CN202083704U - Full-automatic loading device - Google Patents
Full-automatic loading device Download PDFInfo
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- CN202083704U CN202083704U CN2011201849101U CN201120184910U CN202083704U CN 202083704 U CN202083704 U CN 202083704U CN 2011201849101 U CN2011201849101 U CN 2011201849101U CN 201120184910 U CN201120184910 U CN 201120184910U CN 202083704 U CN202083704 U CN 202083704U
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Abstract
The utility model discloses a full-automatic loading device which belongs to the field of bioanalysis instruments. The full-automatic loading device is characterized in that: in a sampling arm mechanism, the inner end of a sampling arm crossbeam is fixed with the sampling arm; the outer end of the sampling arm is fixed with a conical sampling head loading mechanism; a horizontal rotating tooth is fixed on the sampling arm and is engaged with a rotating tooth of a motor rotating horizontally; a motor rotating vertically is matched with a screw in a transmission way; a vertical rotating tooth is fixed on the sampling arm; the screw is matched with the vertical rotating tooth in a transmission way; in a sample reagent mechanism, a sample position hole and a standard hole are respectively arranged on a disc sample and a reagent disc; the sample and the reagent disc are matched with a stepping motor in a transmission way through a shaft; and a concave clamping slot for unloading the sampling head is mounted on the lateral side of the sample and the reagent disc. The full-auto loading device has the beneficial effects that: the full-automatic loading device has the characteristics of high precision, good stability as well as convenience in operation and control, etc. Moreover, zero cross contamination between samples is really realized; and the reliability of enzyme immunodetection is improved. As the adopted sampling head does not need to have conductivity, the running cost is reduced.
Description
Technical field
The utility model belongs to the bio-analysis instrument field, relates to the improvement of the equipment of work such as a kind of distribution that is used for biological specimen and reagent, dilution, mixing.
Background technology
Full-automatic loading device is apparatus operating such as the distribution that is used for full-automatic sample, dilution, mixing, can be used for all the automated fluid application of sample work in the processes such as medical test, food testing, biological experiment, specifically mainly comprise: enzyme labeled immunoassay analysis (ELISA), the processing of chemiluminescence immune assay (CLIA) experiment sample, the processing of blood group analyzing samples etc.The accuracy aspect imbibition, separatory of existing domestic equipment is also not high, and overseas equipment costs an arm and a leg.Also there is the problem that occurs cross pollution between sample easily in existing in addition loading device, has a strong impact on finishing of related work.
ELISA and CLIA are the conventionally test methods that adopts clinically at present, at present main test process is, on 96 orifice plates, carry out the interpolation of sample and reagent by hand, transfer to then in other equipment and hatch, wash plate, work such as DATA REASONING, the link that in whole process, adds sample and reagent, the workload maximum, its application of sample precision and position accuracy play critical effect in whole testing process, at present domestic in middle-size and small-size medical institutions since condition restriction application of sample process finish by manual entirely, there is the phenomenon that adds wrong sample and application of sample low precision etc., have a strong impact on testing result, and the sample adding system of import exists the expense costliness, volume is big, complicated operation, drawbacks such as maintenance cost height are difficult to be popularized.
Summary of the invention
The purpose of this utility model is: a kind of full-automatic sample adding device is provided, and it has precision height, good stability, controls characteristics such as convenient in the robotization application of sample process of imbibition, separatory.
The technical solution of the utility model is: it is made up of sampling head and 96 orifice plate loader mechanisms, sample reagent mechanism and sampling arm mechanism three parts, this three part all is fixed on the base plate, and sampling arm mechanism is fixed in the middle of sampling head and 96 orifice plate loading areas and the sample reagent district.
In sampling head and 96 orifice plate loader mechanisms, sampling head and 96 holes are loaded plate and are fixed on the base plate by frame, and sampling head and 96 holes are loaded plate and dragged by stepper motor can to do the plane on frame to move.
In sampling arm mechanism, inner and the sampling arm vertical fixing of sampling arm crossbeam, sampling arm crossbeam outer end and taper sampling head loader mechanism vertical fixing, the level that is fixed with on the sampling arm is changeed tooth, and with horizontally rotate motor and change the tooth engagement, the vertical rotation motor cooperates with screw drive, is fixed with vertical commentaries on classics tooth on the sampling arm, and screw rod cooperates with the transmission of vertical commentaries on classics tooth.
In sample reagent mechanism, on disc sample, reagent dish, have hole, sample position and gauge orifice, sample, reagent dish are fixed on the base plate by stand, sample, reagent dish cooperate with the stepper motor transmission by axle, and the draw-in groove of the unloading sampling head of a spill is installed at the side of sample, reagent dish.
On sampling head and 96 orifice plates, have big sampling head and load hole and little sampling head loading hole.
The bottom of taper sampling head loader mechanism cooperates with little sampling head bottleneck elastic gap, and the middle part of taper sampling head loader mechanism cooperates with big sampling head bottleneck elastic gap.
