CN201586220U - Punch of Chinese medicinal pill forming component - Google Patents

Punch of Chinese medicinal pill forming component Download PDF

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Publication number
CN201586220U
CN201586220U CN2010200033801U CN201020003380U CN201586220U CN 201586220 U CN201586220 U CN 201586220U CN 2010200033801 U CN2010200033801 U CN 2010200033801U CN 201020003380 U CN201020003380 U CN 201020003380U CN 201586220 U CN201586220 U CN 201586220U
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China
Prior art keywords
crown shape
spherical crown
drift
punch
groove
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Expired - Lifetime
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CN2010200033801U
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Chinese (zh)
Inventor
柯树泉
柯少彬
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Guangdong Taiantang Pharmaceutical Co Ltd
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Abstract

A punch of a Chinese medicinal pill forming component comprises an upper punch and a lower punch. The upper punch and the lower punch are both provided with a spherical cap-shaped groove. The punch is characterized in that the depth of the spherical cap-shaped groove of the upper punch is smaller than the spherical radius of the spherical cap-shaped groove, and the depth of the spherical cap-shaped groove of the lower punch is smaller than the spherical radius of the spherical cap-shaped groove. Compared with the prior art, the punch provided by the utility model increases air spillover area, and solves the problem during pill forming that pills are loosened or stuck on the punch.

