CN1913874A - Particulate plant sterol compositions - Google Patents
Particulate plant sterol compositions Download PDFInfo
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- CN1913874A CN1913874A CNA2004800414463A CN200480041446A CN1913874A CN 1913874 A CN1913874 A CN 1913874A CN A2004800414463 A CNA2004800414463 A CN A2004800414463A CN 200480041446 A CN200480041446 A CN 200480041446A CN 1913874 A CN1913874 A CN 1913874A
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- plant sterol
- compositions
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Abstract
Particulate plant sterol compositions having defined particle size distribution (psd) characteristics are provided. Processes for preparing the compositions and methods for dispersing the compositions in aqueous media are also provided.
Description
Technical field
The present invention relates to plant sterol, more specifically relate to particulate plant sterol compositions, the Food ﹠ Drink compositions for preparing the method for said composition and contain said composition with designated size distribution (PSD) feature.
Background
Coronary heart disease (CHD) is a kind of common and serious cardiovascular disease, and it can cause many people's death every year in the U.S..Studies show that, plant sterol (plant sterol), comprising plant sterol (phytosterol), phytostanol (phytostanol) and their ester, but hypercholesterolemia reducing and LDL cholesterol and reduce the CHD risk.For example, FDA has ratified being added with that labelling can be used to reduce the CHD risk on the food of plant sterol.Because plant sterol is very hydrophobic chemical compound, they are impregnated in fat-based food such as margarine or the salad dressing usually.In other food applications, with plant sterol and emulsifier to obtain water dispersible, can bring strange taste can significantly reduce the concentration of plant sterol simultaneously usually but contain emulsifying agent.
General introduction
The invention provides particulate plant sterol compositions and manufacture method thereof.Particulate plant sterol compositions of the present invention can be dispersed in the water-bearing media, comprising food containing water and beverage products.In the time of in being dispersed in water-bearing media such as juice, said composition can not brought grit, Chalk or other unwanted attribute of sensation (promptly on color, taste and mouthfeel) to water-bearing media.Also provide and made this method for compositions, can avoid being graded by sized the nonconforming particulate needs of recovery size then thereby this method comprises a Ginding process.
On the one hand, the invention provides and contain one or more plant sterol grains of composition.Said composition demonstrates the particulate multimodal volume weighting of described one or more plant sterols or quality weighting particle size distribution (PSD) and multimodal surface area weighting PSD.Said composition when be dispersed in the test juice in the time described test juice have acceptable mouthfeel.
Multimodal volume weighting or quality weighting PSD can show that the diameter at first peak of plant sterol granule is less than 2 microns, and the volume weighting mean diameter is about the 0.3-0.5 micron; With the diameter at second peak of plant sterol granule be the 2-35 micron, the volume weighting mean diameter is about the 8-12 micron.Second peak can account for about 65%-85% of described volume weighting or quality weighting PSD, and first peak can account for about 15%-35% of described volume weighting or quality weighting PSD.On the other hand, in described volume weighting or quality weighting PSD, diameter greater than 35 microns the particulate percent by volume of all plant sterols less than about 3% or less than about 0.5%.
Here the compositions that provides can demonstrate the particulate multimodal surface area of one or more plant sterols weighting PSD.Surface area weighting PSD shows that the diameter at first peak of plant sterol granule is less than 2 microns; With the diameter at second peak of plant sterol granule be the 2-35 micron, and the surface area weighted average particle diameter at described second peak is about the 8-12 micron.Particulate first peak of plant sterol accounts for about 78%-92% of described surface area weighting PSD.Diameter is about 0.5 micron or littler less than the surface area weighted average particle diameter at first peak of plant sterol granule of 2 microns.Diameter is about 0.3 micron-0.5 micron less than the surface area weighted average particle diameter at first peak of plant sterol granule of 2 microns, or about 0.4 micron.
On the other hand, total specific surface area of the multimodal surface area weighting PSD of compositions is greater than about 2m
2/ g, or be about 2.5-7m
2/ g, or be about 2.8-6.5m
2/ g.
In another embodiment, the invention provides to contain and to be dispersed in the water-bearing media or to be dispersed in plant sterol grains of composition in the water-bearing media.For example, described compositions can be an Aquo-composition.In other example, said composition is a powder composition.Described compositions can be the Foods or drinks compositions.Beverage composition for treating dental erosion can be selected from juice, concentrated juice, coffee, tea, silkscreen suction (smoothie), snow gram (shake), bean milk, Rice ﹠ peanut milk, iced drink, beverage containing milk, replace food and drink material, weight-reducing drinks and nutritional supplementation beverage.Food compositions can be selected from bread, bakery, confection, ice cream, preserve, egg, egg succedaneum, ice cream, yoghourt, healthy complementary goods, replace canteen product and nutriment.
In hydrous material, contain the particulate dispersion composite of one or more plant sterols and do not have or have only slight detectable Chalk mouthfeel.Particulate plant sterol compositions can be mixed with hydrous material or is dispersed in the hydrous material to avoid unwanted attribute of sensation in the plant sterol granule aqueous dispersion basically.Unwanted attribute of sensation can be Chalk, grit, drying or powdery mouthfeel.
On the other hand, the invention provides a kind of method of making particulate plant sterol compositions.This method comprises cooling plant sterol raw material; With impact type or pulverize formula and grind described refrigerative plant sterol raw material.The plant sterol raw material can not contain emulsifying agent.About 88%-100% of plant sterol raw material weight (for example about 88,89,90,91,92,93,94,95,96,97,98,99 or 100%) is one or more plant sterols.The plant sterol raw material can comprise vitamin E and/or tocopherol.The plant sterol raw material can be the about 1mm-4mm of diameter, for example lozenge form of about 2mm.
The plant sterol raw material can be cooled to pact-100 to-275 , or about-175 to-250 , or-225 .The plant sterol raw material can be used cooled with liquid nitrogen.When with cooled with liquid nitrogen, can in noble gas (for example nitrogen), grind the plant sterol raw material.
Impact type or pulverize formula and grind available gap mill and carry out.The rotor-stator gap of gap mill can be about 0.025 " 0.05 ", or about 0.03 ".Impact type or pulverize formula and grind and to carry out once.The average end speed (tip speed) of gap mill can be about 110m/s-150m/s, or about 120-135m/s.The temperature of the particulate plant sterol compositions that draws off from gap mill can be about-25 to-275 , or is about-40 to-75 , or is about-40 to-50 .Impact type or pulverize formula and grind and in noble gas, to carry out.Can be below existing impact type or pulverize formula and grind refrigerative plant sterol raw material during one or more materials: flowable, coloring agent, flavorant, vitamin, mineral, fibrous raw material, protein and nourishing additive agent.
In another embodiment, the invention provides a kind of method of making particulate plant sterol compositions, this method is included in inlet pressure and is about 5-6 crust, outlet temperature less than grinding the plant sterol raw material in the Hametag mill of about 100 .Grinding can be carried out under the temperature of about 60-80 , and can carry out once and/or carry out under noble gas (for example nitrogen).The plant sterol raw material can be as mentioned description.Can be below existing grind the plant sterol raw material during one or more materials: flowable, coloring agent, flavorant, vitamin, mineral, fibrous raw material, protein and nourishing additive agent.
