CN202543185U - Germ-free operating device with vibrating mixing machine and centrifugal machine - Google Patents
Germ-free operating device with vibrating mixing machine and centrifugal machine Download PDFInfo
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- CN202543185U CN202543185U CN 201220040398 CN201220040398U CN202543185U CN 202543185 U CN202543185 U CN 202543185U CN 201220040398 CN201220040398 CN 201220040398 CN 201220040398 U CN201220040398 U CN 201220040398U CN 202543185 U CN202543185 U CN 202543185U
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/16—Vibrating; Shaking; Tilting
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/38—Caps; Covers; Plugs; Pouring means
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/50—Means for positioning or orientating the apparatus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/10—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by centrifugation ; Cyclones
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Abstract
The utility model relates to a germ-free operating device with a vibrating mixing machine and a centrifugal machine. The germ-free operating device comprises a table, a vibrating mixer, a centrifugal machine, an isolating door and an air filtering system, wherein the table comprises a germ-free cavity; the vibrating mixer is arranged in the germ-free cavity; and the centrifugal machine is arranged in germ-free accommodating space below a cover plate in the germ-free cavity. Through the implementation of the utility model, a mixing process and a centrifugation process for treating cells can be completed without germs, so that the cells can avoid being contaminated by the outside when treated.
Description
Technical field
The utility model relates to a kind of aseptic technique device with concussion mixing machine and whizzer, particularly relates to a kind of aseptic technique device with concussion mixing machine and whizzer that cell is handled that is used for.
Background technology
In recent years, the autologous fat shaping technique can be avoided the spinoff of some immunological rejections, therefore becomes the important trend of medical and beauty treatment industry gradually.But the general cell of environmental requirement that the autologous fat shaping technique is handled for adipocyte is handled more strict.Because if adipocyte is polluted, and the adipocyte that this is polluted is replanted in the patient, will make sufferer be subjected to infection, sclerosis or calcification ... the risk that waits, and then cause the failure of shaping when handling.
Polluted for fear of adipocyte, no matter be that general tube manipulation, constant temperature mixes or centrifugation step, all need in gnotobasis, carry out, all operations utensil all must be with the alcohol disinfecting mistake, and the personnel that operate also need its both hands clean.Therefore usually require in the aseptic technique platform, to carry out tube manipulation, and constant temperature mixes and the laboratory apparatus of centrifugation step also should be placed in the dust free chamber, in order to avoid adipocyte is polluted leaving the aseptic technique platform and move in the process of other laboratory apparatus.
For this reason, add that at the environment of dust free chamber the processing operation of carrying out adipocyte under the aseptic technique platform is only standard practice, but so will make the building of environment of handling adipocyte be set to this raising.In view of this, handle in order to make adipocyte can in the environment of perfectly sterile, carry out tube manipulation, constant temperature and centrifugal, hope to reduce building of gnotobasis again and be set to this, the utility model proposes a kind of novel asepsis operating gear that can meet the demand.
This shows that above-mentioned existing aseptic technique device obviously still has inconvenience and defective, and demands urgently further improving in structure and use.In order to solve the problem that the aseptic technique device exists; Relevant manufacturer there's no one who doesn't or isn't seeks solution painstakingly; But do not see always that for a long time suitable design is developed completion; And common product does not have appropriate structure to address the above problem, and this obviously is the problem that the anxious desire of relevant dealer solves.Therefore how to found a kind of aseptic technique device that has that volume is little, cost is low concurrently and can have the novel texture of comprehensive adjustment function when using with concussion mixing machine and whizzer; Real one of the current important research and development problem that belongs to, also becoming the current industry utmost point needs improved target.
Summary of the invention
The purpose of the utility model is; Overcome the defective that existing sterile working device exists; And a kind of sterile working device with concussion mixer and centrifuge of new structure is provided; Technical problem to be solved is that mixture length and the centrifugal flow process of handling cell are all accomplished under aseptic situation; To avoid cell in processing procedure, to suffer the pollution of external environment; And then the feasible sterile working device that is used for the cell processing, thereby be suitable for practicality more with concussion mixer and centrifuge.
