CN201454549U - long-acting biochemical reagent bottle - Google Patents
long-acting biochemical reagent bottle Download PDFInfo
- Publication number
- CN201454549U CN201454549U CN2009200861170U CN200920086117U CN201454549U CN 201454549 U CN201454549 U CN 201454549U CN 2009200861170 U CN2009200861170 U CN 2009200861170U CN 200920086117 U CN200920086117 U CN 200920086117U CN 201454549 U CN201454549 U CN 201454549U
- Authority
- CN
- China
- Prior art keywords
- bottle
- reagent
- cylindrical body
- long
- bottleneck
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
A long-acting biochemical reagent bottle comprises a bottle body, bottle mouths and a bottle cap, and is characterized in that two bottle mouths are arranged on the bottle body, and a cylindrical body is formed by vertically extending into the bottle body from one of the bottle mouths; the inner diameter of the cylindrical body is 5 to 7 mm, and the lower edge of the cylindrical body is 3 to 6 mm away from the bottle bottom; and small holes are formed on the wall of the cylindrical body. The utility model achieves the purpose of delaying the disintegration of reagent through the method of preventing the reagent from being in contact with flowable air, so that the effect of delaying the disintegration of various biochemical reagents in the open bottle is remarkable, the stability of the reagent in the open bottle can be efficiently improved, the validity period of the reagent is prolonged, and the daytime variation CV of testing results is remarkably lowered. Therefore, the reagent bottle has significance to both the cost control and the quality control of a laboratory.
Description
(1) technical field: the utility model relates to the biochemical test equipment, is a kind of long-acting biochemical reagents bottle.
(2) prior art: the decaying phenomenon after the biochemical reagents uncork is the FAQs in the clinical chemistry test work, the decay of reagent can cause testing result the tendency variation to occur, when the decay degree surpasses the scope of reagent factory settings, then be judged as inefficacy, so the decay of reagent bottle after uncapping becomes and influence the key factor that reagent effect phase and testing result make a variation in the daytime.
Biochemical investigation reagent effect phase under Kaifeng state not is generally 1 to 2 year, and the effect phase that is written into Biochemical Analyzer after the uncork then often has only 15 days to 3 months, even shorter.The air of long-term contact flow volatilizees after main cause and the reagent uncork, oxidation (or reduction), deliquescence, crystallization or germ contamination etc. are relevant, and reagent active ingredient is degraded gradually.This natural decay process is capable of blocking usually and can only delay by means of different.
(3) summary of the invention: the utility model is exactly to provide a kind of long-acting biochemical reagents bottle that can effectively delay biochemical reagents decay after the uncork at the problems referred to above.
Concrete scheme of the present utility model is: long-acting biochemical reagents bottle, have bottle, bottleneck and bottle cap, it is characterized in that: design has two bottlenecks on bottle, and vertically in bottle, extend into cylindrical body from one of them bottleneck, described cylindrical body internal diameter 5-7mm, its lower edge 3-6mm at the bottom of the bottle, and on the tubular body wall, have aperture.
Aperture on the described tubular body wall is apart from bottleneck 15~20mm, and diameter is 0.5~1mm.
The utlity model has following advantage:
1. remarkable to the decay effect after delaying various biochemical reagents and uncapping, can effectively improve stability after the reagent uncork, prolong reagent and imitate the phase, significant for the laboratory cost control.
2. can effectively reduce the CV of variation in the daytime of testing result, the laboratory inspection quality is significant for improving.
3. can effectively prolong the calibration cycle of all kinds of biochemical projects, help reducing the cost of reagent, caliberator and Quality Control thing.
4. the utility model production cost is close with common biochemical reagent bottle, but has superior performance, and alternative traditional common biochemical reagent bottle is widely used in automatic clinical chemistry analyzer and detects.
The performance parameter of the utility model and common biochemical reagent bottle is (seeing the following form) relatively
The performance of long-acting biochemical reagents bottle and common biochemical reagent bottle relatively
Below be the utility model and common biochemical reagent bottle store reagents test experience:
Use general reagent bottle and long-acting biochemical reagents bottle to store with batch biochemical reagents on automatic clinical chemistry analyzer respectively, detect simultaneously normal value and pathology value pooled serum every day, and the tendency of observing testing result changes;
Laboratory apparatus: the Japanese TBA120FR of Toshiba automatic clinical chemistry analyzer;
Calibration object: Luo Shi Bao Lingman human serum matrix composite calibration object;
Quality-control product: healthy people's fresh mix serum preparation normal value quality controlled serum; Inpatient's fresh mix serum preparation pathology value quality controlled serum.℃ freezing preservation of sealing packing postposition-20.
