CN201698633U - Anterior ocular segment irrigation device - Google Patents
Anterior ocular segment irrigation device Download PDFInfo
- Publication number
- CN201698633U CN201698633U CN 200920276178 CN200920276178U CN201698633U CN 201698633 U CN201698633 U CN 201698633U CN 200920276178 CN200920276178 CN 200920276178 CN 200920276178 U CN200920276178 U CN 200920276178U CN 201698633 U CN201698633 U CN 201698633U
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- anterior ocular
- ocular segment
- groove
- main body
- casting according
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Abstract
The utility model provides an anterior ocular segment irrigation device, which comprises a main body adopting a square table model structure, and a groove is formed in the middle of the main body. The anterior ocular segment irrigation device is characterized in that at least three holes are formed at the bottom of the groove; the holes are connected with one end of a tube in certain rigidity correspondingly; a plastic cap installed at the other end of the tube can be opened and closed; a plurality of long screws are distributed around the groove; moreover, when an anterior ocular segment tissue slide is placed on the groove, a gasket and a fixing cap are covered above the groove, nuts are screwed to the screws so as to fix the gasket, and the fixing cap and the anterior ocular segment tissue slide to the main body, so that the interior space of the groove becomes airtight.
Description
Technical field
The utility model relates to a kind of with the anterior ocular segment device for casting of eyeball as research object, gives and perfusion by the eyeball tissue in being fixed in this device (anterior ocular segment tissue), simulates the physiological and pathological state, measures index of correlation.
Background technology
In ophthalmologic research, we wish to know eyeball pressure inside and medicine are how to pass through the eyeball metabolism.In clinical position, the blood pressure that we measure not is the real instant pressure of internal blood vessel, but connects measurement by tie up pressurization interband on arm, and real blood pressure is to be needled into blood vessel with one, connect a pressure transducer, the numerical value of reading is just accurate.Certainly, in clinical position, we do not need to do like this, only just do like this when scientific research.In like manner, clinically, we measure the eyeball pressure inside indirectly by tonometer, but in scientific research, and we need get the in-vitro eyeball of animal, thrust a pin, after connect pressure transducer, be only the inner real pressure of eyeball like this.If the material that we will get in the eyes performs an analysis, also to take a sample by this root pin.But, because the eyeball that exsomatizes has not had normal metabolic, will be flat fall through such operation, test just can't go on, so we just need irritate liquid inside, we just need the device that eyeball is fixed so, can repeatedly take a sample, gaging pressure repeatedly, continuous irrigation liquid.
In present research, we take off whole eyeball on one's body from animal, are fixed on the estrade, insert a very thin pipe below and keep the shape of eyeball to irritate liquid inside, study the effect of medicine if desired, also can be medicine from irritating here.A pin is thrust in the side, connects sensor or sampler, carries out the work of gaging pressure or sampling.
Prior art has the following disadvantages:
(1) the fixing difficulty of whole eyeball.Because individual difference, the eyeball difference in size of homozoic Different Individual is very big, and fixator needs a bigger adjustable extent, guarantees obturation effect again, and is so very difficult.
(2) tissue is perishable.Whole eyeball relates to will keep the multiple tissue of intraocular, and the time-to-live after various tissues exsomatize is different, and several hours of having are just rotten, and what have can survive a few days in nutrient solution.But the whole eyeball device is owing to kept whole tissues, and its pot-life has been limited test period by the time limit decision of tissue the most apt to deteriorate.Because the circulation of eyes the inside is not to pass through all structures to the front from behind, so do not need to keep all parts.
(3) obturation effect is poor.Because puncture needle is directly to insert eyeball, there is not other airtight and fixation around the point of puncture, leak easily or slippage, cause test failure.
The utility model content
The purpose of this utility model provides a kind of anterior ocular segment device for casting, this device can keep the institutional framework with circular correlation, and the reservation area of tissue can suitably be adjusted to guarantee consistent with this device, and puncture needle enters from this device, no longer directly penetrate eyeball, guaranteed leakproofness.Remove perishable structural constituent, prolonged test period.