Description

A kind of drift of medicine pill shaped component
Technical field
This utility model relates to a kind of medicine pill shaped component, more specifically to a kind of drift of medicine pill shaped component.
Background technology
Mention Chinese medicine, people can expect traditional medicine of stewing soup very naturally.Because the inconvenience that traditional medicine of stewing soup brings to the patient, make with Chinese crude drug fine powder or Chinese crude drug extract to be raw material, the medicine pill that adds suitable binding agent or other adjuvants and make just arises at the historic moment, and warmly pursued by numerous Chinese medicine manufacturer, produce many pills such as honeyed pill, water-honeyed pill, the watered pill, paste pill, concentrated pill by general system or the system of moulding.
But just at present existing state-of-the-art technology is a pressing, and its adopts wet method system granule, drying, and the tablet machine that low punch is hemispherical groove on the reuse carries out the way of deep-draw pelleting and makes.Owing to " go up low punch and be hemispherical groove "; in the pelleting process, be easy to produce because of the air in granule or the fine powder and can not in time overflow; and produce ball, loose ball, sticking or the bad problem of other molding of loosing, can not be widely used in the production of medicine pill.
The utility model content
The purpose of this utility model is that prior art is improved, and a kind of drift of medicine pill shaped component is provided, and pill air in pressing process can better be overflowed, and the technical scheme of employing is as follows:
The drift of a kind of medicine pill shaped component of the present utility model, comprise upper punch, low punch, upper punch, low punch all have spherical crown shape groove, it is characterized in that: the spherical crown shape depth of groove of described upper punch is less than the spherical radius of this spherical crown shape groove, and the spherical crown shape depth of groove of low punch is less than the spherical radius of this spherical crown shape groove.When punching course is finished, still exist spacing between the last low punch like this.
Be equipped with the outgas aperture that communicates with spherical crown shape groove on above-mentioned upper punch, the low punch, the number range of outgas aperture is 1-7, and the number of outgas aperture is an odd number.
Above-mentioned outgas aperture is that remote stomidium between the 0.6-1 millimeter is formed by diameter less than 0.5 millimeter proximal orifice and diameter range, and proximal orifice and remote stomidium tool concentric shafts also communicate.
Above-mentioned outgas aperture is generally implemented on greater than 5 millimeters drifts at spherical crown shape slot opening diameter, best for spherical crown shape slot opening diameter range be the 6-18 millimeter.
A kind of preferable scheme, the spherical crown shape depth of groove scope of above-mentioned upper and lower drift is 1/4~1/3 of this spherical crown shape slot opening diameter.The spherical crown shape depth of groove scope that is to say upper punch be upper punch spherical crown shape slot opening diameter 1/4~1/3, the spherical crown shape depth of groove scope of low punch be low punch spherical crown shape slot opening diameter 1/4~1/3.
The slot opening diameter of preferred upper and lower drift is 85~95% of its final molding pill maximum gauge.In the punch forming process, the minimum spacing scope between the spherical crown shape slot opening place face of upper and lower drift is 1/4~1/2 (the spherical crown shape groove shapes of upper and lower drift is all identical with size) of spherical crown shape slot opening diameter.
This utility model beneficial effect against existing technologies is, because the spherical crown shape depth of groove of upper and lower drift is all less than its spherical radius, go up between the low punch in the punching course and have spacing all the time, enlarge air and overflowed area, and for the molding of more powder body (its diameter is greater than 5 millimeters), on drift, beat odd number outgas aperture again, increased the spherical pellet base easily with regard to extruding like this, be not prone to the phenomenon of loose ball, diffusing ball or sticking again.
Description of drawings
Fig. 1 is the front elevational view of this utility model embodiment 1;
Fig. 2 is the user mode sketch map of this utility model embodiment 1.
The specific embodiment
Embodiment 1
As shown in Figure 1, the drift of the medicine pill shaped component of present embodiment, comprise upper punch 1, low punch 2, upper punch 1 has the first spherical crown shape groove 11, low punch 2 has the second spherical crown shape groove 21, and the described first spherical crown shape groove 11, the second spherical crown shape groove, 21 degree of depth are all less than its spherical radius.
Upper punch 1 is provided with the first outgas aperture 4 that communicates with the first spherical crown shape groove 11, and low punch is provided with the second outgas aperture 5 that communicates with the second spherical crown shape groove 21.
