CN110123445B - High-frequency high-voltage circuit time-sharing multiplexing control device and multi-electrode radio frequency ablation system - Google Patents
High-frequency high-voltage circuit time-sharing multiplexing control device and multi-electrode radio frequency ablation system Download PDFInfo
- Publication number
- CN110123445B CN110123445B CN201910490444.0A CN201910490444A CN110123445B CN 110123445 B CN110123445 B CN 110123445B CN 201910490444 A CN201910490444 A CN 201910490444A CN 110123445 B CN110123445 B CN 110123445B
- Authority
- CN
- China
- Prior art keywords
- frequency
- speed
- voltage circuit
- time division
- division multiplexing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000007674 radiofrequency ablation Methods 0.000 title abstract description 26
- 238000002679 ablation Methods 0.000 claims description 59
- 229910001289 Manganese-zinc ferrite Inorganic materials 0.000 claims description 3
- JIYIUPFAJUGHNL-UHFFFAOYSA-N [O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[Mn++].[Mn++].[Mn++].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Zn++].[Zn++] Chemical compound [O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[Mn++].[Mn++].[Mn++].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Zn++].[Zn++] JIYIUPFAJUGHNL-UHFFFAOYSA-N 0.000 claims description 3
- 238000002955 isolation Methods 0.000 claims description 3
- 238000010586 diagram Methods 0.000 description 12
- 230000000694 effects Effects 0.000 description 7
- 230000005684 electric field Effects 0.000 description 5
- 150000002500 ions Chemical class 0.000 description 5
- 238000013153 catheter ablation Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 206010031264 Osteonecrosis Diseases 0.000 description 1
- 101100489713 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GND1 gene Proteins 0.000 description 1
- 101100489717 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GND2 gene Proteins 0.000 description 1
- 230000005672 electromagnetic field Effects 0.000 description 1
- 230000005674 electromagnetic induction Effects 0.000 description 1
- 230000005669 field effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00696—Controlled or regulated parameters
- A61B2018/0072—Current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1467—Probes or electrodes therefor using more than two electrodes on a single probe
Abstract
The invention discloses a high-frequency high-voltage circuit time-sharing multiplexing control device and a multi-electrode radio frequency ablation system, wherein the high-frequency high-voltage circuit time-sharing multiplexing control device comprises: the control end power supply access end, the on-off square wave controller, the high-speed on-off controller and the high-speed variable reactor; the control end power supply access end is electrically connected to the high-speed on-off controller through the on-off square wave controller, and the on-off square wave controller controls the voltage on-off frequency of the control end power supply access end loaded on the high-speed on-off controller according to the on-off control signal; the high-speed on-off controller is electrically connected with the primary of the high-speed variable reactor and controls the on-off frequency of current flowing through the primary of the high-speed variable reactor according to the voltage on-off frequency; the secondary of the high-speed variable reactor is electrically connected with an alternating current load circuit, and is conductive when the primary is conductive with current, and reactance is generated when the primary is non-conductive with current, so that the alternating current output by the high-frequency high-voltage alternating current output circuit can be multiplexed on each group of electrodes of the multi-electrode radio frequency ablation system in a time-sharing manner.
Description
Technical Field
The invention relates to a control device of a high-frequency high-voltage circuit and an electrode radio frequency ablation system using the control device, in particular to a time-sharing multiplexing control device of the high-frequency high-voltage circuit and a multi-electrode radio frequency ablation system.
Background
In the field of medical radio frequency ablation, the main mechanism of radio frequency ablation is the thermal effect. The radio frequency is high-frequency high-voltage alternating current with a certain frequency, and the current medical radio frequency mostly adopts the frequency of 300KHz-4000 KHz. When the radio frequency current flows through human tissue, positive ions and negative ions in cells quickly move due to the quick change of the electromagnetic field, so that the temperature of ablation parts is raised due to friction between the positive ions and the negative ions and other molecules, ions and the like in the cells, and the water inside and outside the cells is evaporated, dried, condensed and shed, so that aseptic necrosis is caused, and the aim of ablating the tissues is fulfilled.
Theoretically, the electrode with smaller area can provide larger current density and can ablate tissues more efficiently and rapidly, but in practical clinical application, tissues with certain intervals are often required to be ablated, the intervals of the tissues are slightly larger or are larger than the area of the ablation electrode by several times, such as cardiac ablation, tumor ablation, large blood vessel ligation and the like, and the electrode with smaller area cannot ablate tissues efficiently and rapidly. If the area of the ablation electrode is increased, the current density of the electrode is reduced, and if a better ablation effect is achieved, the output power of the device is increased, for example, the current large blood vessel ligation device needs to have the highest output power of 150W above due to the use of the large-area electrode. In cardiac ablation and tumor ablation operations, the device usually needs to be continuously loaded and operated for more than tens of seconds or even more than half an hour, if the area of an electrode of an ablation instrument is increased, the burden of high-voltage components in the device is increased, and therefore the reliability of the device is reduced.
