CN201612837U - Pre-filling injection agent of prostaglandin and derivatives thereof - Google Patents
Pre-filling injection agent of prostaglandin and derivatives thereof Download PDFInfo
- Publication number
- CN201612837U CN201612837U CN2009201097013U CN200920109701U CN201612837U CN 201612837 U CN201612837 U CN 201612837U CN 2009201097013 U CN2009201097013 U CN 2009201097013U CN 200920109701 U CN200920109701 U CN 200920109701U CN 201612837 U CN201612837 U CN 201612837U
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- overcoat
- prostaglandin
- piston
- push rod
- helmet
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Abstract
The utility model discloses a pre-filling injection agent, and relates to the field of pharmaceutical preparations. A pre-potting injector is adopted as a container for the prostaglandin and the derivative injection agent thereof. A needle-free pre-potting injector adopts the structure that an opening is formed at the rear end of an outer sleeve 1, and a rubber sleeve 5 for sealing a port is mounted on a front end conical head; and a piston 2 is connected with a push rod 3. A need type pre-potting injector adopts the structure that an opening is formed at the rear end of the outer sleeve 1, a protective cap 5 is sleeved on the front end conical head, a needle head 4 is coaxially mounted on the protective cap 5, and the piston 2 is connected with the push rod 3. The volume of the outer sleeve 1 ranges from 1 ml to 5 ml. The prostaglandin and the derivatives thereof include injections such as the prostaglandin, carboprost tromethamine, beraprost sodium, iloprost, latanoprost, bimatoprost, travoprost, dinoprost, misoprostol and the like. The utility model reduces drug residue, is accurate in dosage, and avoids the risk of recontamination to medicine wrapped by a common ampoule or a vial during the suction process, thereby enhancing the safety of a patient.
Description
Technical field
This utility model relates to a kind of pre-filled injection, the especially prostaglandin of medicine and the pre-filled injection of derivant thereof.
Background technology
Pre-filled injection is with the container of the pre-encapsulated injector after the sterilization as injection, replaces traditional ampoule and cillin bottle, is a kind of novel high-grade pharmaceutical pack container.Medicinal liquid directly packed into preserve in the syringe, this product is divided into band pin type and is not with two kinds on pin type, all local laminar flow production in ten thousand grades of cleaning shops.The be directly used in injection of band pin type is not installed sterilized syringe needle before use with the need of pin type.
Simple and convenient when pre-filled injection uses, and syringe itself has good sealing, and medicinal liquid can long preservation.Because the convenience of its fill and use has very high safety again, avoid the secondary pollution that may bring in the use, in some medicines (as: biological product) injection, replace traditional ampoule and cillin bottle just fast.
The prior art the most close with this utility model is that name is called the Chinese invention patent application of " the recombinant human interferon alpha 2 b injection of prefilled injector package ", publication number CN 1748788A; And name is called the Chinese utility model patent of " a kind of precharging preparation of antibiotic medicine ", Granted publication CN2905051Y; And name is called the Chinese utility model patent of " a kind of precharging preparation of antitumor drug ", Granted publication CN2917637Y.Precharging preparation is used for the packing of biological preparation mostly at home, but the application in prostaglandin and derivant injection thereof is not also arranged.
The injection of prostaglandin and derivant thereof is cillin bottle or ampoule packing on the domestic market at present, in use, need unpack usually, and then use syringe pump, is easy to cause secondary pollution like this; There is medicinal liquid residual at container bottom during general the suction, causes dosage inaccurate, simultaneously because breaking of ampoule brings injury also for easily the medical care operator.Equally, the powder pin need add injection liquid and redissolve, and in use also has same problem.
The utility model content
The technical problems to be solved in the utility model provides a kind of pre-filled injection, can overcome the deficiency in use of Traditional Packing in the past, is suitable for packing the injection with small volume of prostaglandin and derivant thereof.