The first above-mentioned outgas aperture 4 is made up of less than first remote stomidium 42 that 0.5 millimeter first proximal orifice 41 and diameter are 1 millimeter diameter, and first proximal orifice 41 and first remote stomidium, 42 tool concentric shafts also communicate.
The second above-mentioned outgas aperture 5 is made up of less than second remote stomidium 52 that 0.5 millimeter second proximal orifice 51 and diameter are 1 millimeter diameter, and second proximal orifice 51 and second remote stomidium, 52 tool concentric shafts also communicate.
Introduce the pressing () of Hu Shi LIUSHEN WAN (watered pill) below
Prescription is from " Chinese traditional patent formulation preparation " the 9th the 117th page of (Z9-117) standard numbering: WS3-B-1775-94.Calculus Bovis 5g, Borneolum Syntheticum 5g, Cinnabaris 10g, Herba Menthae 5g, Moschus 7g, Fel Ursi 5g, Radix Isatidis 5g, Realgar 20g, Radix Glycyrrhizae 5g, Flos Lonicerae 5g, Venenum Bufonis 8g.
More than ten simply, it is an amount of that Venenum Bufonis adds warm water, put temperature place dipping 24 hours, the furnishing pasty state is standby; Cinnabaris, Realgar water fly or are ground into impalpable powder; Radix Glycyrrhizae, Flos Lonicerae, Radix Isatidis, Herba Menthae are ground into fine powder, sieving for standby; With Calculus Bovis, Borneolum Syntheticum, Moschus, Fel Ursi porphyrize, with above-mentioned powder mixing, get mixture, again Venenum Bufonis water to be stuck with paste in the adding mixture, dry-pressing is granulated.
As shown in Figure 2, selecting spherical crown shape slot opening diameter D for use is 1 millimeter upper and lower drift ball, and the minimum spacing B between the first spherical crown shape groove 11, the second spherical crown shape groove, the 21 opening place faces is that the degree of depth C of 0.5 millimeter, the first spherical crown shape groove 11 and the second spherical crown shape groove 21 is 0.33 millimeter.Rotating speed is made ball at 5 rev/mins tablet machine (adopting rotary tablet machine in the present embodiment) to above-mentioned material 3 deep draws.Loose ball does not appear in pressing process, the phenomenons such as ball and sticking of loosing.If the filler of pellet press is increased or reduces, adjust corresponding pressure, pelleting drift gap is greater than 0.5 millimeter, and then ball shape is ugly, and after whole ball increased circle, weight differential obviously rose.If adjust minimum spacing to the 0.49-0.1 millimeter, phenomenons such as sticking, loose ball even impaction then occur.
With the burnt MEDULLA JUNCI coating, promptly get final finished at last.
The applicant takes into full account the air overflow problem in the medicated powder, and through test of many times, summary draws: enlarging air overflows area (the spherical crown shape depth of groove of upper punch 1, low punch 2 is all less than its spherical radius) on the one hand; The rotating speed (range of revolution of rotary tablet machine is at 5~45 rev/mins) that slows down on the other hand prolongs pelleting time of drift, can extrude to increase the spherical pellet base easily, is not prone to loose ball again, the phenomenon of loose ball or sticking.In addition, owing on upper punch 1, low punch 2, be equipped with the outgas aperture that communicates with spherical crown shape groove, when upper punch 1 downward (low punch 2 makes progress simultaneously) when advancing gas earlier flow to first remote stomidium 42 (second proximal orifice 51 flows to second remote stomidium 52) from first proximal orifice 41, hole depth by first proximal orifice 41 (second proximal orifice 51) is extremely shallow, and powder is difficult for resting on first proximal orifice 41 (second proximal orifice 51); When upper punch 1 upwards (low punch 2 is downward) when advancing first proximal orifice, 41 belows (second proximal orifice, 51 tops) volume increase and form negative pressure, residual powder flows away to spherical crown shape groove direction.This design makes the outgas hole be difficult for stopping up and playing the effect of good release gas.
Embodiment 2
The pressing (two) of Hu Shi LIUSHEN WAN (watered pill)
Prescription is from " Chinese traditional patent formulation preparation " the 9th the 117th page of (Z9-117) standard numbering: WS3-B-1775-94.Calculus Bovis 5g, Borneolum Syntheticum 5g, Cinnabaris 10g, Herba Menthae 5g, Moschus 7g, Fel Ursi 5g, Radix Isatidis 5g, Realgar 20g, Radix Glycyrrhizae 5g, Flos Lonicerae 5g, Venenum Bufonis 8g.
More than ten simply, Venenum Bufonis, Borneolum Syntheticum, Moschus, Herba Menthae add the alcohol reflux dissolving, sealing is preserved standby; Cinnabaris, Realgar water fly or are ground into impalpable powder; Radix Glycyrrhizae, Flos Lonicerae, Radix Isatidis add 8-10 times of water gaging and extract secondary, and concentrate drying becomes dried cream powder, granulate with all the other fine powder dry-pressing; Alcoholic solution such as Bufo siccus are sprayed into granule, can add an amount of disintegrating agent, lubricant.