The purpose of the utility model and to solve its technical problem be that technical scheme below adopting realizes.It that proposes according to the utility model comprises: a board, and this board comprises: an aseptic cavity, it has an opening; And a service platform, being arranged in this aseptic cavity, this service platform has a cover plate again, and is provided with an aseptic accommodation space in this under; One isolating door, it is arranged at this opening part, in order to close this opening; And an air filtering system, be arranged at the outside of this aseptic cavity and in this aseptic cavity, produce a circulating current; One shaking mixer is arranged in this aseptic cavity; And a whizzer, be arranged in this aseptic accommodation space; Wherein the surface of the surface of this cover plate and this service platform is positioned at the par height.
The purpose of the utility model and solve its technical problem and can also adopt following technical measures to come further to realize.
Aforesaid aseptic technique device with concussion mixing machine and whizzer, wherein said this shaking mixer further comprises a heating unit.
Aforesaid aseptic technique device with concussion mixing machine and whizzer, wherein said this shaking mixer is the revolving shaking mixer of a 360 deg.
Aforesaid aseptic technique device with concussion mixing machine and whizzer, wherein said this air filtering system comprises: at least one air intake vent, it is communicated with the lower side of this aseptic cavity to suck a dirty air; One air filter, its inlet end is communicated with this air intake vent, and this air filter is in order to filter this dirty air and to produce a cleaned air; And at least one air outlet, be communicated with the upper side of this aseptic cavity, in order to this cleaned air sent into this aseptic cavity and to be produced this circulating current.
Aforesaid aseptic technique device with concussion mixing machine and whizzer, wherein said its further comprises a liquid drainage system, this liquid drainage system comprises:
One drainage machine, it is arranged at a ccontaining cavity of this aseptic cavity below;
One waste fluid container, it is arranged at a side of this drainage machine and becomes a vacuum state via this drainage machine effect; And
One aseptic drainage catheter, it has a drainage end and a waste fluid container end, and this waste fluid container end is connected to this waste fluid container, and this aseptic drainage catheter is drawn waste liquid to this waste fluid container end via this drainage end.
Aforesaid aseptic technique device with concussion mixing machine and whizzer; Wherein said its further comprises a system; This system telecommunication connects and program-controlled this isolating door, this air filtering system, this shaking mixer and this whizzer, and a control panel of this system is arranged in this aseptic cavity.
Aforesaid aseptic technique device with concussion mixing machine and whizzer, wherein said this system further comprises a foot board unit, telecommunication connects this system and is arranged at this aseptic cavity external.
Aforesaid aseptic technique device with concussion mixing machine and whizzer, wherein said this isolating door further comprises a state detecting device, in order to the unlatching or the closing condition of this isolating door of sensing, and this state detecting device is electrically connected to this system.
Aforesaid aseptic technique device with concussion mixing machine and whizzer, wherein said this board further comprises a ultraviolet source, its inboard, top that is arranged at this aseptic cavity is in order to sterilization.
Aforesaid aseptic technique device with concussion mixing machine and whizzer, wherein said this board further comprises a lighting source, its top that is arranged at this aseptic cavity is inboard.
Aforesaid aseptic technique device with concussion mixing machine and whizzer, wherein said this whizzer and this shaking mixer provide electric power by same power system.
The utility model compared with prior art has tangible advantage and beneficial effect.By technique scheme, the aseptic technique device that the utlity model has concussion mixing machine and whizzer can reach suitable technical progress property and practicality, and has the extensive utility value on the industry, and it has advantage at least:
1, shaking mixer and whizzer and aseptic technique board are combined, to save the experimental implementation space.
2, can in same aseptic technique board, accomplish tube manipulation, mixing and centrifugation step, avoid cell moving and suffer the pollution of external environment between different instruments, more can reduction equipment build and be set to this.
In sum, the utility model is a kind of aseptic technique device with concussion mixing machine and whizzer, and it comprises: a board; One shaking mixer; An and whizzer.The utility model mainly is will reach mixture length and the centrifugal flow process of handling cell are all accomplished under aseptic situation, in treating processes, suffers the pollution of external environment to avoid cell.The utility model has apparent progress technically, and has tangible positively effect, really is a novelty, progress, practical new design.
