CN1957979A - Medication with effect of being sobered up from wine and protecting liver, and method for making up preparation - Google Patents
Medication with effect of being sobered up from wine and protecting liver, and method for making up preparation Download PDFInfo
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- CN1957979A CN1957979A CN200610083811.8A CN200610083811A CN1957979A CN 1957979 A CN1957979 A CN 1957979A CN 200610083811 A CN200610083811 A CN 200610083811A CN 1957979 A CN1957979 A CN 1957979A
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Abstract
A Chinese medicine in the form of effervescent tablet, particle infusion, capsule, oral liquid, chewing tablet, or buccal lozenge for sobering up and protecting liver is prepared from cress, pueraria flower and liquorice root. Its preparing process is also disclosed.
Description
Technical field
The present invention relates to a kind of is monarch drug with the Herba Oenanthes Javanicae, has the Chinese herbal medicine formula of effects of relieving alcoholism and protecting liver, and reaching with this prescription is the pharmaceutical preparation of raw material.
Background technology
Excessive drinking has become serious day by day problem in countries in the world, WHO points out in the portion report: " alcoholism is first public hazards in world today's scope, and its toxicity can add up the whole body main organs, to having the greatest impact of liver ".At present doctor trained in Western medicine is to adopting quiet notes or intramuscular injection 50% glucose because of the treatment of the acute alcoholism due to drinking, and prevention, treatment alcoholic liver disease and health care are after drinking suffered for want of medical supplies, and developing Medicament for Alcoholism from Chinese medicine has great potential.
Summary of the invention:
The invention reside in the Chinese herbal medicine formula that discloses a kind of relieving alcoholism, dispelling alcohol effects and protecting liver; Another object of the present invention is that open is the pharmaceutical preparation and the liver-protecting sobering up effect thereof of raw material with this prescription.
Chinese herbal medicine formula of the present invention:
With Herba Oenanthes Javanicae, Flos puerariae lobatae and Radix Glycyrrhizae is raw material, is by weight percentage: Herba Oenanthes Javanicae 50-60%, Flos puerariae lobatae 30-40%, Radix Glycyrrhizae 10-20%.
Prescription of the present invention can be made effervescent tablet, dissolved granule, capsule, oral liquid, chewable tablet or buccal tablet, six kinds of dosage forms of beverage by the common process preparation method.
Chinese herbal medicine formula medicine of the present invention has effects of relieving alcoholism and protecting liver, is pure Chinese medicinal preparation, has no side effect.
Following experimental example is used to further specify the present invention, but does not limit the present invention in any way.
Experimental example 1
Table 1 couple mice serum ALT, AST, the influence of liver SOD activity and MDA content (x ± s, n=10)
| Group | Dosage | ALT(nmol·s -1/ L) | AST(nmol·s -1/L) | SOD (Umg) albumen | MDA (μ molg) albumen |
| The blank group | 30% glucose | 430.2±101.3 | 561.1±59.5 | 3.06±0.19 | 56.5±2.87 |
| Model group | 8g/kg | 601.0±56.2d | 748.2±110.7d | 2.49±0.36d | 64.1±2.69d |
| Positive controls | 0.3g/kg+8g/kg | 477.6±73.5b | 651.3±89.0a | 2.93±0.38a | 60.6±2.87a |
| 0.99g/kg+8g/kg | 455.2±88.9b | 602.2±105.6b | 3.12±0.32b | 59.6±3.29a | |
| 0.49g/kg+8g/kg | 459.9±98.1b | 612.9±81.8b | 3.02±0.31b | 60.7±2.32a | |
| 0.25g/kg+8g/kg | 489.3±109.4a | 641.3±80.4a | 2.93±0.37a | 62.3±3.06a |
With model group ratio, a:P＜0.05, b:P＜0.01; With blank group ratio, d:P＜0.01
As shown in Table 1, this prescription can suppress to irritate stomach ethanol mice ALT, AST and raise, and obviously reduces the liter of the MDA content due to the ethanol, reverse the active reduction of Mus liver SOD due to the ethanol, and the amount of having relies on trend; The curative effect of positive drug bartender liver is in Sobering up extraction, between the dosage group.
Experimental example 2:
The preparation of capsule
This prescription extract raw material 100g, medical starch 100g
This prescription extract and medical starch are crossed 100 mesh sieves respectively, and mix homogeneously, an amount of alcohol granulation used.In 60 ℃ of dryings, granulate incapsulates.