The beneficial effects of the utility model are: have precision height, good stability, control characteristics such as convenient, adopt the application of sample assembly of forming by disposable sampling head, high sensitivity pressure transducer simultaneously, zero cross-contamination between real realization sample has improved the reliability of the inspection-free survey of enzyme.And the sampling head that adopts is that common sampling head does not need to possess conductive capability, greatly reduces the operating cost of equipment.
Description of drawings
Fig. 1 is the utility model structural drawing;
Fig. 2 is the utility model sampling head and 96 orifice plate loader mechanism vertical views;
Fig. 3 is the utility model sampling arm mechanism structure figure;
Fig. 4 is the utility model sample reagent mechanism structure figure.
Embodiment
Below in conjunction with accompanying drawing the utility model is described further:
Shown in Figure 1, the 1st, floor, the 11st, plate, the 12nd is loaded in sampling head and 96 holes, frame, the 13rd, stepper motor A, the 21st, sampling arm crossbeam, the 22nd, sampling arm, the 23rd, taper sampling head loader mechanism, the 24th changes tooth, the 25th, horizontally rotates motor, the 26th, and vertical rotation motor, the 27th vertically changes tooth, the 28th, screw rod, the 31st, sample, reagent dish, the 32nd, stand, the 33rd, stepper motor B, the 34th, the draw-in groove of unloading sampling head.
The loading of 96 orifice plates and the loading of sampling head mainly are responsible in 96 orifice plates and sampling head loading area moving region.Reagent, sample zone are mainly used to place sample, reagent and corresponding standard product and quality-control product etc.Sampling arm mainly comprises gear trains such as ram pump, pressure transducer and the motor of being correlated with, gear, realized having the high-accuracy sampling mechanism of level detection function, adopt this level sensor to have realized the detecting liquid level of common sampling head simultaneously, avoided adopting the cross pollution of draw point and adopted the expensive of disposable sampling head with electric conductivity.The implementation of whole instrument is just carried out around above 3 zones.
96 orifice plates and sampling head loading area are mainly used to place sampling head and treat 96 orifice plates of application of sample as shown in Figure 2, comprise big sampling head loading area totally 10 positions, being used for the placement capacity is the big sampling head of 1000 μ l, be used for realizing a large amount of suction samples of general sample, repeatedly setting-out, the work efficiency of raising equipment.Little sampling head loading area is used for placing little sampling head, and totally 96 are used for drawing and discharge sample, and sample is with a sampling head.96 orifice plate put areas are used for placing 96 orifice plates for the treatment of application of sample.
Be illustrated in figure 3 as sampling arm mechanism, by the vertical rotation motor with horizontally rotate the driven by motor sampling arm and move up and down and left-right rotation.The sampling head loader mechanism is divided into two parts, and big sampling head " loaded " position is at the middle part, and little sampling head " loaded " position is used for loading the sampling head of different capabilities respectively in the bottom.The piston of ram pump (not embodying among the figure) moves suction sample and the setting-out that has realized sampling probe, and pressure transducer (not embodying among the figure) is monitored the variation of the pressure in the sampling head in real time, in case there is pressure to change, then expression has detected liquid level.This liquid level sensor has the detection sensitivity height, is subjected to characteristics such as external interference is little.
Be illustrated in figure 4 as sample, reagent dish, comprise that mainly the sample position is used for placing sample or standard etc., totally 96, the reagent position is used for placing reagent, and the capacity of each is 10ml, totally 15 positions.
Sampling procedure is:
1, sampling arm rotates drive sampling head loader mechanism and moves to ELISA Plate and sampling head zone, and sampling head and 96 orifice plates load plate and move the relevant position, and sampling arm descends and gets a sampling head.
2, sampling arm turns to sample, reagent dish, behind this a certain amount of sample of taking a sample, and the rotation of rising, sampling head and 96 orifice plates load plate and move the relevant position, the sampling arm setting-out,
3, sampling arm forwards the draw-in groove place of sampling head unloading sampling head to, the unloading sampling head,
4, repeat 1,2,3 actions, finish the application of sample process of whole setting,
5, sampling arm rotates drive sampling charger and moves to sampling head and 96 holes loading plate, and sampling head and 96 holes are loaded plate and moved the relevant position, and sampling arm descends and gets a sampling head.
6, forward reagent area to, once get a certain amount of public reagent,
7, sampling arm forwards sampling head and 96 holes loading plate to, and it is a certain amount of to carry out setting-out,
8, sampling arm is motionless, and sampling head and 96 holes are loaded plate and moved to another position, hole, and setting-out is a certain amount of again, repeats this action.
9, repeat 5,6,7,8 actions and finish the application of sample that whole plate is provided with.
Claims (3)
1. full-automatic sample adding device is characterized in that:
In sampling head and 96 orifice plate loader mechanisms, sampling head and 96 orifice plates load plate and are fixed on the base plate by frame, and sampling head and 96 orifice plates load plate and dragged by stepper motor can to do the plane on frame to move;
In sampling arm mechanism, inner and the sampling arm vertical fixing of sampling arm crossbeam, sampling arm crossbeam outer end and taper sampling head loader mechanism vertical fixing, the level that is fixed with on the sampling arm is changeed tooth, and with horizontally rotate motor and change the tooth engagement, the vertical rotation motor cooperates with screw drive, is fixed with vertical commentaries on classics tooth on the sampling arm, and screw rod cooperates with the transmission of vertical commentaries on classics tooth;
In sample reagent mechanism, on disc sample, reagent dish, have hole, sample position and gauge orifice, sample, reagent dish are fixed on the base plate by stand, sample, reagent dish cooperate with the stepper motor transmission by axle, and the draw-in groove of the unloading sampling head of a spill is installed at the side of sample, reagent dish.