In another embodiment, the invention provides the method for making the particulate plant sterol compositions aqueous dispersion.This method comprises mixes particulate plant sterol compositions with hydrous material, wherein said particulate plant sterol compositions demonstrates above-mentioned multimodal surface area weighting PSD.
Unless otherwise defined, the those of ordinary skill institute common sense of the connotation of all technology used herein and scientific terminology and technical field involved in the present invention is identical.Though, suitable method and material are described below putting into practice or testing and to adopt method and the material similar or identical in the process of the present invention with content described herein.All publications mentioned in this article, patent application, patent and other list of references are all included in as a reference in full.Under conflict situations, this description comprises that definition will control (scope of the invention).In addition, material, method and embodiment only are exemplary, are not intended to restriction.
By following detailed description and claim with obvious other features and advantages of the present invention.
Detailed Description Of The Invention
The invention provides the compositions of the plant sterol that contains one or more particle form with regulation PSD feature.Described particulate plant sterol compositions can be dispersed in the water-bearing media, for example some food or beverage products, and it can not bring grit or Chalk mouthfeel to product.Also describe the method for making particulate plant sterol compositions, comprised once the method for finishing (one-pass).
The plant sterol chemical compound
Here the particulate composition that provides can contain one or more plant sterol chemical compounds.Term " plant sterol " includes but not limited to plant sterol, plant sterol ester, phytostanol and phytostanol ester.Plant sterol (and plant sterol ester) is present in the material that exists in the diet as the microcomponent of vegetable oil is natural usually, and phytostanol (and phytostanol ester) is the hydrogenated products of plant sterol.
The plant sterol that is used for here can comprise any of all places isomer and stereoisomeric forms in any ratio, for example α-, β-or γ-isomer.Typical plant sterol chemical compound comprises α-Gu Zaichun, clionasterol, cupreol, campesterol, stigmasterol, brassicasterol, chondrillasterol (spinosterol), taraxasterol, desmosterol, chalinosterol, poriferasterol, chionasterol, ergosterol, Δ-5-avenasterol (avenosterol), Δ-5-campesterol, loyal paulownia sterol, Δ-5-stigmasterol, Δ-7,25-bean steroid dienol (stigmadienol), Δ-7-avenasterol, Δ-7-cupreol and Δ-7-brassicasterol.
The suitable example of plant sterol ester includes but not limited to: the cupreol laurate, the α-Gu Zaichun laurate, the clionasterol laurate, campesterol myristinate (myristearate ester), the stigmasterol oleate, the campesterol stearate, the cupreol oleate, the cupreol cetylate, the cupreol linoleate, the α-Gu Zaichun oleate, the clionasterol oleate, the cupreol myristinate, the cupreol ricinoleate ester, the campesterol laurate, the campesterol ricinoleate ester, the campesterol oleate, the campesterol linoleate, the stigmasterol linoleate, the stigmasterol laurate, the stigmasterol alkyl caproate, the α-Gu Zaichun stearate, the clionasterol stearate, the α-Gu Zaichun myristinate, the clionasterol cetylate, the campesterol ricinoleate ester, the stigmasterol ricinoleate ester, campesterol ricinoleate ester and stigmasterol stearate.
Useful phytostanol chemical compound comprise α-, β-and γ-sitostamol (sitostanol), campestanol (campestanol), stigmastanol, Herba Spinaciae stanol (spinostanol), Herba Taraxaci stanol (taraxastanol), colza stanol (brassicastanol), chain stanol (desmostanol), chalinostanol, porous stanol (poriferastanol), wear shellfish sponge stanol (clionastanol) and ergostanol (ergostanol).
At last, the phytostanol ester that contains in the compositions that here provides includes but not limited to: β-sitostamol laurate, the campestanol myristinate, stigmastanol alcohol oleate, the campestanol stearate, β-sitostamol oleate, β-sitostamol cetylate, β-sitostamol linoleate, β-sitostamol myristinate, β-sitostamol ricinoleate ester, the campestanol laurate, the campestanol ricinoleate ester, the campestanol oleate, the campestanol linoleate, stigmastanol alcohol linoleate, stigmastanol alcohol laurate, stigmastanol alcohol alkyl caproate, stigmastanol alcohol stearate, α-sitostamol laurate, γ-sitostamol laurate, α-sitostamol oleate, γ-sitostamol oleate, α-sitostamol stearate, γ-sitostamol stearate, α-sitostamol myristinate, γ-sitostamol cetylate, the campestanol ricinoleate ester, stigmastanol alcohol ricinoleate ester, the campestanol ricinoleate ester, β-sitostamol, α-sitostamol, γ-sitostamol, campestanol and stigmastanol.
The plant sterol raw material
Particulate plant sterol compositions is normally from the plant sterol feedstock production, for example, and as the description in the following method.The plant sterol raw material can contain above-mentioned one or more plant sterol chemical compounds.For example, the plant sterol raw material can any relative scale (for example, 1: 1,2: 1,3: 1,4: 1,5: 1,6: 1,7: 1,8: 1,9: 1 or 10: 1) contain various plants sterol compound (for example, 2,3,4,5,6,7,8,9,10,11,12,13,14,15,20 or more).
The plant sterol raw material can be from many plant origins, for example, Testa oryzae oil, corn fiber oil, Fructus Maydis oil, Semen Tritici aestivi germ oil, safflower oil, avenol, olive oil, Oleum Gossypii semen, soybean oil, Oleum Arachidis hypogaeae semen, Canola oil, tea, Oleum sesami, Oleum Vitis viniferae, rapeseed oil, Semen Lini oil, tall oil and available from other oils and various other Semen Brassicae Campestris crop of wood pulp.Though plant sterol usually from plant, also can prepare plant sterol by for example synthetic method, so just do not need to obtain from plant origin.In addition, it is the mixture of purified or synthetic each plant sterol chemical compound that the plant sterol raw material can be made into, and perhaps can be the side-product that obtains by purification other products (for example, from plant origin).For example, the plant sterol raw material can be used as the side-product acquisition of making vitamin E and/or tocopherol from vegetable oil deodorizer distillate (deodorizer distillate).
According to the application, the plant sterol raw material can contain or not contain other composition.For example, certain plants sterol raw material can contain vitamin E and/or one or more tocopherols, for example when raw material is the side-product acquisition of conduct manufacturing vitamin E.In some examples, the plant sterol raw material of about 88%-100% (for example, 88,89,90,91,92,93,94,95,96,97,98 or 99%) is made of one or more plant sterol chemical compounds.For example, in one embodiment, the plant sterol raw material is by cupreol, campesterol and the stigmasterol of about 85-90 weight % (for example, about 85,86,87,88,89 or 90 weight %) constitute at the most.In other example, the plant sterol raw material can be made of the mixture of cupreol, campesterol, stigmasterol, brassicasterol, campestanol, β-sitostamol and Δ-5-avenasterol of about 88-100 weight % (for example, about 88,89,90,91,92,93,94,95,96,97,98,99 or 100 weight %) at the most.In some example, the plant sterol raw material can be made of the mixture of cupreol, campesterol, stigmasterol, brassicasterol, campestanol, β-sitostamol and Δ-5-avenasterol of about 89-91 weight %.
In some applications, the plant sterol raw material does not contain emulsifying agent (for example, lecithin, list-and/or two-glyceride, Isosorbide Dinitrate (soribitan ester), sucrose ester).Bound by theory not, we think that adding these becomes branches to bring undesirable attribute of sensation (for example, with regard to color, taste or mouthfeel) to compositions.
