CN202322815U - Lifting device and bioreactor - Google Patents

Lifting device and bioreactor Download PDF

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Publication number
CN202322815U
CN202322815U CN 201120490751 CN201120490751U CN202322815U CN 202322815 U CN202322815 U CN 202322815U CN 201120490751 CN201120490751 CN 201120490751 CN 201120490751 U CN201120490751 U CN 201120490751U CN 202322815 U CN202322815 U CN 202322815U
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CN
China
Prior art keywords
bio
reactor
screw mandrel
guidepost
fixedly connected
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN 201120490751
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Chinese (zh)
Inventor
王建超
高博学
陈文庆
张韧
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Merck Millipore Beijing Skywing Co ltd
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Beijing Skywing Technology Co Ltd
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Priority to CN 201120490751 priority Critical patent/CN202322815U/en
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Publication of CN202322815U publication Critical patent/CN202322815U/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/38Caps; Covers; Plugs; Pouring means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/48Holding appliances; Racks; Supports
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The utility model provides a lifting device and a bioreactor, which are used for solving the problems that the operation is fussy, large labor force is consumed, the culture environment in the bioreactor is easily polluted and the sterile performance of the bioreactor is difficult to ensure when the tank cover of the bioreactor is lifted in the prior art. The lifting device comprises an upright post, a guiding post, a screw rod, a moving block, a lifting arm and a motor controller, wherein the upright post is provided with a base; the guiding post is axially and fixedly connected with the upright post; the screw rod is arranged in parallel to the guiding post, a screw sleeve is sleeved on the screw rod, and the screw rod is in transmission connection with a driving shaft of a motor; the moving block is glidingly sleeved on the guiding post and fixedly connected with the screw sleeve; one end of the lifting arm is fixedly connected with the moving block, and the other end of the lifting arm is provided with a connecting part; and the motor controller is connected with the motor. The operation of lifting the tank cover of the bioreactor by using the lifting device is easy and safe, a little labor force is consumed, the probability that an operator is in contact with the bioreactor is reduced, the probability that the culture environment in the bioreactor is polluted is reduced, and the sterile performance of the bioreactor can be ensured.

