8.
Above-mentioned syringe needle 3 is a stainless steel, and diameter is 0.2-0.5mm, and the needle point of syringe needle is a double inclined plane.Needle tubing 1 is medicinal Pyrex material, and piston 6 is the butyl rubber material.
With precharging type syringe process sterilization treatment, after the detection, under the local laminar flow condition, in the cavity that fill heparin sodium injection, low molecular weight heparin sodium injection, low molecular weight calcium heparin injection, enoxaparin sodium injection, Enoxaparin calcium injection to needle tubing, conehead and piston surround respectively in the different precharging type syringes; Every kind of medicinal liquid difference fill 2000AxaIU, 2500AxaIU, 4000AxaIU, 5000AxaIU; 6000AxaIU, 8000AxaIU, 10000AxaIU, 12000AxaIU; 15000AxaIU, 20000AxaIU, 25000AxaIU; 30000AxaIU, 50000AxaIU encapsulates with aluminium foil or bubble-cap formula after fill is accomplished.The fill of precharging preparation, lamp inspection, decals, stubborn bar, plastic packaging all adopt automatic assembly line to accomplish.
Through stability test, the medicinal liquid in the precharging preparation of heparin class injection is compared with the identical medicinal liquid of fill in cillin bottle or ampoule bottle, and its stability quite.
Claims (8)
1. the precharging preparation of a heparin class injection is characterized in that, comprises precharging type syringe; Said precharging type syringe comprises needle tubing, push rod, syringe needle and helmet, and an end of said needle tubing is provided with needle holder, and the center fixation of needle holder has said syringe needle; Said helmet is socketed on outside said syringe needle and the needle holder; One end of said push rod is provided with the piston that is slidingly matched with needle tubing, and said piston, needle holder and said needle tubing surround a medicinal liquid cavity, and heparin class medicinal liquid is housed in the said medicinal liquid cavity.
2. the precharging preparation of heparin class injection according to claim 1 is characterized in that, is provided with the elastic packing plug in the said helmet.
3. like the precharging preparation of the said heparin class of claim 2 injection, it is characterized in that, establish the groove that is complementary with wire tip profile in the said elastic packing plug.
4. the precharging preparation of heparin class injection according to claim 1 is characterized in that said syringe needle diameter is at 0.2-0.5mm, and the needle point of syringe needle is double inclined plane, three inclined-planes or five inclined-planes.
5. the precharging preparation of heparin class injection according to claim 1 is characterized in that said needle tubing volume is 0.2ml, 0.3ml, 0.4ml, 0.5ml, 0.6ml, 0.8ml, 1ml, 1.2ml, 1.5ml, 2ml, 2.5ml, 3ml or 5ml.
6. the precharging preparation of heparin class injection according to claim 1 is characterized in that said syringe needle helmet outer surface is provided with anti-skidding stricture of vagina.
7. the precharging preparation of heparin class injection according to claim 1 is characterized in that said needle tubing is provided with scale.
8. like the precharging preparation of the said heparin class of arbitrary claim injection among the claim 1-7, it is characterized in that said heparin class medicinal liquid is selected from heparin sodium, low molecular weight heparin sodium, low molecular weight calcium heparin, Enoxaparin Sodium and Enoxaparin calcium.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120522008 CN202589946U (en) | 2011-12-14 | 2011-12-14 | Pre-charging type preparation of heparin type injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120522008 CN202589946U (en) | 2011-12-14 | 2011-12-14 | Pre-charging type preparation of heparin type injection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202589946U true CN202589946U (en) | 2012-12-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201120522008 Expired - Lifetime CN202589946U (en) | 2011-12-14 | 2011-12-14 | Pre-charging type preparation of heparin type injection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202589946U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104548278A (en) * | 2014-12-31 | 2015-04-29 | 辰欣药业股份有限公司 | Enoxaparin sodium tube sealing injection and preparation method thereof |
| CN107773813A (en) * | 2016-08-31 | 2018-03-09 | 上海凯茂生物医药有限公司 | A kind of precharging preparation of the erythropoietin class parenteral solution with safety guard |
-
2011
- 2011-12-14 CN CN 201120522008 patent/CN202589946U/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104548278A (en) * | 2014-12-31 | 2015-04-29 | 辰欣药业股份有限公司 | Enoxaparin sodium tube sealing injection and preparation method thereof |
| CN107773813A (en) * | 2016-08-31 | 2018-03-09 | 上海凯茂生物医药有限公司 | A kind of precharging preparation of the erythropoietin class parenteral solution with safety guard |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20121212 |
|
| CX01 | Expiry of patent term |