CN1907025B - 除草组合物 - Google Patents
除草组合物 Download PDFInfo
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- CN1907025B CN1907025B CN2006101075458A CN200610107545A CN1907025B CN 1907025 B CN1907025 B CN 1907025B CN 2006101075458 A CN2006101075458 A CN 2006101075458A CN 200610107545 A CN200610107545 A CN 200610107545A CN 1907025 B CN1907025 B CN 1907025B
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- 0 CCCC(C)(CC1)C*=**1NCCC Chemical compound CCCC(C)(CC1)C*=**1NCCC 0.000 description 8
- FOXFZRUHNHCZPX-UHFFFAOYSA-N CC(C)(C)C(C(N1N)=O)=NN=C1SC Chemical compound CC(C)(C)C(C(N1N)=O)=NN=C1SC FOXFZRUHNHCZPX-UHFFFAOYSA-N 0.000 description 1
- FMGZEUWROYGLAY-UHFFFAOYSA-N C[n](c(S(NC(Nc1nc(OC)cc(OC)n1)=O)(=O)=O)c1C(OC)=O)nc1Cl Chemical compound C[n](c(S(NC(Nc1nc(OC)cc(OC)n1)=O)(=O)=O)c1C(OC)=O)nc1Cl FMGZEUWROYGLAY-UHFFFAOYSA-N 0.000 description 1
- LTQJQRDLBLZXAK-UHFFFAOYSA-N Cc1c(C(OCc2ccccc2)=O)[s]c(Cl)n1 Chemical compound Cc1c(C(OCc2ccccc2)=O)[s]c(Cl)n1 LTQJQRDLBLZXAK-UHFFFAOYSA-N 0.000 description 1
- WTBPIQNDWIRWMM-BOPFTXTBSA-N FC(/C(/c(cc1)ccc1Cl)=N\OCC1[O]=CCO1)(F)F Chemical compound FC(/C(/c(cc1)ccc1Cl)=N\OCC1[O]=CCO1)(F)F WTBPIQNDWIRWMM-BOPFTXTBSA-N 0.000 description 1
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- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
除草组合物，所述组合物除了包含常用惰性制剂助剂以外，还包含：a)式(I)化合物，其中取代基如权利要求1中所定义；和b)协同有效量的一种或多种式2.1-2.51化合物。本发明组合物还可以包含安全剂。
Description
本申请为中国发明专利申请No.01804089.6的分案申请，其申请日为2001年1月23日，优先权日为2000年1月25日(CH 139/2000)和2000年6月9日(CH 1150/2000)。
本发明涉及新的除草组合物，其中包含适于选择性地控制有用植物农作物例如玉米农作物中的杂草的除草活性组分组合。本发明还涉及控制有用植物农作物中的杂草的方法，以及新的组合物在这样的用途中的应用。
式I化合物
其中取代基的定义在下文中给出，
具有除草活性。
令人惊奇的是，现在已经发现，不定量的活性组分、即不定量的式I活性组分与一种或多种下文所列出的已知的、并且某些可商购获得的式2.1-2.51活性组分的组合表现出协同作用，能够控制尤其是在有用植物农作物中生长的大多数杂草(既能控制芽前的杂草，也能控制苗后的杂草)。
因此，本发明提供了用于选择性地控制杂草的新的协同组合物，所述组合物除了含有常规惰性制剂助剂以外，还含有下列组分的混合物作为活性组分：
a)除草有效量的式I化合物或其农业可接受盐
其中每个R独立地为氢、C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基、C1-C6卤代烷硫基、C1-C6卤代烷基亚磺酰基、C1-C6卤代烷基磺酰基、C1-C6烷氧基羰基、C1-C6烷基羰基、C1-C6烷基氨基、二(C1-C6烷基)氨基、C1-C6烷基氨基磺酰基、二(C1-C6烷基)氨基磺酰基、-N(R1)-S-R2、-N(R3)-SO-R4、-N(R5)-SO2-R6、硝基、氰基、卤素、羟基、氨基、苄硫基、苄基亚磺酰基、苄基磺酰基、苯基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基；其中所述苯基自身可被下列基团单取代、二取代或三取代：C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R45、NR46R47、卤素、氰基、硝基、苯基或苄硫基，其中后面所述的苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；
或者每个R独立地为5-10元单环或稠合二环系，所述环系可以是芳环或部分饱和环，并且可以含有1-4个选自氮、氧和硫的杂原子；其中所述环系直接与吡啶环连接，或者经由C1-C4亚烷基与吡啶环连接，并且每个环系不可以含有2个以上的氧原子，不可以含有2个以上的硫原子，所述环系自身可被下列基团单取代、二取代或三取代：C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R7、NR8R9、卤素、氰基、硝基、苯基或苄硫基，其中所述苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代，并且在杂环中的氮上的取代基不是卤素；
或者每个R独立地为C1-C4烷氧基-C1-C4烷基或C1-C4烷氧基-C1-C4烷氧基-C1-C4烷基；
m是1、2、3或4；
R1、R3和R5分别独立地为氢或C1-C6烷基；
R2是NR10R11、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；
R4是NR12R13、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；
R6是NR14R15、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；
R7和R45分别独立地为C1-C3烷氧基、C2-C4烷氧基羰基、C1-C3烷硫基、C1-C3烷基亚磺酰基、C1-C3烷基磺酰基或苯基，其中所述苯基自身可被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；
R8、R10、R12、R14和R46分别独立地为氢或C1-C6烷基；
R9、R11、R13、R15和R47分别独立地为C1-C6烷基或C1-C6烷氧基；
Q是基团Q1
其中R16、R17、R18和R19分别独立地为氢、羟基、C1-C4烷基、C2-C6链烯基、C2-C6炔基、C1-C4烷氧基羰基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-NHS(O)2、C1-C4卤代烷基、-NH-C1-C4烷基、-N(C1-C4烷基)2、C1-C6烷氧基、氰基、硝基、卤素、或苯基，其中所述苯基自身可被下列基团取代：C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者R16、R17、R18和R19当中的两个相邻取代基形成C2-C6亚烷基桥；
R20是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R21R22N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代：C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；且R21和R22分别独立地为氢或C1-C4烷基；
或者是基团Q2
其中R23是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4-链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R24R25N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代：C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；
R24和R25分别独立地为氢或C1-C4烷基；且
Y是氧、硫、化学键或C1-C4亚烷基桥；
或者是Q3
其中R44、R37、R38和R39分别独立地为氢、C1-C6烷基、C1-C6卤代烷基、C2-C6链烯基、C2-C6炔基、C1-C6烷氧基羰基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6烷基-NHS(O)2、C1-C6烷基氨基、二(C1-C6烷基)氨基、羟基、C1-C6烷氧基、C3-C6链烯氧基、C3-C6炔氧基、羟基-C1-C6烷基、C1-C4烷基-磺酰基氧基-C1-C6烷基、甲苯磺酰基氧基-C1-C6烷基、卤素、氰基、硝基、苯基、或被下列基团取代的苯基：C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-S(O)2O、C1-C6卤代烷硫基、C1-C6卤代烷基亚磺酰基、C1-C6卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C6烷硫基-N(C1-C4烷基)、C1-C6烷基亚磺酰基-N(C1-C4烷基)、C1-C6烷基磺酰基-N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者相邻的R44和R37或R38和R39一起为C3-C6亚烷基；
W是氧、硫、亚磺酰基、磺酰基、-CR41R42-、-C(O)-或-NR43-；
R41是氢、C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基-C1-C4烷基、C1-C4烷硫基-C1-C4烷基、C1-C4烷基羰基氧基-C1-C4烷基、C1-C4烷基磺酰基氧基-C1-C4烷基、甲苯磺酰基氧基-C1-C4烷基、二(C1-C3烷氧基烷基)甲基、二(C1-C3烷硫基烷基)甲基、(C1-C3烷氧基烷基)-(C1-C3烷硫基烷基)甲基、C3-C5氧杂环烷基、C3-C5硫杂环烷基、C3-C4二氧杂环烷基、C3-C4二硫杂环烷基、C3-C4氧杂硫杂环烷基、甲酰基、C1-C4烷氧基羰基、或苯基，所述苯基自身可被下列基团取代：C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C6烷硫基-N(C1-C4烷基)、C1-C6烷基亚磺酰基-N(C1-C4烷基)、C1-C6烷基磺酰基-N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者R42与R39一起为C1-C6亚烷基；
R42是氢、C1-C4烷基或C1-C4卤代烷基；
R40是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R96R97N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代：C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；R96和R97分别独立地为氢或C1-C4烷基；
R43是氢、C1-C4烷基、C1-C4烷氧基羰基、或苯基，其中所述苯基自身可被下列基团取代：C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；
或者是基团Q4
其中R30是羟基、O-M+、卤素、C1-C12烷氧基、C1-C12烷基羰基氧基、C2-C4链烯基羰基氧基、C3-C6环烷基羰基氧基、C1-C12烷氧基羰基氧基、C1-C12烷基羰基氧基、R31R32N-C(O)O、C1-C12烷硫基、C1-C12烷基亚磺酰基、C1-C12烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C2-C12链烯硫基、C2-C12链烯基亚磺酰基、C2-C12链烯基磺酰基、C2-C12卤代链烯硫基、C2-C12卤代链烯基亚磺酰基、C2-C12卤代链烯基磺酰基、C2-C12炔硫基、C2-C12炔基亚磺酰基、C2-C12炔基磺酰基、C1-C4烷基-S(O)2O、苯基-S(O)2O、(C1-C4烷氧基)2P(O)O、C1-C4烷基(C1-C4烷氧基)P(O)O、H(C1-C4烷氧基)P(O)O、C1-C12-烷基-S(CO)O、苄氧基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基，其中所述苯基自身可被下列基团取代：C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基或氰基；且
R31和R32分别独立地为氢或C1-C4烷基；
R33和R34分别独立地为氢、羟基、C1-C4烷基、C2-C6链烯基、C2-C6炔基、C1-C4烷氧基羰基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-NHS(O)2、C1-C4卤代烷基、-NH-C1-C4烷基、-N(C1-C4烷基)2、C1-C6烷氧基、氰基、硝基、卤素、或苯基，其中所述苯基自身可被下列基团取代：C1-C4烷基、C1-C4卤代烷基、C1-C4-烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基、COOH或氰基；或者
R33和R34一起形成C2-C6亚烷基桥；且
R35是氢、C1-C4烷基、C1-C4烷氧基羰基、或苯基，所述苯基自身可被下列基团取代：C1-C4烷基、C1-C4卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基羰基、C1-C4烷氧基羰基、氨基、C1-C4烷基氨基、二(C1-C4烷基)氨基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4烷基-S(O)2O、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4卤代烷基-S(O)2O、C1-C4烷基-S(O)2NH、C1-C4烷基-S(O)2N(C1-C4烷基)、卤素、硝基、COOH或氰基；
或者是基团Q5
其中Z是硫、SO或SO2；
R01是氢、C1-C8烷基、被下列基团取代的C1-C8烷基：卤素、C1-C4烷氧基、C1-C4烷硫基、C1-C4烷基磺酰基、C1-C4烷基亚磺酰基、羟基、氰基、硝基、-CHO、-CO2R02、-COR03、-COSR04、-NR05R06、CONR036R037、或苯基，所述苯基自身可被下列基团取代：C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7-环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR025R026、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR015CO2R027；
或者R01是C2-C8链烯基或被下列基团取代的C2-C8链烯基：卤素、C1-C4烷氧基、C1-C4烷硫基、C1-C4烷基磺酰基、C1-C4烷基亚磺酰基、-CONR032R033、氰基、硝基、-CHO、-CO2R038、-COR039、-COS-C1-C4烷基、-NR034R035、或苯基，所述苯基自身可被下列基团取代：C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR040R041、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR043CO2R042；
或者R01是C3-C6炔基或被下列基团取代的C3-C6炔基：卤素、C1-C4卤代烷基、氰基、-CO2R044、或苯基，所述苯基自身可被下列基团取代：C1-C4烷基、C1-C6卤代烷基、C1-C4-烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4-烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR028R029、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR031CO2R030；
或者R01是C3-C7环烷基或被下列基团取代的C3-C7环烷基：C1-C4烷基、C1-C4烷氧基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、或苯基，所述苯基自身可被下列基团取代：卤素、硝基、氰基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷硫基、C1-C4卤代烷硫基、C1-C4烷基或C1-C4卤代烷基；或者
R01是C1-C4亚烷基-C3-C7环烷基、苯基、或被下列基团取代的苯基：C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4-烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR045R046、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基或-NR048CO2R047；或者R01是C1-C4亚烷基苯基、COR07或4-6元杂环基；
R02、R038、R044和R066分别独立地为氢、C1-C4烷基、苯基、或被下列基团取代的苯基：C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)-SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR049R050、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、-C1-C4-烷基苯基或-NR052CO2R053；
R03、R039和R067分别独立地为C1-C4烷基、苯基、或被下列基团取代的苯基：C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)-SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR068R054、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、-(CH2)t-苯基或-NR056CO2R055；
R04是C1-C4烷基；
R05是氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基、C3-C7环烷基、苯基、或被下列基团取代的苯基：C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4烷基、(C1-C4烷基亚磺酰基-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2H、N(C3-C6炔基)-SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2H、N(C3-C7环烷基)-SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR057R058、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR060CO2R059；
R06是氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基、C3-C7环烷基、苯基、或被下列基团取代的苯基：C1-C4烷基、C1-C6卤代烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C2-C6链烯基、C3-C6炔基、C3-C6链烯氧基、C3-C6炔氧基、卤素、硝基、氰基、-COOH、COOC1-C4烷基、COO苯基、C1-C4烷氧基、苯氧基、(C1-C4烷氧基)-C1-C4烷基、(C1-C4烷硫基)-C1-C4-烷基、(C1-C4烷基亚磺酰基)-C1-C4烷基、(C1-C4烷基磺酰基)-C1-C4烷基、NHSO2-C1-C4烷基、NHSO2-苯基、N(C1-C6烷基)SO2-C1-C4烷基、N(C1-C6烷基)SO2-苯基、N(C2-C6链烯基)-SO2-C1-C4烷基、N(C2-C6链烯基)SO2-苯基、N(C3-C6炔基)SO2-C1-C4烷基、N(C3-C6炔基)SO2-苯基、N(C3-C7环烷基)SO2-C1-C4烷基、N(C3-C7环烷基)SO2-苯基、N(苯基)SO2-C1-C4烷基、N(苯基)SO2-苯基、OSO2-C1-C4烷基、CONR061R062、OSO2-C1-C4卤代烷基、OSO2-苯基、C1-C4烷硫基、C1-C4卤代烷硫基、苯硫基、C1-C4烷基磺酰基、C1-C4卤代烷基磺酰基、苯基磺酰基、C1-C4烷基亚磺酰基、C1-C4卤代烷基亚磺酰基、苯基亚磺酰基、C1-C4亚烷基苯基或-NR064CO2R063；
R07是苯基、C1-C4烷基、C1-C4烷氧基或-NR08R09；
R08和R09分别独立地为C1-C4烷基、苯基、或被下列基团取代的苯基：卤素、硝基、氰基、C1-C4烷基、C1-C4烷氧基、C1-C4烷硫基、-CO2R066、-COR067、C1-C4烷基磺酰基、C-C4烷基亚磺酰基或C1-C4卤代烷基；或者R08和R09一起形成可被氧、NR065或S间隔的5-元或6-元环；
R015、R031、R043、R048、R052、R056、R060和R064分别独立地为氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基或C3-C7环烷基；
R025、R026、R027、R028、R029、R030、R032、R033、R034、R035、R036、R037、R040、R041、R042、R045、R046、R047、R049、R050、R053、R054、R055、R057、R058、R059、R061、R062、R053、R065和R068分别独立地为氢、C1-C4烷基、C2-C6链烯基、C3-C6炔基、C3-C7环烷基、苯基、或被下列基团取代的苯基：卤素、硝基、氰基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷硫基、C1-C4卤代烷硫基、C1-C4烷基或C1-C4卤代烷基；且
R36是C1-C4烷基、C1-C4卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C3-C6环烷基、或被下列基团取代的C3-C6环烷基：卤素、C1-C4烷基、C1-C4卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C4烷氧基羰基、C1-C4烷硫基、C1-C4烷基亚磺酰基、C1-C4烷基磺酰基、C1-C4卤代烷硫基、C1-C4卤代烷基亚磺酰基、C1-C4卤代烷基磺酰基、C1-C4烷基羰基、二(C1-C4烷基)氨基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4烷基-S(O)2O、C1-C4卤代烷基-S(O)2O、或苯基，所述苯基自身可被下列基团取代：卤素、C1-C4烷基、C1-C4卤代烷基、C3-C6链烯基、C3-C6炔基、氰基、硝基或COOH；
和
b)协同有效量的一种或多种选自下列的化合物：
式2.1化合物
其中R51是CH2-OMe、乙基或氢；
R52是氢，或者R51与R52一起形成基团-CH＝CH-CH＝CH-；
和式2.2化合物
其中R53是乙基，R54是甲基或乙基，且R55是-CH(Me)-CH2OMe、<S>-CH(Me)-CH2OMe、CH2OMe或CH2O-CH2CH3；
和式2.3化合物
其中R56是CH(Me)-CH2OMe或<S>CH(Me)-CH2OMe；
和式2.4化合物
其中R57是氯、甲氧基或甲硫基，R58是乙基，且R59是乙基、异丙基、-C(CN)(CH3)-CH3或叔丁基；
和式2.5化合物
其中R60是乙基或正丙基，R61是COO-1/2 Ca++、-CH2-CH(Me)S-CH2CH3或基团
且X是氧、N-O-CH2CH3或N-O-CH2CH＝CH-Cl；
和式2.6化合物
其中R62是氢、甲氧基或乙氧基，R63是氢、甲基、甲氧基或氟，R64是COOMe、氟或氯，R65是氢或甲基，Y是次甲基、C-F或氮，Z是次甲基或氮，且R66是氟或氯；
和式2.7化合物
其中R67是氢或-C(O)-S-正辛基；
和式2.8化合物
其中R68是溴或碘；
和式2.9化合物
其中R69是氯或硝基；
和式2.10化合物
其中R70是氟或氯，且R71是-CH2-CH(Cl)-COOCH2CH3或-NH-SO2Me；
和式2.11化合物
其中R72是三氟甲基或氯；
和式2.12化合物
其中R73是NH2或<S>NH2；
和式2.13化合物
其中Y1是氮、次甲基、NH-CHO或N-Me，Y2是氮、次甲基或C-I，Y3是次甲基，Y4是次甲基，或者Y3和Y4一起是硫或C-Cl，Y5是氮或次甲基，Y6是甲基、二氟甲氧基、三氟甲基或甲氧基，Y7是甲氧基或二氟甲氧基，且R74是CONMe2、COOMe、COOC2H5、三氟甲基、CH2-CH2CF3或SO2CH2CH3，或其钠盐(“Me”是甲基)；
和式2.13.c化合物
和式2.14化合物
和式2.15化合物
和式2.16化合物
和式2.17化合物
和式2.18化合物
和式2.19化合物
和式2.20化合物
和式2.21化合物
和式2.22化合物
和式2.23化合物
和式2.24化合物
和式2.25化合物
和式2.26化合物
和式2.27化合物
和式2.28化合物
和式2.29化合物
和式2.30化合物
和式2.31化合物
和式2.32化合物
和式2.33化合物
和式2.36化合物
和式2.37化合物
和式2.38化合物
和式2.39化合物
和式2.40化合物
和式2.41化合物
和式2.42化合物
和式2.43化合物
和式2.44化合物
和式2.45化合物
和式2.46化合物
和式2.47化合物
和式2.48化合物
和式2.49化合物
和式2.50化合物
和式2.51化合物
在上式中，“Me”是甲基。在取代基定义中提及的烷基可以是直链或支链，并且是例如甲基、乙基、正丙基、异丙基、正丁基、仲丁基、异丁基、叔丁基、戊基、己基、庚基、辛基、壬基、癸基、十一烷基和十二烷基及其支链异构体。烷氧基、链烯基和炔基衍生自上述烷基。链烯基和炔基可具有一个或一个以上的不饱和键。
亚烷基可以被一个或多个甲基取代；这样的亚烷基优选未取代。这也适用于所有含有C3-C5环烷基-、C3-C5氧杂环烷基-、C3-C5硫杂环烷基-、C3-C4二氧杂环烷基-、C3-C4二硫杂环烷基-、C3-C4氧硫杂环烷基-和N(CH2)-的基团。
卤素一般是氟、氯、溴或碘。这相应地适用于在其它定义例如卤代烷基或卤代苯基中出现的卤素。
具有1-6个碳原子链长的卤代烷基是例如氟甲基、二氟甲基、三氟甲基、氯甲基、二氯甲基、三氯甲基、2，2，2-三氟乙基、2-氟乙基、2-氯乙基、五氟乙基、1，1-二氟-2，2，2-三氯乙基、2，2，3，3-四氟乙基和2，2，2-三氯乙基、五氟乙基、七氟正丙基、五氟正己基；在R2、R3和尤其是R5的定义中的卤代烷基优选为三氯甲基、二氯氟甲基、二氟氯甲基、二氟甲基、三氟甲基、五氟乙基或七氟正丙基。
合适的卤代链烯基包括被卤素取代一次或多次的链烯基，卤素是氟、氯、溴或碘，尤其是氟或氯，例如2，2-二氟-1-甲基乙烯基、3-氟丙烯基、3-氯丙烯基、3-溴丙烯基、2，3，3-三氟丙烯基、2，3，3-三氯丙烯基和4，4，4-三氟丁-2-烯-1-基。优选的被卤素取代1次、2次或3次的C2-C12链烯基是链长为2-5个碳原子的那些。合适的卤代炔基包括例如被卤素取代一次或多次的炔基，卤素是溴或碘，和尤其是氟或氯，例如3-氟丙炔基、3-氯丙炔基、3-溴丙炔基、3，3，3-三氟丙炔基和4，4，4-三氟-丁-2-炔-1-基。优选的被卤素取代1次、2次或3次的炔基是链长为2-5个碳原子的那些。
烷氧基优选具有1-6个碳原子的链长。烷氧基是例如甲氧基、乙氧基、丙氧基、异丙氧基、正丁氧基、异丁氧基、仲丁氧基或叔丁氧基或戊氧基或己氧基异构体，优选甲氧基和乙氧基。烷基羰基优选为乙酰基或丙酰基。烷氧基羰基是例如甲氧基羰基、乙氧基羰基、丙氧基羰基、异丙氧基羰基、正丁氧基羰基、异丁氧基羰基、仲丁氧基羰基或叔丁氧基羰基，优选甲氧基羰基、乙氧基羰基或叔丁氧基羰基。卤代烷氧基优选具有1-8个碳原子的链长。
卤代烷氧基是例如氟甲氧基、二氟甲氧基、三氟甲氧基、2，2，2-三氟乙氧基、1，1，2，2-四氟乙氧基、2-氟乙氧基、2-氯乙氧基、2，2-二氟乙氧基或2，2，2-三氯乙氧基，优选二氟甲氧基、2-氯乙氧基或三氟甲氧基。
烷硫基优选具有1-8个碳原子的链长。
烷硫基是例如甲硫基、乙硫基、丙硫基、异丙硫基、正丁硫基、异丁硫基、仲丁硫基或叔丁硫基，优选为甲硫基或乙硫基。
烷基亚磺酰基是例如甲基亚磺酰基、乙基亚磺酰基、丙基亚磺酰基、异丙基亚磺酰基、正丁基亚磺酰基、异丁基亚磺酰基、仲丁基亚磺酰基或叔丁基亚磺酰基，优选为甲基亚磺酰基或乙基亚磺酰基。
烷基磺酰基是例如甲基磺酰基、乙基磺酰基、丙基磺酰基、异丙基磺酰基、正丁基磺酰基、异丁基磺酰基、仲丁基磺酰基或叔丁基磺酰基，优选为甲基磺酰基或乙基磺酰基。
烷基氨基是例如甲基氨基、乙基氨基、正丙基氨基、异丙基氨基或丁基氨基异构体。二烷基氨基是例如二甲基氨基、甲基乙基氨基、二乙基氨基、正丙基甲基氨基、二丁基氨基或二异丙基氨基。烷基氨基优选具有1-4个碳原子的链长。烷氧基烷基优选具有1-6个碳原子的链长。烷氧基烷基是例如甲氧基甲基、甲氧基乙基、乙氧基甲基、乙氧基乙基、正丙氧基甲基、正丙氧基乙基、异丙氧基甲基或异丙氧基乙基。烷硫基烷基优选具有1-6个碳原子的链长。烷硫基烷基是例如甲硫基甲基、甲硫基乙基、乙硫基甲基、乙硫基乙基、正丙硫基甲基、正丙硫基乙基、异丙硫基甲基、异丙硫基乙基、丁硫基甲基、丁硫基乙基或丁硫基丁基。
环烷基优选具有3-6个环碳原子，并且可以被一个或多个甲基取代；它们优选未取代，例如环丙基、环丁基、环戊基或环己基。苯基，包括作为取代基例如苯氧基、苄基、苄氧基、苯甲酰基、苯硫基、苯基烷基、苯氧基烷基或甲苯磺酰基的一部分的苯基可以是单取代或多取代形式，对于这种情况，取代基可以按照需要在邻位、间位和/或对位。
本发明还包括式I化合物可以与胺、碱金属和碱土金属碱或季铵碱形成的盐。在作为盐形成剂使用的碱金属和碱土金属氢氧化物当中，可特别提及氢氧化锂、氢氧化钠、氢氧化钾、氢氧化镁和氢氧化钙，尤其是氢氧化钠和氢氧化钾。
适用于形成铵盐的胺的实例是氨以及伯、仲和叔C1-C18烷基案、C1-C4羟基烷基胺和C2-C4烷氧基烷基胺，例如甲基胺、乙基胺、正丙基胺、异丙基胺、四种丁基胺异构体、正戊基胺、异戊基胺、己基胺、庚基胺、辛基胺、壬基胺、癸基胺、十五烷基胺、十六烷基胺、十七烷基胺、十八烷基胺、甲基乙基胺、甲异丙基胺、甲基己基胺、甲基壬基胺、甲基十五烷基胺、甲基十八烷基胺、乙基丁基胺、乙基庚基胺、乙基辛基胺、己基庚基胺、己基辛基胺、二甲基胺、二乙基胺、二-正丙基胺、二异丙基胺、二-正丁基胺、二正戊基胺、二异戊基胺、二己基胺、二庚基胺、二辛基胺、乙醇胺、正丙醇胺、异丙醇胺、N，N-二乙醇胺、N-乙基丙醇胺、N-丁基乙醇胺、烯丙基胺、正丁烯基-2-胺、正戊烯基-2-胺、2，3-二甲基丁烯基-2-胺、二丁烯基-2-胺、正己烯基-2-胺、丙二胺、三甲基胺、三乙基胺、三正丙基胺、三异丙基胺、三正丁基胺、三异丁基胺、三仲丁基胺、三正戊基胺、甲氧基乙基胺和乙氧基乙基胺；杂环胺例如吡啶、喹啉、异喹啉、吗啉、哌啶、吡咯烷、二氢吲哚、奎宁环和吖庚因；伯芳基胺例如苯胺、甲氧基苯胺、乙氧基苯胺、邻甲苯胺、间甲苯胺、对甲苯胺、苯二胺、联苯胺、萘基胺、邻氯苯胺、间氯苯胺和对氯苯胺；但是尤其是三乙基胺、异丙基胺和二异丙基胺。
非常令人惊奇的是，式I活性组分与一种或多种选自式2.1-2.51的活性组分的组合对欲控制杂草的作用超过了一般所预计的加和作用，因此扩大了单独活性组分的作用范围，尤其是在下列两个方面：首先，减小了单独的式2.1-2.51化合物的施用量，同时保持了良好的作用水平，其次，对于单独的活性物质以低施用量不可用的情况(从农学角度来看)，本发明组合物可获得良好的杂草控制水平。该结果是杂草谱的显著拓宽，并且提高了在有用植物农作物方面的选择性，如果发生了活性组分的非故意剂量过多，这样的结果是必须的并且可取的。在保持良好控制有用植物农作物中的杂草的同时，本发明组合物还使得在继代农作物中有更大的灵活性。
本发明组合物可用于抗大量在农业上很重要的杂草，例如繁缕属、旱金莲属、地老虎属、马唐属、燕麦属、狗尾草属、芥属、毒麦属、茄属、菜豆属、稗属、藨草属、雨久花属、慈菇属、雀麦属、看麦娘属、石茅高梁、筒轴茅属、莎草属、苘麻属、黄花稔属、苍耳属、苋属、藜属、番薯属、苘蒿属、猪殃殃属、堇菜属和婆婆纳属。本发明组合物适用于农业中的所有常用施用方法，例如芽前施用、苗后施用和种子包衣。本发明组合物尤其适用于控制有用植物农作物例如禾谷类、油菜、甜菜、甘蔗、种植园农作物、稻、玉米和大豆中的杂草，以及适用于非选择性杂草控制。
“农作物”还指通过常规育种或基因工程方法使其对除草剂或除草剂类别耐受的农作物。
优选的本发明组合物包含式I化合物，其中每个R独立地为氢、C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷硫基、C1-C6烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基、C1-C6卤代烷硫基、C1-C6卤代烷基亚磺酰基、C1-C6卤代烷基磺酰基、C1-C6烷氧基羰基、C1-C6烷基羰基、C1-C6烷基氨基、二(C1-C6烷基)氨基、C1-C6烷基氨基磺酰基、二(C1-C6烷基)氨基磺酰基、-N(R1)-S-R2、-N(R3)-SO-R4、-N(R5)-SO2-R6、硝基、氰基、卤素、羟基、氨基、苄硫基、苄基亚磺酰基、苄基磺酰基、苯基、苯氧基、苯硫基、苯基亚磺酰基或苯基磺酰基；其中所述苯基自身可被下列基团单取代、二取代或三取代：C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R45、NR46R47、卤素、氰基、硝基、苯基或苄硫基，其中后面提及的苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代；
或者每个R独立地为5-10元单环或稠合二环系，所述环系可以是芳环或部分饱和环，并且可以含有1-4个选自氮、氧和硫的杂原子；其中所述环系直接与吡啶环连接，或者经由C1-C4亚烷基与吡啶环连接，并且每个环系不可以含有2个以上的氧原子，不可以含有2个以上的硫原子，所述环系自身可被下列基团单取代、二取代或三取代：C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R7、NR8R9、卤素、氰基、硝基、苯基或苄硫基，其中所述苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代，R1、R2、R3、R4、R5、R6、R7、R8、R9、R45、R46和R47如上文所定义，并且在杂环中的氮上的取代基不是卤素。
还优选的本发明组合物包含式Ia化合物作为式I化合物
其中R48是C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基、C1-C6卤代烷基、或5-10元单环或稠合二环系，所述环系可以是芳环或部分饱和环，并且可以含有1-4个选自氮、氧和硫的杂原子，其中所述环系直接与吡啶环连接，或者经由C1-C4亚烷基与吡啶环连接，并且每个环系不可以含有2个以上的氧原子，不可以含有2个以上的硫原子，所述环系自身可被下列基团单取代、二取代或三取代：C1-C6烷基、C1-C6卤代烷基、C3-C6链烯基、C3-C6卤代链烯基、C3-C6炔基、C3-C6卤代炔基、C1-C6烷氧基、C1-C6卤代烷氧基、C3-C6链烯氧基、C3-C6炔氧基、巯基、C1-C6烷硫基、C1-C6卤代烷硫基、C3-C6链烯硫基、C3-C6卤代链烯硫基、C3-C6炔硫基、C2-C5烷氧基烷硫基、C3-C5乙酰基烷硫基、C3-C6烷氧基羰基烷硫基、C2-C4氰基烷硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、氨基磺酰基、C1-C2烷基氨基磺酰基、C2-C4二烷基氨基磺酰基、C1-C3亚烷基-R7、NR8R9、卤素、氰基、硝基、苯基或苄硫基，其中所述苯基和苄硫基自身可在苯环上被C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基取代，并且在杂环中的氮上的取代基不是卤素；
R49是氢、C1-C6烷基、C1-C6卤代烷基、卤素、或苯基，所述苯基可被下列基团取代：C1-C3烷基、C1-C3卤代烷基、C1-C3烷氧基、C1-C3卤代烷氧基、卤素、氰基或硝基，
R50是C1-C6卤代烷基，并且R7、R8、R9和Q如上文所定义。
在该组化合物当中，其中R48是C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基或C1-C6卤代烷基的那些是优选的。
对于本发明组合物还优选的是，在式I中，Q是基团Q2或Q3，其中尤其是，在基团Q2中，R23是羟基，在基团Q3中，R40是羟基。在该组化合物当中，其中m是2，且一个取代基R是C1-C4烷氧基-C1-C4烷基或C1-C4烷氧基-C1-C4烷氧基-C1-C4烷基的化合物是特别重要的。
进一步优选的本发明协同混合物包含式I化合物和下列化合物作为活性组分：式2.2.a化合物
(2.2.a，aRS，1’S(-)N-(1’-甲基-2’-甲氧基乙基)-N-氯乙酰基-2-乙基-6-甲基苯胺)或式2.2.b化合物
或式2.2化合物，其中R3是乙基、R4是甲基、且R5是乙氧基甲基，或式2.2化合物，其中R3是乙基、R4是乙基、且R5是甲氧基甲基，或化合物2.3，或式2.30化合物，或式2.4化合物，或式2.13化合物，或式2.14化合物，或式2.6化合物，其中R12是氢、Z是次甲基、R13是甲基、Y是氮、R14是氟、R15是氢、且R16是氟，或者R12是甲氧基、Z是次甲基、R13是甲氧基、Y是次甲基、R14是氯、R15是甲基、且R16是氯，或式2.7化合物，其中R17是-C(O)-S-正辛基，或式2.12化合物，或式2.18化合物，或式2.19化合物，或式2.21化合物，或式2.25化合物，或式2.33化合物，或式2.45化合物，或式2.1化合物。
尤其优选的本发明协同混合物包含式I化合物和下列化合物作为活性组分：式2.2.a化合物
(2.2.a，aRS，1’S(-)N-(1’-甲基-2’-甲氧基乙基)-N-氯乙酰基-2-乙基-6-甲基苯胺)或式2.2.b化合物
或式2.2化合物，其中R3是乙基、R4是甲基、且R5是乙氧基甲基，或式2.2化合物，其中R3是乙基、R4是乙基、且R5是甲氧基甲基，或化合物2.3，或式2.30化合物。
已经发现，式I化合物与式2.2a化合物
(2.2.a，aRS，1’S(-)N-(1’-甲基-2’-甲氧基乙基)-N-氯乙酰基-2-乙基-6-甲基苯胺)的组合是特别有效的，尤其优选的式I化合物是在下文表1中列出的化合物1.001。
式I化合物可通过类似于在WO 97/46530中描述的方法制得，所述方法包括
a)在惰性有机溶剂中，在碱存在下，将式II化合物
其中R和m如式I中所定义，且X是离去基团例如卤素，与式III、IV、V或VI化合物反应
其中R20、R23、R30和R40是羟基，且其它取代基如式I所定义，以生成式VII、VIII、IX或X化合物，
然后将这些化合物异构化，例如在碱和催化量的二甲基氨基吡啶(DMAP)或氰化物源存在下异构化；或者
b)在惰性有机溶剂中，在碱和偶联剂存在下，将式XI化合物
其中R和m如式I中所定义，
与式III、IV、V或VI化合物反应，
以形成式VII、VIII、IX或X化合物，然后将所得化合物异构化，例如按照在路线a)中描述的方法异构化。
其中Q是基团Q5的式I化合物
其中Z是硫，且R36和R01如式I中所定义，
可按照类似于已知方法(例如在WO 97/43270中描述的方法)的方法制得，所述方法包括
a)在碱、二硫化碳、和式XIII烷化剂
R01-X1 (XIII)，
其中R01如式I中所定义，且X1是离去基团例如卤素或磺酸酯，存在下，将式XII化合物
其中R36、R和m如上所定义，
转化成式XIV化合物
其中Z是硫，R、R01、R36和m如上所定义，
然后任选在溶剂中，在碱存在下，用羟基胺盐酸盐将该化合物环化，以形成式Ie化合物
其中Z是硫，且R、R36、R01和m如上所定义，
然后用氧化剂例如间氯过苯甲酸(m-CPBA)将该化合物氧化。
下列反应方案1和2中更详细地描述了式I化合物的制备。
反应方案1
路线a)：
路线b)：
含有基团Q1、Q2、Q3和Q4，其中R20、R23、R30和R40是羟基的式I化合物尤其可按照上述反应方案制得。
反应方案2
为了制备其中Q是基团Q1-Q4，且R20、R23、R30和R40是羟基的式I化合物，可依据反应方案1路线a)使用式II羧酸衍生物作为原料，其中X是离去基团，例如卤素如碘、溴或尤其是氯，N-氧基邻苯二甲酰亚胺或N，O-二甲基羟基氨基或活化酯基团例如
(由二环己基碳二亚胺(DCC)和适当羧酸形成的)或
(由N-乙基-N’-(3-二甲基氨基丙基)碳二亚胺(EDC)和适当羧酸形成的)。在惰性有机溶剂例如卤代烃如二氯甲烷，腈例如乙腈，或芳烃例如甲苯中，在碱例如烷基胺如三乙胺，芳族胺例如吡啶或4-二甲基氨基吡啶(DMAP)
存在下，将这些化合物与式III、IV、V或VI二酮衍生物反应，以形成式VII、VIII、IX和X异构体烯醇醚。酯化在0℃-110℃进行。
式VII、VIII、IX和X酯衍生物异构化成式I二酮衍生物(其中R20、R23、R30和R40是羟基)可例如按照类似于EP 369 803的方法，在碱例如烷基胺如三乙胺，碳酸盐例如碳酸钾，和催化量的DMAP或氰化物源例如丙酮氰醇或氰化钾存在下来进行。
按照反应方案1、路线b)，所需的式I二酮(其中R20、R23、R30和R40是羟基)可这样获得，例如按照类似于《化学通信》(Chem.Lett.)1975，1045的方法，在惰性溶剂例如卤代烃如二氯甲烷，腈例如乙腈，或芳烃例如甲苯中，在碱例如烷基胺如三乙胺，和偶联剂例如2-氯-1-甲基-吡啶鎓碘化物存在下，用式III、IV、V或VI二酮衍生物将式XI羧酸酯化。根据所用的溶剂，酯化可在0℃-110℃进行，并且如路线a)所述，首先生成式I异构酯，并且如路线a)所述，例如在碱和催化量的DMAP，或氰化物源存在下，式I异构酯可异构化以形成式I二酮衍生物(其中R20、R23、R30和R40是羟基)。
其中Q是基团Q5的式I化合物的制备可这样进行，即按照反应方案2，例如采用类似于《合成》(Synthesis)1991，301；同前(ibid.)1988，793或《四面体》(Tetrahedron)32，3055(1976)的方法，在碱例如碳酸盐如碳酸钾，金属氢化物如氢化钠，或者以氟化钾/铝，和式III烷基化剂存在下，其中X1是离去基团如卤素例如碘、溴或尤其是氯、R25OSO2O-、CH3SO2O-或
将式XIIb-二酮衍生物与二硫化碳反应。该反应优选在溶剂例如酰胺如N，N-二甲基甲酰胺(DMF)，亚砜例如二甲亚砜(DMSO)，或腈例如乙腈中进行。在碱例如乙酸钠存在下，在溶剂例如醇如乙醇或醚例如四氢呋喃中，使用盐酸羟胺将形成的式XIV乙烯酮缩乙硫醇环化，以形成其中Z是S-的式Ie化合物。该环化反应在0℃-100℃进行。可任选按照类似于标准方法的方法，例如使用过酸如间氯过苯甲酸(m-CPBA)或过乙酸将式Ie化合物(Z＝S)氧化，以形成相应的式Ie砜和亚砜(Z＝SO-或SO2-)，其中可通过氧化剂的量来控制硫原子的氧化程度(Z＝SO-或SO2-)。
式Ie化合物的氧化(Z＝SO-或SO2-)是按照例如在H.O.House，《现代合成反应》″Modern Synthetic Reactions″W.A.Benjamin，Inc.，Menlo Park，California，1972，p.334-335和353-354中描述的方法进行的。
在反应方案1(路线a)中，其中X是离去基团例如卤素如溴、碘或尤其是氯的式II活化羧酸衍生物可按照已知的标准方法，例如在C.Ferri″Reaktionen der organischen Synthese″，Georg Thieme Verlag，Stuttgart，1978，p.461 ff中描述的方法以及如下述反应方案3所示的方法制得。
反应方案3
按照反应方案3，式II化合物(X＝离去基团)或II(X＝卤素)的制备可通过例如使用卤化剂来进行，所述卤化剂是例如亚硫酰卤如亚硫酰氯或亚硫酰溴；卤化磷或磷酰卤例如五氯化磷或三氯氧化磷或五溴化磷或磷酰溴；或草酰卤例如草酰氯，或通过使用用于形成活化酯的试剂例如N，N’-二环己基碳二亚胺(DCC)或N-乙基-N’-(3-二甲基氨基丙基)碳二亚胺(EDC)来进行。在作为卤化剂的式X化合物中，X是离去基团，例如卤素如氟、溴或碘和尤其是氯，且W1是例如PCl2、SOCl、SOBr或ClCOCO。
该方法任选在惰性有机溶剂例如脂族烃、卤代脂族烃、芳烃或卤代芳烃例如正己烷、苯、甲苯、二甲苯、二氯甲烷、1，2-二氯乙烷或氯苯中，在-20℃-该反应混合物的回流温度下、优选40-150℃温度下，在催化量的N，N-二甲基甲酰胺存在下进行。这样的反应一般是已知的，并且以关于离去基团X的多种变化形式描述于文献中。
式III、IV、V和VI化合物是已知的，并且可按照类似于在例如WO92/07837、DE 3 818 958、EP 338 992和DE 3 902 818中描述的方法制得。
在反应方案2中的式XII化合物可通过标准方法，由例如相应的式II化合物制得
其中R和m如式I中所定义，且X是离去基团例如卤素，
例如经由克菜森缩合而制得，或者通过与式XV酮基羧酸盐反应由式II化合物制得
其中R36如式I中所定义，且M+是碱金属离子(参见例如WO 96/26192)。
式II和XI化合物是已知的，并且可按照类似于在例如WO 97/46530，《杂环》(Heterocycles)，48，779(1998)，《杂环》，46，129(1997)或《四面体通信》(Tetrahedron Letters)，1749(1998)中描述的方法制得。
为了制备所有其官能团取决于(R)m定义的其它式I化合物，可使用多种已知的标准方法例如烷基化、卤化、酰化、酰胺化、肟化、氧化和还原，合适的制备方法的选择由各中间体中的取代基的性质(反应性)决定。WO97/46353中描述了这样的反应的实例。
在式I范围内的所有其它化合物可按照考虑吡啶基和Q基团的化学性质的简单方法来制得。
式I终产物可通过浓缩或将溶剂蒸发以常规方式分离，并通过在固体残余物不易溶于其中的溶剂例如醚、芳烃或氯代烃中将固体残余物重结晶或研制，通过蒸馏或使用柱色谱与合适的洗脱剂来纯化。
此外，本领域技术人员熟悉其中一些反应应当有利进行的顺序以防止可能的副反应。
当合成不能直接使得纯的异构体分离出来时，产物可呈两种或更多种异构体的混合物的形式。可按照自身已知的方法分离异构体。
制备实施例：
实施例P1：制备4-羟基-3-(2-甲基-6-三氟甲基-吡啶-3-羰基)-二环
[3.2.11]辛-3-烯-2-酮：
将6.68g(0.0305mol)2-甲基-6-三氟甲基-烟酸甲酯(按照在《杂环》，46，129(1997)中描述的方法制得的)溶解在250ml甲醇/水(3∶1混合物)中，并在22℃分批加入1.92g(0.046mol)氢氧化锂水合物。在22℃保持4小时后，将该反应混合物加到乙酸乙酯和2N盐酸中；用水将有机相洗涤3次，用硫酸钠干燥，并通过蒸发浓缩，用少量己烷研制残余物。过滤后，获得了5.69g(产率为90％)预期的2-甲基-6-三氟甲基烟酸，熔点为147-149℃。
将所得2-甲基-6-三氟甲基-烟酸(2.0g，0.0098mol)溶解在20ml草酰氯中。加入3滴二甲基甲酰胺，并将该混合物回流1小时。然后使用旋转蒸发仪将该混合物浓缩，将残余物(2-甲基-6-三氟甲基烟酰氯)置于30ml二氯甲烷中。在0℃，加入2.7ml(0.0196mol)三乙胺和0.12g(0.00098mol)二甲基氨基吡啶，然后滴加溶解在20ml二氯甲烷中的1.49g(0.0108mol)二环[3.2.1]辛-2，4-二酮。在22℃保持3小时后，通过与2N盐酸一起振摇来萃取该反应混合物。将分离的二氯甲烷相用水洗涤，然后通过与10％碳酸氢钠水溶液振摇来萃取，用硫酸钠干燥，并通过蒸发浓缩。获得了3.18g(产率为100％)2-甲基-6-三氟甲基烟酸4-氧代二环[3.2.1]辛-2-烯-2-基酯，为油状物，可不用进一步纯化直接使用。将3.02g(0.0093mol)甲基-6-三氟甲基-烟酸4-氧代二环[3.2.1]辛-2-烯-2-基酯和1.9ml(0.0136mol)三乙胺溶解在45ml乙腈中。在22℃加入0.01ml丙酮氰醇。在22℃保持18小时后，将该反应混合物倒入水与2N盐酸的混合物中，并通过与乙酸乙酯振摇来萃取。将乙酸乙酯相依次用水和盐水洗涤，用硫酸钠干燥，并通过蒸发浓缩，将残余物溶解在少量温热的丙酮中。在静置时产物结晶出来。过滤后，获得了0.99g(产率为33％)预期的4-羟基-3-(2-甲基-6-三氟甲基-吡啶-3-羰基)-二环[3.2.1]辛基-3-烯-2-酮，为白色结晶形式(m.p.75-77℃)。
实施例P2：(5-环丙基-3-甲硫基异噁唑-4-基)-(2-甲基-6-三氟甲基-吡
啶-3-基)-甲酮：
将14.8g(0.080mol)3-环丙基-3-氧代丙酸叔丁酯溶解在25mlMeOH中，加入1.93g(0.080mol)镁。滴加7ml四氯化碳，同时在冰浴中冷却，并将该反应混合物在22℃搅拌1小时以使反应完全。通过蒸发将其浓缩后，在22℃将残余物悬浮在100ml乙腈中，并滴加溶解在50ml乙腈中的16.31g(0.073mol)2-甲基-6-三氟甲基-烟酰氯(按照实施例P1中描述的方法制得的)。6小时后，将该反应混合物置于乙酸乙酯中，并用饱和碳酸氢钠溶液洗涤。将分离出的乙酸乙酯相用水洗涤，用硫酸钠干燥，并通过蒸发浓缩。将残余物溶解在160ml二氯甲烷中，并在22℃滴加10ml三氟乙酸。18小时后，将该反应混合物倒入水中，并用二氯甲烷萃取。将二氯甲烷相依次用水和盐水洗涤，用硫酸钠干燥，并通过蒸发浓缩。获得了17.3g(产率为88％)1-环丙基-3-(2-甲基-6-三氟甲基-吡啶-3-基)-丙-1，3-二酮，为油状物，可不用进一步纯化直接使用。
将所得1-环丙基-3-(2-甲基-6-三氟甲基-吡啶-3-基)-丙-1，3-二酮(15.0g，0.055mol)溶解在150ml二甲基甲酰胺中，在0℃分批加入50g以氧化铝为载体的氟化钾(Alox)(0.0055mol/g，0.276mol)。5分钟后，加入6.7g(0.088mol)二硫化碳。2小时后，滴加23.6g(0.166mol)甲基碘，并将该反应混合物在22℃加热。2小时后，过滤出Alox，将滤液倒入水中，并通过与乙酸乙酯振摇来萃取。将乙酸乙酯相依次用水和盐水洗涤，用硫酸钠干燥，并通过蒸发浓缩。通过硅胶色谱纯化残余物(洗脱剂：乙酸乙酯/己烷15/1)。获得了12.0g(产率60％)2-(二-甲硫基-亚甲基)-1-环丙基-3-(2-甲基-6-三氟甲基-吡啶-3-基)-丙-1，3-二酮，为固体。
将12.0g(0.033mol)该产物与5.4 g(0.066mol)无水乙酸钠一起悬浮在120ml乙醇中.加入4.6g(0.066mol)盐酸羟胺，并将该混合物在22℃搅拌5小时。然后再加入2.7g无水乙酸钠和2.3g盐酸羟胺。18小时后，用水将该反应混合物稀释，并用乙酸乙酯萃取。将乙酸乙酯相依次用水和盐水洗涤，用硫酸钠干燥，并通过蒸发浓缩。用少量乙酸乙酯研制，获得了9.0g(79.5％)所需产物，为白色结晶(m.p.103-104℃)。
实施例P3：(5-环丙基-3-甲基亚磺酰基异噁唑-4-基)-(2-甲基-6-三氟甲
基-吡啶-3-基)-甲酮
将1.50g(0.0043mol)(5-环丙基-3-甲硫基异噁唑-4-基)-(2-甲基-6-三氟甲基-吡啶-3-基)-甲酮溶解在30ml丙酮/水(2∶1混合物)中，并在22℃分批加入1.02g(0.0048mol)偏高碘酸钠。5小时后，使用旋转蒸发仪通过蒸发将该反应混合物浓缩。将残余物置于水和乙酸乙酯中。用硫酸钠将乙酸乙酯相干燥，并通过蒸发浓缩。通过硅胶色谱纯化残余物(洗脱剂：乙酸乙酯/己烷3/1)。获得了0.8g(51％)所需产物，为白色结晶(m.p.96-97℃)。
实施例P4：制备3-羟基-4，4-二甲基-2-(2-甲基-6-三氟甲基-吡啶-3-羰
基)-环己-2-烯酮(A2-B24)：
将6.68g(0.0305mol)2-甲基-6-三氟甲基-烟酸甲酯(按照在《杂环》，46，129(1997)中描述的方法制得的)溶解在250ml甲醇/水(3∶1混合物)中，并在22℃分批加入1.92g(0.046mol)氢氧化锂水合物。在22℃保持4小时后，将该反应混合物加到乙酸乙酯和2N盐酸中；用水将有机相洗涤3次，用硫酸钠干燥，并通过蒸发浓缩，用少量己烷研制残余物。过滤后，获得了5.69g(产率为90％)预期的2-甲基-6-三氟甲基烟酸，熔点为147-149℃。
将所得2-甲基-6-三氟甲基-烟酸(1.026g，0.005mol)溶解在20ml草酰氯中。加入3滴二甲基甲酰胺，并将该混合物回流1小时。然后用旋转蒸发仪通过蒸发将该混合物浓缩，并将残余物(2-甲基-6-三氟甲基-烟酰氯)置于100ml二氯甲烷中。在0℃加入1.6ml(0.0115mol)三乙胺和0.7g(0.005mol)4，4-二甲基-环己烷-1，3-二酮。在22℃保持2小时后，使用旋转蒸发仪除去溶剂，将剩余的残余物溶解在55ml乙腈中，为了使该中间体重排，加入0.15ml(0.0016mol)丙酮氰醇和0.79ml(0.0057mol)三乙胺。在室温搅拌4小时后，通过蒸发将该反应溶液浓缩。通过硅胶色谱纯化剩余的浆状物.将通过用甲苯、乙醇、二氧杂环己烷、三乙胺和水的混合物(100∶40∶20∶20∶5体积份)(使用所述混合物作为流动相Rf＝0.39)洗脱而获得的浅黄色粘稠油状物溶解在二氯甲烷中，并依次用75ml盐酸5％和75ml水洗涤。用硫酸钠将有机溶液干燥后，通过蒸发浓缩，获得了1.05g(63％)纯的标题化合物。
1H NMR(d6-DMSO，δppm)：1.342，s，6H：2.088，t，J 9Hz，2H：2.685，s，3H：2.982，t，J 9Hz，2H：8.030，d，J 8.1Hz，1H：8.094，d，J8.1Hz，1H。
实施例P5：制备5-甲基-5-三氟甲基-环己烷-1，3-二酮(实施例B1066)：
将0.64g钠加到40ml乙醇中，加入3.23ml乙酸甲酯和4.9g 4，4，4-三氟-3-甲基-丁-2-烯酸异丙酯，并将该混合物在沸点温度加热18小时。用稀盐酸和乙酸乙酯萃取后，通过蒸发浓缩。将保留未纯化的2-甲基-4，6-二氧代-2-三氟甲基-环己烷甲酸甲酯在9.1g氢氧化钠存在下在甲醇与水的混合物中于沸点温度酯化。然后用盐酸将该混合物酸化，并用新鲜的乙酸乙酯萃取。重结晶(乙酸乙酯)后，获得了纯的5-甲基-5-三氟甲基环己烷-1，3-二酮，熔点为150-152℃。
实施例P6：制备2-羟基-1-甲氧基-5-甲基-4-氧代环己-2-烯甲酸甲酯
(B1069)：
用35.8g甲醇钠在65ml二甲亚砜中制成30％溶液，在30-35℃用20分钟加入16.7g 3-甲基-3-丁烯-2-酮与32.4g甲氧基丙二酸二甲酯。将该混合物在35℃搅拌1小时，用盐酸酸化，然后用二氯甲烷萃取数次。将有机相用水洗涤，干燥并浓缩。通过从热的乙酸乙酯和己烷中结晶，获得了纯的2-羟基-1-甲氧基-5-甲基-4-氧代-环己-2-烯羧酸甲酯，熔点为117-117.5℃。
实施例P7：制备2-羟基-1-甲氧基-5-甲基-3-(2-甲基-6-三氟甲基-吡啶
-3-羰基)-4-氧代-环己-2-烯羧酸甲酯(A2-B1069)：
