CN201939797U - Pipe-sealing device for intravenous indwelling needle - Google Patents
Pipe-sealing device for intravenous indwelling needle Download PDFInfo
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- CN201939797U CN201939797U CN2011200243170U CN201120024317U CN201939797U CN 201939797 U CN201939797 U CN 201939797U CN 2011200243170 U CN2011200243170 U CN 2011200243170U CN 201120024317 U CN201120024317 U CN 201120024317U CN 201939797 U CN201939797 U CN 201939797U
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Abstract
The utility model discloses a pipe-sealing device for an intravenous indwelling needle, which comprises a catheter, a transparent tee joint which is connected with the rear end of the catheter and an infusion joint which is connected with an infusion pipeline or a blood sampling pipeline, wherein a connecting part which is connected with a pipe-sealing injector is arranged at the middle section of an extension pipe, the pipe-sealing injector comprises a liquid storage pipe which is internally formed with a pipe cavity, a needle head part which is connected with the front end of a sealing pipe and a shell which is sleeved outside the liquid storage pipe and has sealed rear end, a protruded locking connecting joint is formed on the outer circumferential wall at the back end of the liquid storage pipe, a locking groove is formed on the inner circumferential wall at the front end of the shell, locking steps which are arranged with equal distance at intervals are formed on the inner circumferential wall of the shell, and a sealing plug which is connected with the back wall for the shell is arranged in the liquid storage pipe. With the adoption of the pipe-sealing device of the intravenous indwelling needle, pipe-sealing solutions with a same dosage are ensured to be pushed in each time and can be guaranteed to be filled in the pipe cavity of the indwelling needle. The pipe-sealing solution in the pipe-sealing injector selects a hirudin diluent, therefore, the pipe sealing device of the intravenous indwelling needle has good anticoagulant effect without influencing each index of a test of serum in blood.
Description
Technical field
This utility model belongs to technical field of medical instruments, particularly relates to a kind of venous detaining needle pipe sealing device.
Background technology
In recent years, develop rapidly along with medical science applied, the venous detaining needle that can alleviate patient's repeated localised puncture misery has been widely used among the patient of critical patient's rescue transfusion, intravenous hyperalimentation and vein batch applications antibiotic or other medicines.Venous detaining needle comprises puncture needle and conduit.After the puncture needle band conduit and penetrated patient's vein, extract puncture needle, conduit stays in the body, and the outer end connects infusion set or blood-taking device again.Venous detaining needle not only can be used for conventional venous transfusion, and can be used for repeatedly taking a blood sample discontinuously, and the misery of both having avoided repeated localised puncture to cause to the patient has been protected patient's vein again, can also improve nurse's work efficiency simultaneously.
Because the conduit of venous detaining needle needs the long period to stay in the human vein, after each transfusion is finished, cause tube chamber to stop up for preventing that blood from refluxing to condense, all need to carry out tube sealing.Usually use common syringe that tube-sealing solution is injected now and carry out tube sealing in the remaining needle tube chamber." practical Chinese medicine magazine " 2010 the 26th 1 phases of volume, put down in writing in " application of venous detaining needle and nursing " literary composition that Zhang Jianrong, the Hou Sifang in the hospital of traditional Chinese hospital, Ninghe County, Tianjin delivers, the tube sealing maneuver is an important ring, usually adopt slowly injection malleation sealed-tube method, be that the limit is slowly injected the limit and withdrawed from syringe needle, guarantee that needle tip keeps malleation, avoid backflow of blood to the blood vessel pin, cause the blood coagulation plugging.Above-mentioned blood vessel pin promptly refers to the conduit of remaining needle.But this use ordinary syringe is carried out pipe sealing method, and to be the nurse push the dosage of tube-sealing solution according to oneself experience decision, the dosage control that does not have strict standard, be difficult to guarantee all to be full of tube-sealing solution in each remaining needle tube chamber, especially catheter proximal end stretches into human body parts and is difficult to observe, if tube sealing does not thoroughly make backflow of blood to catheter proximal end, caused the blood coagulation plugging not to be found again, agglomerative clot is poured in the human vein by liquid when infusing once more, can cause the generation of thrombosis.
" Chinese general family medicine " March in 2010, the 8th volume the 3rd phase 395-396 page or leaf was put down in writing heparin sodium diluent and normal saline that present clinical main tube-sealing solution commonly used is a variable concentrations in " effect of two kinds of tube sealing methods of venous detaining needle relatively ".Normal saline can prevent blood coagulation with the effect of keeping extracellular osmotic pressure, blood volume and water-electrolyte balance, blood circulation, and little to vascular stimulation, its malleation tube sealing is safe and reliable, and clinical practice is extensive than the heparin in sealing method.But the normal saline tube sealing time is shorter, and conventional normal saline needs 3-5 hour tube sealing once, has increased nurse's workload, also bothers patient and has a rest.And the normal saline tube sealing easily causes phlebitis, because normal saline using dosage once probably needs 10-30ml, and generally can only tube sealing 3-5h, the nursing staff need be through normal saline flushing pipeline commonly used, flushing line need puncture as the calparine cap of sealing end cap, because calparine cap just is easy to by germ contamination through repeatedly puncturing, flows into human body by transfusion and cause symptoms such as phlebitis.Part calparine cap poor quality is arranged in addition, and repeatedly puncture is passed through infusion pipeline with trickle medical grade rubber chip easily, directly enters human vas and causes bigger harm.
