CN1957888A - Beautification product for local increasing volume of own body fat without toxin and side effect, and preparation method - Google Patents

Abstract

A skin-beautifying product without toxic by-effect for synthesis and storage of local fat and preventing wrinkles is prepared from vitamin composition and trace element composition. Its preparing process is also disclosed.

Description

Have no side effect local increasing volume from body fat and beautifying face product and manufacture method

Technical field: the invention belongs to cosmetics and production thereof, application.

Background technology: adult and middle-aged and elderly people be subjected to " three-hypers " be in the harm of diseases of cardiovascular and cerebrovascular systems such as hyperglycemia, hypertension, hyperlipidemia and the body depot fat too much or its metabolism bad promptly fat direct and closely related, to this, existing investigation confirm to show the daily dietary fat of China especially animal fat exceed standard, cause over nearly 10 years the chronic diseases in China M ﹠ M to rise rapidly and become rejuvenation trend, as present China adult hypertension prevalence is 18.8%, and the estimation whole nation now trouble number is 1.6 hundred million; Adult's dyslipidemia prevalence is 18.6%, estimates that national dyslipidemia now suffers from number 1.6 hundred million; The overweight rate of being grown up is 22.8%, and obesity rates is 7.1%, estimates that the existing overweight and fat number in the whole nation is respectively more than 200,000,000 and 6,000 ten thousand.China Disease Control and Prevention Center is prediction and warning therefore: as not taking effective Preventing Countermeasures, will having up to more than one hundred million Chinese in 10 years from now on and die from hypertension, hypercholesterolemia, diabetes, obesity, cancer chronic diseases.The archaism cloud: " man is that intimate person is dead, the woman is intimate person's appearance ", so women colony goes after like a flock of ducks especially to fat-reducing; Because the development and the progress of society, social and many male self to traditional male with thick spacious serve as beautiful and sophisticated aesthetic conceptions are taken exception to then advocated good health and a long life and add the main forces' ranks of losing weight with proceeding without hesitation, and the development of this trend advances swiftly unhindered, thereby makes fat-reducing become social fashion's main flow rapidly and obviously present flourishing long time general trend.Yet things all have positive and negative two aspects need compatible with take into account, otherwise lose more than gain even can go to extremes, the end that appears in the newspapers as usual is no lack of the report that is possessed by the Devil even therefore gets killed because of fat-reducing, the sign of making us holding one's own wrist.Just because of this, influence surface that the present invention aims at taking into account, balance and solving relates in this class problem and crowd be some main flow problem and principal contradiction greatly.