In addition, the radio frequency ablation also needs to monitor the impedance change of the ablated tissue in real time, and the effect of ablation is judged through the impedance change of the ablated tissue. The ablation electrode with larger area can enlarge the area of the electrode contacting the tissue, and the ablation impedance can correspondingly reduce, so that the judgment of the ablation impedance is affected. If the cardiac ablation electrode is originally 1 pair of electrodes, but the number of the electrodes needs to be increased to 2 pairs or 3 pairs (which is equivalent to increasing the area of the electrodes to 2 times or 3 times of the area of 1 pair of electrodes), and a plurality of pairs of electrodes simultaneously output high-frequency high-voltage alternating current, although the area of the ablated tissue can be increased, the impedance of the ablated tissue can be reduced to half or one third of the original impedance, and the cardiac ablation judges the wall breaking degree through the impedance, so that the impedance is reduced, and the judgment of the wall breaking condition of equipment is affected.
Therefore, developing an electrode radiofrequency ablation device that does not increase the output power of the device, so as to reduce the burden of high-voltage components inside the device, ensure the reliability and service life of the device, and also does not increase the contact area between the electrode and the tissue, so as to ensure the accuracy of ablation impedance judgment, has become an urgent need in the art.
Disclosure of Invention
The main technical problem to be solved by the technical scheme is to provide a high-frequency high-voltage circuit time-sharing multiplexing control device and a multi-electrode radio frequency ablation system, wherein the multi-electrode radio frequency ablation system can perform time-sharing multiplexing control on high-frequency high-voltage alternating current output through the high-frequency high-voltage circuit time-sharing multiplexing control device so that multiple groups of electrodes with smaller areas can be operated in a time-sharing mode under the operating environment without increasing the output power of equipment, so that tissues with larger intervals or areas can be ablated, and meanwhile, the impedance of the ablated tissues can be accurately judged.
In order to solve the technical problem, the present technical solution provides a high-frequency high-voltage circuit time division multiplexing control device, which includes: the control end power supply access end, the on-off square wave controller, the high-speed on-off controller and the high-speed variable reactor; the control end power supply access end is used for accessing and isolating the control end power supply, the control end power supply access end is electrically connected to the high-speed on-off controller through the on-off square wave controller, and the on-off square wave controller is used for controlling the voltage on-off frequency of the control end power supply access end loaded on the high-speed on-off controller according to on-off control signals (such as square wave control signals); the high-speed on-off controller is electrically connected with the primary of the high-speed variable reactor and is used for controlling the on-off frequency of current flowing through the primary of the high-speed variable reactor according to the voltage on-off frequency; the secondary of the high-speed variable reactor is electrically connected with the alternating current load circuit, and is conductive when the primary of the high-speed variable reactor is conductive with current, and generates reactance when the primary of the high-speed variable reactor is non-conductive with current.
As another implementation of the technical scheme, the high-speed varactor is composed of a magnetic ring body, primary enameled wires and secondary enameled wires which are uniformly wound on the magnetic ring body, wherein the primary enameled wires wound on the magnetic ring body form the primary of the high-speed varactor, and the secondary enameled wires wound on the magnetic ring body form the secondary of the high-speed varactor. The secondary enameled wire reactance can be controlled by operating on-off current in the primary enameled wire.
As another implementation of the technical scheme, the manganese zinc ferrite with the material of the magnetic ring body being 36X23X15 is adopted, the primary enameled wire is 1.0mm in diameter and uniformly wound on the magnetic ring body for 15 circles, and the secondary enameled wire is 0.8mm in diameter and uniformly wound on the magnetic ring body for 30 circles.
As another implementation of the technical scheme, the high-speed on-off controller is composed of two N-type MOS tubes electrically connected with two ends of a primary of the high-speed transformer, wherein the positive electrode of the power supply access end of the control end is electrically connected with the on-off square wave controller and then electrically connected with the grid electrodes of the two N-type MOS tubes, the drain electrodes of the two N-type MOS tubes are respectively electrically connected with one end and the other end of the primary of the high-speed transformer, and the source electrodes of the two N-type MOS tubes are electrically connected with the negative electrode of the power supply access end of the control end. According to the characteristics of large current and high speed of the N-type MOS tube, the on-off square wave controller is utilized to control the on-off frequency of voltage (electric field) loaded between the grid electrode and the source electrode of the N-type MOS tube, so that the on-off frequency of current output of the drain electrode of the N-type MOS tube is controlled, and the on-off and the off of current in the primary stage of the high-speed transformer reactor are further controlled rapidly and stably.
As another implementation of the present technical solution, a diode is electrically connected between the drain and the source of the two N-type MOS transistors, respectively, wherein the source is electrically connected with the anode of the diode, and the drain is electrically connected with the cathode of the diode. The diode is used as a reverse (current) protection diode in the N-type MOS tube, and the speed of the diode is basically consistent with the on-off speed of the N-type MOS tube.