Therefore, clinically also often the result of use heparin sodium diluent that is better than normal saline carry out tube sealing.Heparin is a kind of acid mucopolysaccharide, all has stronger anticoagulation when using in vivo and in vitro, the dilution back is widely used in clinical as the remaining needle tube-sealing solution, use a small amount of Calciparine/sodium salt water sealing (sealing water) pipe, phlebitic incidence rate is starkly lower than the normal saline tube sealing, and tube sealing effect retention time is longer than the normal saline tube sealing.But the heparin sodium tube sealing still has inevitable shortcoming, because heparin sodium has certain side effect to cause anticoagulant easily, easily causes bleeding, dosage is difficult for shortcomings such as grasp, so for have, the patient of disturbances of blood coagulation, Ying Shenyong in order to avoid increase the weight of the state of an illness, adverse consequences occurs.The remaining needle operation of can drawing blood in addition avoids the patient by the misery of repeated localised puncture, but uses normal saline and the equal effect of heparin sodium undesirable.
The concrete condition of normal saline and heparin sodium is as follows:
Normal saline does not have pipe sealing effect or effect extreme difference for some especial patient.For example: high blood viscosity denseness patient, hyperlipidemia patient because self-blood compares thickness, are easy to stop up the situation of remaining needle.In case the situation that remaining needle blocks appears, the remaining needle that the nurse can only more renew usually, and puncture again causes patient's the financial burden that repetition is painful and increase is new, also influences nurse's work efficiency simultaneously.And the normal saline using dosage is big, easy dilute blood, and every index is on the low side when causing blood test, and in addition because the characteristics of normal saline make too early the condensing of blood easily, blood preparation can't carry out clinical blood count after solidifying and going bad.
Though heparin sodium has anticoagulation preferably, can remedy normal saline is applied on the especial patient, but heparin sodium has shortcoming of itself and very important limitation, shortcoming is an anticoagulant, shortcoming such as easily cause bleeding, dosage is difficult for grasp, thus for have, the patient of disturbances of blood coagulation, Ying Shenyong, in order to avoid increase the weight of the state of an illness, adverse consequences appears; Limitation shows as the experiment that can't detect projects such as hematology's routine blood test, whole blood test, hemorheology test, pharmacokinetic experiment, serum biochemistry, blood bank's test, blood sugar test, erythrocyte sedimentation rate experiment with the blood that contains heparin sodium, so the blood drawing of need puncturing again from other positions of patient during the above-mentioned project of general need check.In sum, as seen some especial patient promptly is not suitable for normal saline, also is not suitable for the heparin sodium tube sealing, but tube-sealing solution hirudin diluent provided by the invention just can solve the disadvantage of above-mentioned two kinds of traditional tube-sealing solutions.
The People's Republic of China's " Chinese pharmacopoeia version in 2010, first record " Hirudo (HIRUDO) ", this product is the dry all of Hirudinidae animal whitmania Whitmania pigra Whitman, Hirudo Hirudo nipponica Whitman or Folium Salicis Babylonicae Hirudo Whitmania wranulata Whitman, summer, Qiu Erji catch, scald extremely with boiling water, dry or the low humidity drying.Concoct: Hirudo is cleaned, cutting, drying.Scald Hirudo: get water purification trematodiasis section, water to little with Pulvis Talci according to the method for scalding and heave.Function with cure mainly: removing blood stasis, removing blood stasis stimulates the menstrual flow.Be used for the blood stasis amenorrhea, injury from falling down.
Foreign medical science blood transfusion and 1993 the 16th volumes of blood fascicle the 6th phase record Chinese Academy of Medical Sciences Blood Research Institute, Guo Juan summary Wang Hebi examines and revises " progress of lepirudin 023 ludon " Haycraft and found in the Hementaria officianalis extract anticoagulant substances is arranged in 1884.At the end of the fifties, Markwardt isolates pure product first, called after hirudin (Hirudin), and know that it is the special inhibitor of thrombin, be a kind of ideal anticoagulant, antithrombotic preparation.Learn its structure and amino acid sequence the beginning of the eighties.Loaded down with trivial details because of the natural hirudin extraction step, and raise the Hirudo difficulty, the Hirudo source is deficient, is difficult to obtain the pure product of q.s, and research and clinical practice are restricted.In recent years, the development of technique for gene engineering has remedied this defective, utilize chemosynthesis, cDNA library, PCR method to obtain gene clone, express and obtain lepirudin 023 ludon, thereby pharmacology, pharmacodynamics and the toxicity etc. of hirudin have more in depth been studied, a large amount of zooperies and clinic trial have been accelerated hirudin and have been applied to clinical process.
