CN201697890U - Urine sugar test strip - Google Patents

Urine sugar test strip Download PDF

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Publication number
CN201697890U
CN201697890U CN2010202235846U CN201020223584U CN201697890U CN 201697890 U CN201697890 U CN 201697890U CN 2010202235846 U CN2010202235846 U CN 2010202235846U CN 201020223584 U CN201020223584 U CN 201020223584U CN 201697890 U CN201697890 U CN 201697890U
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CN
China
Prior art keywords
electrode
glucose
thief hatch
siphon
dividing plate
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Expired - Lifetime
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CN2010202235846U
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Chinese (zh)
Inventor
梁明龙
姚崇德
刘勤
章艳艳
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GUILIN ZHONGHUI TECHNOLOGY DEVELOPMENT Co Ltd
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GUILIN ZHONGHUI TECHNOLOGY DEVELOPMENT Co Ltd
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Abstract

The utility model discloses a urine sugar test strip, which comprises a substrate, wherein the substrate is provided with three strip-shaped electric-conductive electrodes: an anode electrode, a cathode electrode and a short circuit electrode, the short circuit electrode is connected with the anode electrode or the cathode electrode, the upper part of the electric-conductive electrode is provided with an insulation isolation layer so that conduction part of the electrode on the front end of the electric-conductive electrode is exposed outside, the insulation isolation layer is provided with a response window, the span of the response window simultaneously covers the cathode electrode and the anode electrode, the interior of the response window is pasted with an enzyme reaction film, a bonding partition board is arranged above the insulation isolation layer, the partition board is machined with a sampling port and a siphon sample guide slot which are communicated, the sampling port is arranged on one end of the conduction part of the electrode, which is far away from the substrate, and the position of the siphon sample guide slot corresponds to the position of the response window above the insulation isolation layer. Compared with the prior art, the utility model has simple operation, high sensitivity, and faster, correct and reliable test result.

