CN202078618U - Pulse oscillation and atomization sputum inducing device - Google Patents

Pulse oscillation and atomization sputum inducing device Download PDF

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Publication number
CN202078618U
CN202078618U CN2011201711407U CN201120171140U CN202078618U CN 202078618 U CN202078618 U CN 202078618U CN 2011201711407 U CN2011201711407 U CN 2011201711407U CN 201120171140 U CN201120171140 U CN 201120171140U CN 202078618 U CN202078618 U CN 202078618U
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China
Prior art keywords
sputum
oscillation
patient
atomization
induction
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Expired - Fee Related
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CN2011201711407U
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Chinese (zh)
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马德东
肖伟
鹿洪秀
李文培
张一�
邢影
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Shandong University
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Shandong University
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Abstract

The utility model discloses a pulse oscillation and atomization sputum inducing device, which comprises an ultrasonic generator, an oscillation sound generator, a liquid medicine container and a control circuit. The ultrasonic generator and the oscillation sound generator are respectively connected with the control circuit, the ultrasonic generator is connected with the liquid medicine container, and the liquid medicine container is provided with a catheter. During usage, sterilizing saline with specific concentration is added in the liquid medicine container, an outlet catheter shared by the liquid medicine container and the oscillation sound generator is placed in the mouth of a patient, when the pulse oscillation and atomization sputum inducing device begins to work, the ultrasonic generator can adjust ultrasonic frequency, so that sizes of atomization particles are controlled according to needs, the oscillation sound generator can adjust and select oscillation wave modes and frequencies, accordingly parameters for the patient feeling comfortable are selected, and the optimum effect is guaranteed. The pulse oscillation and atomization sputum inducing device simultaneously has atomization and oscillation functions, oscillation with special frequency is provided for the mouth of the patient while the patient sucks the saline and the saline is atomized, so that sputum is prompted to be discharged, inducing success rate is increased, inducing time is shortened, and danger is reduced. The pulse oscillation and atomization sputum inducing device has the advantages of simple structure, fine service effect and the like.

