CN201431691Y - Catheter with antimicrobial and hydrophilic coatings - Google Patents

Catheter with antimicrobial and hydrophilic coatings Download PDF

Info

Publication number
CN201431691Y
CN201431691Y CN2009203058013U CN200920305801U CN201431691Y CN 201431691 Y CN201431691 Y CN 201431691Y CN 2009203058013 U CN2009203058013 U CN 2009203058013U CN 200920305801 U CN200920305801 U CN 200920305801U CN 201431691 Y CN201431691 Y CN 201431691Y
Authority
CN
China
Prior art keywords
catheter
coating
hydrophilic
layer
antimicrobial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2009203058013U
Other languages
Chinese (zh)
Inventor
齐民
魏志勇
刘洪泽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dalian University of Technology
Original Assignee
Dalian University of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dalian University of Technology filed Critical Dalian University of Technology
Priority to CN2009203058013U priority Critical patent/CN201431691Y/en
Application granted granted Critical
Publication of CN201431691Y publication Critical patent/CN201431691Y/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Abstract

The utility model discloses a catheter with antimicrobial and hydrophilic coatings, and belongs to the technical field of medical appliances. The catheter has the following structure: the outer surface of the catheter is orderly coated with a layer of antimicrobial coating and a layer of hydrophilic coating, wherein the antimicrobial coating is a coating containing compositions such as chitin or chitosan and derivatives thereof; and the hydrophilic coating is a coating of polyethylene glycol, polyvinyl pyrrolidone or polyvinyl pyrrolidone-vinyl acetate hydrophilic polymer. The structural design that the antimicrobial coating and the hydrophilic coating are orderly coated on the outer surface of the catheter is simple and reasonable, and is favorable for dual effects of antibiosis and lubrication of the catheter; and the catheter is easy to produce on a large scale, has convenient use and operation, can effectively relieve the pain of patients and is convenient to be used by medical workers, is a generation-substituting product of a common catheter, and has good promotion and application values.