In sum and in conjunction with investigation practice and result that social practical situation carries out, it is evident that: a pair of contradiction of this field maximum is lost weight and to cause mastatrophy to be lost most important beautiful because of fat-reducing for beautiful no more than the women at present.Ma Lilian. Ya Long says in " history of breast ": " about breast, the baby sees be food, man see what be that sexual love, doctor see is the money that disease, businessman see "." breast is this most beautiful in the world ' mountain peak ' ", but but be enough to make woman's beautiful even life precarious, be accompanied by women's all one's life.This factor to two aspects of contradiction is that obesity provides sufficient fat to make breast full and plentiful and because of the high and fat relevant growth of safeguarding and strengthening breast of estrogen level makes breast more plentiful more lasting on the one hand, but to emit obesity and bring out cyclomastopathy in addition breast carcinoma to the significant damage threat risk of beautiful and life; Then be to change high fat diet on the other hand, control appetite and body weight are promptly lost weight, but this hardly may the merciless repeatedly already proof of the fact for the fat women of the overwhelming majority, can accomplish that just right winner is very few especially, because well-knownly can go beyond for a long time and keep such as almost rare people of serial difficulty such as " bounce-backs ", provide enough fat to be difficult to maintain the plentiful of breast to breast and remove the state basic policy overwhelming majority that especially has one child per couple of short duration age of sucking for a long time because of body is unable for NO women, often post great expectations in all kinds of breast enlargement products or operation for this reason, can nearly all be " glad; as to come back disappointed ", even to disable be rare yet, cost of paying and consequence are very heavy and irreversible.Reason is also very simple in fact: combining and to return this series products or operation at present, is nothing but that foreign body such as silica gel or autologous fat are put pad or for oral administration and external (smearing) medicine (mostly be hormones or contain hormones) stimulates breast and makes breast enlargement tall and straight to stimulate physical methods such as cyclomastopathy or similar massage, ray; But conspicuous serial adverse consequences is respectively: foreign body is put inhomogeneous, easily transposition bursts report or produces rejection etc. as diving etc. with breaking even burst breast, and is difficult to repair and takes out and follow the painful and risk that disables of new operation fully; It is a good selection comparatively speaking that autologous fat is put, but but fat can be by body constantly and promptly transport breast and in breast, constantly degraded and need constantly to replenish own fat and the position is provided and fatty reserves always limited, and take out, greasing is especially constantly taken out, the misery of greasing, risk and sequela and also can not regard as unimportant to subside hematocele and its additive effect and consequence and misery etc. of infringement attractive in appearance such as liposuction position, so feasibility also be extremely limited, at least be difficult to persistent; Comprise that as for the hormone of oral administration and externally or the medicine that contains hormones the Chinese medicine consequence is then more serious: can cause endocrine regulation, irregular menstruation and aforesaid cyclomastopathy and breast carcinoma etc., though great majority are cyclomastopathy and the not canceration of most of cyclomastopathy promptly is benign, but many need excisions are also arranged and have a strong impact on beauty treatment, go back on one's original intentions on the contrary, and the galactophore epithelial cell variation that form takes place to a certain degree on exuberant basis causes the atypical hypertrophy relevant with the danger of breast carcinoma promptly easily to cause breast carcinoma, and cyclomastopathy and breast carcinoma may exist simultaneously and incur loss through delay detecting and treating of breast carcinoma sometimes, and consequence will be more serious; Physiotherapys such as massage are just like " the cleverest housewife can't cook a meal without rice ", because of its principle only is to improve blood flow in the hope of being with nutrients such as staying some fat in breast more more, but this must be constantly to carry out just having positive effect in some months, only depend on every day or of short duration massage of a few days etc. absolutely void, because only depending on the retention of nutrient substance such as food fat is continuous and very long process, and " fat-reducing " health does not have superabundant fats, can be compared to water without a source, like a tree without roots, massage waits in any case all can not too many practical significance and effect; Massage so why etc. that physiotherapy seems and effectively of short duration and effect " well " sometimes, answer is also very simple: this only is that excessively massage waits the undermined swelling of breast (illusion of the excessive congested water-filling retention of mammary gland) that causes, obviously and the fact prove repeatedly after the detumescent all as usual, effect far from, if leave no choice but have " effect ", that is exactly down to damage breast and mammary gland normal configuration and function for a long time even cause the pathological changes serious consequence.

Goal of the invention: the present invention is exactly for addressing the above problem the local increasing volume that has no side effect that designs from body fat and beautifying face product and manufacture method, and existing main scientific and technological principle and innovation with its foundation is that advantage is described below:

VB ₁Shortage is obstructed sugar (acetone acid) metabolism energy supply, is that non-fat heat energy reduces, must increase fat and energy supply consumption, unfavorable to increasing fat locally purpose of the present invention; VB ₂With VB ₁Equally in close relations with the non-fat heat energy metabolism, shortage can cause that also energy metabolism is disorderly and various clinical symptom such as angular cheilitis, seborrheic dermatitis etc. occur; VB ₆Simultaneously with albumen, fat, carbohydrate metabolism is in close relations and increase VB, VB ₂Curative effect, shortage cause the substance metabolism disorder to weaken with balanced capacity; VC promotes collagen protein synthesis and cholesterol drainage, be beneficial to weight gaining position and even whole skin, the anti crease and anti senile prepared beauty treatment of organ and prevent atherosclerosis, the more important thing is because of the reduction of cholesterol reduces the estrogen synthesis cholesterol has positive correlation (cholesterol is changed by lipometabolic S-acetyl-coenzyme-A) with fat, thus avoid the weight gaining part because of the canceration risk of estrogen increase and balance insulin (stating as follows) to the synthetic promotion of cholesterol and c-AMP to the synthetic inhibitory action of cholesterol; Chromium promote to be beneficial to lipogenesis with stable insulin function, be beneficial to the synthetic and stable of increasing fat locally fat, chromium also balance estrogen raw material serum cholesterol, be beneficial to stablizing of estrogen level; Magnesium is the important cofactor of fat (acid) synzyme, and copper promotes collagen protein synthesis, so and VC synergism and strengthen effect mutually each other.

Embodiment of the present invention:

The present invention is by compound vitamin 0.01-0.1 part, VB wherein ₁0.1-0.3 part, VB ₂0.1-0.3 part, VB ₆0.1-0.3 part, VC 1-3 part, when other material that adopts GB2760 or GB14880 to allow replaces, should convert by active substance; Compound microelement 0.001-0.01 part, wherein potassium dichromate 0.01-0.03 part, magnesium stearate 1-3 part, copper gluconate 0.01-0.03 part are when other material that adopts GB2760 or GB14880 to allow replaces, should form by the active substance conversion.

