CN1994445A - Spleen-invigorating diarrhea-stopping mixture and preparation process thereof - Google Patents
Spleen-invigorating diarrhea-stopping mixture and preparation process thereof Download PDFInfo
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- CN1994445A CN1994445A CN 200610070308 CN200610070308A CN1994445A CN 1994445 A CN1994445 A CN 1994445A CN 200610070308 CN200610070308 CN 200610070308 CN 200610070308 A CN200610070308 A CN 200610070308A CN 1994445 A CN1994445 A CN 1994445A
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Abstract
The invention discloses a Chinese antidiarrheal mixture for enlivening the spleen and preparation method, wherein the raw materials include (by weight ratio): pilose asiabell root 50-150 parts, white atractylodes rhizome 50-150 parts, atractylodes rhizome 50-150 parts, lotus plumule 50-150 parts, white hyacinth bean 50-150 parts, Chinese yam 100-300 parts, coix seed 100-300 parts, poria cocos wolf 50-150 parts, patchouli 50-150 parts, mace nutmeg 30-90 parts and brown sugar 50-150 parts.
Description
Affiliated technical field
The present invention relates to a kind of herb mixture and preparation method thereof, more specifically is spleen-invigorating diarrhea-stopping mixture and preparation method thereof.
Background technology
Infantile diarrhea is the infant commonly encountered diseases in period, and generation is all arranged throughout the year.Doctor trained in Western medicine is generally given respectively and control infection, fluid therapy and symptomatic treatment in light of the circumstances.It often happens that, and intestinal infection is controlled, and tannalbin, Montmorillonitum loose and use by turns, and infant is still suffered from diarrhoea incessantly.For stool examination fat drop is arranged, western medical treatment gets up powerless only not.This may be relevant with the dysbacteriosis or the improper feeding that use broad ectrum antibiotic to cause.The traditional Chinese medical science is according to clinical symptoms and sign, and dialectical is splenoasthenic diarrhea, controls suitable invigorating the spleen to arrest diarrhea.Although the Chinese patent medicine of invigorating the spleen to arrest diarrhea function is arranged on the medical market, dosage form not too adapts to the taste characteristics of infant, the difficulty so that infant is taken medicine.
Summary of the invention
The objective of the invention is according to theory of Chinese medical science, screened several the spleen strengthening and damp drying, eliminating dampness by diuresis antidiarrheal Chinese medicine is made spleen-invigorating diarrhea-stopping mixture and its preparation method is provided.
The objective of the invention is to realize in the following way:
A kind of spleen-invigorating diarrhea-stopping mixture of the present invention, it is to be made by the following weight proportion raw material:
Radix Codonopsis 50-150 part Rhizoma Atractylodis Macrocephalae 50-150 part Rhizoma Atractylodis 50-150 part
Semen Nelumbinis 50-150 part Semen Lablab Album 50-150 part Rhizoma Dioscoreae 100-300 part
Semen Coicis 100-300 part Poria 50-150 part Herba Pogostemonis 50-150 part
Semen Myristicae 30-90 part brown sugar 50-150 part.
A kind of spleen-invigorating diarrhea-stopping mixture optimum weight ratio range of the present invention is:
100 parts in 100 parts of Semen Nelumbinis of 100 parts of Rhizoma Atractylodis of 100 parts of Rhizoma Atractylodis Macrocephalaes of Radix Codonopsis
100 parts in 200 parts of Poria of 200 parts of Semen Coiciss of 100 portions of Rhizoma Dioscoreaes of Semen Lablab Album
100 parts in 60 portions of brown sugar of 100 parts of Semen Myristicaes of Herba Pogostemonis.
