CN201006018Y - Montmorillonite colon positioning releasing tablet - Google Patents
Montmorillonite colon positioning releasing tablet Download PDFInfo
- Publication number
- CN201006018Y CN201006018Y CNU2007200171918U CN200720017191U CN201006018Y CN 201006018 Y CN201006018 Y CN 201006018Y CN U2007200171918 U CNU2007200171918 U CN U2007200171918U CN 200720017191 U CN200720017191 U CN 200720017191U CN 201006018 Y CN201006018 Y CN 201006018Y
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- CN
- China
- Prior art keywords
- colon
- montmorillonite
- insoluble
- utility
- model
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Abstract
The utility model provides a technical scheme for releasing the colon-positioning montmorillonite capsule, which is characterized in that a montmorillonite capsule 1 is wrapped with a PH-independent colon soluble resin foil 2 which is insoluble in the stomach liquid and small intestine liquid. The utility model can avoid releasing drug after taken, to guarantee delivery the quantitative drug into the colon, to increase the curative effect of various cute and chronic loose bowel movements, in particular to colitis in the colon and rectum.
Description
Technical field
This utility model relates to a kind of smectite middle gut location releasing piece, belongs to medical technical field.
Technical background
Montmorillonitum looses as a kind of mucosa protective agent efficiently, and the adsorbent of pathogenic bacteria, virus and toxin thereof is used for the treatment of various acute and chronic diarrhoeal diseasess, high effect nontoxic, now more than 100 countries and regions listing in the whole world.The Montmorillonitum preparation that has now gone on the market also has tablet, suspensoid, granule, dispersible tablet, and they all are ordinary preparations.When being used for the treatment of site of pathological change in the various acute and chronic diarrhoeal diseases of colon and rectum especially colitis, adopt oral or coloclysis, the coloclysis curative effect is significantly better than oral.
Behind the common Montmorillonitum preparation oral, medicine promptly is adsorbed on upper digestive tract before arriving colon or absorption affinity is saturated substantially, thereby relatively poor to the therapeutic effect of colitis; The retention enema administration, drug effect is more oral good, but medicine is at the colon skewness, individual variation is big, and medicine often only can arrive rectum and sigmoid colon, difficult transverse colon and the ascending colon of arriving, this kind route of administration makes the patient very painful simultaneously, and medical worker's burden is also heavy.
Summary of the invention
In order to overcome the various acute and chronic diarrheal deficiency of existing common Montmorillonitum preparation for treating site of pathological change, the utility model proposes a kind of smectite middle gut location releasing piece at colon and rectum.
The technical scheme that its technical problem that solves this utility model adopts is: with Montmorillonitum sheet 1, outsourcing a kind of in gastric juice, intestinal fluid the molten resin film clothing 2 of all insoluble ph dependent form colon.
This utility model beneficial effect and effect are that behind the drug oral, at the little intestinal segment of harmonization of the stomach, because the protection of the molten resin film clothing of ph dependent form colon, medicine does not discharge in the harmonization of the stomach small intestinal, thereby guarantees medicine quantitatively is transported in the colon.When medicine arrived colon, resin was dissolved about 1 hour, begins to discharge medicine.Thereby valid density exceeds several times than ordinary preparation in colon position topical remedy.The local drug concentration height helps more pathogenic bacteria, virus and toxin thereof and is adsorbed fixing and excretes, and more helps strengthening the defense function of local mucosa.So can improve the curative effect of site of pathological change in the various acute and chronic diarrhoea of colon and rectum especially colitis etc.Specificity is higher, and taking convenience again can improve the compliance of extensive patients.
Description of drawings
Accompanying drawing cross-sectional schematic of the present utility model.
The specific embodiment
Be formulated in the molten resin film coating solution of all insoluble ph dependent form colon in gastric juice, the intestinal fluid: take by weighing polyacrylic resin III45g, pour in the ethanol of 1000ml 95%, stir, add dibutyl phthalate (DBP) 3ml, stir, polyacrylic resin III is all dissolved, standby.
With Montmorillonitum sheet 1, put in the coating machine, the film coating method is used in the molten resin film coating solution of all insoluble ph dependent form colon in gastric juice, the intestinal fluid routinely, bag film-coat 2.
Claims (2)
1. the acute and chronic diarrheal smectite middle gut of a treatment location releasing piece is characterized in that Montmorillonitum sheet 1, outsourcing a kind of in gastric juice, intestinal fluid the molten resin film clothing 2 of all insoluble ph dependent form colon.
2. according to the acute and chronic diarrheal smectite middle gut of the described a kind of treatment of claim 1 location releasing piece, it is characterized in that: molten resin film coating 2 main materials of all insoluble ph dependent form colon are polyacrylic resin III in gastric juice, intestinal fluid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200171918U CN201006018Y (en) | 2007-01-11 | 2007-01-11 | Montmorillonite colon positioning releasing tablet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200171918U CN201006018Y (en) | 2007-01-11 | 2007-01-11 | Montmorillonite colon positioning releasing tablet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201006018Y true CN201006018Y (en) | 2008-01-16 |
Family
ID=39001957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2007200171918U Expired - Lifetime CN201006018Y (en) | 2007-01-11 | 2007-01-11 | Montmorillonite colon positioning releasing tablet |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201006018Y (en) |
-
2007
- 2007-01-11 CN CNU2007200171918U patent/CN201006018Y/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: JINAN HONGJITANG PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: JINAN KANGZONG PHARMACEUTICAL R+D CO.,LTD Effective date: 20100511 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 250014 NO.81, QIANFUSHAN EAST ROAD, LIXIA DISTRICT, JINAN CITY, SHANDONG PROVINCE TO: 250100 NO.360, HUALONG ROAD, JINAN CITY HIGH-TECH ZONE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20100511 Address after: 250100 No. 360, Hualong Road, Ji'nan hi tech Development Zone Patentee after: Hongjitang Pharmacy Co., Ltd., Jinan Address before: 250014 No. 81, Shandong Road, thousand Buddha, Lixia District, Ji'nan, Shandong Patentee before: Jinan Kangzhong Medicin Science & Technology Co., Ltd. |
|
| C56 | Change in the name or address of the patentee |
Owner name: SHANDONG HONGJITANG PHARMACEUTICAL GROUP CO., LTD. Free format text: FORMER NAME: HONGJITANG PHARMACY CO., LTD., JINAN |
|
| CP03 | Change of name, title or address |
Address after: 250100 No. 360, Hualong Road, hi tech Zone, Shandong, Ji'nan Patentee after: Shandong Hongjitang Pharmaceutical Co., Ltd. Address before: No. 360, Hualong Road, Ji'nan hi tech Development Zone Patentee before: Hongjitang Pharmacy Co., Ltd., Jinan |
|
| C56 | Change in the name or address of the patentee | ||
| CP03 | Change of name, title or address |
Address after: Licheng District 250103 Shandong city of Ji'nan province by ten Road No. 30766 Patentee after: SHANDONG HONGJITANG PHARMACEUTICAL GROUP CO., LTD. Address before: 250100 No. 360, Hualong Road, hi tech Zone, Shandong, Ji'nan Patentee before: Shandong Hongjitang Pharmaceutical Co., Ltd. |
|
| CX01 | Expiry of patent term |
Granted publication date: 20080116 |
|
| EXPY | Termination of patent right or utility model |