The structure of hirudin: natural hirudin is not contain polysaccharide, by the single chain protein that 65 or 66 amino acid residues are formed, and molecular weight about 7,000, be rich in dicarboxylic amino acid, no Arg, Met and Trp, there are three intramolecular disulfide bonds to be positioned at peptide chain N-end, molecular configuration is played Stabilization; The C-end has more acidic amino acid residue, and a sulphation Tyr is arranged; The peptide chain middle part is by a special construction of being made up of Pro-Lys47-Pro, and it plays a part certain in hirudin and thrombin interaction.
In 11 kinds of variants of hirudin, only variant I, II and III have anticoagulating active.
So far, all can obtain active lepirudin 023 ludon through escherichia coli or Yeast system expression, and be desulfurization acidic group hirudin, promptly 63 Tyr do not have sulphation.Reorganization has isomorphic map mutually with natural prodcuts.Further can produce multiple variant.
Along with the molecular biology develop rapidly, external at present existing tens companies develop lepirudin 023 ludon and the plain preparation of functional Hirudo, a large number of experiments show that recombinant products is similar to natural prodcuts, are effective anticoagulant and antithrombotic preparation.
The clinical indication of lepirudin 023 ludon can be summarized as follows: 1) surgery anticoagulant; 2) internal medicine anticoagulant; 3) adjuvant of thrombolytic drug; 4) anticoagulant of angioplasty; 5) anticoagulant etc. in the hemodialysis.On the experimentation basis, carrying out clinical bulge test (as subacute and chronic DIC) at present.
The architectural feature of hirudin:
The single chain protein that natural hirudin is made up of 65 amino acid residues, the about 7000D of molecular weight is rich in dicarboxylic amino acid, no Arg, Met, Trp, peptide chain N-end has 3 intramolecular disulfide bond (Cys6-Cys14; Cys16-Cys28; Cys22-Cys39), molecular configuration is played Stabilization.The C-end has more acidic amino acid residue, and a sulphation Tyr is arranged, and is worked in the interaction of hirudin and thrombin by the special construction that a Pro-Lys47-Pro forms in the peptide chain middle part.
The chemical constitution of hirudin:
Hirudin on sale at present in market.
The utility model content
This utility model is to provide a kind of tube sealing effect that can guarantee in order to solve the variety of issue that exists in the prior art, can not need nurse's clinical manipulation easily to reach the pipe sealing purpose of malleation, need not the use amount that the nurse calculates tube-sealing solution, need not to screen patient's special circumstances selection tube-sealing solution, need not to prepare tube-sealing solution, need not the calparine cap of sterilizing before the use, can not enter blood, reduce the nurse job amount because of the calparine cap quality problems cause the medical grade rubber microgranule.Simple and safe operation can also reduce patient's phlebitis risk, reduces malpractice, reduce doctor-patient dispute, stop because the improper need of tube sealing are changed the expense of remaining needle again, also have tube sealing time length and can artificially control the tube sealing time, do not influence the venous detaining needle pipe sealing device of blood parameters again.
The technical scheme that this utility model is taked for the technical problem that exists in the solution known technology is:
Venous detaining needle pipe sealing device of the present utility model comprises by the puncture needle guiding penetrating intravenous conduit, is connected the transparent threeway and the infusion connector that is used to be connected infusion pipeline or blood sampling pipeline of the built-in isolating seal plug of rear end of conduit; One end of transparent threeway is connected with conduit, and an end is sealed by the isolating seal plug, and the 3rd end is connected with infusion connector by prolonging pipe, and infusion connector is by the sealing end caps; The stage casing that prolongs pipe is provided with the connecting portion that connects the tube sealing syringe, connecting portion and prolongation pipe internal communication; The tube sealing syringe comprises the inner liquid storage pipe that forms tube chamber, is connected the syringe needle part of sealed tube front end and is socketed in outside the liquid storage pipe and the shell of back-end closure; Be formed with the clamping line of projection on the periphery wall of liquid storage pipe rear end; Be formed with the draw-in groove that is connected with clamping line on the liquid storage pipe on the internal perisporium of shell front end, be formed with the card rank of same distance at interval on the shell internal perisporium; Be provided with the sealing-plug that is connected with housing back wall in the liquid storage pipe.Card rank on the described shell internal perisporium are anterior recessed, the inclined-plane that protrude at the rear portion.
The syringe needle part of described tube sealing syringe is connected with the connecting portion on prolonging pipe, and integrally formed with the perisporium of connecting portion; A side that perhaps prolongs the connecting portion on the pipe is formed with the insertion section of opening by the seal head sealing; The draw point of tube sealing syringe needle head part front end passes seal head and inserts in the connecting portion.
The tube-sealing solution of splendid attire is the hirudin diluent in the described liquid storage pipe.0.01mg/ml-40mg/ml for example.
