CN201313900Y - Patch clamp constant-temperature device - Google Patents
Patch clamp constant-temperature device Download PDFInfo
- Publication number
- CN201313900Y CN201313900Y CNU200820222317XU CN200820222317U CN201313900Y CN 201313900 Y CN201313900 Y CN 201313900Y CN U200820222317X U CNU200820222317X U CN U200820222317XU CN 200820222317 U CN200820222317 U CN 200820222317U CN 201313900 Y CN201313900 Y CN 201313900Y
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- water
- temperature
- constant
- water tank
- patch clamp
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Abstract
The utility model relates to a medical instrument, in particular to a patch clamp constant-temperature device applied to the patch clamp experiment to enable the patch to be in the constant-temperature environment. The patch clamp constant-temperature device is characterized in that a concave cavity (2) with diameter of 20 centimeters is formed on a patch analysis table (1), a water inlet opening (4) and a water outlet opening (5) of the concave cavity (2) are connected with a water inlet opening (4) and a water outlet opening (5) of a constant-temperature water tank (7) through water pipes in a sealed manner, a miniature water pump (6) is connected between the water inlet opening (4) of the constant-temperature water tank (7) and the water outlet opening (5) of the concave cavity (2), the miniature water pump (6) is connected with a liquid inlet pipe of incubation liquid (3) in a sealing manner, and a heating device (8) is arranged in the constant-temperature water tank (7) and is electrically connected with a control instrument (10). The utility model enables the liquid in the concave cavity to be remained at the desired temperature, and not only reduces the cost, but also is convenient in use.
Description
Technical field
The utility model relates to Medical Instruments, particularly adapts to making diaphragm be in patch clamp thermostat in the homothermic environment in the patch clamp experiments.
Background technology
In brain sheet patch clamp experiments, diaphragm need be placed in the cavity (about 20 centimeters of diameter) of experimental analysis platform central authorities.Brain sheet in the cavity is hatched the liquid circulation-supplied, and will keep constant temp (generally about 30 ℃).Existing thermostat is many by import, and price general charged is about Renminbi 3000-4000 unit.Its principle is to connect heating unit and temperature sensor in the cavity bottom, and heating unit and temperature sensor are electrically connected with monitoring instrument, is in the temperature that needs by the water in the monitoring instrument control cavity.Because cavity is very little, the liquid of being heated is (several milliliters approximately) seldom, for variation of temperature, need temperature sensor and monitoring instrument sensitive and promptly regulate, otherwise can make the interior water temperature variation of cavity greatly, influence the diaphragm-operated activity.We can say that present device had not only cost an arm and a leg and used effect but also desirable not to the utmost.
Summary of the invention
The utility model provides a kind of patch clamp thermostat, can make the interior liquid of cavity remain on the temperature of setting all the time, has both reduced cost greatly, possesses advantage easy to use again.
The purpose of this utility model is to realize like this, the patch clamp thermostat, it is characterized in that: it is 20 centimeters cavity that a diameter is arranged on the diaphragm analysis station, cavity water-in and water outlet are tightly connected by the water-in and the water outlet of water pipe and constant temperature water tank, between the water outlet of the water-in of constant temperature water tank and cavity, be connected to micro pump, micro pump is connected with Incubating Solution fluid inlet pipe tube sealing, and heating unit is arranged in constant temperature water tank, and heating unit is electrically connected with monitoring instrument.
Described cavity internal fixing has temperature sensor, and temperature sensor is electrically connected with monitoring instrument.
Described constant temperature water tank volume is 200 milliliters.
Described constant temperature water tank internal fixing has temperature sensor, and temperature sensor is electrically connected with monitoring instrument.
The utility model utilizes a constant temperature water tank that the constant temperature water source is provided, and the temperature that enters the brain sheet Incubating Solution in the cavity heats by water tank.Water temperature forms closed loop by monitoring instrument according to the temperature control heating unit that temperature sensor detects.And the constant temperature water tank volume approximately is 200 milliliters, keeps the constant of temperature easily, has just kept the constant of the interior fluid temperature of cavity.In addition, the utility model simple structure realizes easily, (about 200 yuan of about Renminbi) with low cost, and volume is small and exquisite, is placed on the use that does not influence other parts on the analysis station, is easy to promote.
Description of drawings
The utility model is described in further detail below in conjunction with the embodiment accompanying drawing.
Fig. 1 is the utility model embodiment 1 structural representation;
Fig. 2 is the utility model embodiment 2 structural representations.
Among the figure: 1, diaphragm analysis station; 2, cavity; 3, Incubating Solution; 4, water-in; 5, water outlet; 6, micro pump; 7, constant temperature water tank; 8, heating unit; 9, temperature sensor; 10, monitoring instrument.
