CN202033263U - Miniature detection cell for quartz crystal microbalance - Google Patents
Miniature detection cell for quartz crystal microbalance Download PDFInfo
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- CN202033263U CN202033263U CN2010206345525U CN201020634552U CN202033263U CN 202033263 U CN202033263 U CN 202033263U CN 2010206345525 U CN2010206345525 U CN 2010206345525U CN 201020634552 U CN201020634552 U CN 201020634552U CN 202033263 U CN202033263 U CN 202033263U
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- pool body
- crystal frame
- detection cell
- quartz wafer
- upper pool
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Abstract
The utility model relates to the design of a miniature detection cell for a quartz crystal microbalance in a liquid phase environment. The miniature detection cell for the quartz crystal microbalance comprises an upper cell body, a lower cell body and a crystal frame; the upper cell body and the lower cell body are connected by a fixing column, one or two pressure springs are arranged at one end or both ends of the fixing column, the upper cell body and the lower cell body are tightly fitted by a pressure spring, the crystal frame is arranged in a groove on the upper surface of the lower cell body, the crystal frame and the lower cell body are connected in a dismounting manner by the flexibility of the pressure spring. The miniature detection cell for the quartz crystal microbalance has simple structure, high integration degree, small dead volume, good leakage-proof performance and exquisite body form and is convenient to install and easy to carry.
Description
Technical field
The utility model relates to the minisize detection tank design of the QCM (Quartz Crystal Microbalance) in the liquid phase environment.
Background technology
QCM (Quartz Crystal Microbalance) (QCM) technology grows up gradually from discovery piezoelectric effects such as Curie in 1880, is applied at first in the gaseous environment, just begins to be applied in the liquid phase environment up to the eighties in 20th century.Based on the qcm sensor theory of quality and benifit, be under the thickness shear vibration mode, when the quartz wafer surface has material to change, cause the variation of crystal thickness, thereby cause that the wafer vibration frequency changes, can detect sensor surface nanogram level and change.QCM is the product that current microelectronics, biomedical engineering and materialogy etc. mutually combine and develop, as a kind of micro-mass sensor, it have easy to operate, use cost is low, need not mark, specificity is good, highly sensitive and respond advantage rapidly, be widely used in the fields such as chemistry, physics, biology, medical science and Surface Science, can be used for the constituent analysis of liquid and the measurement of little quality, the detection of film thickness etc.
Existing QCM (Quartz Crystal Microbalance) detection cell, or dead volume is excessive is unfavorable for the concentration of the intermolecular acting force of monitoring bio and biomolecule fast; Complex structure, installation steps are loaded down with trivial details; The bodily form is huge, is unfavorable for portable.
The utility model content
The purpose of this utility model is to provide a kind of minisize detection tank of QCM (Quartz Crystal Microbalance).
The technical solution adopted in the utility model is as follows:
A kind of minisize detection tank of QCM (Quartz Crystal Microbalance) comprises upper pool body, lower pool body, crystal frame.
The lower pool body upper surface is provided with a groove, and groove below is provided with outage, outage be positioned at quartz wafer resonator fixing on the crystal frame under.Crystal frame places in the groove, is fixed with the quartz wafer resonator on the crystal frame;
Lower surface in upper pool body is provided with annular groove, be placed with sealing O circle in the annular groove, upper pool body is fastened on the lower pool body top, sealing O circle be positioned at quartz wafer resonator fixing on the crystal frame directly over, be provided with feed pathway and liquid outlet channel in upper pool body, the outlet of feed pathway and the inlet of liquid outlet channel all are within the zone that annular groove draws a circle to approve; The sealing O circle of crystal frame and upper pool body constitutes airtight minisize detection tank cavity, and described detection cell cavity volume is at 10 μ L-60 μ L, and the leak resistance of minisize detection tank cavity is good;
Upper pool body links to each other by fixed leg with lower pool body, is provided with pressure spring in an end or two ends of fixed leg, and the force direction of pressure spring is perpendicular to the stationary plane between upper pool body and lower pool body, and upper pool body and lower pool body fit tightly together by pressure spring; When external force put between upper pool body and lower pool body, pressure spring compression, upper pool body and lower pool body were separated.