将2.23g新制的2-甲基-6-三氟甲基-烟酰氯加到2.14g2-羟基-1-甲氧基-5-甲基-4-氧代-环己-2-烯甲酸甲酯和2.02g三乙胺在30ml乙腈内的混合物中。约30分钟后，加入0.065g氰化钾，并将该混合物搅拌18小时。然后在pH2用水和乙酸乙酯萃取，用硫酸镁干燥，并通过蒸发浓缩。经由硅胶过滤(流动相：乙酸乙酯/甲醇/三乙胺85∶10∶5)，获得了纯的2-羟基-1-甲氧基-5-甲基-3-(2-甲基-6-三氟甲基-吡啶-3-羰基)-4-氧代-环己-2-烯羧酸甲酯，为粘稠的油状物。
实施例P8：制备3-羟基-4-甲氧基-6-甲基-2-(2-甲基-6-三氟甲基-吡啶
-3-羰基)-环己-2-烯酮(A2-B1070)：
将0.586g氢氧化钾加到在二氧杂环己烷/水(5∶3)内的1.4g 2-羟基-1-甲氧基-5-甲基-3-(2-甲基-6-三氟甲基-吡啶-3-羰基)-4-氧代-环己-2-烯羧酸甲酯中，并将该混合物搅拌3小时。然后将该混合物酸化(pH3)，并用新鲜的乙酸乙酯萃取。通过类似于实施例P7的色谱法纯化粗产物，获得了3-羟基-4-甲氧基-6-甲基-2-(2-甲基-6-三氟甲基-吡啶-3-羰基)-环己-2-烯酮，为粘稠的油状物(根据1H-NMR，3种互变异构形式的混合物)。
按照类似方式，并使用在一般反应方案1和2以及其中所提及的参考文献中描述的方法，还可以制得在下表中列出的化合物。在下表中，Ph是苯基，且CC是乙炔基。
表1：式Ib化合物：
化合物 R75 R76 R77 R78 m.p.(℃)
序号
1.001 CH3 CF3 H H 75-77
1.002 CH3CH2 CF3 H H
1.003 (CH3)2CH CF3 H H 111-112
1.004 CH3(CH2)3 CF3 H H
1.005 Ph CF3 H H 油状物
1.006 CH2Br CF3 H H
1.007 CH2OCH3 CF3 H H 124-126
1.008 CH2SMe CF3 H H 油状物
1.009 CH2SO2Me CF3 H H 55-55
1.010 SCH3 CF3 H H
化合物 R75 R76 R77 R78 m.p.(℃)
序号
1.011 SOCH3 CF3 H H
1.012 SO2CH3 CF3 H H
1.013 SPh CF3 H H
1.014 SOPh CF3 H H
1.015 SO2Ph CF3 H H
1.016 CH3 CF3CF2 H H
1.017 CH3CH2 CF3CF2 H H
1.018 (CH3)2CH CF3CF2 H H
1.019 CH3(CH2)3 CF3CF2 H H
1.020 Ph CF3CF2 H H
1.021 CH2Br CF3CF2 H H
1.022 CH2OCH3 CF3CF2 H H
1.023 CH2SMe CF3CF2 H H
1.024 CH2SO2Me CF3CF2 H H
1.025 SCH3 CF3CF2 H H
1.026 SOCH3 CF3CF2 H H
1.027 SO2CH3 CF3CF2 H H
1.028 SPh CF3CF2 H H
1.029 SOPh CF3CF2 H H
1.030 SO2Ph CF3CF2 H H
1.031 CH3 CHF2 H H
1.032 CH3CH2 CHF2 H H
1.033 (CH3)2CH CHF2 H H
1.034 CH3(CH2)3 CHF2 H H
1.035 Ph CHF2 H H
1.036 CH2Br CHF2 H H
1.037 CH2OCH3 CHF2 H H
1.038 CH2SMe CHF2 H H
1.039 CH2SO2Me CHF2 H H
1.040 SCH3 CHF2 H H
1.041 SOCH3 CHF2 H H
1.042 SO2CH3 CHF2 H H
化合物 R75 R76 R77 R78 m.p.(℃)
序号
1.043 SPh CHF2 H H
1.044 SOPh CHF2 H H
1.045 SO2Ph CHF2 H H
1.046 CH3 CF3 CH3 H
1.047 CH3CH2 CF3 CH3 H
1.048 (CH3)2CH CF3 CH3 H
1.049 CH3(CH2)3 CF3 CH3 H
1.050 Ph CF3 CH3 H
1.051 CH2Br CF3 CH3 H
1.052 CH2OCH3 CF3 CH3 H
1.053 CH2SMe CF3 CH3 H
1.054 CH2SO2Me CF3 CH3 H
1.055 SCH3 CF3 CH3 H
1.056 SOCH3 CF3 CH3 H
1.057 SO2CH3 CF3 CH3 H
1.058 SPh CF3 CH3 H
1.059 SOPh CF3 CH3 H
1.060 SO2Ph CF3 CH3 H
1.061 CH3 CF3CF2 CH3 H
1.062 CH3CH2 CF3CF2 CH3 H
1.063 (CH3)2CH CF3CF2 CH3 H
1.064 CH3(CH2)3 CF3CF2 CH3 H
1.065 Ph CF3CF2 CH3 H
1.066 CH2Br CF3CF2 CH3 H
1.067 CH2OCH3 CF3CF2 CH3 H
1.068 CH2SMe CF3CF2 CH3 H
1.069 CH2SO2Me CF3CF2 CH3 H
1.070 SCH3 CF3CF2 CH3 H
1.071 SOCH3 CF3CF2 CH3 H
1.072 SO2CH3 CF3CF2 CH3 H
1.073 SPh CF3CF2 CH3 H
1.074 SOPh CF3CF2 CH3 H
化合物 R75 R76 R77 R78 m.p.(℃)
序号
1.075 SO2Ph CF3CF2 CH3 H
1.076 CH3 CHF2 CH3 H
1.077 CH3CH2 CHF2 CH3 H
1.078 (CH3)2CH CHF2 CH3 H
1.079 CH3(CH2)3 CHF2 CH3 H
1.080 Ph CHF2 CH3 H
1.081 CH2Br CHF2 CH3 H
1.082 CH2OCH3 CHF2 CH3 H
1.083 CH2SMe CHF2 CH3 H
1.084 CH2SO2Me CHF2 CH3 H
1.085 SCH3 CHF2 CH3 H
1.086 SOCH3 CHF2 CH3 H
1.087 SO2CH3 CHF2 CH3 H
1.088 SPh CHF2 CH3 H
1.089 SOPh CHF2 CH3 H
1.090 SO2Ph CHF2 CH3 H
1.091 CH3 CF3 H CH3 92-94
1.092 CH3CH2 CF3 H CH3
1.093 (CH3)2CH CF3 H CH3
1.094 CH3(CH2)3 CF3 H CH3
1.095 Ph CF3 H CH3
1.096 CH2Br CF3 H CH3
1.097 CH2OCH3 CF3 H CH3
1.098 CH2SMe CF3 H CH3
1.099 CH2SO2Me CF3 H CH3
1.100 SCH3 CF3 H CH3
1.101 SOCH3 CF3 H CH3
1.102 SO2CH3 CF3 H CH3
1.103 SPh CF3 H CH3
1.104 SOPh CF3 H CH3
1.105 SO2Ph CF3 H CH3
表2：式Ic化合物：
化合物. R75 R76 R77 R78 m.p.(℃)
序号
2.001 CH3 CF3 H H 107-109
2.002 CH3CH2 CF3 H H 油状物
2.003 (CH3)2CH CF3 H H 油状物
2.004 CH3(CH2)3 CF3 H H
2.005 Ph CF3 H H 油状物
2.006 CH2Br CF3 H H
2.007 CH2OCH3 CF3 H H
2.008 CH2SMe CF3 H H
2.009 CH2SO2Me CF3 H H
2.010 SCH3 CF3 H H
2.011 SOCH3 CF3 H H
2.012 SO2CH3 CF3 H H
2.013 SPh CF3 H H
2.014 SOPh CF3 H H
2.015 SO2Ph CF3 H H
2.016 CH3 CF3CF2 H H
2.017 CH3CH2 CF3CF2 H H
2.018 (CH3)2CH CF3CF2 H H
2.019 CH3(CH2)3 CF3CF2 H H
2.020 Ph CF3CF2 H H
2.021 CH2Br CF3CF2 H H
2.022 CH2OCH CF3CF2 H H
化合物 R75 R76 R77 R78 m.p.(℃)
序号
2.023 CH2SMe CF3CF2 H H
2.024 CH2SO2Me CF3CF2 H H
2.025 SCH3 CF3CF2 H H
2.026 SOCH3 CF3CF2 H H
2.027 SO2CH3 CF3CF2 H H
2.028 SPh CF3CF2 H H
2.029 SOPh CF3CF2 H H
2.030 SO2Ph CF3CF2 H H
2.031 CH3 CHF2 H H
2.032 CH3CH2 CHF2 H H
2.033 (CH3)2CH CHF2 H H
2.034 CH3(CH2)3 CHF2 H H
2.035 Ph CHF2 H H
2.036 CH2Br CHF2 H H
2.037 CH2OCH3 CHF2 H H
2.038 CH2SMe CHF2 H H
2.039 CH2SO2Me CHF2 H H
2.040 SCH3 CHF2 H H
2.041 SOCH3 CHF2 H H
2.042 SO2CH3 CHF2 H H
2.043 SPh CHF2 H H
2.044 SOPh CHF2 H H
2.045 SO2Ph CHF2 H H
2.046 CH3 CF3 CH3 H
2.047 CH3CH2 CF3 CH3 H
2.048 (CH3)2CH CF3 CH3 H
2.049 CH3(CH2)3 CF3 CH3 H
2.050 Ph CF3 CH3 H
2.051 CH2Br CF3 CH3 H
2.052 CH2OCH3 CF3 CH3 H
2.053 CH2SMe CF3 CH3 H
2.054 CH2SO2Me CF3 CH3 H
化合物 R75 R76 R77 R78 m.p.(℃)
序号
2.055 SCH3 CF3 CH3 H
2.056 SOCH3 CF3 CH3 H
2.057 SO2CH3 CF3 CH3 H
2.058 SPh CF3 CH3 H
2.059 SOPh CF3 CH3 H
2.060 SO2Ph CF3 CH3 H
2.061 CH3 CF3CF2 CH3 H
2.062 CH3CH2 CF3CF2 CH3 H
2.063 (CH3)2CH CF3CF2 CH3 H
2.064 CH3(CH2)3 CF3CF2 CH3 H
2.065 Ph CF3CF2 CH3 H
2.066 CH2Br CF3CF2 CH3 H
2.067 CH2OCH3 CF3CF2 CH3 H
2.068 CH2SMe CF3CF2 CH3 H
2.069 CH2SO2Me CF3CF2 CH3 H
2.070 SCH3 CF3CF2 CH3 H
2.071 SOCH3 CF3CF2 CH3 H
2.072 SO2CH3 CF3CF2 CH3 H
2.073 SPh CF3CF2 CH3 H
2.074 SOPh CF3CF2 CH3 H
2.075 SO2Ph CF3CF2 CH3 H
2.076 CH3 CHF2 CH3 H
2.077 CH3CH2 CHF2 CH3 H
2.078 (CH3)2CH CHF2 CH3 H
2.079 CH3(CH2)3 CHF2 CH3 H
2.080 Ph CHF2 CH3 H
2.081 CH2Br CHF2 CH3 H
2.082 CH2OCH3 CHF2 CH3 H
2.083 CH2SMe CHF2 CH3 H
2.084 CH2SO2Me CHF2 CH3 H
2.085 SCH3 CHF2 CH3 H
2.086 SOCH3 CHF2 CH3 H
化合物 R75 R76 R77 R78 m.p.(℃)
序号
2.087 SO2CH3 CHF2 CH3 H
2.088 SPh CHF2 CH3 H
2.089 SOPh CHF2 CH3 H
2.090 SO2Ph CHF2 CH3 H
2.091 CH3 CF3 H CH3
2.092 CH3CH2 CF3 H CH3
2.093 (CH3)2CH CF3 H CH3
2.094 CH3(CH2)3 CF3 H CH3
2.095 Ph CF3 H CH3
2.096 CH2Br CF3 H CH3
2.097 CH2OCH3 CF3 H CH3
2.098 CH2SMe CF3 H CH3
2.099 CH2SO2Me CF3 H CH3
2.100 SCH3 CF3 H CH3
2.101 SOCH3 CF3 H CH3
2.102 SO2CH3 CF3 H CH3
2.103 SPh CF3 H CH3
2.104 SOPh CF3 H CH3
2.105 SO2Ph CF3 H CH3
表3：式Id化合物：
化合物. R75 R76 R77 R78 m.p.(℃)
序号
化合物 R75 R76 R77 R78 m.p.(℃)
序号
3.001 CH3 CF3 H H
3.002 CH3CH2 CF3 H H
3.003 (CH3)2CH CF3 H H
3.004 CH3(CH2)3 CF3 H H
3.005 Ph CF3 H H
3.006 CH2Br CF3 H H
3.007 CH2OCH3 CF3 H H
3.008 CH2SMe CF3 H H
3.009 CH2SO2Me CF3 H H
3.010 SCH3 CF3 H H
3.011 SOCH3 CF3 H H
3.012 SO2CH3 CF3 H H
3.013 SPh CF3 H H
3.014 SOPh CF3 H H
3.015 SO2Ph CF3 H H
3.016 CH3 CF3CF2 H H
3.017 CH3CH2 CF3CF2 H H
3.018 (CH3)2CH CF3CF2 H H
3.019 CH3(CH2)3 CF3CF2 H H
3.020 Ph CF3CF2 H H
3.021 CH2Br CF3CF2 H H
3.022 CH2OCH3 CF3CF2 H H
3.023 CH2SMe CF3CF2 H H
3.024 CH2SO2Me CF3CF2 H H
3.025 SCH3 CF3CF2 H H
3.026 SOCH3 CF3CF2 H H
3.027 SO2CH3 CF3CF2 H H
3.028 SPh CF3CF2 H H
3.029 SOPh CF3CF2 H H
3.030 SO2Ph CF3CF2 H H
3.031 CH3 CHF2 H H
化合物 R75 R76 R77 R78 m.p.(℃)
序号
3.032 CH3CH2 CHF2 H H
3.033 (CH3)2CH CHF2 H H
3.034 CH3(CH2)3 CHF2 H H
3.035 Ph CHF2 H H
3.036 CH2Br CHF2 H H
3.037 CH2OCH3 CHF2 H H
3.038 CH2SMe CHF2 H H
3.039 CH2SO2Me CHF2 H H
3.040 SCH3 CHF2 H H
3.041 SOCH3 CHF2 H H
3.042 SO2CH3 CHF2 H H
3.043 SPh CHF2 H H
3.044 SOPh CHF2 H H
3.045 SO2Ph CHF2 H H
3.046 CH3 CF3 CH3 H
3.047 CH3CH2 CF3 CH3 H
3.048 (CH3)2CH CF3 CH3 H
3.049 CH3(CH2)3 CF3 CH3 H
3.050 Ph CF3 CH3 H
3.051 CH2Br CF3 CH3 H
3.052 CH2OCH3 CF3 CH3 H
3.053 CH2SMe CF3 CH3 H
3.054 CH2SO2Me CF3 CH3 H
3.055 SCH3 CF3 CH3 H
3.056 SOCH3 CF3 CH3 H
3.057 SO2CH3 CF3 CH3 H
3.058 SPh CF3 CH3 H
3.059 SOPh CF3 CH3 H
3.060 SO2Ph CF3 CH3 H
3.061 CH3 CF3CF2 CH3 H
3.062 CH3CH2 CF3CF2 CH3 H
3.063 (CH3)2CH CF3CF2 CH3 H
化合物 R75 R76 R77 R78 m.p.(℃)
序号
3.064 CH3(CH2)3 CF3CF2 CH3 H
3.065 Ph CF3CF2 CH3 H
3.066 CH2Br CF3CF2 CH3 H
3.067 CH2OCH3 CF3CF2 CH3 H
3.068 CH2SMe CF3CF2 CH3 H
3.069 CH2SO2Me CF3CF2 CH3 H
3.070 SCH3 CF3CF2 CH3 H
3.071 SOCH3 CF3CF2 CH3 H
3.072 SO2CH3 CF3CF2 CH3 H
3.073 SPh CF3CF2 CH3 H
3.074 SOPh CF3CF2 CH3 H
3.075 SO2Ph CF3CF2 CH3 H
3.076 CH3 CHF2 CH3 H
3.077 CH3CH2 CHF2 CH3 H
3.078 (CH3)2CH CHF2 CH3 H
3.079 CH3(CH2)3 CHF2 CH3 H
3.080 Ph CHF2 CH3 H
3.081 CH2Br CHF2 CH3 H
3.082 CH2OCH3 CHF2 CH3 H
3.083 CH2SMe CHF2 CH3 H
3.084 CH2SO2Me CHF2 CH3 H
3.085 SCH3 CHF2 CH3 H
3.086 SOCH3 CHF2 CH3 H
3.087 SO2CH3 CHF2 CH3 H
3.088 SPh CHF2 CH3 H
3.089 SOPh CHF2 CH3 H
3.090 SO2Ph CHF2 CH3 H
3.091 CH3 CF3 H CH3
3.092 CH3CH2 CF3 H CH3
3.093 (CH3)2CH CF3 H CH3
3.094 CH3(CH2)3 CF3 H CH3
3.095 Ph CF3 H CH3
化合物 R75 R76 R77 R78 m.p.(℃)
序号
3.096 CH2Br CF3 H CH3
3.097 CH2OCH3 CF3 H CH3
3.098 CH2SMe CF3 H CH3
3.099 CH2SO2Me CF3 H CH3
3.100 SCH3 CF3 H CH3
3.101 SOCH3 CF3 H CH3
3.102 SO2CH3 CF3 H CH3
3.103 SPh CF3 H CH3
3.104 SOPh CF3 H CH3
3.105 SO2Ph CF3 H CH3
表4：式Ie化合物：
化合物 R75 R76 R77 R78 Z m.p.(℃)
序号
4.001 CH3 CF3 H H S 103-104
4.002 CH3CH2 CF3 H H S
4.003 (CH3)2CH CF3 H H S
4.004 CH3(CH2)3 CF3 H H S
4.005 Ph CF3 H H S
4.006 CH2Br CF3 H H S
4.007 CH2OCH3 CF3 H H S
4.008 CH2SMe CF3 H H S
化合物 R75 R76 R77 R78 Z m.p.(℃)
序号
4.009 CH2SO2Me CF3 H H S
4.010 SCH3 CF3 H H S
4.011 SOCH3 CF3 H H S
4.012 SO2CH3 CF3 H H S
4.013 SPh CF3 H H S
4.014 SOPh CF3 H H S
4.015 SO2Ph CF3 H H S
4.016 CH3 CF3CF2 H H S
4.017 CH3CH2 CF3CF2 H H S
4.018 (CH3)2CH CF3CF2 H H S
4.019 CH3(CH2)3 CF3CF2 H H S
4.020 Ph CF3CF2 H H S
4.021 CH2Br CF3CF2 H H S
4.022 CH2OCH3 CF3CF2 H H S
4.023 CH2SMe CF3CF2 H H S
4.024 CH2SO2Me CF3CF2 H H S
4.025 SCH3 CF3CF2 H H S
4.026 SOCH3 CF3CF2 H H S
4.027 SO2CH3 CF3CF2 H H S
4.028 SPh CF3CF2 H H S
4.029 SOPh CF3CF2 H H S
4.030 SO2Ph CF3CF2 H H S
4.031 CH3 CHF2 H H S
4.032 CH3CH2 CHF2 H H S
4.033 (CH3)2CH CHF2 H H S
4.034 CH3(CH2)3 CHF2 H H S
4.035 Ph CHF2 H H S
4.036 CH2Br CHF2 H H S
4.037 CH2OCH3 CHF2 H H S
4.038 CH2SMe CHF2 H H S
4.039 CH2SO2Me CHF2 H H S
4.040 SCH3 CHF2 H H S
化合物 R75 R76 R77 R78 Z m.p.(℃)
序号
4.041 SOCH3 CHF2 H H S
4.042 SO2CH3 CHF2 H H S
4.043 SPh CHF2 H H S
4.044 SOPh CHF2 H H S
4.045 SO2Ph CHF2 H H S
4.046 CH3 CF3 CH3 H S
4.047 CH3CH2 CF3 CH3 H S
4.048 (CH3)2CH CF3 CH3 H S
4.049 CH3(CH2)3 CF3 CH3 H S
4.050 Ph CF3 CH3 H S
4.051 CH2Br CF3 CH3 H S
4.052 CH2OCH3 CF3 CH3 H S
4.053 CH2SMe CF3 CH3 H S
4.054 CH2SO2Me CF3 CH3 H S
4.055 SCH3 CF3 CH3 H S
4.056 SOCH3 CF3 CH3 H S
4.057 SO2CH3 CF3 CH3 H S
4.058 SPh CF3 CH3 H S
4.059 SOPh CF3 CH3 H S
4.060 SO2Ph CF3 CH3 H S
4.061 CH3 CF3CF2 CH3 H S
4.062 CH3CH2 CF3CF2 CH3 H S
4.063 (CH3)2CH CF3CF2 CH3 H S
4.064 CH3(CH2)3 CF3CF2 CH3 H S
4.065 Ph CF3CF2 CH3 H S
4.066 CH2Br CF3CF2 CH3 H S
4.067 CH2OCH3 CF3CF2 CH3 H S
4.068 CH2SMe CF3CF2 CH3 H S
4.069 CH2SO2Me CF3CF2 CH3 H S
4.070 SCH3 CF3CF2 CH3 H S
4.071 SOCH3 CF3CF2 CH3 H S
4.072 SO2CH3 CF3CF2 CH3 H S
化合物 R75 R76 R77 R78 Z m.p.(℃)
序号
4.073 SPh CF3CF2 CH3 H S
4.074 SOPh CF3CF2 CH3 H S
4.075 SO2Ph CF3CF2 CH3 H S
4.076 CH3 CHF2 CH3 H S
4.077 CH3CH2 CHF2 CH3 H S
4.078 (CH3)2CH CHF2 CH3 H S
4.079 CH3(CH2)3 CHF2 CH3 H S
4.080 Ph CHF2 CH3 H S
4.081 CH2Br CHF2 CH3 H S
4.082 CH2OCH3 CHF2 CH3 H S
4.083 CH2SMe CHF2 CH3 H S
4.084 CH2SO2Me CHF2 CH3 H S
4.085 SCH3 CHF2 CH3 H S
4.086 SOCH3 CHF2 CH3 H S
4.087 SO2CH3 CHF2 CH3 H S
4.088 SPh CHF2 CH3 H S
4.089 SOPh CHF2 CH3 H S
4.090 SO2Ph CHF2 CH3 H S
4.091 CH3 CF3 H CH3 S
4.092 CH3CH2 CF3 H CH3 S
4.093 (CH3)2CH CF3 H CH3 S
4.094 CH3(CH2)3 CF3 H CH3 S
4.095 Ph CF3 H CH3 S
4.096 CH2Br CF3 H CH3 S
4.097 CH2OCH3 CF3 H CH3 S
4.098 CH2SMe CF3 H CH3 S
4.099 CH2SO2Me CF3 H CH3 S
4.100 SCH3 CF3 H CH3 S
4.101 SOCH3 CF3 H CH3 S
4.102 SO2CH3 CF3 H CH3 S
4.103 SPh CF3 H CH3 S
4.104 SOPh CF3 H CH3 S
化合物. R75 R76 R77 R78 Z m.p.(℃)
序号
4.105 SO2Ph CF3 H CH3 S
4.106 CH3 CF3 H H SO 96-97
4.107 CH3CH2 CF3 H H SO
4.108 (CH3)2CH CF3 H H SO
4.109 CH3(CH2)3 CF3 H H SO
4.110 Ph CF3 H H SO
4.111 CH2Br CF3 H H SO
4.112 CH2OCH3 CF3 H H SO
4.113 CH2SMe CF3 H H SO
4.114 CH2SO2Me CF3 H H SO
4.115 SCH3 CF3 H H SO
4.116 SOCH3 CF3 H H SO
4.117 SO2CH3 CF3 H H SO
4.118 SPh CF3 H H SO
4.119 SOPh CF3 H H SO
4.120 SO2Ph CF3 H H SO
4.121 CH3 CF3CF2 H H SO
4.122 CH3CH2 CF3CF2 H H SO
4.123 (CH3)2CH CF3CF2 H H SO
4.124 CH3(CH2)3 CF3CF2 H H SO
4.125 Ph CF3CF2 H H SO
4.126 CH2Br CF3CF2 H H SO
4.127 CH2OCH3 CF3CF2 H H SO
4.128 CH2SMe CF3CF2 H H SO
4.129 CH2SO2Me CF3CF2 H H SO
4.130 SCH3 CF3CF2 H H SO
4.131 SOCH3 CF3CF2 H H SO
4.132 SO2CH3 CF3CF2 H H SO
4.133 SPh CF3CF2 H H SO
4.134 SOPh CF3CF2 H H SO
4.135 SO2Ph CF3CF2 H H SO
4.136 CH3 CHF2 H H SO
化合物. R75 R76 R77 R78 Z m.p.(℃)
序号
4.137 CH3CH2 CHF2 H H SO
4.138 (CH3)2CH CHF2 H H SO
4.139 CH3(CH2)3 CHF2 H H SO
4.140 Ph CHF2 H H SO
4.141 CH2Br CHF2 H H SO
4.142 CH2OCH3 CHF2 H H SO
4.143 CH2SMe CHF2 H H SO
4.144 CH2SO2Me CHF2 H H SO
4.145 SCH3 CHF2 H H SO
4.146 SOCH3 CHF2 H H SO
4.147 SO2CH3 CHF2 H H SO
4.148 SPh CHF2 H H SO
4.149 SOPh CHF2 H H SO
4.150 SO2Ph CHF2 H H SO
4.151 CH3 CF3 CH3 H SO
4.152 CH3CH2 CF3 CH3 H SO
4.153 (CH3)2CH CF3 CH3 H SO
4.154 CH3(CH2)3 CF3 CH3 H SO
4.155 Ph CF3 CH3 H SO
4.156 CH2Br CF3 CH3 H SO
4.157 CH2OCH3 CF3 CH3 H SO
4.158 CH2SMe CF3 CH3 H SO
4.159 CH2SO2Me CF3 CH3 H SO
4.160 SCH3 CF3 CH3 H SO
4.161 SOCH3 CF3 CH3 H SO
4.162 SO2CH3 CF3 CH3 H SO
4.163 SPh CF3 CH3 H SO
4.164 SOPh CF3 CH3 H SO
4.165 SO2Ph CF3 CH3 H SO
4.166 CH3 CF3CF2 CH3 H SO
4.167 CH3CH2 CF3CF2 CH3 H SO
4.168 (CH3)2CH CF3CF2 CH3 H SO
化合物 R75 R76 R77 R78 Z m.p.(℃)
序号
4.169 CH3(CH2)3 CF3CF2 CH3 H SO
4.170 Ph CF3CF2 CH3 H SO
4.171 CH2Br CF3CF2 CH3 H SO
4.172 CH2OCH3 CF3CF2 CH3 H SO
4.173 CH2SMe CF3CF2 CH3 H SO
4.174 CH2SO2Me CF3CF2 CH3 H SO
4.175 SCH3 CF3CF2 CH3 H SO
4.176 SOCH3 CF3CF2 CH3 H SO
4.177 SO2CH3 CF3CF2 CH3 H SO
4.178 SPh CF3CF2 CH3 H SO
4.179 SOPh CF3CF2 CH3 H SO
4.180 SO2Ph CF3CF2 CH3 H SO
4.181 CH3 CHF2 CH3 H SO
4.182 CH3CH2 CHF2 CH3 H SO
4.183 (CH3)2CH CHF2 CH3 H SO
4.184 CH3(CH2)3 CHF2 CH3 H SO
4.185 Ph CHF2 CH3 H SO
4.186 CH2Br CHF2 CH3 H SO
4.187 CH2OCH3 CHF2 CH3 H SO
4.188 CH2SMe CHF2 CH3 H SO
4.189 CH2SO2Me CHF2 CH3 H SO
4.190 SCH3 CHF2 CH3 H SO
4.191 SOCH3 CHF2 CH3 H SO
4.192 SO2CH3 CHF2 CH3 H SO
4.193 SPh CHF2 CH3 H SO
4.194 SOPh CHF2 CH3 H SO
4.195 SO2Ph CHF2 CH3 H SO
4.196 CH3 CF3 H CH3 SO
4.197 CH3CH2 CF3 H CH3 SO
4.198 (CH3)2CH CF3 H CH3 SO
4.199 CH3(CH2)3 CF3 H CH3 SO
4.200 Ph CF3 H CH3 SO
化合物 R75 R76 R77 R78 Z m.p.(℃)
序号
4.201 CH2Br CF3 H CH3 SO
4.202 CH2OCH3 CF3 H CH3 SO
4.203 CH2SMe CF3 H CH3 SO
4.204 CH2SO2Me CF3 H CH3 SO
4.205 SCH3 CF3 H CH3 SO
4.206 SOCH3 CF3 H CH3 SO
4.207 SO2CH3 CF3 H CH3 SO
4.208 SPh CF3 H CH3 SO
4.209 SOPh CF3 H CH3 SO
4.210 SO2Ph CF3 H CH3 SO
4.211 CH3 CF3 H H SO2 无定形
4.212 CH3CH2 CF3 H H SO2
4.213 (CH3)2CH CF3 H H SO2
4.214 CH3(CH2)3 CF3 H H SO2
4.215 Ph CF3 H H SO2
4.216 CH2Br CF3 H H SO2
4.217 CH2OCH3 CF3 H H SO2
4.218 CH2SMe CF3 H H SO2
4.219 CH2SO2Me CF3 H H SO2
4.220 SCH3 CF3 H H SO2
4.221 SOCH3 CF3 H H SO2
4.222 SO2CH3 CF3 H H SO2
4.223 SPh CF3 H H SO2
4.224 SOPh CF3 H H SO2
4.225 SO2Ph CF3 H H SO2
4.226 CH3 CF3CF2 H H SO2
4.227 CH3CH2 CF3CF2 H H SO2
4.228 (CH3)2CH CF3CF2 H H SO2
4.229 CH3(CH2)3 CF3CF2 H H SO2
4.230 Ph CF3CF2 H H SO2
4.231 CH2Br CF3CF2 H H SO2
化合物 R75 R76 R77 R78 Z m.p.(℃)
序号
4.232 CH2OCH3 CF3CF2 H H SO2
4.233 CH2SMe CF3CF2 H H SO2
4.234 CH2SO2Me CF3CF2 H H SO2
4.235 SCH3 CF3CF2 H H SO2
4.236 SOCH3 CF3CF2 H H SO2
4.237 SO2CH3 CF3CF2 H H SO2
4.238 SPh CF3CF2 H H SO2
4.239 SOPh CF3CF2 H H SO2
4.240 SO2Ph CF3CF2 H H SO2
4.241 CH3 CHF2 H H SO2
4.242 CH3CH2 CHF2 H H SO2
4.243 (CH3)2CH CHF2 H H SO2
4.244 CH3(CH2)3 CHF2 H H SO2
4.245 Ph CHF2 H H SO2
4.246 CH2Br CHF2 H H SO2
4.247 CH2OCH3 CHF2 H H SO2
4.248 CH2SMe CHF2 H H SO2
4.249 CH2SO2Me CHF2 H H SO2
4.250 SCH3 CHF2 H H SO2
4.251 SOCH3 CHF2 H H SO2
4.252 SO2CH3 CHF2 H H SO2
4.253 SPh CHF2 H H SO2
4.254 SOPh CHF2 H H SO2
4.255 SO2Ph CHF2 H H SO2
4.256 CH3 CF3 CH3 H SO2
4.257 CH3CH2 CF3 CH3 H SO2
4.258 (CH3)2CH CF3 CH3 H SO2
4.259 CH3(CH2)3 CF3 CH3 H SO2
4.260 Ph CF3 CH3 H SO2
4.261 CH2Br CF3 CH3 H SO2
4.262 CH2OCH3 CF3 CH3 H SO2
4.263 CH2SMe CF3 CH3 H SO2
化合物 R75 R76 R77 R78 Z m.p.(℃)
序号
4.264 CH2SO2Me CF3 CH3 H SO2
4.265 SCH3 CF3 CH3 H SO2
4.266 SOCH3 CF3 CH3 H SO2
4.267 SO2CH3 CF3 CH3 H SO2
4.268 SPh CF3 CH3 H SO2
4.269 SOPh CF3 CH3 H SO2
4.270 SO2Ph CF3 CH3 H SO2
4.271 CH3 CF3CF2 CH3 H SO2
4.272 CH3CH2 CF3CF2 CH3 H SO2
4.273 (CH3)2CH CF3CF2 CH3 H SO2
4.274 CH3(CH2)3 CF3CF2 CH3 H SO2
4.275 Ph CF3CF2 CH3 H SO2
4.276 CH2Br CF3CF2 CH3 H SO2
4.277 CH2OCH3 CF3CF2 CH3 H SO2
4.278 CH2SMe CF3CF2 CH3 H SO2
4.279 CH2SO2Me CF3CF2 CH3 H SO2
4.280 SCH3 CF3CF2 CH3 H SO2
4.281 SOCH3 CF3CF2 CH3 H SO2
4.282 SO2CH3 CF3CF2 CH3 H SO2
4.283 SPh CF3CF2 CH3 H SO2
4.284 SOPh CF3CF2 CH3 H SO2
4.285 SO2Ph CF3CF2 CH3 H SO2
4.286 CH3 CHF2 CH3 H SO2
4.287 CH3CH2 CHF2 CH3 H SO2
4.288 (CH3)2CH CHF2 CH3 H SO2
4.289 CH3(CH2)3 CHF2 CH3 H SO2
4.290 Ph CHF2 CH3 H SO2
4.291 CH2Br CHF2 CH3 H SO2
4.292 CH2OCH3 CHF2 CH3 H SO2
4.293 CH2SMe CHF2 CH3 H SO2
4.294 CH2SO2Me CHF2 CH3 H SO2
4.295 SCH3 CHF2 CH3 H SO2
化合物 R75 R76 R77 R78 Z m.p.(℃)
序号
4.296 SOCH3 CHF2 CH3 H SO2
4.297 SO2CH3 CHF2 CH3 H SO2
4.298 SPh CHF2 CH3 H SO2
4.299 SOPh CHF2 CH3 H SO2
4.300 SO2Ph CHF2 CH3 H SO2
4.301 CH3 CF3 H CH3 SO2
4.302 CH3CH2 CF3 H CH3 SO2
4.303 (CH3)2CH CF3 H CH3 SO2
4.304 CH3(CH2)3 CF3 H CH3 SO2
4.305 Ph CF3 H CH3 SO2
4.306 CH2Br CF3 H CH3 SO2
4.307 CH2OCH3 CF3 H CH3 SO2
4.308 CH2SMe CF3 H CH3 SO2
4.309 CH2SO2Me CF3 H CH3 SO2
4.310 SCH3 CF3 H CH3 SO2
4.311 SOCH3 CF3 H CH3 SO2
4.312 SO2CH3 CF3 H CH3 SO2
4.313 SPh CF3 H CH3 SO2
4.314 SOPh CF3 H CH3 SO2
4.315 SO2Ph CF3 H CH3 SO2
表5：式XVI化合物：
化合物 R79 R80 R81 R82
序号
A1 H H H CF3
化合物. R79 R80 R81 R82
序号
A2 CH3 H H CF3
A3 CH3CH2 H H CF3
A4 (CH3)2CH H H CF3
A5 (CH3)3C H H CF3
A6 环丙基 H H CF3
A7 CH3(CH2)2 H H CF3
A8 CH3OCH2 H H CF3
A9 CH3O(CH2)2 H H CF3
A10 Ph H H CF3
A11 PhO H H CF3
A12 PhS H H CF3
A13 PhSO H H CF3
A14 PhSO2 H H CF3
A15 CH3S H H CF3
A16 CH3SO H H CF3
A17 CF3 H H CF3
A18 F2CH H H CF3
A19 HCC H H CF3
A20 CH3CC H H CF3
A21 CH2＝CH H H CF3
A22 CH2＝CHCH2 H H CF3
A23 CH3SO2N(CH3) H H CF3
A24 (CH3)2N H H CF3
A25 (CH3)2NSO2 H H CF3
A26 ClCH2 H H CF3
A27 CH3SCH2 H H CF3
A28 CH3SOCH2 H H CF3
A29 CH3SO2CH2 H H CF3
A30 [1，2，4]-三唑-1-基-甲基 H H CF3
A31 CH3 CF3 H CH3
A32 CH3 CH3 H CF3
A33 H H H CF3CF2
化合物 R79 R80 R81 R82
序号
A34 CH3 H H CF3CF2
A35 CH3CH2 H H CF3CF2
A36 环丙基 H H CF3CF2
A37 (CH3)3C H H CF3CF2
A38 (CH3)2CH H H CF3CF2
A39 CH3(CH2)2 H H CF3CF2
A40 CH3OCH2 H H CF3CF2
A41 CH3O(CH2)2 H H CF3CF2
A42 Ph H H CF3CF2
A43 PhO H H CF3CF2
A44 PhS H H CF3CF2
A45 PhSO H H CF3CF2
A46 PhSO2 H H CF3CF2
A47 CH3S H H CF3CF2
A48 CH3SO H H CF3CF2
A49 CF3 H H CF3CF2
A50 F2CH H H CF3CF2
A51 HCC H H CF3CF2
A52 CH3CC H H CF3CF2
A53 CH2＝CH H H CF3CF2
A54 CH2＝CHCH2 H H CF3CF2
A55 CH3SO2N(CH3) H H CF3CF2
A56 (CH3)2N H H CF3CF2
A57 (CH3)2NSO2 H H CF3CF2
A58 ClCH2 H H CF3CF2
A59 CH3SCH2 H H CF3CF2
A60 CH3SOCH2 H H CF3CF2
A6 1 CH3SO2CH2 H H CF3CF2
A62 [1，2，4]-三唑-1-基-甲基 H H CF3CF2
A63 H H H CF3CF2CF2
A64 CH3 H H CF3CF2CF2
A65 CH3CH2 H H CF3CF2CF2
化合物.R79 R80 R81 R82
序号
A66 环丙基 H H CF3CF2CF2
A67 (CH3)3C H H CF3CF2CF2
A68 (CH3)2CH H H CF3CF2CF2
A69 CH3(CH2)2 H H CF3CF2CF2
A70 CH3OCH2 H H CF3CF2CF2
A71 CH3O(CH2)2 H H CF3CF2CF2
A72 Ph H H CF3CF2CF2
A73 PhO H H CF3CF2CF2
A74 PhS H H CF3CF2CF2
A75 PhSO H H CF3CF2CF2
A76 PhSO2 H H CF3CF2CF2
A77 CH3S H H CF3CF2CF2
A78 CH3SO H H CF3CF2CF2
A79 CF3 H H CF3CF2CF2
A80 F2CH H H CF3CF2CF2
A81 HCC H H CF3CF2CF2
A82 CH3CC H H CF3CF2CF2
A83 CH2＝CH H H CF3CF2CF2
A84 CH2＝CHCH2 H H CF3CF2CF2
A85 CH3SO2N(CH3) H H CF3CF2CF2
A86 (CH3)2N H H CF3CF2CF2
A87 (CH3)2NSO2 H H CF3CF2CF2
A88 ClCH2 H H CF3CF2CF2
A89 CH3SCH2 H H CF3CF2CF2
A90 CH3SOCH2 H H CF3CF2CF2
A91 CH3SO2CH2 H H CF3CF2CF2
A92 [1，2，4]-三唑-1-基-甲基 H H CF3CF2CF2
A93 H H H CF2Cl
A94 CH3 H H CF2Cl
A95 CH3CH2 H H CF2Cl
A96 环丙基 H H CF2Cl
A97 (CH3)3C H H CF2Cl
化合物 R79 R80 R81 R82
序号
A98 (CH3)2CH H H CF2Cl
A99 CH3(CH2)2 H H CF2Cl
A100 CH3OCH2 H H CF2Cl
A101 CH3O(CH2)2 H H CF2Cl
A102 Ph H H CF2Cl
A103 PhO H H CF2Cl
A104 PhS H H CF2Cl
A105 PhSO H H CF2Cl
A106 PhSO2 H H CF2Cl
A107 CH3S H H CF2Cl
A108 CH3SO H H CF2Cl
A109 CF3 H H CF2Cl
A110 F2CH H H CF2Cl
A111 HCC H H CF2Cl
A112 CH3CC H H CF2Cl
A113 CH2＝CH H H CF2Cl
A114 CH2＝CHCH2 H H CF2Cl
A115 CH3SO2N(CH3) H H CF2Cl
A116 (CH3)2N H H CF2Cl
A117 (CH3)2NSO2 H H CF2Cl
A118 ClCH2 H H CF2Cl
A119 CH3SCH2 H H CF2Cl
A120 CH3SOCH2 H H CF2Cl
A121 CH3SO2CH2 H H CF2Cl
A122 [1，2，4]-三唑-1-基-甲基 H H CF2Cl
A123 H H H CHF2
A124 CH3 H H CHF2
A125 CH3CH2 H H CHF2
A126 环丙基 H H CHF2
A127 (CH3)3C H H CHF2
A128 (CH3)2CH H H CHF2
A129 CH3(CH2)2 H H CHF2
化合物 R79 R80 R81 R82
序号
A130 CH3OCH2 H H CHF2
A131 CH3O(CH2)2 H H CHF2
A132 Ph H H CHF2
A133 PhO H H CHF2
A134 PhS H H CHF2
A135 PhSO H H CHF2
A136 PhSO2 H H CHF2
A137 CH3S H H CHF2
A138 CH3SO H H CHF2
A139 CF3 H H CHF2
A140 F2CH H H CHF2
A141 HCC H H CHF2
A142 CH3CC H H CHF2
A143 CH2＝CH H H CHF2
A144 CH2＝CHCH2 H H CHF2
A145 CH3SO2N(CH3) H H CHF2
A146 (CH3)2N H H CHF2
A147 (CH3)2NSO2 H H CHF2
A148 ClCH2 H H CHF2
A149 CH3SCH2 H H CHF2
A150 CH3SOCH2 H H CHF2
A151 CH3SO2CH2 H H CHF2
A152 [1，2，4]-三唑-1-基-甲基 H H CHF2
A153 H H H CCl3
A154 CH3 H H CCl3
A155 CH3CH2 H H CCl3
A156 环丙基 H H CCl3
A157 (CH3)3C H H CCl3
A158 (CH3)2CH H H CCl3
A159 CH3(CH2)2 H H CCl3
A160 CH3OCH2 H H CCl3
A161 CH3O(CH2)2 H H CCl3
化合物 R79 R80 R81 R82
序号
A162 Ph H H CCl3
A163 PhO H H CCl3
A164 PhS H H CCl3
A165 PhSO H H CCl3
A166 PhSO2 H H CCl3
A167 CH3S H H CCl3
A168 CH3SO H H CCl3
A169 CF3 H H CCl3
A170 F2CH H H CCl3
A171 HCC H H CCl3
A172 CH3CC H H CCl3
A173 CH2＝CH H H CCl3
A174 CH2＝CHCH2 H H CCl3
A175 CH3SO2N(CH3) H H CCl3
A176 (CH3)2N H H CCl3
A177 (CH3)2NSO2 H H CCl3
A178 ClCH2 H H CCl3
A179 CH3SCH2 H H CCl3
A180 CH3SOCH2 H H CCl3
A181 CH3SO2CH2 H H CCl3
A182 [1，2，4]-三唑-1-基-甲基 H H CCl3
A183 H H CH3 CF3
A184 CH3 H CH3 CF3
A185 CH3CH2 H CH3 CF3
A186 环丙基 H CH3 CF3
A187 (CH3)3C H CH3 CF3
A188 (CH3)2CH H CH3 CF3
A189 CH3(CH2)2 H CH3 CF3
A190 CH3OCH2 H CH3 CF3
A191 CH3O(CH2)2 H CH3 CF3
A192 Ph H CH3 CF3
A193 PhO H CH3 CF3
化合物 R79 R80 R81 R82
序号
A194 PhS H CH3 CF3
A195 PhSO H CH3 CF3
A196 PhSO2 H CH3 CF3
A197 CH3S H CH3 CF3
A198 CH3SO H CH3 CF3
A199 CF3 H CH3 CF3
A200 F2CH H CH3 CF3
A201 HCC H CH3 CF3
A202 CH3CC H CH3 CF3
A203 CH2＝CH H CH3 CF3
A204 CH2＝CHCH2 H CH3 CF3
A205 CH3SO2N(CH3) H CH3 CF3
A206 (CH3)2N H CH3 CF3
A207 (CH3)2NSO2 H CH3 CF3
A208 ClCH2 H CH3 CF3
A209 CH3SCH2 H CH3 CF3
A210 CH3SOCH2 H CH3 CF3
A211 CH3SO2CH2 H CH3 CF3
A212 H H CH3 CF3CF2
A213 CH3 H CH3 CF3CF2
A214 CH3CH2 H CH3 CF3CF2
A215 环丙基 H CH3 CF3CF2
A216 (CH3)3C H CH3 CF3CF2
A217 (CH3)2CH H CH3 CF3CF2
A218 CH3(CH2)2 H CH3 CF3CF2
A219 CH3OCH2 H CH3 CF3CF2
A220 CH3O(CH2)2 H CH3 CF3CF2
A221 Ph H CH3 CF3CF2
A222 PhO H CH3 CF3CF2
A223 PhS H CH3 CF3CF2
A224 PhSO H CH3 CF3CF2
A225 PhSO2 H CH3 CF3CF2
化合物 R79 R80 R81 R82
序号
A226 CH3S H CH3 CF3CF2
A227 CH3SO H CH3 CF3CF2
A228 CF3 H CH3 CF3CF2
A229 F2CH H CH3 CF3CF2
A230 HCC H CH3 CF3CF2
A231 CH3CC H CH3 CF3CF2
A232 CH2＝CH H CH3 CF3CF2
A233 CH2＝CHCH2 H CH3 CF3CF2
A234 CH3SO2N(CH3) H CH3 CF3CF2
A235 (CH3)2N H CH3 CF3CF2
A236 (CH3)2NSO2 H CH3 CF3CF2
A237 ClCH2 H CH3 CF3CF2
A238 CH3SCH2 H CH3 CF3CF2
A239 CH3SOCH2 H CH3 CF3CF2
A240 CH3SO2CH2 H CH3 CF3CF2
A241 H H CH3 CF3CF2CF2
A242 CH3 H CH3 CF3CF2CF2
A243 CH3CH2 H CH3 CF3CF2CF2
A244 环丙基 H CH3 CF3CF2CF2
A245 (CH3)3C H CH3 CF3CF2CF2
A246 (CH3)2CH H CH3 CF3CF2CF2
A247 CH3(CH2)2 H CH3 CF3CF2CF2
A248 CH3OCH2 H CH3 CF3CF2CF2
A249 CH3O(CH2)2 H CH3 CF3CF2CF2
A250 Ph H CH3 CF3CF2CF2
A251 PhO H CH3 CF3CF2CF2
A252 PhS H CH3 CF3CF2CF2
A253 PhSO H CH3 CF3CF2CF2
A254 PhSO2 H CH3 CF3CF2CF2
A255 CH3S H CH3 CF3CF2CF2
A256 CH3SO H CH3 CF3CF2CF2
A257 CF3 H CH3 CF3CF2CF2
化合物 R79 R80 R81 R82
序号
A258 F2CH H CH3 CF3CF2CF2
A259 HCC H CH3 CF3CF2CF2
A260 CH3CC H CH3 CF3CF2CF2
A261 CH2＝CH H CH3 CF3CF2CF2
A262 CH2＝CHCH2 H CH3 CF3CF2CF2
A263 CH3SO2N(CH3) H CH3 CF3CF2CF2
A264 (CH3)2N H CH3 CF3CF2CF2
A265 (CH3)2NSO2 H CH3 CF3CF2CF2
A266 ClCH2 H CH3 CF3CF2CF2
A267 CH3SCH2 H CH3 CF3CF2CF2
A268 CH3SOCH2 H CH3 CF3CF2CF2
A269 CH3SO2CH2 H CH3 CF3CF2CF2
A270 H H CH3 CF2Cl
A271 CH3 H CH3 CF2Cl
A272 CH3CH2 H CH3 CF2Cl
A273 环丙基 H CH3 CF2Cl
A274 (CH3)3C H CH3 CF2Cl
A275 (CH3)2CH H CH3 CF2Cl
A276 CH3(CH2)2 H CH3 CF2Cl
A277 CH3OCH2 H CH3 CF2Cl
A278 CH3O(CH2)2 H CH3 CF2Cl
A279 Ph H CH3 CF2Cl
A280 PhO H CH3 CF2Cl
A281 PhS H CH3 CF2Cl
A282 PhSO H CH3 CF2Cl
A283 PhSO2 H CH3 CF2Cl
A284 CH3S H CH3 CF2Cl
A285 CH3SO H CH3 CF2Cl
A286 CF3 H CH3 CF2Cl
A287 F2CH H CH3 CF2Cl
A288 HCC H CH3 CF2Cl
A289 CH3CC H CH3 CF2Cl
化合物 R79 R80 R81 R82
序号
A290 CH2＝CH H CH3 CF2Cl
A291 CH2＝CHCH2 H CH3 CF2Cl
A292 CH3SO2N(CH3) H CH3 CF2Cl
A293 (CH3)2N H CH3 CF2Cl
A294 (CH3)2NSO2 H CH3 CF2Cl
A295 ClCH2 H CH3 CF2Cl
A296 CH3SCH2 H CH3 CF2Cl
A297 CH3SOCH2 H CH3 CF2Cl
A298 CH3SO2CH2 H CH3 CF2Cl
A299 H H CH3 CHF2
A300 CH3 H CH3 CHF2
A301 CH3CH2 H CH3 CHF2
A302 环丙基 H CH3 CHF2
A303 (CH3)3C H CH3 CHF2
A304 (CH3)2CH H CH3 CHF2
A305 CH3(CH2)2 H CH3 CHF2
A306 CH3OCH2 H CH3 CHF2
A307 CH3O(CH2)2 H CH3 CHF2
A308 Ph H CH3 CHF2
A309 PhO H CH3 CHF2
A310 PhS H CH3 CHF2
A311 PhSO H CH3 CHF2
A312 PhSO2 H CH3 CHF2
A313 CH3S H CH3 CHF2
A314 CH3SO H CH3 CHF2
A315 CF3 H CH3 CHF2
A316 F2CH H CH3 CHF2
A317 HCC H CH3 CHF2
A318 CH3CC H CH3 CHF2
A319 CH2＝CH H CH3 CHF2
A320 CH2＝CHCH2 H CH3 CHF2
A321 CH3SO2N(CH3) H CH3 CHF2
化合物 R79 R80 R81 R82
序号
A322 (CH3)2N H CH3 CHF2
A323 (CH3)2NSO2 H CH3 CHF2
A324 ClCH2 H CH3 CHF2
A325 CH3SCH2 H CH3 CHF2
A326 CH3SOCH2 H CH3 CHF2
A327 CH3SO2CH2 H CH3 CHF2
A328 H H CH3 CCl3
A329 CH3 H CH3 CCl3
A330 CH3CH2 H CH3 CCl3
A331 (CH3)3C H CH3 CCl3
A332 (CH3)2CH H CH3 CCl3
A333 环丙基 H CH3 CCl3
A334 CH3(CH2)2 H CH3 CCl3
A335 CH3OCH2 H CH3 CCl3
A336 CH3O(CH2)2 H CH3 CCl3
A337 Ph H CH3 CCl3
A338 PhO H CH3 CCl3
A339 PhS H CH3 CCl3
A340 PhSO H CH3 CCl3
A341 PhSO2 H CH3 CCl3
A342 CH3S H CH3 CCl3