2. a kind of full-automatic sample adding device according to claim 1 is characterized in that: have big sampling head and load hole and little sampling head loading hole on sampling head and 96 orifice plates.
3. a kind of full-automatic sample adding device according to claim 1 is characterized in that: the bottom of taper sampling head loader mechanism cooperates with little sampling head bottleneck elastic gap, and the middle part of taper sampling head loader mechanism cooperates with big sampling head bottleneck elastic gap.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011201849101U CN202083704U (en) | 2011-06-03 | 2011-06-03 | Full-automatic loading device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011201849101U CN202083704U (en) | 2011-06-03 | 2011-06-03 | Full-automatic loading device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202083704U true CN202083704U (en) | 2011-12-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011201849101U Expired - Fee Related CN202083704U (en) | 2011-06-03 | 2011-06-03 | Full-automatic loading device |
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| Country | Link |
|---|---|
| CN (1) | CN202083704U (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104020010A (en) * | 2013-03-01 | 2014-09-03 | 天津出入境检验检疫局工业产品安全技术中心 | FTA card sampling device |
| CN104914265A (en) * | 2015-05-25 | 2015-09-16 | 李昌伟 | Full-automatic urine analyzer |
| CN104950124A (en) * | 2015-05-25 | 2015-09-30 | 李昌伟 | Full-automatic dry chemical method detector and constant-temperature conservation detection unit thereof |
| CN105092868A (en) * | 2015-09-12 | 2015-11-25 | 丁鸿 | Rotary type integrated structure for sample and reagent positions by coagulation analyzer |
| CN105754842A (en) * | 2016-04-29 | 2016-07-13 | 珠海迪尔生物工程有限公司 | Cold-chain storage and extraction type auxiliary reagent adding device |
| CN107044922A (en) * | 2017-01-20 | 2017-08-15 | 广东顺德工业设计研究院(广东顺德创新设计研究院) | Sampler |
| CN107966583A (en) * | 2017-12-26 | 2018-04-27 | 北京博晖创新光电技术股份有限公司 | A kind of autosampler based on kit |
| CN108048318A (en) * | 2017-12-21 | 2018-05-18 | 江苏集萃智能制造技术研究所有限公司 | A kind of culture solution adds equipment automatically |
| CN110567753A (en) * | 2019-09-19 | 2019-12-13 | 四川大学 | Plant rhizosphere trace device of fetching earth |
| CN111796065A (en) * | 2020-09-09 | 2020-10-20 | 南京宏佳金属制品有限公司 | A food check out test set for food sampling detects |
-
2011
- 2011-06-03 CN CN2011201849101U patent/CN202083704U/en not_active Expired - Fee Related
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104020010A (en) * | 2013-03-01 | 2014-09-03 | 天津出入境检验检疫局工业产品安全技术中心 | FTA card sampling device |
| CN104020010B (en) * | 2013-03-01 | 2016-06-08 | 天津出入境检验检疫局工业产品安全技术中心 | A kind of FTA card sampler |
| CN104914265A (en) * | 2015-05-25 | 2015-09-16 | 李昌伟 | Full-automatic urine analyzer |
| CN104950124A (en) * | 2015-05-25 | 2015-09-30 | 李昌伟 | Full-automatic dry chemical method detector and constant-temperature conservation detection unit thereof |
| CN105092868A (en) * | 2015-09-12 | 2015-11-25 | 丁鸿 | Rotary type integrated structure for sample and reagent positions by coagulation analyzer |
| CN105754842A (en) * | 2016-04-29 | 2016-07-13 | 珠海迪尔生物工程有限公司 | Cold-chain storage and extraction type auxiliary reagent adding device |
| CN107044922A (en) * | 2017-01-20 | 2017-08-15 | 广东顺德工业设计研究院(广东顺德创新设计研究院) | Sampler |
| CN108048318A (en) * | 2017-12-21 | 2018-05-18 | 江苏集萃智能制造技术研究所有限公司 | A kind of culture solution adds equipment automatically |
| CN107966583A (en) * | 2017-12-26 | 2018-04-27 | 北京博晖创新光电技术股份有限公司 | A kind of autosampler based on kit |
| CN110567753A (en) * | 2019-09-19 | 2019-12-13 | 四川大学 | Plant rhizosphere trace device of fetching earth |
| CN110567753B (en) * | 2019-09-19 | 2022-03-11 | 四川大学 | Plant rhizosphere trace device of fetching earth |
| CN111796065A (en) * | 2020-09-09 | 2020-10-20 | 南京宏佳金属制品有限公司 | A food check out test set for food sampling detects |
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| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20111221 Termination date: 20120603 |