Description

A kind of lifting device and bio-reactor
Technical field
The utility model relates to the bioreactor technology field, particularly a kind of lifting device and bio-reactor.
Background technology
The prior biological reactor drum has on a small scale bio-reactor such as 5L, 7.5L, 10L bio-reactor and extensive bio-reactor such as 100L, 500L, 1000L, 4000L bio-reactor.
For the small-scale bio-reactor, its cover weight and volume are all little, can manual work move usually, but manual work are easy to make the biological respinse environment to be polluted when moving the bio-reactor cover, are difficult to guarantee the degree of cleaning of biological respinse.
For extensive bio-reactor, its cover weight and volume are all bigger than normal, are not suitable for manual work and move.In the prior art, adopt hoist crane to realize the carrying and the installation of extensive bio-reactor cover usually at the bio-reactor production plant.Hoist crane refers to have bottle gouard moved by hands and electricblock form by the light little weight handling equipment that drive unit, transmission mechanism, drift stop and flexible volume are put or clamping device drive load-engaging device goes up and down that is contained on the public suspension bracket.Each when using bio-reactor, all will with the bio-reactor tank body lift to the lifting cucurbit under, and need two people operation simultaneously; Wherein a people spurs the lifting cucurbit, another people holds up cover on the steady bio-reactor, could guarantee machine safety and personnel safety, not only complex operation like this; Labor intensive; And operator also can touch the bio-reactor cover, and the bioreactor culture environment is polluted, and are difficult to guarantee the aseptic performance of bio-reactor.
It is thus clear that, prior art when mentioning or put down the bio-reactor cover, complex operation not only, labor intensive, and the culture environment in the bio-reactor is polluted is difficult to guarantee the bio-reactor aseptic performance.
The utility model content
The utility model embodiment provides a kind of lifting device and bio-reactor; In order to solve prior art when the handling bio-reactor cover, complex operation not only, labor intensive; And pollute the culture environment in the bio-reactor easily, be difficult to guarantee the problem of bio-reactor aseptic performance.
The utility model embodiment provides a kind of lifting device, comprising:
Column is provided with the base that is used for vertically fixing said column;
Guidepost is connected with said column axial restraint;
Screw mandrel laterally arranges with said guidepost, is arranged with swivel nut, and is in transmission connection with the drive shaft of said motor;
Movable block is sheathed on the said guidepost through slip cap slidably, and is fixedly connected with said swivel nut;
Lifting arm, an end is fixedly connected with said movable block, and the other end is provided with and is used for the connection section that is connected with the bio-reactor cover;
Be used to control the electric machine controller that the drive shaft of said motor clockwise rotates or rotates counterclockwise, be connected with said motor.
Wherein, preferably, said slip cap is arranged between said movable block and the said guidepost, and is fixedly connected with said movable block.
Wherein, preferably, described lifting device also comprises:
Be used to the screw rodb base that prevents that said screw mandrel from rocking, be arranged at the top of said screw mandrel;
Top board is fixedly connected with said screw rodb base with the top of said guidepost.
Wherein, preferably, said connection section is specially interface arrangment or hook pull-up structure.
Wherein, preferably, said screw mandrel is a T type screw mandrel, and said swivel nut is a T type swivel nut.
The utility model embodiment provides a kind of bio-reactor, comprising:
Lifting device comprises:
Column is provided with the base that is used for vertically fixing said column;
Guidepost is connected with said column axial restraint;
Screw mandrel laterally arranges with said guidepost, is arranged with swivel nut, and is in transmission connection with the drive shaft of said motor;
Movable block is sheathed on the said guidepost through sliding shoe slidably, and is fixedly connected with said swivel nut;
Lifting arm, an end is fixedly connected with said movable block, and the other end is provided with the connection section that is connected with the bio-reactor cover;
Be used to control the electric machine controller that the drive shaft of said motor clockwise rotates or rotates counterclockwise, be connected with said motor.
Wherein, preferably, said slip cap is arranged between said movable block and the said guidepost, and is fixedly connected with said movable block.
Wherein, preferably, said lifting device also comprises:
Be used to the screw rodb base that prevents that said screw mandrel from rocking, be arranged at the top of said screw mandrel;
Top board is fixedly connected with said screw rodb base with the top of said guidepost.
Wherein, preferably, said connection section is specially interface arrangment or hook pull-up structure.
Wherein, preferably, said screw mandrel is a T type screw mandrel, and said swivel nut is a T type swivel nut.