Another kind of embodiment of the present utility model is: a kind of venous detaining needle pipe sealing device, comprise by the puncture needle guiding penetrating intravenous conduit, be connected the transparent threeway and the infusion connector that is used to be connected infusion pipeline or blood sampling pipeline of the built-in isolating seal plug of rear end of conduit; One end of transparent threeway is connected with conduit, and an end is sealed by the isolating seal plug, and the 3rd end is connected with infusion connector by prolonging pipe, and infusion connector is by the sealing end caps; The stage casing that prolongs pipe is provided with the connecting portion that connects the tube sealing syringe, connecting portion and prolongation pipe internal communication; The tube sealing syringe comprises the inner liquid storage pipe that forms tube chamber, is connected the syringe needle part of sealed tube front end and is connected the interior shell of liquid storage pipe; Be formed with the clamping line of projection on the periphery wall of shell front end; Be formed with the draw-in groove that is connected with clamping line on the shell on the internal perisporium of liquid storage pipe rear end, be formed with the card rank of same distance at interval on the liquid storage pipe internal perisporium; Be provided with the sealing-plug that is connected with housing back wall in the liquid storage pipe.Card rank on the described liquid storage pipe internal perisporium are anterior protrusion, the inclined-plane that the rear portion is recessed.
The syringe needle part of described tube sealing syringe is connected with the connecting portion on prolonging pipe, and integrally formed with the perisporium of connecting portion; A side that perhaps prolongs the connecting portion on the pipe is formed with the insertion section of opening by the seal head sealing; The draw point of tube sealing syringe needle head part front end passes seal head and inserts in the connecting portion.
The tube-sealing solution of splendid attire is the hirudin diluent in the described liquid storage pipe.
Described sleeve pipe adopts four polyvinyl fluoride materials to make, transparent threeway adopts medical material polythene material to make with the infusion connector that is used to be connected infusion pipeline or take a blood sample pipeline, the puncture needle material is that medical stainless steel is made, isolating seal plug, sealing-plug are that medical butyl rubber plug is made, the sealing end cap, draw-in groove, shell, card rank, clamping line, connector, liquid stopping block, hold needle handle, the puncture needle handle be that medical plastic is made, liquid storage pipe is made for the medical high polymer plastics.
Advantage and the good effect that the utlity model has are:
Venous detaining needle pipe sealing device of the present utility model, on venous detaining needle, connect the tube sealing syringe, and the interval same distance is provided with the card rank on the outer casing inner wall of tube sealing syringe, when promoting shell, when the clamping line on the liquid storage pipe runs into the card rank, be subjected to certain resistance and stop relative motion, at this moment, stop to promote shell, guarantee to push the tube-sealing solution of same dose at every turn.Distance between the card rank can guarantee that through calculating tube-sealing solution is full of the tube chamber of remaining needle, avoids backflow of blood and the blood coagulation plugging.Anticoagulant in the tube sealing syringe is selected the hirudin diluent for use, compares with other tube-sealing solution, and hirudin has good anticoagulation, and is because dosage is small, without any side effects to human body.Pass through the careful required tube-sealing solution of calculating in addition and can guarantee that the hirudin diluent is full of need tube sealing place accurately, easily reach the pipe sealing effect of malleation, when the blood sampling check, can not influence the detection of anticoagulin in the blood again, suit repeatedly be used for tube sealing in discontinuity transfusion and the blood collection procedure.And the clinical manipulation that does not need the nurse easily reaches the pipe sealing purpose of malleation, need not the use amount that the nurse calculates tube-sealing solution, need not to screen patient's special circumstances selection tube-sealing solution, need not to prepare tube-sealing solution, need not the calparine cap of sterilizing before the use, can not enter blood, reduce the nurse job amount because of the calparine cap quality problems cause the medical grade rubber microgranule.Simple and safe operation can also reduce patient's phlebitis risk, reduces malpractice, reduces doctor-patient dispute, stops because the improper need of tube sealing are changed the expense of remaining needle again, also has tube sealing time length and can artificially control the tube sealing time.
Description of drawings
Fig. 1 is the structural representation of the venous detaining needle pipe sealing device of this utility model first embodiment;
Fig. 2 is the structural representation of the venous detaining needle of this utility model second embodiment;
Fig. 3 is the structural representation of the tube sealing syringe of this utility model second embodiment.
Critical piece symbol description in the accompanying drawing:
1: conduit 2: transparent threeway 3: isolating seal plug
4: prolong pipe 5: liquid stopping block 6: infusion connector
7: the first sealing end caps sealing in 8: the second end cap 9: syringe needle part
10: sealing-plug 11: connecting portion 12: liquid storage pipe
13: draw-in groove 14: shell 15: the card rank
16: clamping line 17: puncture needle 18: the puncture needle handle
19: hold needle handle 20: tube sealing syringe 21: connector
22: insertion section 23: seal head
The specific embodiment
Followingly this utility model is described in detail with reference to drawings and Examples.Parts same as the prior art have used identical symbol in this utility model.
Fig. 1 is the structural representation of the venous detaining needle pipe sealing device of this utility model first embodiment.As shown in Figure 1, the venous detaining needle pipe sealing device of first embodiment comprises by the puncture needle guiding penetrating intravenous conduit 1, is connected the transparent threeway 2 and the infusion connector 6 that is used to be connected infusion pipeline or blood sampling pipeline of the built-in isolating seal plug 3 of conduit 1 rear end.
