CN202135203U - Biological chip scanner - Google Patents

Biological chip scanner Download PDF

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Publication number
CN202135203U
CN202135203U CN 201120257275 CN201120257275U CN202135203U CN 202135203 U CN202135203 U CN 202135203U CN 201120257275 CN201120257275 CN 201120257275 CN 201120257275 U CN201120257275 U CN 201120257275U CN 202135203 U CN202135203 U CN 202135203U
Authority
CN
China
Prior art keywords
biochip
probe
bearing platform
computer system
image scanning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN 201120257275
Other languages
Chinese (zh)
Inventor
伯晓晨
王升启
肖瑞
朱坤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Puruikang Bio Technology Co ltd
Institute of Radiation Medicine of CAMMS
Original Assignee
Shenzhen Puruikang Bio Technology Co ltd
Institute of Radiation Medicine of CAMMS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Puruikang Bio Technology Co ltd, Institute of Radiation Medicine of CAMMS filed Critical Shenzhen Puruikang Bio Technology Co ltd
Priority to CN 201120257275 priority Critical patent/CN202135203U/en
Application granted granted Critical
Publication of CN202135203U publication Critical patent/CN202135203U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model provides a biological chip scanner, composed of a chip load-bearing platform, a mechanical transmission system, an image scanning system, a control system and a software analysis system. The chip load-bearing platform is equipped with a biological chip accommodating space, and the mechanical transmission system comprises a stepping motor, a transmission device and a scanning head fixing device; the scanning head fixing device is equipped with a scanning head, the stepping motor drives the scanning head to move via the transmission device, and the image scanning system comprises a scanning head, a photoelectric converting circuit, an A/D converting circuit and a data transmission line; the scanning head acquires image data of the biological chip, and then the image data is converted by the photoelectric converting circuit, and finally a signal is outputted by the data transmission line; the control system is composed of a motion control module and an interface data transmission module and controls other parts to move harmoniously and consistently; the software analysis system is composed of an upper computer system and a lower computer system, the lower computer system is connected with the upper computer system via a wired or wireless mode, acquires the image data of the biological chip and transmits the image data to the upper computer system to process.