A343 CH3SO H CH3 CCl3
A344 CF3 H CH3 CCl3
A345 F2CH H CH3 CCl3
A346 HCC H CH3 CCl3
A347 CH3CC H CH3 CCl3
A348 CH2＝CH H CH3 CCl3
A349 CH2＝CHCH2 H CH3 CCl3
A350 CH3SO2N(CH3) H CH3 CCl3
A351 (CH3)2N H CH3 CCl3
A352 (CH3)2NSO2 H CH3 CCl3
A353 ClCH2 H CH3 CCl3
化合物 R79 R80 R81 R82
序号
A354 CH3SCH2 H CH3 CCl3
A355 CH3SOCH2 H CH3 CCl3
A356 CH3SO2CH2 H CH3 CCl3
A357 H H Ph CF3
A358 CH3 H Ph CF3
A359 CH3CH2 H Ph CF3
A360 环丙基 H Ph CF3
A361 (CH3)3C H Ph CF3
A362 (CH3)2CH H Ph CF3
A363 CH3(CH2)2 H Ph CF3
A364 CH3OCH2 H Ph CF3
A365 CH3O(CH2)2 H Ph CF3
A366 Ph H Ph CF3
A367 PhO H Ph CF3
A368 PhS H Ph CF3
A369 PhSO H Ph CF3
A370 PhSO2 H Ph CF3
A371 CH3S H Ph CF3
A372 CH3SO H Ph CF3
A373 CF3 H Ph CF3
A374 F2CH H Ph CF3
A375 HCC H Ph CF3
A376 CH3CC H Ph CF3
A377 CH2＝CH H Ph CF3
A378 CH2＝CHCH2 H Ph CF3
A379 CH3SO2N(CH3) H Ph CF3
A380 (CH3)2N H Ph CF3
A381 (CH3)2NSO2 H Ph CF3
A382 ClCH2 H Ph CF3
A383 CH3SCH2 H Ph CF3
A384 CH3SOCH2 H Ph CF3
A385 CH3SO2CH2 H Ph CF3
化合物 R79 R80 R81 R82
序号
A386 H H Ph CF3CF2
A387 CH3 H Ph CF3CF2
A388 CH3CH2 H Ph CF3CF2
A389 环丙基 H Ph CF3CF2
A390 (CH3)3C H Ph CF2CF2
A391 (CH3)2CH H Ph CF3CF2
A392 CH3(CH2)2 H Ph CF3CF2
A393 CH3OCH2 H Ph CF3CF2
A394 CH3O(CH2)2 H Ph CF3CF2
A395 Ph H Ph CF3CF2
A396 PhO H Ph CF3CF2
A397 PhS H Ph CF3CF2
A398 PhSO H Ph CF3CF2
A399 PhSO2 H Ph CF3CF2
A400 CH3S H Ph CF3CF2
A401 CH3SO H Ph CF3CF2
A402 CF3 H Ph CF3CF2
A403 F2CH H Ph CF3CF2
A404 HCC H Ph CF3CF2
A405 CH3CC H Ph CF3CF2
A406 CH2＝CH H Ph CF3CF2
A407 CH2＝CHCH2 H Ph CF3CF2
A408 CH3SO2N(CH3) H Ph CF3CF2
A409 (CH3)2N H Ph CF3CF2
A410 (CH3)2NSO2 H Ph CF3CF2
A411 ClCH2 H Ph CF3CF2
A412 CH3SCH2 H Ph CF3CF2
A413 CH3SOCH2 H Ph CF3CF2
A414 CH3SO2CH2 H Ph CF3CF2
A415 H H Ph CF3CF2CF2
A416 CH3 H Ph CF3CF2CF2
A417 CH3CH2 H Ph CF3CF2CF2
化合物 R79 R80 R81 R82
序号
A418 环丙基 H Ph CF3CF2CF2
A419 (CH3)3C H Ph CF3CF2CF2
A420 (CH3)2CH H Ph CF3CF2CF2
A421 CH3(CH2)2 H Ph CF3CF2CF2
A422 CH3OCH2 H Ph CF3CF2CF2
A423 CH3O(CH2)2 H Ph CF3CF2CF2
A424 Ph H Ph CF3CF2CF2
A425 PhO H Ph CF3CF2CF2
A426 PhS H Ph CF3CF2CF2
A427 PhSO H Ph CF3CF2CF2
A428 PhSO2 H Ph CF3CF2CF2
A429 CH3S H Ph CF3CF2CF2
A430 CH3SO H Ph CF3CF2CF2
A431 CF3 H Ph CF3CF2CF2
A432 F2CH H Ph CF3CF2CF2
A433 HCC H Ph CF3CF2CF2
A434 CH3CC H Ph CF3CF2CF2
A435 CH2＝CH H Ph CF3CF2CF2
A436 CH2＝CHCH2 H Ph CF3CF2CF2
A437 CH3SO2N(CH3) H Ph CF3CF2CF2
A438 (CH3)2N H Ph CF3CF2CF2
A439 (CH3)2NSO2 H Ph CF3CF2CF2
A440 ClCH2 H Ph CF3CF2CF2
A441 CH3SCH2 H Ph CF3CF2CF2
A442 CH3SOCH2 H Ph CF3CF2CF2
A443 CH3SO2CH2 H Ph CF3CF2CF2
A444 H H Ph CF2Cl
A445 CH3 H Ph CF2Cl
A446 CH3CH2 H Ph CF2Cl
A447 cyclopropyl H Ph CF2Cl
A448 (CH3)3C H Ph CF2Cl
A449 (CH3)2CH H Ph CF2Cl
化合物 R79 R80 R81 R82
序号
A450 CH3(CH2)2 H Ph CF2Cl
A451 CH3OCH2 H Ph CF2Cl
A452 CH3O(CH2)2 H Ph CF2Cl
A453 Ph H Ph CF2Cl
A454 PhO H Ph CF2Cl
A455 PhS H Ph CF2Cl
A456 PhSO H Ph CF2Cl
A457 PhSO2 H Ph CF2Cl
A458 CH3S H Ph CF2Cl
A459 CH3SO H Ph CF2Cl
A460 CF3 H Ph CF2Cl
A461 F2CH H Ph CF2Cl
A462 HCC H Ph CF2Cl
A463 CH3CC H Ph CF2Cl
A464 CH2＝CH H Ph CF2Cl
A465 CH2＝CHCH2 H Ph CF2Cl
A466 CH3SO2N(CH3) H Ph CF2Cl
A467 (CH3)2N H Ph CF2Cl
A468 (CH3)2NSO2 H Ph CF2Cl
A469 ClCH2 H Ph CF2Cl
A470 CH3SCH2 H Ph CF2Cl
A471 CH3SOCH2 H Ph CF2Cl
A472 CH3SO2CH2 H Ph CF2Cl
A473 H H Ph CHF2
A474 CH3 H Ph CHF2
A475 CH3CH2 H Ph CHF2
A476 环丙基 H Ph CHF2
A477 (CH3)3C H Ph CHF2
A478 (CH3)2CH H Ph CHF2
A479 CH3(CH2)2 H Ph CHF2
A480 CH3OCH2 H Ph CHF2
A481 CH3O(CH2)2 H Ph CHF2
化合物 R79 R80 R81 R82
序号
A482 Ph H Ph CHF2
A483 PhO H Ph CHF2
A484 PhS H Ph CHF2
A485 PhSO H Ph CHF2
A486 PhSO2 H Ph CHF2
A487 CH3S H Ph CHF2
A488 CH3SO H Ph CHF2
A489 CF3 H Ph CHF2
A490 F2CH H Ph CHF2
A491 HCC H Ph CHF2
A492 CH3CC H Ph CHF2
A493 CH2＝CH H Ph CHF2
A494 CH2＝CHCH2 H Ph CHF2
A495 CH3SO2N(CH3) H Ph CHF2
A496 (CH3)2N H Ph CHF2
A497 (CH3)2NSO2 H Ph CHF2
A498 ClCH2 H Ph CHF2
A499 CH3SCH2 H Ph CHF2
A500 CH3SOCH2 H Ph CHF2
A501 CH3SO2CH2 H Ph CHF2
A502 H H Ph CCl3
A503 CH3 H Ph CCl3
A504 CH3CH2 H Ph CCl3
A505 环丙基 H Ph CCl3
A506 (CH3)3C H Ph CCl3
A507 (CH3)2CH H Ph CCl3
A508 CH3(CH2)2 H Ph CCl3
A509 CH3OCH2 H Ph CCl3
A510 CH3O(CH2)2 H Ph CCl3
A511 Ph H Ph CCl3
A512 PhO H Ph CCl3
A513 PhS H Ph CCl3
化合物 R79 R80 R81 R82
序号
A514 PhSO H Ph CCl3
A515 PhSO2 H Ph CCl3
A516 CH3S H Ph CCl3
A517 CH3SO H Ph CCl3
A518 CF3 H Ph CCl3
A519 F2CH H Ph CCl3
A520 HCC H Ph CCl3
A521 CH3CC H Ph CCl3
A522 CH2＝CH H Ph CCl3
A523 CH2＝CHCH2 H Ph CCl3
A524 CH3SO2N(CH3) H Ph CCl3
A525 (CH3)2N H Ph CCl3
A526 (CH3)2NSO2 H Ph CCl3
A527 ClCH2 H Ph CCl3
A528 CH3SCH2 H Ph CCl3
A529 CH3SOCH2 H Ph CCl3
A530 CH3SO2CH2 H Ph CCl3
A531 H CH3 H CF3
A532 H CH3CH2 H CF3
A533 H 环丙基 H CF3
A534 H (CH3)3CH H CF3
A535 H (CH3)2CH H CF3
A536 H CH3(CH2)2 H CF3
A537 H CH3OCH2 H CF3
A538 H CH3O(CH2)2 H CF3
A539 H Ph H CF3
A540 H PhO H CF3
A541 H PhS H CF3
A542 H PhSO H CF3
A543 H PhSO2 H CF3
A544 H CH3S H CF3
A545 H CH3SO H CF3
化合物 R79 R80 R81 R82
序号
A546 H CF3 H CF3
A547 H F2CH H CF3
A548 H HCC H CF3
A549 H CH3CC H CF3
A550 H CH2＝CH H CF3
A551 H CH2＝CHCH2 H CF3
A552 H CH3SO2N(CH3) H CF3
A553 H (CH3)2N H CF3
A554 H (CH3)2NSO2 H CF3
A555 H CH3SCH2 H CF3
A556 H CH3SOCH2 H CF3
A557 H CH3SO2CH2 H CF3
A558 H CH3 H CF3CF2
A559 H CH3CH2 H CF3CF2
A560 H 环丙基 H CF3CF2
A561 H (CH3)3C H CF3CF2
A562 H (CH3)2CH H CF3CF2
A563 H CH3(CH2)2 H CF3CF2
A564 H CH3OCH2 H CF3CF2
A565 H CH3O(CH2)2 H CF3CF2
A566 H Ph H CF3CF2
A567 H PhO H CF3CF2
A568 H PhS H CF3CF2
A569 H PhSO H CF3CF2
A570 H PhSO2 H CF3CF2
A571 H CH3S H CF3CF2
A572 H CH3SO H CF3CF2
A573 H CF3 H CF3CF2
A574 H F2CH H CF3CF2
A575 H HCC H CF3CF2
A576 H CH3CC H CF3CF2
A577 H CH2＝CH H CF3CF2
化合物 R79 R80 R81 R82
序号
A578 H CH2＝CHCH2 H CF3CF2
A579 H CH3SO2N(CH3) H CF3CF2
A580 H (CH3)2N H CF3CF2
A581 H (CH3)2NSO2 H CF3CF2
A582 H CH3SCH2 H CF3CF2
A583 H CH3SOCH2 H CF3CF2
A584 H CH3SO2CH2 H CF3CF2
A585 H CH3 H CF3CF2CF2
A586 H CH3CH2 H CF3CF2CF2
A587 H 环丙基 H CF3CF2CF2
A588 H (CH3)3C H CF3CF2CF2
A589 H (CH3)2CH H CF3CF2CF2
A590 H CH3(CH2)2 H CF3CF2CF2
A591 H CH3OCH2 H CF3CF2CF2
A592 H CH3O(CH2)2 H CF3CF2CF2
A593 H Ph H CF3CF2CF2
A594 H PhO H CF3CF2CF2
A595 H PhS H CF3CF2CF2
A596 H PhSO H CF3CF2CF2
A597 H PhSO2 H CF3CF2CF2
A598 H CH3S H CF3CF2CF2
A599 H CH3SO H CF3CF2CF2
A600 H CF3 H CF3CF2CF2
A601 H F2CH H CF3CF2CF2
A602 H HCC H CF3CF2CF2
A603 H CH3CC H CF3CF2CF2
A604 H CH2＝CH H CF3CF2CF2
A605 H CH2＝CHCH2 H CF3CF2CF2
A606 H CH3SO2N(CH3) H CF3CF2CF2
A607 H (CH3)2N H CF3CF2CF2
A608 H (CH3)2NSO2 H CF3CF2CF2
A609 H CH3SCH2 H CF3CF2CF2
化合物 R79 R80 R81 R82
序号
A610 H CH3SOCH2 H CF3CF2CF2
A611 H CH3SO2CH2 H CF3CF2CF2
A612 H CH3 H CF2Cl
A613 H CH3CH2 H CF2Cl
A614 H 环丙基 H CF2Cl
A615 H (CH3)3C H CF2Cl
A616 H (CH3)2CH H CF2Cl
A617 H CH3(CH2)2 H CF2Cl
A618 H CH3OCH2 H CF2Cl
A619 H CH3O(CH2)2 H CF2Cl
A620 H Ph H CF2Cl
A621 H PhO H CF2Cl
A622 H PhS H CF2Cl
A623 H PhSO H CF2Cl
A624 H PhSO2 H CF2Cl
A625 H CH3S H CF2Cl
A626 H CH3SO H CF2Cl
A627 H CF3 H CF2Cl
A628 H F2CH H CF2Cl
A629 H HCC H CF2Cl
A630 H CH3CC H CF2Cl
A631 H CH2＝CH H CF2Cl
A632 H CH2＝CHCH2 H CF2Cl
A633 H CH3SO2N(CH3) H CF2Cl
A634 H (CH3)2N H CF2Cl
A635 H (CH3)2NSO2 H CF2Cl
A636 H CH3SCH2 H CF2Cl
A637 H CH3SOCH2 H CF2Cl
A638 H CH3SO2CH2 H CF2Cl
A639 H CH3 H CHF2
A640 H CH3CH2 H CHF2
A641 H 环丙基 H CHF2
化合物 R79 R80 R81 R82
序号
A642 H (CH3)3C H CHF2
A643 H (CH3)2CH H CHF2
A644 H CH3(CH2)2 H CHF2
A645 H CH3OCH2 H CHF2
A646 H CH3O(CH2)2 H CHF2
A647 H Ph H CHF2
A648 H PhO H CHF2
A649 H PhS H CHF2
A650 H PhSO H CHF2
A651 H PhSO2 H CHF2
A652 H CH3S H CHF2
A653 H CH3SO H CHF2
A654 H CF3 H CHF2
A655 H F2CH H CHF2
A656 H HCC H CHF2
A657 H CH3CC H CHF2
A658 H CH2＝CH H CHF2
A659 H CH2＝CHCH2 H CHF2
A660 H CH3SO2N(CH3) H CHF2
A661 H (CH3)2N H CHF2
A662 H (CH3)2NSO2 H CHF2
A663 H CH3SCH2 H CHF2
A664 H CH3SOCH2 H CHF2
A665 H CH3SO2CH2 H CHF2
A666 H CH3 H CCl3
A667 H CH3CH2 H CCl3
A668 H 环丙基 H CCl3
A669 H (CH3)3C H CCl3
A670 H (CH3)2CH H CCl3
A671 H CH3(CH2)2 H CCl3
A672 H CH3OCH2 H CCl3
A673 H CH3O(CH2)2 H CCl3
化合物 R79 R80 R81 R82
序号
A674 H Ph H CCl3
A675 H PhO H CCl3
A676 H PhS H CCl3
A677 H PhSO H CCl3
A678 H PhSO2 H CCl3
A679 H CH3S H CCl3
A680 H CH3SO H CCl3
A681 H CF3 H CCl3
A682 H F2CH H CCl3
A683 H HCC H CCl3
A684 H CH3CC H CCl3
A685 H CH2＝CH H CCl3
A686 H CH2＝CHCH2 H CCl3
A687 H CH3SO2N(CH3) H CCl3
A688 H (CH3)2N H CCl3
A689 H (CH3)2NSO2 H CCl3
A690 H CH3SCH2 H CCl3
A691 H CH3SOCH2 H CCl3
A692 H CH3SO2CH2 H CCl3
A693 H CH3 CH3 CF3
A694 H CH3CH2 CH3 CF3
A695 H 环丙基 CH3 CF3
A696 H (CH3)3C CH3 CF3
A697 H (CH3)2CH CH3 CF3
A698 H CH3(CH2)2 CH3 CF3
A699 H CH3OCH2 CH3 CF3
A700 H CH3O(CH2)2 CH3 CF3
A701 H Ph CH3 CF3
A702 H PhO CH3 CF3
A703 H PhS CH3 CF3
A704 H PhSO CH3 CF3
A705 H PhSO2 CH3 CF3
化合物 R79 R80 R81 R82
序号
A706 H CH3S CH3 CF3
A707 H CH3SO CH3 CF3
A708 H CF3 CH3 CF3
A709 H F2CH CH3 CF3
A710 H HCC CH3 CF3
A711 H CH3CC CH3 CF3
A712 H CH2＝CH CH3 CF3
A713 H CH2＝CHCH2 CH3 CF3
A714 H CH3SO2N(CH3) CH3 CF3
A715 H (CH3)2N CH3 CF3
A716 H (CH3)2NSO2 CH3 CF3
A717 H CH3SCH2 CH3 CF3
A718 H CH3SOCH2 CH3 CF3
A719 H CH3SO2CH2 CH3 CF3
A720 H CH3 CH3 CF3CF2
A721 H CH3CH2 CH3 CF3CF2
A722 H 环丙基 CH3 CF3CF2
A723 H (CH3)3C CH3 CF3CF2
A724 H (CH3)2CH CH3 CF3CF2
A725 H CH3(CH2)2 CH3 CF3CF2
A726 H CH3OCH2 CH3 CF3CF2
A727 H CH3O(CH2)2 CH3 CF3CF2
A728 H Ph CH3 CF3CF2
A729 H PhO CH3 CF3CF2
A730 H PhS CH3 CF3CF2
A731 H PhSO CH3 CF3CF2
A732 H PhSO2 CH3 CF3CF2
A733 H CH3S CH3 CF3CF2
A734 H CH3SO CH3 CF3CF2
A735 H CF3 CH3 CF3CF2
A736 H F2CH CH3 CF3CF2
A737 H HCC CH3 CF3CF2
化合物 R79 R80 R81 R82
序号
A738 H CH3CC CH3 CF3CF2
A739 H CH2＝CH CH3 CF3CF2
A740 H CH2＝CHCH2 CH3 CF3CF2
A741 H CH3SO2N(CH3) CH3 CF3CF2
A742 H (CH3)2N CH3 CF3CF2
A743 H (CH3)2NSO2 CH3 CF3CF2
A744 H CH3SCH2 CH3 CF3CF2
A745 H CH3SOCH2 CH3 CF3CF2
A746 H CH3SO2CH2 CH3 CF3CF2
A747 H CH3 CH3 CF3CF2CF2
A748 H CH3CH2 CH3 CF3CF2CF2
A749 H 环丙基 CH3 CF3CF2CF2
A750 H (CH3)3C CH3 CF3CF2CF2
A751 H (CH3)2CH CH3 CF3CF2CF2
A752 H CH3(CH2)2 CH3 CF3CF2CF2
A753 H CH3OCH2 CH3 CF3CF2CF2
A754 H CH3O(CH2)2 CH3 CF3CF2CF2
A755 H Ph CH3 CF3CF2CF2
A756 H PhO CH3 CF3CF2CF2
A757 H PhS CH3 CF3CF2CF2
A758 H PhSO CH3 CF3CF2CF2
A759 H PhSO2 CH3 CF3CF2CF2
A760 H CH3S CH3 CF3CF2CF2
A761 H CH3SO CH3 CF3CF2CF2
A762 H CF3 CH3 CF3CF2CF2
A763 H F2CH CH3 CF3CF2CF2
A764 H HCC CH3 CF3CF2CF2
A765 H CH3CC CH3 CF3CF2CF2
A766 H CH2＝CH CH3 CF3CF2CF2
A767 H CH2＝CHCH2 CH3 CF3CF2CF2
A768 H CH3SO2N(CH3) CH3 CF3CF2CF2
A769 H (CH3)2N CH3 CF3CF2CF2
化合物 R79 R80 R81 R82
序号
A770 H (CH3)2NSO2 CH3 CF3CF2CF2
A771 H CH3SCH2 CH3 CF3CF2CF2
A772 H CH3SOCH2 CH3 CF3CF2CF2
A773 H CH3SO2CH2 CH3 CF3CF2CF2
A774 H CH3 CH3 CF2Cl
A775 H CH3CH2 CH3 CF2Cl
A776 H 环丙基 CH3 CF2Cl
A777 H (CH3)3C CH3 CF2Cl
A778 H (CH3)2CH CH3 CF2Cl
A779 H CH3(CH2)2 CH3 CF2Cl
A780 H CH3OCH2 CH3 CF2Cl
A781 H CH3O(CH2)2 CH3 CF2Cl
A782 H Ph CH3 CF2Cl
A783 H PhO CH3 CF2Cl
A784 H PhS CH3 CF2Cl
A785 H PhSO CH3 CF2Cl
A786 H PhSO2 CH3 CF2Cl
A787 H CH3S CH3 CF2Cl
A788 H CH3SO CH3 CF2Cl
A789 H CF3 CH3 CF2Cl
A790 H F2CH CH3 CF2Cl
A791 H HCC CH3 CF2Cl
A792 H CH3CC CH3 CF2Cl
A793 H CH2＝CH CH3 CF2Cl
A794 H CH2＝CHCH2 CH3 CF2Cl
A795 H CH3SO2N(CH3) CH3 CF2Cl
A796 H (CH3)2N CH3 CF2Cl
A797 H (CH3)2NSO2 CH3 CF2Cl
A798 H CH3SCH2 CH3 CF2Cl
A799 H CH3SOCH2 CH3 CF2Cl
A800 H CH3SO2CH2 CH3 CF2Cl
A801 H CH3 CH3 CHF2
化合物 R79 R80 R81 R82
序号
A802 H CH3CH2 CH3 CHF2
A803 H 环丙基 CH3 CHF2
A804 H (CH3)3C CH3 CHF2
A805 H (CH3)2CH CH3 CHF2
A806 H CH3(CH2)2 CH3 CHF2
A807 H CH3OCH2 CH3 CHF2
A808 H CH3O(CH2)2 CH3 CHF2
A809 H Ph CH3 CHF2
A810 H PhO CH3 CHF2
A811 H PhS CH3 CHF2
A812 H PhSO CH3 CHF2
A813 H PhSO2 CH3 CHF2
A814 H CH3S CH3 CHF2
A815 H CH3SO CH3 CHF2
A816 H CF3 CH3 CHF2
A817 H F2CH CH3 CHF2
A818 H HCC CH3 CHF2
A819 H CH3CC CH3 CHF2
A820 H CH2＝CH CH3 CHF2
A821 H CH2＝CHCH2 CH3 CHF2
A822 H CH3SO2N(CH3) CH3 CHF2
A823 H (CH3)2N CH3 CHF2
A824 H (CH3)2NSO2 CH3 CHF2
A825 H CH3SCH2 CH3 CHF2
A826 H CH3SOCH2 CH3 CHF2
A827 H CH3SO2CH2 CH3 CHF2
A828 H CH3 CH3 CCl3
A829 H CH3CH2 CH3 CCl3
A830 H 环丙基 CH3 CCl3
A831 H (CH3)3C CH3 CCl3
A832 H (CH3)2CH CH3 CCl3
A833 H CH3(CH2)2 CH3 CCl3
化合物 R79 R80 R81 R82
序号
A834 H CH3OCH2 CH3 CCl3
A835 H CH3O(CH2)2 CH3 CCl3
A836 H Ph CH3 CCl3
A837 H PhO CH3 CCl3
A838 H PhS CH3 CCl3
A839 H PhSO CH3 CCl3
A840 H PhSO2 CH3 CCl3
A841 H CH3S CH3 CCl3
A842 H CH3SO CH3 CCl3
A843 H CF3 CH3 CCl3
A844 H F2CH CH3 CCl3
A845 H HCC CH3 CCl3
A846 H CH3CC CH3 CCl3
A847 H CH2＝CH CH3 CCl3
A848 H CH2＝CHCH2 CH3 CCl3
A849 H CH3SO2N(CH3) CH3 CCl3
A850 H (CH3)2N CH3 CCl3
A851 H (CH3)2NSO2 CH3 CCl3
A852 H CH3SCH2 CH3 CCl3
A853 H CH3SOCH2 CH3 CCl3
A854 H CH3SO2CH2 CH3 CCl3
A855 H CH3 Ph CF3
A856 H CH3CH2 Ph CF3
A857 H (CH3)2CH Ph CF3
A858 H (CH3)2CH Ph CF3
A859 H 环丙基 Ph CF3
A860 H CH3(CH2)2 Ph CF3
A861 H CH3OCH2 Ph CF3
A862 H CH3O(CH2)2 Ph CF3
A863 H Ph Ph CF3
A864 H PhO Ph CF3
A865 H PhS Ph CF3
化合物 R79 R80 R81 R82
序号
A866 H PhSO Ph CF3
A867 H PhSO2 Ph CF3
A868 H CH3S Ph CF3
A869 H CH3SO Ph CF3
A870 H CF3 Ph CF3
A871 H F2CH Ph CF3
A872 H HCC Ph CF3
A873 H CH3CC Ph CF3
A874 H CH2＝CH Ph CF3
A875 H CH2＝CHCH2 Ph CF3
A876 H CH3SO2N(CH3) Ph CF3
A877 H (CH3)2N Ph CF3
A878 H (CH3)2NSO2 Ph CF3
A879 H CH3SCH2 Ph CF3
A880 H CH3SOCH2 Ph CF3
A881 H CH3SO2CH2 Ph CF3
A882 H CH3 Ph CF3CF2
A883 H CH3CH2 Ph CF3CF2
A884 H 环丙基 Ph CF3CF2
A885 H (CH3)3C Ph CF3CF2
A886 H (CH3)2CH Ph CF3CF2
A887 H CH3(CH2)2 Ph CF3CF2
A888 H CH3OCH2 Ph CF3CF2
A889 H CH3O(CH2)2 Ph CF3CF2
A890 H Ph Ph CF3CF2
A891 H PhO Ph CF3CF2
A892 H PhS Ph CF3CF2
A893 H PhSO Ph CF3CF2
A894 H PhSO2 Ph CF3CF2
A895 H CH3S Ph CF3CF2
A896 H CH3SO Ph CF3CF2
A897 H CF3 Ph CF3CF2
化合物 R79 R80 R81 R82
序号
A898 H F2CH Ph CF3CF2
A899 H HCC Ph CF3CF2
A900 H CH3CC Ph CF3CF2
A901 H CH2＝CH Ph CF3CF2
A902 H CH2＝CHCH2 Ph CF3CF2
A903 H CH3SO2N(CH3) Ph CF3CF2
A904 H (CH3)2N Ph CF3CF2
A905 H (CH3)2NSO2 Ph CF3CF2
A906 H CH3SCH2 Ph CF3CF2
A907 H CH3SOCH2 Ph CF3CF2
A908 H CH3SO2CH2 Ph CF3CF2
A909 H CH3 Ph CF3CF2CF2
A910 H CH3CH2 Ph CF3CF2CF2
A911 H 环丙基 Ph CF3CF2CF2
A912 H (CH3)3C Ph CF3CF2CF2
A913 H (CH3)2CH Ph CF3CF2CF2
A914 H CH3(CH2)2 Ph CF3CF2CF2
A915 H CH3OCH2 Ph CF3CF2CF2
A916 H CH3O(CH2)2 Ph CF3CF2CF2
A917 H Ph Ph CF3CF2CF2
A918 H PhO Ph CF3CF2CF2
A919 H PhS Ph CF3CF2CF2
A920 H PhSO Ph CF3CF2CF2
A921 H PhSO2 Ph CF3CF2CF2
A922 H CH3S Ph CF3CF2CF2
A923 H CH3SO Ph CF3CF2CF2
A924 H CF3 Ph CF3CF2CF2
A925 H F2CH Ph CF3CF2CF2
A926 H HCC Ph CF3CF2CF2
A927 H CH3CC Ph CF3CF2CF2
A928 H CH2＝CH Ph CF3CF2CF2
A929 H CH2＝CHCH2 Ph CF3CF2CF2
化台物 R79 R80 R81 R82
序号
A930 H CH3SO2N(CH3) Ph CF3CF2CF2
A931 H (CH3)2N Ph CF3CF2CF2
A932 H (CH3)2NSO2 Ph CF3CF2CF2
A933 H CH3SCH2 Ph CF3CF2CF2
A934 H CH3SOCH2 Ph CF3CF2CF2
A935 H CH3SO2CH2 Ph CF3CF2CF2
A936 H CH3 Ph CF2Cl
A937 H CH3CH2 Ph CF2Cl
A938 H 环丙基 Ph CF2Cl
A939 H (CH3)3C Ph CF2Cl
A940 H (CH3)2CH Ph CF2Cl
A941 H CH3(CH2)2 Ph CF2Cl
A942 H CH3OCH2 Ph CF2Cl
A943 H CH3O(CH2)2 Ph CF2Cl
A944 H Ph Ph CF2Cl
A945 H PhO Ph CF2Cl
A946 H PhS Ph CF2Cl
A947 H PhSO Ph CF2Cl
A948 H PhSO2 Ph CF2Cl
A949 H CH3S Ph CF2Cl
A950 H CH3SO Ph CF2Cl
A951 H CF3 Ph CF2Cl
A952 H F2CH Ph CF2Cl
A953 H HCC Ph CF2Cl
A954 H CH3CC Ph CF2Cl
A955 H CH2＝CH Ph CF2Cl
A956 H CH2＝CHCH2 Ph CF2Cl
A957 H CH3SO2N(CH3) Ph CF2Cl
A958 H (CH3)2N Ph CF2Cl
A959 H (CH3)2NSO2 Ph CF2Cl
A960 H CH3SCH2 Ph CF2Cl
A961 H CH3SOCH2 Ph CF2Cl
化合物 R79 R80 R81 R82
序号
A962 H CH3SO2CH2 Ph CF2Cl
A963 H CH3 Ph CHF2
A964 H CH3CH2 Ph CHF2
A965 H (CH3)3C Ph CHF2
A966 H (CH3)2CH Ph CHF2
A967 H 环丙基 Ph CHF2
A968 H CH3(CH2)2 Ph CHF2
A969 H CH3OCH2 Ph CHF2
A970 H CH3O(CH2)2 Ph CHF2
A971 H Ph Ph CHF2
A972 H PhO Ph CHF2
A973 H PhS Ph CHF2
A974 H PhSO Ph CHF2
A975 H PhSO2 Ph CHF2
A976 H CH3S Ph CHF2
A977 H CH3SO Ph CHF2
A978 H CF3 Ph CHF2
A979 H F2CH Ph CHF2
A980 H HCC Ph CHF2
A981 H CH3CC Ph CHF2
A982 H CH2＝CH Ph CHF2
A983 H CH2＝CHCH2 Ph CHF2
A984 H CH3SO2N(CH3) Ph CHF2
A985 H (CH3)2N Ph CHF2
A986 H (CH3)2NSO2 Ph CHF2
A987 H CH3SCH2 Ph CHF2
A988 H CH3SOCH2 Ph CHF2
A989 H CH3SO2CH2 Ph CHF2
A990 H CH3 Ph CCl3
A991 H CH3CH2 Ph CCl3
A992 H (CH3)3C Ph CCl3
A993 H (CH3)2CH Ph CCl3
化合物 R79 R80 R81 R82
序号
A994 H 环丙基 Ph CCl3
A995 H CH3(CH2)2 Ph CCl3
A996 H CH3OCH2 Ph CCl3
A997 H CH3O(CH2)2 Ph CCl3
A998 H Ph Ph CCl3
A999 H PhO Ph CCl3
A1000 H PhS Ph CCl3
A1001 H PhSO Ph CCl3
A1002 H PhSO2 Ph CCl3
A1003 H CH3S Ph CCl3
A1004 H CH3SO Ph CCl3
A1005 H CF3 Ph CCl3
A1006 H F2CH Ph CCl3
A1007 H HCC Ph CCl3
A1008 H CH3CC Ph CCl3
A1009 H CH2＝CH Ph CCl3
A1010 H CH2＝CHCH2 Ph CCl3
A1011 H CH3SO2N(CH3) Ph CCl3
A1012 H (CH3)2N Ph CCl3
A1013 H (CH3)2NSO2 Ph CCl3
A1014 H CH3SCH2 Ph CCl3
A1015 H CH3SOCH2 Ph CCl3
A1016 H CH3SO2CH2 Ph CCl3
A1017 F H H CF3
A1018 Cl H H CF3
A1019 Br H H CF3
A1020 CN H H CF3
A1021 CH3SO2O H H CF3
A1022 CH3O H H CF3
A1023 CH2CH3O H H CF3
A1024 CH2CH＝CH2O H H CF3
A1025 HCCCH2O H H CF3
化合物 R79 R80 R81 R82
序号
A1026 S-苄基 H H CF3
A1027 SO2-苄基 H H CF3
A1028 ClCH2 H H CF3
A1029 BrCH2 H H CF3
A1030 FCH2 H H CF3
A1031 CHF2CH2 H H CF3
A1032 CF3CH2 H H CF3
A1033 三唑基甲基 H H CF3
A1034 CHCl2CH2 H H CF3
A1035 ClCH＝CH H H CF3
A1036 Cl2C＝CH H H CF3
A1037 CF3CH＝CH H H CF3
A1038 ClCC H H CF3
A1039 Ph H H CF3
A1040 CH3 CH3 H CF3
A1041 CH3 OH H CF3
A1042 CH3 F H CF3
A1043 CH3 Cl H CF3
A1044 F CH3 H CF3
A1045 Cl CH3 H CF3
A1046 H F H CF3
A1047 H Cl H CF3
A1048 H Br H CF3
A1049 H OH H CF3
A1050 H OCH3 H CF3
A1051 H OCHF2 H CF3
A1052 H OSO2CH3 H CF3
A1053 H OSO2CF3 H CF3
A1054 H ClCH2 H CF3
A1055 H BrCH2 H CF3
A1056 H FCH2 H CF3
A1057 H CHF2CH2 H CF3
化合物 R79 R80 R81 R82
序号
A1058 H CF3CH2 H CF3
A1059 H 三唑基甲基 H CF3
A1060 H CHCl2CH2 H CF3
A1061 H ClCH＝CH H CF3
A1062 H Cl2C＝CH H CF3
A1063 H CF3CH＝CH H CF3
A1064 H ClCC H CF3
A1065 H CH3C(O) H CF3
A1066 H 苯基 H CF3
A1067 H SO2CH3 H CF3
A1068 H SO2CF3 H CF3
A1069 H CN H CF3
A1070 H NO2 H CF3
A1071 CH3 H F CF3
A1072 CH3 H Cl CF3
A1073 CH3 H Br CF3
A1074 CH3 H CN CF3
A1075 CH3 H CH3O CF3
A1076 CH3 H CH3S CF3
A1077 CH3 H CH3SO CF3
A1078 CH3 H CH3SO2 CF3
在下表6中，Q是Q3
且Q3代表下列基团B：
表6：基团B：
基团 R44 R37 R38 R39 R40 W
B1 H H H H OH CH2
B2 CH3 H H H OH CH2
B3 CH3CH2 H H H OH CH2
B4 CH3CH2CH2 H H H OH CH2
B5 (CH3)2CH H H H OH CH2
B6 (CH3)3C H H H OH CH2
B7 CH3S H H H OH CH2
B8 CH3SO H H H OH CH2
B9 CH3SO2 H H H OH CH2
B10 Ph H H H OH CH2
B11 CH3O H H H OH CH2
B12 CH3CO2 H H H OH CH2
B13 CH3CH2CO2 H H H OH CH2
B14 CH2＝CHCH2 H H H OH CH2
B15 HCCCH2 H H H OH CH2
B16 CF3 H H H OH CH2
B17 (CH3)2NSO2 H H H OH CH2
B18 (CH3)2N H H H OH CH2
B19 PhO H H H OH CH2
B20 PhS H H H OH CH2
B21 PhSO H H H OH CH2
B22 PhSC2 H H H OH CH2
B23 CN H H H OH CH2
B24 CH3 CH3 H H OH CH2
B25 CH3CH2 CH3 H H OH CH2
B26 CH3CH2CH2 CH3 H H OH CH2
B27 (CH3)2CH CH3 H H OH CH2
B28 (CH3)3C CH3 H H OH CH2
B29 CH3S CH3 H H OH CH2
B30 CH3SO CH3 H H OH CH2
B31 CH3SO2 CH3 H H OH CH2
B32 Ph CH3 H H OH CH2
基团 R44 R37 R38 R39 R40 W
B33 CH3O CH3 H H OH CH2
B34 CH3CO2 CH3 H H OH CH2
B35 CH3CH2CO2 CH3 H H OH CH2
B36 CH2＝CHCH2 CH3 H H OH CH2
B37 HCCCH2 CH3 H H OH CH2
B38 CF3 CH3 H H OH CH2
B39 (CH3)2NSO2 CH3 H H OH CH2
B40 (CH3)2N CH3 H H OH CH2
B41 PhO CH3 H H OH CH2
B42 PhS CH3 H H OH CH2
B43 PhSO CH3 H H OH CH2
B44 PhSO2 CH3 H H OH CH2
B45 CN CH3 H H OH CH2
B46 CH3 H CH3 H OH CH2
B47 CH3CH2 H CH3 H OH CH2
B48 CH3CH2CH2 H CH3 H OH CH2
B49 (CH3)2CH H CH3 H OH CH2
B50 (CH3)3C H CH3 H OH CH2
B51 CH3S H CH3 H OH CH2
B52 CH3SO H CH3 H OH CH2
B53 CH3SO2 H CH3 H OH CH2
B54 Ph H CH3 H OH CH2
B55 CH3O H CH3 H OH CH2
B56 CH3CO2 H CH3 H OH CH2
B57 CH3CH2CO2 H CH3 H OH CH2
B58 CH2＝CHCH2 H CH3 H OH CH2
B59 HCCCH2 H CH3 H OH CH2
B60 CF3 H CH3 H OH CH2
B61 (CH3)2NSO2 H CH3 H OH CH2
B62 (CH3)2N H CH3 H OH CH2
B63 PhO H CH3 H OH CH2
B64 PhS H CH3 H OH CH2
B65 PhSO H CH3 H OH CH2
基团 R44 R37 R38 R39 R40 W
B66 PhSO2 H CH3 H OH CH2
B67 CN H CH3 H OH CH2
B68 CH3 CH3 CH3 H OH CH2
B69 CH3CH2 CH3 CH3 H OH CH2
B70 CH3CH2CH2 CH3 CH3 H OH CH2
B71 (CH3)2CH CH3 CH3 H OH CH2
B72 (CH3)3C CH3 CH3 H OH CH2
B73 CH3S CH3 CH3 H OH CH2
B74 CH3SO CH3 CH3 H OH CH2
B75 CH3SO2 CH3 CH3 H OH CH2
B76 Ph CH3 CH3 H OH CH2
B77 CH3O CH3 CH3 H OH CH2
B78 CH3CO2 CH3 CH3 H OH CH2
B79 CH3CH2CO2 CH3 CH3 H OH CH2
B80 CH2＝CHCH2 CH3 CH3 H OH CH2
B81 HCCCH2 CH3 CH3 H OH CH2
B82 CF3 CH3 CH3 H OH CH2
B83 (CH3)2NSO2 CH3 CH3 H OH CH2
B84 (CH3)2N CH3 CH3 H OH CH2
B85 PhO CH3 CH3 H OH CH2
B86 PhS CH3 CH3 H OH CH2
B87 PhSO CH3 CH3 H OH CH2
B88 PhSO2 CH3 CH3 H OH CH2
B89 CN CH3 CH3 H OH CH2
B90 CH3 CH3 CH3 CH3 OH CH2
B91 CH3CH2 CH3 CH3 CH3 OH CH2
B92 CH3CH2CH2 CH3 CH3 CH3 OH CH2
B93 (CH3)2CH CH3 CH3 CH3 OH CH2
B94 (CH3)3C CH3 CH3 CH3 OH CH2
B95 CH3S CH3 CH3 CH3 OH CH2
B96 CH3SO CH3 CH3 CH3 OH CH2
B97 CH3SO2 CH3 CH3 CH3 OH CH2
B98 Ph CH3 CH3 CH3 OH CH2
基团 R44 R37 R38 R39 R40 W
B99 CH3O CH3 CH3 CH3 OH CH2
B100 CH3CO2 CH3 CH3 CH3 OH CH2
B101 CH3CH2CO2 CH3 CH3 CH3 OH CH2
B102 CH2＝CHCH2 CH3 CH3 CH3 OH CH2
B103 HCCCH2 CH3 CH3 CH3 OH CH2
B104 CF3 CH3 CH3 CH3 OH CH2
B105 (CH3)2NSO2 CH3 CH3 CH3 OH CH2
B106 (CH3)2N CH3 CH3 CH3 OH CH2
B107 PhO CH3 CH3 CH3 OH CH2
B108 PhS CH3 CH3 CH3 OH CH2
B109 PhSO CH3 CH3 CH3 OH CH2
B110 PhSO2 CH3 CH3 CH3 OH CH2
B111 CN CH3 CH3 CH3 OH CH2
B112 CH3CH2 CH3CH2 H H OH CH2
B113 CH3CH2CH2 CH3CH2 H H OH CH2
B114 (CH3)2CH CH3CH2 H H OH CH2
B115 (CH3)3C CH3CH2 H H OH CH2
B116 CH3S CH3CH2 H H OH CH2
B117 CH3SO CH3CH2 H H OH CH2
B118 CH3SO2 CH3CH2 H H OH CH2
B119 Ph CH3CH2 H H OH CH2
B120 CH3O CH3CH2 H H OH CH2
B121 CH3CO2 CH3CH2 H H OH CH2
B122 CH3CH2CO2 CH3CH2 H H OH CH2
B123 CH2＝CHCH2 CH3CH2 H H OH CH2
B124 HCCCH2 CH3CH2 H H OH CH2
B125 CF3 CH3CH2 H H OH CH2
B126 (CH3)2NSO2 CH3CH2 H H OH CH2
B127 (CH3)2N CH3CH2 H H OH CH2
B128 PhO CH3CH2 H H OH CH2
B129 PhS CH3CH2 H H OH CH2
B130 PhSO CH3CH2 H H OH CH2
B131 PhSO2 CH3CH2 H H OH CH2
基团 R44 R37 R38 R39 R40 W
B132 CN CH3CH2 H H OH CH2
B133 H H H H OH CHCH3
B134 CH3 H H H OH CHCH3
B135 CH3CH2 H H H OH CHCH3
B136 CH3CH2CH2 H H H OH CHCH3
B137 (CH3)2CH H H H OH CHCH3
B138 (CH3)3C H H H OH CHCH3
B139 CH3S H H H OH CHCH3
B140 CH3SO H H H OH CHCH3
B141 CH3SO2 H H H OH CHCH3
B142 Ph H H H OH CHCH3
B143 CH3O H H H OH CHCH3
B144 CH3CO2 H H H OH CHCH3
B145 CH3CH2CO2 H H H OH CHCH3
B146 CH2＝CHCH2 H H H OH CHCH3
B147 HCCCH2 H H H OH CHCH3
B148 CF3 H H H OH CHCH3
B149 (CH3)2NSO2 H H H OH CHCH3
B150 (CH3)2N H H H OH CHCH3
B151 PhO H H H OH CHCH3
B152 PhS H H H OH CHCH3
B153 PhSO H H H OH CHCH3
B154 PhSO2 H H H OH CHCH3
B155 CN H H H OH CHCH3
B156 CH3 CH3 H H OH CHCH3
B157 CH3CH2 CH3 H H OH CHCH3
B158 CH3CH2CH2 CH3 H H OH CHCH3
B159 (CH3)2CH CH3 H H OH CHCH3
B160 (CH3)3C CH3 H H OH CHCH3
B161 CH3S CH3 H H OH CHCH3
B162 CH3SO CH3 H H OH CHCH3
B163 CH3SO2 CH3 H H OH CHCH3
B164 Ph CH3 H H OH CHCH3
基团 R44 R37 R38 R39 R40 W
B165 CH3O CH3 H H OH CHCH3
B166 CH3CO2 CH3 H H OH CHCH3
B167 CH3CH2CO2 CH3 H H OH CHCH3
B168 CH2＝CHCH2 CH3 H H OH CHCH3
B169 HCCCH2 CH3 H H OH CHCH3
B170 CF3 CH3 H H OH CHCH3
B171 (CH3)2NSO2 CH3 H H OH CHCH3
B172 (CH3)2N CH3 H H OH CHCH3
B173 PhO CH3 H H OH CHCH3
B174 PhS CH3 H H OH CHCH3
B175 PhSO CH3 H H OH CHCH3
B176 PhSO2 CH3 H H OH CHCH3
B177 CN CH3 H H OH CHCH3
B178 CH3 H CH3 H OH CHCH3
B179 CH3CH2 H CH3 H OH CHCH3
B180 CH3CH2CH2 H CH3 H OH CHCH3
B181 (CH3)2CH H CH3 H OH CHCH3
B182 (CH3)3C H CH3 H OH CHCH3
B183 CH3S H CH3 H OH CHCH3
B184 CH3SO H CH3 H OH CHCH3
B185 CH3SO2 H CH3 H OH CHCH3
B186 Ph H CH3 H OH CHCH3
B187 CH3O H CH3 H OH CHCH3
B188 CH3CO2 H CH3 H OH CHCH3
B189 CH3CH2CO2 H CH3 H OH CHCH3
B190 CH2＝CHCH2 H CH3 H OH CHCH3
B191 HCCCH2 H CH3 H OH CHCH3
B192 CF3 H CH3 H OH CHCH3
B193 (CH3)2NSO2 H CH3 H OH CHCH3
B194 (CH3)2N H CH3 H OH CHCH3
B195 PhO H CH3 H OH CHCH3
B196 PhS H CH3 H OH CHCH3
B197 PhSO H CH3 H OH CHCH3
基团 R44 R37 R38 R39 R40 W
B198 PhSO2 H CH3 H OH CHCH3
B199 CN H CH3 H OH CHCH3
B200 CH3 CH3 CH3 H OH CHCH3
B201 CH3CH2 CH3 CH3 H OH CHCH3
B202 CH3CH2CH2 CH3 CH3 H OH CHCH3
B203 (CH3)2CH CH3 CH3 H OH CHCH3
B204 (CH3)3C CH3 CH3 H OH CHCH3
B205 CH3S CH3 CH3 H OH CHCH3
B206 CH3SO CH3 CH3 H OH CHCH3
B207 CH3SO2 CH3 CH3 H OH CHCH3
B208 Ph CH3 CH3 H OH CHCH3
B209 CH3O CH3 CH3 H OH CHCH3
B210 CH3CO2 CH3 CH3 H OH CHCH3
B211 CH3CH2CO2 CH3 CH3 H OH CHCH3
B212 CH2＝CHCH2 CH3 CH3 H OH CHCH3
B213 HCCCH2 CH3 CH3 H OH CHCH3
B214 CF3 CH3 CH3 H OH CHCH3
B215 (CH3)2NSO2 CH3 CH3 H OH CHCH3
B216 (CH3)2N CH3 CH3 H OH CHCH3
B217 PhO CH3 CH3 H OH CHCH3
B218 PhS CH3 CH3 H OH CHCH3
B219 PhSO CH3 CH3 H OH CHCH3
B220 PhSO2 CH3 CH3 H OH CHCH3
B221 CN CH3 CH3 H OH CHCH3
B222 CH3 CH3 CH3 CH3 OH CHCH3
B223 CH3CH2 CH3 CH3 CH3 OH CHCH3
B224 CH3CH2CH2 CH3 CH3 CH3 OH CHCH3
B225 (CH3)2CH CH3 CH3 CH3 OH CHCH3
B226 (CH3)3C CH3 CH3 CH3 OH CHCH3
B227 CH3S CH3 CH3 CH3 OH CHCH3
B228 CH3SO CH3 CH3 CH3 OH CHCH3
B229 CH3SO2 CH3 CH3 CH3 OH CHCH3
B230 Ph CH3 CH3 CH3 OH CHCH3
基团 R44 R37 R38 R39 R40 W
B231 CH3O CH3 CH3 CH3 OH CHCH3
B232 CH3CO2 CH3 CH3 CH3 OH CHCH3
B233 CH3CH2CO2 CH3 CH3 CH3 OH CHCH3
B234 CH2＝CHCH2 CH3 CH3 CH3 OH CHCH3
B235 HCCCH2 CH3 CH3 CH3 OH CHCH3
B236 CF3 CH3 CH3 CH3 OH CHCH3
B237 (CH3)2NSO2 CH3 CH3 CH3 OH CHCH3
B238 (CH3)2N CH3 CH3 CH3 OH CHCH3
B239 PhO CH3 CH3 CH3 OH CHCH3
B240 PhS CH3 CH3 CH3 OH CHCH3
B241 PhSO CH3 CH3 CH3 OH CHCH3
B242 PhSO2 CH3 CH3 CH3 OH CHCH3
B243 CN CH3 CH3 CH3 OH CHCH3
B244 CH3CH2 CH3CH2 H H OH CHCH3
B245 CH3CH2CH2 CH3CH2 H H OH CHCH3
B246 (CH3)2CH CH3CH2 H H OH CHCH3
B247 (CH3)3C CH3CH2 H H OH CHCH3
B248 CH3S CH3CH2 H H OH CHCH3
B249 CH3SO CH3CH2 H H OH CHCH3
B250 CH3SO2 CH3CH2 H H OH CHCH3
B251 Ph CH3CH2 H H OH CHCH3
B252 CH3O CH3CH2 H H OH CHCH3
B253 CH3CO2 CH3CH2 H H OH CHCH3
B254 CH3CH2CO2 CH3CH2 H H OH CHCH3