In other is used, contain one or more following compositions in the plant sterol raw material: flowable (for example, sodium aluminosilicate, potassium ferrocyanide); Coloring agent (for example, beta-carotene); Vitamin or mineral (for example, vitamin A, C, D, E and K and vitamin B group; With mineral Ca, Fe, Mg, Zn, K and Se); Cellulose (solubility and insoluble fibre; For example, Fructus Hordei Vulgaris beta fibers, Herba bromi japonici beta fibers, mannan, galactomannan, Semen Tritici aestivi, Herba bromi japonici, corn and Fructus Hordei Vulgaris bran); Protein (for example, aminoacid, soybean protein, milk or egg protein); Or nourishing additive agent (for example, bilobalide (gingko biloba), Radix Ginseng, chrondroitin, glycosamine, Echinacea (Echinacea), chromium picolinate (chromium picolinate), folic acid, soybean isoflavone, tangeritin, sabal, sterol glycoside and flavanolignan (flavolignan)).
The plant sterol raw material can be any form, for example lozenge, the rough solid of wax sample or powder.For example, the plant sterol raw material can obtain from impure tocopherol-sterol mixture by crystallization, with this mixture drying, melt and make the lozenge of the about 1-4mm of diameter (for example, 1,2,3 or 4mm).Plant sterol chemical compound and plant sterol raw material are (for example, sterol lozenge) can be available from for example Cargill, Incorporated (Minneapolis, Minn.), Loders andCroklaan (Channahon, Ill.), Cognis Nutrition and Health (La Grange, Ill.), ForbesMeditech (Vancouver, B.C.Canada) and ADM (Decatur, Ill.).In addition, plant sterol chemical compound and raw material also can synthesize and/or obtain (for example, as United States Patent (USP) 6,411,206 from plant origin; 5,502,045; 6,087,353 and 4,897,224 description).
The particle size distribution characteristic of particulate plant sterol compositions
Here the particulate plant sterol compositions that provides can be described by its PSD feature.The PSD feature can be used particle size analyzer, this apparatus measures Mie-scattered light and Fraunhofer-scattered light, for example Horiba LA-910 type Particle Size Analyzer.Particulate plant sterol compositions demonstrates specific volume weighting or quality weighting PSD feature and specific surface area weighting PSD feature usually.Without being limited by theory, we think that the compositions (for example, food, beverage or Aquo-composition) that described PSD feature that this particulate plant sterol compositions demonstrates can not make them be dispersed in wherein has Chalk, grit, powdery, greasy or other unwanted attribute of sensation (promptly with regard to mouthfeel, taste and color).
For example, phytosterol compositions can demonstrate particulate multimodal volume weighting of one or more plant sterols or quality weighting particle size distribution (PSD).Term " multimodal " is meant that in the text PSD has shown the distribution with at least two kinds of different models or peak maximum.In the certain situation, multimodal PSD can be bimodal.
For example, volume weighting or quality weighting PSD can show, the diameter at first peak of plant sterol granule is less than 2 microns, and the volume weighting mean diameter is about 5 microns or littler (for example, about 3-5 micron, or about 0.3,0.35,0.4,0.45 or 0.5 micron).Wait with term " first ", " second ", " the 3rd " in the literary composition and describe the PSD peak and do not represent the outward appearance at these peaks or the time dependence of measurement, also do not represent the size at these peaks.Diameter is called as " narrow " peak here less than the particulate PSD of 2 microns plant sterol peak.First peak among volume weighting or the quality weighting PSD can account for about 15%-35% or any value between this (for example, about 16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33 or 34%) of total volume weighting or quality weighting PSD.Particulate plant sterol compositions can show that the diameter at second peak of plant sterol granule of volume weighting or quality weighting multimodal PSD is the 2-35 micron.The volume weighting mean diameter at second peak can be about the 8-12 micron, or the arbitrary value between this (for example, about 8.5,9,9.5,10,10.5,11 or 11.5 microns).Second peak can account for about 65%-85% or the arbitrary value between this (for example, about 66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83 or 84%) of total volume weighting or quality weighting PSD.In addition, among volume weighting or the quality weighting PSD, diameter accounts for total volume weighting or quality weighting PSD greater than all plant sterol granules of 35 microns percentage by volume is less than about 3%, for example, and less than about 2.5%, 2%, 1.5%, 1% or 0.5%.
Particulate plant sterol compositions described herein also demonstrates multimodal surface area weighting PSD.Multimodal surface area weighting PSD can be bimodal.Surface area weighting PSD can show, the diameter at first peak of plant sterol granule is less than 2 microns, for example, and " narrow " peak.Diameter less than first peak of plant sterol granule of 2 microns (for example, " narrow " peak) surface area weighted average particle diameter can be about the 0.3-0.5 micron, for example, about 0.3,0.35,0.4,0.45 or 0.5 micron.First peak of plant sterol granule can account for about 78%-92% of surface area weighting PSD.Multimodal surface area weighting PSD can show that the diameter at second peak of plant sterol granule is the 2-35 micron, and surface area weighted average particle diameter is about 8-12 micron (for example, about 8.5,9,9.5,10,10.5,11 or 11.5 microns).
Total specific surface area of PSD also can be to estimate the useful parameter of particulate plant sterol compositions.In compositions of the present invention, total specific surface area of multimodal surface area weighting PSD can be greater than about 2m
2/ g, for example, about 2.5-7m
2/ g, or about 2.8-6.5m
2/ g.
Other physical features of particulate plant sterol compositions
Particulate plant sterol compositions can be a various forms, for example solid or liquid.For example, particulate plant sterol compositions can for example present powder type immediately or be used for being dispersed in subsequently water-bearing media after the preparation.Perhaps, particulate plant sterol compositions can be wherein to be dispersed with the particulate Aquo-composition of plant sterol.Aquo-composition can be the Foods or drinks compositions that contains water.For example, particulate plant sterol compositions can be dispersed in the beverage, described beverage such as juice are (for example, Fructus Citri tangerinae, Fructus Vitis viniferae, cranberry, Fructus Mali pumilae, Fructus actinidiae chinensis, Fructus Mangifera Indicae, peach, Fructus Ananadis comosi, Lee, Fructus Pruni pseudocerasi, Fructus Musae, luxuriant Punica granatum L., Fructus Chaenomelis, grapefruit, Fructus Citri grandis (natsudaidai), tangerine, clementine, mandarin orange, black currant, Citrullus vulgaris, Fructus Melo, the rib melon, Fructus Citri Limoniae, Citrus aurantium Linn., pears, blue berry, blackberry, the juice of fruit such as Fructus Rubi or Fructus Fragariae Ananssae, or Fructus Lycopersici esculenti, Radix Dauci Sativae, Herba Apii graveolentis, Fructus Cucumidis sativi, Herba Spinaciae, Caulis et Folium Lactucae sativae, Herba Oenanthes Javanicae, tender shoots, Radix Betae, medical herbs, the juice of Caulis et Folium Brassicae capitatae or wheat straw vegetables such as (wheat grass), or mixed juice), concentrated juice, coffee, tea, silkscreen is inhaled, the snow gram, bean milk, Rice ﹠ peanut milk, iced drink, beverage containing milk (for example, whole milk, 1% milk, 2% milk, heavy butter, half and half butter (half and half), whipped cream or light butter (light cream)), for the food and drink material, weight-reducing drinks or nutritional supplementation beverage.Particulate plant sterol compositions can be impregnated in food compositions, for example, powder (for example, light flour, wheat flour, rye meal, Semen sojae atricolor powder or rice flour), bakery (for example, bread, doughnut, bagel, muffin, scone), confection, ice cream, preserve, egg liquid, liquid egg replacer product, ice cream, yoghourt, healthy complementary goods, for canteen product or nutriment.In some solid food compositions, particulate plant sterol compositions can at first be dispersed in liquid such as the Aquo-composition, then it is mixed solid food compositions (for example, bread).Perhaps, phytosterol compositions can mix with other solid and/or powdered food product compositions (for example, powder).