The manufacture method of product of the present invention is as follows:

The preparation of compound vitamin is got VB in sterilizing room ₁0.1-0.3 part, VB ₂0.1-0.3 part, VB ₆0.1-0.3 part, VC 1-3 part, in nonmetal mortar, grind 3-5 minute standby;

The preparation of compound microelement is got potassium dichromate 0.01-0.03 part, magnesium stearate 1-3 part, copper gluconate 0.01-0.03 part in sterilizing room, in nonmetal mortar, grind 3-5 minute standby;

The preparation of product of the present invention is got compound vitamin 0.01-0.1 part, compound microelement 0.001-0.1 part in sterilizing room, join in the nonmetallic vessel of belt stirrer, 30-60 rev/min stirred in 3-5 minute product.

The purposes of product of the present invention, usage and consumption: as increasing fat locally agent such as medical preparation for making breast plump; The usage breast enlargement is external; Every newborn three times of consumption external every day, each 3-5 milligram.

Embodiment:

1, in sterilizing room, press compound vitamin 0.01 gram, compound microelement 0.001 gram, the proportionate relationship amount of getting that sterilized water is 10 milliliters, join in the nonmetallic vessel of belt stirrer, 30-60 rev/min stirred in 3-5 minute, concentration is about 1 mg/ml, press 3-5 milliliter/specification encapsulation, breast enlargement external, disposable use, before the Kaifeng if any broken or Kaifeng use the back if any residue all make discard processing, to guarantee safety.Other products can be with reference to present embodiment concentration.

2, in sterilizing room, get 0.1 part of compound vitamin, 0.01 part of compound microelement, join in the nonmetallic vessel of belt stirrer, 30-60 rev/min stirred in 3-5 minute, was used as host and the main effect material of producing the breast enlargement product.

Animal experiment and result and explanation and prompting:

Animal (rat) toxic and side effects and increasing fat locally-breast enlargement contrast experiment and method:

Acute toxicological experiment	The per os rat of feeding, 2 gram/kg/day are 1 totally month, no any unusual.
		The sub-acute toxicity experiment	The per os rat of feeding, 1 gram/kg/day is 2 totally months, no any unusual.
Chronic toxicological experiment	The per os rat of feeding, 0.5 gram/kg/day is 3 totally months, no any unusual.
		Side effect (sticking allergy) experiment	The classical rabbit basal part of the ear sticks experiment, 10 days, does not have irritated (any reactions such as redness, incrustation, heating).
Increasing fat locally-breast enlargement contrast experiment	It is plentiful February to be coated with 0.5 milligram/kg body weight/day of this product the breast group of going on a diet, the matched group atrophy of going on a diet of no this product.

Illustrate: 1, trial target is 100% original.2, per 20 of rat is one group, and experiment respectively feeds intake with feed for 3 times every day.3, because of about 900 days of rat average life, event are equivalent to human in March, 10, be enough to as validation criteria.4, animal experiment is up to 40 examples, and the tool animal replaces clinical trial reference statistical meaning, routinely tool proof property and proof.

Prompting: evidence product safety of the present invention, effect are rapidly, significantly and stable.

Claims (3)

1, a kind of local increasing volume that has no side effect is from body fat and beautifying face product, by compound vitamin 0.01-0.1 part, VB wherein ₁0.1-0.3 part, VB ₂0.1-0.3 part, VB ₆0.1-0.3 part, VC 1-3 part, when other material that adopts GB2760 or GB14880 to allow replaces, should convert by active substance; Compound microelement 0.001-0.01 part, wherein potassium dichromate 0.01-0.03 part, magnesium stearate 1-3 part, copper gluconate 0.01-0.03 part are when other material that adopts GB2760 or GB14880 to allow replaces, should form by the active substance conversion.

2, the described local increasing volume that has no side effect of claim 1 is as follows from the manufacture method of body fat and beautifying face product:

The preparation of a compound vitamin is got VB in sterilizing room ₁0.1-0.3 part, VB ₂0.1-0.3 part, VB ₆0.1-0.3 part, VC 1-3 part, in nonmetal mortar, grind 3-5 minute standby;

The preparation of b compound microelement is got potassium dichromate 0.01-0.03 part, magnesium stearate 1-3 part, copper gluconate 0.01-0.03 part in sterilizing room, in nonmetal mortar, grind 3-5 minute standby;

C have no side effect local increasing volume from the preparation of body fat and beautifying face product in sterilizing room, get compound vitamin 0.01-0.1 part, compound microelement 0.001-0.01 part, join in the nonmetallic vessel of belt stirrer, 30-60 rev/min of 3-5 stir in dividing product.

3, the described purposes of local increasing volume that have no side effect of claim 1: external breast enlargement, every newborn three times of consumption every day, each 3-5 milligram from body fat and beautifying face product.