To achieve these goals, the utility model provides a kind of anterior ocular segment device for casting, this device comprises main body, this main body is square mesa structure, there is a groove centre of described main body, it is characterized in that: the bottom of described groove is provided with at least three holes, described hole correspondingly is connected with an end of the pipe of certain degree of hardness, the other end of described pipe is equipped with plastic cap, this plastic cap can be opened or close, many long screws distribute around the described groove, when the anterior ocular segment tissue places on the described groove, above described groove, cover packing ring and locking cap, and by with nut screwing clamping to screw and with packing ring, locking cap and anterior ocular segment tissue are fixed on the described main body, thereby make the inner space of described groove be in air-tight state.
This device can the metabolism of altitude simulation intraocular physiological status, be easy to the influence that in device interpolation medicine is simulated disease and medicine, make real-time detection intraocular pressure and other technical indicators become possibility.This device is easy to preparation, stable performance, and repeatable strong, the data that obtained have higher researching value.
Description of drawings
Fig. 1 shows the vertical view of anterior ocular segment device for casting of the present utility model;
Fig. 2 shows the front view of anterior ocular segment device for casting of the present utility model.
Embodiment
The structure of anterior ocular segment device for casting of the present utility model as depicted in figs. 1 and 2.This device main body is made by certain thickness polymethyl acrylate, for the square mesa structure of class, as operating platform 1.There is a groove 2 centre of main body, and groove 2 has certain degree of depth, and the degree of depth of groove 2 is reference with the thickness of eye lens, and groove 2 is formed by machined into, the anterior ocular segment tissue of the diameter of groove 2 and test usefulness big or small roughly the same.The edge of groove 2 exceeds operating platform 1 a little, and certain width is arranged, and fixes with the tissue of convenient different sizes.
Three holes are arranged at the bottom of groove 2, connect the pipe 5 that three silicone tubes that certain degree of hardness arranged are made, the other end of pipe 5 is the plastic cap of the outlet of formation pipe 5, external plastic cap, this plastic cap can close and open, and these three pipes 5 are respectively applied for and connect pressoreceptor, injection perfusion liquid and dosing and exhaust.This pipe 5 can adopt any way (as bonding) to be fixed to the bottom of groove.
The screw 4 of distribute on every side many long (being preferably four) of groove 2, table top is fixed in bonding mode in the lower end of screw 4, last end dissociative.In experiment, the anterior ocular segment tissue is placed on the groove 2, cover packing ring and the preferred locking cap of making by polymethyl acrylate 3 preferably made above by silica gel or silicon gel, with nut locking cap 3, packing ring, anterior ocular segment tissue and agent structure are fixed.
Because it is harder to constitute the material (polymethyl acrylate) of locking cap 3, in order to increase leakproofness, installs removable silicone gasket additional below locking cap 3.
In working order down, at first the anterior ocular segment tissue is cut into suitable size, places on the groove 2 of device, guaranteeing has certain scleral tissue to be covered on the edge of groove 2, airtight to guarantee; Silicone gasket and locking cap 3 screw screw 4 on the pad; Inject perfusion liquid in an intrusion pipe, perfusion liquid can enter in the groove 2, because groove 2 has been in air-tight state, has a spot of air when tissue is installed and remains in the groove 2; Open exhaust/chemical feed pipe, the air of remover inherence contacts tissue fully with perfusion liquid; The leakproofness of check system; Utilize the 3rd pipe 5, connect pressoreceptor or other instruments, or utilize exhaust/medicine-pouring pipe application of sample, begin test.
Anterior ocular segment device for casting of the present utility model also can be made by other pmma materials.The bottom of groove 2 can be provided with four holes at most.Around the platform 1 of main body, also can install " dykes and dams " additional.In addition, this device also can be used for collecting the liquid that goes out by the intraocular metabolism.