Make the method for particulate plant sterol compositions
Above-mentioned particulate plant sterol compositions can and/or pulverize the formula grinding technique or jet grinding or eddy milling technology are made with impact type.Described technology can be carried out once, does not promptly need the material after grinding is carried out size fractionation and reclaims the material regrinding that does not conform to size requirements.
In one approach, earlier with the cooling of above-mentioned plant sterol raw material and then impact type or pulverize formula and grind.For example, the plant sterol raw material can be cooled to pact-100 to-275 , or about-175 to-250 .In certain embodiments, the plant sterol raw material is cooled to-225 approximately.The plant sterol raw material can be used cooled with liquid nitrogen, therefore will grind in noble gas (nitrogen).We think, by pre-cooled plant sterol raw material plant sterol are become fragile and be easy to grind.As indicated above, can be when having one or more following materials impact type or pulverize formula and grind pre-cooled plant sterol raw material: flowable, coloring agent, flavorant, vitamin, mineral, fibrous raw material, protein or nourishing additive agent.Can be in noble gas such as nitrogen impact type or pulverize formula and grind pre-cooled plant sterol raw material.
Impact type or pulverize formula and grind available gap mill and carry out.Gap mill generally includes a plurality of stators that center on the flat blade of bell-shaped rotor arrangement and conical rib is arranged accordingly.Particle size reduction is partly realized by usefulness rotor and stator peening particle, but mainly is by granule-granule collision.Gap between rotor-stator is about 0.025 " 0.05 " usually.For example, in certain embodiments, the gap between rotor-stator is about 0.03 ".Rotor speed is adjustable, so that on average hold speed to be about 110m/s-150m/s.In certain embodiments, on average hold speed to be about 120-135m/s.Gap mill can be available from MicrotecMicrotec (for example, Microtec-Microtec gap mill), Bauermeister (for example, Bauermeister ASIMA grinder), Netzsch and Hosokawa-Bepex.
Impact type and/or pulverize the formula grinding technique and do not need product is passed through classifying screen.In certain embodiments, the impact type of for example carrying out with gap mill or pulverize formula and grind and only carry out once.Reducing granularity afterwards can be from for example drawing off particulate plant sterol compositions the gap mill, and its temperature is about-25 to-275 (for example, temperature is about-40 to-75 , or temperature is about-40 to-50 ).In some embodiments, the temperature of the compositions that draws off is about-75 .
In other method of making particulate plant sterol compositions, the plant sterol raw material grinds in injecting type or spiral vortex type grinding machine.In these grinding machines, the driving force of pulverizing is from the high volume flow of gases at high pressure or other gas, nitrogen for example, so it will be to grind to produce inert environments.Grind mainly by granule-granule collision, the heat that produces in this process absorbs by the gas cooled of gas when for example the 5-6 crust expand into atmospheric pressure, and by high gas flow it is taken away.According to the design of grinding chamber and vortex, the granule that produces during the fine grinding raw material-granule active force just can occur when reaching minimum particle size.Hametag mill can be available from SuperFine Ltd., INOX Ltd. and Netzsch, perhaps can be as United States Patent (USP) 5,855, and 326 description.
In the method, the inlet pressure of spiral vortex type or injector-type mill is about the 5-6 crust.Grinding can be carried out in room temperature, for example about 60-80 .The outlet temperature of spiral vortex type or injector-type mill is less than about 100 .As indicated above, available spiral vortex type or injector-type mill grind once, and be as indicated above, can carry out when having one or more following materials: flowable, coloring agent, flavorant, vitamin, mineral, fibrous raw material, protein or nourishing additive agent.Spiral vortex type or injecting type grind and can carry out in noble gas.
Because without being limited by theory, we think, compare other and adopt the plant sterol raw material of fusing and/or make raw material contact temperature be about the method for the air of 300-400 , impact type described here/pulverize formula or the spiral vortex type Ginding process is less to the oxidative degradation damage of plant sterol in the plant sterol raw material.
The present invention also provides the method for making the aqueous dispersion of particulate plant sterol compositions.In the method, particulate plant sterol compositions is mixed with hydrous material.Particulate plant sterol compositions demonstrates the multimodal volume/mass weighted sum surface area weighting PSD of afore mentioned rules.In the certain situation, but short time (for example, 1 second to 1 minute) mild heat (for example, 90-212 ) dispersion or it is carried out homogenizing.See for example U.S. Patent Publication No.2003/0232118A1.
In another embodiment, the invention provides the method for the dispersion of making particulate plant sterol compositions.In the method, with particulate plant sterol compositions with the pulp homogenizing.Pulp can be the pulp of any kind, comprising but be not limited to fruits and vegetables slurry, as mandarin orange pulp (for example, Fructus Citri tangerinae, Citrus aurantium Linn., Fructus Citri Limoniae and grapefruit pulp); The Fructus Mali pumilae pulp; The pear pulp; The Fructus Pruni salicinae pulp; The Fructus Persicae pulp; The Fructus Pruni pseudocerasi pulp; The Fructus Mangifera Indicae pulp; Luxuriant Punica granatum L. pulp; The Fructus Chaenomelis pulp; With the mixing berry syrup.Pulp can contain the 2-8% pectin of having an appointment, or arbitrary value therebetween (for example, about 2,3,4,5,6,7 or 8%).In the certain situation, can use the pulp that contains 5% pectin of having an appointment.Can add water in the homogenizing process to help the liquefaction pulp.If make water, then the ratio of water and pulp can be about 1: 1-4: 1, or the arbitrary value between this (for example, about 1.5: 1,2: 1,2.5: 1,3: 1 or 3.5: 1).In the certain situation, the ratio of water and pulp is 3: 1.Before the homogenizing; the plant sterol granule can account for about 1%-10% of water/pulp/plant sterol granulate mixture gross weight; or the arbitrary value between this (for example, about 1.2,1.5,1.8,2,2.2,2.5,2.8,3,3.2,3.5,3.8,4,4.2,4.5,4.8,5,5.2,5.5,5.8,6,6.2., 6.5,6.8,7,7.2,7.5,7.8,8,8.2,8.5,8.8,9,9.2,9.5 or 9.8 weight %).In the certain situation, particulate plant sterol compositions can account for about 2-3 weight %.