The difference of present embodiment and embodiment 1 is: the minimum spacing B between the first spherical crown shape groove 11, the second spherical crown shape groove, the 21 opening place faces is that 0.33 millimeter, the degree of depth C of the first spherical crown shape groove 11, the second spherical crown shape groove 21 are 0.25 millimeter.
Rotating speed is made ball at 25 rev/mins rotary tablet machine to above-mentioned material 3 deep draws.Loose ball does not appear in pressing process, the phenomenons such as ball and sticking of loosing.As rotating speed being opened when changeing greater than 25, the ball phenomenon of loosing loose ball then appears.
With the burnt MEDULLA JUNCI coating, promptly get final finished at last.
Embodiment 3
Herba Sidae Rhombifoliae soup ball (concentrated pill)
According to the 13 the 21st page of standard: WS3-B-2470-97 of standard standard for traditional Chinese medicines, get Radix Bupleuri 60g, Radix Codonopsis 30g, Fructus Jujubae 30g, Radix Scutellariae 30g, Rhizoma Pinelliae 30g, Radix Glycyrrhizae 20g, Rhizoma Zingiberis Recens 16g.
More than seven flavors, Radix Bupleuri, Rhizoma Zingiberis Recens extract volatile oil with steam distillation, the aqueous solution after the distillation in addition device is preserved; Medicinal residues and Radix Scutellariae, Radix Codonopsis, Fructus Jujubae decoct with water secondary, and each 2 hours, collecting decoction filtered, and filtrate and above-mentioned aqueous solution merge, concentrating under reduced pressure, drying; The Rhizoma Pinelliae, Radix Glycyrrhizae powder are broken into fine powder, sieve mixing; With above dried cream powder, fine powder and volatile oil mixing, dry-pressing is granulated, dry (or the mixing after drying, dry-pressing system granule).
The difference of present embodiment and embodiment 1 is: with more than 95% of above-mentioned material, selecting spherical crown shape slot opening diameter D for use is that minimum spacing B between 3.5 millimeters, upper and lower drift slot opening place face is that 1.4 millimeters, depth of groove C are 1 millimeter, and rotating speed is made ball at 45 rev/mins rotary tablet machine to above-mentioned material deep draw.Loose ball does not appear in pressing process, the phenomenons such as ball and sticking of loosing.
With the remaining material below 5% the above-mentioned pill that is pressed into is increased circle at last, polishing promptly gets pill finished product finally.
Embodiment 4
QIJU DIHUANG WAN (concentrated pill)
According to the 8th the 77th page of standard: WS3-B-1543-93 of the Chinese medicine standard side of one-tenth medicine, get Fructus Lycii 40g, Flos Chrysanthemi 40g, Radix Rehmanniae Preparata 160g, Rhizoma Dioscoreae 80g, Cortex Moutan 60g, Fructus Corni (system), 80g, Poria 60g.
Preparation method, more than eight flavors, Rhizoma Alismatis, Poria powder are broken into fine powder, decoct with water secondary, 3 hours for the first time, 2 hours for the second time, collecting decoction filtered, filtrate is condensed into the extractum that relative density is 1.30~1.35 (20 ℃); The Radix Rehmanniae Preparata section decocts with water three times, and 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, collecting decoction filtered, and filtrate is condensed into extractum or the dried cream powder that relative density is 1.30~1.35 (20 ℃); Get Fructus Lycii and make solvent with 45% ethanol, Fructus Corni 53.3g, Cortex Moutan 33.5g and Flos Chrysanthemi are made solvent with 70% ethanol, according to the percolation under liquid extractum and the extractum item (17 pages of appendix), flood after 24 hours, carry out percolation respectively, the collection liquid of filtering merges two kinds of liquid of filtering, and reclaims ethanol and is condensed into extractum or the dry powder that relative density is 1.30~1.35 (20 ℃); Rhizoma Dioscoreae, remaining Cortex Moutan and powder of Fructus Corni are broken into fine powder,, roll granulation with dry powder with above-mentioned each clear paste mixing.
The difference of present embodiment and embodiment 1 is: spherical crown shape slot opening diameter D is 6.0 millimeters, and the degree of depth C of the first spherical crown shape groove 11 and the second spherical crown shape groove 21 is 1.25 millimeters, regulates the tablet machine rotating speed about 35 rev/mins, carries out pelleting.Pressing process is comparatively smooth, loose ball, diffusing ball and sticking phenomenon do not occur.If will improve rotating speed, can on upper and lower drift, beat 1-3 outgas aperture.For son makes the outgas aperture not blocked, adopt the way of 2 punchings, to use earlier less than 0.5 millimeter or 0.2 millimeter drill bit punching, little reuse acupuncture is logical to get final product, and 1 millimeter drill bit punching of reuse is estimated to make the little hole depth in front be retained in 1 millimeter.Be pressed into concentrated pill, polishing, promptly.This moment, the tablet machine rotating speed can be increased to 45-50 rev/min.
Have the piller better effects if of the drift of outgas aperture for 16 millimeters of compactings.

