CN202526572U - Separation flexible bag applied to blood continuous centrifugal separation system - Google Patents
Separation flexible bag applied to blood continuous centrifugal separation system Download PDFInfo
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- CN202526572U CN202526572U CN2012200053062U CN201220005306U CN202526572U CN 202526572 U CN202526572 U CN 202526572U CN 2012200053062 U CN2012200053062 U CN 2012200053062U CN 201220005306 U CN201220005306 U CN 201220005306U CN 202526572 U CN202526572 U CN 202526572U
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Abstract
The utility model relates to a separation flexible bag applied to a blood continuous centrifugal separation system. Blood continuous centrifugal separation is conducted inside a curved solid container. The inside of the curved solid container is provided with a separation cavity gap which is in a curved solid structure. An outer wall curved surface of the separation cavity gap projects a shadow on a flat surface perpendicular to a rotation shaft, and curved lines of the projected shadow are a plurality of sections of spiral lines. The separation flexible bag is installed inside the separation cavity gap, is made of soft medical materials, is in a rectangle structure, and comprises a bag body and a pipeline connected with the bag body. A long side of the bag body is provided with a blood plasma pipeline, a full blood pipeline and a blood cell pipeline which are all communicated with the inside and the outside. The blood plasma pipeline, the full blood pipeline and the blood cell pipeline are arranged on the long side of the bag body in sequence. The separation flexible bag applied to the blood continuous centrifugal separation system has the advantages of being simple in structure, capable of achieving the continuous centrifugal separation of blood on a centrifugal separation device, high in separation efficiency, and low in cost.
Description
Technical field
This utility model relates to the blood separation technology, particularly is applied to the soft bag of separation on the continuous centrifugal formula blood separation equipment.
Background technology
No matter be scientific research or clinical medicine practice or commercial production; And more conditions, all need be with blood separation, as going out single component from separation of whole blood; Usually use centrifuging from blood, to isolate various single components, be used for occasions such as clinical treatment, scientific research or preparation raw material.Modal is that whole blood is isolated erythrocyte, granulocyte, mononuclear cell, platelet and blood plasma through centrifugal separation system, and erythrocyte and cleaning mixture are isolated in the FRC washing after maybe will thawing.
The operation principle of continuous centrifugal separation system is: the primary structure of said system includes centrifuge, infusion pump and control device; Through the infusion pipeline that is connected with infusion pump blood is introduced on the centrifuge in the soft bag in the knock-out drum; The high speed rotating knock-out drum; And this soft bag synchronous high-speed rotation of drive; The different effects that blood in it receives centrifugal force field causes visible components such as blood plasma and blood cell to do the centrifugal sedimentation campaign, and by the big or small layering of density or proportion or sedimentation coefficient separately; When reaching sedimentation equilibrium, arrange each the single component layer that forms concentric circles from radial periphery to axle center by the density height to low enrichment, utilize infusion pump more isolating single component layer to be extracted then.
The blood single component realizes that in this system continuous acquisition is rotary power to be provided and to play the effect of continuous input and extraction through airtight flexible pipe; The soft bag that separates in one end of flexible pipe and the knock-out drum is communicated with; With the knock-out drum high speed rotating, therefore the other end of flexible pipe is fixed on the support; Flexible pipe one end rotates an end to be fixed; There is a coil arrangement to realize that flexible pipe untwists wherein and twines, make under rotation status, can whole blood be inputed in the knock-out drum of rotation, and in the knock-out drum of rotation, extract single components such as blood plasma and blood cell out.Knock-out drum, i.e. separator disk, with the coil arrangement realization combining blood continuous centrifugal separate.
What relate to the separator disk that is applied on the blood continuous centrifugal separation equipment and coil arrangement in the prior art mainly contains U.S. Pat 5360542.In this patent, separator disk be one columnar structured, be called knock-out drum, a columnar lacuna is arranged in it, soft bag is placed on the centrifugalize that realizes blood in the circular lacuna; Coil arrangement includes underframe; Rotatable top-support suspends knock-out drum in midair on the top-support, a flexible pipe extend into the knock-out drum bottom after lateral two bearings of top-support are fixedly passed at the cabinet place; The end of its flexible pipe is a square spigot, extend in the square groove of knock-out drum central axis.Flexible pipe is a hollow structure, and several transfer pipelines are arranged in it, realizes that simultaneously power provides and the liquid conveying function.Based on above-mentioned structure, power makes top-support rotation, drives flexible pipe and untwists and produce torque forces, and this power is transferred to knock-out drum make it to produce in the same way and rotate, and then realize the separation process of blood continuous centrifugal.