Description

A kind of glucose in urine test-strips
Technical field
The utility model relates to a kind of external diagnosis reagent, is specifically related to a kind of and the matching used glucose in urine test-strips of glucose in urine tester.
Background technology
In order to control metabolic situation,, need the concentration of glucose in the control volume circulation termly particularly for diabetes cases.This is necessary for the type i diabetes patient who wants insulin injection not only, also is that so the latter accounts for 85% of this glycometabolism disease for the type ii diabetes patient.According to expectation, to world diabetic number in 2010 will reach 200,012,100 (Hauner, H; DtschMed Wochenschr (German medical science weekly) 1998; 123; 777-82; Pharmaco Economlcs (medication economics) 1995; 8 (Suppl, I) 28-71; ).
In view of the high incidence of diabetes, conventional needs and the hope that blood glucose measurement that skin penetrating carries out can not satisfy regular metabolism control of passing through is only arranged.This needs the patient to overcome the mental handicape of stabbing skin before each the measurement.For Most patients, do not need measuring blood, and as long as the concentration of glucose in the control urine.If surpassed the threshold value of kidney by metabolic stimulation, just cause the glucose outside the physiological requirements to be discharged through kidney as glucose in urine, the glucose in urine just is presented as can detected concentration.Therefore, although blood sugar test is quite universal, glucose in urine detects as a kind of very easy noninvasive detection method of operation of using, and still is subjected to considerable part diabetic's welcome deeply.
A kind of characteristic of measuring the method for glucose in urine based on glucose makes light polarization and dextrorotation.Said polarization photometer has just utilized this specific character, and wherein light is estimate (Poege, A.W.Z med.Labortechnik (medical experimental chamber diagnostic techniques) 17 (1976) 59-79) of actual concentration of glucose from the angle of plane of polarization deflection.
Usually adopt glucose in urine to detect test paper for the screening family of prevention usefulness and the method for the glucose content in the human urine, this class test paper majority is the color reaction that produces the glucose compliance on the zymochemistry basis.The shortcoming of these test strips is poor accuracy, the half-quantitative detection that can only be used for glucose in urine, and remolding sensitivity is lower, generally all reach 50mg/dl at glucose in urine content, even 100mg/dl just can demonstrate the positive, also must be with accurate judged result of strict control time of clock during test, thus measurement result is very unreliable.And have only the people that can differentiate color to adopt, and among diabetic's, particularly type ii diabetes the gerontal patient, considerable people is a colour blindness, it is inaccurate to debate look at least.
Above-mentioned polarization photometer is the clinical chemistry that is used for that is equipped with as laboratory equipment, and the glucose of expressing reliably in the daily metabolism control in the urine exists and the conventional method of concentration and Tes-Tape is not suitable for being used as.Therefore research and development more and more concentrates on enzymatic-electrochemical measuring device and the application aspect glucose assays thereof.2008, a kind of biology sensor glucose in urine tester that can carry out detection by quantitative to glucose in urine has been released in a company's development of Japan, but because it adopts the fixation of sensor detection head, cost an arm and a leg, the use cost height, and detection head is repeatedly to use repeatedly, needs to clean, and also can face some problems of sterilization aspect.
The utility model content
The technical problems to be solved in the utility model is at the deficiencies in the prior art, and a kind of glucose in urine test-strips of employing biosensor technology highly sensitive, easy and simple to handle, with low cost is provided.This glucose in urine test-strips and supporting glucose in urine tester use, and can not only fast quantification detect the glucose content in the urine, and detectable glucose in urine content are low to moderate 2mg/dl.
For solving the problems of the technologies described above, the utility model by the following technical solutions:
A kind of glucose in urine test-strips, comprise substrate, substrate is provided with three strip conductive electrodes, be respectively anode electrode, cathode electrode and short-circuiting electrode, short-circuiting electrode wherein and anode electrode or cathode electrode join, part is provided with dielectric isolation layer so that the electrode conducting part of conductive electrode front end is exposed outside on conductive electrode, offer the reaction window on the described dielectric isolation layer, the span of this reaction window is while covered cathode electrode and anode electrode, is pasted with the enzyme reaction film in the reaction window; On described dielectric isolation layer, be provided with a bonding dividing plate, offer the thief hatch, the siphon that are interconnected on this dividing plate and lead the sample groove, wherein thief hatch is arranged at the end away from substrate top electrode conducting part, siphon lead the sample groove to offer on position and the dielectric isolation layer reaction position of window corresponding.
For making whole test-strips more attractive in appearance, the operation of also being more convenient for simultaneously can be pasted a surface encapsulation plate on described bonding dividing plate, leads the gas port that the sample groove communicates but must offer on bonding dividing plate with siphon this moment, and this gas port runs through the narrow end of bonding dividing plate; Or gas port is offered in the corresponding position of leading the sample groove with siphon on described surface encapsulation plate.
Described reaction window is the square groove that be arranged in parallel with dielectric isolation layer.
