CN202401062U - Low-frequency electromagnetic-field cell treater - Google Patents
Low-frequency electromagnetic-field cell treater Download PDFInfo
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- CN202401062U CN202401062U CN 201120528654 CN201120528654U CN202401062U CN 202401062 U CN202401062 U CN 202401062U CN 201120528654 CN201120528654 CN 201120528654 CN 201120528654 U CN201120528654 U CN 201120528654U CN 202401062 U CN202401062 U CN 202401062U
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
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Abstract
The utility model relates to a low-frequency electromagnetic-field cell treater, which is capable of realizing controls of parameters such as magnetic induction intensity, frequency and types of magnetic field and the like and comprises a control unit, a signal conversion unit, a magnetic-field debugging circuit and a magnetic-field coil. A control signal output end of the control unit is connected with a control signal input end of the signal conversion unit, and a control signal output of the signal conversion unit is connected with an input end of the magnetic-field debugging circuit. An output end of the magnetic-field debugging circuit is connected with the magnetic-field coil, and a culture dish holder is arranged in the magnetic-field coil. Specific magnetic-field parameters can be selected according to experiment needs, cell materials are can be subjected to magnetic-field treatment, magnetic induction intensity and frequency of the magnetic field are adjustable, various types and waveforms of the magnetic field can be provided, magnetic induction intensity in the magnetic-field coil is uniform, and reliability of experiment results is guaranteed.
Description
Technical field
The utility model belongs to magnetic field biology experimental technique field, relates to a kind of low frequency electromagnetic field cell processing instrument of realizing multivariable control such as magnetic induction density, field frequency and magnetic field type.
Background technology
In recent decades; Through a large amount of both at home and abroad research and clinical experiment confirmation, magnetic therapy is to some disease, like disease such as osteoporosis, union of fracture, soft tissue injury, hyperlipidemia or wound good medical functions arranged; A large amount of Magnetotherapeutic apparatus have also appearred on medical facilities market; But existing electromagnetic therapy equipment is different because of manufacturer, and frequency that product adopted and magnetic induction density parameter also often have very big difference, and the setting of parameter lacks effective experimental basis.The screening of adopting the experiment of cell in vitro magnetic field treatment to carry out best EM field treatment parameter be a kind ofly save time, economic, efficient and way that condition is easy to control, after the experimentation on animals checking, just can be used for direct clinical through the parameter that the cell levels primary dcreening operation is confirmed.Yet present stage is very few about the research of cell magnetic field treatment instrument, lacks a kind of cell EM field processing instrument that can realize multivariable control.
The utility model content
The purpose of the utility model is to overcome the problem that prior art exists, and a kind of low frequency electromagnetic field cell processing instrument of realizing multivariable control such as magnetic induction density, field frequency and magnetic field type is provided.
For this reason, the utility model adopts following technical scheme:
A kind of low frequency electromagnetic field cell processing instrument; Comprise control unit, signal conversion unit, magnetic field debug circuit, magneticfield coil; The wave output terminal of said control unit connects the wave input terminus of signal conversion unit; The wave output terminal of signal conversion unit connects the input terminus of magnetic field debug circuit, and the output terminal of magnetic field debug circuit connects magneticfield coil; Be provided with the petridish dispenser in the said magneticfield coil.Signal conversion unit is accepted to be transferred to the magnetic field debug circuit from the numerary signal of control unit and after being converted into simulating signal.
Said magneticfield coil is in series by three groups of coils, and the number of turn of middle one group of coil is more than the coil of both sides.
Be provided with the magnetic induction density transmitter in the said magneticfield coil; Magneticfield coil is connected with current sensor and voltage sensor; Said magnetic induction density transmitter, current sensor and voltage sensor are connected with the feedback signal input terminus of signal conversion unit respectively, and the feedback signal output terminal of said signal conversion unit is connected with the feedback signal input terminus of control unit.Above-mentioned inductor block is given signal conversion unit with real-time detected magnetic field parameter signal feedback, and signal conversion unit feeds back to control unit after simulating signal is converted into numerary signal again.
Said control unit comprises a man machine operation interface, and said man machine operation interface comprises that magnetic induction density is regulated dialog box, frequency selects dialog box, waveform to select dialog box, waveform signal interface and time that dialog box is set.