Disclosed the separator disk of other a kind of version in the one Chinese patent application 200710046991.7.Point out in this patent: the separator disk on the many cells composition mixing material piece-rate system; Comprise durable hard-caked sediment dish and disposable soft bag; The circular discs of forming by inner core and base on the hard-caked sediment dish; Between inner core and base, form one section around this hard-caked sediment one week of dish circle core shaft and continuous lacuna that stem and afterbody do not seal, soft bag is for being provided with single cavity configuration of liquid inlet and outlet pipe, and this soft bag can be inserted in the described lacuna.Because everywhere centrifugal force is inconsistent in the described continuous lacuna, therefore under the centrifugal force continuous action, each composition of mixing material is the segmentation distribution in soft bag, can in above-mentioned segmentation, extract corresponding single component.Above-mentioned inner core is equivalent to described interior cylinder, base is equivalent to described outer cylinder.Above-mentioned hard-caked sediment dish that is to say separator disk.
No matter be foreign patent or domestic patent, all adopted separator disk to add the mode of soft bag, soft bag is disposable consumptive material parts.Because the mentality of designing of blood separation is different, and the former is a concentric design, and the latter is non-concentric design, the latter's separation efficiency improves a lot than the former the separator disk of these two kinds of forms in actual use.Though the latter is comparatively ingenious with the design that separates soft bag at hard-caked sediment dish, and certain effect is arranged in practice, but still the leeway of the design of improving is arranged.
The utility model content
This utility model purpose is to provide the separation on a kind of blood continuous centrifugal separation system soft bag.The soft bag of the separation of this utility model is intended to improve the separation efficiency of blood; Realize successive, hermetic, safe, high efficiency blood separation process; Obtain the pollution-free blood plasma of high clarity, can improve the efficient of blood separation, reduce the use cost of the medical disposable material of separating plasma.
In order to reach above-mentioned utility model purpose, this utility model provides following technical scheme:
A kind of soft bag of separation that is applied on the blood continuous centrifugal separation system; It is characterized in that, be provided with the curved body container in the described continuous piece-rate system, be provided with the separation lacuna in the curved body; Be provided with one in the described separation lacuna and separate soft bag; The separation process of blood continuous centrifugal is accomplished in the soft bag of said separation, and said separation lacuna is the curved body that includes outer wall and inwall, and the outer wall curved surface of this separation lacuna is a helix in the plane Projective Curve perpendicular to rotating shaft.
The above-mentioned soft bag of separation that is applied on the blood continuous centrifugal separation system comprises bag and the pipeline that is attached thereto; The soft bag of described separation bag is the rectangle structure that soft medical plastic is processed; One long limit of this bag is provided with and is communicated with inside and outside blood plasma pipeline, whole blood pipeline and blood cell pipeline, and described blood plasma pipeline, whole blood pipeline and blood cell pipeline are arranged in order on a long limit of bag.
In the above-mentioned soft bag of separation that is applied on the blood continuous centrifugal separation system; As a kind of way of realization; Described blood cell pipeline extend into and separates the end that soft bag is positioned at the long limit of the soft bag of separation; Described whole blood pipeline extend into to separate and is positioned at the middle part, same long limit of separating soft bag in the soft bag, and described blood plasma pipeline extend into to separate and is positioned at the other end that separates the same long limit of soft bag in the soft bag.
In the above-mentioned soft bag of separation that is applied on the blood continuous centrifugal separation system; As a kind of way of realization; Be sequentially arranged in all concentrated end that is positioned at of blood plasma pipeline, whole blood pipeline and blood cell pipeline on the bag one long limit; Separate being provided with bonding by bag film inwall and blood plasma passage, whole blood passage and blood cell passage that form in the soft bag, the opening part of passage lays respectively at an end, centre and the other end of bag.