As another implementation of the technical scheme, the on-off frequency of the on-off control signal is 50Hz to 1KHz. That is, the on-off square wave controller controls the primary current of the high-speed varactor to be turned on and off 50 times to 1000 times per second.
As another implementation of the present embodiment, the inductance of the secondary of the high-speed varactor is 2.5mH. According to the operating frequency of the radio frequency ablation device is generally 460KHz, when the primary of the high-speed varactor is open (no current passes through the primary), the secondary of the high-speed varactor is connected in series in the ac load circuit, which is equivalent to connecting in series an inductance of 2.5mH, and the reactance of which is z=2pi fl=2x3.14x460000 x 2.5/1000=7.2kΩ.
In order to solve the above technical problem, the present technical solution further provides a multi-electrode rf ablation system electrically connected to a high-frequency high-voltage ac output circuit, the multi-electrode rf ablation system comprising: two isolated control end power supplies, at least two groups of high-frequency high-voltage circuit time division multiplexing control devices and at least two groups of ablation electrodes; each group of high-frequency high-voltage circuit time-sharing multiplexing control device comprises two high-frequency high-voltage circuit time-sharing multiplexing control devices; each set of ablation electrodes includes two ablation electrodes; the two isolation control end power supplies are respectively connected to the control end power supply access ends of the two high-frequency high-voltage circuit time-sharing multiplexing control devices of each group of high-frequency high-voltage circuit time-sharing multiplexing control devices; an output end of the high-frequency high-voltage alternating current output circuit is electrically connected with one end of a secondary side of a high-speed variable reactor of one high-frequency high-voltage circuit time division multiplexing control device in each group of high-frequency high-voltage circuit time division multiplexing control devices, and the other output end of the high-frequency high-voltage alternating current output circuit is electrically connected with one end of the secondary side of the high-speed variable reactor of the other high-frequency high-voltage circuit time division multiplexing control device in each group of high-frequency high-voltage circuit time division multiplexing control devices; each group of ablation electrodes is correspondingly connected with the other end of the secondary of the high-speed variable reactor of the two high-frequency high-voltage circuit time-sharing multiplexing control devices of each group of high-frequency high-voltage circuit time-sharing multiplexing control devices.
As another implementation of the technical scheme, the isolation control terminal power supply is a 12V direct current power supply. The control power supply (electric field) is used for controlling the on and off of the high-speed on-off controller.
As another implementation of the technical scheme, the square wave phase difference of the on-off control signals of the on-off square wave controllers of the high-frequency high-voltage circuit time-sharing multiplexing control devices of all groups is 360 degrees/the number of groups of the high-frequency high-voltage circuit time-sharing multiplexing control devices; the duty ratio of square wave waveform of on-off control signals of on-off square wave controllers of the high-frequency high-voltage circuit time division multiplexing control devices of all groups is 1/100% of the number of groups of the high-frequency high-voltage circuit time division multiplexing control devices. Therefore, the stable operation of time-sharing multiplexing of the plurality of groups of ablation electrodes of the multi-electrode radio frequency ablation system can be ensured.
According to the technical scheme, the number of the electrodes is increased to form a plurality of groups of electrodes, the high-frequency high-voltage alternating current output circuit is subjected to time division multiplexing through the high-frequency high-voltage circuit time division multiplexing control device, the output high-frequency high-voltage alternating current is subjected to time division multiplexing on each group of electrodes, the time interval of time division is extremely small and is 50 to more than 1000 times per second, only one group of electrodes works in each time division period, the output current density is not affected, the ablation impedance is not affected, and the method is macroscopically and effectively equal to that the same high-frequency high-voltage alternating current is applied to human tissues in a time division manner through the plurality of groups of electrodes. According to the method, the ablation effects of the plurality of groups of electrodes respectively and independently acting on the tissues can be accumulated, and finally, the ablation effects of the plurality of groups of electrodes simultaneously acting on the tissues are achieved.
Drawings
FIG. 1 is a block diagram of a high frequency high voltage circuit time division multiplexing control device of the present invention;
fig. 2 is a schematic diagram of a specific structure of a high-speed varactor according to the present invention;
FIG. 3 is a schematic diagram of a high-speed on-off controller according to the present invention;
FIG. 4 is a schematic diagram showing the alternating current flowing clockwise in the loop formed by the two N-type MOS transistors and the primary stage;
FIG. 5 is a schematic diagram showing an alternating current flowing counterclockwise in a loop formed by two N-type MOS transistors and a primary stage;
FIG. 6 is a schematic diagram of a multi-electrode RF ablation system having two sets of ablation electrodes;
FIG. 7 is a schematic diagram of a multi-electrode RF ablation system having three sets of ablation electrodes;
FIG. 8 is a waveform diagram of on-off control signals of each on-off square wave controller in a multi-electrode RF ablation system with two sets of ablation electrodes;
fig. 9 is a waveform diagram of on-off control signals of each on-off square wave controller in a multi-electrode radio frequency ablation system with three sets of ablation electrodes.