Embodiment
As shown in Figure 1, be provided with a diameter in the diaphragm analysis station 1 at 20 centimeters cavity 2.Brain sheet Incubating Solution 3 in the cavity 2 is by water-in 4, water outlet 5 and micro pump 6 circulation-supplied isothermal liquids.Constant temperature water tank 7 is placed on the diaphragm analysis station 1,200 ml waters are housed in it, heating unit 8 and temperature sensor 9 are in constant temperature water tank 7, heating unit 8 is connected with the control end of temperature sensor 9 with monitoring instrument 10, water under the control of monitoring instrument 10 in the heating unit 8 heated constant temperature water tanks 7 guarantees that water temperature can be constant in design temperature in the constant temperature water tank 7.Monitoring instrument 10 can be regulated design temperature in the constant temperature water tank 7, makes water-in 4 remain on about 30 ℃ through temperature after the constant temperature water tank 7 heating arrival cavitys 2.
As shown in Figure 2, embodiment 2 difference from Example 1 are that temperature sensor 9 is fixed on the bottom of cavity 2, directly detect the water temperature of cavity 2, make the water in the constant temperature water tank 7 keep steady temperature by monitoring instrument 10 control heating units 8 then, the temperature in the assurance cavity 2 is about 30 ℃.
In embodiment 1, water temperature and the water inlet pipe length that enters in the water tank that heating unit 8 is required, the water inlet pipe length between water tank and the cavity 2, factors such as outside temperature are relevant, can estimate by the temperature of measuring in the cavity 2.
Should be too not big during constant temperature water tank 7 designs, should be too not little yet, guarantee the homo(io)thermism of constant temperature water tank 7, diaphragm is in the homothermic environment.The utility model design volume with about 200 milliliters for well.
Claims (4)
1, patch clamp thermostat, it is characterized in that: it is 20 centimeters cavity (2) that a diameter is arranged on the diaphragm analysis station (1), cavity (2) water-in (4) and water outlet (5) are tightly connected by the water-in (4) and the water outlet (5) of water pipe and constant temperature water tank (7), between the water outlet (4) of the water-in (4) of constant temperature water tank (7) and cavity (2), be connected to micro pump (6), micro pump (6) is connected with Incubating Solution (3) fluid inlet pipe tube sealing, heating unit (8) is arranged in constant temperature water tank (7), and heating unit (8) is electrically connected with monitoring instrument (10).
2, patch clamp thermostat according to claim 1 is characterized in that: described cavity (2) internal fixing has temperature sensor (9), and temperature sensor (9) is electrically connected with monitoring instrument (10).
3, patch clamp thermostat according to claim 1 is characterized in that: described constant temperature water tank (7) volume is 200 milliliters.
4, patch clamp thermostat according to claim 1 is characterized in that: described constant temperature water tank (7) internal fixing has temperature sensor (9), and temperature sensor (9) is electrically connected with monitoring instrument (10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU200820222317XU CN201313900Y (en) | 2008-11-06 | 2008-11-06 | Patch clamp constant-temperature device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU200820222317XU CN201313900Y (en) | 2008-11-06 | 2008-11-06 | Patch clamp constant-temperature device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201313900Y true CN201313900Y (en) | 2009-09-23 |
Family
ID=41125692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU200820222317XU Expired - Fee Related CN201313900Y (en) | 2008-11-06 | 2008-11-06 | Patch clamp constant-temperature device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201313900Y (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103320318A (en) * | 2013-07-08 | 2013-09-25 | 西安富康空气净化设备工程有限公司 | Patch clamp constant-temperature system with good temperature control |
| CN104099238A (en) * | 2014-07-10 | 2014-10-15 | 中国人民解放军第四军医大学 | Diaphragm incubation device with controllable temperature and controllable dissolved oxygen |
| CN107765725A (en) * | 2016-08-16 | 2018-03-06 | 中国科学院生物物理研究所 | Patch-clamp low noise temperature control device |
-
2008
- 2008-11-06 CN CNU200820222317XU patent/CN201313900Y/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103320318A (en) * | 2013-07-08 | 2013-09-25 | 西安富康空气净化设备工程有限公司 | Patch clamp constant-temperature system with good temperature control |
| CN103320318B (en) * | 2013-07-08 | 2015-02-11 | 西安富康空气净化设备工程有限公司 | Patch clamp constant-temperature system with good temperature control |
| CN104099238A (en) * | 2014-07-10 | 2014-10-15 | 中国人民解放军第四军医大学 | Diaphragm incubation device with controllable temperature and controllable dissolved oxygen |
| CN107765725A (en) * | 2016-08-16 | 2018-03-06 | 中国科学院生物物理研究所 | Patch-clamp low noise temperature control device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090923 Termination date: 20111106 |