Description

A kind of biochip scanner
Technical field
The utility model belongs to the biochip test field, particularly relates to a kind of biochip scanner.
Background technology
The visual biochip that is labeled as the basis with nanometer has the advantages that cost is low, signal is strong, highly sensitive, is the new bio chip with bright market prospects.The external large scale commercial product multifunction scanner that laboratory research is adopted costs an arm and a leg, and bulky, installation complicacy is difficult to apply.See from the field quick detection technological layer, to simple in structure, price is appropriate and it is very urgent to be convenient to the checkout equipment demand that the individual carries.Also do not have and the matching used scanner of visual biochip in the market with special optical structure.
The utility model content
The purpose of the utility model is to overcome the deficiency of prior art, and a kind of simple in structure, detection efficiency is high, sweep speed is fast biochip scanner is provided.
To achieve these goals, the technical scheme of employing is following.
A kind of biochip scanner; Constitute by chip bearing platform, machine driven system, image scanning system, control system, software analysis system; Said chip bearing platform is provided with the biochip accommodation space; Said machine driven system comprises stepping motor, transmission device and probe fixture, and the probe fixture is installed probe, and stepping motor is through the motion of actuator drives probe; Said image scanning system comprises probe, photoelectric switching circuit, A/D change-over circuit and data transmission link; Probe is gathered the view data of biochip, and through data transmission link output signal, said control system is made up of motion-control module and interface data transmission module by photoelectric switching circuit conversion back; It controls the harmonious of other parts running; Said software analysis system is made up of master system and lower computer system, and lower computer system adopts wired or wireless mode to connect master system, and lower computer system obtains the view data of biochip and this image data transmission is handled to master system.
In the technique scheme, said chip bearing platform, machine driven system, image scanning system, control system, lower computer system are arranged on airtight enclosure interior.
Further, the probe of said image scanning system disposes high diffuse light spectrum planar light source.
Said machine driven system also is provided with the displacement transducer of confirming movement position.
Said housing comprises upper cover plate, middle loading plate and base plate, and said upper cover plate and middle loading plate upper surface constitute the chip bearing platform, and the lower surface of middle loading plate and base plate constitute the space that is provided with of machine driven system and image scanning system.
Said chip bearing platform evenly is pasted with optical sheet at upper cover plate and middle loading plate upper surface, and the optical sheet bottom surface that upper cover plate is pasted is provided with luminescence unit and spectral filtering film, the planar light source of formation and probe configuration.
The photoelectric switching circuit of said image scanning system, A/D change-over circuit are integrated on the circuit board, and are sealed in the casing.
The utility model except that have apparatus structure simply, also have the linear wide ranges of test, open advantage.
Description of drawings
Fig. 1 is the structural representation of the utility model.
Fig. 2 is the C-C cutaway view of the utility model.
Fig. 3 is the A-A cutaway view of the utility model.
Fig. 4 is the B-B cutaway view of the utility model.
Embodiment
Below in conjunction with accompanying drawing the utility model is done further explanation.
The utility model comprises chip bearing platform, machine driven system, image scanning system, control system, software analysis system five parts.Chip bearing platform top is used for the biochip location places, and the bottom is used for fixing displacement transducer; Machine driven system mainly is made up of stepping motor, synchronous belt, unidirectional line slideway, probe fixture; Image scanning system is grouped into by private use plane light source scanning head, photoelectric switching circuit, a data transfer part; The software analysis system is made up of host computer procedure and program of lower computer, and through USB interface slave computer output image data, host computer is handled the view data from slave computer.
The structure of the utility model is shown in accompanying drawing 1-4, and the upper cover plate 1 of chip bearing platform 8, following table 3 all are pasted with the airtight optical sheet of having of special processing, wherein; The bottom surface of upper cover plate 1 optics flat-form material is stained with spectral filtering film 2; Earlier chip bearing platform 8 upper cover plates 1 are opened, biochip to be measured is put into following table 3 draw-in grooves, cover upper cover plate 1 then; Guarantee airtight, guarantee to obtain visual biochip test scan image.The bottom surface of upper cover plate optics flat-form material has the luminescence unit that 6 semiconductive luminescent materials are made; And with the compound stickup of optical base-substrate that has spectral filtering film and texturing treated side; Be configured for the private use plane light source that visual biochip test scanning is used, promptly high diffuse light spectrum planar light source.It is more even that high diffuse light spectrum planar light source has central service area brightness, and the planar light of the short passband spectrum of visual biochip test scanning optical spectrum specification requirement is satisfied in emission.The planar light of the short passband spectrum of this kind is to detector spectral response characteristic and nano-probe biochip spectral detection characteristics, is target and specifically designing to improve scanning resolution.
Machine driven system is guaranteed probe 7 accurate moving by stepping motor 4, be with 5 and the 6 accurate transmissions of unidirectional line slideway synchronously, and movement position is confirmed by displacement transducer.
Image scanning system is made up of probe 7, photoelectric switching circuit 10, A/D change-over circuit 11, a data line with high diffuse light spectrum planar light source.Through probe 7 images acquired, through corresponding change-over circuit output signal, its photoelectric switching circuit 10, A/D change-over circuit 11 etc. are integrated on the circuit board, and are sealed in the airtight casing 9.It is more even that high diffuse light spectrum planar light source on the probe 7 has central service area brightness, and the planar light of the short passband spectrum of visual biochip test scanning optical spectrum specification requirement is satisfied in emission.After the control system switching signal, through USB interface test data is transferred to PC and handles so that let the user understand the result.Described biochip location placement direction is parallel along the reciprocal traffic direction of slide rail with probe.
Described control system partly is made up of motion-control module and interface data transmission.Its effect is that each parts of control move harmoniously, with the view data that reads with resolution is handled or conversion is required arbitrarily resolution.Reliable and stable through little process chip control integrated circuit plate power supply.
Said software systems are made up of host computer procedure and program of lower computer, and through USB interface slave computer output image data, host computer is handled the data from slave computer.
The course of work of the utility model is: after detection chip is put into following table 3 draw-in grooves; High diffuse light spectrum planar light source; The transmission detection of biological chip at the top; Signal driven sweep through control system 7 on unidirectional line slideway 6 with the visual biochip parallel motion of nano-probe to be detected, form scanning plane, obtain visual biochip test scan image.High diffuse light spectrum planar light source is according to different visual biochip test needs, and its light intensity contrast ratio need be debugged.Through after image scanning system carries out image capture, the software analysis system that directly data is sent into host computer carries out related data and handles.
Biochip location placement direction is parallel along unidirectional line slideway 6 traffic directions with probe 7, and scanning means drags through synchronous belt, realizes the process of linear scan through the slip on unidirectional line slideway 6.