Above-mentioned explanation only is the general introduction of the utility model technical scheme; In order more to know the technique means of understanding the utility model; And can implement according to the content of specification sheets, and for let the above-mentioned of the utility model with other purpose, feature and advantage can be more obviously understandable, below special act preferred embodiment; And conjunction with figs., specify as follows.
Description of drawings
Fig. 1 is a kind of stereographic map with aseptic technique device of concussion mixing machine and whizzer of the utility model embodiment.
Fig. 2 is a kind of frontview with aseptic technique device of concussion mixing machine and whizzer of the utility model embodiment.
Fig. 3 is a kind of side-view with aseptic technique device of concussion mixing machine and whizzer of the utility model embodiment.
Fig. 4 is the enlarged view of the aseptic cavity of Fig. 1.
Fig. 5 is the stereographic map of a kind of shaking mixer of the utility model embodiment.
Fig. 6 is the stereographic map of a kind of whizzer of the utility model embodiment.
10: aseptic technique device with concussion mixing machine and whizzer
100: board 110: aseptic cavity
111: opening 112: service platform
113: cover plate 114: aseptic accommodation space
120: isolating door 130: air filtering system
131: circulating current 132: air intake vent
133: air filter 134: air outlet
140: ultraviolet source 150: lighting source
160: ccontaining cavity 200: shaking mixer
210: test-tube stand 211: bearing
212: test tube 220: axle center
300: whizzer 400: drainage system
410: drainage machine 420: waste fluid container
430: aseptic drainage catheter 431: drainage end
432: waste fluid container end 500: system
510: control panel 520: the foot board unit
Embodiment
For further setting forth the utility model is to reach technique means and the effect that predetermined goal of the invention is taked; Below in conjunction with accompanying drawing and preferred embodiment; To its embodiment of aseptic technique device, structure, characteristic and the effect thereof that proposes according to the utility model with concussion mixing machine and whizzer, specify as after.
Fig. 1 is a kind of stereographic map with aseptic technique device of concussion mixing machine and whizzer of the utility model embodiment.Fig. 2 is a kind of frontview with aseptic technique device of concussion mixing machine and whizzer of the utility model embodiment.Fig. 3 is a kind of side-view with aseptic technique device of concussion mixing machine and whizzer of the utility model embodiment.Fig. 4 is the enlarged view of the aseptic cavity of Fig. 1.Fig. 5 is the stereographic map of a kind of shaking mixer of the utility model embodiment.Fig. 6 is the stereographic map of a kind of whizzer of the utility model embodiment.
To shown in Figure 3, present embodiment is a kind of aseptic technique device 10 with concussion mixing machine and whizzer like Fig. 1, and it comprises: a board 100; One shaking mixer 200; An and whizzer 300.
Like Fig. 2 and shown in Figure 4, aseptic cavity 110 is a square hollow cavity, and it is positioned at the middle part of board 100.Aseptic cavity 110 has an opening 111; An and service platform 112.Service platform 112 is arranged in the aseptic cavity 110, and has a cover plate 113.Cover plate 113 belows are provided with an aseptic accommodation space 114 that is extended to form by aseptic cavity 110; And service platform 112 all can be processed by stainless steel with cover plate 113; The surface of the surface of its cover plate 113 and service platform 112 is positioned at the par height to increase the usage space that cell is handled, and the operation that cell is handled can be carried out on cover plate 113 and service platform 112.
Isolating door 120, it is arranged at opening 111 places, and isolating door 120 can be pull-type chilled glass door, and in order to close opening 111, the user can decide the degree of closing in its sole discretion.Isolating door 120 further can comprise a state detecting device (figure does not show), in order to the unlatching or the closing condition of sensing isolating door 120.
Like Fig. 3 and shown in Figure 4, air filtering system 130, it is arranged at the outside of aseptic cavity 110 and in aseptic cavity 110, produces a circulating current 131.Air filtering system 130 comprises: at least one air intake vent 132, air filter 133 and at least one air outlet 134.
