CN201886855U - Magnetic circuit for nuclear magnetic resonance microscopic detection chip - Google Patents
Magnetic circuit for nuclear magnetic resonance microscopic detection chip Download PDFInfo
- Publication number
- CN201886855U CN201886855U CN2010206616052U CN201020661605U CN201886855U CN 201886855 U CN201886855 U CN 201886855U CN 2010206616052 U CN2010206616052 U CN 2010206616052U CN 201020661605 U CN201020661605 U CN 201020661605U CN 201886855 U CN201886855 U CN 201886855U
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- magnetic
- permanent magnet
- detection chip
- shimming plate
- magnetic resonance
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Abstract
The utility model relates to a magnetic circuit for a nuclear magnetic resonance microscopic detection chip, which comprises a first permanent magnet, a first shimming plate, a second shimming plate and a second permanent magnet in sequential arrangement, wherein a gap is formed between the first shimming plate and the second shimming plate to form a work air gap, and the first permanent magnet and the second permanent magnet have the same magnetic pole direction and are connected through a magnetizer. The magnetic circuit disclosed by the utility model has a tiny size and a low manufacture and maintenance cost, a magnetic field generated in a work region has a high magnetic field intensity and a good magnetic field uniformity, and the requirement of the atomic nuclear magnetic resonance microscopic detection chip can be perfectly met.
Description
Technical field
The utility model relates to a kind of magnetic resonance detection magnetic circuit, is specifically related to a kind of magnetic circuit that is used for the micro-detection chip of nulcear magnetic resonance (NMR).
Background technology
Atomic nucleus magnetic resonance detection method with compare based on detection techniques such as optics, electrochemistry, mass spectral analyses, owing to can discern the molecular structure of unknown particle, the new one-tenth metabolic process of observing biomone, particularly in the testing process to the non-destructive of biomone, just becoming the important technology that enables that biomone detects under the microfluidic environment, and this new branch of science of the micro-detection chip of atomic nucleus magnetic resonance that has been born thus.But traditional magnetic resonance detection equipment volume is huge, makes and the maintenance cost costliness, is difficult to mutually integratedly with the micro-fluidic doctor's of giving birth to chip, and its main cause is a kind of miniature magnetic circuit that is applicable to the micro-detection chip of atomic nucleus magnetic resonance of shortage.
The micro-detection chip of atomic nucleus magnetic resonance is owing to be specifically designed to the detection of micro-example, and its requirement to magnetic circuit is: 1. the field intensity of magnetic circuit wants the uniformity in height and magnetic field to get well; 2. the magnetic circuit volume and weight is less, to reduce the cost of manufacture of entire chip; 3. the magnetic structure opening is good, and the working region is easy to be complementary with other parts of chip and is convenient in the testing process manipulation to sample.
Though monolateral nulcear magnetic resonance (NMR) magnetic circuit greatly reduces than traditional its volume of nulcear magnetic resonance (NMR) magnetic circuit, but the magnetic field intensity that this kind magnetic circuit produces is less than normal, be mainly used in monolateral portable nuclear magnetic resonance instrument and be used for non-destructive and detect the large scale object, and too small field intensity is difficult to satisfy the high sensitivity requirement of chip to input when being applied to the micro-detection chip of atomic nucleus magnetic resonance.
The utility model content
The purpose of this utility model provides the magnetic circuit that is used for the micro-detection chip of nulcear magnetic resonance (NMR) of a kind of field intensity height, good uniformity.
Concrete scheme of the present utility model is: a kind of magnetic circuit that is used for the micro-detection chip of nulcear magnetic resonance (NMR), comprise first permanent magnet that from left to right is arranged in order, first shimming plate, second shimming plate, second permanent magnet, leave the gap between first shimming plate and second shimming plate and constitute working gas gap, first permanent magnet is identical with the pole orientation of second permanent magnet, and connects by magnetic conductor.
In order to improve the utilance of permanent magnet material, according to the needs of different operating environment, described first permanent magnet and second permanent magnet are cuboid, cylinder, square or cylindroid.
In order to improve the magnetic field intensity in the working gas gap, described first permanent magnet and second permanent magnet are made up of little permanent magnet splicing.
