CN202522565U - Blood analyzer - Google Patents

Blood analyzer Download PDF

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Publication number
CN202522565U
CN202522565U CN2011205646676U CN201120564667U CN202522565U CN 202522565 U CN202522565 U CN 202522565U CN 2011205646676 U CN2011205646676 U CN 2011205646676U CN 201120564667 U CN201120564667 U CN 201120564667U CN 202522565 U CN202522565 U CN 202522565U
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CN
China
Prior art keywords
detecting device
blood
controller
flow chamber
sample
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Expired - Fee Related
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CN2011205646676U
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Chinese (zh)
Inventor
叶小莉
林成栋
钱毅
黄恒荣
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FUZHOU AIDIKANG MEDICAL INSPECTION CO LTD
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FUZHOU AIDIKANG MEDICAL INSPECTION CO LTD
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Priority to CN2011205646676U priority Critical patent/CN202522565U/en
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Publication of CN202522565U publication Critical patent/CN202522565U/en
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Abstract

The utility model discloses a blood analyzer. The blood analyzer comprises a display unit and a determination unit, wherein the display unit can be connected with the determination unit in a communicating manner; the determination unit comprises a sample making device, a controller, a WBC (white blood cell) detector, an RBC (red blood cell) detector and an HGB (hemoglobin) detector; the sample making device, the WBC detector, the RBC detector and the HGB detector are connected with the controller; and a communication interface is arranged on the controller, and the communication interface is connected with the display unit. The device can display a distribution map of a reference example in a certain position, compare with the distribution map of an example with the pattern in the aspect of vision and further perform precise analysis on blood. The blood can be fast analyzed through the device, a report can be fast generated, and first-hand detailed information can be provided for patients and clients.