The described magnetic field parameter of the utility model mainly refers to expose to the sun direction etc. and the comparison of pulsed magnetic field, alternating magnetic field and static magnetic field and the selection etc. of time, magnetic of exposing to the sun of magnetic induction density, field frequency, field waveform, magnetic.
The beneficial effect of the low frequency electromagnetic field cell processing instrument that the utility model provides is: can be according to the selected specific magnetic field parameter of experiment needs, and cell material is implemented magnetic field treatment; The magnetic induction density in magnetic field and field frequency accurate and adjustable, and multiple magnetic field type and field waveform can be provided; The magneticfield coil intrinsic inductance is even, has guaranteed reliable experimental result.
Description of drawings
Fig. 1 is the fundamental diagram of the utility model low frequency electromagnetic field cell processing instrument;
Fig. 2 is the scheme of installation of the utility model low frequency electromagnetic field cell processing instrument;
Fig. 3 is the main power circuit schematic diagram of the utility model magnetic field debug circuit;
Fig. 4 is the pilot circuit schematic diagram of the utility model magnetic field debug circuit;
Fig. 5 be among the embodiment in the magneticfield coil vertically-the magnetic induction density distribution plan of 400mm～400mm;
Fig. 6 be among the embodiment in the magneticfield coil vertically-the uniformity of magnetic field distribution plan of 60mm～60mm;
Fig. 7 be among the embodiment in the magneticfield coil radially-the uniformity of magnetic field distribution plan of 45mm～45mm.
Embodiment
Shown in Fig. 1～2; A kind of low frequency electromagnetic field cell processing instrument; Comprise control unit, signal conversion unit, magnetic field debug circuit, magneticfield coil 1, the wave output terminal of said control unit connects the wave input terminus of signal conversion unit, and the wave output terminal of signal conversion unit connects the input terminus of magnetic field debug circuit; The output terminal of magnetic field debug circuit connects magneticfield coil 1, is provided with petridish dispenser 2 in the magneticfield coil 1.Magneticfield coil 1 is in series by three groups of coils, and the number of turn of middle one group of coil is more than the coil of both sides.Be provided with the magnetic induction density transmitter in the magneticfield coil 1; Magneticfield coil 1 is connected with current sensor and voltage sensor; Magnetic induction density transmitter, current sensor and voltage sensor are connected with the feedback signal input terminus of signal conversion unit respectively, and the feedback signal output terminal of said signal conversion unit is connected with the feedback signal input terminus of control unit.Control unit comprises a man machine operation interface, and said man machine operation interface comprises that magnetic induction density is regulated dialog box, frequency selects dialog box, waveform to select dialog box, waveform signal interface and time that dialog box is set.
Shown in Fig. 3～4, the magnetic field debug circuit comprises main power circuit and pilot circuit, and main power circuit is made up of two groups of placed in-line full H bridge circuits, is specially a H bridge circuit and the 2nd H bridge circuit; The one H bridge circuit comprises a power module that is made up of X-former B1 and power amplifier module T11, T21, T31, T41, and the 2nd H bridge circuit comprises a power module that is made up of X-former B2 and power amplifier module T12, T22, T32, T42; Be provided with mode enable switch US1, US2 between power module and the power model, be used for the switching of pulsed operation and CW work; Pilot circuit comprises the driver module that is used for the driving power amplification module; Wherein driver module is made up of multi-channel PWM producer and multichannel IGBT driving mechanism; PWM generator can produce multiplex pulse; The IGBT driving mechanism amplifies the pulse that PWM generator produces, and produces multi-channel drive signal then and removes to drive each power amplifier module respectively.
The magnetic field type that magneticfield coil 1 produces is alternating magnetic field, pulsed magnetic field or static magnetic field, and the field waveform of generation is sine wave, choppy sea, square wave or zigzag wave, and the magnetic induction density in the magnetic field of generation is 0 ~ 20mT, and field frequency is 5 ~ 100Hz.