One end of transparent threeway 2 is connected with conduit 1, and an end is sealed by isolating seal plug 3, and the 3rd end is connected with infusion connector 6 by prolonging pipe 4.Prolong pipe 4 and be provided with liquid stopping block 5.Conduit 1 is socketed in outside the puncture needle 17, and stretch out from the front end of conduit 1 at the tip of puncture needle 17.The rear end of puncture needle 17 is provided with puncture needle handle 18, after conduit 1 enters vein for convenience, puncture needle 17 is extracted, and a side of puncture needle handle 18 is provided with holds needle handle 19.
The stage casing that prolongs pipe 4 is provided with the connecting portion 11 that connects tube sealing syringe 20, connecting portion 11 and prolongation pipe 4 internal communication.Tube sealing syringe 20 comprises the inner liquid storage pipe 12 that forms tube chamber, is connected the syringe needle part 9 of sealed tube 12 front ends and is socketed in outside the liquid storage pipe and the shell 14 of back-end closure.Be formed with the clamping line 16 of projection on the periphery wall of liquid storage pipe 12 rear ends.Be formed with the draw-in groove 13 that is connected with clamping line 16 on the liquid storage pipe 12 on the internal perisporium of shell 14 front ends, be formed with the card rank 15 of same distance at interval on shell 14 internal perisporiums.Card rank 15 are anterior recessed, the inclined-plane that protrude at the rear portion.The central authorities of shell 14 rear walls are formed with and extend to liquid storage pipe 12 intraluminal connectors 21, are fixedly connected on the front end of connector 21 with the sealing-plug 10 that liquid storage pipe 12 inwalls closely contact.
The syringe needle part 9 of tube sealing syringe 20 is connected with the connecting portion 11 that prolongation is managed on 4, and integrally formed with the perisporium of connecting portion 11.
The tube-sealing solution of splendid attire is the hirudin diluent in the above-mentioned liquid storage pipe.The concentration of hirudin is 0.01mg/ml in the hirudin diluent.Use according to the about 1ml-15ml of different needs at every turn.
Fig. 2 is the structural representation of the venous detaining needle of this utility model second embodiment; Fig. 3 is the structural representation of the tube sealing syringe of this utility model second embodiment.As shown in Figures 2 and 3, the second embodiment venous detaining needle pipe sealing device, comprise by puncture needle 17 guiding penetrating intravenous conduit 1, be connected the transparent threeway 2 and the infusion connector 6 that is used to be connected infusion pipeline or blood sampling pipeline of the built-in isolating seal plug 3 of conduit 1 rear end.
One end of transparent threeway 2 is connected with conduit 1, and an end is sealed by isolating seal plug 3, and the 3rd end is connected with infusion connector 6 by prolonging pipe 4.Prolong pipe 4 and be provided with liquid stopping block 5.Conduit 1 is socketed in outside the puncture needle 17, and stretch out from the front end of conduit 1 at the tip of puncture needle 17.The rear end of puncture needle 17 is provided with puncture needle handle 18, after conduit 1 enters vein for convenience, puncture needle 17 is extracted, and a side of puncture needle handle 18 is provided with holds needle handle 19.
The stage casing that prolongs pipe 4 is provided with the connecting portion 11 that connects tube sealing syringe 20, connecting portion 11 and prolongation pipe 4 internal communication.One side of connecting portion 11 is formed with the insertion section 22 of opening by seal head 23 sealings.Tube sealing syringe 20 comprises the inner liquid storage pipe 12 that forms tube chamber, is connected the syringe needle part 9 of sealed tube 12 front ends and is socketed in outside the liquid storage pipe 12 and the shell 14 of back-end closure.The draw point of tube sealing syringe needle head part 9 front ends passes seal head 23 and inserts in the connecting portion 11.Be formed with the clamping line 16 of projection on the periphery wall of liquid storage pipe 12 rear ends.Be formed with the draw-in groove 13 that is connected with clamping line 16 on the liquid storage pipe on the internal perisporium of shell front end, be formed with the card rank 15 of same distance at interval on the shell internal perisporium, card rank 15 be anterior recessed, the inclined-plane of rear portion protrusion.Be provided with the sealing-plug 10 that closely contacts with the liquid storage pipe inwall in the liquid storage pipe 12.The central authorities of shell 14 rear walls are formed with and extend to liquid storage pipe 12 intraluminal connectors 21; Sealing-plug 10 is fixedly connected on the front end of connector 21.
The tube-sealing solution of splendid attire is the hirudin diluent in the above-mentioned liquid storage pipe 12.The concentration of hirudin is 1mg/ml in the hirudin diluent.Use according to the about 1ml-15ml of different needs at every turn.
Each transfusion finishes or blood sampling when finishing, and tube sealing syringe 20 is inserted in connecting portions 11 tube chambers by seal head 23, push a certain amount of tube-sealing solution after, tube sealing syringe 20 extracted preserves after doing aseptic process.