In order to increase uniform magnetic field scope in the working gas gap, and improve magnetic field intensity, the shape dissmilarity of first shimming plate and second shimming plate.Described first shimming plate is cylinder, cuboid, square or the cylindroid that indent forms recess, and second shimming plate is cylinder, cuboid, square or the cylindroid of regular shape; First shimming plate also can combine for cylinder, cuboid, square or cylindroid and annulus, straight-flanked ring, square loop or the vesica piscis by regular shape, and the cross sectional shape of ring can be rectangle, square, trapezoidal etc.The material of shimming plate can select for use electrical pure iron, permalloy, cold-rolled steel or other to have the material of high magnetic permeability.
In order to improve the magnetic field intensity in the working gas gap, described recess is provided with the inclination angle, and the size of angle is adjusted according to the size and the shape of working gas gap.
For the ease of installation and processing, improve its applicability, described magnetic conductor is made of three parts, first magnetic conductor that is connected with first permanent magnet outside magnetic pole, second magnetic conductor that is connected with the outside magnetic pole of second permanent magnet and the 3rd magnetic conductor that is connected first magnetic conductor and second magnetic conductor, the material of magnetic conductor can select for use electrical pure iron, permalloy, cold-rolled steel or other to have the material of high magnetic permeability.
The magnetic circuit that is used for the micro-detection chip of nulcear magnetic resonance (NMR) that the utility model provides, first permanent magnet and second permanent magnet produce magnetic field, and working gas gap is used to place sample, and first shimming plate and second shimming plate are used for strengthening working gas gap uniformity of magnetic field and intensity.The utility model magnetic circuit volume is small, and manufacturing and maintenance cost are cheap, and the field strength height, the uniformity of magnetic field that produce in the working region are good, can satisfy the demand of the micro-detection chip of atomic nucleus magnetic resonance preferably.
Description of drawings
Fig. 1 is a structural representation of the present utility model.
Fig. 2 is the square schematic diagram of y of the present utility model.
Fig. 3 is an x negative direction schematic diagram of the present utility model.
X-z coordinate plane internal magnetic field intensity contour map when Fig. 4 is magnetic circuit coordinate y=0 of the present utility model.
X-y coordinate plane internal magnetic field intensity contour map when Fig. 5 is magnetic circuit coordinate z=0 of the present utility model.
Embodiment
Below in conjunction with accompanying drawing the utility model is done further explanation.
The magnetic circuit that is used for the micro-detection chip of nulcear magnetic resonance (NMR) as Figure 1-3, comprise first permanent magnet 101 that is arranged in order, first shimming plate 201, second shimming plate 202, it is opposite with second permanent magnet, 102 left and right sides electromagnetic poles to leave gap formation working gas gap 401, the first permanent magnets 101 between second permanent magnet, 102, the first shimming plates 201 and second shimming plate 202, be respectively the S utmost point and the N utmost point, and connect by magnetic conductor.Wherein, first permanent magnet 101 and second permanent magnet 102 select for use neodymium iron boron to make rectangular structure, and the direction of arrow is the direction of magnetization among Fig. 1; First shimming plate 201 forms the rectangular thin plate of recess 301 for indent, there is the angle of inclination that size is θ in recess 301, second shimming plate 202 is the rectangular thin plate of regular shape, the optional electrical pure iron of using of the material of first shimming plate 201 and second shimming plate 202 also can select for use permalloy, cold-rolled steel or other to have the material of high magnetic permeability; Magnetic conductor is made of three parts, first magnetic conductor 501 that is connected with the S utmost point of first permanent magnet 101, second magnetic conductor 502 that is connected with the N utmost point of second permanent magnet 102 and the 3rd magnetic conductor 503 that is connected first magnetic conductor 501 and second magnetic conductor 502, the optional electrical pure iron of using of the material of magnetic conductor also can select permalloy, cold-rolled steel or other to have the material of high magnetic permeability.
As can be seen from the figure there were high strength uniform magnetic fields in a big way in x-y coordinate plane internal magnetic field intensity contour map when x-z coordinate plane internal magnetic field intensity contour map and coordinate z=0 when Fig. 4-5 was respectively the utility model magnetic circuit coordinate y=0 in the working gas gap 401.