B255 CH2＝CHCH2 CH3CH2 H H OH CHCH3
B256 HCCCH2 CH3CH2 H H OH CHCH3
B257 CF3 CH3CH2 H H OH CHCH3
B258 (CH3)2NSO2 CH3CH2 H H OH CHCH3
B259 (CH3)2N CH3CH2 H H OH CHCH3
B260 PhO CH3CH2 H H OH CHCH3
B261 PhS CH3CH2 H H OH CHCH3
B262 PhSO CH3CH2 H H OH CHCH3
B263 PhSO2 CH3CH2 H H OH CHCH3
基团 R44 R37 R38 R39 R40 W
B264 CN CH3CH2 H H OH CHCH3
B265 H H H H OH C＝O
B266 CH3 H H H OH C＝O
B267 CH3CH2 H H H OH C＝O
B268 CH3CH2CH2 H H H OH C＝O
B269 (CH3)2CH H H H OH C＝O
B270 (CH3)3C H H H OH C＝O
B271 CH3S H H H OH C＝O
B272 CH3SO H H H OH C＝O
B273 CH3SO2 H H H OH C＝O
B274 Ph H H H OH C＝O
B275 CH3O H H H OH C＝O
B276 CH3CO2 H H H OH C＝O
B277 CH3CH2CO2 H H H OH C＝O
B278 CH2＝CHCH2 H H H OH C＝O
B279 HCCCH2 H H H OH C＝O
B280 CF3 H H H OH C＝O
B281 (CH3)2NSO2 H H H OH C＝O
B282 (CH3)2N H H H OH C＝O
B283 PhO H H H OH C＝O
B284 PhS H H H OH C＝O
B285 PhSO H H H OH C＝O
B286 PhSO2 H H H OH C＝O
B287 CN H H H OH C＝O
B288 CH3 CH3 H H OH C＝O
B289 CH3CH2 CH3 H H OH C＝O
B290 CH3CH2CH2 CH3 H H OH C＝O
B291 (CH3)2CH CH3 H H OH C＝O
B292 (CH3)3C CH3 H H OH C＝O
B293 CH3S CH3 H H OH C＝O
B294 CH3SO CH3 H H OH C＝O
B295 CH3SO2 CH3 H H OH C＝O
B296 Ph CH3 H H OH C＝O
基团 R44 R37 R38 R39 R40 W
B297 CH3O CH3 H H OH C＝O
B298 CH3CO2 CH3 H H OH C＝O
B299 CH3CH2CO2 CH3 H H OH C＝O
B300 CH2＝CHCH2 CH3 H H OH C＝O
B301 HCCCH2 CH3 H H OH C＝O
B302 CF3 CH3 H H OH C＝O
B303 (CH3)2NSO2 CH3 H H OH C＝O
B304 (CH3)2N CH3 H H OH C＝O
B305 PhO CH3 H H OH C＝O
B306 PhS CH3 H H OH C＝O
B307 PhSO CH3 H H OH C＝O
B308 PhSO2 CH3 H H OH C＝O
B309 CN CH3 H H OH C＝O
B310 CH3 H CH3 H OH C＝O
B311 CH3CH2 H CH3 H OH C＝O
B312 CH3CH2CH2 H CH3 H OH C＝O
B313 (CH3)2CH H CH3 H OH C＝O
B314 (CH3)3C H CH3 H OH C＝O
B315 CH3S H CH3 H OH C＝O
B316 CH3SO H CH3 H OH C＝O
B317 CH3SO2 H CH3 H OH C＝O
B318 Ph H CH3 H OH C＝O
B319 CH3O H CH3 H OH C＝O
B320 CH3CO2 H CH3 H OH C＝O
B321 CH3CH2CO2 H CH3 H OH C＝O
B322 CH2＝CHCH2 H CH3 H OH C＝O
B323 HCCCH2 H CH3 H OH C＝O
B324 CF3 H CH3 H OH C＝O
B325 (CH3)2NSO2 H CH3 H OH C＝O
B326 (CH3)2N H CH3 H OH C＝O
B327 PhO H CH3 H OH C＝O
B328 PhS H CH3 H OH C＝O
B329 PhSO H CH3 H OH C＝O
基团 R44 R37 R38 R39 R40 W
B330 PhSO2 H CH3 H OH C＝O
B331 CN H CH3 H OH C＝O
B332 CH3 CH3 CH3 H OH C＝O
B333 CH3CH2 CH3 CH3 H OH C＝O
B334 CH3CH2CH2 CH3 CH3 H OH C＝O
B335 (CH3)2CH CH3 CH3 H OH C＝O
B336 (CH3)3C CH3 CH3 H OH C＝O
B337 CH3S CH3 CH3 H OH C＝O
B338 CH3SO CH3 CH3 H OH C＝O
B339 CH3SO2 CH3 CH3 H OH C＝O
B340 Ph CH3 CH3 H OH C＝O
B341 CH3O CH3 CH3 H OH C＝O
B342 CH3CO2 CH3 CH3 H OH C＝O
B343 CH3CH2CO2 CH3 CH3 H OH C＝O
B344 CH2＝CHCH2 CH3 CH3 H OH C＝O
B345 HCCCH2 CH3 CH3 H OH C＝O
B346 CF3 CH3 CH3 H OH C＝O
B347 (CH3)2NSO2 CH3 CH3 H OH C＝O
B348 (CH3)2N CH3 CH3 H OH C＝O
B349 PhO CH3 CH3 H OH C＝O
B350 PhS CH3 CH3 H OH C＝O
B351 PhSO CH3 CH3 H OH C＝O
B352 PhSO2 CH3 CH3 H OH C＝O
B353 CN CH3 CH3 H OH C＝O
B354 CH3 CH3 CH3 CH3 OH C＝O
B355 CH3CH2 CH3 CH3 CH3 OH C＝O
B356 CH3CH2CH2 CH3 CH3 CH3 OH C＝O
B357 (CH3)2CH CH3 CH3 CH3 OH C＝O
B358 (CH3)3C CH3 CH3 CH3 OH C＝O
B359 CH3S CH3 CH3 CH3 OH C＝O
B360 CH3SO CH3 CH3 CH3 OH C＝O
B361 CH3SO2 CH3 CH3 CH3 OH C＝O
B362 Ph CH3 CH3 CH3 OH C＝O
基团 R44 R37 R38 R39 R40 W
B363 CH3O CH3 CH3 CH3 OH C＝O
B364 CH3CO2 CH3 CH3 CH3 OH C＝O
B365 CH3CH2CO2 CH3 CH3 CH3 OH C＝O
B366 CH2＝CHCH2 CH3 CH3 CH3 OH C＝O
B367 HCCCH2 CH3 CH3 CH3 OH C＝O
B368 CF3 CH3 CH3 CH3 OH C＝O
B369 (CH3)2NSO2 CH3 CH3 CH3 OH C＝O
B370 (CH3)2N CH3 CH3 CH3 OH C＝O
B371 PhO CH3 CH3 CH3 OH C＝O
B372 PhS CH3 CH3 CH3 OH C＝O
B373 PhSO CH3 CH3 CH3 OH C＝O
B374 PhSO2 CH3 CH3 CH3 OH C＝O
B375 CN CH3 CH3 CH3 OH C＝O
B376 CH3CH2 CH3CH2 H H OH C＝O
B377 CH3CH2CH2 CH3CH2 H H OH C＝O
B378 (CH3)2CH CH3CH2 H H OH C＝O
B379 (CH3)3C CH3CH2 H H OH C＝O
B380 CH3S CH3CH2 H H OH C＝O
B381 CH3SO CH3CH2 H H OH C＝O
B382 CH3SO2 CH3CH2 H H OH C＝O
B383 Ph CH3CH2 H H OH C＝O
B384 CH3O CH3CH2 H H OH C＝O
B385 CH3CO2 CH3CH2 H H OH C＝O
B386 CH3CH2CO2 CH3CH2 H H OH C＝O
B387 CH2＝CHCH2 CH3CH2 H H OH C＝O
B388 HCCCH2 CH3CH2 H H OH C＝O
B389 CF3 CH3CH2 H H OH C＝O
B390 (CH3)2NSO2 CH3CH2 H H OH C＝O
B391 (CH3)2N CH3CH2 H H OH C＝O
B392 PhO CH3CH2 H H OH C＝O
B393 PhS CH3CH2 H H OH C＝O
B394 PhSO CH3CH2 H H OH C＝O
B395 PhSO2 CH3CH2 H H OH C＝O
基团 R44 R37 R38 R39 R40 W
B396 CN CH3CH2 H H OH C＝O
B397 H H H H OH N-CH3
B398 CH3 H H H OH N-CH3
B399 CH3CH2 H H H OH N-CH3
B400 CH3CH2CH2 H H H OH N-CH3
B401 (CH3)2CH H H H OH N-CH3
B402 (CH3)3C H H H OH N-CH3
B403 CH3S H H H OH N-CH3
B404 CH3SO H H H OH N-CH3
B405 CH3SO2 H H H OH N-CH3
B406 Ph H H H OH N-CH3
B407 CH3O H H H OH N-CH3
B408 CH3CO2 H H H OH N-CH3
B409 CH3CH2CO2 H H H OH N-CH3
B410 CH2＝CHCH2 H H H OH N-CH3
B411 HCCCH2 H H H OH N-CH3
B412 CF3 H H H OH N-CH3
B413 (CH3)2NSO2 H H H OH N-CH3
B414 (CH3)2N H H H OH N-CH3
B415 PhO H H H OH N-CH3
B416 PhS H H H OH N-CH3
B417 PhSO H H H OH N-CH3
B418 PhSO2 H H H OH N-CH3
B419 CN H H H OH N-CH3
B420 CH3 CH3 H H OH N-CH3
B421 CH3CH2 CH3 H H OH N-CH3
B422 CH3CH2CH2 CH3 H H OH N-CH3
B423 (CH3)2CH CH3 H H OH N-CH3
B424 (CH3)3C CH3 H H OH N-CH3
B425 CH3S CH3 H H OH N-CH3
B426 CH3SO CH3 H H OH N-CH3
B427 CH3SO2 CH3 H H OH N-CH3
B428 Ph CH3 H H OH N-CH3
基团 R44 R37 R38 R39 R40 W
B429 CH3O CH3 H H OH N-CH3
B430 CH3CO2 CH3 H H OH N-CH3
B431 CH3CH2CO2 CH3 H H OH N-CH3
B432 CH2＝CHCH2 CH3 H H OH N-CH3
B433 HCCCH2 CH3 H H OH N-CH3
B434 CF3 CH3 H H OH N-CH3
B435 (CH3)2NSO2 CH3 H H OH N-CH3
B436 (CH3)2N CH3 H H OH N-CH3
B437 PhO CH3 H H OH N-CH3
B438 PhS CH3 H H OH N-CH3
B439 PhSO CH3 H H OH N-CH3
B440 PhSO2 CH3 H H OH N-CH3
B441 CN CH3 H H OH N-CH3
B442 CH3 H CH3 H OH N-CH3
B443 CH3CH2 H CH3 H OH N-CH3
B444 CH3CH2CH2 H CH3 H OH N-CH3
B445 (CH3)2CH H CH3 H OH N-CH3
B446 (CH3)3C H CH3 H OH N-CH3
B447 CH3S H CH3 H OH N-CH3
B448 CH3SO H CH3 H OH N-CH3
B449 CH3SO2 H CH3 H OH N-CH3
B450 Ph H CH3 H OH N-CH3
B451 CH3O H CH3 H OH N-CH3
B452 CH3CO2 H CH3 H OH N-CH3
B453 CH3CH2CO2 H CH3 H OH N-CH3
B454 CH2＝CHCH2 H CH3 H OH N-CH3
B455 HCCCH2 H CH3 H OH N-CH3
B456 CF3 H CH3 H OH N-CH3
B457 (CH3)2NSO2 H CH3 H OH N-CH3
B458 (CH3)2N H CH3 H OH N-CH3
B459 PhO H CH3 H OH N-CH3
B460 PhS H CH3 H OH N-CH3
B461 PhSO H CH3 H OH N-CH3
基团 R44 R37 R38 R39 R40 W
B462 PhSO2 H CH3 H OH N-CH3
B463 CN H CH3 H OH N-CH3
B464 CH3 CH3 CH3 H OH N-CH3
B465 CH3CH2 CH3 CH3 H OH N-CH3
B466 CH3CH2CH2 CH3 CH3 H OH N-CH3
B467 (CH3)2CH CH3 CH3 H OH N-CH3
B468 (CH3)3C CH3 CH3 H OH N-CH3
B469 CH3S CH3 CH3 H OH N-CH3
B470 CH3SO CH3 CH3 H OH N-CH3
B471 CH3SO2 CH3 CH3 H OH N-CH3
B472 Ph CH3 CH3 H OH N-CH3
B473 CH3O CH3 CH3 H OH N-CH3
B474 CH3CO2 CH3 CH3 H OH N-CH3
B475 CH3CH2CO2 CH3 CH3 H OH N-CH3
B476 CH2＝CHCH2 CH3 CH3 H OH N-CH3
B477 HCCCH2 CH3 CH3 H OH N-CH3
B478 CF3 CH3 CH3 H OH N-CH3
B479 (CH3)2NSO2 CH3 CH3 H OH N-CH3
B480 (CH3)2N CH3 CH3 H OH N-CH3
B481 PhO CH3 CH3 H OH N-CH3
B482 PhS CH3 CH3 H OH N-CH3
B483 PhSO CH3 CH3 H OH N-CH3
B484 PhSO2 CH3 CH3 H OH N-CH3
B485 CN CH3 CH3 H OH N-CH3
B486 CH3 CH3 CH3 CH3 OH N-CH3
B487 CH3CH2 CH3 CH3 CH3 OH N-CH3
B488 CH3CH2CH2 CH3 CH3 CH3 OH N-CH3
B489 (CH3)2CH CH3 CH3 CH3 OH N-CH3
B490 (CH3)3C CH3 CH3 CH3 OH N-CH3
B491 CH3S CH3 CH3 CH3 OH N-CH3
B492 CH3SO CH3 CH3 CH3 OH N-CH3
B493 CH3SO2 CH3 CH3 CH3 OH N-CH3
B494 Ph CH3 CH3 CH3 OH N-CH3
基团 R44 R37 R38 R39 R40 W
B495 CH3O CH3 CH3 CH3 OH N-CH3
B496 CH3CO2 CH3 CH3 CH3 OH N-CH3
B497 CH3CH2CO2 CH3 CH3 CH3 OH N-CH3
B498 CH2＝CHCH2 CH3 CH3 CH3 OH N-CH3
B499 HCCCH2 CH3 CH3 CH3 OH N-CH3
B500 CF3 CH3 CH3 CH3 OH N-CH3
B501 (CH3)2NSO2 CH3 CH3 CH3 OH N-CH3
B502 (CH3)2N CH3 CH3 CH3 OH N-CH3
B503 PhO CH3 CH3 CH3 OH N-CH3
B504 PhS CH3 CH3 CH3 OH N-CH3
B505 PhSO CH3 CH3 CH3 OH N-CH3
B506 PhSO2 CH3 CH3 CH3 OH N-CH3
B507 CN CH3 CH3 CH3 OH N-CH3
B508 CH3CH2 CH3CH2 H H OH N-CH3
B509 CH3CH2CH2 CH3CH2 H H OH N-CH3
B510 (CH3)2CH CH3CH2 H H OH N-CH3
B511 (CH3)3C CH3CH2 H H OH N-CH3
B512 CH3S CH3CH2 H H OH N-CH3
B513 CH3SO CH3CH2 H H OH N-CH3
B514 CH3SO2 CH3CH2 H H OH N-CH3
B515 Ph CH3CH2 H H OH N-CH3
B516 CH3O CH3CH2 H H OH N-CH3
B517 CH3CO2 CH3CH2 H H OH N-CH3
B518 CH3CH2CO2 CH3CH2 H H OH N-CH3
B519 CH2＝CHCH2 CH3CH2 H H OH N-CH3
B520 HCCCH2 CH3CH2 H H OH N-CH3
B521 CF3 CH3CH2 H H OH N-CH3
B522 (CH3)2NSO2 CH3CH2 H H OH N-CH3
B523 (CH3)2N CH3CH2 H H OH N-CH3
B524 PhO CH3CH2 H H OH N-CH3
B525 PhS CH3CH2 H H OH N-CH3
B526 PhSO CH3CH2 H H OH N-CH3
B527 PhSO2 CH3CH2 H H OH N-CH3
基团 R44 R37 R38 R39 R40 W
B528 CN CH3CH2 H H OH N-CH3
B529 H H H H OH O
B530 CH3 H H H OH O
B531 CH3CH2 H H H OH O
B532 CH3CH2CH2 H H H OH O
B533 (CH3)2CH H H H OH O
B534 (CH3)3C H H H OH O
B535 CH3S H H H OH O
B536 CH3SO H H H OH O
B537 CH3SO2 H H H OH O
B538 Ph H H H OH O
B539 CH3O H H H OH O
B540 CH3CO2 H H H OH O
B541 CH3CH2CO2 H H H OH O
B542 CH2＝CHCH2 H H H OH O
B543 HCCCH2 H H H OH O
B544 CF3 H H H OH O
B545 (CH3)2NSO2 H H H OH O
B546 (CH3)2N H H H OH O
B547 PhO H H H OH O
B548 PhS H H H OH O
B549 PhSO H H H OH O
B550 PhSO2 H H H OH O
B551 CN H H H OH O
B552 CH3 CH3 H H OH O
B553 CH3CH2 CH3 H H OH O
B554 CH3CH2CH2 CH3 H H OH O
B555 (CH3)2CH CH3 H H OH O
B556 (CH3)3C CH3 H H OH O
B557 CH3S CH3 H H OH O
B558 CH3SO CH3 H H OH O
B559 CH3SO2 CH3 H H OH O
B560 Ph CH3 H H OH O
基团 R44 R37 R38 R39 R40 W
B561 CH3O CH3 H H OH O
B562 CH3CO2 CH3 H H OH O
B563 CH3CH2CO2 CH3 H H OH O
B564 CH2＝CHCH2 CH3 H H OH O
B565 HCCCH2 CH3 H H OH O
B566 CF3 CH3 H H OH O
B567 (CH3)2NSO2 CH3 H H OH O
B568 (CH3)2N CH3 H H OH O
B569 PhO CH3 H H OH O
B570 PhS CH3 H H OH O
B571 PhSO CH3 H H OH O
B572 PhSO2 CH3 H H OH O
B573 CN CH3 H H OH O
B574 CH3 H CH3 H OH O
B575 CH3CH2 H CH3 H OH O
B576 CH3CH2CH2 H CH3 H OH O
B577 (CH3)2CH H CH3 H OH O
B578 (CH3)3C H CH3 H OH O
B579 CH3S H CH3 H OH O
B580 CH3SO H CH3 H OH O
B581 CH3SO2 H CH3 H OH O
B582 Ph H CH3 H OH O
B583 CH3O H CH3 H OH O
B584 CH3CO2 H CH3 H OH O
B585 CH3CH2CO2 H CH3 H OH O
B586 CH2＝CHCH2 H CH3 H OH O
B587 HCCCH2 H CH3 H OH O
B588 CF3 H CH3 H OH O
B589 (CH3)2NSO2 H CH3 H OH O
B590 (CH3)2N H CH3 H OH O
B591 PhO H CH3 H OH O
B592 PhS H CH3 H OH O
B593 PhSO H CH3 H OH O
基团 R44 R37 R38 R39 R40 W
B594 PhSO2 H CH3 H OH O
B595 CN H CH3 H OH O
B596 CH3 CH3 CH3 H OH O
B597 CH3CH2 CH3 CH3 H OH O
B598 CH3CH2CH2 CH3 CH3 H OH O
B599 (CH3)2CH CH3 CH3 H OH O
B600 (CH3)3C CH3 CH3 H OH O
B601 CH3S CH3 CH3 H OH O
B602 CH3SO CH3 CH3 H OH O
B603 CH3SO2 CH3 CH3 H OH O
B604 Ph CH3 CH3 H OH O
B605 CH3O CH3 CH3 H OH O
B606 CH3CO2 CH3 CH3 H OH O
B607 CH3CH2CO2 CH3 CH3 H OH O
B608 CH2＝CHCH2 CH3 CH3 H OH O
B609 HCCCH2 CH3 CH3 H OH O
B610 CF3 CH3 CH3 H OH O
B611 (CH3)2NSO2 CH3 CH3 H OH O
B612 (CH3)2N CH3 CH3 H OH O
B613 PhO CH3 CH3 H OH O
B614 PhS CH3 CH3 H OH O
B615 PhSO CH3 CH3 H OH O
B616 PhSO2 CH3 CH3 H OH O
B617 CN CH3 CH3 H OH O
B618 CH3 CH3 CH3 CH3 OH O
B619 CH3CH2 CH3 CH3 CH3 OH O
B620 CH3CH2CH2 CH3 CH3 CH3 OH O
B621 (CH3)2CH CH3 CH3 CH3 OH O
B622 (CH3)3C CH3 CH3 CH3 OH O
B623 CH3S CH3 CH3 CH3 OH O
B624 CH3SO CH3 CH3 CH3 OH O
B625 CH3SO2 CH3 CH3 CH3 OH O
B626 Ph CH3 CH3 CH3 OH O
基团 R44 R37 R38 R39 R40 W
B627 CH3O CH3 CH3 CH3 OH O
B628 CH3CO2 CH3 CH3 CH3 OH O
B629 CH3CH2CO2 CH3 CH3 CH3 OH O
B630 CH2＝CHCH2 CH3 CH3 CH3 OH O
B631 HCCCH2 CH3 CH3 CH3 OH O
B632 CF3 CH3 CH3 CH3 OH O
B633 (CH3)2NSO2 CH3 CH3 CH3 OH O
B634 (CH3)2N CH3 CH3 CH3 OH O
B635 PhO CH3 CH3 CH3 OH O
B636 PhS CH3 CH3 CH3 OH O
B637 PhSO CH3 CH3 CH3 OH O
B638 PhSO2 CH3 CH3 CH3 OH O
B639 CN CH3 CH3 CH3 OH O
B640 CH3CH2 CH3CH2 H H OH O
B641 CH3CH2CH2 CH3CH2 H H OH O
B642 (CH3)2CH CH3CH2 H H OH O
B643 (CH3)3C CH3CH2 H H OH O
B644 CH3S CH3CH2 H H OH O
B645 CH3SO CH3CH2 H H OH O
B646 CH3SO2 CH3CH2 H H OH O
B647 Ph CH3CH2 H H OH O
B648 CH3O CH3CH2 H H OH O
B649 CH3CO2 CH3CH2 H H OH O
B650 CH3CH2CO2 CH3CH2 H H OH O
B651 CH2＝CHCH2 CH3CH2 H H OH O
B652 HCCCH2 CH3CH2 H H OH O
B653 CF3 CH3CH2 H H OH O
B654 (CH3)2NSO2 CH3CH2 H H OH O
B655 (CH3)2N CH3CH2 H H OH O
B656 PhO CH3CH2 H H OH O
B657 PhS CH3CH2 H H OH O
B658 PhSO CH3CH2 H H OH O
B659 PhSO2 CH3CH2 H H OH O
基团 R44 R37 R38 R39 R40 W
B660 CN CH3CH2 H H OH O
B661 H H H H OH S
B662 CH3 H H H OH S
B663 CH3CH2 H H H OH S
B664 CH3CH2CH2 H H H OH S
B665 (CH3)2CH H H H OH S
B666 (CH3)3C H H H OH S
B667 CH3S H H H OH S
B668 CH3SO H H H OH S
B669 CH3SO2 H H H OH S
B670 Ph H H H OH S
B671 CH3O H H H OH S
B672 CH3CO2 H H H OH S
B673 CH3CH2CO2 H H H OH S
B674 CH2＝CHCH2 H H H OH S
B675 HCCCH2 H H H OH S
B676 CF3 H H H OH S
B677 (CH3)2NSO2 H H H OH S
B678 (CH3)2N H H H OH S
B679 PhO H H H OH S
B680 PhS H H H OH S
B681 PhSO H H H OH S
B682 PhSO2 H H H OH S
B683 CN H H H OH S
B684 CH3 CH3 H H OH S
B685 CH3CH2 CH3 H H OH S
B686 CH3CH2CH2 CH3 H H OH S
B687 (CH3)2CH CH3 H H OH S
B688 (CH3)3C CH3 H H OH S
B689 CH3S CH3 H H OH S
B690 CH3SO CH3 H H OH S
B691 CH3SO2 CH3 H H OH S
B692 Ph CH3 H H OH S
基团 R44 R37 R38 R39 R40 W
B693 CH3O CH3 H H OH S
B694 CH3CO2 CH3 H H OH S
B695 CH3CH2CO2 CH3 H H OH S
B696 CH2＝CHCH2 CH3 H H OH S
B697 HCCCH2 CH3 H H OH S
B698 CF3 CH3 H H OH S
B699 (CH3)2NSO2 CH3 H H OH S
B700 (CH3)2N CH3 H H OH S
B701 PhO CH3 H H OH S
B702 PhS CH3 H H OH S
B703 PhSO CH3 H H OH S
B704 PhSO2 CH3 H H OH S
B705 CN CH3 H H OH S
B706 CH3 H CH3 H OH S
B707 CH3CH2 H CH3 H OH S
B708 CH3CH2CH2 H CH3 H OH S
B709 (CH3)2CH H CH3 H OH S
B710 (CH3)3C H CH3 H OH S
B711 CH3S H CH3 H OH S
B712 CH3SO H CH3 H OH S
B713 CH3SO2 H CH3 H OH S
B714 Ph H CH3 H OH S
B715 CH3O H CH3 H OH S
B716 CH3CO2 H CH3 H OH S
B717 CH3CH2CO2 H CH3 H OH S
B718 CH2＝CHCH2 H CH3 H OH S
B719 HCCCH2 H CH3 H OH S
B720 CF3 H CH3 H OH S
B721 (CH3)2NSO2 H CH3 H OH S
B722 (CH3)2N H CH3 H OH S
B723 PhO H CH3 H OH S
B724 PhS H CH3 H OH S
B725 PhSO H CH3 H OH S
基团 R44 R37 R38 R39 R40 W
B726 PhSO2 H CH3 H OH S
B727 CN H CH3 H OH S
B728 CH3 CH3 CH3 H OH S
B729 CH3CH2 CH3 CH3 H OH S
B730 CH3CH2CH2 CH3 CH3 H OH S
B731 (CH3)2CH CH3 CH3 H OH S
B732 (CH3)3C CH3 CH3 H OH S
B733 CH3S CH3 CH3 H OH S
B734 CH3SO CH3 CH3 H OH S
B735 CH3SO2 CH3 CH3 H OH S
B736 Ph CH3 CH3 H OH S
B737 CH3O CH3 CH3 H OH S
B738 CH3CO2 CH3 CH3 H OH S
B739 CH3CH2CO2 CH3 CH3 H OH S
B740 CH2＝CHCH2 CH3 CH3 H OH S
B741 HCCCH2 CH3 CH3 H OH S
B742 CF3 CH3 CH3 H OH S
B743 (CH3)2NSO2 CH3 CH3 H OH S
B744 (CH3)2N CH3 CH3 H OH S
B745 PhO CH3 CH3 H OH S
B746 PhS CH3 CH3 H OH S
B747 PhSO CH3 CH3 H OH S
B748 PhSO2 CH3 CH3 H OH S
B749 CN CH3 CH3 H OH S
B750 CH3 CH3 CH3 CH3 OH S
B751 CH3CH2 CH3 CH3 CH3 OH S
B752 CH3CH2CH2 CH3 CH3 CH3 OH S
B753 (CH3)2CH CH3 CH3 CH3 OH S
B754 (CH3)3C CH3 CH3 CH3 OH S
B755 CH3S CH3 CH3 CH3 OH S
B756 CH3SO CH3 CH3 CH3 OH S
B757 CH3SO2 CH3 CH3 CH3 OH S
B758 Ph CH3 CH3 CH3 OH S
基团 R44 R37 R38 R39 R40 W
B759 CH3O CH3 CH3 CH3 OH S
B760 CH3CO2 CH3 CH3 CH3 OH S
B761 CH3CH2CO2 CH3 CH3 CH3 OH S
B762 CH2＝CHCH2 CH3 CH3 CH3 OH S
B763 HCCCH2 CH3 CH3 CH3 OH S
B764 CF3 CH3 CH3 CH3 OH S
B765 (CH3)2NSO2 CH3 CH3 CH3 OH S
B766 (CH3)2N CH3 CH3 CH3 OH S
B767 PhO CH3 CH3 CH3 OH S
B768 PhS CH3 CH3 CH3 OH S
B769 PhSO CH3 CH3 CH3 OH S
B770 PhSO2 CH3 CH3 CH3 OH S
B771 CN CH3 CH3 CH3 OH S
B772 CH3CH2 CH3CH2 H H OH S
B773 CH3CH2CH2 CH3CH2 H H OH S
B774 (CH3)2CH CH3CH2 H H OH S
B775 (CH3)3C CH3CH2 H H OH S
B776 CH3S CH3CH2 H H OH S
B777 CH3SO CH3CH2 H H OH S
B778 CH3SO2 CH3CH2 H H OH S
B779 Ph CH3CH2 H H OH S
B780 CH3O CH3CH2 H H OH S
B781 CH3CO2 CH3CH2 H H OH S
B782 CH3CH2CO2 CH3CH2 H H OH S
B783 CH2＝CHCH2 CH3CH2 H H OH S
B784 HCCCH2 CH3CH2 H H OH S
B785 CF3 CH3CH2 H H OH S
B786 (CH3)2NSO2 CH3CH2 H H OH S
B787 (CH3)2N CH3CH2 H H OH S
B788 PhO CH3CH2 H H OH S
B789 PhS CH3CH2 H H OH S
B790 PhSO CH3CH2 H H OH S
B791 PhSO2 CH3CH2 H H OH S
基团 R44 R37 R38 R39 R40 W
B792 CN CH3CH2 H H OH S
B793 H H H H OH SO2
B794 CH3 H H H OH SO2
B795 CH3CH2 H H H OH SO2
B796 CH3CH2CH2 H H H OH SO2
B797 (CH3)2CH H H H OH SO2
B798 (CH3)3C H H H OH SO2
B799 CH3S H H H OH SO2
B800 CH3SO H H H OH SO2
B801 CH3SO2 H H H OH SO2
B802 Ph H H H OH SO2
B803 CH3O H H H OH SO2
B804 CH3CO2 H H H OH SO2
B805 CH3CH2CO2 H H H OH SO2
B806 CH2＝CHCH2 H H H OH SO2
B807 HCCCH2 H H H OH SO2
B808 CF3 H H H OH SO2
B809 (CH3)2NSO2 H H H OH SO2
B810 (CH3)2N H H H OH SO2
B811 PhO H H H OH SO2
B812 PhS H H H OH SO2
B813 PhSO H H H OH SO2
B814 PhSO2 H H H OH SO2
B815 CN H H H OH SO2
B816 CH3 CH3 H H OH SO2
B817 CH3CH2 CH3 H H OH SO2
B818 CH3CH2CH2 CH3 H H OH SO2
B819 (CH3)2CH CH3 H H OH SO2
B820 (CH3)3C CH3 H H OH SO2
B821 CH3S CH3 H H OH SO2
B822 CH3SO CH3 H H OH SO2
B823 CH3SO2 CH3 H H OH SO2
B824 Ph CH3 H H OH SO2
基团 R44 R37 R38 R39 R40 W
B825 CH3O CH3 H H OH SO2
B826 CH3CO2 CH3 H H OH SO2
B827 CH3CH2CO2 CH3 H H OH SO2
B828 CH2＝CHCH2 CH3 H H OH SO2
B829 HCCCH2 CH3 H H OH SO2
B830 CF3 CH3 H H OH SO2
B831 (CH3)2NSO2 CH3 H H OH SO2
B832 (CH3)2N CH3 H H OH SO2
B833 PhO CH3 H H OH SO2
B834 PhS CH3 H H OH SO2
B835 PhSO CH3 H H OH SO2
B836 PhSO2 CH3 H H OH SO2
B837 CN CH3 H H OH SO2
B838 CH3 H CH3 H OH SO2
B839 CH3CH2 H CH3 H OH SO2
B840 CH3CH2CH2 H CH3 H OH SO2
B841 (CH3)2CH H CH3 H OH SO2
B842 (CH3)3C H CH3 H OH SO2
B843 CH3S H CH3 H OH SO2
B844 CH3SO H CH3 H OH SO2
B845 CH3SO2 H CH3 H OH SO2
B846 Ph H CH3 H OH SO2
B847 CH3O H CH3 H OH SO2
B848 CH3CO2 H CH3 H OH SO2
B849 CH3CH2CO2 H CH3 H OH SO2
B850 CH2＝CHCH2 H CH3 H OH SO2
B851 HCCCH2 H CH3 H OH SO2
B852 CF3 H CH3 H OH SO2
B853 (CH3)2NSO2 H CH3 H OH SO2
B854 (CH3)2N H CH3 H OH SO2
B855 PhO H CH3 H OH SO2
B856 PhS H CH3 H OH SO2
B857 PhSO H CH3 H OH SO2
基团 R44 R37 R38 R39 R40 W
B858 PhSO2 H CH3 H OH SO2
B859 CN H CH3 H OH SO2
B860 CH3 CH3 CH3 H OH SO2
B861 CH3CH2 CH3 CH3 H OH SO2
B862 CH3CH2CH2 CH3 CH3 H OH SO2
B863 (CH3)2CH CH3 CH3 H OH SO2
B864 (CH3)3C CH3 CH3 H OH SO2
B865 CH3S CH3 CH3 H OH SO2
B866 CH3SO CH3 CH3 H OH SO2
B867 CH3SO2 CH3 CH3 H OH SO2
B868 Ph CH3 CH3 H OH SO2
B869 CH3O CH3 CH3 H OH SO2
B870 CH3CO2 CH3 CH3 H OH SO2
B871 CH3CH2CO2 CH3 CH3 H OH SO2
B872 CH2＝CHCH2 CH3 CH3 H OH SO2
B873 HCCCH2 CH3 CH3 H OH SO2
B874 CF3 CH3 CH3 H OH SO2
B875 (CH3)2NSO2 CH3 CH3 H OH SO2
B876 (CH3)2N CH3 CH3 H OH SO2
B877 PhO CH3 CH3 H OH SO2
B878 PhS CH3 CH3 H OH SO2
B879 PhSO CH3 CH3 H OH SO2
B880 PhSO2 CH3 CH3 H OH SO2
B881 CN CH3 CH3 H OH SO2
B882 CH3 CH3 CH3 CH3 OH SO2
B883 CH3CH2 CH3 CH3 CH3 OH SO2
B884 CH3CH2CH2 CH3 CH3 CH3 OH SO2
B885 (CH3)2CH CH3 CH3 CH3 OH SO2
B886 (CH3)3C CH3 CH3 CH3 OH SO2
B887 CH3S CH3 CH3 CH3 OH SO2
B888 CH3SO CH3 CH3 CH3 OH SO2
B889 CH3SO2 CH3 CH3 CH3 OH SO2
B890 Ph CH3 CH3 CH3 OH SO2
基团 R44 R37 R38 R39 R40 W
B891 CH3O CH3 CH3 CH3 OH SO2
B892 CH3CO2 CH3 CH3 CH3 OH SO2
B893 CH3CH2CO2 CH3 CH3 CH3 OH SO2
B894 CH2＝CHCH2 CH3 CH3 CH3 OH SO2
B895 HCCCH2 CH3 CH3 CH3 OH SO2
B896 CF3 CH3 CH3 CH3 OH SO2
B897 (CH3)2NSO2 CH3 CH3 CH3 OH SO2
B898 (CH3)2N CH3 CH3 CH3 OH SO2
B899 PhO CH3 CH3 CH3 OH SO2
B900 PhS CH3 CH3 CH3 OH SO2
B901 PhSO CH3 CH3 CH3 OH SO2
B902 PhSO2 CH3 CH3 CH3 OH SO2
B903 CN CH3 CH3 CH3 OH SO2
B904 CH3CH2 CH3CH2 H H OH SO2
B905 CH3CH2CH2 CH3CH2 H H OH SO2
B906 (CH3)2CH CH3CH2 H H OH SO2
B907 (CH3)3C CH3CH2 H H OH SO2
B908 CH3S CH3CH2 H H OH SO2
B909 CH3SO CH3CH2 H H OH SO2
B910 CH3SO2 CH3CH2 H H OH SO2
B911 Ph CH3CH2 H H OH SO2
B912 CH3O CH3CH2 H H OH SO2
B913 CH3CO2 CH3CH2 H H OH SO2
B914 CH3CH2CO2 CH3CH2 H H OH SO2
B915 CH2＝CHCH2 CH3CH2 H H OH SO2
B916 HCCCH2 CH3CH2 H H OH SO2
B917 CF3 CH3CH2 H H OH SO2
B918 (CH3)2NSO2 CH3CH2 H H OH SO2
B919 (CH3)2N CH3CH2 H H OH SO2
B920 PhO CH3CH2 H H OH SO2
B921 PhS CH3CH2 H H OH SO2
B922 PhSO CH3CH2 H H OH SO2
B923 PhSO2 CH3CH2 H H OH SO2
基团 R44 R37 R38 R39 R40 W
B924 CN CH3CH2 H H OH SO2
B925 H H H H OH CH(CO2CH2CH3)
B926 CH3 H H H OH CH(CO2CH2CH3)
B927 CH3CH2 H H H OH CH(CO2CH2CH3)
B928 CH3CH2CH2 H H H OH CH(CO2CH2CH3)
B929 (CH3)2CH H H H OH CH(CO2CH2CH3)
B930 (CH3)3C H H H OH CH(CO2CH2CH3)
B931 CH3S H H H OH CH(CO2CH2CH3)
B932 CH3SO H H H OH CH(CO2CH2CH3)
B933 CH3SO2 H H H OH CH(CO2CH2CH3)
B934 Ph H H H OH CH(CO2CH2CH3)
B935 CH3O H H H OH CH(CO2CH2CH3)
B936 CH3CO2 H H H OH CH(CO2CH2CH3)
B937 CH3CH2CO2 H H H OH CH(CO2CH2CH3)
B938 CH2＝CHCH2 H H H OH CH(CO2CH2CH3)
B939 HCCCH2 H H H OH CH(CO2CH2CH3)
B940 CF3 H H H OH CH(CO2CH2CH3)
B941 (CH3)2NSO2 H H H OH CH(CO2CH2CH3)
B942 (CH3)2N H H H OH CH(CO2CH2CH3)
B943 PhO H H H OH CH(CO2CH2CH3)
B944 PhS H H H OH CH(CO2CH2CH3)
B945 PhSO H H H OH CH(CO2CH2CH3)
B946 PhSO2 H H H OH CH(CO2CH2CH3)
B947 CN H H H OH CH(CO2CH2CH3)
B948 CH3 CH3 H H OH CH(CO2CH2CH3)
B949 CH3CH2 CH3 H H OH CH(CO2CH2CH3)
B950 CH3CH2CH2 CH3 H H OH CH(CO2CH2CH3)
B951 (CH3)2CH CH3 H H OH CH(CO2CH2CH3)
B952 (CH3)3C CH3 H H OH CH(CO2CH2CH3)
B953 CH3S CH3 H H OH CH(CO2CH2CH3)
B954 CH3SO CH3 H H OH CH(CO2CH2CH3)
B955 CH3SO2 CH3 H H OH CH(CO2CH2CH3)
B956 Ph CH3 H H OH CH(CO2CH2CH3)
基团 R44 R37 R38 R39 R40 W
B957 CH3O CH3 H H OH CH(CO2CH2CH3)
B958 CH3CO2 CH3 H H OH CH(CO2CH2CH3)
B959 CH3CH2CO2 CH3 H H OH CH(CO2CH2CH3)
B960 CH2＝CHCH2 CH3 H H OH CH(CO2CH2CH3)
B961 HCCCH2 CH3 H H OH CH(CO2CH2CH3)
B962 CF3 CH3 H H OH CH(CO2CH2CH3)
B963 (CH3)2NSO2 CH3 H H OH CH(CO2CH2CH3)
B964 (CH3)2N CH3 H H OH CH(CO2CH2CH3)
B965 PhO CH3 H H OH CH(CO2CH2CH3)
B966 PhS CH3 H H OH CH(CO2CH2CH3)
B967 PhSO CH3 H H OH CH(CO2CH2CH3)
B968 PhSO2 CH3 H H OH CH(CO2CH2CH3)
B969 CN CH3 H H OH CH(CO2CH2CH3)
B970 CH3 H CH3 H OH CH(CO2CH2CH3)
B971 CH3CH2 H CH3 H OH CH(CO2CH2CH3)
B972 CH3CH2CH2 H CH3 H OH CH(CO2CH2CH3)
B973 (CH3)2CH H CH3 H OH CH(CO2CH2CH3)
B974 (CH3)3C H CH3 H OH CH(CO2CH2CH3)
B975 CH3S H CH3 H OH CH(CO2CH2CH3)
B976 CH3SO H CH3 H OH CH(CO2CH2CH3)
B977 CH3SO2 H CH3 H OH CH(CO2CH2CH3)
B978 Ph H CH3 H OH CH(CO2CH2CH3)
B979 CH3O H CH3 H OH CH(CO2CH2CH3)
B980 CH3CO2 H CH3 H OH CH(CO2CH2CH3)
B981 CH3CH2CO2 H CH3 H OH CH(CO2CH2CH3)
B982 CH2＝CHCH2 H CH3 H OH CH(CO2CH2CH3)
B983 HCCCH2 H CH3 H OH CH(CO2CH2CH3)
B984 CF3 H CH3 H OH CH(CO2CH2CH3)
B985 (CH3)2NSO2 H CH3 H OH CH(CO2CH2CH3)
B986 (CH3)2N H CH3 H OH CH(CO2CH2CH3)
B987 PhO H CH3 H OH CH(CO2CH2CH3)
B988 PhS H CH3 H OH CH(CO2CH2CH3)
B989 PhSO H CH3 H OH CH(CO2CH2CH3)
基团 R44 R37 R38 R39 R40 W
B990 PhSO2 H CH3 H OH CH(CO2CH2CH3)
B991 CN H CH3 H OH CH(CO2CH2CH3)
B992 CH3 CH3 CH3 H OH CH(CO2CH2CH3)
B993 CH3CH2 CH3 CH3 H OH CH(CO2CH2CH3)
B994 CH3CH2CH2 CH3 CH3 H OH CH(CO2CH2CH3)
B995 (CH3)2CH CH3 CH3 H OH CH(CO2CH2CH3)
B996 (CH3)3C CH3 CH3 H OH CH(CO2CH2CH3)
B997 CH3S CH3 CH3 H OH CH(CO2CH2CH3)
B998 CH3SO CH3 CH3 H OH CH(CO2CH2CH3)
B999 CH3SO2 CH3 CH3 H OH CH(CO2CH2CH3)
B1000 Ph CH3 CH3 H OH CH(CO2CH2CH3)
B1001 CH3O CH3 CH3 H OH CH(CO2CH2CH3)
B1002 CH3CO2 CH3 CH3 H OH CH(CO2CH2CH3)
B1003 CH3CH2CO2 CH3 CH3 H OH CH(CO2CH2CH3)
B1004 CH2＝CHCH2 CH3 CH3 H OH CH(CO2CH2CH3)
B1005 HCCCH2 CH3 CH3 H OH CH(CO2CH2CH3)
B1006 CF3 CH3 CH3 H OH CH(CO2CH2CH3)
B1007 (CH3)2NSO2 CH3 CH3 H OH CH(CO2CH2CH3)
B1008 (CH3)2N CH3 CH3 H OH CH(CO2CH2CH3)
B1009 PhO CH3 CH3 H OH CH(CO2CH2CH3)
B1010 PhS CH3 CH3 H OH CH(CO2CH2CH3)
B1011 PhSO CH3 CH3 H OH CH(CO2CH2CH3)
B1012 PhSO2 CH3 CH3 H OH CH(CO2CH2CH3)
B1013 CN CH3 CH3 H OH CH(CO2CH2CH3)
B1014 CH3 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1015 CH3CH2 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1016 CH3CH2CH2 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1017 (CH3)2CH CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1018 (CH3)3C CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1019 CH3S CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1020 CH3SO CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1021 CH3SO2 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1022 Ph CH3 CH3 CH3 OH CH(CO2CH2CH3)
基团 R44 R37 R38 R39 R40 W
B1023 CH3O CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1024 CH3CO2 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1025 CH3CH2CO2 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1026 CH2＝CHCH2 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1027 HCCCH2 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1028 CF3 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1029 (CH3)2NSO2 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1030 (CH3)2N CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1031 PhO CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1032 PhS CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1033 PhSO CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1034 PhSO2 CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1035 CN CH3 CH3 CH3 OH CH(CO2CH2CH3)
B1036 CH3CH2 CH3CH2 H H OH CH(CO2CH2CH3)
B1037 CH3CH2CH2 CH3CH2 H H OH CH(CO2CH2CH3)
B1038 (CH3)2CH CH3CH2 H H OH CH(CO2CH2CH3)
B1039 (CH3)3C CH3CH2 H H OH CH(CO2CH2CH3)
B1040 CH3S CH3CH2 H H OH CH(CO2CH2CH3)
B1041 CH3SO CH3CH2 H H OH CH(CO2CH2CH3)
B1042 CH3SO2 CH3CH2 H H OH CH(CO2CH2CH3)
B1043 Ph CH3CH2 H H OH CH(CO2CH2CH3)
B1044 CH3O CH3CH2 H H OH CH(CO2CH2CH3)
B1045 CH3CO2 CH3CH2 H H OH CH(CO2CH2CH3)
B1046 CH3CH2CO2 CH3CH2 H H OH CH(CO2CH2CH3)
B1047 CH2＝CHCH2 CH3CH2 H H OH CH(CO2CH2CH3)
B1048 HCCCH2 CH3CH2 H H OH CH(CO2CH2CH3)
B1049 CF3 CH3CH2 H H OH CH(CO2CH2CH3)
B1050 (CH3)2NSO2 CH3CH2 H H OH CH(CO2CH2CH3)
B1051 (CH3)2N CH3CH2 H H OH CH(CO2CH2CH3)
B1052 PhO CH3CH2 H H OH CH(CO2CH2CH3)
B1053 PhS CH3CH2 H H OH CH(CO2CH2CH3)
B1054 PhSO CH3CH2 H H OH CH(CO2CH2CH3)
B1055 PhSO2 CH3CH2 H H OH CH(CO2CH2CH3)
基团 R44 R37 R38 R39 R40 W
B1056 CN CH3CH2 H H OH CH(CO2CH2CH3)
B1057 CH3OCO H H H OH CHPh
B1058 H H H H OH CHPh
B1059 H H H H OH CH(CH2CH3)
B1060 H H H H OH CH(CH2CH2CH3)
B1061 H H H H OH CH(CH(CH3)2)
B1062 H H H H OH CH(C(CH3)3)
B1063 H H H H OH C(CH3)2
B1064 H H H H OH CH(CF3)
B1065 CH3OCO H H H OH C(CH3)(CF3)
B1066 H H H H OH C(CH3)(CF3)
B1067 CH3OCO CH3O H H OH CH2
B1068 H CH3O H H OH CH2
B1069 CH3O CH3OCO H CH3 OH CH2
B1070 CH3O H CH3 H OH CH2