Embodiment 3
The venous detaining needle pipe sealing device of this utility model the 3rd embodiment comprises by the puncture needle guiding penetrating intravenous conduit, is connected the transparent threeway and the infusion connector that is used to be connected infusion pipeline or blood sampling pipeline of the built-in isolating seal plug of rear end of conduit.
One end of transparent threeway is connected with conduit, and an end is sealed by the isolating seal plug, and the 3rd end is connected with infusion connector by prolonging pipe.Infusion connector can adopt single lumen catheter, also can adopt double lumen tube.If the employing single lumen catheter, the free end of single lumen catheter is by the sealing end caps; If the employing double lumen tube, two kinds of different medicines of infusion simultaneously, the two ends of double lumen tube are respectively by the first sealing end cap and the second sealing end caps.
The stage casing that prolongs pipe is provided with the connecting portion that connects the tube sealing syringe, connecting portion and prolongation pipe internal communication.The tube sealing syringe comprises the inner liquid storage pipe that forms tube chamber, is connected the syringe needle part of sealed tube front end and is connected the interior shell of liquid storage pipe.Be formed with the clamping line of projection on the periphery wall of shell front end.Be formed with the draw-in groove that is connected with clamping line on the shell on the internal perisporium of liquid storage pipe rear end, be formed with the card rank of same distance at interval on the liquid storage pipe internal perisporium, the card rank be anterior protrusion, the inclined-plane that the rear portion is recessed.Be provided with the sealing-plug that is connected with housing back wall in the liquid storage pipe.The central authorities of housing back wall are formed with and extend to the intraluminal connector of liquid storage pipe; Sealing-plug is fixedly connected on the front end of connector.
The syringe needle part of tube sealing syringe is connected with the connecting portion on prolonging pipe, and integrally formed with the perisporium of connecting portion.
The tube-sealing solution of splendid attire is the hirudin diluent in the above-mentioned liquid storage pipe.The concentration of hirudin is 35mg/ml in the hirudin diluent.Use according to the about 1ml-15ml of different needs at every turn.
Sleeve pipe is to adopt four polyvinyl fluoride materials to make, transparent threeway is to adopt medical material polythene material to make with the infusion connector that is used to be connected infusion pipeline or to take a blood sample pipeline, the puncture needle material is that medical stainless steel is made, isolating seal plug, sealing-plug are that medical butyl rubber plug is made, the sealing end cap, draw-in groove, shell, card rank, clamping line, connector, liquid stopping block, hold needle handle, the puncture needle handle be that medical plastic is made, liquid storage pipe is made for the medical high polymer plastics.
The venous detaining needle pipe sealing device of this utility model the 4th embodiment comprises by the puncture needle guiding penetrating intravenous conduit, is connected the transparent threeway and the infusion connector that is used to be connected infusion pipeline or blood sampling pipeline of the built-in isolating seal plug of rear end of conduit.
One end of transparent threeway is connected with conduit, and an end is sealed by the isolating seal plug, and the 3rd end is connected with infusion connector by prolonging pipe.Sheathed catheter is connected on outside the puncture needle, and stretch out from the front end of conduit at the tip of puncture needle.The rear end of puncture needle is provided with the puncture needle handle, after conduit enters vein for convenience, puncture needle is extracted, and a side of puncture needle handle is provided with holds needle handle.
Infusion connector can adopt single lumen catheter, also can adopt double lumen tube.If the employing single lumen catheter, the free end of single lumen catheter is by the sealing end caps; If the employing double lumen tube, two kinds of different medicines of infusion simultaneously, the two ends of double lumen tube are respectively by the first sealing end cap and the second sealing end caps.
The stage casing that prolongs pipe is provided with the connecting portion that connects the tube sealing syringe, connecting portion and prolongation pipe internal communication.One side of connecting portion is formed with the insertion section of opening by the seal head sealing.The tube sealing syringe comprises the inner liquid storage pipe that forms tube chamber, is connected the syringe needle part of sealed tube front end and is connected the interior shell of liquid storage pipe.The draw point of tube sealing syringe needle head part front end passes seal head and inserts in the connecting portion.Be formed with the clamping line of projection on the periphery wall of shell front end.Be formed with the draw-in groove that is connected with clamping line on the shell on the internal perisporium of liquid storage pipe rear end, be formed with the card rank of same distance at interval on the liquid storage pipe internal perisporium, the card rank be anterior protrusion, the inclined-plane that the rear portion is recessed.Be provided with the sealing-plug that is connected with housing back wall in the liquid storage pipe.The central authorities of housing back wall are formed with and extend to the intraluminal connector of liquid storage pipe; Sealing-plug is fixedly connected on the front end of connector.
The tube-sealing solution of splendid attire is the hirudin diluent in the above-mentioned liquid storage pipe.The concentration of hirudin is 40mg/ml in the hirudin diluent.Use according to the about 1ml-15ml of different needs at every turn.