This utility model is the pre-filled injection of a kind of prostaglandin and derivant thereof, adopts the inner container of pre-encapsulated injector as injection, it is characterized in that, said prefilled syringe divides band pin type and not with the pin type; With pin type pre-encapsulated injector structure be not: the overcoat open rearward end of hollow circular cylinder is with the gum cover sealed port on the conehead of front end; One piston is arranged in the overcoat, and piston is connected with push rod, and push rod has one section to be inserted in the overcoat; Band pin type pre-encapsulated injector structure is: the overcoat open rearward end of hollow circular cylinder, be with helmet on the conehead of front end, and the helmet front end is solid section, is coaxially installed with syringe needle on the helmet, syringe needle inserts solid section sealing pin hole of helmet; One piston is arranged in the overcoat, and piston is connected with push rod, and push rod has one section to be inserted in the overcoat; Whole with the encapsulation of plastic-aluminum bubble-cap after pouring into medicinal liquid.
Said overcoat volume is 1ml, 1.25ml, 1.5ml, 2ml, 2.5ml, 3ml and 5ml, according to the medical treatment and the market demand, and the use amount difference of various medicinal liquids, the specification of the pre-filled injection of prostaglandin of the present invention and derivant thereof can be diversified.
Can buy aseptic pre-encapsulated injector in the market, it had carried out cleaning, silication and sterilization process before list marketing, and sterile sealing, before liquid drug, keep aseptic condition, therefore can be directly used in the fill of carrying out prostaglandin and derivative injection thereof, program is simple, and is easy to use.
This utility model provides the pre-fill injection of a kind of prostaglandin and derivant thereof, comprises prostaglandin, romethamine, misoprostol etc.
The advantage that prefilled syringe is used for prostaglandin and derivative injection thereof mainly contains:
1. high-quality glass, plastics and rubber are guaranteed safe and reliable;
2. save the transfer of medicinal liquid from the glass packaging to the syringe, reduced the waste that medicine causes because of absorption;
3. prefilled syringe adopts the quantitatively mode of filling medicinal liquid, and it is more accurate to draw medicinal liquid by hand than medical personnel
4. can prevent cross-contamination or secondary pollution in the use;
5. easy and simple to handle, than using ampoule to save the time of half, be particularly suitable for the emergency treatment patient;
6. avoid the injury of glass ampule and medicinal liquid to medical personnel.
Because each above advantage, the pre-filled injection of prostaglandin and derivant thereof will have higher using value and prospect, and the pre-filled injection of therefore inventing this class medicine is necessary.
Description of drawings
Fig. 1 is the structural representation (band pin type) of a kind of prefilled syringe of the present utility model
Fig. 2 is the structural representation (not being with the pin type) of a kind of prefilled syringe of the present utility model
The specific embodiment
Further specify structure of the present utility model with embodiment below, but be not limited to protection domain of the present utility model.
Embodiment 1 in conjunction with the accompanying drawings 1 and the structure of accompanying drawing 2 explanation pre-filled injection of the present utility model.
The pre-filled injection of prostaglandin of the present utility model and derivant thereof is made up of prefilled syringe and medicinal liquid, and injection pours in the overcoat of hollow circular cylinder of pre-encapsulated injector.
Band pin type pre-encapsulated injector structure is seen Fig. 1.Among Fig. 1,1 is overcoat, and 2 is piston, and 3 is push rod, and 4 is syringe needle, and 5 is helmet, and 6 is medicinal liquid, and 7 is label, and 8 is the plastic-aluminum bubble-cap.Overcoat 1 is a hollow circular cylinder, is with helmet 5 on the conehead of front end, open rearward end; Be provided with the capping of a piston 2 as overcoat 1 herb liquid 7 in the hollow circular cylinder overcoat 1, can slide in overcoat 1 and seal, piston 2 is connected with push rod 3; Push rod 3 has part to be inserted in the overcoat 1; Syringe needle 4 is socketed in an end of overcoat 1, is inserted in the solid-end of helmet 5 to seal; Whole with 8 encapsulation of plastic-aluminum bubble-cap after charging into medicinal liquid.
Be not with pin type pre-encapsulated injector structure to see Fig. 2.Among Fig. 2,1 is overcoat, and 2 is piston, and 3 is push rod, and 5 is helmet, and 6 is medicinal liquid, and 7 is label, and 8 is the plastic-aluminum bubble-cap.Overcoat 1 is a hollow circular cylinder, is with helmet 5 on the conehead of front end and seals open rearward end; Be provided with the capping of a piston 2 as overcoat 1 herb liquid 7 in the hollow circular cylinder overcoat 1, can slide in overcoat 1 and seal, piston 2 is connected with push rod 3; Push rod 3 has part to be inserted in the overcoat 1; Whole with 8 encapsulation of plastic-aluminum bubble-cap after charging into medicinal liquid.