(4) description of drawings:
Fig. 1 is the utility model structural representation;
Fig. 2 is the utility model working state schematic representation;
Fig. 3 is a tolal bile acid determination intermediate value sample graphs;
Fig. 4 is the high value sample graphs of tolal bile acid determination;
Fig. 5 is the LP determination sample graphs;
Fig. 6 is a creatinine assay intermediate value sample graphs;
Fig. 7 is the high value sample graphs of creatinine assay;
Fig. 8 is that sodium ion is measured the intermediate value sample graphs;
Fig. 9 is that sodium ion is measured high value sample graphs;
Figure 10 alkaline phosphatase assay intermediate value sample graphs;
Figure 11 is the high value sample graphs of alkaline phosphatase assay.
Among the figure: 1-bottle, 2-bottleneck, 3-bottle cap, 4-bottleneck, 5-bottle cap, 6-cylindrical body, 7-reagent needles, 8-reagent, 9-dead space, 10-aperture.
(5) specific embodiment:
Referring to Fig. 1, making material of the present utility model is a common plastics, have bottle 1, bottleneck 2 and bottle cap 3, bottle thickness 1mm, particularly: also designing on the bottle 1 has bottleneck 4 and bottle cap 5, and vertically extends into cylindrical body 6 from bottleneck 4 in bottle 1, described cylindrical body 6 internal diameter 5mm, its lower edge also is 5mm at the bottom of bottle, and has the aperture 10 that a diameter is 1mm apart from bottleneck 20mm place on the tubular body wall, promptly constitutes the utility model.
Principle of the present utility model (referring to Fig. 1, Fig. 2): after the general reagent bottle is uncapped, but area that the reagent liquid level contacts with moving air and whole bottle floor space sizableness, and after the utility model uncaps, but reagent 8 liquid levels and moving air contact portion, its area size equates with reagent bottleneck 4 areas, is significantly smaller than the general reagent bottle.Though the contact area of air in the utility model reagent 8 liquid levels and bottle 1 dead space 9, approximate a bottle floor space, but because air does not have flowability (though have aperture 10 on the tubular body wall in the dead space 9, but because its diameter is minimum, can not cause flowing of dead space 9 interior air), therefore can not cause the quick decay of reagent 8.And on the tubular body wall, open the purpose of aperture 10, be to allow the bottle outer air slowly enter in the dead space 9, to keep dead space 9 inner air pressures and external air pressure balance, make cylindrical body 6 interior liquid levels and dead space 9 interior liquid levels reach double altitudes, thereby make amount of reagent in the automatic biochemistry analyzer reagent needles energy correct detection bottle.Performance master's evaluation test of being undertaken by a large amount of biochemical investigation projects confirms, this structure for improve stability after the reagent uncork, prolong reagent imitate the phase, reduce assay make a variation in the daytime (CV) have remarkable effect.
The utility model use (referring to Fig. 2):
1. reagent can:
2. the machine of going up is prepared: seal bottlenecks 2 with bottle cap 3 before going up machine.
3. duty: reagent needles 7 stretches into from bottleneck 4 and surveys and draw reagent 8 in the cylindrical body 6.
The utility model and common biochemical reagent bottle store reagents test experience:
On automatic clinical chemistry analyzer, use general reagent bottle and long-acting biochemical reagents bottle to store respectively with batch biochemical reagents, detect simultaneously normal value and pathology value pooled serum every day, the tendency of observing testing result changes laboratory apparatus: the Japanese TBA120FR of Toshiba automatic clinical chemistry analyzer; Calibration object: Luo Shi Bao Lingman human serum matrix composite calibration object; Quality-control product: healthy people's fresh mix serum preparation normal value quality controlled serum; Inpatient's fresh mix serum preparation pathology value quality controlled serum.℃ freezing preservation of sealing packing postposition-20.Correlation curve figure referring to Fig. 3-Figure 11 (
Be long-acting biochemical reagents bottle testing result;
Be common biochemical reagents testing result).