Adopt said structure, can make all good being fixed in the test unit of energy of tissue of different sizes to a certain degree (because there is certain width at the edge of groove, can cover many slightly or few slightly tissue, owing to be not sharp property edge, can not cause cutting simultaneously) tissue.This device is organized be in good air-tight state within a certain period of time.The pipe that connects intraocular structure enters the damage of having avoided direct puncture tissue to cause by the device bottom.This device kept the approach of intraocular metabolism, and it is perishable and do not participate in the part of metabolism to have removed the eyeball rear portion, has accomplished farthest to remain with tissue.
Claims (10)
1. anterior ocular segment device for casting, this device comprises main body, described main body is as operating platform, there is a groove centre of described main body, it is characterized in that: the bottom of described groove is provided with at least three holes, described hole correspondingly is connected with an end of pipe, the other end of described pipe is equipped with plastic cap, this plastic cap can be opened or close, many long screws distribute around the described groove, the anterior ocular segment tissue places on the described groove, above described groove, cover packing ring and locking cap, and by with nut screwing clamping to screw and with packing ring, locking cap and anterior ocular segment tissue are fixed on the described main body, thereby make the inner space of described groove be in air-tight state.
2. anterior ocular segment device for casting according to claim 1, the diameter of wherein said groove with will be placed on the big or small roughly the same of anterior ocular segment tissue in this groove.
3. anterior ocular segment device for casting according to claim 1, the edge of wherein said groove exceeds described operating platform a little, and the tissue that the width at the edge of described groove is convenient to different sizes are fixed.
4. anterior ocular segment device for casting according to claim 1, the bottom of wherein said groove are provided with four holes.
5. anterior ocular segment device for casting according to claim 1, wherein said packing ring is made by silica gel or silicon gel.
6. anterior ocular segment device for casting according to claim 1, wherein said main body and described locking cap are made by polymethyl acrylate.
7. add removable silicone gasket below the anterior ocular segment device for casting according to claim 5, wherein said locking cap.
8. anterior ocular segment device for casting according to claim 1, wherein said main body is made by pmma material.
9. anterior ocular segment device for casting according to claim 1, wherein said pipe is made by silicone tube.
10. anterior ocular segment device for casting according to claim 1 wherein is provided with dykes and dams around described main body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200920276178 CN201698633U (en) | 2009-12-09 | 2009-12-09 | Anterior ocular segment irrigation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200920276178 CN201698633U (en) | 2009-12-09 | 2009-12-09 | Anterior ocular segment irrigation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201698633U true CN201698633U (en) | 2011-01-05 |
Family
ID=43399879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200920276178 Expired - Fee Related CN201698633U (en) | 2009-12-09 | 2009-12-09 | Anterior ocular segment irrigation device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201698633U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103834562A (en) * | 2014-01-07 | 2014-06-04 | 中国人民解放军第三军医大学第二附属医院 | In-vitro ocular anterior segment tissue culture device |
| CN103903503A (en) * | 2014-03-24 | 2014-07-02 | 首都医科大学 | Anterior segment aqueous fluid circulating flow simulation device |
| CN114608746A (en) * | 2022-03-08 | 2022-06-10 | 三门峡市眼科医院 | In-vitro pig anterior ocular segment perfusion and culture model and application thereof |
-
2009
- 2009-12-09 CN CN 200920276178 patent/CN201698633U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103834562A (en) * | 2014-01-07 | 2014-06-04 | 中国人民解放军第三军医大学第二附属医院 | In-vitro ocular anterior segment tissue culture device |
| CN103834562B (en) * | 2014-01-07 | 2016-03-23 | 中国人民解放军第三军医大学第二附属医院 | In vitro anterior ocular segment tissue culture device |
| CN103903503A (en) * | 2014-03-24 | 2014-07-02 | 首都医科大学 | Anterior segment aqueous fluid circulating flow simulation device |
| CN103903503B (en) * | 2014-03-24 | 2020-01-14 | 首都医科大学 | Anterior segment aqueous humor circulation simulation device |
| CN114608746A (en) * | 2022-03-08 | 2022-06-10 | 三门峡市眼科医院 | In-vitro pig anterior ocular segment perfusion and culture model and application thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110105 Termination date: 20131209 |