Be simplified design, described siphon can be led the sample groove and extend until the termination of bonding dividing plate, thereby form the thief hatch on this bonding dividing plate in this end towards direction away from substrate top electrode conducting part.When product is such design, when testing, preferably adopt the mode that test-strips is immersed in the urine sample to take a sample.
Having in this glucose in urine test-strips under the situation of surface encapsulation plate, generally is that described thief hatch is opened in the end that the sample groove is led in siphon, and gas port is opened in the front end that the sample groove is led in siphon.Offer and the corresponding thief hatch of thief hatch shape cave with corresponding position, thief hatch position this moment on described surface encapsulation plate, so that the splashing into of urine sample.Can certainly on substrate, offer and the corresponding thief hatch of thief hatch shape cave with corresponding position, thief hatch position.
Described thief hatch can be designed to difformity as required, is generally circle or semicircle.
Compared with prior art, the utility model glucose in urine test-strips has realized the high sensitivity quantitation detection when keeping traditional Tes-Tape not have wound detection advantage.The supporting use of glucose in urine tester of this product and applicant's development, easy and simple to handle, the test effect is quicker, accurate, reliable.
Description of drawings
Fig. 1 is the structural representation of first embodiment of the present utility model;
Fig. 2 is the STRUCTURE DECOMPOSITION figure of embodiment shown in Figure 1;
Fig. 3 is the structural representation of this second novel embodiment;
Fig. 4 is the structural representation of this 3rd novel embodiment;
Fig. 5 is the structural representation of this 4th novel embodiment;
Fig. 6 is the STRUCTURE DECOMPOSITION figure of embodiment shown in Figure 5;
Fig. 7 is the structural representation of this 5th novel embodiment;
Fig. 8 is the STRUCTURE DECOMPOSITION figure of embodiment shown in Figure 7.
Number in the figure is:
1 substrate; 2 conductive electrodes; The 2-1 anode electrode; The 2-2 cathode electrode; The 2-3 short-circuiting electrode; 3 dielectric isolation layers; 4 reaction windows; 5 enzyme reaction films; The sample groove is led in 6 siphons; 7 thief hatchs; 7-1 thief hatch cave; 8 bonding dividing plates; 9 gas ports; 10 surface encapsulation plates.
Embodiment
Fig. 1 and Fig. 2 are the structural representation of first kind of embodiment of the utility model glucose in urine test-strips, in this embodiment, the glucose in urine test-strips comprises substrate 1, substrate 1 is provided with three strip conductive electrodes 2, be respectively anode electrode 2-1, cathode electrode 2-2 and short-circuiting electrode 2-3, wherein short-circuiting electrode 2-3 is between anode electrode 2-1 and cathode electrode 2-2, and join with cathode electrode 2-2, part is provided with dielectric isolation layer 3 on conductive electrode 2, one end of this dielectric isolation layer 3 is concordant with substrate 1, the other end is between the concordant end of the conducting part of strip conductive electrode 2 and described dielectric isolation layer 3, so that the electrode conducting part of conductive electrode 2 front ends is exposed outside; Offer reaction window 4 on described dielectric isolation layer 3, this reaction window 4 is the square groove that be arranged in parallel with dielectric isolation layer 3, and its span is while covered cathode electrode 2-2 and anode electrode 2-1, is pasted with enzyme reaction film 5 in reaction window 4; On described dielectric isolation layer 3, be provided with a bonding dividing plate 8, on this dividing plate with dielectric isolation layer 3 on offer bar shaped with the corresponding position of reaction window 4 siphon lead sample groove 6, the end that sample groove 6 close electrode conducting parts are led in this siphon offers a gas port 9, when entering reaction window 4, discharge the usefulness of gas to make urine sample, this gas port 9 is a bar-shaped trough, runs through the narrow end of bonding dividing plate 8; This siphon is led sample groove 6 and is offered the thief hatch 7 of a circle away from an end of electrode conducting part, and sample groove 6 is led in described thief hatch 7, siphon and gas port 9 threes are interconnected; On described bonding dividing plate 8, also be pasted with a surface encapsulation plate 10, on this surface encapsulation plate 10 with the corresponding position of thief hatch 7 offer one with the corresponding circular thief hatch cave 7-1 of thief hatch 7 sizes.
Fig. 3 is the structural representation of this second kind of novel embodiment, the difference of it and first embodiment is: the siphon on bonding dividing plate 8 is led sample groove 6 and is extended until the termination of bonding dividing plate 8 towards the direction away from substrate 1 top electrode conducting part, thereby forms the thief hatch 7 on this bonding dividing plate 8 in this end; Be pasted on this moment on the surface encapsulation plate 10 on the bonding dividing plate 8 and do not offer any thief hatch cave 7-1.
Fig. 4 is the structural representation of this third novel embodiment, the difference of it and first embodiment is: only offer siphon and lead sample groove 6 and thief hatch 7 on bonding dividing plate 8, this siphon is led sample groove 6 and is extended until the termination of bonding dividing plate 8 towards the direction away from substrate 1 top electrode conducting part, thereby forms the thief hatch 7 on this bonding dividing plate 8 in this end; Be pasted on the surface encapsulation plate 10 on the bonding dividing plate 8 corresponding position of leading sample groove 6 this moment and offer the gas port 9 of a circle with siphon.
Fig. 5 and Fig. 6 are the structural representation of this novel the 4th kind of embodiment, and the difference of it and first embodiment is: described thief hatch cave 7-1 be opened on the substrate with bonding dividing plate 8 on the corresponding position of circular thief hatch 7.
Fig. 7 and Fig. 8 are the structural representation of this 5th kind of novel embodiment, and this embodiment is close with this third novel embodiment, and except not having surface encapsulation plate 10, other structure is all identical with the 3rd embodiment.