Description

Blood analyser
Technical field
The utility model relates to field of medical, relates in particular to a kind of blood analyser that can carry out Accurate Analysis to blood.
Background technology
Blood analyser, clinical cellanalyzer, blood cell analyser, cellanalyzer, the blood cell technology appearance claimed again.Blood analyser is not only all over the world, and all obtained popularization and application in China hospitals at different levels.It has not only improved the accuracy of experiment structure, and many experimental index also are provided, and diagnosis and the discriminating of disease played vital role.Blood analyser is that one of instrument is very widely used in the hospital clinical check; Blood test is meant blood routine examination; Be hand-manipulated, microscopic counting, it comprises red blood cell, haemoglobin, white blood cell count(WBC) and classification, platelet count etc., has 10 projects.The blood routine examination of being a patient the most skillfully, the most also want 10 minutes.
Along with science and technology development with rapid changepl. never-ending changes and improvements; Automatic hematology analyzer occurs; The technology of blood cell analysis also turns to the classification of present nothing from several years ago three classification; From two-dimensional space and then turn to three dimensions, the no sorting technique of modern cellanalyzer is many has simultaneously adopted advanced technology, like laser technology etc.
Nineteen forty-seven U.S. scientist Ku Erte has invented the patented technology with resistance law technology particle.He was applied to the achieving success of haemocyte technology with this technology again in 1956; Its principle is the characteristic according to the non-conduction of haemocyte; Be the basis with suspension haemocyte in the electrolyte solution the resistance variations that causes being detected through technological aperture; Carry out haemocyte technology and stereometry, this method is called electric-resistivity method goods Coulter principle.1962, first blood-counter system of China succeeded in developing in Shanghai.To the end of the sixties cellanalyzer can also measure the HGB haemoglobin except carrying out simultaneously the blood count.The seventies, the platelet count appearance comes out, the eighties, has developed leukocyte differential count.The nineties, developed the cellanalyzer that can carry out technology to reticulocyte, 5 classification and juvenile cell detect more maturation simultaneously, and development is called the blood cell analysis streamline.
The utility model content
The technical matters that the utility model mainly solves provides a kind of determinator that can carry out blood analysis accurately.
For solving the problems of the technologies described above, the technical scheme that the utility model adopts is: a kind of blood analyser is provided, and said blood analyser comprises display unit and determination unit, and said display unit is connected with said determination unit can be communicated by letter; Said determination unit comprises sample preparation device, controller, WBC detecting device, RBC detecting device and HGB detecting device; Said sample preparation device, WBC detecting device, RBC detecting device and HGB detecting device link to each other with controller; Said controller is provided with communication interface, and said communication interface is connected with display unit.
Wherein, said WBC detecting device is the optics flow cytometer, comprises forming first flow chamber and the semiconductor laser light resource of measuring the style flow of liquid.
Wherein, said RBC detecting device comprises that first container and second flow chamber are based on sheath stream DC detection platform.
Concrete, said first flow chamber and second flow chamber are that quartz, glass or the synthetic resin material of light transmission processed.
Concrete, said first flow chamber and second flow chamber are tubular structure.
Wherein, said HGB detecting device is provided with the diluted sample chamber and second container.
Wherein, said controller comprises control module, storage unit, reading unit, image output interface and communication interface; Said storage unit, reading unit, image output interface and communication interface all link to each other with control module.
Wherein, said storage unit comprises RAM, ROM and hard disk.
The beneficial effect of present embodiment:
The blood analyser that present embodiment provides; The data that this analyser is measured according to determination unit; Generate the distribution of particles figure of the contained example distribution of sample to be detected, the controller of determination unit can be controlled display unit and show the distribution of particles figure of above-mentioned style at certain display position, and shows with reference to the example distribution plan at above-mentioned certain position; Make it from visually can comparing, thereby blood is carried out Accurate Analysis with the example distribution plan of above-mentioned style.Can analyze blood fast through this device, produce report fast, for patient and client provide first-hand detailed data.
Description of drawings
Fig. 1 is the structural representation of the blood analyser of the utility model embodiment;
Embodiment
By the technology contents, the structural attitude that specify the utility model, realized purpose and effect, know clearly below in conjunction with embodiment and conjunction with figs. and give explanation.
See also Fig. 1, the structural representation of the cellanalyzer of the utility model, said blood analyser comprises display unit and determination unit, said display unit is connected with said determination unit can be communicated by letter; Said determination unit comprises sample preparation device, controller, WBC detecting device, RBC detecting device and HGB detecting device; Said sample preparation device, WBC detecting device, RBC detecting device and HGB detecting device link to each other with controller; Said controller is provided with communication interface, and said communication interface is connected with display unit.
The determination data that this analyser can record according to determination unit generates the distribution of particles figure that shows the contained example distribution of blood, and shows the reference particle distribution plan at certain display position, makes it from visually can comparing with the distribution plan of determination data.
Said determination unit is provided with the heparin tube placer of the heparin tube that can lay blood.Heparin tube is placed to the suction pan position of appointment, and determination unit inside is provided with the sample preparation device, and it has suction and moves the volumetric pipette of blood and the container of mixed configuration blood and reagent etc.Volumetric pipette is the tubulose of erectting up and down, and its front end is a tip shape, and volumetric pipette marine site syringe pump connects; Can rely on this syringe pump to inhale and tell certain amount of fluid; Volumetric pipette marine site mobile device connects simultaneously, can move forward and backward up and down respectively, and heparin tube is by rubber stopper seal; Available volumetric pipette gets the rubber plug that spike pierces is placed on the heparin tube of inhaling pan position, extracts a certain amount of blood from heparin tube.
The sample preparation device comprises container, a plurality of solenoid valve and membrane pump etc.Said container is used to prepare the mensuration style that supplies to measure red blood cell, blood platelet and mensuration haemoglobin.The sample preparation device is provided with the sheath liquid container, and this sheath liquid container is connected to the WBC detecting device through liquid flow path.
Said WBC detecting device is the optics flow cytometer, comprises forming first flow chamber and the semiconductor laser light resource of measuring the style flow of liquid.This WBC detecting device can use the semiconductor laser flow cytometry to measure leucocyte, and said first flow chamber is that the materials such as quartz, glass and synthetic resin with light transmission are processed, and is tubular structure, its inner stream for supplying mensuration style and sheath fluid to flow through.This first flow chamber has the thinner orifice of other parts of internal space ratio; Near this orifice of flow chamber is double-sleeve structure, and pipe is the sample nozzle in it, and this sample nozzle is connected with the liquid revealment of sample preparation device; Sample from then on sample nozzle spues; The outer space of sample nozzle is the stream that sheath fluid flows through, and this stream is connected with the aforesaid liquid stream, and the sheath fluid of sheath fluid supply for receptacles gets into orifice through liquid flow path.The sheath fluid that so offers first flow chamber flows around the mensuration sample that spues from the sample nozzle.And orifice makes a fluid stream of measuring sample become very thin, makes to measure next one the orifice that passes through of holding at sheath fluid of particles such as contained leucocyte, red blood cell in the sample.