As shown in Figure 5, shaking mixer 200 is arranged on the service platform 112 in the aseptic cavity 110.So that cell and reagent uniform distribution in vitro, it can be the revolving shaking mixer 200 of a 360 deg to shaking mixer 200 in order to cell and reagent are mixed.The operating method of shaking mixer 200 is for placing test tube 212 on the test-tube stand 210 that is provided with a bearing 211 earlier; And bearing 211 overlapped to an axle center 220 of shaking mixer 200; Via the drive of power system, test-tube stand 210 mixes with the content with test tube 212 around the rotation of axle center 220 360 degs again.Shaking mixer 200 may further include a heating unit (figure does not show), uses so that the cell of shaking mixer 200 is handled under temperature constant state.
Like Fig. 3 and shown in Figure 6, whizzer 300 is arranged in the aseptic accommodation space 114, when desire is used whizzer 300, needs elder generation that the cover plate 113 of top covering is started, and when not in use, cover plate 113 is built to increase the operating space of service platform 112 again.Wherein, whizzer 300 and shaking mixer 200 provide electric power by same power system.
To shown in Figure 3, present embodiment also can further comprise a liquid drainage system 400 like Fig. 1, and it comprises: a drainage machine 410, a waste fluid container 420 and an aseptic drainage catheter 430.Drainage machine 410 is arranged at a ccontaining cavity 160 of aseptic cavity 110 belows; Ccontaining cavity 160 is positioned at the downside position of board 100; 420 of waste fluid containers are arranged at a side of drainage machine 410; And aseptic drainage catheter 430 has a drainage end 431 and a waste fluid container end 432, and waste fluid container end 432 is connected to waste fluid container 420, and 431 at drainage end is in order to draw waste liquid such as cell treatment liq.
Present embodiment can further comprise a system 500 again, and system 500 telecommunications connect and program-controlled isolating door 120, air filtering system 130, shaking mixer 200 and whizzer 300.For example system 500 electrically connects with the state detecting device of isolating door 120, is sent to system 500 with unlatching or closing condition with isolating door 120, and system 500 can according to the unlatching of the closing condition control air filtering system 130 of isolating door 120.
One control panel 510 of system 500 is arranged in the aseptic cavity 110; So that the operator directly controls setting in aseptic cavity 110; Must both hands be exposed in the non-sterile environment, in order to avoid both hands are infected with dirty and are influenced operating result in order to control setting.In addition; System 500 further comprises a foot board unit 520; Its telecommunication connection control system 500 also is arranged at outside the aseptic cavity 110; In order to utilize foot board mode setting control system 500, can carry out cell simultaneously in order to the operator and handle and control setting and avoid both hands to be exposed in the non-sterile environment.
The design that in the present embodiment shaking mixer and whizzer and aseptic technique board is combined can make tube manipulation, mixing and the centrifugation step of cell all in gnotobasis, carry out, and avoids cell to suffer the pollution of external environment.Therefore in addition, do not need to be provided with in addition dust free chamber and reduce cell contamination, can significantly reduce experimental implementation space and reduction equipment and build and be set to this.
The above; It only is the preferred embodiment of the utility model; Not being that the utility model is done any pro forma restriction, though the utility model with the preferred embodiment exposure as above, yet is not in order to limit the utility model; Anyly be familiar with the professional and technical personnel; In not breaking away from the utility model technical scheme scope, make a little change or be modified to the equivalent embodiment of equivalent variations when the technology contents of above-mentioned announcement capable of using, be the content that does not break away from the utility model technical scheme in every case;, all still belong in the scope of the utility model technical scheme any simple modification, equivalent variations and modification that above embodiment did according to the technical spirit of the utility model.
Claims (11)
1. one kind has the aseptic technique device that shakes mixing machine and whizzer, it is characterized in that it comprises:
One board, this board comprises:
One aseptic cavity, it has an opening; And a service platform, being arranged in this aseptic cavity, this service platform has a cover plate again, and is provided with an aseptic accommodation space in this under;
One isolating door, it is arranged at this opening part, in order to close this opening; And
One air filtering system is arranged at the outside of this aseptic cavity and in this aseptic cavity, produces a circulating current;
One shaking mixer is arranged in this aseptic cavity; And
One whizzer is arranged in this aseptic accommodation space;
Wherein the surface of the surface of this cover plate and this service platform is positioned at the par height.