In this method, pulp, water and particulate plant sterol compositions can be mixed before the homogenizing.For example, available benchtop blender utilize high shear force (for example about 10,000rpm) pulp, water and particulate plant sterol compositions are pre-mixed.Premixing can be carried out for example about 1-10 minute or about 5 minutes, was well dispersed in pulp/aqueous mixtures up to particulate plant sterol compositions.Pulp/water/plant sterol granulate mixture then can be by homogenizing.Pulp/water/plant sterol granulate mixture can divide a stage or a plurality of stage to carry out homogenizing.For example, pulp/water/plant sterol granulate mixture can be in two stages homogenizing.In the certain situation, pulp/water/plant sterol granulate mixture is at phase I homogenizing under about 3000-5000 pound/square inch (psi), then at second stage homogenizing under about 300-800psi.Under the certain situation, pulp/water/plant sterol granulate mixture is at phase I homogenizing under 4500psi, at second stage homogenizing under 500psi.Also but homogenizing repeatedly.Through the pure pulp of per 10 grams of the pulp/water/plant sterol granulate mixture of homogenizing (for example; the water that does not comprise adding; weight in wet base) contains have an appointment 0.5-1.5 gram or this arbitrary value (for example, about 0.6,0.7,0.8,0.9,1.0,1.1,1.2,1.3 or 1.4 grams) plant sterol granule wherein.
After the homogenizing, the pulp/water/particulate plant sterol compositions mixture of process homogenizing can be added into the Foods or drinks compositions, as mentioned above.In other cases, the pulp/water/plant sterol granulate mixture of process homogenizing can be added into water-bearing media (as mentioned above), and mixes to obtain the particulate aqueous dispersion of plant sterol.In the certain situation, water-bearing media can be a juice, as the juice of single concentration, as Fructus Citri tangerinae fruit juice or cranberry fruit juice.Under other situation, water-bearing media can comprise pulp/water/plant sterol granulate mixture and the fruit or the vegetable condensed juice of water, process homogenizing.Every part of (normally 6-12 ounce) aqueous dispersion can contain the 0.3g-1.8g that has an appointment (or between arbitrary value, for example about 0.4,0.5,0.6,0.7,0.8,0.9,1.0,1.1,1.2,1.3,1.4,1.5,1.6 or 1.7) the plant sterol granule.
Without being limited by theory, we think and consequently make the particulate plant sterol compositions of homogenizing have good dispersibility, viscosity and stability by effectively homogenizing particulate plant sterol compositions of some components of pulp or pulp such as pectin or terpenoid.In addition, when mixing water-bearing media, resulting composition has good mouthfeel and sensory features and (for example, does not have Chalk, greasy, grit or puckery sensation; And there is not or has only slight haloing (ringing), separate or occur white particle (" floating thing ")).
Embodiment
Embodiment 1-makes the plant sterol granule (SP-1) of spraying granulation
Sterol lozenge (Cargill with 2 millimeters of 5 kilograms of diameters, Incorporated, 90 weight % are the mixture of cupreol, campesterol, stigmasterol, brassicasterol, campestanol, β-sitostamol and Δ-5-avenasterol) in the Parr reactor, melt, and the speed with 2.7gph pushes SprayingSystems under the nitrogen pressure of 35psig, two fluid tips of Inc.SU-42, afterwards, with 90 pounds of/square inch (gauge pressure) air (psig) with 3.6 scfm (scfm) atomizing fluids; Fluid temperature (F.T.) is 375 .It is indoor that product is collected in the non-pressurized taper of room temperature.Carrying out grain size analysis [seeing Table I] with Horiba LA-910 Particle Size Analyzer shows, sterols accounts for the 6 volume % (determining on the volume weighting PSD) and the 56 surface area % (definite on surface area weighting PSD) in " narrow " zone (diameter less than 2 microns granule), and the average diameter at " narrow " peak is 0.6 micron or bigger.The specific area of all substances that calculate is 1.1m
2/ g.
The product of embodiment 1 is mixed orange juice (seeing embodiment 9) with the level of 4.25g/L.Feeling evaluation to fruit juice confirms that it has unacceptable " powdery/Chalk " mouthfeel, causes dry sensation in mouth.
Embodiment 2-makes the low plant sterol granule (CG-79) that grinds (Cryo-Milled) that mixes
The sterol lozenge (as mentioned above) that online cooling diameter is 2 millimeters, " inlet temperature before the Microtec 200 type gap mills in gap is about-175 to make it have 0.030 entering.With the charging rate and 12 of about 465#/hr, the refrigerative in advance sterol lozenge grinding of the rotor speed of 000rpm general-inferior.The temperature of charge that comes out from grinder is-45 to-50 .Product is analyzed on Horiba LA-910 Particle Size Analyzer.See Table I.
In the test of the orange juice shown in embodiment 1 and 9, estimate CG-79.This product is be evaluated as unacceptable.
Embodiment 3-makes the plant sterol granule (CG-56) of cryogrinding
The sterol lozenge (as mentioned above) that online cooling diameter is 2 millimeters, " inlet temperature before the Microtec 200 type gap mills in gap is about-245 to make it have 0.030 entering.With the charging rate and 12 of about 630#/hr, the rotor speed of 000rpm is ground refrigerative in advance sterol lozenge once.The temperature of charge that comes out from grinder is-75 .Product is analyzed (seeing embodiment 8) on Horiba LA-910 Particle Size Analyzer.See Table I.
Embodiment 4-makes the plant sterol granule (CG-522) of cryogrinding
The sterol lozenge (as mentioned above) that online cooling diameter is 2 millimeters, " inlet temperature before the Microtec 200 type gap mills in gap is about-225 to make it have 0.030 entering.With the charging rate and 12 of about 500-550#/hr, the rotor speed of 000rpm is ground refrigerative in advance sterol lozenge once.Single grinds and carries out about 3.5 hours (1700# sterol lozenge) altogether.Product is analyzed on Horiba LA-910 Particle Size Analyzer.The temperature of charge that comes out from grinder is-75 .See Table I.
Embodiment 5-makes the plant sterol granule (SF-1) of eddy milling
The sterol lozenge (as mentioned above) that makes 2 millimeters of diameters enters 6 with the speed of about 4kg/hr, and " D SuperFine, the Ltd. Hametag mill does not cool off raw material before.The driving force of this grinding machine is the air intake air-flow that pressure is about 5.5 crust.Product is analyzed on Horiba LA-910 Particle Size Analyzer.See Table I.
The product of embodiment 5 is mixed orange juice, as described in embodiment 1 and 9.Fabulous to this product evaluation in test fruit juice, there are not detectable " powdery/Chalk " mouthfeel or xerostomia effect.
The particulate feature of plant sterol of embodiment 6-spraying granulation, cryogrinding and eddy milling
Analytic sample SP-1, CG-79, CG-56, CG-522 and SF-1 on Horiba LA-910 Particle Size Analyzer, and with the particulate distribution of mapping analysis of every kind of small product size (or quality) weighting PSD and particle diameter or surface area weighting PSD and particle diameter.Also calculated total specific surface area of every kind of compositions according to particle size distribution.The results are shown in following Table I.
Table I
| SP-1 | CG-79 | CG-56 | CG-522 | SF-1 | |
| " narrow " peak only, volume weighting PSD-accounts for overall % | 6 | 13.1 | 18.3 | 19 | 30 |
| " narrow " peak only, surface area weighting PSD-accounts for overall % | 56 | 75 | 79 | 83 | 85 |
| " narrow " peak only, surface area weighting PSD-average diameter [μ] | 0.6 | 0.6 | 0.5 | 0.4 | 0.4 |
| Total specific surface area distribution-calculate [m by PSD 2/g] | 1.1 | 2.0 | 2.9 | 4.4 | 6.1 |
| The percentage ratio of the material of volume weighting PSD-diameter＞35 μ | 3.7 | 9.4 | 0 | 0.3 | 0 |
Embodiment 7-is to the particulate feeling evaluation of plant sterol in the orange juice
The judge group of 9 sensation judge compositions has estimated mouthfeel, taste and the color/outward appearance of the numbered samples of the orange juice (seeing embodiment 9) that contains 1g/8oz (240mL) SP-1, CG-56 and SF-1 particulate plant sterol compositions in round-table discussion under unwitting situation.Not to any specialized training that the member carried out this evaluation in the judge group.Allow and pass judgment on the sensory features that the group member describes every kind of sample, focus on mouthfeel.Think that the Chalk of SF-1 feels minimum, say it is the most acceptable from mouthfeel.The results are summarized in Table II.
Table II
| Sample | Color/outward appearance | Taste | Mouthfeel | Acceptable degree |
| 1. untreated contrast | The typical orange colour of orange juice | Typical orange juice taste is little puckery | The typical case, no Chalk sense; Can accept | 1 |
| 2.CG-56 | The picture silkscreen is inhaled the faint yellow of sample; Slight oil film is arranged at the top | Slightly rare, the orange juice taste is not obvious | Slight Chalk mouthfeel can be accepted | 3 |
| 3.SF-1 | The picture silkscreen is inhaled the faint yellow of sample; There is slight oil film on the surface | The taste of orange juice is better than No. 2 | Soft and smooth, the butyrous mouthfeel is than other sample thickness; No Chalk mouthfeel; Can accept | 2 |
| 4.SP-1 | The typical orange colour of orange juice; The surface does not have oil film | Slightly rare, little puckery | Slight Chalk and powdery mouthfeel, unacceptable | 4 |
Embodiment 8-grain size analysis
The grain size analysis of particulate plant sterol compositions is following carrying out on Horiba LA-910 Particle Size Analyzer.Pulverous plant sterol particulate samples is shaken in sack with abundant mixing.On balance, put a 15mL conical tube and make its balance, and in the conical pipe of 15mL, add 0.05-0.1 gram sample.Add water to the 5mL scale of 15mL conical pipe.(EM Science CAS9002-93-1), and is placed on conical pipe in the ultra sonic bath to add 6 Triton X-100 with disposable pipet in the 15mL conical pipe.Stir the mixture with spatula after ultrasonic 1 minute, and then ultrasonic 4 minutes.4 minutes ultrasonic during with 15ml conical pipe vibration 3 times.Content in the 15ml conical pipe is transferred to the 7mL tissue grinder.Sample is smash 3 times with pestle.With disposable
In the liquid in half insertion tissue grinder of Pyrex pasteur pipet, take out pasteur pipet liquid.With liquid dispersions all in the pasteur pipet in containing the instrument sample room of 300mL deionized water.After sample liquid added the instrument sample room,, and obtain particle size distribution data with ultrasonic 1 minute of sample room.
Standard analysis
The titer of packing in advance (Duke Scientific Corp.0.5 μ m particle counter size standards or DukeScientific Corp.5.0 μ m particle counter size standards) is added the instrument sample room of containing the 100mL deionized water, and % is lower than 95% up to transmittance.With ultrasonic 1 minute of sample room.Obtain particle size distribution data then.
Embodiment 9-makes pulp and the particulate homogeneous composition of plant sterol and is dispersed in the test juice
In order to contain the 1 gram particulate orange juice of plant sterol (from concentrated fruit juice) among the every 240mL of below manufactured:
Make pulp
Weight %
Fructus Citri tangerinae pulp 24.30
Water 72.89
Plant sterol granule (for example, CG-522, SF-1) 2.81
Amount to 100.00
With bench top high shear mixer (PowerGen 1800D, Fisher Scientific) utilize high shear force (10,000rpm) with pulp, water and the premixing of sterol mixture 5 minutes.
Then in two stages under 4500/500psi the pulp of intimate mixing, water and sterol mixture (bench top homogenizer, model 15, APV Gaulin, Inc.).
Make the orange juice of single concentration
Weight %
Water 65.41
The pulp goods 16.46 that contain sterol
The orange juice 18.13 of freeze concentration
Amount to 100.00
Mentioned component is simply mixed.
These per 10 gram pulps (pure pulp (not adding water) is in weight in wet base) of filling a prescription can provide about 1 gram plant sterol granule.
Many embodiments of the present invention have been described.Yet should be appreciated that, under the situation that does not deviate from spirit and scope of the invention, can be used as many modifications.Therefore, other embodiment also within the scope of the appended claims.
Claims (83)
1. compositions, it contains one or more plant sterol granules, and wherein, described compositions display goes out particulate multimodal volume weighting of described one or more plant sterols or quality weighting particle size distribution (PSD);
Wherein, described compositions display goes out the particulate multimodal surface area of described one or more plant sterols weighting particle size distribution;
Wherein, in the time of in described compositions being dispersed in test juice, it has acceptable mouthfeel in described test juice.
2. compositions as claimed in claim 1 is characterized in that, described multimodal volume weighting or quality weighting particle size distribution show:
A) diameter at first peak of plant sterol granule is less than 2 microns, and the volume weighting mean diameter is about the 0.3-0.5 micron; With
B) diameter at second peak of plant sterol granule is about 35 microns of 2-, and wherein, the volume weighting mean diameter at described second peak is about the 8-12 micron.
3. compositions as claimed in claim 2 is characterized in that, described second peak accounts for about 65%-85% of described volume weighting or quality weighting particle size distribution; Described first peak accounts for about 15%-35% of described volume weighting or quality weighting particle size distribution.
4. compositions as claimed in claim 1 is characterized in that, described compositions display goes out the particulate multimodal surface area of described one or more plant sterols weighting particle size distribution.
5. compositions as claimed in claim 4 is characterized in that, described surface area weighting particle size distribution shows:
A) diameter at first peak of plant sterol granule is less than 2 microns; With
B) diameter at second peak of plant sterol granule is about 35 microns of 2-, and the surface area weighted average particle diameter at described second peak is about the 8-12 micron.
6. compositions as claimed in claim 5 is characterized in that, particulate first peak of described plant sterol accounts for about 78%-92% of described surface area weighting particle size distribution.
7. compositions as claimed in claim 5 is characterized in that, described diameter is about 0.5 micron or littler less than the surface area weighted average particle diameter at first peak of plant sterol granule of 2 microns.
8. compositions as claimed in claim 7 is characterized in that, described diameter is about 0.3 micron-0.5 micron less than the surface area weighted average particle diameter at first peak of plant sterol granule of 2 microns.
9. compositions as claimed in claim 8 is characterized in that, described diameter is about 0.4 micron less than the surface area weighted average particle diameter at first peak of plant sterol granule of 2 microns.
10. compositions as claimed in claim 4 is characterized in that, total specific surface area of described multimodal surface area weighting particle size distribution is greater than about 2m
2/ g.
11. compositions as claimed in claim 10 is characterized in that, total specific surface area of described multimodal surface area weighting particle size distribution is about 2.5-7m
2/ g.
12. compositions as claimed in claim 11 is characterized in that, total specific surface area of described multimodal surface area weighting particle size distribution is about 2.8-6.5m
2/ g.
13. compositions as claimed in claim 3 is characterized in that, in described volume weighting or quality weighting particle size distribution, diameter greater than 35 microns the particulate percent by volume of all plant sterols less than about 3%.
14. compositions as claimed in claim 13 is characterized in that, in described volume weighting or quality weighting particle size distribution, diameter greater than 35 microns the particulate percent by volume of all plant sterols less than about 0.5%.
15. compositions as claimed in claim 1 is characterized in that, described compositions is dispersed in the water-bearing media.
16. compositions as claimed in claim 1 is characterized in that, described compositions is an Aquo-composition.
17. compositions as claimed in claim 1 is characterized in that, described compositions is a powder composition.
18. compositions as claimed in claim 1 is characterized in that, described compositions is the Foods or drinks compositions.
19. compositions as claimed in claim 18, it is characterized in that described beverage composition for treating dental erosion is selected from juice, concentrated juice, coffee, tea, silkscreen suction, snow gram, bean milk, Rice ﹠ peanut milk, iced drink, beverage containing milk, replaces food and drink material, weight-reducing drinks and nutritional supplementation beverage.
20. compositions as claimed in claim 18, it is characterized in that, described food compositions is selected from bread, bakery, confection, ice cream, preserve, egg, egg succedaneum, ice cream, yoghourt, healthy complementary goods, for canteen product and nutriment.
21. a method of making particulate plant sterol compositions, described method comprises:
A) cooling plant sterol raw material; With
B) impact type or pulverize formula and grind described refrigerative plant sterol raw material.
22. method as claimed in claim 21 is characterized in that, described plant sterol raw material is made of one or more plant sterols substantially.
23. method as claimed in claim 21 is characterized in that, described plant sterol raw material does not contain emulsifying agent.
24. method as claimed in claim 21 is characterized in that, about 88%-100% of described plant sterol raw material weight is one or more plant sterols.
25. method as claimed in claim 24 is characterized in that, described plant sterol raw material comprises vitamin E and/or tocopherol.
26. method as claimed in claim 21 is characterized in that, described plant sterol raw material is cooled to pact-100 to-275 .
27. method as claimed in claim 26 is characterized in that, described plant sterol raw material is cooled to-175 to-250 approximately.
28. method as claimed in claim 27 is characterized in that, described plant sterol raw material is cooled to-225 approximately.
29. method as claimed in claim 21 is characterized in that, described plant sterol raw material cooled with liquid nitrogen.
30. method as claimed in claim 21 is characterized in that, described impact type or pulverize formula and grind and to carry out with gap mill.
31. method as claimed in claim 30 is characterized in that, the rotor-stator gap of described gap mill is about 0.025 " 0.05 ".
32. method as claimed in claim 31 is characterized in that, described rotor-stator gap is about 0.03 ".
33. method as claimed in claim 30 is characterized in that, uses the described impact type of described gap mill or pulverizes formula and grind and to carry out once.
34. method as claimed in claim 30 is characterized in that, the average end speed of described gap mill is about 110m/s-150m/s.
35. method as claimed in claim 34 is characterized in that, described average end speed is about 120-135m/s.
36. method as claimed in claim 30 is characterized in that, the temperature of the described particulate plant sterol compositions that draws off from described gap mill is about-25 to-275 .
37. method as claimed in claim 36 is characterized in that, the temperature of the described particulate plant sterol compositions that draws off from described gap mill is about-40 to-75 .
38. method as claimed in claim 37 is characterized in that, the temperature of the particulate plant sterol compositions that draws off from described gap mill is about-40 to-50 .
39. method as claimed in claim 21 is characterized in that, described plant sterol raw material is the lozenge form of the about 1mm-4mm of diameter.
40. method as claimed in claim 39 is characterized in that, the diameter of described lozenge is about 2mm.
41. method as claimed in claim 21, it is characterized in that impact type or pulverize formula and grind described refrigerative plant sterol raw material during one or more materials below existing: flowable, coloring agent, flavorant, vitamin, mineral, fibrous raw material, protein and nourishing additive agent.
42. method as claimed in claim 41 is characterized in that, described flowable is a sodium aluminosilicate.
43. method as claimed in claim 41 is characterized in that, described coloring agent is a beta-carotene.
44. method as claimed in claim 41 is characterized in that, described mineral is a calcium.
45. a method of making particulate plant sterol compositions, described method comprises:
A) be about 5-6 crust, outlet temperature in inlet pressure and grind the plant sterol raw material in less than the Hametag mill of about 100 .
46. method as claimed in claim 45 is characterized in that, described grinding is to carry out under the temperature of about 60-80 .
47. method as claimed in claim 45 is characterized in that, the grinding in the described Hametag mill is carried out once.
48. method as claimed in claim 45 is characterized in that, described plant sterol raw material is made of one or more plant sterols substantially.
49. method as claimed in claim 45 is characterized in that, described plant sterol raw material does not contain emulsifying agent.
50. method as claimed in claim 45 is characterized in that, about 88%-100% of described plant sterol raw material weight is one or more plant sterols.
51. method as claimed in claim 50 is characterized in that, described plant sterol raw material comprises vitamin E and/or tocopherol.
52. method as claimed in claim 45, it is characterized in that, below existing, grind described refrigerative plant sterol raw material during one or more materials: flowable, coloring agent, flavorant, vitamin, mineral, fibrous raw material, protein and nourishing additive agent.
53. method as claimed in claim 52 is characterized in that, described flowable is a sodium aluminosilicate.
54. method as claimed in claim 52 is characterized in that, described coloring agent is a beta-carotene.
55. method as claimed in claim 52 is characterized in that, described mineral is a calcium.
56. method as claimed in claim 45 is characterized in that, described plant sterol raw material is the lozenge form of the about 1mm-4mm of diameter.
57. method as claimed in claim 56 is characterized in that, the diameter of described lozenge is about 2mm.
58. particulate plant sterol compositions made from the described method of claim 21.
59. particulate plant sterol compositions made from the described method of claim 45.
60. a method of making the particulate plant sterol compositions aqueous dispersion, described method comprise particulate plant sterol compositions is mixed with hydrous material, wherein said particulate plant sterol compositions demonstrates multimodal surface area weighting particle size distribution.
61. method as claimed in claim 60 is characterized in that, described multimodal surface area weighting particle size distribution shows:
A) diameter at first peak of plant sterol granule is less than 2 microns; With
B) diameter at second peak of plant sterol granule is about 35 microns of 2-, and the surface area weighted average particle diameter at described second peak is about the 8-12 micron.
62. method as claimed in claim 61 is characterized in that, particulate first peak of described plant sterol accounts for about 78%-92% of described surface area weighting particle size distribution.
63. method as claimed in claim 61 is characterized in that, described diameter is about 0.5 micron less than the surface area weighted average particle diameter at first peak of plant sterol granule of 2 microns.
64. method as claimed in claim 61 is characterized in that, described diameter is about 0.3 micron-0.5 micron less than the surface area weighted average particle diameter at first peak of plant sterol granule of 2 microns.
65., it is characterized in that described diameter is about 0.4 micron less than the surface area weighted average particle diameter at first peak of plant sterol granule of 2 microns as the described method of claim 64.
66. method as claimed in claim 61 is characterized in that, total specific surface area of described multimodal surface area weighting particle size distribution is greater than about 2m
2/ g.
67., it is characterized in that total specific surface area of described multimodal surface area weighting particle size distribution is about 2.5-7m as the described method of claim 66
2/ g.