The preparation of tablet
This prescription extract raw material 100g, medical starch 100g
This prescription extract and medical starch are crossed 100 mesh sieves respectively, and mix homogeneously, an amount of alcohol granulation used.In 60 ℃ of dryings, through pelletizing machine granulate, tabletting.
The preparation of granule
This prescription extract raw material 100g, medical starch 100g, Icing Sugar 40g
This prescription extract, medical starch and Icing Sugar are crossed 100 mesh sieves respectively, and mix homogeneously, an amount of alcohol granulation used.In 60 ℃ of dryings, granulate, packing.
The preparation of injection
This prescription extract raw material 10g, propylene glycol 20ml, Polyethylene Glycol-400 50ml, water for injection 300ml mixes heating in water bath 30min, add benzyl alcohol 50ml, reuse water for injection adds to 1000ml, handles 10min in ultrasound wave, heats 30min again in water-bath, transfer pH value 5.5-6.5, filter clear and bright, embedding, the sterilization promptly.
Claims (3)
1, a kind of Chinese herbal medicine formula of Antialcoholic liver-protecting is characterized in that: with Herba Oenanthes Javanicae, Flos puerariae lobatae and Radix Glycyrrhizae is raw material, is by weight percentage: Herba Oenanthes Javanicae 50-60%, Flos puerariae lobatae 30-40%, Radix Glycyrrhizae 10-20%.
2, can make effervescent tablet, dissolved granule, capsule, oral liquid, chewable tablet or buccal tablet, six kinds of dosage forms of beverage by the common process preparation method as claim 1 described Chinese herbal medicine formula.
3, Chinese herbal medicine formula medicine of the present invention has effects of relieving alcoholism and protecting liver, is pure Chinese medicinal preparation, has no side effect.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610083811.8A CN1957979A (en) | 2006-06-02 | 2006-06-02 | Medication with effect of being sobered up from wine and protecting liver, and method for making up preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610083811.8A CN1957979A (en) | 2006-06-02 | 2006-06-02 | Medication with effect of being sobered up from wine and protecting liver, and method for making up preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1957979A true CN1957979A (en) | 2007-05-09 |
Family
ID=38069931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200610083811.8A Pending CN1957979A (en) | 2006-06-02 | 2006-06-02 | Medication with effect of being sobered up from wine and protecting liver, and method for making up preparation |
Country Status (1)
| Country | Link |
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| CN (1) | CN1957979A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104585658A (en) * | 2015-01-09 | 2015-05-06 | 李柏松 | Sandwich hawthorn with function of dispelling effects of alcohol, and preparation method of sandwich hawthorn |
| CN104840625A (en) * | 2015-05-28 | 2015-08-19 | 福建中医药大学 | Liver-protecting pharmaceutical composition, and preparation method and use thereof |
| CN104957703A (en) * | 2015-06-30 | 2015-10-07 | 杨华 | Anti-alcoholism beverage and manufacturing method thereof |
| CN108576543A (en) * | 2017-12-25 | 2018-09-28 | 合肥工业大学 | A kind of lower hyperlipidemia, hypertension, hyperglycemia type Chinese celery solid beverage product and preparation method thereof |
-
2006
- 2006-06-02 CN CN200610083811.8A patent/CN1957979A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104585658A (en) * | 2015-01-09 | 2015-05-06 | 李柏松 | Sandwich hawthorn with function of dispelling effects of alcohol, and preparation method of sandwich hawthorn |
| CN104840625A (en) * | 2015-05-28 | 2015-08-19 | 福建中医药大学 | Liver-protecting pharmaceutical composition, and preparation method and use thereof |
| CN104840625B (en) * | 2015-05-28 | 2019-06-11 | 福建中医药大学 | A kind of medicinal composition for protecting liver and its preparation method and application |
| CN104957703A (en) * | 2015-06-30 | 2015-10-07 | 杨华 | Anti-alcoholism beverage and manufacturing method thereof |
| CN108576543A (en) * | 2017-12-25 | 2018-09-28 | 合肥工业大学 | A kind of lower hyperlipidemia, hypertension, hyperglycemia type Chinese celery solid beverage product and preparation method thereof |
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Open date: 20070509 |