Crystal frame one end has the hole of an internal diameter less than the quartz wafer resonator, the quartz wafer resonator is fixed on the hole of crystal frame upper surface, the crystal frame lower surface leads to quartz wafer resonator electrode lead, and the crystal frame material is that pottery or teflon or transparent organic glass quartz wafer resonator comprise that unsupported AT-cuts quartz wafer matrix and is fixed in gold electrode on the quartz wafer.
Upper pool body, lower pool body material are transparent organic glass, thereby make the liquid flow condition of minisize detection tank cavity visual; The feed pathway of upper pool body and the axes intersect of liquid outlet channel are the 30-90 angle.Be equipped with the pipeline connector in the inlet of the feed pathway of upper pool body and the outlet of liquid outlet channel, its material is a teflon.The sunk screw of four symmetrical distributions is convenient to the fixing of this detection cell and outside installing plate.
Crystal frame and lower pool body are for removably connecting, it is convenient to install, when promptly only needing to put between upper pool body and lower pool body with external force, pressure spring compression, upper pool body and lower pool body are separated, insert crystal frame, then the airtight minisize detection tank cavity of sealing O circle formation inlayed of the lower surface of crystal frame and upper pool body; Dismounting is simple, crystal frame is a flat board, when only needing to put between upper pool body and lower pool body with external force, pressure spring compression, upper pool body and lower pool body are separated, taking off crystal frame gets final product, residual liquid in the minisize detection tank cavity from be positioned at the fixing quartz wafer resonator of crystal frame under outage discharge, whole process operation is convenient, and can guarantee the dry cleansing in the detection cell cavity.Described sealing O loop material is silicon rubber or fluororubber.
Need to prove simultaneously: though the quartz substrate vibrational stabilization, but when being used for QCM (Quartz Crystal Microbalance), Temperature Influence is still very important, and the instability of temperature will be to the interaction on fundamental frequency, measured object and QCM (Quartz Crystal Microbalance) surface, to the response of sample and recover all to have very big influence.Therefore, detection cell needs to work under steady temperature, the integrality of ability assurance device and result's reappearance.
This QCM (Quartz Crystal Microbalance) minisize detection tank can be formed the flow injection system that is applicable to on-line analysis with six-way injection valve, syringe pump or peristaltic pump.
QCM (Quartz Crystal Microbalance) minisize detection tank of the present utility model can be applicable to conventional no support quartz wafer resonator, handles with crystal oscillation unit, frequency measurement counting unit, Computer signal and forms high-sensitive liquid phase micro-mass sensor.
Advantage of the present utility model:
The minisize detection tank of QCM (Quartz Crystal Microbalance) of the present utility model compared with prior art, have simple in structure, the degree of integration height, dead volume is little, leak resistance is good, it is convenient to install, Controllable Temperature, easy to use, bodily form exquisiteness is easy to advantages such as portable.
Description of drawings
Fig. 1 is the minisize detection tank structural representation of QCM (Quartz Crystal Microbalance) of the present utility model.
Fig. 2 is the Flow Injection Analysis system stream synoptic diagram of QCM (Quartz Crystal Microbalance) of the present utility model.
Fig. 3 is the QCM (Quartz Crystal Microbalance) schematic diagram that is applicable in the liquid phase environment of the present utility model.
Embodiment
The present invention is further illustrated below in conjunction with accompanying drawing.
Case study on implementation
As shown in Figure 1 and Figure 2, a kind of minisize detection tank 12 of QCM (Quartz Crystal Microbalance) comprises upper pool body 3, lower pool body 6, crystal frame 5.
Lower pool body 6 upper surfaces are provided with a groove, and groove below is provided with outage 8, outage 8 be positioned at quartz wafer resonator fixing on the crystal frame 5 under.Crystal frame 5 places in the groove, is fixed with the quartz wafer resonator on the crystal frame 5.