In the above-mentioned soft bag of separation that is applied on the blood continuous centrifugal separation system; As a kind of way of realization; Be sequentially arranged in one of bag and grow all concentrated centres that are positioned at long limit of blood plasma pipeline, whole blood pipeline and blood cell pipeline on the limit; Separate being provided with bonding by bag film inwall and blood plasma passage, whole blood passage and blood cell passage that form in the soft bag, the opening part of passage lays respectively at an end, centre and the other end of bag.
In the above-mentioned soft bag of separation that is applied on the blood continuous centrifugal separation system; As a kind of way of realization, be sequentially arranged on the long limit of bag in blood plasma pipeline, whole blood pipeline and the blood cell pipeline, blood plasma pipeline and whole blood pipeline are positioned at the end that bag is grown the limit; The blood plasma pipeline is opened on an end of bag; The blood cell pipeline is positioned at and is opened on the other end on this length limit, separates to be provided with bonding by bag film inwall and whole blood passage that form in the soft bag, and it is opened in the middle of the bag.
The separation process of blood in the soft bag of above-mentioned separation is following:
The first step, in the centrifugal lacuna of high speed centrifugation rotation, blood flows from the whole blood pipeline along the inwall that separates soft bag to the higher far-end of centrifugal force, and piles up gradually at the far-end of centrifugal lacuna;
Second step; In the whole blood banking process; Being deposited in the outermost whole blood of centrifugal lacuna composition receives centrifugal forces affect and begins and separate; Isolated main component is blood plasma and blood cell, and wherein blood cell is piled up to the blood inlet of whole blood pipeline at far-end, and blood plasma is piled up to blood inlet on the direction that blood cell is piled up;
In the 3rd step, the blood plasma near-end has whole blood to pile up simultaneously, when the blood plasma of piling up reaches the blood inlet position, will be mixed by the whole blood of new entering, and then form a chaotic region at the blood inlet of whole blood pipeline;
In the 4th step, the cumulative volume of whole blood, blood plasma and blood cell spread blood inlet in the chaotic region, and after the near-end that separates lacuna spread, the chaotic region area enlarged gradually, and the chaotic region near-end is because the relatively stable component separating that under the influence of centrifugal force, can begin;
The 5th step; When chaotic region whole blood, blood plasma and blood cell totally are full of whole centrifugal lacuna; Centrifugal lacuna near-end has formed the blood plasma district; Had the blood plasma that reaches singly adopt standard in the blood plasma district this moment, and the far-end of centrifugal lacuna has formed the blood cell district, and the blood cell that reaches the standard of singly adopting is then arranged in the blood cell district this moment;
In the 6th step, utilize the blood plasma pipeline in being embedded in the soft bag of separation that separates the lacuna, to extract plasma fraction, and in separating soft bag, inject new whole blood, the dynamic equilibrium that makes it reach input and extract through the whole blood pipeline;
Based on technique scheme, the existing isolation technics of this utility model has following technological merit:
1. blood gets into and separates soft bag back under action of centrifugal force, and blood cell, blood plasma are taken their own roads, do not disturbed mutually by the path that designs.Because such Channel Design, regional function design have been arranged, reclaim the process that does not stop, carries out continuously (referring to set up under the situation of right-hand man's passage) so just can realize blood sampling, centrifugalize, plasma collection, blood cell.
Because separate the rotating speed of soft bag have only Centrifuge Cup rotating speed about 40%, and adopt soft medical plastic to separate soft bag, hemocyte is difficult for impaired, simultaneously when the input and output balance, separates soft bag and can fully launch as far as possible and separate lacuna and fit fully.
3. the design of the soft bag of this separation, the extracorporeal circulation amount of blood are centrifugal cup type 1/3rd, can realize that the continuous centrifugal of blood separates, and it is simpler than Centrifuge Cup to separate the processing technology of soft bag, and cost is relatively low.
Description of drawings
Fig. 1 is the applied environment sketch map that this utility model separates soft bag.
Fig. 2 is the separator disk structural representation that this utility model separates soft bag.
Fig. 3 is the plane Projective Curve sketch map perpendicular to rotating shaft of this utility model separator disk Separation.
Fig. 4 is that input and output channel that this utility model separates soft bag is distributed in and separates two ends, soft bag bag one long limit and separate soft bag constructions design diagram with intermediary.
Fig. 5 is the concentrated soft bag constructions design diagram of separation that separates soft bag bag one long limit one end that is distributed in of input and output channel that this utility model separates soft bag.