Symbol description in the drawings:
1. a control end power supply access end; 2. an on-off square wave controller; 3. a high-speed on-off controller; 31. a diode; 4. a high-speed varactor; 41. a primary stage; 42. secondary; 43. a magnetic ring body; 44. a primary enameled wire; 45. a secondary enameled wire; y, Y' ablation electrode; an output end of the V1 high-frequency high-voltage alternating current output circuit; the other output end of the V2 high-frequency high-voltage alternating current output circuit; x, X ', X ' '.
Detailed Description
The detailed description and technical content of the present invention are described below with reference to the drawings, which are, however, provided for reference and illustration only and are not intended to limit the present invention.
Referring to fig. 1, a high-frequency high-voltage circuit time division multiplexing control device according to an embodiment of the present invention includes a control end power supply access end 1, an on-off square wave controller 2, a high-speed on-off controller 3, and a high-speed varactor 4; the control end power supply access end 1 is used for accessing an isolated control end power supply (not shown in the figure), and the isolated control end power supply accessed to the control end power supply access end is a 12V direct current power supply in the invention, so as to be used as a control power supply (electric field) loaded on the high-speed on-off controller 3 and controlling the on or off of the high-speed on-off controller. The control end power supply access end 1 is electrically connected to the high-speed on-off controller 3 through the on-off square wave controller 2, wherein the on-off square wave controller 3 is a waveform signal control device which is widely applied in the field of electronic device control, so that the structure and the model of the control end power supply access end are not repeated, and the on-off square wave controller 2 controls the voltage on-off frequency of the control end power supply access end 1 loaded on the high-speed on-off controller 3 according to an on-off control signal (such as a square wave control signal); the high-speed on-off controller 3 is electrically connected with the primary of the high-speed variable reactor 4 and is used for controlling the on-off frequency of current flowing through the primary of the high-speed variable reactor 4 according to the voltage on-off frequency; in the invention, the on-off frequency of the on-off control signal is 50Hz to 1KHz, that is, the on-off square wave controller controls the primary current of the high-speed varactor to be conducted and disconnected 50 to 1000 times per second; the secondary of the high-speed variable reactor is electrically connected with the alternating current load circuit, is in a conducting state when the primary of the high-speed variable reactor is conducted with current, and generates reactance when the primary of the high-speed variable reactor is conducted without current.
More specifically, the high-speed varactor is similar to a transformer, the primary side of which is controlled to be in a short-circuit or open-circuit state, and the secondary side of which is connected in series in an ac circuit, as shown in fig. 2, the high-speed varactor 4 is composed of a magnetic ring body 43, a primary enameled wire 44 uniformly wound around the magnetic ring body 43, and a secondary enameled wire 45, wherein the primary enameled wire 44 wound around the magnetic ring body 43 forms a primary 41 of the high-speed varactor 4, and the secondary enameled wire 45 wound around the magnetic ring body 43 forms a secondary 42 of the high-speed varactor 4. The magnetic ring body 43 is made of 36X23X15 manganese zinc ferrite, the primary enamelled wire 44 has a diameter of 1.0mm and is uniformly wound on the magnetic ring body 43 for 15 circles, and the secondary enamelled wire 45 has a diameter of 0.8mm and is uniformly wound on the magnetic ring body 43 for 30 circles. When the primary 41 is not current conducting (open circuit), the secondary 42 generates a reactance, which generally varies with the frequency of the ac circuit and causes a phase change between the current and the voltage in the ac circuit, the reactance being given by: z=2pi fL, the reactance is known to be proportional to the frequency and inductance of the alternating current. In the present invention, the inductance of the secondary 42 of the high-speed varactor 4 is 2.5mH, according to the operating frequency of the radio frequency ablation device being generally 460KHz, when the primary 41 of the high-speed varactor 4 is open (no current passes through the primary), the secondary 42 of the high-speed varactor 4 is connected in series in an ac load circuit, which is equivalent to a 2.5mH inductance connected in series, and the reactance of the secondary 42 is z=2pi fl=2x3.14460000 x 2.5/1000=7.2kΩ, and the standard impedance of the radio frequency ablation device is generally 100-500 Ω, at this time, the reactance of the secondary 42 connected in series in the ac circuit is far greater than the standard impedance of the radio frequency ablation device, and according to ohm's law, the secondary 42 divides most of the voltage of the high-frequency and high-voltage ac current in the series circuit, and the load circuit only divides a small voltage; when the primary 41 of the high-speed varactor 4 is turned on (shorted), the reactance of the secondary 42 is very small, which is negligible compared to the standard impedance of the rf ablation device, so that the load circuit divides most of the voltage of the high-frequency high-voltage ac.