Lower surface in upper pool body 3 is provided with annular groove 4, be placed with sealing O circle in the annular groove 4, upper pool body 3 is fastened on lower pool body 6 tops, sealing O circle be positioned at quartz wafer resonator fixing on the crystal frame 5 directly over, be provided with feed pathway 7 and liquid outlet channel 7 in upper pool body, the inlet of the outlet of feed pathway 7 and liquid outlet channel 7 all is within the zone that annular groove 4 drawn a circle to approve; Crystal frame 5 constitutes airtight minisize detection tank cavity with the sealing O circle of upper pool body 3, and described detection cell cavity volume is at 30 μ L, and described sealing O loop material is a silicon rubber.
Upper pool body 3 links to each other by fixed leg 1 with lower pool body 6, is provided with pressure spring 2 in an end or two ends of fixed leg 1, and upper pool body 3 fits tightly together by pressure spring 2 with lower pool body 6; When external force put on 6 of upper pool body 3 and lower pool bodies, pressure spring 2 compressions, upper pool body 3 were separated with lower pool body 6.
Upper pool body 3, lower pool body 6 materials are transparent organic glass, thereby make the liquid flow condition of minisize detection tank 12 cavitys visual; The feed pathway 7 of upper pool body 3 and the axes intersect of liquid outlet channel 7 are 60 degree angles.Be equipped with the pipeline connector in the inlet of the feed pathway 7 of upper pool body 3 and the outlet of liquid outlet channel 7, its material is a teflon.The sunk screw of four symmetrical distributions is convenient to the fixing of this detection cell 12 and outside installing plate.
Need to prove simultaneously: though the quartz substrate vibrational stabilization, but when being used for QCM (Quartz Crystal Microbalance), Temperature Influence is still very important, and the instability of temperature will be to the interaction on fundamental frequency, measured object and QCM (Quartz Crystal Microbalance) surface, to the response of sample and recover all to have very big influence.Therefore, detection cell needs to work under steady temperature, the integrality of ability assurance device and result's reappearance.Whole detection cell places thermostat, and temperature-control range is 30 ℃, temperature control precision+-0.2 degree.
As shown in Figure 2, this QCM (Quartz Crystal Microbalance) minisize detection tank 12 can be applicable to the flow injection system of on-line analysis with compositions such as six-way injection valve 9, syringe pumps 15.
The concrete operations flow process is as follows: under the baseline mode, syringe pump 15 with 30 μ L/min flows from liquid storage tank 14 with the moving phase sucking-off, continue to be transported to the feed pathway 7 of upper pool body 3 of the minisize detection tank 12 of QCM (Quartz Crystal Microbalance) through six-way injection valve 9, in enclosing the airtight minisize detection tank cavity of formation, the sealing O of crystal frame 5 and upper pool body 3 fully contacts with quartz-crystal resonator, from liquid outlet channel 7 discharged liquids, enter waste liquid pool 13 and reclaim;
Under the sampling pattern, from sample introduction needle 10 sample is injected in the quantitative ring of six-way injection valve 9, unnecessary sample flows out from waste liquid emptying pond 11;
Six-way injection valve 9 is switched to the sample introduction pattern, and the sample during moving phase will quantitatively be encircled is brought in the minisize detection tank 12 of QCM (Quartz Crystal Microbalance) and is detected, and flows into waste liquid pool 13 and reclaims.
As shown in Figure 3, QCM (Quartz Crystal Microbalance) minisize detection tank of the present utility model can be applicable to conventional no support quartz wafer resonator, handles with crystal oscillation unit, frequency measurement counting unit, Computer signal and forms high-sensitive liquid phase micro-mass sensor.
Claims (8)
1. the minisize detection tank of a QCM (Quartz Crystal Microbalance) is characterized in that: comprise upper pool body, lower pool body, crystal frame;
The lower pool body upper surface is provided with a groove, and the groove below is provided with outage, is fixed with the quartz wafer resonator on the crystal frame, and crystal frame places in the groove;
Lower surface in upper pool body is provided with annular groove, be placed with sealing O circle in the annular groove, upper pool body is fastened on the lower pool body top, sealing O circle be positioned at quartz wafer resonator fixing on the crystal frame directly over, be provided with feed pathway and liquid outlet channel in upper pool body, the outlet of feed pathway and the inlet of liquid outlet channel all are within the zone that annular groove draws a circle to approve; The sealing O circle of crystal frame and upper pool body constitutes airtight minisize detection tank cavity;
Upper pool body links to each other by fixed leg with lower pool body, is provided with pressure spring in an end or two ends of fixed leg, and upper pool body and lower pool body fit tightly together by pressure spring;
When external force put between upper pool body and lower pool body, pressure spring compression, upper pool body and lower pool body were separated.