Description

A kind of pulse oscillating atomizing induction of sputum device
Technical field
This utility model relates to a kind of pulse oscillating atomizing induction of sputum device.
Background technology
Induction of sputum (induced sputum) is to allow the person under inspection of no spontaneous expectoration or few expectorant suck hypertonic saline, induces the person under inspection to produce the capacity sputum, thus the method that can detect or study lower respiratory tract secretions.Along with cytology and microbiological generation and development, the critical role of sputum examination in diagnosis lung tumors and infection also consolidated day by day.Dr Morrow Brown in 1958 is used for the induction of sputum technology assessing in the eosinophilic granulocyte's ratio and the research of patient to the relation of hormone-sensitive degree of sputum first.Method after Pin in 1992 etc. will improve is used for the airway inflammation situation that induction of sputum is analyzed asthmatic patient.2002, Europe was breathed association and has been worked out induction of sputum operation and guide detection, has established the status of induction of sputum in clinical diagnosis and scientific research more.
The mechanism of induction of sputum is still not fully aware of, may pass through: 1. hypertonic saline irritative cough promotes that moisture flows to tube chamber under the mucosa; 2. make mucus thinning, slime layer is taken away by cilium easily, thereby increases the mucosa clearance rate; 3. promote the secretion of mucosa body of gland and promote mechanism such as the mucous discharge of airway surface and produce sputum.The acquisition methods of induction of sputum is to allow the person under inspection suck the hypertonic saline of fixed concentration (as 3% or 4.5%) or progressive concentration (3%, 4%, 5%), behind person under inspection's cleaning oral cavity, encourages person under inspection's cough, collects sputum to sterile vessel.Have and discover that the induction of sputum specimen more can represent the cell component and the inflammation situation of lower respiratory tract than the specimen of the spontaneous expectoration of patient, and the saline of variable concentrations can not influence total cellular score and cell divide in the induction of sputum.POPOV etc. find that non-squamous cell content is higher than spontaneous expectoration in the induction of sputum, smear better quality behind the cell centrifugation, and cell counting is more reliable; PIZZICHINI compares research to asthmatic patient induction of sputum and spontaneous expectoration, finds that both proportion, total cellular score, non-squamous cell ratio levels are similar, the more spontaneous expectoration height of living cells ratio in the induction of sputum.
The induction of sputum inspection has critical role to the clinical diagnosis of various respiratory tract disease.1958, Bicherman was applied to the method for induction of sputum the diagnosis of lung tumors the earliest.Agusti etc. studies show that the more spontaneous expectoration of induction of sputum can improve the diagnosis of small occupy-place, are the effective technology of diagnosis peripheral type pulmonary carcinoma, especially for the existing patient who shifts the patient and complication is arranged.Other studies show that patients with lung cancer induction of sputum Telomerase Activity is apparently higher than the benign lesion person of pulmonary, and the quantitative assay of prompting induction of sputum Telomerase Activity helps the Differential Diagnosis of tumor.The induction of sputum technology is with its safe noinvasive, and easily the advantage of being accepted by the patient becomes one of important means of lung tumors diagnosis.Finding Mycobacterium tuberculosis in respiratory secretions is the phthisical primary foundation of diagnosis, but that expectorant is looked into the method susceptiveness of acid-fast bacilli is not high, and lunger expectoration person only accounts for 40%, has limited the application of this method.Carry out induction of sputum for no expectorant person, parallel bacteriology checking can improve recall rate greatly, helps phthisical diagnosis, estimates therapeutic effect and judging prognosis.McWilliams etc. are coated with capable respectively induction of sputum inspection of negative doubtful lunger or fiberoptic bronchoscopy to 129 no expectorant of example or expectorant, what make a definite diagnosis by fibre bronchus mirror is 1 example, and rely on 13 examples that have that induction of sputum makes a definite diagnosis, and this other check result of 13 routine patient is all positive.Induction of sputum result's positive rate is apparently higher than fibre bronchus mirror, and the induction of sputum inspection fee is starkly lower than fibre bronchus mirror.Low respiratory tract bacterial infection is a kind of clinical common disease, and for no expectorant patient, pathogen is determined difficulty, and induction of sputum can make no expectorant or few expectorant patient expectoration expectorant, and the pathogen type of energy direct reaction airway secretions existence, has increased the recall rate of pathogen.The diagnosis of asthma mainly relies on clinical manifestation and pulmonary function test, and induction of sputum detect can the direct reaction patient airway inflammatory conditions, in the diagnosis of asthma and treatment, play a significant role.Studies show that, induce eosinophil count in the sputum, the horizontal asthma group of ECP apparently higher than the normal healthy controls group, in, severe asthma is than mild asthma patient Geng Gao, and eosinophil count and pulmonary function FEV1, FEV1/FVC be negative correlation, is proportionate with clinical score.When acute exacerbations of asthma, eosinophil count obviously increases in the sputum.
The induction of sputum technology plays a significant role in the scientific research of respiratory tract disease as a kind of easy, safe method.Studies confirm that in a large number IL-8, TNF-α, II-6 concentration are significantly higher than asthma group and normal healthy controls group in COPD patient's induction of sputum.Roland etc. discover that Endothelin in COPD patient's induction of sputum (ET) concentration is significantly higher than matched group, and are negative correlation with pulmonary function FEV1, and infer that the ET receptor antagonist may be the new way of a kind of COPD of treatment.Junanita etc. studies show that gently, the level of MMP-8, MMP-9 is significantly higher than matched group in the moderate COPD patient induction of sputum, be proportionate with the air flue limited degree, and relevant with neutrophilic granulocyte.Reports such as Leigh are full of the pulmonary macrophage of hemosiderin during induction of sputum technology for detection left heart insufficiency, whether the dyspnea that will help to differentiate COPD patient exists heart source property disease.In the asthma Study on Pathogenesis, the induction of sputum technology also is a kind of good research means, application RT-PCR such as Hamzaoui and ELISA method have been studied the induction of sputum composition of acute exacerbation phase asthmatic patient, find with normal group contrast back, the IL-10 of Th2 emiocytosis and IL-4mRNA express obviously and strengthen, and the IL-2 of Th1 emiocytosis and IFN2-α no change illustrate that the Th2 cell plays a crucial role in the asthma pathogenesis.Komai etc. discover that stable phase asthmatic patient air flue contains IL-8, and the concentration of IL-8 obviously increases in the induction of sputum when asthma increases the weight of, and show that IL-8 participates in the pathogenesis of asthma process.Panzer etc. discover that lymphocyte in the asthmatic patient induction of sputum, Eos counting and the oxyphil cell neurotoxin level of deriving has Changing Pattern round the clock, to be low in high afternoon in the morning, consistent with the pulmonary function variation, phenomenon that this prompting asthma state of an illness changes round the clock may change relevant with airway inflammation round the clock.