Magneticfield coil 1 longitudinal length is 270mm, and internal diameter is 100mm, can be positioned over common CO
2In the incubator 3.Shown in Fig. 5～7 (the initial point position is the magneticfield coil central point among the figure); Under switch-on regime, can produce one in 120 * 90 * 90mm scope of magneticfield coil 1 central zone and be close to uniform magnetic field; Uniformity of magnetic field＜1/1000 can guarantee that all cells in this scope all receives the processing of same magnetic field.
During work, there is the petridish of cell or biomaterial to be positioned on the petridish dispenser 2 cultivation, magneticfield coil 1 is arranged on CO
2In the incubator 3; Set required magnetic field parameter through man machine operation interface then; Control unit is transferred to signal conversion unit with this set information with digital signal form; By signal conversion unit numerary signal is converted into simulating signal and gives the magnetic field debug circuit with this analog signal transmission, the magnetic field debug circuit amplifies simulating signal and in view of the above magneticfield coil 1 is applied certain voltage, produces specific magnetic field by magneticfield coil 1 again; The electric current of the magnetic induction density in magnetic field and magneticfield coil 1 and voltage are through after magnetic induction density transmitter, current sensor and the voltage sensor induction; Transfer to signal conversion unit, this signal feeds back to control unit and carries out visualization display by man machine operation interface after being converted into numerary signal.
Claims (3)
1. low frequency electromagnetic field cell processing instrument; It is characterized in that; Comprise control unit, signal conversion unit, magnetic field debug circuit, magneticfield coil (1); The wave output terminal of said control unit connects the wave input terminus of signal conversion unit, and the wave output terminal of signal conversion unit connects the input terminus of magnetic field debug circuit, and the output terminal of magnetic field debug circuit connects magneticfield coil (1); Be provided with petridish dispenser (2) in the said magneticfield coil (1).
2. a kind of low frequency electromagnetic field cell processing instrument according to claim 1 is characterized in that said magneticfield coil (1) is in series by three groups of coils, and the number of turn of middle one group of coil is more than the coil of both sides.
3. a kind of low frequency electromagnetic field cell processing instrument according to claim 1; It is characterized in that; Be provided with the magnetic induction density transmitter in the said magneticfield coil; Magneticfield coil (1) is connected with current sensor and voltage sensor, and said magnetic induction density transmitter, current sensor and voltage sensor are connected with the feedback signal input terminus of signal conversion unit respectively, and the feedback signal output terminal of said signal conversion unit is connected with the feedback signal input terminus of control unit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120528654 CN202401062U (en) | 2011-12-16 | 2011-12-16 | Low-frequency electromagnetic-field cell treater |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120528654 CN202401062U (en) | 2011-12-16 | 2011-12-16 | Low-frequency electromagnetic-field cell treater |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202401062U true CN202401062U (en) | 2012-08-29 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201120528654 Expired - Fee Related CN202401062U (en) | 2011-12-16 | 2011-12-16 | Low-frequency electromagnetic-field cell treater |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202401062U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102517208A (en) * | 2011-12-16 | 2012-06-27 | 陈克明 | Low-frequency electromagnetic field cell treatment instrument |
| CN105675855A (en) * | 2016-01-21 | 2016-06-15 | 天津工业大学 | Low-frequency magnetic field generator for cell experiment researches |
| CN109939358A (en) * | 2019-04-16 | 2019-06-28 | 吉林大学 | A kind of low-frequency range broadband magnetic field-therapeutic instrument and its application method for oncotherapy |
-
2011
- 2011-12-16 CN CN 201120528654 patent/CN202401062U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102517208A (en) * | 2011-12-16 | 2012-06-27 | 陈克明 | Low-frequency electromagnetic field cell treatment instrument |
| CN105675855A (en) * | 2016-01-21 | 2016-06-15 | 天津工业大学 | Low-frequency magnetic field generator for cell experiment researches |
| CN109939358A (en) * | 2019-04-16 | 2019-06-28 | 吉林大学 | A kind of low-frequency range broadband magnetic field-therapeutic instrument and its application method for oncotherapy |
| CN109939358B (en) * | 2019-04-16 | 2020-11-10 | 吉林大学 | Low-frequency-band broadband magnetic field therapeutic apparatus for tumor treatment and application method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120829 Termination date: 20181216 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |