CN1943704A - A Chinese traditional medicinal composition and its preparation method - Google Patents

A Chinese traditional medicinal composition and its preparation method Download PDF

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CN1943704A
CN1943704A CN 200510105961 CN200510105961A CN1943704A CN 1943704 A CN1943704 A CN 1943704A CN 200510105961 CN200510105961 CN 200510105961 CN 200510105961 A CN200510105961 A CN 200510105961A CN 1943704 A CN1943704 A CN 1943704A
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radix
weight portion
water
polygoni multiflori
fine powder
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刘国飞
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Abstract

This invention provides a Chinese traditional medicinal composition for treatment of dryness alopecia psoriasis and alopecia areata. It is prepared by using prepared adhesive rehmannia root(prepared),fleeceflower root, adhesive rehmannia root, Japanese cornel dogwood, yerbadetajo herb, Common yam, Chinese arborvitae leafy twig, ginseng root, pilose asiabell root, peony root bark, oriental waterplantain rhizome, common anemarrhena rhizome, Chinese qolfberry bark,starwort root, etc. It has obvious cruative effect in treating dryness alopecia psoriasis and alopecia areata. It also reveals preparing method.

Description

A kind of Chinese medicine composition and preparation method thereof
Technical field
The present invention relates to treat the drug regimen and the preparation method of dryness seborrheic alopecia and alopecia areata, belong to the field of Chinese medicines.
Background technology
Head is the meeting of hundred sun, the hair hair is the sign of blood condition, and it is dry that wind is contained blood, the blood deficiency of suffering from a deficiency of the kidney, insufficiency of vital energy and blood, can not up honor send out, sending out becomes homeless supports then alopecia, by to local vascular dilation, promotes to improve blood microcirculation, reach nourishing blood to expel wind, eliminating heat from the lung, removing pathogenic heat from blood and toxic substance from the body, YIN nourishing and blood are supported flourish sending out.
Chinese medicine is thought " the kidney being the origin of congenital constitution ", " root of life ".The growth of human body, growth, aging are decided by the prosperity and decline of kidney vital essence, and the maturation of men and women's reproductive function is so that decline also is the vital essence based on kidney.Kidney essense belongs to cloudy, and therefore the kidney QI belonging to YANG claims that kidney essense is a kidney yin; Kidney qi is a kidney yang.Kidney yin is the basic of the cloudy liquid of human body to the nourishing that plays a part to make moist of Ge Zang Zhou organ of human body, and kidney yang plays a part warm and biochemical to each internal organs organ of human body, be human body at all.Kidney yin, existing its relative property of kidney yang have its interaction again.According to the spirit of the traditional Chinese medical science " treating different diseases with the same therapeutic principle ", all can take method of treatment based on the kidney invigorating.
And the concrete application of the kidney invigorating therapy also should coach according to the theory of the dialectical diagnosis and treatment of Chinese medicine.In general, the syndrome of suffering from a deficiency of the kidney is mainly divided insufficiency of kidney-YANG and deficiency of the kidney yin two big classes.Yang deficiency has the deficiency of vital energy concurrently more, the deficiency of YIN damage of essence of holding concurrently more, and the character that treatment must difference adopts corresponding method of treatment and method.
Technical scheme of the present invention is based on motherland's medical science to deficiency of the liver and kindey, deficiency of qi and blood, the pathogenetic understanding of heat in blood wind-dryness and Therapeutic Principle, with reference to the modern pharmacological research achievement, according to the theory of Chinese medical science prescription.
Summary of the invention
The present invention seeks to be achieved through the following technical solutions
Medicine of the present invention is made by following weight:
Radix Rehmanniae Preparata 104-312g Radix Polygoni Multiflori (system) 104-312g Radix Rehmanniae 104-312g
Fructus Corni 42-125g Herba Ecliptae 52-156g Rhizoma Dioscoreae 35-104g
Cacumen Platycladi 70-209g Radix Ginseng 14-42g Radix Codonopsis 28-84g
Poria 28-84g Cortex Moutan 25-74g Rhizoma Alismatis 21-63g
Rhizoma Anemarrhenae 31-93g Cortex Lycii 21-63g Radix Stellariae 18-53g
Medicine optimum weight proportioning of the present invention is:
Radix Rehmanniae Preparata 208g Radix Polygoni Multiflori (system) 208g Radix Rehmanniae 208g
Fructus Corni 83g Herba Ecliptae 104g Rhizoma Dioscoreae 69g
Cacumen Platycladi 139g Radix Ginseng 28g Radix Codonopsis 56g
Poria 56g Cortex Moutan 49g Rhizoma Alismatis 42g
Rhizoma Anemarrhenae 62g Cortex Lycii 42g Radix Stellariae 35g
Above crude drug can be made tablet, capsule, pill etc. as required.These dosage forms are all refining through the extraction in early stage, and this process is as follows:
Radix Polygoni Multiflori Preparata, Radix Ginseng pulverize separately become fine powder, sieve; Rhizoma Dioscoreae, Cacumen Platycladi, Poria, Cortex Moutan, each 1/3 amount of Cortex Lycii are ground into fine powder, sieve; Surplus and Herba Ecliptae, Radix Codonopsis, Rhizoma Alismatis, Radix Stellariae, the Rhizoma Anemarrhenae, Fructus Corni etc. ten decoct with water 2-3 time simply, soak 30 minutes for the first time, decoct 0.5-3 hour, second and third time, each decocted 0.5-3 hour, and collecting decoction filters, it is 1.35-1.45 (50-60 ℃) that filtrate is concentrated into relative density, add Rhizoma Dioscoreae, Poria and Radix Polygoni Multiflori Preparata powder 177g, mixing, drying, be ground into fine powder, sieve; Radix Rehmanniae Preparata, Radix Rehmanniae decocts with water 2-3 time, soaks 30 minutes for the first time, decocts 0.5-3 hour, second, three times, each decocted 0.5-3 hour, and collecting decoction filters, it is 1.2 (30-40 ℃) that filtrate is concentrated into relative density, stir when being chilled to 40 ℃ and slowly add ethanol down and make and contain the alcohol amount and reach 50-90%, left standstill the leaching supernatant 24 hours, reclaim ethanol, with supernatant concentration to relative density is 1.35-1.45 (50-60 ℃), adds residue Radix Polygoni Multiflori Preparata powder, mixing, dry, be ground into fine powder, sieve, with above-mentioned each medicated powder mixing, add suitable adjuvant, make required dosage form.
Technology after preferred is:
Radix Polygoni Multiflori Preparata, Radix Ginseng pulverize separately become fine powder, sieve; Rhizoma Dioscoreae, Cacumen Platycladi, Poria, Cortex Moutan, each 1/3 amount of Cortex Lycii are ground into fine powder, sieve; Surplus and Herba Ecliptae, Radix Codonopsis, Rhizoma Alismatis, Radix Stellariae, the Rhizoma Anemarrhenae, Fructus Corni etc. ten decoct with water 3 times simply, add 8 times of amounts of water for the first time, soak 30 minutes, decocted 1.5 hours, second and third time respectively adds 6 times of amounts of water, decocts 1 hour, collecting decoction, filter, it is 1.35-1.45 (50-60 ℃) that filtrate is concentrated into relative density, adds Rhizoma Dioscoreae, Poria and Radix Polygoni Multiflori Preparata powder 177g, mixing, 60-80 ℃ of drying is ground into fine powder, sieves; Radix Rehmanniae Preparata, Radix Rehmanniae decocts with water 3 times, adds 8 times of amounts of water for the first time, soaks 30 minutes, decocted second 1.5 hours, respectively add 6 times of amounts of water for three times, decocted 1 hour, collecting decoction filters, and it is 1.2 (30-40 ℃) that filtrate is concentrated into relative density, stir when being chilled to 40 ℃ and slowly add ethanol down and make and contain the alcohol amount and reach 80%, left standstill 24 hours, the leaching supernatant reclaims ethanol, with supernatant concentration to relative density is 1.35-1.45 (50-60 ℃), add residue Radix Polygoni Multiflori Preparata powder, mixing, 60-80 ℃ of drying, be ground into fine powder, sieve,, incapsulate with above-mentioned each medicated powder mixing, make 1000, promptly.
This product can be used for treating the syndrome that deficiency of the liver and kindey, deficiency of qi and blood, heat in blood wind-dryness cause, for determining drug effect, this product has been carried out pharmacodynamics test research, and used capsule is optimal proportion and optimised process preparation and get according to the present invention in the test.Concrete test is as follows:
The specific embodiment:
1 prescription and preparation
1.1 prescription Radix Rehmanniae Preparata 208g, Radix Polygoni Multiflori (system) 208g, Radix Rehmanniae 208g, Fructus Corni 83g, Herba Ecliptae 104g, Rhizoma Dioscoreae 69g, Cacumen Platycladi 139g, Radix Ginseng 28g, Radix Codonopsis 56g, Poria 56g, Cortex Moutan 49g, Rhizoma Alismatis 42g, Rhizoma Anemarrhenae 62g, Cortex Lycii 42g, Radix Stellariae, 35g.
1.2 preparation technology's Radix Polygoni Multiflori Preparata, Radix Ginseng pulverize separately become fine powder, sieve; Rhizoma Dioscoreae, Cacumen Platycladi, Poria, Cortex Moutan, each 1/3 amount of Cortex Lycii are ground into fine powder, sieve; Surplus and Herba Ecliptae, Radix Codonopsis, Rhizoma Alismatis, Radix Stellariae, the Rhizoma Anemarrhenae, Fructus Corni etc. ten decoct with water 3 times simply, add 8 times of amounts of water for the first time, soak 30 minutes, decocted 1.5 hours, second and third time respectively adds 6 times of amounts of water, decocts 1 hour, collecting decoction, filter, it is 1.35-1.45 (50-60 ℃) that filtrate is concentrated into relative density, adds Rhizoma Dioscoreae, Poria and Radix Polygoni Multiflori Preparata powder 177g, mixing, 60-80 ℃ of drying is ground into fine powder, sieves; Radix Rehmanniae Preparata, Radix Rehmanniae decocts with water 3 times, adds 8 times of amounts of water for the first time, soaks 30 minutes, decocted second 1.5 hours, respectively add 6 times of amounts of water for three times, decocted 1 hour, collecting decoction filters, and it is 1.2 (30-40 ℃) that filtrate is concentrated into relative density, stir when being chilled to 40 ℃ and slowly add ethanol down and make and contain the alcohol amount and reach 80%, left standstill the leaching supernatant 24 hours, reclaim ethanol, with supernatant concentration to relative density is 1.35-1.45 (50-60 ℃), adds residue Radix Polygoni Multiflori Preparata powder, mixing, 60-80 ℃ of drying, be ground into fine powder, sieve, with above-mentioned each medicated powder mixing, incapsulate, make 1000, that is, and every dress 0.5g.
2 clinical observation on the therapeutic effect
2.1 whole case 320 examples of clinical data, male's 289 examples, women's 31 examples; At minimum 19 years old of age, maximum 63 years old, average 36 years old, the course of disease was the longest 17 years, and was the shortest 6 months.Wherein 200 examples are organized in treatment, alopecia totalis person 3 examples, alopecia areata person's 31 examples, seborrheic alopecia 166 examples.Matched group 120 examples, alopecia totalis person 1 example, alopecia areata person's 18 examples, seborrheic alopecia 101 examples.
2.2 200 examples are organized in the Therapeutic Method treatment, obey flourish capsule for hair, each 3-5 grain, and clothes were 3 times on 1st.Obeying 1 month is a course of treatment, and general patient takes 2~3 courses of treatment.Matched group 120 examples, clothes gastrodia tuber and fleece-flower root sheet (the changde, hunan pharmaceutical factory of traditional Chinese medicine) each 6 obeyed 3 every day, and obeying 1 month was 1 course of treatment.General patient takes 2~3 courses of treatment.Each is organized and evaluates curative effect after the patient takes 3 courses of treatment.
2.3 efficacy analysis
2.3.1 criterion of therapeutical effect: recovery from illness, produce effects, effective, invalid 4.
Recovery from illness: all grow new long hair, its distribution density, the hair thickness, all same normal hair of color and luster, draw send out test<-; Produce effects: stop alopecia, the alopecia director goes out 2/3 above New Development, the hair thickness, the black and white inequality, draw send out test<-; Effectively: grow 1/3 above New Development, the hair jewelry, expensive clothing and other valuables, color is white, draw send out test<±; Invalid: treatment back does not have and takes a turn for the better, and being has small part fine hair on birds or animals staple length to go out, but comes off very soon, draw send out test<+.
2.3.2 therapeutic outcome: after 3 courses of treatment of taking medicine, by above standard determination, treatment group, 112 examples of fully recovering account for 56%, and produce effects 56 examples account for 28%, and effective 24 examples account for 12%, and invalid 8 examples account for 4%, total effective rate 96%.Matched group, 48 examples of fully recovering account for 40%, and produce effects 19 examples account for 15.8%, and effective 33 examples account for 27.5%, and invalid 20 examples account for 16.7%.Relatively treatment group of 83.3%, two group of statistics of effective percentage significantly is better than matched group (x 2=15.07, P<0.05).
Seborrheic alopecia, alopecia areata is a kind of dermatosis that mainly betides male adults, also is found in the part women.The reason that causes primary disease is more, and conclusion is got up, the blood hot air wind producing, and blood stasis hair key, QI and blood deficiency, deficiency of the liver and kindey is the four big causes of disease of alopecia.In view of the above, intend flourish capsule for hair certainly and treat, Radix Rehmanniae Preparata in the side, the Radix Polygoni Multiflori is enriched blood, YIN nourishing, beneficial marrow, hair growth promoting, hair color; The Radix Rehmanniae, Cortex Moutan heat clearing away, removing heat from blood, yin nourishing.All medicines share, and play altogether and nourish blood, and invigorate blood circulation, and dispel the wind, antipruritic trichogenous effect.Clinical observation, curative effect is preferable, and prolonged application has no side effect.
Below further specify technical scheme of the present invention with the specific embodiment, but the claimed scope of the application is not limited in dosage form described in the embodiment.
The specific embodiment:
Embodiment 1
[prescription] Radix Rehmanniae Preparata 208g Radix Polygoni Multiflori (system) 208g Radix Rehmanniae 208g
Fructus Corni 83g Herba Ecliptae 104g Rhizoma Dioscoreae 69g
Cacumen Platycladi 139g Radix Ginseng 28g Radix Codonopsis 56g
Poria 56g Cortex Moutan 49g Rhizoma Alismatis 42g
Rhizoma Anemarrhenae 62g Cortex Lycii 42g Radix Stellariae 35g
[method for making] Radix Polygoni Multiflori Preparata, Radix Ginseng pulverize separately become fine powder, sieve; Rhizoma Dioscoreae, Cacumen Platycladi, Poria, Cortex Moutan, each 1/3 amount of Cortex Lycii are ground into fine powder, sieve; Surplus and Herba Ecliptae, Radix Codonopsis, Rhizoma Alismatis, Radix Stellariae, the Rhizoma Anemarrhenae, Fructus Corni etc. ten decoct with water 3 times simply, add 8 times of amounts of water for the first time, soak 30 minutes, decocted 1.5 hours, second and third time respectively adds 6 times of amounts of water, decocts 1 hour, collecting decoction, filter, it is 1.35-1.45 (50-60 ℃) that filtrate is concentrated into relative density, adds Rhizoma Dioscoreae, Poria and Radix Polygoni Multiflori Preparata powder 177g, mixing, 60-80 ℃ of drying is ground into fine powder, sieves; Radix Rehmanniae Preparata, Radix Rehmanniae decocts with water 3 times, adds 8 times of amounts of water for the first time, soaks 30 minutes, decocted second 1.5 hours, respectively add 6 times of amounts of water for three times, decocted 1 hour, collecting decoction filters, and it is 1.2 (30-40 ℃) that filtrate is concentrated into relative density, stir when being chilled to 40 ℃ and slowly add ethanol down and make and contain the alcohol amount and reach 80%, left standstill 24 hours, the leaching supernatant reclaims ethanol, with supernatant concentration to relative density is 1.35-1.45 (50-60 ℃), add residue Radix Polygoni Multiflori Preparata powder, mixing, 60-80 ℃ of drying, be ground into fine powder, sieve,, incapsulate with above-mentioned each medicated powder mixing, make 1000, promptly.
Embodiment 2
[prescription] Radix Rehmanniae Preparata 208g Radix Polygoni Multiflori (system) 208g Radix Rehmanniae 208g
Fructus Corni 83g Herba Ecliptae 104g Rhizoma Dioscoreae 69g
Cacumen Platycladi 139g Radix Ginseng 28g Radix Codonopsis 56g
Poria 56g Cortex Moutan 49g Rhizoma Alismatis 42g
Rhizoma Anemarrhenae 62g Cortex Lycii 42g Radix Stellariae 35g
[method for making] Radix Polygoni Multiflori Preparata, Radix Ginseng pulverize separately become fine powder, sieve; Rhizoma Dioscoreae, Cacumen Platycladi, Poria, Cortex Moutan, each 1/3 amount of Cortex Lycii are ground into fine powder, sieve; Surplus and Herba Ecliptae, Radix Codonopsis, Rhizoma Alismatis, Radix Stellariae, the Rhizoma Anemarrhenae, Fructus Corni etc. ten decoct with water 3 times simply, add 8 times of amounts of water for the first time, soak 30 minutes, decocted 1.5 hours, second and third time respectively adds 6 times of amounts of water, decocts 1 hour, collecting decoction, filter, it is 1.35-1.45 (50-60 ℃) that filtrate is concentrated into relative density, adds Rhizoma Dioscoreae, Poria and Radix Polygoni Multiflori Preparata powder 177g, mixing, 60-80 ℃ of drying is ground into fine powder, sieves; Radix Rehmanniae Preparata, Radix Rehmanniae decocts with water 3 times, adds 8 times of amounts of water for the first time, soaks 30 minutes, decocted second 1.5 hours, respectively add 6 times of amounts of water for three times, decocted 1 hour, collecting decoction filters, and it is 1.2 (30-40 ℃) that filtrate is concentrated into relative density, stir when being chilled to 40 ℃ and slowly add ethanol down and make and contain the alcohol amount and reach 80%, left standstill the leaching supernatant 24 hours, reclaim ethanol, with supernatant concentration to relative density is 1.35-1.45 (50-60 ℃), adds residue Radix Polygoni Multiflori Preparata powder, mixing, 60-80 ℃ of drying, be ground into fine powder, sieve, with above-mentioned each medicated powder mixing, granulate, tabletting is made 1000, promptly.
Embodiment 3
[prescription] Radix Rehmanniae Preparata 208g Radix Polygoni Multiflori (system) 208g Radix Rehmanniae 208g
Fructus Corni 83g Herba Ecliptae 104g Rhizoma Dioscoreae 69g
Cacumen Platycladi 139g Radix Ginseng 28g Radix Codonopsis 56g
Poria 56g Cortex Moutan 49g Rhizoma Alismatis 42g
Rhizoma Anemarrhenae 62g Cortex Lycii 42g Radix Stellariae 35g
[method for making] Radix Polygoni Multiflori Preparata, Radix Ginseng pulverize separately become fine powder, sieve; Rhizoma Dioscoreae, Cacumen Platycladi, Poria, Cortex Moutan, each 1/3 amount of Cortex Lycii are ground into fine powder, sieve; Surplus and Herba Ecliptae, Radix Codonopsis, Rhizoma Alismatis, Radix Stellariae, the Rhizoma Anemarrhenae, Fructus Corni etc. ten decoct with water 3 times simply, add 8 times of amounts of water for the first time, soak 30 minutes, decocted 1.5 hours, second and third time respectively adds 6 times of amounts of water, decocts 1 hour, collecting decoction, filter, it is 1.35-1.45 (50-60 ℃) that filtrate is concentrated into relative density, adds Rhizoma Dioscoreae, Poria and Radix Polygoni Multiflori Preparata powder 177g, mixing, 60-80 ℃ of drying is ground into fine powder, sieves; Radix Rehmanniae Preparata, Radix Rehmanniae decocts with water 3 times, adds 8 times of amounts of water for the first time, soaks 30 minutes, decocted second 1.5 hours, respectively add 6 times of amounts of water for three times, decocted 1 hour, collecting decoction filters, and it is 1.2 (30-40 ℃) that filtrate is concentrated into relative density, stir when being chilled to 40 ℃ and slowly add ethanol down and make and contain the alcohol amount and reach 80%, left standstill 24 hours, the leaching supernatant reclaims ethanol, with supernatant concentration to relative density is 1.35-1.45 (50-60 ℃), add residue Radix Polygoni Multiflori Preparata powder, mixing, 60-80 ℃ of drying, be ground into fine powder, sieve, with above-mentioned each medicated powder mixing, pill, make 1000, promptly.

Claims (6)

1, a kind of Chinese medicine composition is characterized in that this Chinese medicine composition is to be made by following raw medicaments in portion by weight:
Radix Rehmanniae Preparata 104-312 weight portion Radix Polygoni Multiflori (system) 104-312 weight portion Radix Rehmanniae 104-312 weight portion
Fructus Corni 42-125 weight portion Herba Ecliptae 52-156 weight portion Rhizoma Dioscoreae 35-104 weight portion
Cacumen Platycladi 70-209 weight portion Radix Ginseng 14-42 weight portion Radix Codonopsis 28-84 weight portion
Poria 28-84 weight portion Cortex Moutan 25-74 weight portion Rhizoma Alismatis 21-63 weight portion
Rhizoma Anemarrhenae 31-93 weight portion Cortex Lycii 21-63 weight portion Radix Stellariae 18-53 weight portion.
2, Chinese medicine composition according to claim 1 is characterized in that this Chinese medicine composition is to be made by following raw material medicaments:
Radix Rehmanniae Preparata 208 weight portion Radix Polygoni Multiflori (system) 208 weight portion Radix Rehmanniae 208 weight portions
Fructus Corni 83 weight portion Herba Ecliptaes 104 weight portion Rhizoma Dioscoreaes 69 weight portions
Cacumen Platycladi 139 weight portion Radix Ginsengs 28 weight portion Radix Codonopsis 56 weight portions
Poria 56 weight portion Cortex Moutans 49 weight portion Rhizoma Alismatis 42 weight portions
The Rhizoma Anemarrhenae 62 weight portion Cortex Lycii 42 weight portion Radix Stellariaes 35 weight portions.
3, Chinese medicine composition as claimed in claim 1 or 2 is characterized in that making clinical common formulations tablet, capsule, pill etc.
4, the preparation method of Chinese medicine composition as claimed in claim 3, it is characterized in that through following process: Radix Polygoni Multiflori Preparata, Radix Ginseng pulverize separately become fine powder, sieve; Rhizoma Dioscoreae, Cacumen Platycladi, Poria, Cortex Moutan, each 1/3 amount of Cortex Lycii are ground into fine powder, sieve; Surplus and Herba Ecliptae, Radix Codonopsis, Rhizoma Alismatis, Radix Stellariae, the Rhizoma Anemarrhenae, Fructus Corni etc. ten decoct with water 2-3 time simply, soak 30 minutes for the first time, decoct 0.5-3 hour, second and third time, each decocted 0.5-3 hour, and collecting decoction filters, it is 1.35-1.45 (50-60 ℃) that filtrate is concentrated into relative density, add Rhizoma Dioscoreae, Poria and Radix Polygoni Multiflori Preparata powder 177g, mixing, drying, be ground into fine powder, sieve; Radix Rehmanniae Preparata, Radix Rehmanniae decocts with water 2-3 time, soaks 30 minutes for the first time, decocts 0.5-3 hour, second, three times, each decocted 0.5-3 hour, and collecting decoction filters, it is 1.2 (30-40 ℃) that filtrate is concentrated into relative density, stir when being chilled to 40 ℃ and slowly add ethanol down and make and contain the alcohol amount and reach 50-90%, left standstill the leaching supernatant 24 hours, reclaim ethanol, with supernatant concentration to relative density is 1.35-1.45 (50-60 ℃), adds residue Radix Polygoni Multiflori Preparata powder, mixing, dry, be ground into fine powder, sieve, with above-mentioned each medicated powder mixing, add suitable adjuvant, make required dosage form.
5, as the preparation method of Chinese medicine composition as described in the claim 4, it is characterized in that this method is: Radix Polygoni Multiflori Preparata, Radix Ginseng pulverize separately become fine powder, sieve; Rhizoma Dioscoreae, Cacumen Platycladi, Poria, Cortex Moutan, each 1/3 amount of Cortex Lycii are ground into fine powder, sieve; Surplus and Herba Ecliptae, Radix Codonopsis, Rhizoma Alismatis, Radix Stellariae, the Rhizoma Anemarrhenae, Fructus Corni etc. ten decoct with water 3 times simply, add 8 times of amounts of water for the first time, soak 30 minutes, decocted 1.5 hours, second and third time respectively adds 6 times of amounts of water, decocts 1 hour, collecting decoction, filter, it is 1.35-1.45 (50-60 ℃) that filtrate is concentrated into relative density, adds Rhizoma Dioscoreae, Poria and Radix Polygoni Multiflori Preparata powder 177g, mixing, 60-80 ℃ of drying is ground into fine powder, sieves; Radix Rehmanniae Preparata, Radix Rehmanniae decocts with water 3 times, adds 8 times of amounts of water for the first time, soaks 30 minutes, decocted second 1.5 hours, respectively add 6 times of amounts of water for three times, decocted 1 hour, collecting decoction filters, and it is 1.2 (30-40 ℃) that filtrate is concentrated into relative density, stir when being chilled to 40 ℃ and slowly add ethanol down and make and contain the alcohol amount and reach 80%, left standstill 24 hours, the leaching supernatant reclaims ethanol, with supernatant concentration to relative density is 1.35-1.45 (50-60 ℃), add residue Radix Polygoni Multiflori Preparata powder, mixing, 60-80 ℃ of drying, be ground into fine powder, sieve,, incapsulate with above-mentioned each medicated powder mixing, make 1000, promptly.
6, Chinese medicine composition is used in preparation is used for the treatment of medicine in dryness seborrheic alopecia and the alopecia areata as claimed in claim 1 or 2.
CN 200510105961 2005-10-08 2005-10-08 A Chinese traditional medicinal composition and its preparation method Pending CN1943704A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103405622A (en) * 2013-08-09 2013-11-27 陕西步长高新制药有限公司 Traditional Chinese medicine composite used for alopecia treatment as well as preparation and detection method thereof
CN103405620A (en) * 2013-08-09 2013-11-27 陕西步长高新制药有限公司 Chinese herbal preparation for treatment of seborrheic alopecia and alopecia areata and preparation method of Chinese herbal preparation
CN103405624A (en) * 2013-08-09 2013-11-27 陕西步长高新制药有限公司 TCM composition for treatment of seborrheic alopecia and alopecia areata and preparation method of TCM composition
CN103405621A (en) * 2013-08-09 2013-11-27 陕西步长高新制药有限公司 TCM composition for treatment of seborrheic alopecia and alopecia areata and preparation method of TCM composition
CN103405623A (en) * 2013-08-09 2013-11-27 陕西步长高新制药有限公司 Traditional Chinese medicine composite used for alopecia treatment as well as preparation and detection method thereof
CN106139094A (en) * 2016-08-17 2016-11-23 马洪星 The Chinese medicine composition for the treatment of seborrheic alopecia

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103405622A (en) * 2013-08-09 2013-11-27 陕西步长高新制药有限公司 Traditional Chinese medicine composite used for alopecia treatment as well as preparation and detection method thereof
CN103405620A (en) * 2013-08-09 2013-11-27 陕西步长高新制药有限公司 Chinese herbal preparation for treatment of seborrheic alopecia and alopecia areata and preparation method of Chinese herbal preparation
CN103405624A (en) * 2013-08-09 2013-11-27 陕西步长高新制药有限公司 TCM composition for treatment of seborrheic alopecia and alopecia areata and preparation method of TCM composition
CN103405621A (en) * 2013-08-09 2013-11-27 陕西步长高新制药有限公司 TCM composition for treatment of seborrheic alopecia and alopecia areata and preparation method of TCM composition
CN103405623A (en) * 2013-08-09 2013-11-27 陕西步长高新制药有限公司 Traditional Chinese medicine composite used for alopecia treatment as well as preparation and detection method thereof
CN103405624B (en) * 2013-08-09 2015-05-20 陕西步长高新制药有限公司 TCM composition for treatment of seborrheic alopecia and alopecia areata and preparation method of TCM composition
CN103405623B (en) * 2013-08-09 2015-07-29 陕西步长高新制药有限公司 A kind of Chinese medicine composition and preparation and determination methods method thereof being used for the treatment of alopecia
CN103405621B (en) * 2013-08-09 2015-09-09 陕西步长高新制药有限公司 A kind ofly treat Chinese medicine composition of seborrheic alopecia and alopecia areata and preparation method thereof
CN103405622B (en) * 2013-08-09 2016-02-10 陕西步长高新制药有限公司 A kind of Chinese medicine composition and preparation and determination methods method thereof being used for the treatment of alopecia
CN106139094A (en) * 2016-08-17 2016-11-23 马洪星 The Chinese medicine composition for the treatment of seborrheic alopecia

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