Fig. 6 is the concentrated soft bag constructions design diagram of the soft bag of the separation bag one long intermediary separation in limit that is distributed in of input and output channel that this utility model separates soft bag.
Fig. 7 is that the blood plasma pipeline of the soft bag of this utility model separation is positioned at an end that separates soft bag bag one long limit with the whole blood pipeline, and the blood cell pipeline is positioned at the soft bag constructions design diagram of separation of the bag other end.
Fig. 8 is that blood has just got into the sketch map that flows to that separates soft bag among this utility model embodiment 1.
Fig. 9 is that blood is full of the sketch map that flows to that separates before soft bag among this utility model embodiment 1.
Figure 10 is that blood is full of the sketch map that flows to that separates after soft bag among this utility model embodiment 1.
Figure 11 is that blood has just got into the sketch map that flows to that separates soft bag among this utility model embodiment 2.
Figure 12 is that blood is full of the sketch map that flows to that separates before soft bag among this utility model embodiment 2.
Figure 13 is that blood is full of the sketch map that flows to that separates after soft bag among this utility model embodiment 2.
The specific embodiment
Come the soft bag that separates that is applied on the continuous piece-rate system of blood of this utility model is done further elaboration in detail with concrete embodiment below in conjunction with accompanying drawing; In the hope of operation principle and the workflow of understanding this utility model more lucidly, but can not limit the protection domain of this utility model with this.
This utility model relates to the soft bag of separation on the continuous piece-rate system of a kind of blood.This application that separates soft bag is based on following principle:
Place one to have the separation container that separates lacuna blood,, utilize the density size of composition in centrifugal force difference and the blood of zones of different in the separation container, thereby blood plasma in the blood and other visible components are separated through this separation container of high speed rotating.The shape of this lacuna includes the curved body of outer wall and inwall, and the separation container that contains this curved body lacuna is called the curved body separation container, can reach the purpose of blood constituent high-efficiency and continuous centrifugalize through the application of this container.The outer wall curved surface of above-mentioned separation lacuna curve of projection on perpendicular to the plane of rotating shaft is the multistage helix, and is as shown in Figure 3.The structure of curved body container includes the separation lacuna of curved body form, and this Vessel Design is a disc-shaped structure, can be referred to as separator disk, and is as shown in Figure 2.Cylinder 1 and 2 two parts of outer cylinder in this separator disk comprises.Interior cylinder 1 removably is fixed in the inner chamber of outer cylinder 2, leaves certain gap between the internal chamber wall of outer cylinder 2 and the lateral wall of interior cylinder, and this space is exactly the separation lacuna 3 on the separator disk.
Hold the soft bag 4 of separation of once property use in it, the separation process of blood continuous centrifugal is carried out in separating soft bag.
Blood separation process in separating soft bag is following:
The first step, in the centrifugal lacuna 3 of high speed centrifugation rotation, blood separates in the soft bag from the blood inlet input through whole blood pipeline 6, flows to the higher far-end of centrifugal force along the inwall that separates soft bag, and piles up gradually at the far-end of centrifugal lacuna;
Second step; In the whole blood banking process; Being deposited in the outermost whole blood of centrifugal lacuna composition receives centrifugal forces affect and begins and separate; Isolated main component is blood plasma and blood cell, and wherein blood cell is piled up to the blood inlet of whole blood pipeline at far-end, and blood plasma is piled up to blood inlet on the direction that blood cell is piled up;
In the 3rd step, when the blood plasma of piling up reaches the blood inlet position, will be mixed by the whole blood of new entering, and then near the blood inlet of whole blood pipeline, form a chaotic region;
In the 4th step, the cumulative volume of whole blood, blood plasma and blood cell spread blood inlet in the chaotic region, and after the near-end that separates lacuna spread, the chaotic region area enlarged gradually, and the chaotic region near-end is because the relatively stable component separating that under the influence of centrifugal force, can begin;
The 5th step; When chaotic region whole blood, blood plasma and blood cell totally are full of whole centrifugal lacuna; Centrifugal lacuna 3 near-ends have formed the blood plasma district; Had the blood plasma that reaches singly adopt standard in the blood plasma district this moment, and the far-end of centrifugal lacuna 3 has formed the blood cell district, and the blood cell that reaches the standard of singly adopting is then arranged in the blood cell district this moment;
In the 6th step, utilize blood plasma passage 8 in being embedded in the soft bag 4 of the separation that separates the lacuna, to extract plasma fraction, and in separating soft bag 4, inject new whole blood from blood inlet through whole blood pipeline 6, the dynamic equilibrium that makes it reach input and extract;
The soft bag 4 of described disposable separation is a kind of flat bag shaped structures that have a plurality of liquid transmission pipelines, and Fig. 4, Fig. 5, Fig. 6, Fig. 7 are the deployed configuration sketch maps of the soft bag 4 of the separation of several kinds of forms in this utility model.The soft bag 4 of said separation is formed with three pipelines that are connected with bag by separating soft bag bag; Wherein, separating soft bag bag is rectangular soft medical plastic bag; Being aligned in sequence with three pipes that are communicated with inside and outside the bag on the soft bag of this separation bag one long limit, promptly be respectively blood plasma pipeline 5, whole blood pipeline 6 and blood cell pipeline 7.