Claims (8)

1. biochip scanner; It is characterized in that constituting by chip bearing platform, machine driven system, image scanning system, control system, software analysis system; Said chip bearing platform is provided with the biochip accommodation space; Said machine driven system comprises stepping motor, transmission device and probe fixture, and the probe fixture is installed probe, and stepping motor is through the motion of actuator drives probe; Said image scanning system comprises probe, photoelectric switching circuit, A/D change-over circuit and data transmission link; Probe is gathered the view data of biochip, and through data transmission link output signal, said control system is made up of motion-control module and interface data transmission module by photoelectric switching circuit conversion back; It controls the harmonious of other parts running; Said software analysis system is made up of master system and lower computer system, and lower computer system adopts wired or wireless mode to connect master system, and lower computer system obtains the view data of biochip and this image data transmission is handled to master system.
2. biochip scanner according to claim 1 is characterized in that said chip bearing platform, machine driven system, image scanning system, control system, lower computer system are arranged on airtight enclosure interior.
3. biochip scanner according to claim 1 and 2 is characterized in that the probe of said image scanning system disposes high diffuse light spectrum planar light source.
4. biochip scanner according to claim 1 and 2 is characterized in that said machine driven system also is provided with the displacement transducer of confirming movement position.
5. biochip scanner according to claim 2; It is characterized in that said housing comprises upper cover plate, middle loading plate and base plate; Said upper cover plate and middle loading plate upper surface constitute the chip bearing platform, and the lower surface of middle loading plate and base plate constitute the space that is provided with of machine driven system and image scanning system.
6. biochip scanner according to claim 5; It is characterized in that said chip bearing platform evenly is pasted with optical sheet at upper cover plate and middle loading plate upper surface; And the optical sheet bottom surface that upper cover plate is pasted is provided with luminescence unit and spectral filtering film, constitutes the planar light source with the probe configuration.
7. biochip scanner according to claim 6 is characterized in that photoelectric switching circuit, the A/D change-over circuit of said image scanning system is integrated on the circuit board, and is sealed in the casing.
8. biochip scanner according to claim 5 is characterized in that said middle loading plate upper surface is provided with four grooves, as the accommodation space of placing 4 biochips.
CN 201120257275 2011-07-20 2011-07-20 Biological chip scanner Expired - Fee Related CN202135203U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201120257275 CN202135203U (en) 2011-07-20 2011-07-20 Biological chip scanner

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201120257275 CN202135203U (en) 2011-07-20 2011-07-20 Biological chip scanner

Publications (1)

Publication Number Publication Date
CN202135203U true CN202135203U (en) 2012-02-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 201120257275 Expired - Fee Related CN202135203U (en) 2011-07-20 2011-07-20 Biological chip scanner

Country Status (1)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103983573A (en) * 2014-05-22 2014-08-13 中国科学院光电技术研究所 Two-dimensional scanning method for biological chip scanner
CN104237544A (en) * 2014-09-28 2014-12-24 博奥生物集团有限公司 Biological chip detector

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103983573A (en) * 2014-05-22 2014-08-13 中国科学院光电技术研究所 Two-dimensional scanning method for biological chip scanner
CN104237544A (en) * 2014-09-28 2014-12-24 博奥生物集团有限公司 Biological chip detector
CN104237544B (en) * 2014-09-28 2016-05-11 博奥生物集团有限公司 A kind of biochip test device

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120201

Termination date: 20150720

EXPY Termination of patent right or utility model