B1071 Cl H H H OH CH2
B1072 F H H H OH CH2
B1073 H H H H OH CH(OCH3)2
B1074 H H H H OH CH2OSO2CH3
B1075 CH3 CH3 CH3 CH3 OH S(O)
B1076 ClCH2CH2 H H H OH CH2
B1077 HO(CH2)2 H H H OH CH2
B1078 MsO(CH2)2 H H H OH CH2
B1079 HOCH(CH3)CH2 H H H OH CH2
B1080 MsOCH(CH3)CH2 H H H OH CH2
B1081 (CH3)2CH H CH3 CH3 OH CH2
B1082 HCCCH2 H CH3 CH3 OH CH2
B1083 H2C＝CCH2 H CH3 CH3 OH CH2
在下表7中，Q是Q6
且Q6代表下列基团C：
表7：基团C：
基团 R84 R85 R86 R83 p W
C1 H H H OH 1 CH2
C2 CH3 H H OH 1 CH2
C3 CH3CH2 H H OH 1 CH2
C4 CH3CH2CH2 H H OH 1 CH2
C5 (CH3)2CH H H OH 1 CH2
C6 (CH3)3C H H OH 1 CH2
C7 CH3S H H OH 1 CH2
C8 CH3SO H H OH 1 CH2
C9 CH3SO2 H H OH 1 CH2
C10 Ph H H OH 1 CH2
C11 CH3O H H OH 1 CH2
C12 CH3OCO2 H H OH 1 CH2
C13 CH3CH2OCO2 H H OH 1 CH2
C14 CH2＝CHCH2 H H OH 1 CH2
C15 HCCCH2 H H OH 1 CH2
C16 CF3 H H OH 1 CH2
C17 (CH3)2NSO2 H H OH 1 CH2
C18 (CH3)2N H H OH 1 CH2
C19 PhO H H OH 1 CH2
C20 PhS H H OH 1 CH2
C21 PhSO H H OH 1 CH2
C22 PhSO2 H H OH 1 CH2
基团 R84 R85 R86 R83 p W
C23 CN H H OH 1 CH2
C24 CH3 CH3 H OH 1 CH2
C25 CH3CH2 CH3 H OH 1 CH2
C26 CH3CH2CH2 CH3 H OH 1 CH2
C27 (CH3)2CH CH3 H OH 1 CH2
C28 (CH3)3C CH3 H OH 1 CH2
C29 CH3S CH3 H OH 1 CH2
C30 CH3SO CH3 H OH 1 CH2
C31 CH3SO2 CH3 H OH 1 CH2
C32 Ph CH3 H OH 1 CH2
C33 CH3O CH3 H OH 1 CH2
C34 CH3OCO2 CH3 H OH 1 CH2
C35 CH3CH2OCO2 CH3 H OH 1 CH2
C36 CH2＝CHCH2 CH3 H OH 1 CH2
C37 HCCCH2 CH3 H OH 1 CH2
C38 CF3 CH3 H OH 1 CH2
C39 (CH3)2NSO2 CH3 H OH 1 CH2
C40 (CH3)2N CH3 H OH 1 CH2
C41 PhO CH3 H OH 1 CH2
C42 PhS CH3 H OH 1 CH2
C43 PhSO CH3 H OH 1 CH2
C44 PhSO2 CH3 H OH 1 CH2
C45 CN CH3 H OH 1 CH2
C46 H H H OH 4 CH2
C47 CH3 H H OH 4 CH2
C48 CH3CH2 H H OH 4 CH2
C49 CH3CH2CH2 H H OH 4 CH2
C50 (CH3)2CH H H OH 4 CH2
C51 (CH3)3C H H OH 4 CH2
C52 CH3S H H OH 4 CH2
C53 CH3SO H H OH 4 CH2
C54 CH3SO2 H H OH 4 CH2
C55 Ph H H OH 4 CH2
基团 R84 R85 R86 R83 p W
C56 CH3O H H OH 4 CH2
C57 CH3OCO2 H H OH 4 CH2
C58 CH3CH2OCO2 H H OH 4 CH2
C59 CH2＝CHCH2 H H OH 4 CH2
C60 HCCCH2 H H OH 4 CH2
C61 CF3 H H OH 4 CH2
C62 (CH3)2NSO2 H H OH 4 CH2
C63 (CH3)2N H H OH 4 CH2
C64 PhO H H OH 4 CH2
C65 PhS H H OH 4 CH2
C66 PhSO H H OH 4 CH2
C67 PhSO2 H H OH 4 CH2
C68 CN H H OH 4 CH2
C69 CH3 CH3 H OH 4 CH2
C70 CH3CH2 CH3 H OH 4 CH2
C71 CH3CH2CH2 CH3 H OH 4 CH2
C72 (CH3)2CH CH3 H OH 4 CH2
C73 (CH3)3C CH3 H OH 4 CH2
C74 CH3S CH3 H OH 4 CH2
C75 CH3SO CH3 H OH 4 CH2
C76 CH3SO2 CH3 H OH 4 CH2
C77 Ph CH3 H OH 4 CH2
C78 CH3O CH3 H OH 4 CH2
C79 CH3OCO2 CH3 H OH 4 CH2
C80 CH3CH2OCO2 CH3 H OH 4 CH2
C81 CH2＝CHCH2 CH3 H OH 4 CH2
C82 HCCCH2 CH3 H OH 4 CH2
C83 CF3 CH3 H OH 4 CH2
C84 (CH3)2NSO2 CH3 H OH 4 CH2
C85 (CH3)2N CH3 H OH 4 CH2
C86 PhO CH3 H OH 4 CH2
C87 PhS CH3 H OH 4 CH2
C88 PhSO CH3 H OH 4 CH2
基团 R84 R85 R86 R83 p W
C89 PhSO2 CH3 H OH 4 CH2
C90 CN CH3 H OH 4 CH2
C91 H H H OH 3 CH2
C92 CH3 H H OH 3 CH2
C93 CH3CH2 H H OH 3 CH2
C94 CH3CH2CH2 H H OH 3 CH2
C95 (CH3)2CH H H OH 3 CH2
C96 (CH3)3C H H OH 3 CH2
C97 CH3S H H OH 3 CH2
C98 CH3SO H H OH 3 CH2
C99 CH3SO2 H H OH 3 CH2
C100 Ph H H OH 3 CH2
C101 CH3O H H OH 3 CH2
C102 CH3OCO2 H H OH 3 CH2
C103 CH3CH2OCO2 H H OH 3 CH2
C104 CH2＝CHCH2 H H OH 3 CH2
C105 HCCCH2 H H OH 3 CH2
C106 CF3 H H OH 3 CH2
C107 (CH3)2NSO2 H H OH 3 CH2
C108 (CH3)2N H H OH 3 CH2
C109 PhO H H OH 3 CH2
C110 PhS H H OH 3 CH2
C111 PhSO H H OH 3 CH2
C112 PhSO2 H H OH 3 CH2
C113 CN H H OH 3 CH2
C114 CH3 CH3 H OH 3 CH2
C115 CH3CH2 CH3 H OH 3 CH2
C116 CH3CH2CH2 CH3 H OH 3 CH2
C117 (CH3)2CH CH3 H OH 3 CH2
C118 (CH3)3C CH3 H OH 3 CH2
C119 CH3S CH3 H OH 3 CH2
C120 CH3SO CH3 H OH 3 CH2
C121 CH3SO2 CH3 H OH 3 CH2
基团 R84 R85 R86 R83 p W
C122 Ph CH3 H OH 3 CH2
C123 CH3O CH3 H OH 3 CH2
C124 CH3OCO2 CH3 H OH 3 CH2
C125 CH3CH2OCO2 CH3 H OH 3 CH2
C126 CH2＝CHCH2 CH3 H OH 3 CH2
C127 HCCCH2 CH3 H OH 3 CH2
C128 CF3 CH3 H OH 3 CH2
C129 (CH3)2NSO2 CH3 H OH 3 CH2
C130 (CH3)2N CH3 H OH 3 CH2
C131 PhO CH3 H OH 3 CH2
C132 PhS CH3 H OH 3 CH2
C133 PhSO CH3 H OH 3 CH2
C134 PhSO2 CH3 H OH 3 CH2
C135 CN CH3 H OH 3 CH2
C136 CH3CH2 CH3CH2 H OH 1 CH2
C137 H H H OH 1 CH(CH3)
C138 CH3 H H OH 1 CH(CH3)
C139 CH3 CH3 H OH 1 CH(CH3)
C140 CH2CH3 H H OH 1 CH(CH3)
C141 CH2CH3 CH3 H OH 1 CH(CH3)
C142 CH3CH2 CH3CH2 H OH 1 CH(CH3)
C143 H H CH3 OH 1 CH2
C144 CH3 CH3 CH3 OH 1 CH2
C145 CH3CH2 CH3CH2 CH3 OH 1 CH2
C146 H H H OH 2 CH2
C147 CH3 CH3 H OH 2 CH2
C148 CH3CH2 CH3CH2 H OH 2 CH2
C149 H H H OH 5 CH2
C150 CH3 CH3 H OH 5 CH2
C151 CH3CH2 CH3CH2 H OH 5 CH2
在下表8中，Q是Q8
且Q8代表下列基团D：
表8：基团D：
基团 R88 R89 R90 R91 R87 o
D1 H H H H OH 2
D2 CH3 H H H OH 2
D3 CH3CH2 H H H OH 2
D4 CH3CH2CH2 H H H OH 2
D5 (CH3)2CH H H H OH 2
D6 (CH3)3C H H H OH 2
D7 CH3S H H H OH 2
D8 CH3SO H H H OH 2
D9 CH3SO2 H H H OH 2
D10 Ph H H H OH 2
D11 CH3O H H H OH 2
D12 CH2＝CHCH2 H H H OH 2
D13 HCCCH2 H H H OH 2
D14 CF3 H H H OH 2
D15 PhO H H H OH 2
D16 PhS H H H OH 2
D17 PhSO H H H OH 2
D18 PhSO2 H H H OH 2
D19 CH3 CH3 H H OH 2
D20 CH3CH2 CH3 H H OH 2
D21 CH3CH2CH2 CH3 H H OH 2
D22 (CH3)2CH CH3 H H OH 2
D23 (CH3)3C CH3 H H OH 2
基团 R88 R89 R90 R91 R87 o
D24 CH3S CH3 H H OH 2
D25 CH3SO CH3 H H OH 2
D26 CH3SO2 CH3 H H OH 2
D27 Ph CH3 H H OH 2
D28 CH3O CH3 H H OH 2
D29 CH2＝CHCH2 CH3 H H OH 2
D30 HCCCH2 CH3 H H OH 2
D31 CF3 CH3 H H OH 2
D32 PhO CH3 H H OH 2
D33 PhS CH3 H H OH 2
D34 PhSO CH3 H H OH 2
D35 PhSO2 CH3 H H OH 2
D36 H H H H OH 3
D37 CH3 H H H OH 3
D38 CH3CH2 H H H OH 3
D39 CH3CH2CH2 H H H OH 3
D40 (CH3)2CH H H H OH 3
D41 (CH3)3C H H H OH 3
D42 CH3S H H H OH 3
D43 CH3SO H H H OH 3
D44 CH3SO2 H H H OH 3
D45 Ph H H H OH 3
D46 CH3O H H H OH 3
D47 CH2＝CHCH2 H H H OH 3
D48 HCCCH2 H H H OH 3
D49 CF3 H H H OH 3
D50 PhO H H H OH 3
D51 PhS H H H OH 3
D52 PhSO H H H OH 3
D53 PhSO2 H H H OH 3
D54 CH3 CH3 H H OH 3
D55 CH3CH2 CH3 H H OH 3
D56 CH3CH2CH2 CH3 H H OH 3
基团 R88 R89 R90 R91 R87 o
D57 (CH3)2CH CH3 H H OH 3
D58 (CH3)3C CH3 H H OH 3
D59 CH3S CH3 H H OH 3
D60 CH3SO CH3 H H OH 3
D61 CH3SO2 CH3 H H OH 3
D62 Ph CH3 H H OH 3
D63 CH3O CH3 H H OH 3
D64 CH2＝CHCH2 CH3 H H OH 3
D65 HCCCH2 CH3 H H OH 3
D66 CF3 CH3 H H OH 3
D67 PhO CH3 H H OH 3
D68 PhS CH3 H H OH 3
D69 PhSO CH3 H H OH 3
D70 PhSO2 CH3 H H OH 3
D71 H H H H OH 4
D72 CH3 H H H OH 4
D73 CH3CH2 H H H OH 4
D74 CH3CH2CH2 H H H OH 4
D75 (CH3)2CH H H H OH 4
D76 (CH3)3C H H H OH 4
D77 CH3S H H H OH 4
D78 CH3SO H H H OH 4
D79 CH3SO2 H H H OH 4
D80 Ph H H H OH 4
D81 CH3O H H H OH 4
D82 CH2＝CHCH2 H H H OH 4
D83 HCCCH2 H H H OH 4
D84 CF3 H H H OH 4
D85 PhO H H H OH 4
D86 PhS H H H OH 4
D87 PhSO H H H OH 4
D88 PhSO2 H H H OH 4
D89 CH3 CH3 H H OH 4
基团 R88 R89 R90 R91 R87 o
D90 CH3CH2 CH3 H H OH 4
D91 CH3CH2CH2 CH3 H H OH 4
D92 (CH3)2CH CH3 H H OH 4
D93 (CH3)3C CH3 H H OH 4
D94 CH3S CH3 H H OH 4
D95 CH3SO CH3 H H OH 4
D96 CH3SO2 CH3 H H OH 4
D97 Ph CH3 H H OH 4
D98 CH3O CH3 H H OH 4
D99 CH2＝CHCH2 CH3 H H OH 4
D100 HCCCH2 CH3 H H OH 4
D101 CF3 CH3 H H OH 4
D102 PhO CH3 H H OH 4
D103 PhS CH3 H H OH 4
D104 PhSO CH3 H H OH 4
D105 PhSO2 CH3 H H OH 4
D106 H H H CH3 OH 4
D107 H H H CH3 OH 3
D108 H H H H OH 1
D109 CH3 H H H OH 1
D110 CH3OCO CH3 H H OH 1
D111 CH3CH2OCO CH3 H H OH 1
D112 CH3O CH3 H H OH 1
D113 CH3S CH3 H H OH 1
D114 CH3SO CH3 H H OH 1
D115 CH3SO2 CH3 H H OH 1
D116 CH3CH2 H H H OH 1
D117 CH3OCO CH3CH2 H H OH 1
D118 CH3CH2OCO CH3CH2 H H OH 1
D119 CH3O CH3CH2 H H OH 1
D120 CH3S CH3CH2 H H OH 1
D121 CH3SO CH3CH2 H H OH 1
D122 CH3SO2 CH3CH2 H H OH 1
基团 R88 R89 R90 R91 R87 o
D123 CH3CH2S CH3 H H OH 1
D124 CH3CH2SO CH3 H H OH 1
D125 CH3CH2SO2 CH3 H H OH 1
D126 CH3CH2S CH3CH2 H H OH 1
D127 CH3CH2SO CH3CH2 H H OH 1
D128 CH2CH2SO2 CH3CH2 H H OH 1
D129 H H CH3 H OH 1
D130 CH3 H CH3 H OH 1
D131 CH3OCO CH3 CH3 H OH 1
D132 CH3CH2OCO CH3 CH3 H OH 1
D133 CH3O CH3 CH3 H OH 1
D134 CH3S CH3 CH3 H OH 1
D135 CH3SO CH3 CH3 H OH 1
D136 CH3SO2 CH3 CH3 H OH 1
D137 H H H CH3 OH 1
D138 CH3 H H CH3 OH 1
D139 H H CH3 CH3 OH 1
D140 CH3CH2OCO CH3 H H OH 4
表9：式If化合物：
化合物. R92 R93 R94 R95 Q3
序号
A1 H H H CF3 B24
A2 CH3 H H CF3 B24
A3 CH3CH2 H H CF3 B24
化合物 R92 R93 R94 R95 Q3
序号
A4 (CH3)2CH H H CF3 B24
A5 (CH3)3C H H CF3 B24
A6 环丙基 H H CF3 B24
A7 CH3(CH2)2 H H CF3 B24
A8 CH3OCH2 H H CF3 B24
A9 CH3O(CH2)2 H H CF3 B24
A10 Ph H H CF3 B24
A11 PhO H H CF3 B24
A12 PhS H H CF3 B24
A13 PhSO H H CF3 B24
A14 PhSO2 H H CF3 B24
A15 CH3S H H CF3 B24
A16 CH3SO H H CF3 B24
A17 CF3 H H CF3 B24
A18 F2CH H H CF3 B24
A19 HCC H H CF3 B24
A20 CH3CC H H CF3 B24
A21 CH2＝CH H H CF3 B24
A22 CH2＝CHCH2 H H CF3 B24
A23 CH3SO2N(CH3) H H CF3 B24
A24 (CH3)2N H H CF3 B24
A25 (CH3)2NSO2 H H CF3 B24
A26 ClCH2 H H CF3 B24
A27 CH3SCH2 H H CF3 B24
A28 CH3SOCH2 H H CF3 B24
A29 CH3SO2CH2 H H CF3 B24
A30 [1，2，4]-三唑-1-基-甲基 H H CF3 B24
A31 CH3 CF3 H CH3 B24
A32 CH3 CH3 H CF3 B24
A33 H H H CF3CF2 B24
A34 CH3 H H CF3CF2 B24
A35 CH3CH2 H H CF3CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A36 环丙基 H H CF3CF2 B24
A37 (CH3)3C H H CF2CF2 B24
A38 (CH3)2CH H H CF3CF2 B24
A39 CH3(CH2)2 H H CF3CF2 B24
A40 CH3OCH2 H H CF3CF2 B24
A41 CH3O(CH2)2 H H CF3CF2 B24
A42 Ph H H CF3CF2 B24
A43 PhO H H CF3CF2 B24
A44 PhS H H CF3CF2 B24
A45 PhSO H H CF3CF2 B24
A46 PhSO2 H H CF3CF2 B24
A47 CH3S H H CF3CF2 B24
A48 CH3SO H H CF3CF2 B24
A49 CF3 H H CF3CF2 B24
A50 F2CH H H CF3CF2 B24
A51 HCC H H CF3CF2 B24
A52 CH3CC H H CF3CF2 B24
A53 CH2＝CH H H CF3CF2 B24
A54 CH2＝CHCH2 H H CF3CF2 B24
A55 CH3SO2N(CH3) H H CF3CF2 B24
A56 (CH3)2N H H CF3CF2 B24
A57 (CH3)2NSO2 H H CF3CF2 B24
A58 ClCH2 H H CF3CF2 B24
A59 CH3SCH2 H H CF3CF2 B24
A60 CH3SOCH2 H H CF3CF2 B24
A61 CH3SO2CH2 H H CF3CF2 B24
A62 [1，2，4]-三唑-1-基-甲基 H H CF3CF2 B24
A63 H H H CF3CF2CF2 B24
A64 CH3 H H CF3CF2CF2 B24
A65 CH3CH2 H H CF3CF2CF2 B24
A66 环丙基 H H CF3CF2CF2 B24
A67 (CH3)3C H H CF3CF2CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A68 (CH3)2CH H H CF3CF2CF2 B24
A69 CH3(CH2)2 H H CF3CF2CF2 B24
A70 CH3OCH2 H H CF3CF2CF2 B24
A71 CH3O(CH2)2 H H CF3CF2CF2 B24
A72 Ph H H CF3CF2CF2 B24
A73 PhO H H CF3CF2CF2 B24
A74 PhS H H CF3CF2CF2 B24
A75 PhSO H H CF3CF2CF2 B24
A76 PhSO2 H H CF3CF2CF2 B24
A77 CH3S H H CF3CF2CF2 B24
A78 CH3SO H H CF3CF2CF2 B24
A79 CF3 H H CF3CF2CF2 B24
A80 F2CH H H CF3CF2CF2 B24
A81 HCC H H CF3CF2CF2 B24
A82 CH3CC H H CF3CF2CF2 B24
A83 CH2＝CH H H CF3CF2CF2 B24
A84 CH2＝CHCH2 H H CF3CF2CF2 B24
A85 CH3SO2N(CH3) H H CF3CF2CF2 B24
A86 (CH3)2N H H CF3CF2CF2 B24
A87 (CH3)2NSO2 H H CF3CF2CF2 B24
A88 ClCH2 H H CF3CF2CF2 B24
A89 CH3SCH2 H H CF3CF2CF2 B24
A90 CH3SOCH2 H H CF3CF2CF2 B24
A91 CH3SO2CH2 H H CF3CF2CF2 B24
A92 [1，2，4]-三唑-1-基-甲基 H H CF3CF2CF2 B24
A93 H H H CF2Cl B24
A94 CH3 H H CF2Cl B24
A95 CH3CH2 H H CF2Cl B24
A96 环丙基 H H CF2Cl B24
A97 (CH3)3C H H CF2Cl B24
A98 (CH3)2CH H H CF2Cl B24
A99 CH3(CH2)2 H H CF2Cl B24
化合物 R92 R93 R94 R95 Q3
序号
A100 CH3OCH2 H H CF2Cl B24
A101 CH3O(CH2)2 H H CF2Cl B24
A102 Ph H H CF2Cl B24
A103 PhO H H CF2Cl B24
A104 PhS H H CF2Cl B24
A105 PhSO H H CF2Cl B24
A106 PhSO2 H H CF2Cl B24
A107 CH3S H H CF2Cl B24
A108 CH3SO H H CF2Cl B24
A109 CF3 H H CF2Cl B24
A110 F2CH H H CF2Cl B24
A111 HCC H H CF2Cl B24
A112 CH3CC H H CF2Cl B24
A113 CH2＝CH H H CF2Cl B24
A114 CH2＝CHCH2 H H CF2Cl B24
A115 CH3SO2N(CH3) H H CF2Cl B24
A116 (CH3)2N H H CF2Cl B24
A117 (CH3)2NSO2 H H CF2Cl B24
A118 ClCH2 H H CF2Cl B24
A119 CH3SCH2 H H CF2Cl B24
A120 CH3SOCH2 H H CF2Cl B24
A121 CH3SO2CH2 H H CF2Cl B24
A122 [1，2，4]-三唑-1-基-甲基 H H CF2Cl B24
A123 H H H CHF2 B24
A124 CH3 H H CHF2 B24
A125 CH3CH2 H H CHF2 B24
A126 环丙基 H H CHF2 B24
A127 (CH3)3C H H CHF2 B24
A128 (CH3)2CH H H CHF2 B24
A129 CH3(CH2)2 H H CHF2 B24
A130 CH3OCH2 H H CHF2 B24
A131 CH3O(CH2)2 H H CHF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A132 Ph H H CHF2 B24
A133 PhO H H CHF2 B24
A134 PhS H H CHF2 B24
A135 PhSO H H CHF2 B24
A136 PhSO2 H H CHF2 B24
A137 CH3S H H CHF2 B24
A138 CH3SO H H CHF2 B24
A139 CF3 H H CHF2 B24
A140 F2CH H H CHF2 B24
A141 HCC H H CHF2 B24
A142 CH3CC H H CHF2 B24
A143 CH2＝CH H H CHF2 B24
A144 CH2＝CHCH2 H H CHF2 B24
A145 CH3SO2N(CH3) H H CHF2 B24
A146 (CH3)2N H H CHF2 B24
A147 (CH3)2NSO2 H H CHF2 B24
A148 ClCH2 H H CHF2 B24
A149 CH3SCH2 H H CHF2 B24
A150 CH3SOCH2 H H CHF2 B24
A151 CH3SO2CH2 H H CHF2 B24
A152 [1，2，4]-三唑-1-基-甲基 H H CHF2 B24
A153 H H H CCl3 B24
A154 CH3 H H CCl3 B24
A155 CH3CH2 H H CCl3 B24
A156 环丙基 H H CCl3 B24
A157 (CH3)3C H H CCl3 B24
A158 (CH3)2CH H H CCl3 B24
A159 CH3(CH2)2 H H CCl3 B24
A160 CH3OCH2 H H CCl3 B24
A161 CH3O(CH2)2 H H CCl3 B24
A162 Ph H H CCl3 B24
A163 PhO H H CCl3 B24
化合物 R92 R93 R94 R95 Q3
序号
A164 PhS H H CCl3 B24
A165 PhSO H H CCl3 B24
A166 PhSO2 H H CCl3 B24
A167 CH3S H H CCl3 B24
A168 CH3SO H H CCl3 B24
A169 CF3 H H CCl3 B24
A170 F2CH H H CCl3 B24
A171 HCC H H CCl3 B24
A172 CH3CC H H CCl3 B24
A173 CH2＝CH H H CCl3 B24
A174 CH2＝CHCH2 H H CCl3 B24
A175 CH3SO2N(CH3) H H CCl3 B24
A176 (CH3)2N H H CCl3 B24
A177 (CH3)2NSO2 H H CCl3 B24
A178 ClCH2 H H CCl3 B24
A179 CH3SCH2 H H CCl3 B24
A180 CH3SOCH2 H H CCl3 B24
A181 CH3SO2CH2 H H CCl3 B24
A182 [1，2，4]-三唑-1-基-甲基 H H CCl3 B24
A183 H H CH3 CF3 B24
A184 CH3 H CH3 CF3 B24
A185 CH3CH2 H CH3 CF3 B24
A186 环丙基 H CH3 CF3 B24
A187 (CH3)3C H CH3 CF3 B24
A188 (CH3)2CH H CH3 CF3 B24
A189 CH3(CH2)2 H CH3 CF3 B24
A190 CH3OCH2 H CH3 CF3 B24
A191 CH3O(CH2)2 H CH3 CF3 B24
A192 Ph H CH3 CF3 B24
A193 PhO H CH3 CF3 B24
A194 PhS H CH3 CF3 B24
A195 PhSO H CH3 CF3 B24
化合物 R92 R93 R94 R95 Q3
序号
A196 PhSO2 H CH3 CF3 B24
A197 CH3S H CH3 CF3 B24
A198 CH3SO H CH3 CF3 B24
A199 CF3 H CH3 CF3 B24
A200 F2CH H CH3 CF3 B24
A201 HCC H CH3 CF3 B24
A202 CH3CC H CH3 CF3 B24
A203 CH2＝CH H CH3 CF3 B24
A204 CH2＝CHCH2 H CH3 CF3 B24
A205 CH3SO2N(CH3) H CH3 CF3 B24
A206 (CH3)2N H CH3 CF3 B24
A207 (CH3)2NSO2 H CH3 CF3 B24
A208 ClCH2 H CH3 CF3 B24
A209 CH3SCH2 H CH3 CF3 B24
A210 CH3SOCH2 H CH3 CF3 B24
A211 CH3SO2CH2 H CH3 CF3 B24
A212 H H CH3 CF3CF2 B24
A213 CH3 H CH3 CF3CF2 B24
A214 CH3CH2 H CH3 CF3CF2 B24
A215 环丙基 H CH3 CF3CF2 B24
A216 (CH3)3C H CH3 CF3CF2 B24
A217 (CH3)2CH H CH3 CF3CF2 B24
A218 CH3(CH2)2 H CH3 CF3CF2 B24
A219 CH3OCH2 H CH3 CF3CF2 B24
A220 CH3O(CH2)2 H CH3 CF3CF2 B24
A221 Ph H CH3 CF3CF2 B24
A222 PhO H CH3 CF3CF2 B24
A223 PhS H CH3 CF3CF2 B24
A224 PhSO H CH3 CF3CF2 B24
A225 PhSO2 H CH3 CF3CF2 B24
A226 CH3S H CH3 CF3CF2 B24
A227 CH3SO H CH3 CF3CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A228 CF3 H CH3 CF3CF2 B24
A229 F2CH H CH3 CF3CF2 B24
A230 HCC H CH3 CF3CF2 B24
A231 CH3CC H CH3 CF3CF2 B24
A232 CH2＝CH H CH3 CF3CF2 B24
A233 CH2＝CHCH2 H CH3 CF3CF2 B24
A234 CH3SO2N(CH3) H CH3 CF3CF2 B24
A235 (CH3)2N H CH3 CF3CF2 B24
A236 (CH3)2NSO2 H CH3 CF3CF2 B24
A237 ClCH2 H CH3 CF3CF2 B24
A238 CH3SCH2 H CH3 CF3CF2 B24
A239 CH3SOCH2 H CH3 CF3CF2 B24
A240 CH3SO2CH2 H CH3 CF3CF2 B24
A241 H H CH3 CF3CF2CF2 B24
A242 CH3 H CH3 CF3CF2CF2 B24
A243 CH3CH2 H CH3 CF3CF2CF2 B24
A244 环丙基 H CH3 CF3CF2CF2 B24
A245 (CH3)3C H CH3 CF3CF2CF2 B24
A246 (CH3)2CH H CH3 CF3CF2CF2 B24
A247 CH3(CH2)2 H CH3 CF3CF2CF2 B24
A248 CH3OCH2 H CH3 CF3CF2CF2 B24
A249 CH3O(CH2)2 H CH3 CF3CF2CF2 B24
A250 Ph H CH3 CF3CF2CF2 B24
A251 PhO H CH3 CF3CF2CF2 B24
A252 PhS H CH3 CF3CF2CF2 B24
A253 PhSO H CH3 CF3CF2CF2 B24
A254 PhSO2 H CH3 CF3CF2CF2 B24
A255 CH3S H CH3 CF3CF2CF2 B24
A256 CH3SO H CH3 CF3CF2CF2 B24
A257 CF3 H CH3 CF3CF2CF2 B24
A258 F2CH H CH3 CF3CF2CF2 B24
A259 HCC H CH3 CF3CF2CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A260 CH3CC H CH3 CF3CF2CF2 B24
A261 CH2＝CH H CH3 CF3CF2CF2 B24
A262 CH2＝CHCH2 H CH3 CF3CF2CF2 B24
A263 CH3SO2N(CH3) H CH3 CF3CF2CF2 B24
A264 (CH3)2N H CH3 CF3CF2CF2 B24
A265 (CH3)2NSO2 H CH3 CF3CF2CF2 B24
A266 ClCH2 H CH3 CF3CF2CF2 B24
A267 CH3SCH2 H CH3 CF3CF2CF2 B24
A268 CH3SOCH2 H CH3 CF3CF2CF2 B24
A269 CH3SO2CH2 H CH3 CF3CF2CF2 B24
A270 H H CH3 CF2Cl B24
A271 CH3 H CH3 CF2Cl B24
A272 CH3CH2 H CH3 CF2Cl B24
A273 环丙基 H CH3 CF2Cl B24
A274 (CH3)3C H CH3 CF2Cl B24
A275 (CH3)2CH H CH3 CF2Cl B24
A276 CH3(CH2)2 H CH3 CF2Cl B24
A277 CH3OCH2 H CH3 CF2Cl B24
A278 CH3O(CH2)2 H CH3 CF2Cl B24
A279 Ph H CH3 CF2Cl B24
A280 PhO H CH3 CF2Cl B24
A281 PhS H CH3 CF2Cl B24
A282 PhSO H CH3 CF2Cl B24
A283 PhSO2 H CH3 CF2Cl B24
A284 CH3S H CH3 CF2Cl B24
A285 CH3SO H CH3 CF2Cl B24
A286 CF3 H CH3 CF2Cl B24
A287 F2CH H CH3 CF2Cl B24
A288 HCC H CH3 CF2Cl B24
A289 CH3CC H CH3 CF2Cl B24
A290 CH2＝CH H CH3 CF2Cl B24
A291 CH2＝CHCH2 H CH3 CF2Cl B24
化合物 R92 R93 R94 R95 Q3
序号
A292 CH3SO2N(CH3) H CH3 CF2Cl B24
A293 (CH3)2N H CH3 CF2Cl B24
A294 (CH3)2NSO2 H CH3 CF2Cl B24
A295 ClCH2 H CH3 CF2Cl B24
A296 CH3SCH2 H CH3 CF2Cl B24
A297 CH3SOCH2 H CH3 CF2Cl B24
A298 CH3SO2CH2 H CH3 CF2Cl B24
A299 H H CH3 CHF2 B24
A300 CH3 H CH3 CHF2 B24
A301 CH3CH2 H CH3 CHF2 B24
A302 环丙基 H CH3 CHF2 B24
A303 (CH3)3C H CH3 CHF2 B24
A304 (CH3)2CH H CH3 CHF2 B24
A305 CH3(CH2)2 H CH3 CHF2 B24
A306 CH3OCH2 H CH3 CHF2 B24
A307 CH3O(CH2)2 H CH3 CHF2 B24
A308 Ph H CH3 CHF2 B24
A309 PhO H CH3 CHF2 B24
A310 PhS H CH3 CHF2 B24
A311 PhSO H CH3 CHF2 B24
A312 PhSO2 H CH3 CHF2 B24
A313 CH3S H CH3 CHF2 B24
A314 CH3SO H CH3 CHF2 B24
A315 CF3 H CH3 CHF2 B24
A316 F2CH H CH3 CHF2 B24
A317 HCC H CH3 CHF2 B24
A318 CH3CC H CH3 CHF2 B24
A319 CH2＝CH H CH3 CHF2 B24
A320 CH2＝CHCH2 H CH3 CHF2 B24
A321 CH3SO2N(CH3) H CH3 CHF2 B24
A322 (CH3)2N H CH3 CHF2 B24
A323 (CH3)2NSO2 H CH3 CHF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A324 ClCH2 H CH3 CHF2 B24
A325 CH3SCH2 H CH3 CHF2 B24
A326 CH3SOCH2 H CH3 CHF2 B24
A327 CH3SO2CH2 H CH3 CHF2 B24
A328 H H CH3 CCl3 B24
A329 CH3 H CH3 CCl3 B24
A330 CH3CH2 H CH3 CCl3 B24
A331 (CH3)3C H CH3 CCl3 B24
A332 (CH3)2CH H CH3 CCl3 B24
A333 环丙基 H CH3 CCl3 B24
A334 CH3(CH2)2 H CH3 CCl3 B24
A335 CH3OCH2 H CH3 CCl3 B24
A336 CH3O(CH2)2 H CH3 CCl3 B24
A337 Ph H CH3 CCl3 B24
A338 PhO H CH3 CCl3 B24
A339 PhS H CH3 CCl3 B24
A340 PhSO H CH3 CCl3 B24
A341 PhSO2 H CH3 CCl3 B24
A342 CH3S H CH3 CCl3 B24
A343 CH3SO H CH3 CCl3 B24
A344 CF3 H CH3 CCl3 B24
A345 F2CH H CH3 CCl3 B24
A346 HCC H CH3 CCl3 B24
A347 CH3CC H CH3 CCl3 B24
A348 CH2＝CH H CH3 CCl3 B24
A349 CH2＝CHCH2 H CH3 CCl3 B24
A350 CH3SO2N(CH3) H CH3 CCl3 B24
A351 (CH3)2N H CH3 CCl3 B24
A352 (CH3)2NSO2 H CH3 CCl3 B24
A353 ClCH2 H CH3 CCl3 B24
A354 CH3SCH2 H CH3 CCl3 B24
A355 CH3SOCH2 H CH3 CCl3 B24
化合物 R92 R93 R94 R95 Q3
序号
A356 CH3SO2CH2 H CH3 CCl3 B24
A357 H H Ph CF3 B24
A358 CH3 H Ph CF3 B24
A359 CH3CH2 H Ph CF3 B24
A360 环丙基 H Ph CF3 B24
A361 (CH3)3C H Ph CF3 B24
A362 (CH3)2CH H Ph CF3 B24
A363 CH3(CH2)2 H Ph CF3 B24
A364 CH3OCH2 H Ph CF3 B24
A365 CH3O(CH2)2 H Ph CF3 B24
A366 Ph H Ph CF3 B24
A367 PhO H Ph CF3 B24
A368 PhS H Ph CF3 B24
A369 PhSO H Ph CF3 B24
A370 PhSO2 H Ph CF3 B24
A371 CH3S H Ph CF3 B24
A372 CH3SO H Ph CF3 B24
A373 CF3 H Ph CF3 B24
A374 F2CH H Ph CF3 B24
A375 HCC H Ph CF3 B24
A376 CH3CC H Ph CF3 B24
A377 CH2＝CH H Ph CF3 B24
A378 CH2＝CHCH2 H Ph CF3 B24
A379 CH3SO2N(CH3) H Ph CF3 B24
A380 (CH3)2N H Ph CF3 B24
A381 (CH3)2NSO2 H Ph CF3 B24
A382 ClCH2 H Ph CF3 B24
A383 CH3SCH2 H Ph CF3 B24
A384 CH3SOCH2 H Ph CF3 B24
A385 CH3SO2CH2 H Ph CF3 B24
A386 H H Ph CF3CF2 B24
A387 CH3 H Ph CF3CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A388 CH3CH2 H Ph CF3CF2 B24
A389 环丙基 H Ph CF3CF2 B24
A390 (CH3)3C H Ph CF3CF2 B24
A391 (CH3)2CH H Ph CF3CF2 B24
A392 CH3(CH2)2 H Ph CF3CF2 B24
A393 CH3OCH2 H Ph CF3CF2 B24
A394 CH3O(CH2)2 H Ph CF3CF2 B24
A395 Ph H Ph CF3CF2 B24
A396 PhO H Ph CF3CF2 B24
A397 PhS H Ph CF3CF2 B24
A398 PhSO H Ph CF3CF2 B24
A399 PhSO2 H Ph CF3CF2 B24
A400 CH3S H Ph CF3CF2 B24
A401 CH3SO H Ph CF3CF2 B24
A402 CF3 H Ph CF3CF2 B24
A403 F2CH H Ph CF3CF2 B24
A404 HCC H Ph CF3CF2 B24
A405 CH3CC H Ph CF3CF2 B24
A406 CH2＝CH H Ph CF3CF2 B24
A407 CH2＝CHCH2 H Ph CF3CF2 B24
A408 CH3SO2N(CH3) H Ph CF3CF2 B24
A409 (CH3)2N H Ph CF3CF2 B24
A410 (CH3)2NSO2 H Ph CF3CF2 B24
A411 ClCH2 H Ph CF3CF2 B24
A412 CH3SCH2 H Ph CF3CF2 B24
A413 CH3SOCH2 H Ph CF3CF2 B24
A414 CH3S02CH2 H Ph CF3CF2 B24
A415 H H Ph CF3CF2CF2 B24
A416 CH3 H Ph CF3CF2CF2 B24
A417 CH3CH2 H Ph CF3CF2CF2 B24
A418 环丙基 H Ph CF3CF2CF2 B24
A419 (CH3)3C H Ph CF3CF2CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A420 (CH3)2CH H Ph CF3CF2CF2 B24
A421 CH3(CH2)2 H Ph CF3CF2CF2 B24
A422 CH3OCH2 H Ph CF3CF2CF2 B24
A423 CH3O(CH2)2 H Ph CF3CF2CF2 B24
A424 Ph H Ph CF3CF2CF2 B24
A425 PhO H Ph CF3CF2CF2 B24
A426 PhS H Ph CF3CF2CF2 B24
A427 PhSO H Ph CF3CF2CF2 B24
A428 PhSO2 H Ph CF3CF2CF2 B24
A429 CH3S H Ph CF3CF2CF2 B24
A430 CH3SO H Ph CF3CF2CF2 B24
A431 CF3 H Ph CF3CF2CF2 B24
A432 F2CH H Ph CF3CF2CF2 B24
A433 HCC H Ph CF3CF2CF2 B24
A434 CH3CC H Ph CF3CF2CF2 B24
A435 CH2＝CH H Ph CF3CF2CF2 B24
A436 CH2＝CHCH2 H Ph CF3CF2CF2 B24
A437 CH3SO2N(CH3) H Ph CF3CF2CF2 B24
A438 (CH3)2N H Ph CF3CF2CF2 B24
A439 (CH3)2NSO2 H Ph CF3CF2CF2 B24
A440 ClCH2 H Ph CF3CF2CF2 B24
A441 CH3SCH2 H Ph CF3CF2CF2 B24
A442 CH3SOCH2 H Ph CF3CF2CF2 B24
A443 CH3SO2CH2 H Ph CF3CF2CF2 B24
A444 H H Ph CF2Cl B24
A445 CH3 H Ph CF2Cl B24
A446 CH3CH2 H Ph CF2Cl B24
A447 环丙基 H Ph CF2Cl B24
A448 (CH3)3C H Ph CF2Cl B24
A449 (CH3)2CH H Ph CF2Cl B24
A450 CH3(CH2)2 H Ph CF2Cl B24
A451 CH3OCH2 H Ph CF2Cl B24
化合物 R92 R93 R94 R95 Q3
序号
A452 CH3O(CH2)2 H Ph CF2Cl B24
A453 Ph H Ph CF2Cl B24
A454 PhO H Ph CF2Cl B24
A455 PhS H Ph CF2Cl B24
A456 PhSO H Ph CF2Cl B24
A457 PhSO2 H Ph CF2Cl B24
A458 CH3S H Ph CF2Cl B24
A459 CH3SO H Ph CF2Cl B24
A460 CF3 H Ph CF2Cl B24
A461 F2CH H Ph CF2Cl B24
A462 HCC H Ph CF2Cl B24
A463 CH3CC H Ph CF2Cl B24
A464 CH2＝CH H Ph CF2Cl B24
A465 CH2＝CHCH2 H Ph CF2Cl B24
A466 CH3SO2N(CH3) H Ph CF2Cl B24
A467 (CH3)2N H Ph CF2Cl B24
A468 (CH3)2NSO2 H Ph CF2Cl B24
A469 ClCH2 H Ph CF2Cl B24
A470 CH3SCH2 H Ph CF2Cl B24
A471 CH3SOCH2 H Ph CF2Cl B24
A472 CH3SO2CH2 H Ph CF2Cl B24
A473 H H Ph CHF2 B24
A474 CH3 H Ph CHF2 B24
A475 CH3CH2 H Ph CHF2 B24
A476 环丙基 H Ph CHF2 B24
A477 (CH3)3C H Ph CHF2 B24
A478 (CH3)2CH H Ph CHF2 B24
A479 CH3(CH2)2 H Ph CHF2 B24
A480 CH3OCH2 H Ph CHF2 B24
A481 CH3O(CH2)2 H Ph CHF2 B24
A482 Ph H Ph CHF2 B24
A483 PhO H Ph CHF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A484 PhS H Ph CHF2 B24
A485 PhSO H Ph CHF2 B24
A486 PhSO2 H Ph CHF2 B24
A487 CH3S H Ph CHF2 B24
A488 CH3SO H Ph CHF2 B24
A489 CF3 H Ph CHF2 B24
A490 F2CH H Ph CHF2 B24
A491 HCC H Ph CHF2 B24
A492 CH3CC H Ph CHF2 B24
A493 CH2＝CH H Ph CHF2 B24
A494 CH2＝CHCH2 H Ph CHF2 B24
A495 CH3SO2N(CH3) H Ph CHF2 B24
A496 (CH3)2N H Ph CHF2 B24
A497 (CH3)2NSO2 H Ph CHF2 B24
A498 ClCH2 H Ph CHF2 B24
A499 CH3SCH2 H Ph CHF2 B24
A500 CH3SOCH2 H Ph CHF2 B24
A501 CH3SO2CH2 H Ph CHF2 B24
A502 H H Ph CCl3 B24
A503 CH3 H Ph CCl3 B24
A504 CH3CH2 H Ph CCl3 B24
A505 环丙基 H Ph CCl3 B24
A506 (CH3)3C H Ph CCl3 B24
A507 (CH3)2CH H Ph CCl3 B24
A508 CH3(CH2)2 H Ph CCl3 B24
A509 CH3OCH2 H Ph CCl3 B24
A510 CH3O(CH2)2 H Ph CCl3 B24
A511 Ph H Ph CCl3 B24
A512 PhO H Ph CCl3 B24
A513 PhS H Ph CCl3 B24
A514 PhSO H Ph CCl3 B24
A515 PhSO2 H Ph CCl3 B24
化合物 R92 R93 R94 R95 Q3
序号
A516 CH3S H Ph CCl3 B24
A517 CH3SO H Ph CCl3 B24
A518 CF3 H Ph CCl3 B24
A519 F2CH H Ph CCl3 B24
A520 HCC H Ph CCl3 B24
A521 CH3CC H Ph CCl3 B24
A522 CH2＝CH H Ph CCl3 B24
A523 CH2＝CHCH2 H Ph CCl3 B24
A524 CH3SO2N(CH3) H Ph CCl3 B24
A525 (CH3)2N H Ph CCl3 B24
A526 (CH3)2NSO2 H Ph CCl3 B24
A527 ClCH2 H Ph CCl3 B24
A528 CH3SCH2 H Ph CCl3 B24
A529 CH3SOCH2 H Ph CCl3 B24
A530 CH3SO2CH2 H Ph CCl3 B24
A531 H CH3 H CF3 B24
A532 H CH3CH2 H CF3 B24
A533 H 环丙基 H CF3 B24
A534 H (CH3)3CH H CF3 B24
A535 H (CH3)2CH H CF3 B24
A536 H CH3(CH2)2 H CF3 B24
A537 H CH3OCH2 H CF3 B24
A538 H CH3O(CH2)2 H CF3 B24
A539 H Ph H CF3 B24
A540 H PhO H CF3 B24
A541 H PhS H CF3 B24
A542 H PhSO H CF3 B24
A543 H PhSO2 H CF3 B24
A544 H CH3S H CF3 B24
A545 H CH3SO H CF3 B24
A546 H CF3 H CF3 B24
A547 H F2CH H CF3 B24
化合物 R92 R93 R94 R95 Q3
序号
A548 H HCC H CF3 B24
A549 H CH3CC H CF3 B24
A550 H CH2＝CH H CF3 B24
A551 H CH2＝CHCH2 H CF3 B24
A552 H CH3SO2N(CH3) H CF3 B24
A553 H (CH3)2N H CF3 B24
A554 H (CH3)2NSO2 H CF3 B24
A555 H CH3SCH2 H CF3 B24
A556 H CH3SOCH2 H CF3 B24
A557 H CH3SO2CH2 H CF3 B24
A558 H CH3 H CF3CF2 B24
A559 H CH3CH2 H CF3CF2 B24
A560 H 环丙基 H CF3CF2 B24
A561 H (CH3)3C H CF3CF2 B24
A562 H (CH3)2CH H CF3CF2 B24
A563 H CH3(CH2)2 H CF3CF2 B24
A564 H CH3OCH2 H CF3CF2 B24
A565 H CH3O(CH2)2 H CF3CF2 B24
A566 H Ph H CF3CF2 B24
A567 H PhO H CF3CF2 B24
A568 H PhS H CF3CF2 B24
A569 H PhSO H CF3CF2 B24
A570 H PhSO2 H CF3CF2 B24
A571 H CH3S H CF3CF2 B24
A572 H CH3SO H CF3CF2 B24
A573 H CF3 H CF3CF2 B24
A574 H F2CH H CF3CF2 B24
A575 H HCC H CF3CF2 B24
A576 H CH3CC H CF3CF2 B24
A577 H CH2＝CH H CF3CF2 B24
A578 H CH2＝CHCH2 H CF3CF2 B24
A579 H CH3SO2N(CH3) H CF3CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A580 H (CH3)2N H CF3CF2 B24
A581 H (CH3)2NSO2 H CF3CF2 B24
A582 H CH3SCH2 H CF3CF2 B24
A583 H CH3SOCH2 H CF3CF2 B24
A584 H CH3SO2CH2 H CF3CF2 B24
A585 H CH3 H CF3CF2CF2 B24
A586 H CH3CH2 H CF3CF2CF2 B24
A587 H 环丙基 H CF3CF2CF2 B24
A588 H (CH3)3C H CF3CF2CF2 B24
A589 H (CH3)2CH H CF3CF2CF2 B24
A590 H CH3(CH2)2 H CF3CF2CF2 B24
A591 H CH3OCH2 H CF3CF2CF2 B24
A592 H CH3O(CH2)2 H CF3CF2CF2 B24
A593 H Ph H CF3CF2CF2 B24
A594 H PhO H CF3CF2CF2 B24
A595 H PhS H CF3CF2CF2 B24
A596 H PhSO H CF3CF2CF2 B24
A597 H PhSO2 H CF3CF2CF2 B24
A598 H CH3S H CF3CF2CF2 B24
A599 H CH3SO H CF3CF2CF2 B24
A600 H CF3 H CF3CF2CF2 B24
A601 H F2CH H CF3CF2CF2 B24
A602 H HCC H CF3CF2CF2 B24
A603 H CH3CC H CF3CF2CF2 B24
A604 H CH2＝CH H CF3CF2CF2 B24
A605 H CH2＝CHCH2 H CF3CF2CF2 B24
A606 H CH3SO2N(CH3) H CF3CF2CF2 B24
A607 H (CH3)2N H CF3CF2CF2 B24
A608 H (CH3)2NSO2 H CF3CF2CF2 B24
A609 H CH3SCH2 H CF3CF2CF2 B24
A610 H CH3SOCH2 H CF3CF2CF2 B24