Claims (9)

1. the drift of a medicine pill shaped component, comprise upper punch, low punch, upper punch, low punch all have spherical crown shape groove, it is characterized in that: the spherical crown shape depth of groove of described upper punch is less than the spherical radius of this spherical crown shape groove, and the spherical crown shape depth of groove of low punch is less than the spherical radius of this spherical crown shape groove.
2. the drift of medicine pill shaped component as claimed in claim 1 is characterized in that: be equipped with the outgas aperture that communicates with spherical crown shape groove on above-mentioned upper punch, the low punch, the number range of outgas aperture is 1-7, and the number of outgas aperture is an odd number.
3. the drift of medicine pill shaped component as claimed in claim 2 is characterized in that: above-mentioned outgas aperture is made up of less than the remote stomidium that 0.5 millimeter proximal orifice and diameter range are the 0.6-1 millimeter diameter, and proximal orifice and remote stomidium tool concentric shafts also communicate.
4. as the drift of claim 2 or 3 described medicine pill shaped components, it is characterized in that: above-mentioned spherical crown shape slot opening diameter is greater than 5 millimeters.
5. the drift of medicine pill shaped component as claimed in claim 4 is characterized in that: above-mentioned spherical crown shape slot opening diameter range is the 6-18 millimeter.
6. as the drift of any described medicine pill shaped component among the claim 1-3, it is characterized in that: the spherical crown shape depth of groove scope of above-mentioned upper and lower drift is 1/4~1/3 of this spherical crown shape slot opening diameter.
7. the drift of medicine pill shaped component as claimed in claim 4 is characterized in that: the spherical crown shape depth of groove scope of above-mentioned upper and lower drift is 1/4~1/3 of this spherical crown shape slot opening diameter.
8. as the drift of any described medicine pill shaped component among the claim 1-3, it is characterized in that: the spherical crown shape groove shapes of above-mentioned upper and lower drift is all identical with size, and the minimum spacing scope between the spherical crown shape slot opening place face of upper and lower drift is 1/4~1/2 of a spherical crown shape slot opening diameter.
9. the drift of medicine pill shaped component as claimed in claim 4, it is characterized in that: the spherical crown shape groove shapes of above-mentioned upper and lower drift is all identical with size, and the minimum spacing scope between the spherical crown shape slot opening place face of upper and lower drift is 1/4~1/2 of a spherical crown shape slot opening diameter.
CN2010200033801U 2010-01-06 2010-01-06 Punch of Chinese medicinal pill forming component Expired - Lifetime CN201586220U (en)

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CN2010200033801U CN201586220U (en) 2010-01-06 2010-01-06 Punch of Chinese medicinal pill forming component

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Application Number Priority Date Filing Date Title
CN2010200033801U CN201586220U (en) 2010-01-06 2010-01-06 Punch of Chinese medicinal pill forming component

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104983572A (en) * 2015-06-30 2015-10-21 刘宇 Pill granulation device
CN104983573A (en) * 2015-06-30 2015-10-21 刘宇 Granulation device for pharmacy
CN114053148A (en) * 2021-11-19 2022-02-18 李任田 Adjustable pill making machine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104983572A (en) * 2015-06-30 2015-10-21 刘宇 Pill granulation device
CN104983573A (en) * 2015-06-30 2015-10-21 刘宇 Granulation device for pharmacy
CN114053148A (en) * 2021-11-19 2022-02-18 李任田 Adjustable pill making machine

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C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: GUANGDONG TAI'ANTANG PHARMACEUTICAL CO., LTD.

Free format text: FORMER OWNER: GUANGDONG TAIANTANG PHARMACEUTICAL CO., LTD.

Effective date: 20120504

C41 Transfer of patent application or patent right or utility model
COR Change of bibliographic data

Free format text: CORRECT: ADDRESS; FROM: 515021 SHANTOU, GUANGDONG PROVINCE TO: 515041 SHANTOU, GUANGDONG PROVINCE

TR01 Transfer of patent right

Effective date of registration: 20120504

Address after: 515041 Guangdong city of Shantou province 11R2-2 Jinyuan Industrial Zone area first, second

Patentee after: Guangdong Taiantang Pharmaceutical Co., Ltd.

Address before: 515021 Guangdong city of Shantou province 11R2-2 Jinyuan Industrial Zone area first floor, two floor preparation on the eastern side

Patentee before: Guangdong Taiantang Pharmaceutical Co., Ltd.

CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20100922