Sleeve pipe is to adopt four polyvinyl fluoride materials to make, transparent threeway is to adopt medical material polythene material to make with the infusion connector that is used to be connected infusion pipeline or to take a blood sample pipeline, the puncture needle material is that medical stainless steel is made, isolating seal plug, sealing-plug are that medical butyl rubber plug is made, the sealing end cap, draw-in groove, shell, card rank, clamping line, connector, liquid stopping block, hold needle handle, the puncture needle handle be that medical plastic is made, liquid storage pipe is made for the medical high polymer plastics.
Each transfusion finishes or blood sampling when finishing, and the tube sealing syringe is inserted in the connecting portion tube chamber by seal head, push a certain amount of tube-sealing solution after, the tube sealing syringe extracted preserves after doing aseptic process.
According to first embodiment and second embodiment, specify and use tube sealing syringe of the present utility model to carry out pipe sealing method: when the tube sealing syringe was not used, the clamping line of liquid storage pipe was positioned at the draw-in groove of shell front end below.When using for the first time, promote the rear wall of shell forward with uniform power, sealing-plug moves forward, in the tube chamber of tube-sealing solution by syringe needle inflow remaining needle.The clamping line is deviate from draw-in groove, moves backward with respect to shell, when meeting first card rank, runs into certain resistance.Liquid storage pipe and shell stop relative motion, at this moment, stop thrust, and the tube-sealing solution in the liquid storage pipe is no longer flowed out by the syringe needle place, finishes tube sealing No. one time.Forward promote shell during tube sealing next time again, and the clamping line moves to second Ka Jiechu by first Ka Jiechu, finishes tube sealing again No. one time, by that analogy.Per two card rank spacing distances equate, guarantee to push the tube-sealing solution of same dose at every turn.Distance between the card rank can guarantee that through calculating tube-sealing solution is full of the tube chamber of remaining needle, avoids backflow of blood and the blood coagulation plugging.
The relation of hirudin and thrombin is as follows:
The first, lepirudin 023 ludon and α-thrombin with etc. mole non-covalent combine form stabilized complex (its dissociation constant is very little, 0.8 * 10
-10Mol or 2.0 * 10
-14Mol).The whole protease hydrolysis functions of thrombin this moment are closed, so hirudin can not only prevent fibrinogenic consolidation, and the hemostasis that can block catalyzed by thrombin is reacted, the platelet response that brings out such as activation and the thrombin of factor V, VIII and III, the thrombin that has prevented the activatory feedback of thrombinogen and caused generates, hirudin does not disturb the biosynthesis of thrombin simultaneously, and (AT-III) also do not have influence to Antithrombin III.
The second, oxidized when hirudin, disulfide bond, or its C-end is shown that by depsipeptides (the C-end reduces by 7 or 22 aminoacid then to the inhibition loss of activity 90% or 100% of thrombin) hirudin is a reversibility to the inhibitory action of thrombin.
Hirudin has following characteristics in actual applications:
The first, the agent of gene recombinaton hirudin anticoagulant does not contain heavy metal ion, does not have Sulfated pure biological preparation, and is noiseless to test item, is applicable to detections such as biochemistry, immunology, hematology.Also be applicable to unit blood specimen collections such as medical research mechanism, blood station, health and epidemic prevention.
The second, the Tyr peptide chain structure of hirudin can suppress the thrombin specificity, but this effect is reversible, and when the reaction of Tyr peptide chain warp depsipeptides, after the hirudin forfeiture suppressed activity, blood preparation also can be done hemagglutination test again.
The 3rd, haemachrome hematocrit and leukocyte etc. all there are not influence, can not only be used for the research of Physiological Experiment and clotting mechanism, and on clinical medicine, also can be used as the anticoagulant when transfusing blood.
The 4th, can reduce surface activity of blood platelet to platelet, anticoagulant reduces platelet adhesion.Hirudin can suppress the adhesive attraction of platelet to silication glass, and this is not direct interaction to hematoblastic effect, and it does not disturb hematoblastic function.
The 5th, the blood coagulation resisting function of hirudin in different animals and blood plasma its anticoagulation that confirms different with heparin, it does not rely on anticoagulant factor, does not disturb the detection of anticoagulant factor yet, is not subjected to influence of platelet CA++ (PF4) and rich histidine protein or the like yet.It is safe, the most effective antithrombase anticoagulant in the known anticoagulative substance in the present world.
Claims (8)
1. a venous detaining needle pipe sealing device comprises by the puncture needle guiding penetrating intravenous conduit (1), is connected the transparent threeway (2) and the infusion connector (6) that is used to be connected infusion pipeline or blood sampling pipeline of the built-in isolating seal plug (3) of rear end of conduit; One end of transparent threeway (2) is connected with conduit, and an end is sealed by isolating seal plug (3), and the 3rd end is connected with infusion connector (6) by prolonging pipe (4), and infusion connector is by the sealing end caps; It is characterized in that: the stage casing that prolongs pipe (4) is provided with the connecting portion (11) that connects tube sealing syringe (20), connecting portion (11) and prolongation pipe internal communication; Tube sealing syringe (20) comprises the inner liquid storage pipe (12) that forms tube chamber, is connected the syringe needle part (9) of sealed tube front end and is socketed in outside the liquid storage pipe and the shell (14) of back-end closure; Be formed with the clamping line (16) of projection on the periphery wall of liquid storage pipe (12) rear end; Be formed with the draw-in groove (13) that is connected with clamping line on the liquid storage pipe on the internal perisporium of shell (14) front end, be formed with the card rank (15) of same distance at interval on shell (14) internal perisporium; Be provided with the sealing-plug (10) that is connected with shell (14) rear wall in the liquid storage pipe (12).