The preparation of the pre-filled injection of embodiment 2 romethamines of the present utility model
At first romethamine is mixed with solution, add an amount of osmotic pressure regulator and antiseptic, reach aseptic apyrogeneity through special handling, under ten thousand grades of workshop local laminar flows, pour in the prefilled syringe of sterilized band helmet 5, after adding piston 2 sealings, decals, the encapsulation of usefulness plastic-aluminum bubble-cap.
The specification of prefilled syringe can be used 1ml, 1.25ml, 1.5ml, 2ml, 2.5ml, 3ml and 5ml, selects according to the medical treatment and the market demand.
The medicinal liquid of embodiment 3 prefilled syringes packing
The romethamine injection among the injection replacement embodiment 2 such as prostaglandin, romethamine, beraprost sodium, iloprost, latanoprost, Bei Mei prostatitis element, travoprost, dinoprost, misoprostol can be used, the pre-filled injection of corresponding product can be obtained.
Claims (3)
1. the pre-filled injection of prostaglandin and derivant thereof, adopt precharging type syringe as inner container, it is characterized in that: described precharging type syringe is for band pin type with not with the syringe of pin type, wherein the structure with pin type precharging type syringe is: the overcoat of hollow circular cylinder (1) open rearward end, be with helmet (5) on the conehead of front end, helmet (5) front end is solid section, be coaxially installed with syringe needle (4) on the helmet (5), seal pin hole in solid section of syringe needle (4) insertion helmet, one piston (2) is arranged in the overcoat (1), piston (2) is connected with push rod (3), push rod (3) has one section to be inserted in the overcoat (1), and is whole with plastic-aluminum bubble-cap or plastic bag (8) encapsulation after pouring into medicinal liquid; The structure with pin type precharging type syringe is not: the overcoat of hollow circular cylinder (1) open rearward end, helmet (5) sealed port is housed on the front end conehead, one piston (2) is arranged in the overcoat (1), piston (2) is connected with push rod (3), push rod (3) has one section to insert in the overcoat (1), and is whole with plastic-aluminum bubble-cap or plastic bag (8) encapsulation after charging into medicinal liquid.
2. pre-filled injection according to claim 1, the volume that it is characterized in that described overcoat (1) is 1ml～5ml.
3. pre-filled injection according to claim 1 is characterized in that: described prostaglandin and derivant thereof are prostaglandin, romethamine, beraprost sodium, iloprost, latanoprost, Bei Mei prostatitis element, travoprost, dinoprost, misoprostol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009201097013U CN201612837U (en) | 2009-07-03 | 2009-07-03 | Pre-filling injection agent of prostaglandin and derivatives thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009201097013U CN201612837U (en) | 2009-07-03 | 2009-07-03 | Pre-filling injection agent of prostaglandin and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201612837U true CN201612837U (en) | 2010-10-27 |
Family
ID=42999209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009201097013U Expired - Lifetime CN201612837U (en) | 2009-07-03 | 2009-07-03 | Pre-filling injection agent of prostaglandin and derivatives thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201612837U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108578641A (en) * | 2018-06-29 | 2018-09-28 | 无锡济民可信山禾药业股份有限公司 | A kind of Prefilled preparation of clinical emergency treatment traditional Chinese medicine injection |
| CN111760129A (en) * | 2020-07-15 | 2020-10-13 | 太阳升(亳州)生物医药科技有限公司 | Ready-to-use prefilled argatroban injection product and preparation method thereof |
-
2009
- 2009-07-03 CN CN2009201097013U patent/CN201612837U/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108578641A (en) * | 2018-06-29 | 2018-09-28 | 无锡济民可信山禾药业股份有限公司 | A kind of Prefilled preparation of clinical emergency treatment traditional Chinese medicine injection |
| CN111760129A (en) * | 2020-07-15 | 2020-10-13 | 太阳升(亳州)生物医药科技有限公司 | Ready-to-use prefilled argatroban injection product and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20101027 |
|
| DD01 | Delivery of document by public notice | ||
| DD01 | Delivery of document by public notice |
Addressee: Beijing Huaxi Pharm. Co., Ltd. Document name: Notification of Expiration of Patent Right Duration |