CN202390427U - Thermostatic rotary type blood bacteria culturing device with 50 bottle places - Google Patents
Thermostatic rotary type blood bacteria culturing device with 50 bottle places Download PDFInfo
- Publication number
- CN202390427U CN202390427U CN 201120122690 CN201120122690U CN202390427U CN 202390427 U CN202390427 U CN 202390427U CN 201120122690 CN201120122690 CN 201120122690 CN 201120122690 U CN201120122690 U CN 201120122690U CN 202390427 U CN202390427 U CN 202390427U
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- China
- Prior art keywords
- constant temperature
- blood
- bottles
- control system
- culturing device
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/10—Rotating vessel
- C12M27/12—Roller bottles; Roller tubes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/08—Flask, bottle or test tube
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/50—Means for positioning or orientating the apparatus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
Abstract
The utility model relates to a thermostatic rotary type blood bacteria culturing device with 50 bottle places, wherein the blood bacteria culturing device can be used on a Labstar 50 type full-automatic blood culture instrument. The rotary type blood bacteria culturing device solves problems that blood sample is manually cultured for a long time and easy to be polluted by using constant temperature, rotation and vibration methods. The blood bacteria culturing device comprises a closed shell, a controlled door, a culture bottle turntable with 50 bottle places, a motor, a mechanical control system, a motor controller, a thermostatic system, a culture bottle position sensor and a bacteria growth detector; the motor controller, the thermostatic system and the culture bottle position sensor are connected with the mechanical control system; and the bacteria growth detector is connected with a detection system.
Description
Technical field
The utility model belongs to the medical instruments and equipment field, is specifically related to the rotary blood incubator of constant temperature of full-automatic hemoculture appearance.
Background technology
Because the progress of medical skill; Various diagnoses and treatment means grow with each passing day; Like organ transplantation; Being widely used of antitumor drug, Broad spectrum antibiotics, immunosuppressor, various intervention property inspection treatments, intravenous hyperalimentation and other catheter retaining etc. all are creating conditions of microbemia, septicemia.Microbemia and septicemia disease time are rapid, and mortality ratio is higher.
The incidence of blood infection obviously increases over nearly 20 years, and is present 13% by rising to 6% of the end of the year 70 according to authoritative statistics, and this does not comprise that also quite a few is by microbemia and septicemia that anaerobic infection caused.Because microbemia and septicemia are the diseases that seriously jeopardizes patient's life clinically; Mortality ratio is up to 29%; And the blood microbial culture is the important evidence of establishing microbemia and septicemia diagnosis; For the patient of severe infections property disease, can effectively cure, be decided by microbial culture report promptly and accurately to a great extent.Traditional-handwork is cultivated detection method and is relied on manual static to cultivate; The microbial growth situation detects by an unaided eye; Shortcoming such as have that microorganism growth is poor, incubation time long (7 days even longer), positive rate detect low, poor accuracy; Seriously delay clinical smelting and treat, far can not adapt to the needs of modern clinical treatment.
The core technology of full-automatic hemoculture appearance is that fast culture and the highly sensitive to bacterium detects accurately, has only U.S. company BD and French Mei Liai company to have this series products at present in the world.I am made up of full-automatic cultivation appearance and culturing bottle by the Labstar50 automatic blood bacteria culture instrument of company's development; The advantage of integrated U.S. B-D and French Biomerieux SA two product; Widely applied up-to-date scientific and technological achievement simultaneously; Blood preparation is inoculated in the nutrient solution of culturing bottle, concussion is to quicken microbial culture continuously in Constant Temperature Incubators for Blood culture bottle, and bacterium in reproductive process, causes the fluorescence intensity of fluorescent indicator in the culturing bottle to change and colourity changes; Detection system promptly and accurately detects faint fluorescence and colourity variation; Record also shows the bacterial growth situation, draws growth curve, and accurate judgement sample male stagnation point is also made report.It is blank that the full-automatic hemoculture appearance of LABSTAR50 type has been filled up China; Broken foreign monopolization; The full-automation that realizes the blood microbial culture for China's middle and small hospital has brought hope; This equipment is made up of instrument part and supporting culturing bottle, and the instrument part comprises constant temperature blood incubator and detection system two parts again.Constant temperature blood incubator is an enclosed construction, 35 ° of left and right sides temperature of inner maintenance, and to help bacterial growth, the culturing bottle that blood preparation is housed is placed on the rotating disk wherein, utilizes the method for rotational oscillation, quickens bacterial growth.
The utility model content
In order to realize full automatic blood microbial culture and detection; The utility model is as an integral part of full-automatic hemoculture appearance; Utilize the method for constant temperature and rotation concussion, realize the quick growth of blood bacterium, create conditions for the detection system highly sensitive detects accurately simultaneously.