The preparation method of a kind of spleen-invigorating diarrhea-stopping mixture of the present invention may further comprise the steps:
A. select medicine: Radix Codonopsis 50-150 part, Rhizoma Atractylodis Macrocephalae 50-150 part, Rhizoma Atractylodis 50-150 part, Rhizoma Dioscoreae 100-300 part cut into serving pieces, the stripping and slicing of Poria 50-150 part is standby, and the cutting of Herba Pogostemonis 50-150 part is standby; According to the parched with bran method Rhizoma Atractylodis Macrocephalae is fried to coke yellow, Rhizoma Atractylodis are fried to surperficial buff, and Rhizoma Dioscoreae is fried to yellow, and Semen Coicis 100-300 part is fried to little yellow; Semen Lablab Album 50-150 part is fried to little yellow tool focal spot fragmentation according to the method for frying; Lotus seed core removal, fragmentation; Semen Myristicae is simmered system, fragmentation;
B. extract volatile oil: the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Herba Pogostemonis, Semen Myristicae are extracted volatile oil, and standing demix is removed moisture, filters out impurities, and places in the clean container standby;
C. decoct: medicinal residues and Radix Codonopsis, Semen Nelumbinis, Semen Lablab Album, Rhizoma Dioscoreae, Semen Coicis, Poria that the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Herba Pogostemonis, Semen Myristicae are extracted behind the volatile oil decoct twice, adding for the first time 6 times of water gagings decocted 2 hours, add for the second time 6 times of water gagings and decocted 1.5 hours, merge twice decoction liquor and left standstill 12 hours;
D. concentrate: get the supernatant that decocts after leaving standstill, under 85 ℃ of conditions, be concentrated into relative density 1.17～1.19;
E. precipitate with ethanol: get concentrated solution and add ethanol, make to contain the alcohol amount and reach 70%, cold preservation was left standstill 24 hours, got supernatant and reclaimed ethanol to the greatest extent, did not have the alcohol flavor, and under 55 ℃ of conditions, relative density is 1.1 7～1.19;
F. dosing: the clear paste behind the precipitate with ethanol is added purified water boiled 30 minutes, coarse filtration is injected an amount of purified water in addition and is boiled to Agitation Tank in molten sugar bowl, stir and add brown sugar, boiled 30 minutes, coarse filtration is to Agitation Tank, and an amount of purified water of reuse is with in potassium sorbate dissolving and the adding Agitation Tank, add volatile oil, then add an amount of purified water and adjust total amount, make relative density be not less than 1.08, pH value 4.0～6.0, behind the Cryoprecipitation 24 hours, cold filter, canned, sterilization, lamp inspection, encapsulation are promptly.
Function with cure mainly: invigorating the spleen to arrest diarrhea.Be used for children's's chronic diarrhea (spleen-deficient), also can be used for acute having loose bowels (wind-cold type).
Usage: oral.Below 1 year old, a 5ml; 1 year old and more than 1 years old, a 10ml.Every day 3 times.The volt person avoids usefulness in the pathogenic heat.
Medication foundation of the present invention: Radix Codonopsis in the prescription, brown sugar spleen reinforcing and in; Rhizoma Atractylodis Macrocephalae (parched), Rhizoma Atractylodis (parched) the spleen strengthening and damp drying antidiarrheal; Rhizoma dioscoreae (parched), Semen Nelumbinis spleen reinforcing antidiarrheal; Semen Lablab Album (parched), Herba Pogostemonis invigorating the spleen for eliminating dampness antidiarrheal; Semen Coicis, Poria spleen invigorating eliminating dampness by diuresis; Semen Myristicae warming middle-JIAO to promote flow of QI antidiarrheal.According to modern pharmacological research, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Poria all have the enhancing human body immunity function, and Rhizoma Atractylodis, Semen Lablab Album, Poria, Herba Pogostemonis, Semen Myristicae have bacteriostasis concurrently, and Rhizoma Atractylodis, Herba Pogostemonis, Semen Myristicae also have digestion promoting function.All medicines share, and significant invigorating the spleen to arrest diarrhea effect is arranged, and can promote appetite.
The specific embodiment:
Get earlier: Radix Codonopsis 100 grams, the Rhizoma Atractylodis Macrocephalae 100 grams, Rhizoma Atractylodis 100 grams, Semen Nelumbinis 100 grams, Semen Lablab Album 100 grams, Rhizoma Dioscoreae 200 grams, Semen Coicis 200 grams, Poria 100 grams, Herba Pogostemonis 100 grams, Semen Myristicae 60 grams, brown sugar 100 grams.
1. select medicine: standby Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, yam slices, the Poria stripping and slicing is standby, and the Herba Pogostemonis cutting is standby; According to the parched with bran method Rhizoma Atractylodis Macrocephalae is fried to coke yellow, Rhizoma Atractylodis are fried to surperficial buff, and Rhizoma Dioscoreae is fried to yellow, and Semen Coicis is fried to little yellow; Semen Lablab Album is fried to little yellow tool focal spot fragmentation according to the method for frying; Lotus seed core removal, fragmentation; Semen Myristicae is simmered system, fragmentation;
2. extraction volatile oil: the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Herba Pogostemonis, Semen Myristicae are extracted volatile oil, and standing demix is removed moisture, filters out impurities, and places in the clean container standby;
3. decoct: medicinal residues and Radix Codonopsis, Semen Nelumbinis, Semen Lablab Album, Rhizoma Dioscoreae, Semen Coicis, Poria that the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Herba Pogostemonis, Semen Myristicae are extracted behind the volatile oil decoct twice, adding for the first time 6 times of water gagings decocted 2 hours, add for the second time 6 times of water gagings and decocted 1.5 hours, merge twice decoction liquor and left standstill 12 hours;
4. concentrate: get the supernatant that decocts after leaving standstill, under 85 ℃ of conditions, be concentrated into relative density 1.17～1.19;
5. precipitate with ethanol: get concentrated solution and add ethanol, make to contain the alcohol amount and reach 70%, cold preservation was left standstill 24 hours, got supernatant and reclaimed ethanol to the greatest extent, did not have the alcohol flavor, and under 55 ℃ of conditions, relative density is 1.17～1.19;
6. dosing: the clear paste behind the precipitate with ethanol is added purified water boiled 30 minutes, coarse filtration is to Agitation Tank, injecting an amount of purified water in addition in molten sugar bowl boils, stir and add brown sugar 100 grams, boiled 30 minutes, coarse filtration is to Agitation Tank, the an amount of purified water of reuse is with in potassium sorbate 2 gram dissolvings and the adding Agitation Tank, add volatile oil, then adding an amount of purified water adjustment total amount is 1000 milliliters, makes relative density be not less than 1.08, pH value 4.0～6.0, behind the Cryoprecipitation 24 hours, cold filter, canned, sterilization, lamp inspection, encapsulation are promptly.