As shown in Figure 5, described blood plasma pipeline 5 extend into to separate and is positioned at the other end that separates soft bag one long limit in the soft bag 4, and just for separating the blood plasma district in the lacuna 3, blood plasma pipeline 5 is used for extracting isolated blood plasma from separating soft bag 4 in the zone at these blood plasma pipeline 5 places.Described whole blood pipeline 6 extend into to separate and is positioned at the middle part, a long limit of separating soft bag 4 in the soft bag 4, and just for separating the chaotic region in the lacuna 3, whole blood pipeline 6 is used for carrying whole blood to separating soft bag 4 in the zone at these whole blood pipeline 6 places.Described blood cell pipeline 7 extend into and separates the end that soft bag is positioned at the long limit of the soft bag of separation, and the zone at this blood cell pipeline place just is the blood cell district in the separation lacuna 3, and blood cell pipeline 7 is used for extracting isolated blood cell from separating soft bag 4.
As shown in Figure 6; Described blood plasma pipeline 5, whole blood pipeline 6 and blood cell pipeline 7 are arranged in order on a long limit of bag; An and all concentrated end that is positioned at this length limit; Separate being provided with bonding by bag film inwall and blood plasma passage 8, whole blood passage 9 and blood cell path 10 that form in the soft bag, the opening part of passage lays respectively at blood plasma district, chaotic region and the blood cell district that separates lacuna 3.
Described blood plasma pipeline 5, whole blood pipeline 6 and blood cell pipeline 7 are arranged in order on a long limit of bag; And all concentrated centre that is positioned at this length limit; Separate being provided with bonding by bag film inwall and blood plasma passage 8, whole blood passage 9 and blood cell path 10 that form in the soft bag 4, the opening part of passage lays respectively at blood plasma district, chaotic region and the blood cell district that separates lacuna 3.
As shown in Figure 7; Described blood plasma pipeline 5, whole blood pipeline 6 and blood cell pipeline 7 are arranged in order on a long limit of separating soft bag bag; Wherein blood plasma pipeline 5, whole blood pipeline 6 are positioned at an end on the long limit of bag; Blood cell pipeline 7 is positioned at the other end on this length limit, and this blood cell pipeline 7 is arranged in the blood cell district that separates lacuna 3, separates to be provided with bonding by bag film inwall and blood plasma passage 8, whole blood passage 9 that form in the soft bag 4; The opening part of blood plasma passage 8 is arranged in the blood plasma district that separates lacuna 3, and the opening of whole blood passage 9 is arranged in the chaotic region that separates lacuna 3.
In the continuous centrifugal of this utility model separates, when entering into, separates in the lacuna 3 blood, and the whole blood that contains the whole blood composition is filled completely whole separated space gradually.In filling process, receive the influence of different centrifugal force size, visible component such as the blood cell in the whole blood and blood plasma are separated gradually; In separated space from the low centrifugal force district of near-end to the high centrifugal force field of far-end, be rendered as the distribution of blood plasma, whole blood and blood cell, not separating whole blood of major part is being assembled at the separated space middle part; Low centrifugal force zone is called the separated space near-end; Be also referred to as the blood plasma district, the high centrifugal force zone is called far-end, is also referred to as the blood cell district.Above-mentioned process realizes that its concrete state is following in separating soft bag 4:
As separator disk high speed rotating under the drive of flexible axle of centrifugalize container, the structure of its whole centrifugal separation system and operation logic explain in patent application 201020293871.4, and be as shown in Figure 2, repeats no more here.Separator disk need be around the central shaft high speed rotating under the drive of flexible axle, for the centrifugalize of blood provides power.Flexible axle stretches into the central rotating shaft position that is connected and fixed on separator disk, for the centrifugal rotation of separation container provides power.