It is following that the utility model solves the technical scheme that its technical problem adopted: the rotary blood incubator of a kind of 50 bottles of position constant temperature; It comprises closed shell and controlled switch door; On the said door Mgs is housed, said Mgs is controlled by computerized control system.Wherein, the blood incubator also comprises 50 bottles of position culturing bottle rotating disks and the Machinery Control System that contains stepper-motor, step-down gear, connecting rod; Said rotating disk is provided with the hole of placing 50 culturing bottles; It outwards is three layers of circle by center of turntable and arranges; Said stepper-motor drives rotating disk with the running of PM 15 Lap Time degree through mechanical system, receives computerized control system its startup of control simultaneously and stops, so that carried out one time signal detection in per 10 minutes.
Preferably, said blood incubator also comprises constant temperature system, and said constant temperature system contains TP, fan, hot-plate, and said TP is connected with monitoring device, and controlled temperature is at 35 ° ± 1.5 °.
Preferably, said blood incubator also comprises electric machine controller, and said electric machine controller is installed in the motor, and is connected with monitoring device.
Preferably, said blood incubator also comprises the position transducer that is used to detect the culturing bottle position, and said position transducer is connected with monitoring device.
Preferably; Said blood incubator also comprises three groups of bacterial growth detectors of being made up of spectral filter, LED, PD; Every group contains 1 spectral filter, 4 LED and 1 PD; It is placed in the rotating disk back side, and with corresponding with three circle culturing bottles detection hole sites, said bacterial growth detector is connected with detection system.
This utility model is applicable to following purposes as the part of the full-automatic hemoculture appearance of Labstar50 type of my company research and development:
1) this product is applicable to cultivation and the detection of bacterium in clinical blood and other aseptic cavity liquid (as: hydrothorax, cerebrospinal fluid, bile, the ascites etc.) sample, for septicemia, bacteremic clinical diagnosis provide foundation.
2) and be applicable to the aseptic rapid detection of medicine, food, agricultural byproducts and other Industrial products.
3) can also implement fast selective to some special bacterial classifications cultivates.
Compared with prior art, the beneficial effect of the utility model is:
1. detecting the result with the manual static cultivation needed compare in 7 days, and present technique 90% positive sample can be to be detected in 12 (24) hours, can detect 99% positive sample (some sample is the fastest only to need 2-4 hour) in 36 hours.Shortened patient's treatment time greatly.
2. take the computerized control system closed constant temperature culture of control automatically, avoid polluting, accuracy, safety high (almost non-false positive, false negative).
3. need not manual operations, easy to operate and safe.
Description of drawings
Fig. 1 is the structured flowchart of the full-automatic hemoculture appearance of Labstar50 type, and wherein, dotted portion is the structural representation according to the rotary blood incubator of the constant temperature of the utility model.
Embodiment
Below in conjunction with accompanying drawing and embodiment the utility model is further specified, but not as the qualification to the utility model.
See also Fig. 1, Fig. 1 is the embodiment of the automatic hemoculture appearance detection system of the utility model.
It is following that the utility model solves the technical scheme that its technical problem adopted: a kind of constant temperature blood incubator of automatic hemoculture appearance, and it comprises closed shell and autocontrol switch door, on the door Mgs is housed, the switch of door is controlled by computerized control system; Also comprise 50 bottles of position culturing bottle rotating disks and Machinery Control System (containing stepper-motor, step-down gear, connecting rod, rotating disk etc.) thereof, rotating disk has the hole that can place 50 culturing bottles, outwards is three layers of circle by center of turntable and arranges.Under computerized control system control, stepper-motor passes through mechanical system and drives rotating disk with the running of PM 15 Lap Time degree, and is every at a distance from 10 minutes, and stepper-motor carries out stepped start-stop system and starts and stop to move, so that carry out one group of signal detection.
Also comprise constant temperature system, contain TP, fan, hot-plate, TP is connected with monitoring device, and controlled temperature is at 35 ° ± 1.5 °.
Also comprise electric machine controller, said electric machine controller is installed in the motor, and is connected with monitoring device.
Also comprise position transducer, be used to detect the culturing bottle position, said position transducer is connected with monitoring device.
Also comprise the bacterial growth detector of forming by spectral filter, LED, PD; Totally three groups, every group contains 1 spectral filter, 4 LED and 1 PD, is placed in the rotating disk back side; Corresponding with three circle culturing bottles detection hole sites, said bacterial growth detector is connected with detection system.
Above-described embodiment, the utility model embodiment a kind of more preferably just, common variation that those skilled in the art carries out in the utility model technical scheme scope and replacement all should be included in the protection domain of the utility model.
Claims (4)
1. rotary blood incubator of 50 bottles of position constant temperature, it comprises closed shell and controlled switch door, on the said controlled switch door Mgs is housed, said Mgs is controlled by computerized control system; It is characterized in that said blood incubator also comprises 50 bottles of position culturing bottle rotating disks and the Machinery Control System that comprises stepper-motor, step-down gear, connecting rod; Wherein, Said rotating disk is provided with the hole of placing 50 culturing bottles, and said hole outwards is three layers of circle by center of turntable arranges, and said stepper-motor drives rotating disk through mechanical system and turns round with PM 15 Lap Time degree; Said stepper-motor inner electric machine unit; It is controlled by computerized control system, carries out stepped start-stop system in per 10 minutes and starts and stop, and is used for signal detection.
2. the rotary blood incubator of constant temperature according to claim 1; It is characterized in that also comprise constant temperature system, said constant temperature system comprises TP, fan, hot-plate; Said TP is connected with monitoring device, and controlled temperature is at 35 ° ± 1.5 °.
3. the rotary blood incubator of constant temperature according to claim 1 is characterized in that also comprise the position transducer that is used to detect the culturing bottle position, said position transducer is connected with monitoring device.
4. the rotary blood incubator of constant temperature according to claim 1; It is characterized in that; Also comprise three groups of bacterial growth detectors of being made up of spectral filter, LED, PD, every group contains 1 spectral filter, 4 LED and 1 PD, and it is placed in the rotating disk back side; With corresponding with three circle culturing bottles detection hole sites, said bacterial growth detector is connected with detection system.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120122690 CN202390427U (en) | 2011-04-25 | 2011-04-25 | Thermostatic rotary type blood bacteria culturing device with 50 bottle places |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120122690 CN202390427U (en) | 2011-04-25 | 2011-04-25 | Thermostatic rotary type blood bacteria culturing device with 50 bottle places |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202390427U true CN202390427U (en) | 2012-08-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201120122690 Expired - Lifetime CN202390427U (en) | 2011-04-25 | 2011-04-25 | Thermostatic rotary type blood bacteria culturing device with 50 bottle places |
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| CN (1) | CN202390427U (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102796652A (en) * | 2012-09-05 | 2012-11-28 | 曲阜裕隆生物科技有限公司 | Constant temperature shaking table body |
| CN102807951A (en) * | 2012-09-05 | 2012-12-05 | 曲阜裕隆生物科技有限公司 | Constant-temperature shaking table unit |
| CN103409316A (en) * | 2013-08-22 | 2013-11-27 | 山东鑫科生物科技股份有限公司 | Constant temperature control system for blood bacterial culture instrument |
| CN103555562A (en) * | 2013-11-01 | 2014-02-05 | 山东鑫科生物科技股份有限公司 | Blood culture instrument |
| CN104390827A (en) * | 2014-12-15 | 2015-03-04 | 王东生 | Blood incubator |
| CN109306319A (en) * | 2018-11-15 | 2019-02-05 | 山东省医疗器械产品质量检验中心 | The fast check system of medical device sterile and its application method |
| CN113355218A (en) * | 2020-03-05 | 2021-09-07 | 房本院 | Full-automatic blood bacteria culture appearance of screw propulsion formula for clinical laboratory of hospital |
-
2011
- 2011-04-25 CN CN 201120122690 patent/CN202390427U/en not_active Expired - Lifetime
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102796652A (en) * | 2012-09-05 | 2012-11-28 | 曲阜裕隆生物科技有限公司 | Constant temperature shaking table body |
| CN102807951A (en) * | 2012-09-05 | 2012-12-05 | 曲阜裕隆生物科技有限公司 | Constant-temperature shaking table unit |
| CN102807951B (en) * | 2012-09-05 | 2015-09-02 | 曲阜裕隆生物科技有限公司 | A kind of constant-temperature table unit |
| CN103409316A (en) * | 2013-08-22 | 2013-11-27 | 山东鑫科生物科技股份有限公司 | Constant temperature control system for blood bacterial culture instrument |
| CN103555562A (en) * | 2013-11-01 | 2014-02-05 | 山东鑫科生物科技股份有限公司 | Blood culture instrument |
| CN104390827A (en) * | 2014-12-15 | 2015-03-04 | 王东生 | Blood incubator |
| CN109306319A (en) * | 2018-11-15 | 2019-02-05 | 山东省医疗器械产品质量检验中心 | The fast check system of medical device sterile and its application method |
| CN113355218A (en) * | 2020-03-05 | 2021-09-07 | 房本院 | Full-automatic blood bacteria culture appearance of screw propulsion formula for clinical laboratory of hospital |
| CN113355218B (en) * | 2020-03-05 | 2022-07-12 | 上海揽微赛尔生物科技有限公司 | Full-automatic blood bacteria culture appearance of screw propulsion formula for clinical laboratory of hospital |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20120822 |