Description

A kind of antibiotic hydrophilic coating catheter
Technical field
This utility model belongs to technical field of medical instruments, relates to a kind of catheter, relates in particular to a kind of antibiotic and catheter hydrophilic coating of having.
Background technology
Medical catheter is one of medical device the most frequently used in the modern medical service practice.Traditional catheter is in its application process, for making conduit insert smooth and easy and avoiding damage to urethra, often need smear lubricant at front end, yet consumption and operation are difficult to hold, lubricant effect is unsatisfactory, and has increased foul link of a step in the feasible operation of the use of this added substance.There is certain sticking absorption on the surface of catheter to microorganisms such as antibacterials simultaneously, antibacterial in the easily subsidiary environment, make and very easily infect in the urethral catheterization process, needs of patients is taken antibiotic prophylaxis and the treatment that human body is had hazardness to a certain degree, and this infection makes therapeutic effect unsatisfactory because of the Drug resistance of antibacterial in the bacterial membrane, and very difficulty becomes.Because the existence of above-mentioned two big defectives needs frequently more to renew catheter, has not only caused sensual misery and financial burden to the patient, has also increased work load to medical personnel.
Summary of the invention
Technical problem to be solved in the utility model has provided a kind of antibiotic hydrophilic coating catheter with surperficial self-lubrication and infection function.
The technical scheme that this utility model adopted is:
This utility model is made up of catheter body, antibiotic layer and hydrophilic layer.Wherein antibiotic layer is coated in the outer surface of catheter body, at the outer surface coating hydrophilic layer of antibiotic layer.Dip-coating mode film forming is adopted in the coating coating.Described antimicrobial coating is the coating that comprises chitin and/or compositions such as chitosan and derivant thereof, and described hydrophilic coating is the coating of hydrophilic polymers such as Polyethylene Glycol, polyvinylpyrrolidone, polyvinylpyrrolidone vinyl acetate.
Effect of the present utility model and benefit are:
1, catheter adopts surperficial self-lubrication technology, hydrophilic polymer is coated in the catheter outer surface, dry back forms clear films, the rapid expansion forms hydrogel after meeting water, lubricant effect reaches highly lubricated effect considerably beyond conventional lubricant, significantly reduces the stimulation to mucous membrane of urethra, and urethral secretions and urine mineralization, reach safety, health, easy to operate.Hydrophilic polymers such as the Polyethylene Glycol that adopts, polyvinylpyrrolidone, polyvinylpyrrolidone vinyl acetate are the macromolecular compounds with good biocompatibility of studying for many years and having facts have proved, itself and all nontoxic at the intravital degradation product of people.
2, the antimicrobial coating of catheter adopts is that chitin or chitosan are as antimicrobial component.Chitin is extensively to be distributed in natural polysaccharide; it is the main component of animal shell; chitosan is the deacetylated product of chitin; chitin verified fully at antibacterial ability, and commute causes that antibacterials such as the escherichia coli, staphylococcus aureus, Candida albicans of urethra inflammation have good fungistatic effect.This anti-biotic material of chitin and chitosan is naturally occurring, and skin is had no stimulation, and is safe and reliable to human body, has no side effect etc.
3, antibiotic hydrophilic coating catheter structural design advantages of simple of the present utility model is convenient to produce and use, and is suitable for promotion and implementation.Earlier at ordinary urethral catheter surface applied ground floor antibiotic layer, then at antibiotic layer surface applied second layer hydrophilic layer, such coating structure design advantage is: when catheter is implanted, hydrophilic coating provides self-lubricating function, make that the catheter surface is super lubricated, catheter is implanted very easily; Catheter exposes antibiotic layer after hydrophilic polymer is water-soluble after implanting, the antibacterial action of performance chitin or chitosan, and have lasting antibacterial action.
Description of drawings
Accompanying drawing is this utility model structural representation.
The specific embodiment
Describe the specific embodiment of the present utility model in detail below in conjunction with technical scheme and accompanying drawing.
This utility model is made up of for three layers catheter body (1), antibiotic layer (2) and hydrophilic layer (3) etc.Wherein antibiotic layer (2) is coated in the outer surface of catheter body (1), at the outer surface coating hydrophilic layer (3) of antibiotic layer (2).Dip-coating mode film forming the most commonly used is adopted in the coating coating.
Antibiotic hydrophilic coating catheter of the present utility model, wherein hydrophilic coating adopts hydrophilic polymer, has self-lubricating function behind the chance water, reduces the frictional resistance when implanting, and is easy to operate, reduces the stimulation to mucous membrane of urethra, can effectively alleviate patient's misery.After catheter implantation back hydrophilic polymer is water-soluble, expose antibiotic layer, the antibacterial action of performance chitin or chitosan, commute cause that antibacterial such as the escherichia coli, staphylococcus aureus, Candida albicans of urethra inflammation has good fungistatic effect, and have lasting antibacterial action.This that antibiotic layer and hydrophilic layer are coated in the structural design of original catheter outer surface successively is simple, easy to use, has antibiotic and lubricated double effects, is patient's Gospel, has also made things convenient for medical personnel.

Claims (3)

1. an antibiotic hydrophilic coating catheter is characterized in that: be made up of catheter body (1), antibiotic layer (2) and hydrophilic layer (3); Wherein antibiotic layer (2) is coated in the outer surface of catheter body (1), at the outer surface coating hydrophilic layer (3) of antibiotic layer (2); Dip-coating mode film forming is adopted in the coating coating.
2. a kind of antibiotic hydrophilic coating catheter according to claim 1, its feature also is: described antibiotic layer (2) is for comprising the coating of chitin and/or chitosan and derivant thereof;
3. a kind of antibiotic hydrophilic coating catheter according to claim 1, its feature also is: described hydrophilic coating is the coating of Polyethylene Glycol, polyvinylpyrrolidone or polyvinylpyrrolidone-vinyl acetate hydrophilic polymer.
CN2009203058013U 2009-07-08 2009-07-08 Catheter with antimicrobial and hydrophilic coatings Expired - Fee Related CN201431691Y (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2009203058013U CN201431691Y (en) 2009-07-08 2009-07-08 Catheter with antimicrobial and hydrophilic coatings

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009203058013U CN201431691Y (en) 2009-07-08 2009-07-08 Catheter with antimicrobial and hydrophilic coatings

Publications (1)

Publication Number Publication Date
CN201431691Y true CN201431691Y (en) 2010-03-31

Family

ID=42050505

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009203058013U Expired - Fee Related CN201431691Y (en) 2009-07-08 2009-07-08 Catheter with antimicrobial and hydrophilic coatings

Country Status (1)