On the centrifugalize container, there is an intersection point central shaft of separator disk and separator disk bottom surface, and this intersection point is exactly the power resources point that separator disk rotates.In the time of when the whole blood that contains the whole blood composition gets into the soft bag of separation from the whole blood pipeline in, owing to the lacuna of the soft bag 4 of this separation with separator disk fits, so can think that blood has got in the separation lacuna 3 of separation container.The reason that the soft bag 4 of centrifugalize is set in separating lacuna 3 is to satisfy the repeatedly use of separator disk, and when using its separating blood, the soft bag 4 of the disposable separation that only replacement cost is lower gets final product at every turn, and the separator disk itself that replacement cost is higher again.
Be the specific embodiment of this utility model below, respectively detail the concrete application of the soft bag of separation of this utility model.
Embodiment 1
In the present embodiment, the concrete structure of the soft bag of separation is as shown in Figure 4.Can know by figure; The soft bag constructions of the separation of present embodiment is formed with the pipeline that is attached thereto by separating soft bag bag; Separating soft bag 4 is rectangular soft medical plastic bag, and a long limit of the soft bag 4 of this separation is provided with and is communicated with inside and outside blood plasma pipeline 5, whole blood pipeline 6 and blood cell pipeline 7.Fig. 8, Fig. 9, Figure 10 flow into, are full of before separating soft bag, are full of the sketch map that flows to that separates behind the soft bag for blood
Blood continuous centrifugal separation process: when the rotating speed of separator disk reaches design speed; Whole blood gets into through whole blood pipeline 6 and separates soft bag 4; The blood cell big in the action of centrifugal force lower density moves to the blood cell district that separates soft bag; Moving direction is among Fig. 8 shown in the arrow 11, accumulates in the port of blood cell pipeline 7 and is pumped continually by blood cell pipeline 7, and direction is among Fig. 8 shown in the arrow 13; Simultaneously the less blood plasma of quality is to gathering and pumped by blood plasma pipeline 5 apart from separating the nearer proximal end of soft bag rotating shaft, and direction is among Fig. 8 shown in the arrow 12.
Separate soft bag blood plasma pipeline 5, blood cell pipeline 7 and whole blood pipeline 6 in the present embodiment and lay respectively at the two ends and the centre position of separating soft bag 4, correspond respectively to that the blood cell that separates in the lacuna 3 is regional, chaos is regional and blood plasma is regional, and is more favourable to liquid flow in the bag.
In the present embodiment, the concrete structure that separates soft bag is as shown in Figure 6, can be known by figure; The soft bag of the separation of present embodiment is formed with the pipeline that is attached thereto by separating soft bag bag, and separating soft bag 4 is rectangular soft medical plastic bag, and blood plasma pipeline 5, whole blood pipeline 6 and blood cell pipeline 7 are arranged in order on a long limit of bag; An and all concentrated end that is positioned at this length limit; Separate soft bag 4 and be provided with bonding by bag film inwall and blood plasma passage 8, whole blood passage 9 and blood cell path 10 that form, the opening of blood plasma passage 8 is positioned at an end of bag, the corresponding blood plasma district that separates in the lacuna 3; The opening of whole blood passage 9 is positioned at the centre of bag; The corresponding chaotic region that separates in the lacuna 3, the opening of blood cell passage is positioned at the other end of bag, the corresponding blood cell district that separates in the lacuna 3.Figure 11, Figure 12, Figure 13 flow into, are full of before separating soft bag, are full of the sketch map that flows to that separates behind the soft bag for blood
The centrifugal blood separation process: when the rotating speed of centrifugalize dish reached design speed, whole blood continued to arrive the middle part of separating soft bag 4 through whole blood pipeline 6 through whole blood passage 9 openings, and flow direction is an arrow 11; Separating soft bag distal direction far away at the big blood cell of action of centrifugal force lower density to distance moves and builds up; The less blood plasma of quality builds up to the nearer proximal end of distance separation soft bag rotating shaft simultaneously, and along with the continuous input of whole blood, separation process continues to carry out; When the soft bag of separation is full of; Blood plasma satisfies the standard of gathering, and blood plasma is pumped by blood plasma pipeline 5 through blood plasma passage 8, and the flow direction in the blood plasma passage is an arrow 12; Blood cell is pumped by blood cell pipeline 7 through the blood cell path 10 under the extraction of pump simultaneously, and blood cell is an arrow 13 at the flow direction of blood cell passage.Whole blood, blood cell, blood plasma three speed are by the operation of predetermined ratio relation under the normal condition.