As shown in fig. 3, in the present invention, the high-speed on-off controller 3 is composed of two field effect transistors, specifically, two N-type MOS transistors are electrically connected to two ends of the primary 41 of the high-speed varactor 4, wherein the positive electrode of the power supply access end of the control end is electrically connected to the on-off square wave controller and then electrically connected to the gates G of the two N-type MOS transistors, the drain electrodes D of the two N-type MOS transistors are respectively electrically connected to one end and the other end of the primary 41 of the high-speed varactor 4, and the source electrodes S of the two N-type MOS transistors are electrically connected to the negative electrode GND of the power supply access end of the control end. According to the characteristics of large current and high speed of the N-type MOS tube, the on-off frequency (hundreds to thousands times per second) of the voltage (electric field) loaded between the grid electrode G and the source electrode S of the N-type MOS tube is controlled by utilizing the on-off control signal of the on-off square wave controller, so that the on-off frequency (that is, whether current flows out) of the current output of the drain electrode D of the N-type MOS tube is controlled, and the on-off of the current in the primary 41 of the high-speed variable reactor 4 is further controlled rapidly and stably. In addition, a diode 31 is electrically connected between the drain D and the source S of the two N-type MOS transistors, wherein the source S is electrically connected with the anode of the diode 31, and the drain D is electrically connected with the cathode of the diode 31. The diode 31 is used as a reverse (current) protection diode in the N-type MOS transistor, and particularly when a high-power N-type MOS transistor is selected, the reverse protection diode 31 is needed in the N-type MOS transistor, and the speed of the diode 31 is basically consistent with the on-off speed of the N-type MOS transistor. Specifically, under the control of the on-off control signal (e.g., square wave control signal) of the on-off square wave controller, a switching state of a loading voltage (electric field) and an unloading voltage is formed between the gate G and the source S of the N-type MOS transistor, so that the current output of the drain D is a switching state of current output and no current output. When a voltage is applied between the grid electrode G and the source electrode S of the N-type MOS tube to enable the drain electrode D to have current output, the primary 41 of the high-speed varactor 4 is in a conducting state, the secondary 42 of the high-speed varactor 4 is conducted by alternating current, under the action of electromagnetic induction, the alternating current flowing through the primary 41 is also the alternating current, as shown in fig. 4, is a schematic diagram that the alternating current flows clockwise in a loop formed by the two N-type MOS tubes and the primary 41, the current flows out from the negative electrode GND of the power supply inlet end of the control end, flows to the primary 41 of the high-speed varactor 4 through the diode 31 of the upper N-type MOS tube, flows back to the negative electrode GND of the power supply inlet end of the control end after flowing to the lower N-type MOS tube, and forms a closed loop, and the voltage drop between the N-type MOS tube and the diode 31 is small and can be ignored, so that the current is equivalent to the short circuit of the primary 41 of the high-speed varactor 4; as shown in fig. 5, an ac current flows anticlockwise in a loop formed by two N-type MOS transistors and the primary 41, the current flows out from the negative electrode GND of the power supply access terminal of the control terminal, passes through the diode 31 of the N-type MOS transistor below to the primary 41 of the high-speed varactor 4, then flows back to the negative electrode GND of the power supply access terminal of the control terminal after passing through the N-type MOS transistor above, and forms a closed loop, and the voltage drop between the N-type MOS transistor and the diode 31 is negligible because of small voltage drop, so that the current is equivalent to a short circuit of the primary 41 of the high-speed varactor 4.
The invention also provides a multi-electrode radio frequency ablation system electrically connected to a high-frequency high-voltage alternating current output circuit (not shown), the multi-electrode radio frequency ablation system comprising: two isolated control end power supplies (not shown), at least two groups of high-frequency high-voltage circuit time division multiplexing control devices and at least two groups of ablation electrodes; as shown in fig. 6 and 7, which are two embodiments of the multi-electrode rf ablation system of the invention, fig. 6 shows a multi-electrode rf ablation system having two sets of ablation electrodes and fig. 7 shows a multi-electrode rf ablation system having three sets of ablation electrodes. Each group of high-frequency high-voltage circuit time-sharing multiplexing control device comprises two high-frequency high-voltage circuit time-sharing multiplexing control devices; each set of ablation electrodes includes two ablation electrodes Y, Y'; the two isolated control end power supplies are respectively and correspondingly connected to the control end power supply access ends of the two high-frequency high-voltage circuit time-sharing multiplexing control devices of each group of high-frequency high-voltage circuit time-sharing multiplexing control devices, in the invention, no matter how groups of high-frequency high-voltage circuit time-sharing multiplexing control devices are, only two isolated control end power supplies are needed, as shown in fig. 6 and 7, GND1 and GND2 are respectively used for representing the cathodes of the two isolated control end power supplies; an output end V1 of the high-frequency high-voltage alternating current output circuit is electrically connected to one end of the secondary 42 of one high-frequency high-voltage circuit time division multiplexing control device 4 of each group of high-frequency high-voltage circuit time division multiplexing control devices, and another output end V2 of the high-frequency high-voltage alternating current output circuit is electrically connected to one end of the secondary 42 of the other high-frequency high-voltage circuit time division multiplexing control device 4 of each group of high-frequency high-voltage circuit time division multiplexing control devices; each group of ablation electrodes (two ablation electrodes Y, Y') is correspondingly connected to the other end of the secondary 42 of the high-speed varactor 4 of the two high-frequency high-voltage circuit time division multiplexing control devices of each group of high-frequency high-voltage circuit time division multiplexing control devices.