Country Link
CN (1) CN201431691Y (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102973986A (en) * 2012-07-19 2013-03-20 黄斌 Medical super-lubricity antibacterial catheter coating liquid
CN103301552A (en) * 2013-06-20 2013-09-18 南通大学附属医院 Nano composite chitosan antibacterial rubber T-shaped tube and production method thereof
CN104874028A (en) * 2015-04-10 2015-09-02 南京天朗制药有限公司 Super-lubricant antibacterial catheter and preparation method thereof
CN106110404A (en) * 2016-08-11 2016-11-16 成都嘉宝祥生物科技有限公司 The manufacture method of catheter
CN108607151A (en) * 2018-05-21 2018-10-02 青岛杰圣博生物科技有限公司 A kind of antibiotic catheters and preparation method thereof
WO2018219035A1 (en) 2017-05-31 2018-12-06 苏州度博迈医疗科技有限公司 Antimicrobial silicone rubber, preparation method therefor and use thereof
CN111870742A (en) * 2020-06-24 2020-11-03 东南大学 Preparation method of hydrophilic lubricating coating on surface of PVC (polyvinyl chloride) catheter

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102973986A (en) * 2012-07-19 2013-03-20 黄斌 Medical super-lubricity antibacterial catheter coating liquid
CN103301552A (en) * 2013-06-20 2013-09-18 南通大学附属医院 Nano composite chitosan antibacterial rubber T-shaped tube and production method thereof
CN104874028A (en) * 2015-04-10 2015-09-02 南京天朗制药有限公司 Super-lubricant antibacterial catheter and preparation method thereof
CN106110404A (en) * 2016-08-11 2016-11-16 成都嘉宝祥生物科技有限公司 The manufacture method of catheter
WO2018219035A1 (en) 2017-05-31 2018-12-06 苏州度博迈医疗科技有限公司 Antimicrobial silicone rubber, preparation method therefor and use thereof
CN108607151A (en) * 2018-05-21 2018-10-02 青岛杰圣博生物科技有限公司 A kind of antibiotic catheters and preparation method thereof
CN108607151B (en) * 2018-05-21 2021-06-01 青岛杰圣博生物科技有限公司 Antibacterial catheter and preparation method thereof
CN111870742A (en) * 2020-06-24 2020-11-03 东南大学 Preparation method of hydrophilic lubricating coating on surface of PVC (polyvinyl chloride) catheter

Similar Documents

Publication Publication Date Title
CN201431691Y (en) Catheter with antimicrobial and hydrophilic coatings
CN2778285Y (en) Antibacterial super slippery urethral catheter
CN102973986A (en) Medical super-lubricity antibacterial catheter coating liquid
CN100471528C (en) Liquid wound-dressing with functions of promoting heal of wound and bacterial-resisting
KR101725175B1 (en) Antimicrobial composition
WO2012109187A1 (en) Methods and devices for preventing catheter related urinary tract infections
CN101366969B (en) Uses of zinc oxide as reinforcing agent of chitosan biomembrane
CN1823813A (en) Nursing and treating composition for female vagina and its preparation method
CN108158995A (en) A kind of gynaecology's anti-bacteria foaming agent containing chitosan and preparation method thereof
US20220347138A1 (en) Wound care product
US20090227930A1 (en) Hygiene materials and absorbents
US20190099523A1 (en) Film-forming composition for a ph-dependant sustained release of the active agent
CN104740690A (en) Medicine-carrying nano antibacterial super-smooth coating for marine organisms
EP1324785A1 (en) Catheter with hydrophilic coating comprising an anthraquinone
CA2679610A1 (en) Healing powder and method of use thereof
Trautner et al. Prevention of urinary tract infection in patients with spinal cord injury
CN111166932B (en) Liquid wound spray dressing and preparation method thereof
WO2017200818A1 (en) Coatings and methods for infection-resistant medical devices
CN201375746Y (en) Medical antibiosis catheter
WO2022096671A1 (en) Protective device as a temporary sealing means during sexual activities, for preventing inflammation of the urinary tract and bladder
CN204910434U (en) Antibiotic superslide peritoneal cavity drainage tube
CN202682519U (en) Super smooth antibacterial catheter
CN210873230U (en) Catheter with polycation compound coating
US20220370688A1 (en) Urinary catheters and methods for preventing bacterial infections
CN115487226B (en) External natural bactericide pharmaceutical composition

Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100331

Termination date: 20120708