2. detection cell as claimed in claim 1 is characterized in that: crystal frame and lower pool body are for removably connecting, and crystal frame is a flat board, and material is pottery or teflon or transparent organic glass; Crystal frame one end has the hole of an internal diameter less than the quartz wafer resonator, and the quartz wafer resonator is fixed on the hole of crystal frame upper surface, and the crystal frame lower surface leads to quartz wafer resonator electrode lead.
3. detection cell as claimed in claim 1 or 2 is characterized in that:
Described quartz wafer resonator comprises that unsupported AT-cuts quartz wafer matrix and is fixed in gold electrode on the quartz wafer.
4. detection cell as claimed in claim 1 is characterized in that:
Described upper pool body, lower pool body material are transparent organic glass; Described detection cell cavity volume is at 10 μ L-60 μ L.
5. detection cell as claimed in claim 1 is characterized in that:
The feed pathway of described upper pool body and the axes intersect of liquid outlet channel are 30-90 degree angle.
6. detection cell as claimed in claim 1 is characterized in that:
Be equipped with the pipeline connector in the inlet of the feed pathway of upper pool body and the outlet of liquid outlet channel.
7. detection cell as claimed in claim 1 is characterized in that:
Described outage be positioned on the crystal frame fixing quartz wafer resonator under.
8. detection cell as claimed in claim 1 is characterized in that:
Described sealing O loop material is silicon rubber or fluororubber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010206345525U CN202033263U (en) | 2010-11-30 | 2010-11-30 | Miniature detection cell for quartz crystal microbalance |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010206345525U CN202033263U (en) | 2010-11-30 | 2010-11-30 | Miniature detection cell for quartz crystal microbalance |
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| CN202033263U true CN202033263U (en) | 2011-11-09 |
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| CN2010206345525U Expired - Fee Related CN202033263U (en) | 2010-11-30 | 2010-11-30 | Miniature detection cell for quartz crystal microbalance |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103048210A (en) * | 2013-01-11 | 2013-04-17 | 东南大学 | Quartz crystal microbalance detecting device |
| CN103558110A (en) * | 2013-11-08 | 2014-02-05 | 崔学晨 | Quartz crystal sensor detection pond capable of preventing evaporation of liquid sample |
| CN106441524A (en) * | 2016-09-05 | 2017-02-22 | 清华大学深圳研究生院 | Wafer clamping device based on quartz crystal microbalance |
| CN110268236A (en) * | 2017-02-13 | 2019-09-20 | 高级波传感器有限责任公司 | Measuring unit |
| CN111043947A (en) * | 2019-12-30 | 2020-04-21 | 爱德森（厦门）电子有限公司 | Nuclear fuel assembly oxide film thickness eddy current testing device |
-
2010
- 2010-11-30 CN CN2010206345525U patent/CN202033263U/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103048210A (en) * | 2013-01-11 | 2013-04-17 | 东南大学 | Quartz crystal microbalance detecting device |
| CN103558110A (en) * | 2013-11-08 | 2014-02-05 | 崔学晨 | Quartz crystal sensor detection pond capable of preventing evaporation of liquid sample |
| CN106441524A (en) * | 2016-09-05 | 2017-02-22 | 清华大学深圳研究生院 | Wafer clamping device based on quartz crystal microbalance |
| CN106441524B (en) * | 2016-09-05 | 2019-04-16 | 清华大学深圳研究生院 | A kind of chip clamping device based on quartz crystal microbalance |
| CN110268236A (en) * | 2017-02-13 | 2019-09-20 | 高级波传感器有限责任公司 | Measuring unit |
| CN111043947A (en) * | 2019-12-30 | 2020-04-21 | 爱德森（厦门）电子有限公司 | Nuclear fuel assembly oxide film thickness eddy current testing device |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20111109 Termination date: 20141130 |
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| EXPY | Termination of patent right or utility model |