As shown in fig. 8, a waveform diagram of on-off control signals of each on-off square wave controller in a multi-electrode radio frequency ablation system with two groups of ablation electrodes is shown, wherein the on-off control signals X are on-off control signals for controlling a first group of high-frequency high-voltage circuit time-division multiplexing control device, and the on-off control signals X' are on-off control signals for controlling a second group of high-frequency high-voltage circuit time-division multiplexing control device; fig. 9 is a waveform diagram of on-off control signals of each on-off square wave controller in a multi-electrode radio frequency ablation system with three groups of ablation electrodes, wherein the on-off control signals X are on-off control signals for controlling a first group of high-frequency high-voltage circuit time division multiplexing control devices, the on-off control signals X' are on-off control signals for controlling a second group of high-frequency high-voltage circuit time division multiplexing control devices, the on-off control signals X″ are on-off control signals for controlling a third group of high-frequency high-voltage circuit time division multiplexing control devices, and the primary of a high-speed varactor is in a short circuit state when in a waveform, which is equivalent to that an output circuit is conducted with the ablation electrodes; the primary of the high-speed variable reactor is in an open circuit state when in low level, which is equivalent to the open circuit of the output circuit and the ablation electrode. The square wave phase difference of the on-off control signals of the on-off square wave controllers of the high-frequency high-voltage circuit time-sharing multiplexing control devices of all groups is 360 degrees/the number of groups of the high-frequency high-voltage circuit time-sharing multiplexing control devices; the duty ratio of square wave waveform of on-off control signals of on-off square wave controllers of the high frequency and high voltage circuit time division multiplexing control devices of all groups is 100% of the number of groups of on-off control signals of the 1/high frequency and high voltage circuit time division multiplexing control devices, namely, the on-off control signals X and X 'of two groups of ablation electrodes are 2 square waves which are 180 degrees different, the duty ratio of the waveforms is 50%, the on-off control signals X, X' and X″ of three groups of ablation electrodes are 3 square waves which are 120 degrees different, the duty ratio of the waveforms is 33.33%, and the like, the phase difference of the on-off control signals of N groups of ablation electrodes is (360/N) degrees, and the duty ratio of the waveforms is 1/N100%. Therefore, the stable operation of time-sharing multiplexing of the plurality of groups of ablation electrodes of the multi-electrode radio frequency ablation system can be ensured.
The invention carries out time-sharing multiplexing on the output of high-frequency high-voltage alternating current through the high-frequency high-voltage circuit time-sharing multiplexing control device so as to time-share the output high-frequency high-voltage alternating current on each group of electrodes, the time-sharing time interval is extremely small and is 50 to more than 1000 times per second, only one group of electrodes works in each time period, the multiple groups of electrodes which are time-sharing multiplexed uniformly work on the treatment tissue, the current density output by each group of electrodes is not affected, the ablation impedance is not affected, and the time-sharing multiplexing control device is macroscopically and effectively equivalent to the multiple groups of electrodes to time-share the same high-frequency high-voltage alternating current on human tissues. According to the method, the ablation effects of the plurality of groups of electrodes respectively and independently acting on the tissues can be accumulated, and finally, the ablation effects of the plurality of groups of electrodes simultaneously acting on the tissues are achieved.
The foregoing description of the preferred embodiments of the present invention is not intended to limit the scope of the invention, and other equivalent variations using the inventive concepts are intended to fall within the scope of the invention.
Claims (8)
1. A high frequency high voltage circuit time division multiplexing control device, comprising: the control end power supply access end, the on-off square wave controller, the high-speed on-off controller and the high-speed variable reactor; the control end power supply access end is electrically connected to the high-speed on-off controller through the on-off square wave controller, and the on-off square wave controller controls the voltage on-off frequency of the control end power supply access end loaded on the high-speed on-off controller according to an on-off control signal; the high-speed on-off controller is composed of two N-type MOS tubes electrically connected with two ends of a primary of the high-speed varactor, wherein the positive electrode of the power supply access end of the control end is electrically connected with the on-off square wave controller and then is electrically connected with the grid electrodes of the two N-type MOS tubes, the drain electrodes of the two N-type MOS tubes are respectively and electrically connected with one end and the other end of the primary of the high-speed varactor, and the source electrodes of the two N-type MOS tubes are electrically connected with the negative electrode of the power supply access end of the control end so as to control the on-off frequency of current flowing through the primary of the high-speed varactor according to the on-off frequency of voltage; one end of a secondary of the high-speed variable reactor is electrically connected with an output end of a high-frequency high-voltage alternating current output circuit, the other end of the secondary of the high-speed variable reactor is connected with an ablation electrode, when a primary of the high-speed variable reactor is conducted with current, conduction is realized between the output end of the high-frequency high-voltage alternating current output circuit of the secondary and the ablation electrode, and when the primary of the high-speed variable reactor is conducted without current, reactance is generated between the output end of the high-frequency high-voltage alternating current output circuit of the secondary and the ablation electrode; each group of high-frequency high-voltage circuit time division multiplexing control device comprises two high-frequency high-voltage circuit time division multiplexing control devices, the square wave phase difference of on-off control signals of on-off square wave controllers of the high-frequency high-voltage circuit time division multiplexing control devices is 360 degrees/the number of groups of the high-frequency high-voltage circuit time division multiplexing control devices, and the square wave duty ratio of the on-off control signals of the on-off square wave controllers of the high-frequency high-voltage circuit time division multiplexing control devices is 1/100% of the number of groups of the high-frequency high-voltage circuit time division multiplexing control devices so as to realize time division multiplexing of at least two groups of ablation electrodes.