Atomizing suction apparatus now commonly used has two kinds of ultrasound atomizer and gas compression atomizing devices, and both differences only are to make the principle difference.The ultimate principle of ultrasonic atomization technique: the oscillator signal from main circuit board is carried out the energy amplification by large power triode, pass to ultrasonic wafer, the ultrasound wave wafer is converted into ultrasonic energy to electric energy, ultrasonic energy can be atomized into the small droplet of 1um to 5um to water soluble drug at normal temperatures, with water is medium, utilizes ultrasonic directed pressure with water solublity medicinal liquid atomisation, by inner blower fan wind-force, medicinal liquid is sprayed into patient airway, sucked by the patient again.The ultimate principle of gas compression atomization technique: the compressor (less than 25 decibels) that adopts the energy-saving and low-noise patented technology to make, utilize compressor netting continuous basic one powerful air-flow of filterable pure air boil down to by the liquid in jet the impulse liquid medicine cup that gushes out by antibiotic, with its liquid medicine gasification, suck for mouth and nose by the fog outlet ejection again.
Although obtaining induction of sputum is safe to most of persons under inspection, but because hypertonic saline is a kind of bronchus exciting agent, can cause that air flue shrinks, thus there is certain danger, especially for the asthma of not controlling fully and the patient of acute exacerbation of chronic obstructive pulmonary disease.Sutherland etc. discover that code requirement reduces phlegm under the tight monitoring and induce operating process, and centering, severe stable phase COPD patient success rate reach 83.3%, and Tsoumakidou etc. reach 95% and 93% respectively with report success rates such as Vlachos-Mayer.Kelley etc. discover that the patient is shorter to highoutput nebulizer tolerance time, and the tolerance time that hangs down the output nebulizer for (12.7 ± 2.0) min is (16.5 ± 1.8) min (P=0.02).In addition, some person under inspection's expectoration difficulty even increase the sputum that the atomizing respiratory time also is difficult to receive capacity, and increases nebulisation time to the person under inspection, and especially asthma or COPD patient probability that untoward reaction takes place increases.
Summary of the invention
At above-mentioned prior art, this utility model provides a kind of pulse oscillating atomizing induction of sputum device, it has the device of atomizing and concussion function simultaneously, suck the brinish while of atomizing the patient, give the Sasser of characteristic frequency and waveform, promote sputum to discharge, improve and induce success rate, shorten induction time, reduce dangerous.
This utility model is achieved through the following technical solutions:
A kind of pulse oscillating atomizing induction of sputum device, comprise ultrasonic generator, concussion sonic generator, medical liquid container and control circuit, wherein, ultrasonic generator is connected with control circuit respectively with the concussion sonic generator, ultrasonic generator is connected with medical liquid container, and medical liquid container is provided with conduit and links to each other with concussion sonic generator conduit.
Described vibration sonic generator is the intrasonic speaker.
Be connected with the storage facilities that stores waveshape signal on the described vibration sonic generator.
During use, the sterile saline of specific concentrations is added in the medical liquid container, it and the conjoint outlet conduit that shakes sonic generator place patient's mouth, start working, ultrasonic generator scalable ultrasonic frequency, thereby control the atomizing particle size as required, concussion sonic generator scalable is selected concussion wave mode, frequency, thereby select the patient to feel comfortable parameter, and guarantee optimum efficiency.For more selection is provided, can external memory device, play the waveshape signal that is stored in the movable storage device.
The device that pulse oscillating of the present utility model atomizing induction of sputum device has atomizing and concussion function simultaneously sucks when saline hazes the patient, and per os gives the concussion of characteristic frequency, promote sputum to discharge, improve and induce success rate, shorten induction time, reduce dangerous.Have advantages such as simple in structure, that result of use is good.
Description of drawings
Fig. 1 is a structural representation of the present utility model.
Wherein, 1, control circuit; 2, ultrasonic generator; 3, medical liquid container; 4, conduit; 5, concussion sonic generator; 6, storage facilities.
The specific embodiment
Below in conjunction with accompanying drawing this utility model is further described.
A kind of pulse oscillating atomizing induction of sputum device, comprise ultrasonic generator 2, concussion sonic generator 5, medical liquid container 3 and control apparatus 1, as shown in Figure 1, wherein, ultrasonic generator 2 is connected with control circuit 1 respectively with concussion sonic generator 5, ultrasonic generator 2 is connected with medical liquid container 3, and medical liquid container 3 is provided with conduit 4.
Described vibration sonic generator 5 is a speaker.
Be connected with the storage facilities 6 that stores waveshape signal on the described vibration sonic generator 5.
During use, with the conduit on the medical liquid container 34, and the concussion sonic generator 5 place patient's mouth, open control circuit 1 is started working.Ultrasonic generator 2 scalable ultrasonic frequencies, thereby control the atomizing particle size as required, concussion sonic generator 5 scalable are selected the concussion wave mode, frequency, thereby select the patient to feel comfortable parameter, and guarantee optimum efficiency, for more selection is provided, external memory device 6 is play the waveshape signal that is stored in the movable storage device.
The above-mentioned content of not describing in detail is known technology of the prior art, does not repeat them here.