A611 H CH3SO2CH2 H CF3CF2CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A612 H CH3 H CF2Cl B24
A613 H CH3CH2 H CF2Cl B24
A614 H 环丙基 H CF2Cl B24
A615 H (CH3)3C H CF2Cl B24
A616 H (CH3)2CH H CF2Cl B24
A617 H CH3(CH2)2 H CF2Cl B24
A618 H CH3OCH2 H CF2Cl B24
A619 H CH3O(CH2)2 H CF2Cl B24
A620 H Ph H CF2Cl B24
A621 H PhO H CF2Cl B24
A622 H PhS H CF2Cl B24
A623 H PhSO H CF2Cl B24
A624 H PhSO2 H CF2Cl B24
A625 H CH3S H CF2Cl B24
A626 H CH3SO H CF2Cl B24
A627 H CF3 H CF2Cl B24
A628 H F2CH H CF2Cl B24
A629 H HCC H CF2Cl B24
A630 H CH3CC H CF2Cl B24
A631 H CH2＝CH H CF2Cl B24
A632 H CH2＝CHCH2 H CF2Cl B24
A633 H CH3SO2N(CH3) H CF2Cl B24
A634 H (CH3)2N H CF2Cl B24
A635 H (CH3)2NSO2 H CF2Cl B24
A636 H CH3SCH2 H CF2Cl B24
A637 H CH3SOCH2 H CF2Cl B24
A638 H CH3SO2CH2 H CF2Cl B24
A639 H CH3 H CHF2 B24
A640 H CH3CH2 H CHF2 B24
A641 H 环丙基 H CHF2 B24
A642 H (CH3)3C H CHF2 B24
A643 H (CH3)2CH H CHF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A644 H CH3(CH2)2 H CHF2 B24
A645 H CH3OCH2 H CHF2 B24
A646 H CH3O(CH2)2 H CHF2 B24
A647 H Ph H CHF2 B24
A648 H PhO H CHF2 B24
A649 H PhS H CHF2 B24
A650 H PhSO H CHF2 B24
A651 H PhSO2 H CHF2 B24
A652 H CH3S H CHF2 B24
A653 H CH3SO H CHF2 B24
A654 H CF3 H CHF2 B24
A655 H F2CH H CHF2 B24
A656 H HCC H CHF2 B24
A657 H CH3CC H CHF2 B24
A658 H CH2＝CH H CHF2 B24
A659 H CH2＝CHCH2 H CHF2 B24
A660 H CH3SO2N(CH3) H CHF2 B24
A661 H (CH3)2N H CHF2 B24
A662 H (CH3)2NSO2 H CHF2 B24
A663 H CH3SCH2 H CHF2 B24
A664 H CH3SOCH2 H CHF2 B24
A665 H CH3SO2CH2 H CHF2 B24
A666 H CH3 H CCl3 B24
A667 H CH3CH2 H CCl3 B24
A668 H 环丙基 H CCl3 B24
A669 H (CH3)3C H CCl3 B24
A670 H (CH3)2CH H CCl3 B24
A671 H CH3(CH2)2 H CCl3 B24
A672 H CH3OCH2 H CCl3 B24
A673 H CH3O(CH2)2 H CCl3 B24
A674 H Ph H CCl3 B24
A675 H PhO H CCL3 B24
化合物 R92 R93 R94 R95 Q3
序号
A676 H PhS H CCl3 B24
A677 H PhSO H CCl3 B24
A678 H PhSO2 H CCl3 B24
A679 H CH3S H CCl3 B24
A680 H CH3SO H CCl3 B24
A681 H CF3 H CCl3 B24
A682 H F2CH H CCl3 B24
A683 H HCC H CCl3 B24
A684 H CH3CC H CCl3 B24
A685 H CH2＝CH H CCl3 B24
A686 H CH2＝CHCH2 H CCl3 B24
A687 H CH3SO2N(CH3) H CCl3 B24
A688 H (CH3)2N H CCl3 B24
A689 H (CH3)2NSO2 H CCl3 B24
A690 H CH3SCH2 H CCl3 B24
A691 H CH3SOCH2 H CCl3 B24
A692 H CH3SO2CH2 H CCl3 B24
A693 H CH3 CH3 CF3 B24
A694 H CH3CH2 CH3 CF3 B24
A695 H 环丙基 CH3 CF3 B24
A696 H (CH3)3C CH3 CF3 B24
A697 H (CH3)2CH CH3 CF3 B24
A698 H CH3(CH2)2 CH3 CF3 B24
A699 H CH3OCH2 CH3 CF3 B24
A700 H CH3O(CH2)2 CH3 CF3 B24
A701 H Ph CH3 CF3 B24
A702 H PhO CH3 CF3 B24
A703 H PhS CH3 CF3 B24
A704 H PhSO CH3 CF3 B24
A705 H PhSO2 CH3 CF3 B24
A706 H CH3S CH3 CF3 B24
A707 H CH3SO CH3 CF3 B24
化合物 R92 R93 R94 R95 Q3
序号
A708 H CF3 CH3 CF3 B24
A709 H F2CH CH3 CF3 B24
A710 H HCC CH3 CF3 B24
A711 H CH3CC CH3 CF3 B24
A712 H CH2＝CH CH3 CF3 B24
A713 H CH2＝CHCH2 CH3 CF3 B24
A714 H CH3SO2N(CH3) CH3 CF3 B24
A715 H (CH3)2N CH3 CF3 B24
A716 H (CH3)2NSO2 CH3 CF3 B24
A717 H CH3SCH2 CH3 CF3 B24
A718 H CH3SOCH2 CH3 CF3 B24
A719 H CH3SO2CH2 CH3 CF3 B24
A720 H CH3 CH3 CF3CF2 B24
A721 H CH3CH2 CH3 CF3CF2 B24
A722 H 环丙基 CH3 CF3CF2 B24
A723 H (CH3)3C CH3 CF3CF2 B24
A724 H (CH3)2CH CH3 CF3CF2 B24
A725 H CH3(CH2)2 CH3 CF3CF2 B24
A726 H CH3OCH2 CH3 CF3CF2 B24
A727 H CH3O(CH2)2 CH3 CF3CF2 B24
A728 H Ph CH3 CF3CF2 B24
A729 H PhO CH3 CF3CF2 B24
A730 H PhS CH3 CF3CF2 B24
A731 H PhSO CH3 CF3CF2 B24
A732 H PhSO2 CH3 CF3CF2 B24
A733 H CH3S CH3 CF3CF2 B24
A734 H CH3SO CH3 CF3CF2 B24
A735 H CF3 CH3 CF3CF2 B24
A736 H F2CH CH3 CF3CF2 B24
A737 H HCC CH3 CF3CF2 B24
A738 H CH3CC CH3 CF3CF2 B24
A739 H CH2＝CH CH3 CF3CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A740 H CH2＝CHCH2 CH3 CF3CF2 B24
A741 H CH3SO2N(CH3) CH3 CF3CF2 B24
A742 H (CH3)2N CH3 CF3CF2 B24
A743 H (CH3)2NSO2 CH3 CF3CF2 B24
A744 H CH3SCH2 CH3 CF3CF2 B24
A745 H CH3SOCH2 CH3 CF3CF2 B24
A746 H CH3SO2CH2 CH3 CF3CF2 B24
A747 H CH3 CH3 CF3CF2CF2 B24
A748 H CH3CH2 CH3 CF3CF2CF2 B24
A749 H 环丙基 CH3 CF3CF2CF2 B24
A750 H (CH3)3C CH3 CF3CF2CF2 B24
A751 H (CH3)2CH CH3 CF3CF2CF2 B24
A752 H CH3(CH2)2 CH3 CF3CF2CF2 B24
A753 H CH3OCH2 CH3 CF3CF2CF2 B24
A754 H CH3O(CH2)2 CH3 CF3CF2CF2 B24
A755 H Ph CH3 CF3CF2CF2 B24
A756 H PhO CH3 CF3CF2CF2 B24
A757 H PhS CH3 CF3CF2CF2 B24
A758 H PhSO CH3 CF3CF2CF2 B24
A759 H PhSO2 CH3 CF3CF2CF2 B24
A760 H CH3S CH3 CF3CF2CF2 B24
A761 H CH3SO CH3 CF3CF2CF2 B24
A762 H CF3 CH3 CF3CF2CF2 B24
A763 H F2CH CH3 CF3CF2CF2 B24
A764 H HCC CH3 CF3CF2CF2 B24
A765 H CH3CC CH3 CF3CF2CF2 B24
A766 H CH2＝CH CH3 CF3CF2CF2 B24
A767 H CH2＝CHCH2 CH3 CF3CF2CF2 B24
A768 H CH3SO2N(CH3) CH3 CF3CF2CF2 B24
A769 H (CH3)2N CH3 CF3CF2CF2 B24
A770 H (CH3)2NSO2 CH3 CF3CF2CF2 B24
A771 H CH3SCH2 CH3 CF3CF2CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A772 H CH3SOCH2 CH3 CF3CF2CF2 B24
A773 H CH3SO2CH2 CH3 CF3CF2CF2 B24
A774 H CH3 CH3 CF2Cl B24
A775 H CH3CH2 CH3 CF2Cl B24
A776 H 环丙基 CH3 CF2Cl B24
A777 H (CH3)3C CH3 CF2Cl B24
A778 H (CH3)2CH CH3 CF2Cl B24
A779 H CH3(CH2)2 CH3 CF2Cl B24
A780 H CH3OCH2 CH3 CF2Cl B24
A781 H CH3O(CH2)2 CH3 CF2Cl B24
A782 H Ph CH3 CF2Cl B24
A783 H PhO CH3 CF2Cl B24
A784 H PhS CH3 CF2Cl B24
A785 H PhSO CH3 CF2Cl B24
A786 H PhSO2 CH3 CF2Cl B24
A787 H CH3S CH3 CF2Cl B24
A788 H CH3SO CH3 CF2Cl B24
A789 H CF3 CH3 CF2Cl B24
A790 H F2CH CH3 CF2Cl B24
A791 H HCC CH3 CF2Cl B24
A792 H CH3CC CH3 CF2Cl B24
A793 H CH2＝CH CH3 CF2Cl B24
A794 H CH2＝CHCH2 CH3 CF2Cl B24
A795 H CH3SO2N(CH3) CH3 CF2Cl B24
A796 H (CH3)2N CH3 CF2Cl B24
A797 H (CH3)2NSO2 CH3 CF2Cl B24
A798 H CH3SCH2 CH3 CF2Cl B24
A799 H CH3SOCH2 CH3 CF2Cl B24
A800 H CH3SO2CH2 CH3 CF2Cl B24
A801 H CH3 CH3 CHF2 B24
A802 H CH3CH2 CH3 CHF2 B24
A803 H 环丙基 CH3 CHF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A804 H (CH3)3C CH3 CHF2 B24
A805 H (CH3)2CH CH3 CHF2 B24
A806 H CH3(CH2)2 CH3 CHF2 B24
A807 H CH3OCH2 CH3 CHF2 B24
A808 H CH3O(CH2)2 CH3 CHF2 B24
A809 H Ph CH3 CHF2 B24
A810 H PhO CH3 CHF2 B24
A811 H PhS CH3 CHF2 B24
A812 H PhSO CH3 CHF2 B24
A813 H PhSO2 CH3 CHF2 B24
A814 H CH3S CH3 CHF2 B24
A815 H CH3SO CH3 CHF2 B24
A816 H CF3 CH3 CHF2 B24
A817 H F2CH CH3 CHF2 B24
A818 H HCC CH3 CHF2 B24
A819 H CH3CC CH3 CHF2 B24
A820 H CH2＝CH CH3 CHF2 B24
A821 H CH2＝CHCH2 CH3 CHF2 B24
A822 H CH3SO2N(CH3) CH3 CHF2 B24
A823 H (CH3)2N CH3 CHF2 B24
A824 H (CH3)2NSO2 CH3 CHF2 B24
A825 H CH3SCH2 CH3 CHF2 B24
A826 H CH3SOCH2 CH3 CHF2 B24
A827 H CH3SO2CH2 CH3 CHF2 B24
A828 H CH3 CH3 CCl3 B24
A829 H CH3CH2 CH3 CCl3 B24
A830 H 环丙基 CH3 CCl3 B24
A831 H (CH3)3C CH3 CCl3 B24
A832 H (CH3)2CH CH3 CCl3 B24
A833 H CH3(CH2)2 CH3 CCl3 B24
A834 H CH3OCH2 CH3 CCl3 B24
A835 H CH3O(CH2)2 CH3 CCl3 B24
化合物 R92 R93 R94 R95 Q3
序号
A836 H Ph CH3 CCl3 B24
A837 H PhO CH3 CCl3 B24
A838 H PhS CH3 CCl3 B24
A839 H PhSO CH3 CCl3 B24
A840 H PhSO2 CH3 CCl3 B24
A841 H CH3S CH3 CCl3 B24
A842 H CH3SO CH3 CCl3 B24
A843 H CF3 CH3 CCl3 B24
A844 H F2CH CH3 CCl3 B24
A845 H HCC CH3 CCl3 B24
A846 H CH3CC CH3 CCl3 B24
A847 H CH2＝CH CH3 CCl3 B24
A848 H CH2＝CHCH2 CH3 CCl3 B24
A849 H CH3SO2N(CH3) CH3 CCl3 B24
A850 H (CH3)2N CH3 CCl3 B24
A851 H (CH3)2NSO2 CH3 CCl3 B24
A852 H CH3SCH2 CH3 CCl3 B24
A853 H CH3SOCH2 CH3 CCl3 B24
A854 H CH3SO2CH2 CH3 CCl3 B24
A855 H CH3 Ph CF3 B24
A856 H CH3CH2 Ph CF3 B24
A857 H (CH3)2CH Ph CF3 B24
A858 H (CH3)2CH Ph CF3 B24
A859 H 环丙基 Ph CF3 B24
A860 H CH3(CH2)2 Ph CF3 B24
A861 H CH3OCH2 Ph CF3 B24
A862 H CH3O(CH2)2 Ph CF3 B24
A863 H Ph Ph CF3 B24
A864 H PhO Ph CF3 B24
A865 H PhS Ph CF3 B24
A866 H PhSO Ph CF3 B24
A867 H PhSO2 Ph CF3 B24
化合物 R92 R93 R94 R95 Q3
序号
A868 H CH3S Ph CF3 B24
A869 H CH3SO Ph CF3 B24
A870 H CF3 Ph CF3 B24
A871 H F2CH Ph CF3 B24
A872 H HCC Ph CF3 B24
A873 H CH3CC Ph CF3 B24
A874 H CH2＝CH Ph CF3 B24
A875 H CH2＝CHCH2 Ph CF3 B24
A876 H CH3SO2N(CH3) Ph CF3 B24
A877 H (CH3)2N Ph CF3 B24
A878 H (CH3)2NSO2 Ph CF3 B24
A879 H CH3SCH2 Ph CF3 B24
A880 H CH3SOCH2 Ph CF3 B24
A881 H CH3SO2CH2 Ph CF3 B24
A882 H CH3 Ph CF3CF2 B24
A883 H CH3CH2 Ph CF3CF2 B24
A884 H 环丙基 Ph CF3CF2 B24
A885 H (CH3)3C Ph CF3CF2 B24
A886 H (CH3)2CH Ph CF3CF2 B24
A887 H CH3(CH2)2 Ph CF3CF2 B24
A888 H CH3OCH2 Ph CF3CF2 B24
A889 H CH3O(CH2)2 Ph CF3CF2 B24
A890 H Ph Ph CF3CF2 B24
A891 H PhO Ph CF3CF2 B24
A892 H PhS Ph CF3CF2 B24
A893 H PhSO Ph CF3CF2 B24
A894 H PhSO2 Ph CF3CF2 B24
A895 H CH3S Ph CF3CF2 B24
A896 H CH3SO Ph CF3CF2 B24
A897 H CF3 Ph CF3CF2 B24
A898 H F2CH Ph CF3CF2 B24
A899 H HCC Ph CF3CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A900 H CH3CC Ph CF3CF2 B24
A901 H CH2＝CH Ph CF3CF2 B24
A902 H CH2＝CHCH2 Ph CF3CF2 B24
A903 H CH3SO2N(CH3) Ph CF3CF2 B24
A904 H (CH3)2N Ph CF3CF2 B24
A905 H (CH3)2NSO2 Ph CF3CF2 B24
A906 H CH3SCH2 Ph CF3CF2 B24
A907 H CH3SOCH2 Ph CF3CF2 B24
A908 H CH3SO2CH2 Ph CF3CF2 B24
A909 H CH3 Ph CF3CF2CF2 B24
A910 H CH3CH2 Ph CF3CF2CF2 B24
A911 H 环丙基 Ph CF3CF2CF2 B24
A912 H (CH3)3C Ph CF3CF2CF2 B24
A913 H (CH3)2CH Ph CF3CF2CF2 B24
A914 H CH3(CH2)2 Ph CF3CF2CF2 B24
A915 H CH3OCH2 Ph CF3CF2CF2 B24
A916 H CH3O(CH2)2 Ph CF3CF2CF2 B24
A917 H Ph Ph CF3CF2CF2 B24
A918 H PhO Ph CF3CF2CF2 B24
A919 H PhS Ph CF3CF2CF2 B24
A920 H PhSO Ph CF3CF2CF2 B24
A921 H PhSO2 Ph CF3CF2CF2 B24
A922 H CH3S Ph CF3CF2CF2 B24
A923 H CH3SO Ph CF3CF2CF2 B24
A924 H CF3 Ph CF3CF2CF2 B24
A925 H F2CH Ph CF3CF2CF2 B24
A926 H HCC Ph CF3CF2CF2 B24
A927 H CH3CC Ph CF3CF2CF2 B24
A928 H CH2＝CH Ph CF3CF2CF2 B24
A929 H CH2＝CHCH2 Ph CF3CF2CF2 B24
A930 H CH3SO2N(CH3) Ph CF3CF2CF2 B24
A931 H (CH3)2N Ph CF3CF2CF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A932 H (CH3)2NSO2 Ph CF3CF2CF2 B24
A933 H CH3SCH2 Ph CF3CF2CF2 B24
A934 H CH3SOCH2 Ph CF3CF2CF2 B24
A935 H CH3SO2CH2 Ph CF3CF2CF2 B24
A936 H CH3 Ph CF2Cl B24
A937 H CH3CH2 Ph CF2Cl B24
A938 H 环丙基 Ph CF2Cl B24
A939 H (CH3)3C Ph CF2Cl B24
A940 H (CH3)2CH Ph CF2Cl B24
A941 H CH3(CH2)2 Ph CF2Cl B24
A942 H CH3OCH2 Ph CF2Cl B24
A943 H CH3O(CH2)2 Ph CF2Cl B24
A944 H Ph Ph CF2Cl B24
A945 H PhO Ph CF2Cl B24
A946 H PhS Ph CF2Cl B24
A947 H PhSO Ph CF2Cl B24
A948 H PhSO2 Ph CF2Cl B24
A949 H CH3S Ph CF2Cl B24
A950 H CH3SO Ph CF2Cl B24
A951 H CF3 Ph CF2Cl B24
A952 H F2CH Ph CF2Cl B24
A953 H HCC Ph CF2Cl B24
A954 H CH3CC Ph CF2Cl B24
A955 H CH2＝CH Ph CF2Cl B24
A956 H CH2＝CHCH2 Ph CF2Cl B24
A957 H CH3SO2N(CH3) Ph CF2Cl B24
A958 H (CH3)2N Ph CF2Cl B24
A959 H (CH3)2NSO2 Ph CF2Cl B24
A960 H CH3SCH2 Ph CF2Cl B24
A961 H CH3SOCH2 Ph CF2Cl B24
A962 H CH3SO2CH2 Ph CF2Cl B24
A963 H CH3 Ph CHF2 B24
化合物 R92 R93 R94 R95 Q3
序号
A964 H CH3CH2 Ph CHF2 B24
A965 H (CH3)3C Ph CHF2 B24
A966 H (CH3)2CH Ph CHF2 B24
A967 H 环丙基 Ph CHF2 B24
A968 H CH3(CH2)2 Ph CHF2 B24
A969 H CH3OCH2 Ph CHF2 B24
A970 H CH3O(CH2)2 Ph CHF2 B24
A971 H Ph Ph CHF2 B24
A972 H PhO Ph CHF2 B24
A973 H PhS Ph CHF2 B24
A974 H PhSO Ph CHF2 B24
A975 H 
Ph CHF2 B24
A976 H CH3S Ph CHF2 B24
A977 H CH3SO Ph CHF2 B24
A978 H CF3 Ph CHF2 B24
A979 H F2CH Ph CHF2 B24
A980 H HCC Ph CHF2 B24
A981 H CH3CC Ph CHF2 B24
A982 H CH2＝CH Ph CHF2 B24
A983 H CH2＝CHCH2 Ph CHF2 B24
A984 H CH3SO2N(CH3) Ph CHF2 B24
A985 H (CH3)2N Ph CHF2 B24
A986 H (CH3)2NSO2 Ph CHF2 B24
A987 H CH3SCH2 Ph CHF2 B24
A988 H CH3SOCH2 Ph CHF2 B24
A989 H CH3SO2CH2 Ph CHF2 B24
A990 H CH3 Ph CCl3 B24
A991 H CH3CH2 Ph CCl3 B24
A992 H (CH3)3C Ph CCl3 B24
A993 H (CH3)2CH Ph CCl3 B24
A994 H 环丙基 Ph CCl3 B24
A995 H CH3(CH2)2 Ph CCl3 B24
化合物 R92 R93 R94 R95 Q3
序号
A996 H CH3OCH2 Ph CCl3 B24
A997 H CH3O(CH2)2 Ph CCl3 B24
A998 H Ph Ph CCl3 B24
A999 H PhO Ph CCl3 B24
A1000 H PhS Ph CCl3 B24
A1001 H PhSO Ph CCl3 B24
A1002 H PhSO2 Ph CCl3 B24
A1003 H CH3S Ph CCl3 B24
A1004 H CH3SO Ph CCl3 B24
A1005 H CF3 Ph CCl3 B24
A1006 H F2CH Ph CCl3 B24
A1007 H HCC Ph CCl3 B24
A1008 H CH3CC Ph CCl3 B24
A1009 H CH2＝CH Ph CCl3 B24
A1010 H CH2＝CHCH2 Ph CCl3 B24
A1011 H CH3SO2N(CH3) Ph CCl3 B24
A1012 H (CH3)2N Ph CCl3 B24
A1013 H (CH3)2NSO2 Ph CCl3 B24
A1014 H CH3SCH2 Ph CCl3 B24
A1015 H CH3SOCH2 Ph CCl3 B24
A1016 H CH3SO2CH2 Ph CCl3 B24
A1017 F H H CF3 B24
A1018 Cl H H CF3 B24
A1019 Br H H CF3 B24
A1020 CN H H CF3 B24
A1021 CH3SO2O H H CF3 B24
A1022 CH3O H H CF3 B24
A1023 CH2CH3O H H CF3 B24
A1024 CH2CH＝CH2O H H CF3 B24
A1025 HCCCH2O H H CF3 B24
A1026 S-苄基 H H CF3 B24
A1027 SO2-苄基 H H CF3 B24
化合物 R92 R93 R94 R95 Q3
序号
A1028 ClCH2 H H CF3 B24
A1029 BrCH2 H H CF3 B24
A1030 FCH2 H H CF3 B24
A1031 CHF2CH2 H H CF3 B24
A1032 CF3CH2 H H CF3 B24
A1033 三唑基甲基 H H CF3 B24
A1034 CHCl2CH2 H H CF3 B24
A1035 ClCH＝CH H H CF3 B24
A1036 Cl2C＝CH H H CF3 B24
A1037 CF3CH＝CH H H CF3 B24
A1038 ClCC H H CF3 B24
A1039 Ph H H CF3 B24
A1040 CH3 CH3 H CF3 B24
A1041 CH3 OH H CF3 B24
A1042 CH3 F H CF3 B24
A1043 CH3 Cl H CF3 B24
A1044 F CH3 H CF3 B24
A1045 Cl CH3 H CF3 B24
A1046 H F H CF3 B24
A1047 H Cl H CF3 B24
A1048 H Br H CF3 B24
A1049 H OH H CF3 B24
A1050 H OCH3 H CF3 B24
A1051 H OCHF2 H CF3 B24
A1052 H OSO2CH3 H CF3 B24
A1053 H OSO2CF3 H CF3 B24
A1054 H ClCH2 H CF3 B24
A1055 H BrCH2 H CF3 B24
A1056 H FCH2 H CF3 B24
A1057 H CHF2CH2 H CF3 B24
A1058 H CF3CH2 H CF3 B24
A1059 H 三唑基甲基 H CF3 B24
化合物 R92 R93 R94 R95 Q3
序号
A1060 H CHCl2CH2 H CF3 B24
A1061 H ClCH＝CH H CF3 B24
A1062 H Cl2C＝CH H CF3 B24
A1063 H CF3CH＝CH H CF3 B24
A1064 H ClCC H CF3 B24
A1065 H CH3C(O) H CF3 B24
A1066 H 苯基 H CF3 B24
A1067 H SO2CH3 H CF3 B24
A1068 H SO2CF3 H CF3 B24
A1069 H CN H CF3 B24
A1070 H NO2 H CF3 B24
A1071 CH3 H F CF3 B24
A1072 CH3 H Cl CF3 B24
A1073 CH3 H Br CF3 B24
A1074 CH3 H CN CF3 B24
A1075 CH3 H CH3O CF3 B24
A1076 CH3 H CH3S CF3 B24
A1077 CH3 H CH3SO CF3 B24
A1078 CH3 H CH3SO2 CF3 B24
表9a：式Ig化合物：
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 B12
B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24
B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36
B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60
B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72
B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84
B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96
B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108
B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120
B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132
B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144
B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156
B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168
B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180
B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192
B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204
B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216
B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228
B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240
B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252
B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264
B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276
B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288
B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300
B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312
B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324
B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336
B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348
B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360
B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372
B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384
B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396
B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408
B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420
B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432
B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456
B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468
B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480
B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492
B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504
B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516
B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528
B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540
B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552
B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564
B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576
B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588
B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600
B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612
B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624
B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636
B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648
B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660
B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672
B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784
B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796
B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808
B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820
B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832
B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844
B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856
B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868
B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880
B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892
B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904
B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916
B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928
B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952
B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964
B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976
B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988
B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000
B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012
B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024
B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036
B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048
B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060
B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072
B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083
表10：式Ih化合物：
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 B12
B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24
B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36
B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48
B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60
B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72
B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84
B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96
B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108
B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120
B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132
B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156
B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168
B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180
B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192
B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204
B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216
B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228
B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240
B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252
B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264
B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276
B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288
B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300
B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312
B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324
B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336
B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348
B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360
B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372
B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384
B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396
B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408
B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420
B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432
B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444
B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456
B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468
B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480
B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492
B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504
B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516
B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528
B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552
B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564
B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576
B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588
B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600
B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612
B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624
B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636
B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648
B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660
B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672
B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784
B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796
B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808
B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820
B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832
B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844
B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856
B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868
B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880
B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892
B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904
B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916
B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928
B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940
B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952
B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964
B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976
B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988
B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000
B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012
B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024
B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048
B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060
B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072
B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083
表11：式Ik化合物：
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 B12
B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24
B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36
B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48
B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60
B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72
B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84
B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96
B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108
B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120
B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132
B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144
B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156
B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168
B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180
B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192
B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204
B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216
B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228
B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252
B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264
B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276
B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288
B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300
B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312
B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324
B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336
B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348
B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360
B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372
B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384
B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396
B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408
B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420
B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432
B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444
B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456
B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468
B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480
B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492
B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504
B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516
B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528