2. The high-frequency high-voltage circuit time division multiplexing control device according to claim 1, wherein the high-speed varactor is composed of a magnetic ring body, primary enameled wires and secondary enameled wires which are uniformly wound on the magnetic ring body, wherein the primary enameled wires wound on the magnetic ring body form a primary of the high-speed varactor, and the secondary enameled wires wound on the magnetic ring body form a secondary of the high-speed varactor.
3. The high-frequency high-voltage circuit time division multiplexing control device according to claim 2, wherein the magnetic ring body is made of 36X23X15 manganese zinc ferrite, the primary enameled wire is 1.0mm in diameter and uniformly wound on the magnetic ring body for 15 circles, and the secondary enameled wire is 0.8mm in diameter and uniformly wound on the magnetic ring body for 30 circles.
4. The device according to claim 1, wherein a diode is electrically connected between the drain and the source of the two N-type MOS transistors, wherein the source is electrically connected to the anode of the diode, and the drain is electrically connected to the cathode of the diode.
5. The high-frequency high-voltage circuit time division multiplexing control device according to claim 1, wherein the on-off frequency of the on-off control signal is 50Hz to 1KHz.
6. The high-frequency high-voltage circuit time division multiplexing control device according to claim 1, wherein an inductance of a secondary of the high-speed varactor is 2.5mH.
7. A multi-electrode rf ablation system electrically connected to a high frequency high voltage ac output circuit, the system comprising: two isolated control terminal power supplies, at least two groups of high-frequency high-voltage circuit time division multiplexing control devices according to any one of claims 1 to 6 and at least two groups of ablation electrodes; wherein each set of said ablation electrodes comprises two ablation electrodes; the two isolation control end power supplies are respectively and correspondingly connected to the control end power supply access ends of the two high-frequency high-voltage circuit time-sharing multiplexing control devices of each group of the high-frequency high-voltage circuit time-sharing multiplexing control devices; an output end of the high-frequency high-voltage alternating current output circuit is electrically connected with one end of a secondary side of a high-speed variable reactor of one high-frequency high-voltage circuit time division multiplexing control device in each group of the high-frequency high-voltage circuit time division multiplexing control devices, and another output end of the high-frequency high-voltage alternating current output circuit is electrically connected with one end of a secondary side of a high-speed variable reactor of another high-frequency high-voltage circuit time division multiplexing control device in each group of the high-frequency high-voltage circuit time division multiplexing control devices; each group of the ablation electrodes is correspondingly connected to the other end of the secondary side of the high-speed variable reactor of the two high-frequency high-voltage circuit time division multiplexing control devices of each group of the high-frequency high-voltage circuit time division multiplexing control devices.