68., it is characterized in that total specific surface area of described multimodal surface area weighting particle size distribution is about 2.8-6.5m as the described method of claim 67
2/ g.
69. method as claimed in claim 61 is characterized in that, described hydrous material is selected from water, juice, concentrated juice, coffee, tea, egg mixture, ice cream, yoghourt, bean milk and beverage containing milk.
70. a compositions that contains the dispersion of particulate plant sterol compositions in hydrous material, wherein said particulate plant sterol compositions demonstrate multimodal surface area weighting particle size distribution, described multimodal surface area weighting particle size distribution shows:
A) diameter at first peak of plant sterol granule is less than 2 microns; With
B) diameter at second peak of plant sterol granule is about 35 microns of 2-, and the surface area weighted average particle diameter at wherein said second peak is about the 8-12 micron.
71., it is characterized in that described compositions does not have or have only slight detectable Chalk mouthfeel as the described compositions of claim 70.
72. method as claimed in claim 60 is characterized in that, described particulate plant sterol compositions is mixed with described hydrous material to avoid causing unwanted attribute of sensation to described aqueous dispersion substantially.
73., it is characterized in that described unwanted attribute of sensation is Chalk, grit, drying or powdery mouthfeel as the described method of claim 72.
74. a method of making the dispersion of particulate plant sterol compositions, described method comprises particulate plant sterol compositions with the pulp homogenizing.
75., it is characterized in that described homogenizing step also comprises water as the described method of claim 74.
76. as the described method of claim 75, it is characterized in that, before described homogenizing, described pulp, described water and described particulate plant sterol compositions mixed by high shear force.
77., it is characterized in that described homogenizing step carries out in two stages as the described method of claim 74.
78., it is characterized in that compare the described second homogenizing stage, the described first homogenizing stage carries out as the described method of claim 77 under the pound/square inch of bigger value.
79., it is characterized in that described pulp is the Citrus pulp that is selected from Fructus Citri tangerinae pulp, Fructus Citri Limoniae pulp, Citrus aurantium Linn. pulp and grapefruit pulp as the described method of claim 74.
80., it is characterized in that described water as the described method of claim 75: the weight ratio of pulp is about 1: 1-4: 1.
81., it is characterized in that described particulate plant sterol compositions accounts for about 1%-10% of described pulp, described water and described particulate plant sterol compositions gross weight as the described method of claim 75.
82. a method of making the particulate aqueous dispersion of plant sterol, described method comprise that the uniform homogeneous blend that will contain pulp and particulate plant sterol compositions mixes with water-bearing media.
83., it is characterized in that described water-bearing media is juice or concentrated juice as the described method of claim 82.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2004/003937 WO2005087200A1 (en) | 2004-02-10 | 2004-02-10 | Particulate plant sterol compositions |
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| Publication Number | Publication Date |
|---|---|
| CN1913874A true CN1913874A (en) | 2007-02-14 |
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| CNA2004800414463A Pending CN1913874A (en) | 2004-02-10 | 2004-02-10 | Particulate plant sterol compositions |
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|---|---|
| EP (1) | EP1713447A4 (en) |
| JP (1) | JP2007524415A (en) |
| CN (1) | CN1913874A (en) |
| AU (1) | AU2004317157A1 (en) |
| BR (1) | BRPI0418516A (en) |
| CA (1) | CA2554547A1 (en) |
| IL (1) | IL177070A0 (en) |
| WO (1) | WO2005087200A1 (en) |
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| CN102630754A (en) * | 2012-04-18 | 2012-08-15 | 内蒙古蒙牛乳业（集团）股份有限公司 | Compound liquid dairy product with function of assisting in reducing blood fat and preparation method thereof |
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| US7335389B2 (en) | 2002-06-12 | 2008-02-26 | The Coca-Cola Company | Beverages containing plant sterols |
| US7306819B2 (en) | 2002-06-12 | 2007-12-11 | The Coca-Cola Company | Beverages containing plant sterols |
| JP4717413B2 (en) * | 2004-10-22 | 2011-07-06 | 森永乳業株式会社 | Composition for improving lipid metabolism |
| CL2009000409A1 (en) * | 2009-02-23 | 2009-05-04 | Rojas Alejandro Markovits | Process to obtain a dispersion of solid phytosterols in water. |
| US8673382B2 (en) | 2009-11-23 | 2014-03-18 | Tropicana Products, Inc. | Thick juice beverages |
| US10334870B2 (en) | 2010-10-07 | 2019-07-02 | Tropicana Products, Inc. | Processing of whole fruits and vegetables, processing of side-stream ingredients of fruits and vegetables, and use of the processed fruits and vegetables in beverage and food products |
| MX2015009165A (en) | 2013-02-15 | 2015-11-09 | Pepsico Inc | Preparation and incorporation of co-products into beverages to enhance nutrition and sensory attributes. |
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|---|---|---|---|---|
| US4195084A (en) * | 1977-01-07 | 1980-03-25 | Eli Lilly And Company | Taste-stable aqueous pharmaceutical suspension of tall oil sitosterols and a method for the preparation thereof |
| US4897224A (en) * | 1985-03-05 | 1990-01-30 | Morinaga Milk Industry Co., Ltd. | Method for producing ferulyl stanol derivatives |
| FI105887B (en) * | 1996-09-27 | 2000-10-31 | Suomen Sokeri Oy | Products containing plant sterol for use in food and therapeutic applications, process for their preparation and their use |
| AU2426500A (en) * | 1999-02-03 | 2000-08-25 | Forbes Medi-Tech Inc. | Method of preparing microparticles of phytosterols or phytostanols |
| US6391370B1 (en) * | 1999-11-12 | 2002-05-21 | Kraft Foods, Inc. | Micromilling plant sterols and emulsifiers |
| KR20020026053A (en) * | 2000-09-30 | 2002-04-06 | 노승권 | Method of dispersing plant sterol for a beverage and beverage containing the same |
-
2004
- 2004-02-10 BR BRPI0418516-1A patent/BRPI0418516A/en not_active IP Right Cessation
- 2004-02-10 CA CA002554547A patent/CA2554547A1/en not_active Abandoned
- 2004-02-10 JP JP2006552090A patent/JP2007524415A/en active Pending
- 2004-02-10 AU AU2004317157A patent/AU2004317157A1/en not_active Abandoned
- 2004-02-10 CN CNA2004800414463A patent/CN1913874A/en active Pending
- 2004-02-10 WO PCT/US2004/003937 patent/WO2005087200A1/en active Application Filing
- 2004-02-10 EP EP04709929A patent/EP1713447A4/en not_active Withdrawn
-
2006
- 2006-07-25 IL IL177070A patent/IL177070A0/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102630754A (en) * | 2012-04-18 | 2012-08-15 | 内蒙古蒙牛乳业（集团）股份有限公司 | Compound liquid dairy product with function of assisting in reducing blood fat and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005087200A1 (en) | 2005-09-22 |
| EP1713447A4 (en) | 2008-07-02 |
| JP2007524415A (en) | 2007-08-30 |
| BRPI0418516A (en) | 2007-05-15 |
| EP1713447A1 (en) | 2006-10-25 |
| IL177070A0 (en) | 2006-12-10 |
| CA2554547A1 (en) | 2005-09-22 |
| AU2004317157A1 (en) | 2005-09-22 |
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