The lifting device that the utility model embodiment provides; Only need the user to utilize the drive shaft of motor controller controls motor to clockwise rotate or rotate counterclockwise; The electric motor driving lead screw transmission mechanism drives lifting arm and rises or descend, thereby realizes that the bio-reactor cover that is fixedly connected with lifting arm rises or descends; Compared with prior art; Utilize simple to operate, the safety of this lifting device handling bio-reactor cover; Labor intensive is few; And reduced the chance that operator contact bio-reactor, and reduced the probability that the culture environment in the bio-reactor is polluted, can guarantee the bio-reactor aseptic performance.
Description of drawings
Fig. 1 is the structural representation of a kind of lifting device among the utility model embodiment;
Fig. 2 is the structural representation of another kind of lifting device among the utility model embodiment;
Fig. 3 is the structural representation of a kind of bio-reactor among the utility model embodiment.
Embodiment
For technical problem, technical scheme and advantage that the utility model embodiment will be solved is clearer, will combine accompanying drawing and specific embodiment to be described in detail below.
As shown in Figure 1, a kind of lifting device of the utility model embodiment comprises:
Column 1 is provided with the base 2 that is used for vertical vertical columns 1;
Guidepost 3 is connected with column 1 axial restraint;
Screw mandrel 4 laterally arranges with guidepost 3, is arranged with swivel nut 5, and is in transmission connection with the drive shaft of motor 6;
Movable block 7 is sheathed on the guidepost 3 through slip cap slidably, and is fixedly connected with swivel nut 5;
Lifting arm 8, one ends are fixedly connected with movable block 7, and the other end is provided with and is used for the connection section that is connected with the bio-reactor cover;
Be used to control the electric machine controller 9 that the drive shaft of motor 6 clockwise rotates or rotates counterclockwise, be connected with motor 6.
Suppose that when the drive shaft of motor clockwise rotates also along with clockwise rotating, swivel nut can move towards the top of screw mandrel screw mandrel; When the drive shaft of motor rotated counterclockwise, also along with rotating counterclockwise, swivel nut can move towards the bottom of screw mandrel screw mandrel; At this moment, the method for use of above-mentioned lifting device is:
The operating process of one, mentioning the bio-reactor cover:
The connection section of lifting arm is fixedly connected with the bio-reactor cover;
Starter motor;
Utilize the drive shaft of motor controller controls motor to clockwise rotate; At this moment; Also along with clockwise rotating, swivel nut moves towards the top of screw mandrel screw mandrel, and the movable block that is connected with swivel nut is also followed swivel nut and moved towards the top of screw mandrel; The lifting arm that is connected with movable block also moves along with the top towards screw mandrel, and lifting arm height overhead is increasingly high; Along with lifting arm height overhead is increasingly high, the bio-reactor cover height overhead that is fixedly connected with lifting arm is also increasingly high; Wherein, the rotating speed of the drive shaft of motor can be controlled through electric machine controller, the rotating speed of the drive shaft of motor faster (or slow more), the speed also faster (or slow more) that the bio-reactor cover rises;
Treat that biological reactor tank covers when being raised to proper height, utilize the drive shaft of motor controller controls motor to stop operating, accomplish the operation of mentioning the bio-reactor cover.
Two, fall the operating process of bio-reactor cover:
Starter motor;
Utilize the drive shaft of motor controller controls motor to rotate counterclockwise; At this moment; Also along with rotating counterclockwise, swivel nut moves towards the bottom of screw mandrel screw mandrel, and the movable block that is connected with swivel nut is also followed swivel nut and moved towards the bottom of screw mandrel; The lifting arm that is connected with movable block also moves along with the bottom towards screw mandrel, and lifting arm height overhead is more and more lower; Along with lifting arm height overhead is more and more lower, the bio-reactor cover height overhead that is fixedly connected with lifting arm is also more and more lower; Wherein, the rotating speed of the drive shaft of motor can be controlled through electric machine controller, the rotating speed of the drive shaft of motor faster (or slow more), the speed also faster (or slow more) that the bio-reactor cover descends;
When treating that biological reactor tank lid drops to proper height or covers on the bio-reactor tank deck, utilize the drive shaft of motor controller controls motor to stop operating, accomplish the operation of decline bio-reactor cover.
Swivel nut is towards the lifting device that move on the top of screw mandrel, swivel nut moves towards the bottom of screw mandrel when the drive shaft of motor clockwise rotates when rotating counterclockwise for the drive shaft of motor, and its method of use also can no longer detail with reference to said process here.
To sum up visible; The lifting device that the utility model embodiment provides; Only need the user to utilize the drive shaft of motor controller controls motor to clockwise rotate or rotate counterclockwise; The electric motor driving lead screw transmission mechanism drives lifting arm and rises or descend, thereby realizes that the bio-reactor cover that is fixedly connected with lifting arm rises or descends; Compared with prior art; Utilize simple to operate, the safety of this lifting device handling bio-reactor cover; Labor intensive is few; And reduced the chance that operator contact bio-reactor, and reduced the probability that culture environment is polluted in the bio-reactor, can guarantee the bio-reactor aseptic performance.
Wherein, preferably, connection section is specially interface arrangment or hook pull-up structure; Wherein, interface arrangment is used for the cover of clamping bio-reactor, and cover is fixed on the lifting arm of lifting device; The hook pull-up structure is used to hook the cover of bio-reactor, and cover is fixed on the lifting arm of lifting device.
Wherein, preferably as shown in Figure 2, slip cap 10 is arranged between movable block 7 and the guidepost 3, and is fixedly connected with movable block 7.
Slip cap can reduce the frictional force between movable block and the guidepost, reduces wearing and tearing, and it is too fast to avoid movable block and guidepost to damage.
In addition, preferably as shown in Figure 2 again, above-mentioned lifting device also can comprise:
Be used to the screw rodb base 11 that prevents that screw mandrel 4 from rocking, be arranged at the top of screw mandrel 4;
Top board 12 is fixedly connected with screw rodb base 11 with the top of guidepost 3.
Wherein, screw rodb base specifically can be the plate that there is cylinder shape groove a centre, the vertical form fit of this cylinder shape groove and screw mandrel; The top of screw mandrel is positioned in this cylinder shape groove; Like this, screw mandrel is limited to the position parallel with guidepost by this cylinder shape groove all the time, has prevented that screw mandrel from rocking; In addition, this cylinder shape groove inside also can be provided with abrasion-proof parts such as bearing, when screw mandrel rotates, can reduce the friction between screw mandrel and this cylinder shape groove.
It is thus clear that screw rodb base 11 can keep screw mandrel 4 parallel with guidepost 3 with top board 12, makes lifting device more firm.
Wherein, preferably, screw mandrel is a T type screw mandrel; Swivel nut is a T type swivel nut.
In addition, as shown in Figure 3, the utility model embodiment also provides a kind of bio-reactor, comprising:
Bio-reactor tank body 20;
Lifting device comprises:
Column 1 is provided with the base 2 that is used for vertical vertical columns 1;
Guidepost 3 is connected with column 1 axial restraint;
Screw mandrel 4 laterally arranges with guidepost 3, is arranged with swivel nut 5, and is in transmission connection with the drive shaft of motor 6;
Movable block 7 is sheathed on the guidepost 3 through slip cap slidably, and is fixedly connected with swivel nut 5;
Lifting arm 8, one ends are fixedly connected with movable block 7, and the other end is provided with the connection section that is connected with the bio-reactor cover;
Be used to control the electric machine controller 9 that the drive shaft of motor 6 clockwise rotates or rotates counterclockwise, be connected with motor 6.
Wherein, preferably, above-mentioned slip cap is arranged between movable block and the guidepost, and is fixedly connected (with reference to figure 2) with movable block; See the record of aforementioned relevant slip cap for details.
Wherein, preferably, above-mentioned lifting device also comprises:
Be used to the screw rodb base that prevents that screw mandrel from rocking, be arranged at the top of screw mandrel;
Top board is fixedly connected (with reference to figure 2) with the top of guidepost with screw rodb base; See aforementioned record for details about screw rodb base and top board.
Wherein, preferably, connection section is specially interface arrangment or hook pull-up structure; See the record of aforementioned relevant connection section for details.
Wherein, preferably, screw mandrel is a T type screw mandrel, and swivel nut is a T type swivel nut.
The bio-reactor that the utility model embodiment provides is provided with the lifting device of handling bio-reactor cover automatically; Utilize simple to operate, the safety of this lifting device handling bio-reactor cover; Labor intensive is few; And reduced the chance that operator contact bio-reactor, and reduced the probability that the culture environment in the bio-reactor is polluted, can guarantee the bio-reactor aseptic performance.
The above is the preferred implementation of the utility model; Should be understood that; For those skilled in the art; Under the prerequisite that does not break away from the said principle of the utility model, can also make some improvement and retouching, these improvement and retouching also should be regarded as the protection domain of the utility model.