8. The multi-electrode rf ablation system according to claim 7, wherein the isolated control side power source is a 12V dc power source.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910490444.0A CN110123445B (en) | 2019-06-06 | 2019-06-06 | High-frequency high-voltage circuit time-sharing multiplexing control device and multi-electrode radio frequency ablation system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910490444.0A CN110123445B (en) | 2019-06-06 | 2019-06-06 | High-frequency high-voltage circuit time-sharing multiplexing control device and multi-electrode radio frequency ablation system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110123445A CN110123445A (en) | 2019-08-16 |
| CN110123445B true CN110123445B (en) | 2024-01-12 |
Family
ID=67580490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910490444.0A Active CN110123445B (en) | 2019-06-06 | 2019-06-06 | High-frequency high-voltage circuit time-sharing multiplexing control device and multi-electrode radio frequency ablation system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110123445B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115054362A (en) * | 2022-07-28 | 2022-09-16 | 杭州德诺电生理医疗科技有限公司 | Ablation system |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2374897A (en) * | 1996-04-30 | 1997-11-19 | Cathrx Ltd | A system for simultaneous unipolar multi-electrode ablation |
| JP2000005191A (en) * | 1998-06-25 | 2000-01-11 | Olympus Optical Co Ltd | High-frequency therapeutic device |
| JP2000231998A (en) * | 1999-02-10 | 2000-08-22 | Toko Inc | Power source circuit for lighting discharge tube |
| CN1582861A (en) * | 2004-06-09 | 2005-02-23 | 南京恒埔伟业科技股份有限公司 | Radio multi-electrode time divided thermotherapeutical apparatus |
| CN102332824A (en) * | 2011-09-23 | 2012-01-25 | 东南大学 | Time sharing multiplex control method for single-inductance double-output switching power supply and circuit thereof |
| CN103929066A (en) * | 2014-04-30 | 2014-07-16 | 杨飏 | Wide-range single-inductor multiple-output converter |
| KR20160038126A (en) * | 2014-09-29 | 2016-04-07 | 전자부품연구원 | Cautery electrode assembly and electrical cautery apparatus having the same |
| CN105554965A (en) * | 2016-02-24 | 2016-05-04 | 西南交通大学 | Topology of bus current complementary time division multiplexing constant current output LED driver and control method thereof |
| CN206602467U (en) * | 2017-03-09 | 2017-10-31 | 北京航天长征飞行器研究所 | One kind uses monolithic processor controlled off-line type high voltage isolated power supply device |
-
2019
- 2019-06-06 CN CN201910490444.0A patent/CN110123445B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2374897A (en) * | 1996-04-30 | 1997-11-19 | Cathrx Ltd | A system for simultaneous unipolar multi-electrode ablation |
| JP2000005191A (en) * | 1998-06-25 | 2000-01-11 | Olympus Optical Co Ltd | High-frequency therapeutic device |
| JP2000231998A (en) * | 1999-02-10 | 2000-08-22 | Toko Inc | Power source circuit for lighting discharge tube |
| CN1582861A (en) * | 2004-06-09 | 2005-02-23 | 南京恒埔伟业科技股份有限公司 | Radio multi-electrode time divided thermotherapeutical apparatus |
| CN102332824A (en) * | 2011-09-23 | 2012-01-25 | 东南大学 | Time sharing multiplex control method for single-inductance double-output switching power supply and circuit thereof |
| CN103929066A (en) * | 2014-04-30 | 2014-07-16 | 杨飏 | Wide-range single-inductor multiple-output converter |
| KR20160038126A (en) * | 2014-09-29 | 2016-04-07 | 전자부품연구원 | Cautery electrode assembly and electrical cautery apparatus having the same |
| CN105554965A (en) * | 2016-02-24 | 2016-05-04 | 西南交通大学 | Topology of bus current complementary time division multiplexing constant current output LED driver and control method thereof |
| CN206602467U (en) * | 2017-03-09 | 2017-10-31 | 北京航天长征飞行器研究所 | One kind uses monolithic processor controlled off-line type high voltage isolated power supply device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110123445A (en) | 2019-08-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3111873B1 (en) | Electrosurgical generator for minimizing neuromuscular stimulation | |
| EP2777577B1 (en) | Crest-factor control of phase-shifted inverter | |
| US8945115B2 (en) | System and method for power supply noise reduction | |
| US8617154B2 (en) | Current-fed push-pull converter with passive voltage clamp | |
| CN101998843B (en) | Electrocautery method and apparatus | |
| US20160287311A1 (en) | Interdigitation of waveforms for dual-output electrosurgical generators | |
| CN107334523B (en) | Electrosurgical generator and electrosurgical system | |
| JP2000516516A (en) | Improved electrosurgical generator | |
| EP2169826B1 (en) | Circuit for radiofrequency devices applicable to living tissues and device containing same | |
| CN104052269A (en) | Constant power inverter with crest factor control | |
| CN108095820A (en) | A kind of nano-knife tumour ablation control device and its control method | |
| JP3636511B2 (en) | Electrosurgical equipment | |
| CN110123445B (en) | High-frequency high-voltage circuit time-sharing multiplexing control device and multi-electrode radio frequency ablation system | |
| CN109999340A (en) | A kind of loaded self-adaptive nanosecond pulse generation device | |
| CN115177357A (en) | Bimodal tissue ablation device | |
| CN113768612B (en) | High voltage transmitting circuit for catheter and ablation instrument | |
| CN210494221U (en) | High-frequency high-voltage circuit time-sharing multiplexing control device and multi-electrode radio frequency ablation system | |
| CN210750900U (en) | Load self-adaptive nanosecond pulse generation device | |
| Ivanov et al. | RF Output Signal Commutation in Multi-channel Electrosurgical Unit | |
| US20170354455A1 (en) | Variable active snubber circuit to induce zero-voltage-switching in a current-fed power converter | |
| Folprecht et al. | Experimental High-voltage AC Generators for Cardiological Purposes | |
| KR20220136177A (en) | Electromedical power generator | |
| Shrotriya et al. | Development of solid state modulating anode power supply for 1 MW Klystron system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |