CN201173913Y - Sample storage and sampling system for liquid phase chromatography analysis - Google Patents
Sample storage and sampling system for liquid phase chromatography analysis Download PDFInfo
- Publication number
- CN201173913Y CN201173913Y CNU2008200460378U CN200820046037U CN201173913Y CN 201173913 Y CN201173913 Y CN 201173913Y CN U2008200460378 U CNU2008200460378 U CN U2008200460378U CN 200820046037 U CN200820046037 U CN 200820046037U CN 201173913 Y CN201173913 Y CN 201173913Y
- Authority
- CN
- China
- Prior art keywords
- sample storage
- liquid
- sampling system
- sampling
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Abstract
The utility model discloses a sample storage and inlet system for liquid chromatography analysis. A sample storage system comprises a cuvette, a bubble eliminating pipe and a peristaltic pump of a continuous flow analyzer which are connected in sequence via a pipeline; an inlet system comprises an injection valve of a liquid chromatograph; the injection valve is provided with an injection port which is connected with the peristaltic pump via a pipeline. The sample storage and inlet system realizes the storage and sampling of flowing phase samples from a reaction unit of the continuous flow analyzer for liquid chromatography analysis and carries out bubbles trapping treatment, which can improve the sensitivity of liquid chromatography analysis to ensure the accuracy of the analysis result; the samples after bubble trapping treatment are injected through the injection port of a six-way-valve and waste liquor flows in a waste liquor pipe from an interface of a waste liquor pipe of the six-way-wave and is discharged, being convenient and practical.
Description
Technical field
The utility model belongs to technical field of analysis and detection, is specifically related to a kind of sample storage and sampling system of liquid-phase chromatographic analysis.
Background technology
Liquid-phase chromatographic analysis (LC) is expelled to the form of sample with " plug " in the carrier fluid of certain flow rate one by one by sampling valve, because the effect of convection current diffusion and molecular diffusion, sample is dispersed into the sample band with finite concentration gradient in current-carrying, timing scientific principle opinion according to the dynamic analysis law areas, organically combine sample injection, controlled dispersion, high-precision opportunity reappearing (constant remaining time) three, realize dynamic balance.The repeatability of its analysis depends on conditions such as accurate control sampling volume, flow velocity, constant dispersion degree and temperature, to the requirement height of accuracy of instrument.But simultaneously, the consumption of its sample, reagent has also still less reduced the generation of subsidiary reaction, and has expanded the scope of using.The most important thing is that LC has used the chromatographic resolution principle, adopt polar column or non-polar column that different component is separated.But can not utilize LC to carry out chemical reaction usually.
Continuous Flow Analysis instrument (CFA) chemical reaction units can be finished The pretreatment and various physical-chemical reaction, as carry out sample removal of impurities, distill, clear up, colour developing etc.Simultaneously, the liquid flow point is slit into section one by one owing to introduce air at reagent and sample mix space before, even thereby after the pre-service and various physical-chemical reaction through longer flow process, the dispersion degree of sample is still very little, does not have significantly " aftereffect ".Therefore, treated, reacted sample can import various detecting devices and do next step analysis, for example considers to connect liquid chromatography (LC) instrument.
So the applicant considers to solve the storage of the moving phase sample that Continuous Flow Analysis instrument reaction member flows out and sampling and is used for liquid chromatograph and carries out liquid phase analysis.But, can have a strong impact on the liquid-phase chromatographic analysis result because Continuous Flow Analysis itself has often been sneaked into the bubble that air forms in the moving phase solution that its reaction member flows out; Must consider also that simultaneously the liquid chromatography input mode is that quantitatively the ring sampling valve is injected this situation, need to adopt suitable components that both are connected, acquisition is fit to the quantitatively sample of ring sampling valve sampling, reaches the problem that unnecessary sample is handled that solves.And at present, not seeing has relevant bibliographical information.
The utility model content
The purpose of this utility model is at the deficiencies in the prior art, and a kind of sample storage and sampling system of liquid-phase chromatographic analysis is provided.
The technical solution of the utility model is:
A kind of sample storage and sampling system of liquid-phase chromatographic analysis are provided, and described sample storage system comprises Continuous Flow Analysis instrument colorimetric pool, deaeration pipe and the peristaltic pump that connects successively by pipeline; Described sampling system comprises the chromatographic analyzer of liquid phase sampling valve; Described sampling valve is provided with injection port, and described injection port directly connects peristaltic pump by pipeline.
Described colorimetric pool is de-bubble colorimetric pool or not de-bubble colorimetric pool.
Described deaeration pipe is provided with waste discharge mouth and two links, and a link is connected with colorimetric pool, and another link is connected with peristaltic pump.
Described sampling valve is a six-way valve.Described six-way valve is provided with six channel interfaces, and described channel interface comprises injection port, chromatographic column interface, chromatograph moving phase interface, sewer pipe interface and quantitatively encircles two interfaces.
The beneficial effects of the utility model are: the moving phase sample sample storage that has successfully realized Continuous Flow Analysis instrument reaction member is flowed out is to be used for liquid-phase chromatographic analysis, and can remove bubble and handle, effectively improve liquid-phase chromatographic analysis sensitivity, guarantee precision of analysis; Remove sample after bubble is handled from six-way valve injection port sample introduction, waste liquid flows into sewer pipe through the sewer pipe interface of six-way valve and discharges, and is convenient and practical.
Description of drawings
Fig. 1 connected system synoptic diagram of the present utility model
Fig. 2 six-way injection valve fills the sample view
Fig. 3 six-way injection valve sample introduction view
Embodiment
Further specify the utility model below in conjunction with the drawings and specific embodiments.
As shown in Figure 1, a kind of sample storage of liquid-phase chromatographic analysis and sampling system, described sample storage system comprises Continuous Flow Analysis system colorimetric pool 2, deaeration pipe 3 and the peristaltic pump 5 that connects successively by the sample pipeline; Described sampling system comprises the chromatographic analyzer of liquid phase sampling valve; Described sampling valve is provided with injection port 6, and described injection port directly connects peristaltic pump 5 by pipeline.Colorimetric pool 2 can adopt any one of de-bubble and not de-bubble colorimetric pool.
The sample flow direction is shown in arrow in the accompanying drawing.The sample that flows out through Continuous Flow Analysis instrument (CFA) chemical reaction units 1 flows into deaeration pipes 3 through colorimetric pool 2, and the deaeration pipe is provided with waste discharge mouth 4, all bubbles are discharged, the sample after the processing through peristaltic pump 5 by six-way valve injection port 6 sample introductions.
Six-way valve is the parts that liquid chromatograph carries, also can adopt the similar external six-way valve control of parts principle of work that carries to liquid chromatograph, its valve switching controls is controlled by liquid chromatograph, control operation setting and liquid chromatography routine being provided with when chromatogram bottle is taken a sample is identical, but can only carry out full ring sample introduction.Simultaneously, different with normal liquid chromatography parts connected mode, six-way valve injection port 6 is not connected with the sample introduction pipeline of chromatogram, but is connected to peristaltic pump 5.And the connected mode of all the other interfaces of six-way valve is seen accompanying drawing 2 and accompanying drawing 3: interface 7 is connected chromatographic column, and interface 8 connects the discharging of waste liquid pipe for chromatograph moving phase inlet, interface 9, and interface 9 and interface 10 are two interfaces that quantitatively encircle.Six-way valve is in and fills the sample state as shown in Figure 2, the sample introduction state as shown in Figure 3, the sample that is pumped out by peristaltic pump 5 charges into six-way valve by injection port 6, chromatogram flow phase imports six-way valves by interface 8, is derived by interface 7 at last and enters chromatographic column.
Claims (5)
1, a kind of sample storage of liquid-phase chromatographic analysis and sampling system is characterized in that described sample storage system comprises colorimetric pool, deaeration pipe and the peristaltic pump of the Continuous Flow Analysis instrument that connects successively by pipeline; Described sampling system comprises the chromatographic analyzer of liquid phase sampling valve; Described sampling valve is provided with injection port, and described injection port directly connects peristaltic pump by pipeline.
2,, it is characterized in that described colorimetric pool is de-bubble colorimetric pool or not de-bubble colorimetric pool according to the sample storage and the sampling system of the described liquid-phase chromatographic analysis of claim 1.
3, according to the sample storage and the sampling system of the described liquid-phase chromatographic analysis of claim 1, it is characterized in that described deaeration pipe is provided with waste discharge mouth and two links, a link is connected with colorimetric pool, and another link is connected with peristaltic pump.
4,, it is characterized in that described sampling valve is a six-way valve according to the sample storage and the sampling system of the described liquid-phase chromatographic analysis of claim 1.
5, according to the sample storage and the sampling system of the described liquid-phase chromatographic analysis of claim 4, it is characterized in that described six-way valve is provided with six channel interfaces, described channel interface comprises injection port, chromatographic column interface, chromatograph moving phase interface, sewer pipe interface and quantitatively encircles two interfaces.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200460378U CN201173913Y (en) | 2008-04-07 | 2008-04-07 | Sample storage and sampling system for liquid phase chromatography analysis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200460378U CN201173913Y (en) | 2008-04-07 | 2008-04-07 | Sample storage and sampling system for liquid phase chromatography analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201173913Y true CN201173913Y (en) | 2008-12-31 |
Family
ID=40201041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2008200460378U Expired - Lifetime CN201173913Y (en) | 2008-04-07 | 2008-04-07 | Sample storage and sampling system for liquid phase chromatography analysis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201173913Y (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112362794A (en) * | 2020-11-10 | 2021-02-12 | 山东悟空仪器有限公司 | Sample feeder, full-loop sample feeding method, liquid analysis method and liquid chromatography system |
-
2008
- 2008-04-07 CN CNU2008200460378U patent/CN201173913Y/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112362794A (en) * | 2020-11-10 | 2021-02-12 | 山东悟空仪器有限公司 | Sample feeder, full-loop sample feeding method, liquid analysis method and liquid chromatography system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7347936B2 (en) | Liquid chromatograph | |
| Růžička et al. | Flow injection analysis. principles, applications and trends | |
| CN103235074B (en) | High performance liquid chromatography online analysis method and application thereof | |
| CN101206205B (en) | Method and isolated device for micro flux liquid chromatogram on-line large volume sample injection | |
| CN102262163B (en) | Rapid and automatic determination method and device for tripolycyanamide content in dairy products | |
| CN102650590A (en) | Method for determining content of nitrogen in nitrate and/or nitrite of water sample and device thereof | |
| CN102967495B (en) | Sample pretreatment device and sample treatment method | |
| CN104062170A (en) | Automatic online micro-scale sample dilution and mixing system and mixing method | |
| CN103134889A (en) | On-line enrichment-substep focus sample introduction-ultra-high performance liquid chromatography combination system and application | |
| CN201173913Y (en) | Sample storage and sampling system for liquid phase chromatography analysis | |
| CN201173912Y (en) | Flowing test sample storage and sampling system for liquid phase chromatography analysis | |
| JPS6197567A (en) | Sample preprocessor | |
| CN211877889U (en) | Chromatograph-mass spectrometer | |
| Válcarcel et al. | Coupling continuous sample treatment systems to capillary electophoresis | |
| CN2630850Y (en) | Solid-phase microextraction and liquid-phase chromatographic combined apparatus | |
| CN102323433B (en) | Reagent precise quantitative sample-injection method and system | |
| CN208297540U (en) | A kind of Flow Injection Analysis device for saving reagent solution | |
| CN201173914Y (en) | Continuous flowing analytical reaction unit effluent test sample processing system | |
| CN104062167A (en) | Automatic online sample dilution and mixing device and mixing method | |
| CN203908852U (en) | Automatic online micro sample diluting and mixing system | |
| CN212159315U (en) | Device for automatically enriching red tide toxins in concentrated seawater | |
| CN206489129U (en) | Integral type form and macroanalysis atomic fluorescence sample introduction and pretreatment system | |
| CN201173917Y (en) | Continuous streaming analyzer and liquid phase chromatography analyzer connection system | |
| CN202886166U (en) | Sample pretreatment device | |
| CN201173916Y (en) | Continuous streaming analytical reaction unit effluent test sample storage system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20081231 |