The above only is a preferred implementation of the present utility model; be noted that for those skilled in the art; under the prerequisite that does not break away from the utility model principle; can also make some improvements and modifications, these improvements and modifications also should be considered as protection range of the present utility model.
Claims (6)
1. magnetic circuit that is used for the micro-detection chip of nulcear magnetic resonance (NMR), it is characterized in that: described magnetic circuit comprises first permanent magnet (101) that from left to right is arranged in order, first shimming plate (201), second shimming plate (202), second permanent magnet (102), leave the gap between first shimming plate (201) and second shimming plate (202) and constitute working gas gap (401), first permanent magnet (101) is identical with the pole orientation of second permanent magnet (102), and connects by magnetic conductor.
2. by the described magnetic circuit that is used for the micro-detection chip of nulcear magnetic resonance (NMR) of claim 1, it is characterized in that: described first permanent magnet (101) and second permanent magnet (102) are cuboid, cylinder, square or cylindroid.
3. by claim 1 or the 2 described magnetic circuits that are used for the micro-detection chip of nulcear magnetic resonance (NMR), it is characterized in that: described first permanent magnet (101) and second permanent magnet (102) are made up of little permanent magnet splicing.
4. by the described magnetic circuit that is used for the micro-detection chip of nulcear magnetic resonance (NMR) of claim 1, it is characterized in that: described first shimming plate (201) is cylinder, cuboid, square or the cylindroid of indent formation recess (301), and described second shimming plate (202) is cylinder, cuboid, square or the cylindroid of regular shape.
5. by the described magnetic circuit that is used for the micro-detection chip of nulcear magnetic resonance (NMR) of claim 4, it is characterized in that: described recess (301) is provided with the inclination angle.
6. by the described magnetic circuit that is used for the micro-detection chip of nulcear magnetic resonance (NMR) of claim 1, it is characterized in that: described magnetic conductor is made of three parts, first magnetic conductor (501) that is connected with first permanent magnet (101) outside magnetic pole is with second permanent magnet (102) outside magnetic pole second magnetic conductor (502) that is connected and the 3rd magnetic conductor (503) that is connected first magnetic conductor (501) and second magnetic conductor (502).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010206616052U CN201886855U (en) | 2010-12-15 | 2010-12-15 | Magnetic circuit for nuclear magnetic resonance microscopic detection chip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010206616052U CN201886855U (en) | 2010-12-15 | 2010-12-15 | Magnetic circuit for nuclear magnetic resonance microscopic detection chip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201886855U true CN201886855U (en) | 2011-06-29 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010206616052U Expired - Lifetime CN201886855U (en) | 2010-12-15 | 2010-12-15 | Magnetic circuit for nuclear magnetic resonance microscopic detection chip |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201886855U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102110513A (en) * | 2010-12-15 | 2011-06-29 | 东南大学 | Magnetic circuit for detecting chip through nuclear magnetic resonance microscope |
| CN103576113A (en) * | 2012-07-26 | 2014-02-12 | 西门子(深圳)磁共振有限公司 | Superconducting magnet and shimming device and method thereof |
-
2010
- 2010-12-15 CN CN2010206616052U patent/CN201886855U/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102110513A (en) * | 2010-12-15 | 2011-06-29 | 东南大学 | Magnetic circuit for detecting chip through nuclear magnetic resonance microscope |
| CN102110513B (en) * | 2010-12-15 | 2013-07-31 | 东南大学 | Magnetic circuit for detecting chip through nuclear magnetic resonance microscope |
| CN103576113A (en) * | 2012-07-26 | 2014-02-12 | 西门子(深圳)磁共振有限公司 | Superconducting magnet and shimming device and method thereof |
| CN103576113B (en) * | 2012-07-26 | 2016-06-08 | 西门子(深圳)磁共振有限公司 | A kind of superconducting magnet and shimming device thereof and method for shimming |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20110629 Effective date of abandoning: 20130731 |
|
| RGAV | Abandon patent right to avoid regrant |