Claims (10)

1. glucose in urine test-strips, comprise substrate (1), it is characterized in that: substrate (1) is provided with three strip conductive electrodes (2), be respectively anode electrode (2-1), cathode electrode (2-2) and short-circuiting electrode (2-3), short-circuiting electrode wherein (2-3) joins with anode electrode (2-1) or cathode electrode (2-2), part is provided with dielectric isolation layer (3) so that the electrode conducting part of conductive electrode (2) front end is exposed outside on conductive electrode (2), offer reaction window (4) on the described dielectric isolation layer (3), the span of this reaction window (4) is while covered cathode electrode (2-2) and anode electrode (2-1), is pasted with enzyme reaction film (5) in reaction window (4); On described dielectric isolation layer (3), be provided with a bonding dividing plate (8), offer thief hatch (7) and siphon on this dividing plate (8) and lead sample groove (6), both are interconnected, wherein thief hatch (7) is arranged at the end away from substrate (1) top electrode conducting part, and offer position and the dielectric isolation layer (3) of sample groove (6) led in siphon, and to go up the position of reaction window (4) corresponding.
2. glucose in urine test-strips according to claim 1 is characterized in that: also offer on the described bonding dividing plate (8) with siphon and lead the gas port (9) that sample groove (6) communicates, this gas port (9) runs through the narrow end of bonding dividing plate (8).
3. glucose in urine test-strips according to claim 1 is characterized in that: also be provided with a surface encapsulation plate (10) on described bonding dividing plate (8), the corresponding position of leading sample groove (6) with siphon on it offers gas port (9).
4. glucose in urine test-strips according to claim 2 is characterized in that: also be provided with a surface encapsulation plate (10) on described bonding dividing plate (8).
5. according to claim 3 or 4 described glucose in urine test-strips, it is characterized in that: described reaction window (4) is the square groove that be arranged in parallel with dielectric isolation layer (3).
6. glucose in urine test-strips according to claim 5 is characterized in that: described siphon is led sample groove (6) towards extending until the termination of bonding dividing plate (8) away from the direction of substrate (1) top electrode conducting part, thereby forms the thief hatch (7) on this bonding dividing plate (8).
7. glucose in urine test-strips according to claim 5 is characterized in that: described thief hatch (7) is opened in the end that sample groove (6) are led in siphon, and gas port (9) is opened in the front end that sample groove (6) are led in siphon.
8. glucose in urine test-strips according to claim 7 is characterized in that: described surface encapsulation plate (10) is gone up and thief hatch (7) corresponding position, position offers and thief hatch (7) shape corresponding thief hatch cave (7-1).
9. glucose in urine test-strips according to claim 7 is characterized in that: described substrate (1) is gone up and thief hatch (7) corresponding position, position offers and thief hatch (7) shape corresponding thief hatch cave (7-1).
10. glucose in urine test-strips according to claim 7 is characterized in that: described thief hatch (7) is for circular or semicircle.
CN2010202235846U 2010-06-10 2010-06-10 Urine sugar test strip Expired - Lifetime CN201697890U (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102565153A (en) * 2011-12-27 2012-07-11 桂林乐尔医疗器械有限公司 Electrode type urine glucose testing strip with function of pretreating detected sample
CN103105426A (en) * 2013-01-16 2013-05-15 桂林中辉科技发展有限公司 Urine glucose testing method and biosensor used in method
CN103412026A (en) * 2013-08-30 2013-11-27 江苏鱼跃医疗设备股份有限公司 Biosensor and manufacturing method thereof
CN104330448A (en) * 2014-10-31 2015-02-04 桂林中辉科技发展有限公司 High-sensitivity electrode type uric acid test paper and manufacturing method thereof
CN105122017A (en) * 2013-03-15 2015-12-02 聚合物技术系统公司 Hybrid strip

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102565153A (en) * 2011-12-27 2012-07-11 桂林乐尔医疗器械有限公司 Electrode type urine glucose testing strip with function of pretreating detected sample
CN102565153B (en) * 2011-12-27 2013-11-13 桂林乐尔医疗器械有限公司 Electrode type urine glucose testing strip with function of pretreating detected sample
CN103105426A (en) * 2013-01-16 2013-05-15 桂林中辉科技发展有限公司 Urine glucose testing method and biosensor used in method
CN105122017A (en) * 2013-03-15 2015-12-02 聚合物技术系统公司 Hybrid strip
CN103412026A (en) * 2013-08-30 2013-11-27 江苏鱼跃医疗设备股份有限公司 Biosensor and manufacturing method thereof
CN104330448A (en) * 2014-10-31 2015-02-04 桂林中辉科技发展有限公司 High-sensitivity electrode type uric acid test paper and manufacturing method thereof

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