Clinical observation on the therapeutic effect:
1. infantile diarrhea disease, through doctor trained in Western medicine control infection, fluid infusion, use diarrhea treatment people more than person's 112 examples of suffering from diarrhoea, Chinese medical discrimination is a splenoasthenic diarrhea, gives the treatment of this mixture, very fast recovery from illness 98 examples, 14 examples that take a turn for the better, total effective rate is 100%, infant appetite increases simultaneously.
2. infantile diarrhea disease, without western medical treatment person 22 examples, Chinese medical discrimination is that wind and cold rushes down, and gives the treatment of this mixture, very fast recovery from illness 18 examples, 3 examples that take a turn for the better, invalid 1 example, total effective rate is 95%.
Claims (3)
1. spleen-invigorating diarrhea-stopping mixture is characterized in that it is to be made by the following weight proportion raw material:
Radix Codonopsis 50-150 part Rhizoma Atractylodis Macrocephalae 50-150 part Rhizoma Atractylodis 50-150 part
Semen Nelumbinis 50-150 part Semen Lablab Album 50-150 part Rhizoma Dioscoreae 100-300 part
Semen Coicis 100-300 part Poria 50-150 part Herba Pogostemonis 50-150 part
Semen Myristicae 30-90 part brown sugar 50-150 part.
2. spleen-invigorating diarrhea-stopping mixture as claimed in claim 1 is characterized in that it is to be made by the following weight proportion raw material:
100 parts in 100 parts of Semen Nelumbinis of 100 parts of Rhizoma Atractylodis of 100 parts of Rhizoma Atractylodis Macrocephalaes of Radix Codonopsis
100 parts in 200 parts of Poria of 200 parts of Semen Coiciss of 100 portions of Rhizoma Dioscoreaes of Semen Lablab Album
100 parts in 60 portions of brown sugar of 100 parts of Semen Myristicaes of Herba Pogostemonis.
3. the preparation method of spleen fortifying food digesting mixture as claimed in claim 1 is characterized in that comprising the steps:
A. select medicine: Radix Codonopsis 50-150 part, Rhizoma Atractylodis Macrocephalae 50-150 part, Rhizoma Atractylodis 50-150 part, Rhizoma Dioscoreae 100-300 part cut into serving pieces, the stripping and slicing of Poria 50-150 part is standby, and the cutting of Herba Pogostemonis 50-150 part is standby; According to the parched with bran method Rhizoma Atractylodis Macrocephalae is fried to coke yellow, Rhizoma Atractylodis are fried to surperficial buff, and Rhizoma Dioscoreae is fried to yellow, and Semen Coicis 100-300 part is fried to little yellow; Semen Lablab Album 50-150 part is fried to little yellow tool focal spot fragmentation according to the method for frying; Lotus seed core removal, fragmentation; Semen Myristicae is simmered system, fragmentation;
B. extract volatile oil: the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Herba Pogostemonis, Semen Myristicae are extracted volatile oil, and standing demix is removed moisture, filters out impurities, and places in the clean container standby;
C. decoct: medicinal residues and Radix Codonopsis, Semen Nelumbinis, Semen Lablab Album, Rhizoma Dioscoreae, Semen Coicis, Poria that the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Herba Pogostemonis, Semen Myristicae are extracted behind the volatile oil decoct twice, adding for the first time 6 times of water gagings decocted 2 hours, add for the second time 6 times of water gagings and decocted 1.5 hours, merge twice decoction liquor and left standstill 12 hours;
D. concentrate: get the supernatant that decocts after leaving standstill, under 85 ℃ of conditions, be concentrated into relative density 1.17～1.19;
E. precipitate with ethanol: get concentrated solution and add ethanol, make to contain the alcohol amount and reach 70%, cold preservation was left standstill 24 hours, got supernatant and reclaimed ethanol to the greatest extent, did not have the alcohol flavor, and under 55 ℃ of conditions, relative density is 1.17～1.19;