Claims (10)

1. a lifting device is characterized in that, comprising:
Column is provided with the base that is used for vertically fixing said column;
Guidepost is connected with said column axial restraint;
Screw mandrel laterally arranges with said guidepost, is arranged with swivel nut, and is in transmission connection with the drive shaft of said motor;
Movable block is sheathed on the said guidepost through slip cap slidably, and is fixedly connected with said swivel nut;
Lifting arm, an end is fixedly connected with said movable block, and the other end is provided with and is used for the connection section that is connected with the bio-reactor cover;
Be used to control the electric machine controller that the drive shaft of said motor clockwise rotates or rotates counterclockwise, be connected with said motor.
2. lifting device as claimed in claim 1 is characterized in that,
Said slip cap is arranged between said movable block and the said guidepost, and is fixedly connected with said movable block.
3. lifting device as claimed in claim 1 is characterized in that, also comprises:
Be used to the screw rodb base that prevents that said screw mandrel from rocking, be arranged at the top of said screw mandrel;
Top board is fixedly connected with said screw rodb base with the top of said guidepost.
4. lifting device as claimed in claim 1 is characterized in that,
Said connection section is specially interface arrangment or hook pull-up structure.
5. lifting device as claimed in claim 1 is characterized in that,
Said screw mandrel is a T type screw mandrel, and said swivel nut is a T type swivel nut.
6. a bio-reactor is characterized in that, comprising:
Lifting device comprises:
Column is provided with the base that is used for vertically fixing said column;
Guidepost is connected with said column axial restraint;
Screw mandrel laterally arranges with said guidepost, is arranged with swivel nut, and is in transmission connection with the drive shaft of said motor;
Movable block is sheathed on the said guidepost through sliding shoe slidably, and is fixedly connected with said swivel nut;
Lifting arm, an end is fixedly connected with said movable block, and the other end is provided with the connection section that is connected with the bio-reactor cover;
Be used to control the electric machine controller that the drive shaft of said motor clockwise rotates or rotates counterclockwise, be connected with said motor.
7. bio-reactor as claimed in claim 6 is characterized in that,
Said slip cap is arranged between said movable block and the said guidepost, and is fixedly connected with said movable block.
8. bio-reactor as claimed in claim 6 is characterized in that, said lifting device also comprises:
Be used to the screw rodb base that prevents that said screw mandrel from rocking, be arranged at the top of said screw mandrel;
Top board is fixedly connected with said screw rodb base with the top of said guidepost.
9. bio-reactor as claimed in claim 6 is characterized in that,
Said connection section is specially interface arrangment or hook pull-up structure.
10. bio-reactor as claimed in claim 6 is characterized in that,
Said screw mandrel is a T type screw mandrel, and said swivel nut is a T type swivel nut.
CN 201120490751 2011-11-30 2011-11-30 Lifting device and bioreactor Expired - Fee Related CN202322815U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201120490751 CN202322815U (en) 2011-11-30 2011-11-30 Lifting device and bioreactor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201120490751 CN202322815U (en) 2011-11-30 2011-11-30 Lifting device and bioreactor

Publications (1)

Publication Number Publication Date
CN202322815U true CN202322815U (en) 2012-07-11

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 201120490751 Expired - Fee Related CN202322815U (en) 2011-11-30 2011-11-30 Lifting device and bioreactor

Country Status (1)

Country Link
CN (1) CN202322815U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114591811A (en) * 2022-05-10 2022-06-07 上海芯像生物科技有限公司 Biochemical reaction platform and biochemical reaction system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114591811A (en) * 2022-05-10 2022-06-07 上海芯像生物科技有限公司 Biochemical reaction platform and biochemical reaction system

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20120711

Termination date: 20161130