In addition; Dispose semiconductor laser light resource in this WBC detecting device; To the orifice irradiating laser of flow chamber, the transmission lens system that has several lens to constitute between semiconductor laser light resource and the flow chamber, the parallel beam that this illumination lens system penetrates semiconductor laser light resource is assembled and is beam spot.On the light path that the semiconductor laser light resource straight line prolongs, there is a Transflective mirror relative with illumination lens system at a distance from flow chamber; The straight line light that semiconductor laser light resource penetrates is furnished with photodiode by the beam splitting mirror shading at the light path rear of beam splitting mirror.
The RBC detecting device can flow the DC detection method with sheath and measure RBC number and platelet counts.This RBC detecting device has second flow chamber, measures sample by first container to this flow chamber supply.When measuring red blood cell and blood platelet, in first container, dilution is mixed into formation determination sample in the blood, this mensuration sample offers second flow chamber with sheath fluid by the sample preparation device; In flow chamber, measure sample and form the flow that is held by sheath fluid, be provided with the sky of a band point pole in the stream of flow chamber, when the blood mononucleated cell in the sample when this hole is passed through; The dc impedance in portalling is detected in this hole, and electric signal is transported to controller, when haemocyte passes through the hole; Above-mentioned dc impedance can increase, therefore, and the information that this electric signal reaction haemocyte aloft passes through; To this, electric signal carries out signal Processing just can be counted red blood cell and blood platelet.
Said HGB detecting device is provided with the diluted sample chamber and second container; Said HGB detecting device can use SLS haemoglobin method to measure the hemochrome amount; The HGB detecting device is supplied sample by second container to it, when measuring haemoglobin, in second container, dilution and hemolytic agent is mixed into formation determination sample in the blood; This hemolytic agent has the character that the haemoglobin that makes in the blood transforms to the SLS-haemoglobin; Light emitting diode and photodiode receive, and the light of the high-absorbility wavelength that light emitting diode sends is prone to absorbed by the SLS-haemoglobin, and the diluted sample chamber makes with the good plastic material of light transmission.Therefore, photodiode can receive light emitting diode sends, the transmitted light that absorbs of only diluted sample basically.Photodiode is to controller output and receive the corresponding electric signal of light, and controller compares the absorbance of the dilution of this absorbance and prediction, calculates the haemoglobin value.
Controller receives the electric signal of said WBC detecting device, RBC detecting device and HGB detecting device, will represent that through communication facilities cell size, nucleus determination datas such as dyeability, erythrocyte number, platelet count and haemoglobin value big or small, cell are transferred to controller.
Said controller comprises control module, storage unit, reading unit, image output interface and communication interface; Said storage unit, reading unit, image output interface and communication interface all link to each other with control module.Said storer can read said reference particle distribution plan from this storer according to the demonstration indication of reference particle distribution plan, and the said reference particle distribution plan that the control display unit will read is shown to said certain display position.Said control module can be controlled the display mode of said display device in many ways, specifically comprises following method: control module is controlled example distribution plan and the reference particle distribution plan of said display unit at certain display position Alternation Display sample; Control module can be controlled said display unit; Make that one of them fades away from said certain display position along with the said sample distribution of particles figure that is presented at said certain display position and said reference particle distribution plan, another distribution of particles figure is engendered at said certain display position; Control module shows said reference particle distribution plan at said certain display position, makes it to be superimposed upon on the distribution of particles figure of said sample, and can distinguish with the distribution of particles figure of said sample.Control module is according to the login of reference particle distribution plan indication, with the distribution of particles figure of said sample as a reference distribution of particles figure deposit said storage unit in, follow said storage unit and preserve several reference particle distribution plans.
Control module can be carried out the computer program of computer program that is stored in the storage unit and the RAM that reads, and plays a role through the application program after carrying out.
Said storage unit comprises RAM, ROM and hard disk, and ROM is made up of ROM (read-only memory), PROM, EPROM, EEPROM etc., computer program that storage is carried out by control module and used data thereof etc.
RAM is made up of SRAM or DRAM etc., is used to read the program that is stored in ROM and hard disk, the work space in the time of can also carrying out these computer programs as control module.
The LIS system is housed on the said hard disk; The LIS system is that report speed produces slowly to laboratory sample information, object information typing trouble, and this system can accelerate information processing rate greatly; Printed report promptly and accurately is for client and patient provide first-hand detailed data.
The LIS system is can fast recording and print the system that sample detects information; This system adopts the intelligent linkage function; Rapidity, accuracy, integrality, synchronism to testing result have been carried out perfect annotation; Make things convenient for researchist and staff's typing, perfect platform is provided for the client provides accurate form.The a plurality of platforms of this system compatible, like Windows xp, windows 2000, and windows 2003.
On the display interface of this system, have a report and handle window, can directly inquire the detection result of specimen data through this window, carry out functions such as sample signal auditing; Also comprise sample typing window; Make things convenient for user's typing sample information through the typing window; Above this window, also have options such as exterior point, front end input, pass on or front end input sample, only need the scanned samples bar code if sample is an exterior point; Sample information will extract from exterior point or front end input table, has saved the trouble of typing again; Testing result typing window; This window has been realized the instrument bi-directional communication function, and instrument transmission project is automatically used has blue markings, after instrument detecting goes out the result; Can utilize automatically interface routine with result transmission in the LIS system, avoided the hidden danger of the manual input of reviewer; The sample information browse window shows all samples that detected the same day, clicks associated row, can show the detail and the testing result of this sample.
The above is merely the embodiment of the utility model; Be not thus the restriction the utility model claim; Every equivalent structure transformation that utilizes the utility model instructions and accompanying drawing content to be done; Or directly or indirectly be used in other relevant technical fields, all in like manner be included in the scope of patent protection of the utility model.