B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540
B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552
B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564
B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576
B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588
B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600
B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612
B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624
B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648
B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660
B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672
B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784
B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796
B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808
B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820
B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832
B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844
B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856
B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868
B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880
B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892
B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904
B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916
B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928
B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940
B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952
B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964
B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976
B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988
B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000
B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012
B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024
B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036
B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048
B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060
B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072
B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083
表12：式Im化合物：
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 B12
B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24
B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36
B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48
B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60
B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72
B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84
B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96
B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108
B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120
B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132
B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144
B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156
B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168
B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180
B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192
B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204
B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216
B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228
B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240
B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252
B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264
B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276
B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288
B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300
B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312
B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336
B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348
B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360
B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372
B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384
B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396
B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408
B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420
B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432
B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444
B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456
B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468
B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480
B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492
B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504
B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516
B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528
B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540
B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552
B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564
B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576
B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588
B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600
B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612
B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624
B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636
B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648
B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660
B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672
B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784
B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796
B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808
B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832
B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844
B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856
B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868
B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880
B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892
B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904
B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916
B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928
B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940
B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952
B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964
B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976
B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988
B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000
B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012
B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024
B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036
B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048
B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060
B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072
B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083
表13：式In化合物：
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 B12
B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36
B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48
B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60
B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72
B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84
B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96
B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108
B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120
B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132
B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144
B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156
B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168
B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180
B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192
B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204
B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216
B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228
B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240
B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252
B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264
B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276
B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288
B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300
B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312
B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324
B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336
B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348
B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360
B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372
B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384
B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396
B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408
B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432
B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444
B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456
B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468
B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480
B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492
B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504
B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516
B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528
B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540
B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552
B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564
B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576
B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588
B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600
B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612
B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624
B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636
B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648
B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660
B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672
B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784
B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796
B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808
B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820
B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832
B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844
B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856
B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868
B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880
B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892
B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904
B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928
B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940
B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952
B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964
B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976
B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988
B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000
B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012
B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024
B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036
B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048
B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060
B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072
B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083
表14：式Io化合物：
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 B12
B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24
B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36
B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48
B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60
B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72
B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84
B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96
B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108
B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132
B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144
B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156
B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168
B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180
B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192
B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204
B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216
B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228
B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240
B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252
B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264
B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276
B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288
B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300
B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312
B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324
B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336
B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348
B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360
B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372
B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384
B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396
B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408
B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420
B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432
B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444
B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456
B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468
B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480
B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492
B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504
B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528
B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540
B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552
B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564
B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576
B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588
B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600
B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612
B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624
B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636
B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648
B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660
B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672
B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784
B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796
B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808
B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820
B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832
B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844
B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856
B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868
B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880
B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892
B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904
B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916
B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928
B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940
B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952
B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964
B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976
B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988
B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000
B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024
B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036
B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048
B1048 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060
B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072
B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083
表15：式Ip化合物：
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 B12
B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24
B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36
B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48
B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60
B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72
B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84
B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96
B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108
B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120
B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132
B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144
B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156
B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168
B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180
B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192
B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216
B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228
B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240
B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252
B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264
B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276
B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288
B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300
B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312
B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324
B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336
B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348
B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360
B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372
B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384
B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396
B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408
B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420
B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432
B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444
B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456
B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468
B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480
B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492
B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504
B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516
B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528
B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540
B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552
B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564
B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576
B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588
B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612
B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624
B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636
B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648
B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660
B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672
B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784
B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796
B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808
B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820
B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832
B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844
B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856
B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868
B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880
B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892
B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904
B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916
B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928
B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940
B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952
B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964
B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976
B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988
B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000
B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012
B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024
B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036
B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048
B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060
B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072
B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083
表16：式Iq化合物：
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 B12
B13 B14 B15 B16 B17 B18 B19 B20 B21 B22 B23 B24
B25 B26 B27 B28 B29 B30 B31 B32 B33 B34 B35 B36
B37 B38 B39 B40 B41 B42 B43 B44 B45 B46 B47 B48
B49 B50 B51 B52 B53 B54 B55 B56 B57 B58 B59 B60
B61 B62 B63 B64 B65 B66 B67 B68 B69 B70 B71 B72
B73 B74 B75 B76 B77 B78 B79 B80 B81 B82 B83 B84
B85 B86 B87 B88 B89 B90 B91 B92 B93 B94 B95 B96
B97 B98 B99 B100 B101 B102 B103 B104 B105 B106 B107 B108
B109 B110 B111 B112 B113 B114 B115 B116 B117 B118 B119 B120
B121 B122 B123 B124 B125 B126 B127 B128 B129 B130 B131 B132
B133 B134 B135 B136 B137 B138 B139 B140 B141 B142 B143 B144
B145 B146 B147 B148 B149 B150 B151 B152 B153 B154 B155 B156
B157 B158 B159 B160 B161 B162 B163 B164 B165 B166 B167 B168
B169 B170 B171 B172 B173 B174 B175 B176 B177 B178 B179 B180
B181 B182 B183 B184 B185 B186 B187 B188 B189 B190 B191 B192
B193 B194 B195 B196 B197 B198 B199 B200 B201 B202 B203 B204
B205 B206 B207 B208 B209 B210 B211 B212 B213 B214 B215 B216
B217 B218 B219 B220 B221 B222 B223 B224 B225 B226 B227 B228
B229 B230 B231 B232 B233 B234 B235 B236 B237 B238 B239 B240
B241 B242 B243 B244 B245 B246 B247 B248 B249 B250 B251 B252
B253 B254 B255 B256 B257 B258 B259 B260 B261 B262 B263 B264
B265 B266 B267 B268 B269 B270 B271 B272 B273 B274 B275 B276
B277 B278 B279 B280 B281 B282 B283 B284 B285 B286 B287 B288
B289 B290 B291 B292 B293 B294 B295 B296 B297 B298 B299 B300
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B301 B302 B303 B304 B305 B306 B307 B308 B309 B310 B311 B312
B313 B314 B315 B316 B317 B318 B319 B320 B321 B322 B323 B324
B325 B326 B327 B328 B329 B330 B331 B332 B333 B334 B335 B336
B337 B338 B339 B340 B341 B342 B343 B344 B345 B346 B347 B348
B349 B350 B351 B352 B353 B354 B355 B356 B357 B358 B359 B360
B361 B362 B363 B364 B365 B366 B367 B368 B369 B370 B371 B372
B373 B374 B375 B376 B377 B378 B379 B380 B381 B382 B383 B384
B385 B386 B387 B388 B389 B390 B391 B392 B393 B394 B395 B396
B397 B398 B399 B400 B401 B402 B403 B404 B405 B406 B407 B408
B409 B410 B411 B412 B413 B414 B415 B416 B417 B418 B419 B420
B421 B422 B423 B424 B425 B426 B427 B428 B429 B430 B431 B432
B433 B434 B435 B436 B437 B438 B439 B440 B441 B442 B443 B444
B445 B446 B447 B448 B449 B450 B451 B452 B453 B454 B455 B456
B457 B458 B459 B460 B461 B462 B463 B464 B465 B466 B467 B468
B469 B470 B471 B472 B473 B474 B475 B476 B477 B478 B479 B480
B481 B482 B483 B484 B485 B486 B487 B488 B489 B490 B491 B492
B493 B494 B495 B496 B497 B498 B499 B500 B501 B502 B503 B504
B505 B506 B507 B508 B509 B510 B511 B512 B513 B514 B515 B516
B517 B518 B519 B520 B521 B522 B523 B524 B525 B526 B527 B528
B529 B530 B531 B532 B533 B534 B535 B536 B537 B538 B539 B540
B541 B542 B543 B544 B545 B546 B547 B548 B549 B550 B551 B552
B553 B554 B555 B556 B557 B558 B559 B560 B561 B562 B563 B564
B565 B566 B567 B568 B569 B570 B571 B572 B573 B574 B575 B576
B577 B578 B579 B580 B581 B582 B583 B584 B585 B586 B587 B588
B589 B590 B591 B592 B593 B594 B595 B596 B597 B598 B599 B600
B601 B602 B603 B604 B605 B606 B607 B608 B609 B610 B611 B612
B613 B614 B615 B616 B617 B618 B619 B620 B621 B622 B623 B624
B625 B626 B627 B628 B629 B630 B631 B632 B633 B634 B635 B636
B637 B638 B639 B640 B641 B642 B643 B644 B645 B646 B647 B648
B649 B650 B651 B652 B653 B654 B655 B656 B657 B658 B659 B660
B661 B662 B663 B664 B665 B666 B667 B668 B669 B670 B671 B672
B773 B774 B775 B776 B777 B778 B779 B780 B781 B782 B783 B784
B785 B786 B787 B788 B789 B790 B791 B792 B793 B794 B795 B796
Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3 Q3
B797 B798 B799 B800 B801 B802 B803 B804 B805 B806 B807 B808
B809 B810 B811 B812 B813 B814 B815 B816 B817 B818 B819 B820
B821 B822 B823 B824 B825 B826 B827 B828 B829 B830 B831 B832
B833 B834 B835 B836 B837 B838 B839 B840 B841 B842 B843 B844
B845 B846 B847 B848 B849 B850 B851 B852 B853 B854 B855 B856
B857 B858 B859 B860 B861 B862 B863 B864 B865 B866 B867 B868
B869 B870 B871 B872 B873 B874 B875 B876 B877 B878 B879 B880
B881 B882 B883 B884 B885 B886 B887 B888 B889 B890 B891 B892
B893 B894 B895 B896 B897 B898 B899 B900 B901 B902 B903 B904
B905 B906 B907 B908 B909 B910 B911 B912 B913 B914 B915 B916
B917 B918 B919 B920 B921 B922 B923 B924 B925 B926 B927 B928