Three pipelines are concentrated and are arranged on the centre position of separating soft bag one long limit in the present embodiment, can realize the continuous separation of blood, help separating the installation and removal of soft bag.
Undoubtedly, the soft bag of the separation of this utility model also has the replacement of other structural designs and equivalent elements, is not limited to the structure composition that the foregoing description is mentioned.Generally speaking, the structural design of the soft bag of the separation of this utility model also comprises the variation that other it will be apparent to those skilled in the art that and substitutes.
Claims (5)
1. one kind is applied to the soft bag of separation on the blood continuous centrifugal separation system; It is characterized in that; The soft bag of this separation comprises bag and the pipeline that is attached thereto; The soft bag of described separation bag is the rectangle structure that soft medical plastic is processed, and a long limit of this bag is provided with and is communicated with inside and outside blood plasma pipeline, whole blood pipeline and blood cell pipeline, and described blood plasma pipeline, whole blood pipeline and blood cell pipeline are arranged in order on a long limit of bag.
2. a kind of soft bag of separation that is applied on the blood continuous centrifugal separation system according to claim 1; It is characterized in that; Described blood plasma pipeline extend into to separate and is positioned at an end that separates the same long limit of soft bag in the soft bag; Described whole blood pipeline extend into and separates the middle part, same long limit that is positioned at the soft bag of separation in the soft bag, and described blood cell pipeline extend into and separates the other end that soft bag is positioned at the long limit of the soft bag of separation.
3. a kind of soft bag of separation that is applied on the blood continuous centrifugal separation system according to claim 1; It is characterized in that; Be sequentially arranged in one of bag and grow all concentrated ends that are positioned at of blood plasma pipeline, whole blood pipeline and blood cell pipeline on the limit; Separate being provided with bonding by bag film inwall and blood plasma passage, whole blood passage and blood cell passage that form in the soft bag, the opening part of passage lays respectively at an end, centre and the other end of bag.
4. a kind of soft bag of separation that is applied on the blood continuous centrifugal separation system according to claim 1; It is characterized in that; Be sequentially arranged in all concentrated being positioned in the middle of the long limit of blood plasma pipeline, whole blood pipeline and blood cell pipeline on the bag one long limit; Separate being provided with bonding by bag film inwall and blood plasma passage, whole blood passage and blood cell passage that form in the soft bag, the opening part of passage lays respectively at an end, centre and the other end of bag.
5. a kind of soft bag of separation that is applied on the blood continuous centrifugal separation system according to claim 1; It is characterized in that be sequentially arranged in blood plasma pipeline, whole blood pipeline and the blood cell pipeline on the bag one long limit, blood plasma pipeline, whole blood pipeline are positioned at an end on the long limit of bag; Blood plasma pipeline opening part is positioned at an end of bag; The blood cell pipeline is positioned at and is opened on the other end on this length limit, separates to be provided with bonding by bag film inwall and whole blood passage that form in the soft bag, and it is opened in the middle of the bag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012200053062U CN202526572U (en) | 2012-01-09 | 2012-01-09 | Separation flexible bag applied to blood continuous centrifugal separation system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012200053062U CN202526572U (en) | 2012-01-09 | 2012-01-09 | Separation flexible bag applied to blood continuous centrifugal separation system |
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| CN202526572U true CN202526572U (en) | 2012-11-14 |
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| CN2012200053062U Expired - Lifetime CN202526572U (en) | 2012-01-09 | 2012-01-09 | Separation flexible bag applied to blood continuous centrifugal separation system |
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- 2012-01-09 CN CN2012200053062U patent/CN202526572U/en not_active Expired - Lifetime
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