Claims (8)

1. blood analyser is characterized in that comprising: display unit and determination unit, and said display unit is connected with said determination unit can be communicated by letter;
Said determination unit comprises sample preparation device, controller, WBC detecting device, RBC detecting device and HGB detecting device; Said sample preparation device, WBC detecting device, RBC detecting device and HGB detecting device link to each other with controller; Said controller is provided with communication interface, and said communication interface is connected with display unit.
2. blood analyser according to claim 1 is characterized in that: said WBC detecting device is the optics flow cytometer, comprises forming first flow chamber and the semiconductor laser light resource of measuring the style flow of liquid.
3. blood analyser according to claim 1 is characterized in that: said RBC detecting device comprises that first container and second flow chamber are based on sheath stream DC detection platform.
4. according to claim 2 or 3 described blood analysers, it is characterized in that: said first flow chamber and second flow chamber are that quartz, glass or the synthetic resin material of light transmission processed.
5. blood analyser according to claim 4 is characterized in that: said first flow chamber and second flow chamber are tubular structure.
6. blood analyser according to claim 1 is characterized in that: said HGB detecting device is provided with the diluted sample chamber and second container.
7. blood analyser according to claim 1 is characterized in that: said controller comprises control module, storage unit, reading unit, image output interface and communication interface; Said storage unit, reading unit, image output interface and communication interface all link to each other with control module.
8. blood analyser according to claim 7 is characterized in that: said storage unit comprises RAM, ROM and hard disk.
CN2011205646676U 2011-12-29 2011-12-29 Blood analyzer Expired - Fee Related CN202522565U (en)

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Application Number Priority Date Filing Date Title
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015157976A1 (en) * 2014-04-17 2015-10-22 深圳迈瑞生物医疗电子股份有限公司 Cell analysis method, system and apparatus
CN105203458A (en) * 2015-10-23 2015-12-30 无锡溥汇机械科技有限公司 Image processing device of blood analyzer
CN107976383A (en) * 2018-01-10 2018-05-01 刘晓文 A kind of long-range blood cell analysis machine and its long-range blood cell analysis system
WO2021104499A1 (en) * 2019-11-29 2021-06-03 深圳市帝迈生物技术有限公司 Sample adding and mixing method and apparatus, and non-transitory computer readable storage medium

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015157976A1 (en) * 2014-04-17 2015-10-22 深圳迈瑞生物医疗电子股份有限公司 Cell analysis method, system and apparatus
CN105203458A (en) * 2015-10-23 2015-12-30 无锡溥汇机械科技有限公司 Image processing device of blood analyzer
CN107976383A (en) * 2018-01-10 2018-05-01 刘晓文 A kind of long-range blood cell analysis machine and its long-range blood cell analysis system
WO2021104499A1 (en) * 2019-11-29 2021-06-03 深圳市帝迈生物技术有限公司 Sample adding and mixing method and apparatus, and non-transitory computer readable storage medium

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20121107

Termination date: 20181229

CF01 Termination of patent right due to non-payment of annual fee