Claims (3)

1. pulse oscillating atomizing induction of sputum device, it is characterized in that: comprise ultrasonic generator, concussion sonic generator, medical liquid container and control circuit, wherein, ultrasonic generator is connected with control circuit respectively with the concussion sonic generator, ultrasonic generator is connected with medical liquid container, and medical liquid container is provided with conduit.
2. a kind of pulse oscillating atomizing induction of sputum device according to claim 1, it is characterized in that: described vibration sonic generator is the intrasonic speaker.
3. a kind of pulse oscillating atomizing induction of sputum device according to claim 1 is characterized in that: be connected with the storage facilities that stores waveshape signal on the described vibration sonic generator.
CN2011201711407U 2011-05-26 2011-05-26 Pulse oscillation and atomization sputum inducing device Expired - Fee Related CN202078618U (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103301537A (en) * 2013-06-08 2013-09-18 北京泰克美高新技术有限公司 Method and device for preparing 1 to 5micron aerosol salt for clearing away lung heat and eliminating phlegm
CN109045424A (en) * 2018-07-24 2018-12-21 上海常仁信息科技有限公司 A kind of intelligent atomization system based on robot
CN110812624A (en) * 2019-11-20 2020-02-21 湖南利德森医疗器械有限公司 Particle size sieving mechanism of atomizing machine
CN112294368A (en) * 2020-10-20 2021-02-02 温州市中心医院 New coronary pneumonia patient non-contact gathers appearance
CN112469380A (en) * 2018-06-14 2021-03-09 巴克科技私人有限公司 Vibroacoustic devices and methods for treating restrictive lung disease and improving pulmonary drainage function
CN113813478A (en) * 2021-10-11 2021-12-21 河南省儿童医院郑州儿童医院 Automatic control method and system for drug delivery of atomizer

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103301537A (en) * 2013-06-08 2013-09-18 北京泰克美高新技术有限公司 Method and device for preparing 1 to 5micron aerosol salt for clearing away lung heat and eliminating phlegm
CN112469380A (en) * 2018-06-14 2021-03-09 巴克科技私人有限公司 Vibroacoustic devices and methods for treating restrictive lung disease and improving pulmonary drainage function
CN112469380B (en) * 2018-06-14 2023-07-07 巴克科技私人有限公司 Vibro-acoustic devices and methods for treating restrictive lung disease and improving lung drainage function
CN109045424A (en) * 2018-07-24 2018-12-21 上海常仁信息科技有限公司 A kind of intelligent atomization system based on robot
CN110812624A (en) * 2019-11-20 2020-02-21 湖南利德森医疗器械有限公司 Particle size sieving mechanism of atomizing machine
CN112294368A (en) * 2020-10-20 2021-02-02 温州市中心医院 New coronary pneumonia patient non-contact gathers appearance
CN113813478A (en) * 2021-10-11 2021-12-21 河南省儿童医院郑州儿童医院 Automatic control method and system for drug delivery of atomizer

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