B929 B930 B931 B932 B933 B934 B935 B936 B937 B938 B939 B940
B941 B942 B943 B944 B945 B946 B947 B948 B949 B950 B951 B952
B953 B954 B955 B956 B957 B958 B959 B960 B961 B962 B963 B964
B965 B966 B967 B968 B969 B970 B971 B972 B973 B974 B975 B976
B977 B978 B979 B980 B981 B982 B983 B984 B985 B986 B987 B988
B989 B990 B991 B992 B993 B994 B995 B996 B997 B998 B999 B1000
B1001 B1002 B1003 B1004 B1005 B1006 B1007 B1008 B1009 B1010 B1011 B1012
B1013 B1014 B1015 B1016 B1017 B1018 B1019 B1020 B1021 B1022 B1023 B1024
B1025 B1026 B1027 B1028 B1029 B1030 B1031 B1032 B1033 B1034 B1035 B1036
B1037 B1038 B1039 B1040 B1041 B1042 B1043 B1044 B1045 B1046 B1047 B1048
B1049 B1050 B1051 B1052 B1053 B1054 B1055 B1056 B1057 B1058 B1059 B1060
B1061 B1062 B1063 B1064 B1065 B1066 B1067 B1068 B1069 B1070 B1071 B1072
B1073 B1074 B1075 B1076 B1077 B1078 B1079 B1080 B1081 B1082 B1083
表17：式Ir化合物：
Q6 Q6 Q6 Q6 Q6 Q6 Q6 Q6 Q6 Q6 Q6 Q6
Q6 Q6 Q6 Q6 Q6 Q6 Q6 Q6 Q6 Q6 Q6 Q6
C1 C2 C3 C4 C5 C6 C7 C8 C9 C10 C11 C12
C13 C14 C15 C16 C17 C18 C19 C20 C21 C22 C23 C24
C25 C26 C27 C28 C29 C30 C31 C32 C33 C34 C35 C36
C37 C38 C39 C40 C41 C42 C43 C44 C45 C46 C47 C48
C49 C50 C51 C52 C53 C54 C55 C56 C57 C58 C59 C60
C61 C62 C63 C64 C65 C66 C67 C68 C69 C70 C71 C72
C73 C74 C75 C76 C77 C78 C79 C80 C81 C82 C83 C84
C85 C86 C87 C88 C89 C90 C91 C92 C93 C94 C95 C96
C97 C98 C99 C100 C101 C102 C103 C104 C105 C106 C107 C108
C109 C110 C111 C112 C113 C114 C115 C116 C117 C118 C119 C120
C121 C122 C123 C124 C125 C126 C127 C128 C129 C130 C131 C132
C133 C134 C135 C136 C137 C138 C139 C140 C141 C142 C143 C144
C145 C146 C147 C148 C149 C150 C151
表18：式Is化合物：
Q7 Q7 Q7 Q7 Q7 Q7 Q7 Q7 Q7 Q7 Q7 Q7
D1 D2 D3 D4 D5 D6 D7 D8 D9 D10 D11 D12
D13 D14 D15 D16 D17 D18 D19 D20 D21 D22 D23 D24
D25 D26 D27 D28 D29 D30 D31 D32 D33 D34 D35 D36
D37 D38 D39 D40 D41 D42 D43 D44 D45 D46 D47 D48
D49 D50 D51 D52 D53 D54 D55 D56 D57 D58 D59 D60
D61 D62 D63 D64 D65 D66 D67 D68 D69 D70 D71 D72
D73 D74 D75 D76 D77 D78 D79 D80 D81 D82 D83 D84
D85 D86 D87 D88 D89 D90 D91 D92 D93 D94 D95 D96
D97 D98 D99 D100 D101 D102 D103 D104 D105 D106 D107 D108
D109 D110 D111 D112 D113 D114 D115 D116 D117 D118 D119 D120
Q7 Q7 Q7 Q7 Q7 Q7 Q7 Q7 Q7 Q7 Q7 Q7
D121 D122 D123 D124 D125 D126 D127 D128 D129 D130 D131 D132
D133 D134 D135 D136 D137 D138 D139 D140
表19：式Iv化合物：
化合物序号 R75
E1 CH2OCH3
E2 CH2OC2H5
E3 CH2O-正丙基
E4 CH2O-异丙基
E5 CH2O-正丁基
E6 CH2O-异丁基
E7 CH2O-叔丁基
E8 (CH2)2OCH3
E9 (CH2)2O-乙基
E10 (CH2)2O-正丙基
E11 (CH2)2O-异丙基
E12 (CH2)2O-正丁基
E13 (CH2)2O-异丁基
E14 (CH2)2O-叔丁基
E15 (CH2)2O(CH2)2OCH3
E16 (CH2)2O(CH2)2OCH3
E17 C2H5
表20：表5-19的物理数据(数据＝m.p.，单位为℃)：
化合物 物理数据 化合物 物理数据 化合物 物理数据
A2 150-151 C46 159-161 A2-B1058 88-89
A3 148-149 C91 141-143 A2-B1066 粘稠物
A4 143-144 C146 99-101 A2-B1067 树脂油状物
A5 81-82 C149 148-150 A2-B1069 油状物
A6 148-150 A2-B1 90-92 A2-B1069 粘稠油状物
A7 105-106 A2-B68 120-121 A8-B1 97-98
A8 123-124 A2-B2 树脂状物 A7-B1 油状物
A9 73-74 A2-B90 树脂状物 A3-B1 42-44
A10 165-167 A2-B93 95-96 A94-B1 57-58
A15 164-166 A2-B46 61-62顺式-rac A66-B24 80-82
A17 99-100 A2-B46 83-84反式-rac A64-B1 49-51
A26 143-144 A2-B91 树脂状物 A154-B1 94-95
A27 107-108 A2-B1081 油状物 A6-B1 123-124
A29 173-174 A2-B1082 树脂状物 A6-B24 油状物
A30 178-181 A2-B1083 树脂状物 A34-B1 53-54
A31 209-210 A2-B29 87-88 A2-B25 油状物
A32 145-146 A2-B73 树脂状物 A2-B925 油状物
A34 170-171 A2-B95 106-107 E8 55-56
A64 134-135 A2-B31 151-153 E17 99-101
A94 134-135 A2-B75 无定形物
A154 108-110 A2-B24 油状物
B1057 166-167 A2-B5 树脂状物
B1058 结晶 A2-C91 树脂状物
B1061 结晶 A2-C146 油状物
B1063 结晶 A2-B112 树脂状物
B1065 油状物 A2-D140 油状物
B1066 150-152 A2-B1057 无定形物
B1067 122-123 A2-B1063 油状物
B1069 117-118 A2-B1061 油状物
B1070 结晶 A2-B133 油状物
式2.1和2.3-2.13.c化合物的名称是甲氧咪草烟、咪唑乙烟酸、咪唑喹啉酸、咪唑烟酸、二甲吩草胺、莠去津、特丁津、西玛津、特丁净、氰乙酰肼、莠灭净、甲氧去草净、调环酸钙、稀禾定、烯草酮、吡喃草酮(tepraloxydim)、唑嘧磺草胺、磺草唑胺、哒草特、溴苯腈、碘苯腈、磺草酮、唑酮草酯(carfentrazone)、甲磺草胺、异噁唑草酮、草铵膦、氟嘧磺隆、氟磺隆、砜嘧磺隆、氯吡嘧磺隆、烟嘧磺隆、乙氧嘧磺隆、啶嘧磺隆和噻吩磺隆，并且以下列条目号描述在《农药手册》(PesticideManual)，第11版，英国作物保护委员会(British Crop ProtectionCouncil)，1997中：412、415、414、413、240、34、692、651、693、168、20、691、595、648、146、49、339、495、626、88、425、664、112、665、436、382、589、613、644、389、519、287、325和704。其中Y1、Y3和Y4是次甲基，Y2是C-I，R74是COOMe，Y5是氮，Y6是甲基，且Y7是甲氧基的式2.13化合物以名称碘甲磺隆(尤其是钠盐)描述在AGROWNo.296，16th 1月1998，p.22中。其中Y1、Y2、Y3和Y4是次甲基，R74是三氟甲基，Y5是氮，Y6是三氟甲基，且Y7是甲氧基的式2.13化合物的名称是甲酰氨磺隆，并描述在DE-A-40 38 430中。其中Y1是NH-CHO，Y2、Y3和Y4是次甲基，R74是CONMe2，Y5是次甲基，且Y6和Y7是甲氧基的式2.13化合物描述在例如WO 95/29899中。
式2.12化合物的S对映体以CAS-Reg.No.[35597-44-5]登记。通式2.2化合物，aRS，1’S(-)N-(1’-甲基-2’-甲氧基-乙基)-N-氯乙酰基-2-乙基-6-甲基苯胺，和通式2.3化合物，(1S，aRS)-2-氯-N-(2，4-二甲基-3-噻吩基)-N-(2-甲氧基-1-甲基乙基)-乙酰胺描述在例如WO97/34485中。其中R69是NO2的式2.9化合物的名称是甲基磺草酮，并且描述在例如US-A-5 006 158中。其中R62是乙氧基，R63是氟，Y是次甲基，R64是甲氧基羰基，R65是氢，且R66是氯的式2.6化合物的名称是氯酯磺草胺(cloransulam)，并描述在例如AGROW No.261，2nd 8月1996，p.21中。其中R62是甲氧基，R63是氢，Y是C-F，R64是氟，R65是氢，且R66是氟的式2.6化合物的名称是双氟磺草胺，并描述在US-A-5 163 995中。
此外，本发明组合物的下列化合物描述在《农药手册》(PesticideManual)，第11版，英国作物保护委员会(British Crop ProtectionCouncil)，1997中：
式化合物(名称) 《农药手册》第11版，条目号
2.14(嗪草酮) 497
2.15(苯草醚) 8
2.16(草甘膦) 383
2.1 7(灭草松) 65
2.18(二甲戊灵) 557
2.19(麦草畏) 210
2.20(丁草敌) 100
2.22(异恶草松) 150
2.23(2，4-D) 192
2.24(氟烯草酸) 340
2.25(氟噻甲草酯) 359
2.26(呋草酮) 356
2.27(丙炔氟草胺) 341
2.28(百草枯) 550
2.29(唑啶草酮) 37
2.30(fluthiamid) 51
2.33(sulfosate) 383
2.34(磺草灵) 33
2.35(氟草敏) 526
2.36(特草定) 689
2.37(噻唑烟酸) 702
2.38(氟硫草定) 259
2.39(环嗪酮) 400
2.40(敌草隆) 260
2.41(MCPA) 455
2.42(甲氯丙酸) 459
2.43(丁噻隆) 683
其中R67是氢的式2.7化合物及其制备描述在US-A-3 790 571中；其中R62是乙氧基，Z是氮，R63是氟，R64是氯，R65是氢，且R66是氯的式2.6化合物描述在US-A-5 498 773中。式2.21化合物及其制备描述在US-A-5 183 492中；式2.22化合物以名称双环磺草酮描述在AGROW No.296，16th 1月1998，p.22中。式2.31化合物以名称四唑酰草胺描述在1997年英国作物保护会议-杂草，会议论文集(The 1997 British CropProtection Conference-Weeds，Conference Proceedings)Vol.1，2-8，p.67-72中；式2.32化合物以名称JV 485(isoxapropazol)描述在1997年英国作物保护会议-杂草，会议论文集Vol.1，3A-2，p.93-98中。式2.44化合物的名称是pethoxamid，并描述在EP-A-0 206 251中。式2.45化合物的名称是丙苯磺隆，并描述在EP-A-0 507 171中；式2.46化合物的名称是异丙吡草酯，并描述在例如US-A-5 530 126中。式2.47化合物的名称是吲哚酮草酯，并描述在例如DE-A-4 037 840中。式2.48化合物的名称是双苯嘧草酮，并描述在例如WO 97/08953中。式2.49化合物的名称是氟吡草腙，并描述在例如EP-A-0 646 315中。式2.50化合物(氨唑草酮)及其制备公开在DD 298 393和US-A-5 194 085中。式2.51化合物(flufenpyr-ethyl)描述在美国化学会论文文摘(Abstractsof Papers American Chemical Society)，(2000)Vol.220，No.部分1，pp.AGRO 174中。
非常令人惊奇的是，式I活性组分与一种或多种选自式2.1-2.51的活性组分的组合对欲控制杂草的作用超过了一般所预计的加和作用，因此扩大了单独活性组分的作用范围，尤其是在下列两个方面：首先，减小了单独的式2.1-2.51化合物的施用量，同时保持了良好的作用水平，其次，对于单独的活性物质以低施用量不可用的情况(从农学角度来看)，本发明组合物亦可获得良好的杂草控制水平。该结果是杂草谱的显著拓宽，并且提高了在有用植物农作物方面的选择性，如果发生了活性组分的非故意剂量过多，这样的结果是必须的并且希望的。在保持良好控制有用植物农作物中的杂草的同时，本发明组合物还使得在继代农作物中有更大的灵活性。
本发明组合物可用于抗大量在农业上很重要的杂草，例如繁缕属、豆瓣菜属、剪股颖属、马唐属、燕麦属、狗尾草属、芥属、毒麦属、茄属、菜豆属、稗属、藨草属、雨久花属、慈菇属、雀麦属、看麦娘属、石茅高梁、筒轴茅属、莎草属、苘麻属植物、黄花稔属、苍耳属、苋属、藜属、番薯属、苘蒿属、猪殃殃属、堇菜属和婆婆纳属。本发明组合物适用于农业中的所有常用施用方法，例如芽前施用、苗后施用和种子包衣。本发明组合物尤其适用于控制有用植物农作物例如禾谷类植物、油菜、甜菜、甘蔗、种植园农作物、稻、玉米和大豆中的杂草，以及适用于非选择性杂草控制。“农作物”还指通过常规育种或基因工程方法使其对除草剂或除草剂类别耐受的农作物。本发明还提供了控制有用植物农作物中不希望的植物生长的方法。该方法包括将除草有效量的本发明组合物作用于农作物植物或其场所。
本发明组合物包含任意混合比例的式I活性组分和式2.1-2.51活性组分，但是其中一种组分的量通常超过另一种组分的量。式I活性组分与式2.1-2.51混合配伍的混合比例(重量比)一般为1∶2000-2000∶1、尤其是200∶1-1∶200。
施用量可在宽的限度内变化，并取决于土壤性质、施用方法(芽前或苗后；种子包衣；播沟施用；非耕种施用等)、农作物植物、欲控制的杂草、主要的气候条件、和由施用方法控制的其它因素、施用时间和目标农作物。本发明活性组分混合物一般可以以1-5000g活性组分混合物/公顷的比例施用。
式I化合物与式式2.1-2.51化合物的混合物可以以未改性的形式使用，也就是说，以合成所获得的形式使用。然而，优选以常规方式将它们与制剂技术常用的助剂例如溶剂、固体载体或表面活性剂一起加工配制，例如配制成乳油、可直接喷雾或稀释的溶液、稀的乳剂、可湿性粉剂、可溶性粉剂、粉尘剂、粒剂或微胶囊。根据使用目的和主要环境来选择作为组合物性质的施用方法例如喷雾、雾化、撒布、润湿、撒施或浇泼。
制剂，即包含式I和式2.1-2.51化合物(活性组分)、以及适当时一种或多种固体或液体制剂助剂的组合物、制剂或混合物是以自身已知的方式制得的，例如通过将活性组分与制剂助剂例如溶剂或固体载体充分混合和/或研磨而制得。此外，在制剂的制备中可使用表面活性化合物(表面活性剂)。
溶剂和固体载体的实例描述在例如WO 97/34485第6页中。
根据欲配制的式I化合物的性质，合适的表面活性化合物是具有良好乳化、分散和润湿性质的非离子、阳离子和/或阴离子表面活性剂以及表面活性剂混合物。
合适的阴离子、非离子和阳离子表面活性剂描述在例如WO 97/34485第7和8页中。
制剂技术常用的表面活性剂也适用于本发明除草组合物的制备，这些表面活性剂特别描述在《 McCutcheon洗涤剂和乳化剂年鉴》(″McCutcheon’s Detergents and Emulsifiers Annual″)MC PublishingCorp.，Ridgewood New Jersey，1981，Stache，H.，″Tensid-Taschenbuch″，Carl Hanser Verlag，Munich/Nienna， 1981以及M.和J.Ash，《表面活性剂大全》(″Encyclopedia of Surfactants″)，Vol 1-111，Chemical Publishing Co.，New York，1980-81中。
除草制剂通常含有0.1-99％重量、尤其是0.1-95％重量的包含式I化合物和式2.1-2.51化合物的活性组分混合物，1-99.9％重量的固体或液体制剂助剂，和0-25％重量、尤其是0.1-25％重量的表面活性剂。
然而，市售产品一般是配制成浓缩物，最终的使用者通常使用稀释的制剂。组合物还可以含有其它组分，例如稳定剂如植物油或环氧化植物油(环氧化椰子油、菜籽油或豆油)，消泡剂例如硅油，防腐剂，粘度调节剂，粘合剂，增粘剂，以及肥料和其它活性组分。优选的制剂具有尤其是下列组成：
(％＝重量百分比)
乳油：
活性组分混合物：1-90％、优选5-20％
表面活性剂： 1-30％、优选10-20％
液体载体： 5-94％、优选70-85％
粉剂：
活性组分混合物：0.1-10％、优选0.1-5％
固体载体： 99.9-90％、优选99.9-99％
胶悬剂：
活性组分混合物：5-75％、优选10-50％
水： 94-24％、优选88-30％
表面活性剂： 1-40％、优选2-30％
可湿性粉剂：
活性组分混合物：0.5-90％、优选1-80％
表面活性剂： 0.5-20％、优选1-15％
固体载体： 5-95％、优选15-90％
粒剂：
活性组分混合物：0.1-30％、优选0.1-15％
固体载体： 99.5-70％、优选97-85％
下列实施例进一步举例说明了本发明，但不是限制本发明。
F1.乳油 a) b) c) d)
活性组分混合物 5％ 10％ 25％ 50％
十二烷基苯磺酸钙 6％ 8％ 6％ 8％
蓖麻油聚乙二醇醚 4％ - 4％ 4％
(36mol氧化乙烯)
辛基苯酚聚乙二醇醚 - 4％ - 2％
(7-8mol氧化乙烯)
环己酮 - - 10％ 20％
芳烃混合物 85％ 78％ 55％ 16％
C9-C12
通过用水稀释，可由这样的乳油获得任意所需浓度的乳剂。
F2.溶液 a) b) c) d)
活性组分混合物 5％ 10％ 50％ 90％
1-甲氧基-3-(3-甲氧基丙氧基)-丙烷 - 20％ 20％ -
聚乙二醇MW 400 20％ 10％ - -
N-甲基-2-吡咯烷酮 - - 30％ 10％
芳烃混合物 75％ 60％ - -
C9-C12
该溶液适于以微滴的形式使用。
F3.可湿性粉剂 a) b) c) d)
活性组分混合物 5％ 25％ 50％ 80％
木质素磺酸钠 4％ - 3％ -
十二烷基硫酸钠 2％ 3％ - 4％
二异丁基萘磺酸钠 - 6％ 5％ 6％
辛基苯酚聚乙二醇醚 - 1％ 2％ -
(7-8mol氧化乙烯)
高度分散的硅酸 1％ 3％ 5％ 10％
高岭土 88％ 62％ 35％ -
将活性组分与助剂充分混合，并将该混合物在合适的研磨机中磨碎，获得了可湿性粉剂，可以用水稀释以获得任意所需浓度的悬浮剂。
F4.包衣粒剂 a) b) c)
活性组分混合物 0.1％ 5％ 15％
高度分散的硅酸 0.9％ 2％ 2％
无机载体 99.0％ 93％ 83％
(φ0.1-1mm)
例如CaCO3或SiO2
将活性组分溶解在二氯甲烷中，通过喷雾施加到载体上，然后将溶剂真空蒸发。
F5.包衣粒剂 a) b) c)
活性组分混合物 0.1％ 5％ 15％
聚乙二醇MW 200 1.0％ 2％ 3％
高度分散的硅酸 0.9％ 1％ 2％
无机载体 98.0％ 92％ 80％
(φ0.1-1mm)
例如CaCO3或SiO2
在混合器中将细研磨的活性组分均匀地施加到用聚乙二醇润湿的载体上。以该方式获得了无粉尘的包衣粒剂。
F6.挤出粒剂 a) b) c) d)
活性组分混合物 0.1％ 3％ 5％ 15％
木质素磺酸钠 1.5％ 2％ 3％ 4％
羧甲基纤维素 1.4％ 2％ 2％ 2％
高岭土 97.0％ 93％ 90％ 79％
将活性组分混合，与助剂研磨，用水将该混合物润温。将该混合物挤出，然后在气流中干燥。
F7.粉剂 a) b) c)
活性组分混合物 0.1％ 1％ 5％
滑石粉 39.9％ 49％ 35％
高岭土 60.0％ 50％ 60％
即用型粉尘剂是通过将活性组分与载体混合、并将混合物在合适的研磨机中研磨而获得的。
F8.胶悬剂 a) b) c) d)
活性组分混合物 3％ 10％ 25％ 50％
乙二醇 5％ 5％ 5％ 5％
壬基苯酚聚乙二醇醚 - 1％ 2％ -
(15mol氧化乙烯)
木质素磺酸钠 3％ 3％ 4％ 5％
羧甲基纤维素 1％ 1％ 1％ 1％
37％甲醛水溶液 0.2％ 0.2％ 0.2％ 0.2％
硅油乳液 0.8％ 0.8％ 0.8％ 0.8％
水 87％ 79％ 62％ 38％
将细研磨的活性组分与助剂充分混合，获得了胶悬剂，通过用水稀释可由其获得任意所需浓度的悬浮液。
实际上更经常将式I化合物与式2.1-2.51混合伴侣单独配制，临用前在施用器中将其以所需混合比例以“桶混”的形式混合在一起。
生物实施例：
当式I与2.1-2.51化合物的活性组分组合的作用大于单独施用的活性组分的作用之和时，即存在协同作用。
对于给定的两种除草剂组合，预计的除草作用We可如下计算(参见COLBY，S.R.，″计算除草剂组合的协同和拮抗反应″，《杂草》(Weeds)15，p.20-22，1967)：
We＝X+[Y·(100-X)/100]
其中：
X＝与未处理的对照(＝0％)相比，在用式I化合物以p kg/公顷的施用量处理时的除草作用百分比。
Y＝与未处理的对照相比，在用式2.1-2.51化合物以q kg/公顷的施用量处理时的除草作用百分比。
We＝在用式I和2.1-2.51化合物以p+q kg/公顷的施用量处理后，预计的除草作用(与未处理的对照相比，除草作用百分比)。
当实际上观测到的作用大于预计的We的值时，即存在协同作用。
在下列实施例中证实了式I化合物与式2.1-2.51化合物的组合的协同作用。
实验描述-芽前测试：
将塑料盆内的标准土壤中播种单子叶和双子叶测试植物。播种后，立即通过喷雾施用水悬浮液形式的测试物(500升水/ha)。施用量取决于在大田条件和温室条件下确定的最适剂量。然后让测试植物在温室中于最适条件下生长。36天后评价测试(％作用，100％＝植物已经死亡，0％＝没有植物毒害作用)。本发明组合物的协同作用的实例如下表B1-B6所示：
混合物A含有915g/升式2.2a化合物和45g/升式3.1化合物作为活性组分。
表B1：
| 测试植物： | 化合物1.001[25g/ha] | 混合物A[900g/ha] | 化合物1.001[25g/ha]+混合物A[900g/ha] | 依据Colby的We |
| 高粱 | 30 | 20 | 90 | 44 |
| 藜 | 0 | 0 | 100 | 0 |
| 黄花稔 | 0 | 70 | 100 | 70 |
表B2：
| 测试植物： | 化合物1.001[12.5g/ha] | 混合物A[900g/ha] | 化合物1.001[12.5g/ha]+混合物A[900g/ha] | 依据Colby的We |
| 高粱 | 0 | 20 | 80 | 20 |
| 藜 | 0 | 0 | 95 | 0 |
| 黄花稔 | 0 | 70 | 95 | 70 |
表B3：
| 测试植物： | 化合物1.001[6.25g/ha] | 混合物A[900g/ha] | 化合物1.001[6.25g/ha]+混合物A[900g/ha] | 依据Colby的We |
| 高粱 | 0 | 20 | 70 | 20 |
| 藜 | 0 | 0 | 95 | 0 |
| 黄花稔 | 0 | 70 | 95 | 70 |
表B4：
| 测试植物： | 化合物1.001[25g/ha] | 混合物A[300g/ha] | 化合物1.001[25g/ha]+混合物A[300g/ha] | 依据Colby的We |
| 藜 | 0 | 0 | 90 | 0 |
| 番薯 | 30 | 0 | 100 | 30 |
| 黄花稔 | 0 | 0 | 40 | 0 |
表B5：
| 测试植物： | 化合物1.001[12.5g/ha] | 混合物A[300g/ha] | 化合物1.001[12.5g/ha]+混合物A[300g/ha] | 依据Colby的We |
| 藜 | 0 | 0 | 80 | 0 |
| 番薯 | 0 | 0 | 60 | 0 |
| 黄花稔 | 0 | 0 | 40 | 0 |
表B6：
| 测试植物： | 化合物1.001[6.25g/ha] | 混合物A[300g/ha] | 化合物1.001[6.25g/ha]+混合物A[300g/ha] | 依据Colby的We |
| 藜 | 0 | 0 | 80 | 0 |
| 番薯 | 0 | 0 | 60 | 0 |
| 黄花稔 | 0 | 0 | 40 | 0 |
实验描述-苗后测试：
将测试植物在塑料盆中于温室条件下生长至2-叶-3-叶期。使用标准土壤作为栽培基质。在2-叶-3-叶期，将除草剂以自身的形式并作为混合物施加到测试植物上。施加是用测试物在500升水/ha中的水悬浮液进行的。施用量取决于在大田条件和温室条件下确定的最适剂量。33天后评价测试(％作用，100％＝植物已经死亡，0％＝没有植物毒害作用)。本发明组合物的协同作用的实例如下表B7-B10所示：
混合物A含有915g/升式2.2a化合物和45g/升式3.1化合物作为活性组分。
表B7：苗后测试：
| 测试植物： | 化合物1.001[12.5g/ha] | 混合物A[900g/ha] | 化合物1.001[12.5g/ha]+混合物A[900g/ha] | 依据Colby的We |
| 番薯 | 0 | 0 | 80 | 0 |
| 蓼 | 0 | 20 | 100 | 20 |
| 苍耳 | 80 | 0 | 100 | 80 |
表B8：苗后测试：
| 测试植物： | 化合物1.001[12.5g/ha] | 混合物A[300g/ha] | 化合物1.001[12.5g/ha]+混合物A[300g/ha] | 依据Colby的We |
| 番薯 | 0 | 0 | 80 | 0 |
| 蓼 | 0 | 0 | 70 | 0 |
| 苍耳 | 80 | 0 | 98 | 80 |
表B9：苗后测试：
| 测试植物： | 化合物1.001[6.25g/ha] | 混合物A[900g/ha] | 化合物1.001[6.25g/ha]+混合物A[900g/ha] | 依据Colby的We |
| 番薯 | 0 | 0 | 70 | 0 |
| 蓼 | 0 | 20 | 70 | 20 |
| 苍耳 | 70 | 0 | 80 | 70 |
表B10：苗后测试：
| 测试植物： | 化合物1.001[6.25g/ha] | 混合物A[300g/ha] | 化合物1.001[6.25g/ha]+混合物A[300g/ha] | 依据Colby的We |
| 番薯 | 0 | 0 | 80 | 0 |
| 蓼 | 0 | 0 | 70 | 0 |
| 苍耳 | 70 | 0 | 70 | 70 |
在下表中，是在14天后进行评价：
表B11：芽前作用：
| 测试植物： | 化合物E8[50g/ha] | 化合物2.18[500g/ha] | 化合物E8[50g/ha]+化合物2.18[500g/ha] | 依据Colby的We |
| 蓼 | 50 | 80 | 95 | 90 |
表B12：芽前作用：
| 测试植物： | 化合物E8[100g/ha] | 化合物2.14[250g/ha] | 化合物E8[100g/ha]+化合物2.14[250g/ha] | 依据Colby的We |
| 蓼 | 50 | 50 | 90 | 75 |
表B13：芽前作用：
| 测试植物： | 化合物E8[100g/ha] | 化合物2.14[125g/ha] | 化合物E8[100g/ha]+化合物2.14[125g/ha] | 依据Colby的We |
| 蓼 | 50 | 30 | 90 | 65 |
表B14：芽前作用：化合物2.13a相当于这样的式2.13化合物，其中R74是-CH2CH2CF3，Y1、Y2、Y3和Y4各是次甲基，Y5是氮，且Y6是甲基。
| 测试植物： | 化合物E8[100g/ha] | 化合物2.13a[60g/ha] | 化合物E8[100g/ha]+化合物2.13a[60g/ha] | 依据Colby的We |
| 蓼 | 50 | 80 | 95 | 90 |
表B15：芽前作用：
| 测试植物： | 化合物E8[50g/ha] | 化合物2.30[60g/ha] | 化合物E8[50g/ha]+化合物2.30[60g/ha] | 依据Colby的We |
| 蓼 | 50 | 30 | 90 | 65 |
表B16：芽前作用：
| 测试植物： | 化合物E8[50g/ha] | 化合物2.21[30g/ha] | 化合物E8[50g/ha]+化合物2.21[30g/ha] | 依据Colby的We |
| 蓼 | 50 | 50 | 100 | 75 |
表B17：芽前作用：化合物2.4.a相当于其中R57是氯、R58是乙基、且R59是叔丁基的式2.4化合物。
| 测试植物： | 化合物E8[50g/ha] | 化合物2.4.a[125g/ha] | 化合物E8[50g/ha]+化合物2.4.a[125g/ha] | 依据Colby的We |
| 蓼 | 50 | 30 | 85 | 65 |
表B18：芽前作用：
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.2.b[300g/ha] | 化合物1.001[25g/ha]+化合物2.2.b[300g/ha] | 依据Colby的We |
| 藜 | 80 | 0 | 95 | 80 |
| 茄 | 80 | 40 | 98 | 88 |
| 莎草 | 0 | 0 | 50 | 0 |
表B19：芽前作用：
化合物2.3.a相当于其中R56是CH(Me)-CH2OMe的式2.3化合物。
| 测试植物： | 化合物1.001[12.5g/ha] | 化合物2.3.a[100g/ha] | 化合物1.001[12.5g/ha]+化合物2.3.a[100g/ha] | 依据Colby的We |
| 藜 | 80 | 20 | 90 | 84 |
| 茄 | 75 | 60 | 90 | 90 |
| 莎草 | 0 | 20 | 60 | 20 |
表B20：芽前作用：
化合物2.2.c相当于其中R53和R54是乙基，且R55是CH2OMe的式2.2化合物。
| 测试植物： | 化合物1.001[12.5g/ha] | 化合物2.2.c[100g/ha] | 化合物1.001[12.5g/ha]+化合物2.2.c[100g/ha] | 依据Colby的We |
| 藜 | 80 | 20 | 90 | 84 |
| 茄 | 75 | 50 | 95 | 88 |
| 莎草 | 0 | 0 | 30 | 0 |
表B21：芽前作用：
化合物2.2.d相当于其中R53是乙基、R54是甲基、且R55是CH2O-CH2CH3的式2.2化合物。
| 测试植物： | 化合物1.001[12.5g/ha] | 化合物2.2.d[100g/ha] | 化合物1.001[12.5g/ha]+化合物2.2.d[100g/ha] | 依据Colby的We |
| 茄 | 75 | 60 | 95 | 90 |
表B22：芽前作用：
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.30[100g/ha] | 化合物1.001[25g/ha]+化合物2.30[100g/ha] | 依据Colby的We |
| 莎草 | 10 | 0 | 60 | 10 |
在下表中，是在31天后进行评价：
表B23：芽前作用：化合物2.4.a相当于其中R57是氯、R58是乙基、且R59是异丙基的式2.4化合物。
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.4.a[250g/ha] | 化合物1.001[25g/ha]+化合物2.4.a[250g/ha] | 依据Colby的We |
| 蓼 | 0 | 20 | 80 | 20 |
表B24：芽前作用：化合物2.4.b相当于其中R57是氯、R58是乙基、且R59是乙基的式2.4化合物。
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.4.b[125g/ha] | 化合物1.001[25g/ha]+化合物2.4.b[125g/ha] | 依据Colby的We |
| 蓼 | 0 | 0 | 40 | 0 |
表B25：芽前作用：化合物2.4.c相当于其中R57是氯、R58是乙基、且R59是叔丁基的式2.4化合物。
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.4.c[250g/ha] | 化合物1.001[25g/ha]+化合物2.4.c[250g/ha] | 依据Colby的We |
| 番薯 | 70 | 0 | 90 | 70 |
| 苍耳 | 80 | 0 | 100 | 80 |
表B26：芽前作用：化合物2.4.d相当于其中R57是甲硫基、R58是乙基、且R59是叔丁基的式2.4化合物。
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.4.d[250g/ha] | 化合物1.001[25g/ha]+化合物2.4.d[250g/ha] | 依据Colby的We |
| 番薯 | 70 | 0 | 80 | 70 |
| 苍耳 | 80 | 10 | 95 | 82 |
表B27：芽前作用：
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.14[125g/ha] | 化合物1.001[25g/ha]+化合物2.14[125g/ha] | 依据Colby的We |
| 番薯 | 70 | 0 | 85 | 70 |
| 苍耳 | 80 | 20 | 100 | 84 |
表B28：芽前作用：化合物2.6.a相当于这样的式2.6化合物，其中R62是氢、R63是甲基、R64是氟、R65是氢、Y是氮、Z是次甲基、且R66是氟。
| 测试植物： | 化合物1.001[50g/ha] | 化合物2.6.a[30g/ha] | 化合物1.001[50g/ha]+化合物2.6.a[30g/ha] | 依据Colby的We |
| 蓼 | 0 | 30 | 90 | 30 |
在下表中，是在21天后进行评价。
表B29：苗后作用：化合物2.7.a相当于其中R67是-C(O)-S-正辛基的式2.7化合物。
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.7.a[250g/ha] | 化合物1.001[25g/ha]+化合物2.7.a[250g/ha] | 依据Colby的We |
| 番薯 | 30 | 10 | 80 | 30 |
| 蓼 | 75 | 0 | 95 | 75 |
| 苍耳 | 90 | 10 | 100 | 91 |
表B30：苗后作用：
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.19[250g/ha] | 化合物1.001[25g/ha]+化合物2.19[250g/ha] | 依据Colby的We |
| 番薯 | 30 | 60 | 95 | 72 |
表B31：苗后作用：
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.16[360g/ha] | 化合物1.001[25g/ha]+化合物2.16[360g/ha] | 依据Colby的We |
| 番薯 | 30 | 20 | 70 | 46 |
| 蓼 | 75 | 10 | 90 | 84 |
表B32：苗后作用：
| 测试植物： | 化合物1.001[12.5g/ha] | 化合物2.33[360g/ha] | 化合物1.001[12.5g/ha]+化合物2.33[360g/ha] | 依据Colby的We |
| 蓼 | 30 | 0 | 90 | 30 |
表B33：苗后作用：化合物2.12.a相当于其中R73是NH2的式2.12化合物。
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.12.a[400g/ha] | 化合物1.001[25g/ha]+化合物2.33.a[400g/ha] | 依据Colby的We |
| 番薯 | 30 | 20 | 90 | 44 |
表B34：苗后作用：
| 测试植物： | 化合物1.001[12.5g/ha] | 化合物2.25[2g/ha] | 化合物1.001[12.5g/ha]+化合物2.25[2g/ha] | 依据Colby的We |
| 番薯 | 30 | 0 | 50 | 30 |
| 蓼 | 30 | 0 | 40 | 30 |
表B35：苗后作用：化合物2.1.a相当于其中R52是氢、且R51是乙基的式2.1化合物。
| 测试植物： | 化合物1.001[12.5g/ha] | 化合物2.1.a[30g/ha] | 化合物1.001[12.5g/ha]+化合物2.1.a[30g/ha] | 依据Colby的We |
| 蓼 | 30 | 30 | 70 | 51 |
表B36：苗后作用：化合物2.1.b相当于其中R51是CH20Me、且R52是氢的式2.1化合物。
| 测试植物： | 化合物1.001[25g/ha] | 化合物2.1.b[30g/ha] | 化合物1.001[25g/ha]+化合物2.1.b[30g/ha] | 依据Colby的We |
| 蓼 | 75 | 30 | 90 | 83 |
在下表中，是在23天后进行评价：
表B37：芽前作用：化合物2.13.b相当于这样的式2.13化合物，其中R74是-COOMe，Y1、Y2、Y3和Y4各是次甲基，Y5是次甲基，且Y6和Y7是二氟甲氧基。
| 测试植物： | 化合物1.001[6g/ha] | 化合物2.13.b[15g/ha] | 化合物1.001[6g/ha]+化合物2.13.b[15g/ha] | 依据Colby的We |
| 藜 | 50 | 70 | 95 | 85 |
表B38：芽前作用：
| 测试植物： | 化合物1.001[6g/ha] | 化合物2.13.c[60g/ha] | 化合物1.001[6g/ha]+化合物2.13.c[60g/ha] | 依据Colby的We |
| 藜 | 50 | 10 | 85 | 55 |
表B39：芽前作用：化合物2.13.d相当于这样的式2.13化合物，其中Y1、Y2、Y3和Y4是次甲基，R74是三氟甲基，Y5是氮，Y6是三氟甲基，且Y7是甲氧基。
| 测试植物： | 化合物1.001[6g/ha] | 化合物2.13.d[7.5g/ha] | 化合物1.001[6g/ha]+化合物2.13.d[7.5g/ha] | 依据Colby的We |
| 苋 | 10 | 80 | 95 | 82 |
已经令人惊奇地表明，特定的安全剂适于和本发明协同组合物混合。因此，本发明还涉及用于控制有用植物农作物、尤其是玉米农作物中的禾草和杂草的选择性除草组合物，所述组合物包含式I化合物、一种或多种选自式2.1-2.51化合物的化合物、和安全剂(对抗剂、解毒剂)，所述组合物保护有用植物、但是不保护杂草，并对抗除草剂的植物毒害作用，以及这样的组合物在控制有用植物中的杂草中的应用。
本发明还提供了选择性除草组合物，所述组合物除了包含常用惰性制剂助剂例如载体、溶剂和润湿剂以外，还包含下列组分的混合物作为活性组分：
a)除草协同有效量的式I化合物和一种或多种选自式2.1-2.51化合物的化合物，和
b)除草拮抗有效量的选自下列的化合物：
式3.1化合物
和式3.2化合物
和式3.3化合物
和式3.4化合物
和式3.5化合物
和式3.6化合物
和式3.7化合物
和式3.8化合物
和式3.9化合物
Cl2CHCON(CH2CH＝CH2)2(3.9)，
和式3.10化合物
和式3.11化合物
和式3.12化合物
和式3.13化合物
和式3.14化合物
和式3.15化合物
和式3.16化合物
本发明还提供了选择性除草组合物，所述组合物除了包含常用惰性制剂助剂例如载体、溶剂和润湿剂以外，还包含下列组分的混合物作为活性组分：
a)除草有效量的式I化合物，和
b)除草拮抗有效量的选自式3.1、3.2、3.3、3.4、3.5、3.6、3.7、3.8、3.9、3.10、3.11、3.12、3.1 3、3.14、3.15和3.16化合物的化合物。
优选的本发明组合物包含选自式3.1、3.3和3.8化合物的化合物作为安全剂。这样安全剂尤其适用于包含上述优选的式I化合物和任选的式2.1-2.51化合物的本发明组合物。
已经表明，式I化合物与式3.1化合物的组合是特别有效的组合物，化合物1.001是特别优选的式I化合物。该组合物优选与式2.2a化合物一起使用
(2.2a，aRS，1’S(-)N-(1’-甲基-2’-甲氧基乙基)-N-氯乙酰基-2-乙基-6-甲基苯胺)。
本发明还涉及选择性地控制有用植物农作物中的杂草的方法，所述方法包括用除草有效量的式I除草剂、视情况而定的一种或多种选自式2.1-2.51化合物的除草剂、和除草拮抗有效量的式3.1-3.16安全剂来处理有用植物、种子或其切条、或其耕作区域。
式3.1-3.16化合物是已知的，并描述在例如《农药手册》，第11版，英国作物保护委员会，1997中，条目号为61(式3.1，解草嗪)、304(式3.2，解草啶)、154(式3.3，解草酯)、462(式3.4，吡咯解草酯)、377(式3.5，解草恶唑)、363(式3.8，氟草肟)、213(式3.9，烯丙酰草胺)和350(式3.10，解草胺)。式3.11化合物的名称是MON 4660(Monsanto)，并描述在例如EP-A-0 436 483中。
式3.6化合物(AC 304 415)描述在例如EP-A-0 613 618中，式3.7化合物描述在DE-A-2 948 535中。式3.12化合物描述在DE-A-4 331 448中，式3.13化合物描述在DE-A-3 525 205中。式3.14化合物是已知的，描述在例如US-A-5 215 570中，式3.15化合物描述在例如EP-A-0 929543中。式3.16化合物描述在WO 99/00020中。除了式3.16化合物以外，描述在WO 99/00020中的其它3-(5-四唑基-羰基)-2-喹诺酮，尤其是在第21-29页的表1和2中具体公开的化合物也适于保护农作物植物抗式I化合物的植物毒害作用。
作为可通过式3.1-3.16安全剂拮抗上述除草剂损害作用而得以保护的农作物植物，可尤其提及的有禾谷类植物、棉花、大豆、甜菜、甘蔗、种植园农作物、油菜、玉米和稻，更尤其是玉米。“农作物”还指通过常规育种或基因工程方法使其对除草剂或除草剂类别耐受的农作物。
欲控制的杂草既可以是单子叶杂草，也可以是双子叶杂草，例如繁缕属、剪股颖属、马唐属、燕麦属、阿披拉草属、臂形草属、虉草属、狗尾草属、芥属、毒麦属、茄属、稗属、藨草属、雨久花属、慈菇属、黍属、雀麦属、看麦娘属、石茅高梁、双色高梁、筒轴茅属、莎草属、苘麻属、黄花稔属、苍耳属、苋属、藜属、番薯属、苘蒿属、猪殃殃属、堇菜属和婆婆纳属。
耕作区域包括农作物植物已经生长或者已经将这些农作物植物的种子播种的土地区域，以及准备用这样的农作物植物耕作的土地。
根据预期应用，式3.1-3.16安全剂可以在农作物植物种子的预处理中使用(种子或切条的包衣)，或者可以在播种前或播种后引入到土壤中。然而，其可以在植物出芽后单独施用或者与除草剂一起施用。因此，用安全剂处理植物或种子一般可以在独立于施用除草剂的时间进行。然而，也可以通过同时施用除草剂和安全剂(例如以桶混的形式)来处理植物。安全剂的施用量与除草剂的施用量的比例主要取决于施用方法。对于通过使用包含安全剂和除草剂的组合的桶混物或者通过单独施用安全剂和除草剂来进行的大田处理，除草剂与安全剂的比例一般为100∶1-1∶10、优选20∶1-1∶1。对于大田处理，通常施用0.001-0.5千克安全剂/公顷、优选0.001-0.25千克安全剂/公顷。
除草剂的施用量一般为0.001-5kg/ha，但是优选为0.005-0.5kg/ha。
本发明组合物适用于农业中的所有常用方法，例如芽前施用、苗后施用和种子包衣。
对于种子包衣，一般施用0.001-10g安全剂/kg种子、优选0.05-2g安全剂/kg种子。当在播种前不久安全剂以液体形式通过浸泡施用时，有利起见，所用的安全剂溶液含有浓度为1-10 000ppm、优选为100-1000ppm的安全剂。
为了施用，有利起见，将式3.1-3.16安全剂或者这些安全剂与式I除草剂以及视情况而定的一种或多种选自式2.1-2.51的除草剂的组合与制剂技术中的常用制剂一起加工配制，例如配制成乳油、可包衣糊剂、可直接喷雾或稀释的溶液、可湿性粉剂、可溶性粉剂、粉剂、粒剂或微胶囊。
这样的制剂描述在例如WO 97/34485第9-13页中。制剂是以自身已知的方式制得的，例如通过将活性组分与制剂助剂例如溶剂或固体载体充分混合和/或研磨而制得。此外，在制剂的制备中可使用表面活性化合物(表面活性剂)。溶剂和固体载体的实例描述在例如WO 97/34485第6页中。
根据欲配制的式I、2.1-2.51和3.1-3.16化合物的性质，可使用的表面活性化合物是具有良好乳化、分散和润湿性质的非离子、阳离子和/或阴离子表面活性剂以及表面活性剂混合物。合适的阴离子、非离子和阳离子表面活性剂描述在例如WO 97/34485第7和8页中。制剂技术常用的表面活性剂也适用于本发明除草组合物的制备，这些表面活性剂特别描述在《McCutcheon洗涤剂和乳化剂年鉴》″McCutcheon’s Detergentsand Emulsifiers Annual″MC Publishing Corp.，Ridgewood New Jersey，1981，Stache，H.，″Tensid-Taschenbuch″，Carl Hanser Verlag，Munich/Nienna，1981和M.and J.Ash，《表面活性剂大全》(″Encyclopedia of Surfactants″)，Vol 1-111，Chemical PublishingCo.，New York，1980-81中。
除草制剂通常含有0.1-99％重量、尤其是0.1-95％重量的包含式I化合物、选自式2.1-2.51化合物的化合物、和式3.1-3.16化合物的活性组分混合物，1-99.9％重量的固体或液体制剂助剂，和0-25％重量、尤其是0.1-25％重量的表面活性剂。然而，市售产品一般是配制成浓缩物，最终的使用者通常使用稀释的制剂。
组合物还可以含有其它组分，例如稳定剂如植物油或环氧化植物油(环氧化椰子油、菜籽油或豆油)，消泡剂例如硅油，防腐剂，粘度调节剂，粘合剂，增粘剂，以及肥料和其它活性组分。在保护植物以对抗式I和2.1-2.51除草剂的损害作用的过程中，为了使用式3.1-3.16安全剂或包含它们的组合物，可使用多种不同的方法和技术，例如下列：
i)种子包衣
a)通过在容器中振摇用式3.1-3.16化合物的可湿性粉剂将种子包衣，直至粉剂在种子表面上分布均匀(干法包衣)。在该方法中，每100kg种子使用大约1-500g式3.1-3.16化合物(4g-2kg可湿性粉剂)。
b)按照a)的方法，用式3.1-3.16化合物的乳油将种子包衣(湿法包衣)。
c)通过将种子在含有100-1000ppm式3.1-3.16化合物的液体中浸泡1-72小时，然后任选将种子干燥来进行包衣(浸泡包衣)。
给种子包衣或处理发芽的幼苗是优选的施用方法，因为用活性组分处理完全是针对目标农作物。通常每100kg种子使用1-1000g解毒剂、优选5-250g解毒剂，但是根据使得能够还加入其它组分或微量营养素的方法，该浓度限度可向上或向下改变(重复包衣)。
ii)作为桶混物施用
使用解毒剂与除草剂的混合物(二者的重量比为10∶1-1∶100)的液体制剂，除草剂的施用量为0.005-5.0kg/公顷。这样的桶混物在播种之前或之后施用。
iii)施用到播沟中
将式3.1-3.16混合物以乳油、可湿性粉剂或粒剂的形式施加到开放的播种种子的犁沟内。一旦种子犁沟已覆盖，即以常规方式采用芽前法施用除草剂。
iv)控制活性组分的释放
将在溶液中的式3.1-3.16化合物施加到无机物载体或聚合颗粒(尿素/甲醛)上，并干燥。如果需要的话，还可以施加上使得活性组分在特定时间内以计量的量释放的包衣(包衣粒剂)。
优选的制剂尤其具有下列组成：
(％＝重量百分比)
乳油：
活性组分混合物：1-90％、优选5-20％
表面活性剂： 1-30％、优选10-20％
液体载体： 5-94％、优选70-85％
粉剂：
活性组分混合物：0.1-10％、优选0.1-5％
固体载体： 99.9-90％、优选99.9-99％
胶悬剂：
活性组分混合物：5-75％、优选10-50％
水： 94-24％、优选88-30％
表面活性剂： 1-40％、优选2-30％
可湿性粉剂：
活性组分混合物：0.5-90％、优选1-80％
表面活性剂： 0.5-20％、优选1-15％
固体载体： 5-95％、优选15-90％
粒剂：
活性组分混合物：0.1-30％、优选0.1-15％
固体载体： 99.5-70％、优选97-85％
下列实施例进一步举例说明了本发明，但不是限制本发明。
式I除草剂、任选的式2.1-2.51除草剂、和式3.1-3.16安全剂的混合物的制剂实施例(％＝重量百分比)
F1.乳油 a) b) c) d)
活性组分混合物 5％ 10％ 25％ 50％
十二烷基苯磺酸钙 6％ 8％ 6％ 8％
蓖麻油聚乙二醇醚 4％ - 4％ 4％
(36mol氧化乙烯)
辛基苯酚聚乙二醇醚 - 4％ - 2％
(7-8mol氧化乙烯)
环己酮 - - 10％ 20％
芳烃混合物 85％ 78％ 55％ 16％
C9-C12
通过用水稀释，可由这样的乳油获得任意所需浓度的乳剂。
F2.溶液 a) b) c) d)
活性组分混合物 5％ 10％ 50％ 90％
1-甲氧基-3-(3-甲氧基- - 20％ 20％ -
丙氧基)-丙烷
聚乙二醇MW 400 20％ 10％ - -
N-甲基-2-吡咯烷酮 - - 30％ 10％
芳烃混合物 75％ 60％ - -
C9-C12
该溶液适于以微滴的形式使用。
F3.可湿性粉剂 a) b) c) d)
活性组分混合物 5％ 25％ 50％ 80％
木质素磺酸钠 4％ - 3％ -
十二烷基硫酸钠 2％ 3％ - 4％
二异丁基萘磺酸钠 - 6％ 5％ 6％
辛基苯酚聚乙二醇醚 - 1％ 2％ -
(7-8mol氧化乙烯)
高度分散的硅酸 1％ 3％ 5％ 10％
高岭土 88％ 62％ 35％ -
将活性组分与助剂充分混合，并将该混合物在合适的研磨机中磨碎，获得了可湿性粉剂，可以用水稀释以获得任意所需浓度的悬浮剂。
F4.包衣粒剂 a) b) c)
活性组分混合物 0.1％ 5％ 15％
高度分散的硅酸 0.9％ 2％ 2％
无机载体 99.0％ 93％ 83％
(φ0.1-1 mm)
例如CaCO3或SiO2
将活性组分溶解在二氯甲烷中，通过喷雾施加到载体上，然后将溶剂真空蒸发。
F5.包衣粒剂 a) b) c)
活性组分混合物 0.1％ 5％ 15％
聚乙二醇MW 200 1.0％ 2％ 3％
高度分散的硅酸 0.9％ 1％ 2％
无机载体 98.0％ 92％ 80％
(φ0.1-1mm)
例如CaCO3或Si02
在混合器中将细研磨的活性组分均匀地施加到用聚乙二醇润湿的载体上。以该方式获得了无粉尘的包衣粒剂。
F6.挤出粒剂 a) b) c) d)
活性组分混合物 0.1％ 3％ 5％ 15％
木质素磺酸钠 1.5％ 2％ 3％ 4％
羧甲基纤维素 1.4％ 2％ 2％ 2％
高岭土 97.0％ 93％ 90％ 79％
将活性组分混合，与助剂研磨，用水将该混合物润湿。将该混合物挤出，然后在气流中干燥。
F7.粉尘剂 a) b) c)
活性组分混合物 0.1％ 1％ 5％
滑石粉 39.9％ 49％ 35％
高岭土 60.0％ 50％ 60％
即用型粉尘剂是通过将活性组分与载体混合、并将混合物在合适的研磨机中研磨而获得的。
F8.胶悬剂 a) b) c) d)
活性组分混合物 3％ 10％ 25％ 50％
乙二醇 5％ 5％ 5％ 5％
壬基苯酚聚乙二醇醚 - 1％ 2％ -
(15mol氧化乙烯)
木质素磺酸钠 3％ 3％ 4％ 5％
羧甲基纤维素 1％ 1％ 1％ 1％
37％甲醛水溶液 0.2％ 0.2％ 0.2％ 0.2％
硅油乳液 0.8％ 0.8％ 0.8％ 0.8％
水 87％ 79％ 62％ 38％
将细研磨的活性组分与助剂充分混合，获得了胶悬剂，通过用水稀释可由其获得任意所需浓度的悬浮液。
实际上更经常将式I化合物、式2.1-2.51化合物和式3.1-3.16化合物单独配制，临用前在施用器中将其以所需混合比例以“桶混”的形式混合在一起。
下列实施例举例说明了式3.1-3.16安全剂保护农作物植物对抗式I除草剂的植物毒害作用的能力。
生物实施例：安全作用
将测试植物在塑料盆中于温室条件下生长至4-叶期。在该阶段将单独的除草剂、除草剂与作为安全剂测试的化合物的混合物施加到测试植物上。以用500升水/公顷由25％可湿性粉剂(实施例F3，b)制得的测试化合物的水悬浮液的形式施用。施用4周后，使用百分比标度评价除草剂对农作物植物例如玉米和禾谷类植物的毒害作用，100％是指测试植物已经死亡，0％是指没有任何植物毒害作用。
在该测试中获得的结果证实了式3.1-3.16化合物可显著减轻由式I除草剂与一种或多种式2.1-2.51除草剂的组合所引起的农作物植物损害。安全作用的实例如下表B40所示：
表B40：
| 测试植物 | 化合物1.001[50g/ha] | 化合物1.001[50g/ha]+化合物3.3[50g/ha] | 化合物1.001[50g/ha]+化合物3.1[50g/ha] | 化合物1.001[50g/ha]+化合物3.8[50g/ha] |
| 玉米 | 50 | 5 | 5 | 0 |
| 苘麻 | 100 | 100 | 100 | 100 |
| 狗尾草 | 100 | 100 | 100 | 100 |
当依据实施例F1、F2和F4-F8配制混合物时，获得了相同结果。
Claims (4)
1.选择性除草组合物，所述组合物除了含有常规惰性制剂助剂以外，还含有下列组分的混合物作为活性组分：
a)除草有效量的式Ia化合物或其农业可接受盐
R48是C1-C6烷基、C2-C6链烯基、C2-C6卤代链烯基、C2-C6炔基、C2-C6卤代炔基、C3-C6环烷基、C1-C6卤代烷基或-CH2OCH2CH2OCH3；
R49是氢；
R50是C1-C6卤代烷基；以及
Q是基团Q2
其中R23是羟基；且
Y是氧、硫、化学键或C1-C4亚烷基桥；
和
b)协同有效量的式
式2.14化合物
2.控制有用植物农作物中不希望的植物生长的方法，所述方法包括将除草有效量的权利要求1的组合物作用于农作物植物或其场所。
3.权利要求2的方法，其中所述农作物植物是玉米或甘蔗。
4.权利要求2的方法，其中用所述组合物以相当于1-5000g活性组分/公顷总量的施用量处理有用植物农作物。
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