F. dosing: the clear paste behind the precipitate with ethanol is added purified water boiled 30 minutes, coarse filtration is injected an amount of purified water in addition and is boiled to Agitation Tank in molten sugar bowl, stir and add brown sugar, boiled 30 minutes, coarse filtration is to Agitation Tank, and an amount of purified water of reuse is with in potassium sorbate dissolving and the adding Agitation Tank, add volatile oil, then add an amount of purified water and adjust total amount, make relative density be not less than 1.08, pH value 4.0～6.0, behind the Cryoprecipitation 24 hours, cold filter, canned, sterilization, lamp inspection, encapsulation are promptly.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2006100703089A CN100443107C (en) | 2006-11-15 | 2006-11-15 | Spleen-invigorating diarrhea-stopping mixture and preparation process thereof |
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| CNB2006100703089A CN100443107C (en) | 2006-11-15 | 2006-11-15 | Spleen-invigorating diarrhea-stopping mixture and preparation process thereof |
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| CN1994445A true CN1994445A (en) | 2007-07-11 |
| CN100443107C CN100443107C (en) | 2008-12-17 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698139A (en) * | 2012-06-26 | 2012-10-03 | 陈慧婷 | Dangshen Chinese medicinal preparation for treating hypersomnia and preparation method thereof |
| CN103041278A (en) * | 2013-01-15 | 2013-04-17 | 长治市郊区黄碾镇中心卫生院 | Medicament for treating diarrhea for children |
| CN103520686A (en) * | 2013-10-21 | 2014-01-22 | 邓鑫 | Medicine for curing diarrhea caused by acquired immune deficiency syndrome |
| CN104435533A (en) * | 2014-11-11 | 2015-03-25 | 成都果睿医药科技有限公司 | Codonopsis-containing pharmaceutical composition for treating diarrhea |
| CN104645137A (en) * | 2015-03-05 | 2015-05-27 | 于巧媛 | Traditional Chinese medicine for treating scouring disease caused by spleen deficiency |
| CN108379537A (en) * | 2018-05-09 | 2018-08-10 | 丛念滋 | A kind of infant's invigorating the spleen to arrest diarrhea herbaceous plant drink |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100515408C (en) * | 2005-07-28 | 2009-07-22 | 江西汇仁药业有限公司 | Zisheng fast dispersion solid preparation and its preparation method |
| CN100515407C (en) * | 2005-07-28 | 2009-07-22 | 江西汇仁药业有限公司 | Spleen-tonifying Zisheng fast dispersion solid preparation and its preparation method |
| CN1824215A (en) * | 2005-12-15 | 2006-08-30 | 北京阜康仁生物制药科技有限公司 | Poria ovate attractylodes medicinal preparation and its new preparation method |
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2006
- 2006-11-15 CN CNB2006100703089A patent/CN100443107C/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698139A (en) * | 2012-06-26 | 2012-10-03 | 陈慧婷 | Dangshen Chinese medicinal preparation for treating hypersomnia and preparation method thereof |
| CN102698139B (en) * | 2012-06-26 | 2013-08-28 | 陈慧婷 | Dangshen Chinese medicinal preparation for treating hypersomnia and preparation method thereof |
| CN103041278A (en) * | 2013-01-15 | 2013-04-17 | 长治市郊区黄碾镇中心卫生院 | Medicament for treating diarrhea for children |
| CN103520686A (en) * | 2013-10-21 | 2014-01-22 | 邓鑫 | Medicine for curing diarrhea caused by acquired immune deficiency syndrome |
| CN103520686B (en) * | 2013-10-21 | 2015-09-09 | 邓鑫 | A kind of medicine for the treatment of acquired immune deficiency syndrome (AIDS) diarrhoea |
| CN104435533A (en) * | 2014-11-11 | 2015-03-25 | 成都果睿医药科技有限公司 | Codonopsis-containing pharmaceutical composition for treating diarrhea |
| CN104645137A (en) * | 2015-03-05 | 2015-05-27 | 于巧媛 | Traditional Chinese medicine for treating scouring disease caused by spleen deficiency |
| CN108379537A (en) * | 2018-05-09 | 2018-08-10 | 丛念滋 | A kind of infant's invigorating the spleen to arrest diarrhea herbaceous plant drink |
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| CN100443107C (en) | 2008-12-17 |
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Granted publication date: 20081217 Termination date: 20111115 |