2. a venous detaining needle pipe sealing device comprises by the puncture needle guiding penetrating intravenous conduit, is connected the transparent threeway and the infusion connector that is used to be connected infusion pipeline or blood sampling pipeline of the built-in isolating seal plug of rear end of conduit; One end of transparent threeway is connected with conduit, and an end is sealed by the isolating seal plug, and the 3rd end is connected with infusion connector by prolonging pipe, and infusion connector is by the sealing end caps; It is characterized in that: the stage casing that prolongs pipe is provided with the connecting portion that connects the tube sealing syringe, connecting portion and prolongation pipe internal communication; The tube sealing syringe comprises the inner liquid storage pipe that forms tube chamber, is connected the syringe needle part of sealed tube front end and is connected the interior shell of liquid storage pipe; Be formed with the clamping line of projection on the periphery wall of shell front end; Be formed with the draw-in groove that is connected with clamping line on the shell on the internal perisporium of liquid storage pipe rear end, be formed with the card rank of same distance at interval on the liquid storage pipe internal perisporium; Be provided with the sealing-plug that is connected with housing back wall in the liquid storage pipe.
3. according to claim 1 or the described venous detaining needle pipe sealing device of claim 2, it is characterized in that: the syringe needle of tube sealing syringe (20) part (9) is connected with connecting portion (11) on the prolongation pipe, and integrally formed with the perisporium of connecting portion (11).
4. according to claim 1 or the described venous detaining needle pipe sealing device of claim 2, it is characterized in that: a side that prolongs the connecting portion (11) on the pipe is formed with the insertion section (22) of opening by seal head (23) sealing; The draw point of tube sealing syringe needle head part (9) front end passes seal head (23) and inserts in the connecting portion (11).
5. venous detaining needle pipe sealing device according to claim 1 is characterized in that: the card rank on the shell internal perisporium are recessed for the front portion, the inclined-plane that protrude at the rear portion.
6. venous detaining needle pipe sealing device according to claim 2 is characterized in that: the inclined-plane that the rear portion is recessed is protruded for anterior in the card rank on the liquid storage pipe internal perisporium.
7. according to claim 1 or the described venous detaining needle pipe sealing device of claim 2, it is characterized in that: the tube-sealing solution of splendid attire is the hirudin diluent in the liquid storage pipe.
8. according to the hirudin anticoagulant blood tube sealing external member of claim 1 or the described venous detaining needle of claim 2, it is characterized in that: sleeve pipe (1) adopts four polyvinyl fluoride materials to make, transparent threeway (2) adopts medical material polythene material to make with the infusion connector (6) that is used to be connected infusion pipeline or to take a blood sample pipeline, puncture needle (17) material is that medical stainless steel is made, isolating seal plug (3), sealing-plug (10) is made for medical butyl rubber plug, sealing end cap (7) (8), draw-in groove (13), shell (14), card rank (15), clamping line (16), connector (21), liquid stopping block (5), hold needle handle (19), puncture needle handle (18) is made for medical plastic, and liquid storage pipe (12) is made for the medical high polymer plastics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011200243170U CN201939797U (en) | 2011-01-26 | 2011-01-26 | Pipe-sealing device for intravenous indwelling needle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011200243170U CN201939797U (en) | 2011-01-26 | 2011-01-26 | Pipe-sealing device for intravenous indwelling needle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201939797U true CN201939797U (en) | 2011-08-24 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011200243170U Expired - Fee Related CN201939797U (en) | 2011-01-26 | 2011-01-26 | Pipe-sealing device for intravenous indwelling needle |
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| Country | Link |
|---|---|
| CN (1) | CN201939797U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836479A (en) * | 2012-09-13 | 2012-12-26 | 苏州林华医疗器械有限公司 | Security-type venous indwelling needle |
| CN113633883A (en) * | 2021-07-23 | 2021-11-12 | 宁波市鄞州区第二医院医共体 | Disposable tube sealing liquid bag |
-
2011
- 2011-01-26 CN CN2011200243170U patent/CN201939797U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836479A (en) * | 2012-09-13 | 2012-12-26 | 苏州林华医疗器械有限公司 | Security-type venous indwelling needle |
| CN102836479B (en) * | 2012-09-13 | 2014-04-09 | 苏州林华医疗器械有限公司 | Security-type venous indwelling needle |
| CN113633883A (en) * | 2021-07-23 | 2021-11-12 | 宁波市鄞州区第二医院医共体 | Disposable tube sealing liquid bag |
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