Claims (2)
1. long-acting biochemical reagents bottle has bottle, bottleneck and bottle cap, it is characterized in that: design has two bottlenecks on bottle, and vertically in bottle, extend into cylindrical body from one of them bottleneck, described cylindrical body internal diameter 5-7mm, its lower edge 3-6mm at the bottom of the bottle, and on the tubular body wall, have aperture.
2. long-acting biochemical reagents bottle according to claim 1 is characterized in that: the aperture on the described tubular body wall is apart from bottleneck 15~20mm, and diameter is 0.5~1mm.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009200861170U CN201454549U (en) | 2009-05-27 | 2009-05-27 | long-acting biochemical reagent bottle |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009200861170U CN201454549U (en) | 2009-05-27 | 2009-05-27 | long-acting biochemical reagent bottle |
Publications (1)
Publication Number | Publication Date |
---|---|
CN201454549U true CN201454549U (en) | 2010-05-12 |
Family
ID=42381896
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009200861170U Expired - Fee Related CN201454549U (en) | 2009-05-27 | 2009-05-27 | long-acting biochemical reagent bottle |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN201454549U (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103041875A (en) * | 2011-10-15 | 2013-04-17 | 四川制药制剂有限公司 | Sputtering-prevention multi-mouth reagent bottle |
CN104769439A (en) * | 2012-10-30 | 2015-07-08 | 株式会社日立高新技术 | Reagent container and automated analyzer |
GB2542757A (en) * | 2015-08-13 | 2017-04-05 | Acquascience Ltd | A Method for Supplying Histology Reagents |
WO2021237653A1 (en) * | 2020-05-29 | 2021-12-02 | Leica Biosystems Nussloch Gmbh | Reagent container and tissue processor |
-
2009
- 2009-05-27 CN CN2009200861170U patent/CN201454549U/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103041875A (en) * | 2011-10-15 | 2013-04-17 | 四川制药制剂有限公司 | Sputtering-prevention multi-mouth reagent bottle |
CN104769439A (en) * | 2012-10-30 | 2015-07-08 | 株式会社日立高新技术 | Reagent container and automated analyzer |
GB2542757A (en) * | 2015-08-13 | 2017-04-05 | Acquascience Ltd | A Method for Supplying Histology Reagents |
WO2021237653A1 (en) * | 2020-05-29 | 2021-12-02 | Leica Biosystems Nussloch Gmbh | Reagent container and tissue processor |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN201454549U (en) | long-acting biochemical reagent bottle | |
CN201697828U (en) | Digestion reaction device of on-line monitoring analyzer of water quality | |
CN111487210A (en) | Widely-applicable protein quantitative detection kit, detection method and application thereof | |
CA2791211C (en) | Metabolic rate indicator for cellular populations | |
CN100487426C (en) | Boron determination solution and colorimetric determination tube therefor | |
CN205786322U (en) | A kind of ATP fluoroscopic examination swab | |
CN212622249U (en) | Device for quickly detecting chloride ion content of sand for building | |
CN201757738U (en) | Portable water quality testing device | |
CN201368864Y (en) | Device used for rapidly detecting sulphate in water | |
CN203216895U (en) | Water quality detection device | |
CN201724876U (en) | Special sand content testing device | |
CN100498289C (en) | Cadmium determination solution and colorimetric determination tube therefor | |
CN206311491U (en) | A kind of disposable double reagent cuvette | |
CN201266164Y (en) | Device for counting urine cell tittle dyeing | |
CN103105425A (en) | Water quality detection device and method | |
CN215894375U (en) | Anion surfactant rapid survey case in drinking water | |
CN211391876U (en) | Split type concentrator tube | |
CN2840019Y (en) | Boron colorimetric estimation cylinder | |
CN107228943B (en) | The method for measuring bacterial content in fluid sample | |
CN204255863U (en) | A kind of integrated chemical reaction device for fast detecting | |
CN1766554B (en) | Mercury determination solution and colorimetric determination tube therefor | |
AU2021105058A4 (en) | Rapid visual colorimetric detection method for environmental pollutant sulfide ions based on peroxidase-like dnazyme | |
CN215768554U (en) | Water quality testing is with adding mark device | |
CN2840016Y (en) | Uranium colorimetric estimation cylinder | |
CN1773254B (en) | Selenium assaying liquid and colour comparision tube thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100512 Termination date: 20110527 |