2. the aseptic technique device with concussion mixing machine and whizzer according to claim 1 is characterized in that this shaking mixer further comprises a heating unit.
3. the aseptic technique device with concussion mixing machine and whizzer according to claim 2 is characterized in that this shaking mixer is the revolving shaking mixer of a 360 deg.
4. the aseptic technique device with concussion mixing machine and whizzer according to claim 3 is characterized in that this air filtering system comprises: at least one air intake vent, and it is communicated with the lower side of this aseptic cavity to suck a dirty air; One air filter, its inlet end is communicated with this air intake vent, and this air filter is in order to filter this dirty air and to produce a cleaned air; And at least one air outlet, be communicated with the upper side of this aseptic cavity, in order to this cleaned air sent into this aseptic cavity and to be produced this circulating current.
5. the aseptic technique device with concussion mixing machine and whizzer according to claim 4 is characterized in that it further comprises a liquid drainage system, and this liquid drainage system comprises:
One drainage machine, it is arranged at a ccontaining cavity of this aseptic cavity below;
One waste fluid container, it is arranged at a side of this drainage machine and becomes a vacuum state via this drainage machine effect; And
One aseptic drainage catheter, it has a drainage end and a waste fluid container end, and this waste fluid container end is connected to this waste fluid container, and this aseptic drainage catheter is drawn waste liquid to this waste fluid container end via this drainage end.
6. according to the described aseptic technique device of arbitrary claim in the claim 1 to 5 with concussion mixing machine and whizzer; It is characterized in that it further comprises a system; This system telecommunication connects and program-controlled this isolating door, this air filtering system, this shaking mixer and this whizzer, and a control panel of this system is arranged in this aseptic cavity.
7. the aseptic technique device with concussion mixing machine and whizzer according to claim 6 is characterized in that this system further comprises a foot board unit, and telecommunication connects this system and be arranged at this aseptic cavity external.
8. the aseptic technique device with concussion mixing machine and whizzer according to claim 7; It is characterized in that this isolating door further comprises a state detecting device; In order to the unlatching or the closing condition of this isolating door of sensing, and this state detecting device is electrically connected to this system.
9. the aseptic technique device with concussion mixing machine and whizzer according to claim 8 is characterized in that this board further comprises a ultraviolet source, and its inboard, top that is arranged at this aseptic cavity is in order to sterilization.
10. the aseptic technique device with concussion mixing machine and whizzer according to claim 9 is characterized in that this board further comprises a lighting source, and its top that is arranged at this aseptic cavity is inboard.
11. the aseptic technique device with concussion mixing machine and whizzer according to claim 10 is characterized in that this whizzer and this shaking mixer provide electric power by same power system.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220040398 CN202543185U (en) | 2012-02-08 | 2012-02-08 | Germ-free operating device with vibrating mixing machine and centrifugal machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220040398 CN202543185U (en) | 2012-02-08 | 2012-02-08 | Germ-free operating device with vibrating mixing machine and centrifugal machine |
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| Publication Number | Publication Date |
|---|---|
| CN202543185U true CN202543185U (en) | 2012-11-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220040398 Expired - Fee Related CN202543185U (en) | 2012-02-08 | 2012-02-08 | Germ-free operating device with vibrating mixing machine and centrifugal machine |
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| CN (1) | CN202543185U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107362175A (en) * | 2017-08-01 | 2017-11-21 | 翟跃中 | A kind of Autologous arterial blood purification liquid ejection preparation and its preparation and application |
-
2012
- 2012-02-08 CN CN 201220040398 patent/CN202543185U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107362175A (en) * | 2017-08-01 | 2017-11-21 | 翟跃中 | A kind of Autologous arterial blood purification liquid ejection preparation and its preparation and application |
| CN107362175B (en) * | 2017-08-01 | 2020-09-08 | 成都清科生物科技有限公司 | Liquid injection preparation for purifying autologous arterial blood and preparation and application thereof |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20121121 Termination date: 20190208 |
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| CF01 | Termination of patent right due to non-payment of annual fee |