CN1899483A - Healing type bore regenerating pill and preparing method - Google Patents

Abstract

The present invention belongs to the field of medicine, and is one Chinese herbal medicine prepared through unique preparation process. The healing type bone regenerating pill can regulate body's endocrine function, speed the growth hormone secretion of antierior pituitary, promote the separation of healed skeleton line, improve body's metabolism, provide trace elements essential for body's growth and promote body's second time growth, so as to reach the aim of treating microsoma. The Chinese herbal medicine of the present invention is used mainly for treating endocrine diseases, dwarfism and cretinism, and has obvious curative effect on teenagers below 28 years old.

Description

Healing type bore regenerating pill and preparation method

The present invention is the skeleton regeneration Chinese medicine preparation of pure natural prepared from traditional Chinese medicines, belong to medicine and make category, the normal development of human body is related to human physique and high-quality life mileage, because all multifactor adult male heights that cause such as heredity, disease, nutrition are lower than 1.7m, adult female's height is lower than 1.6m, medically is being referred to as short stature.Usually adopt artificial growth hormone at present, Protropin is treated short stature, but because of it costs an arm and a leg, it is little to adapt to the range of age, and side effect is difficult to apply greatly.And growth hormone discharges chemical agent such as class peptide only to be considered to increase, and when not considering that this external sharp thorn increases, to the influence and the side effect thereof of other health factor among the human development; And increase health product and the food of circulation in the market only are that to improve its effect of renal function unsatisfactory, because the short person is poor kidney not necessarily, the reasonable secretion of hypophysis cerebri growth hormone, the allotment of essence, gas, blood, any one has deviation all can influence human development's growth.

The present invention is according to China's Traditional Chinese medical theory, and medicine is known theoretical, treatment a kind of evident in efficacy, that the have no side effect healing type bore regenerating medicine of short and small stature of invention.The objective of the invention is to develop a kind of natural Chinese medicinal herb prescription that adopts fully, can improve the cerebral nerve active procedure, promote the closure state skeleton line to separate, can improve the organism metabolism process again, nutritions such as the required trace element of human body growth promoter, each seed amino acid and calcium are provided simultaneously, make it when increasing, reach medicine well-balanced, healthy and strong, Fructus Alpiniae Oxyphyllae.

Pharmacological action, the present invention selects for use has invigorating spleen and reinforcing stomach, benefiting qi and nourishing blood, invigorating the kidney and strengthening the bones, delay the rare rare Chinese medicine of multi-flavor of skeleton line closure, can fully regulate the human body endocrine function, promote anterior pituitary secretion growth hormone, promote that human body regrows growth, thereby reach treatment purpose of short and small stature.

The present invention cure mainly because of endocrinopathy, dwarfism, cretinism cause of short and small stature, the hypoevolutism type that monophagia, anorexia, malnutrition and inherited genetic factors, Nervous and Mental Factors, psychological factor cause is of short and small stature.The present invention not only can quicken human body and increase, and can also delay the bone healing time simultaneously, has the effect that increases once more for young crowd below 28 years old.

Pathogenic factor at its short stature.The invention provides the preparation method of three kinds of healing type bore regenerating pills.

One of healing type bore regenerating pill and preparation method are as following:

One of short stature pathogenic factor: because of the of short and small stature and dietetic nutrition that endocrinopathy, dwarfism, cretinism cause bad, stomach poor appetite, insufficiency of the spleen lack of appetite, infantile malnutrition and cause growth retardation.Radix Ginseng (9～11%), ZENGGUCAO (1%～5%), QIMENGHUA (3～7%), Os Draconis (calcined) (5～7%) Rhizoma Dioscoreae (9～11%), Endothelium Corneum Gigeriae Galli (9～11%), Fructus Setariae Germinatus (5～9%), Semen Euryales (8～10%), lotus rice (8～10%), Pericarpium Citri Reticulatae (5～9%) are mixed pulverizing, sieve.Oversize and fevervine (9～11%), Massa Medicata Fermentata (8～10%), Fructus Crataegi (8～10%), add that water is common to be decocted 1～5 time, with 2～3 times be the best, decocting time was a surname with 0.5～3 hour at every turn, was the best with 1 hour.Decoction liquor concentrates the system thick paste.Thick paste 10% and minus sieve 40% thing, starch 50% mixes, granulates, is drying to obtain finished medicines.Fry in shallow oil slag and discard, so promptly extract the fevervine of oversize and fibre rich matter, mould highly seasoned Massa Medicata Fermentata, the water solublity active ingredient in the particle Fructus Crataegi heavily, guaranteed pharmaceutical effectiveness, removed a large amount of medicinal residues again, dwindled dose.

Characteristics of the present invention are to merge each time decoction liquor.The thin slag of filtering is depressed at normal pressure or alkali and to be concentrated, and relative density is 1.2～1.4 to be advisable when being concentrated into 20 °, is the best with relative density 1.3.

Healing type bore regenerating pill and preparation method two as following:

According to two of short stature pathogenic factor: because of the familial gene, Nervous and Mental Factors, psychological factor and the dedicate one's life to material is short and small.For this reason, Semen Juglandis (8.5～11%) squeezing is separated into oils and fats and oil cake, oils and fats device preservation in addition, standby.With Semen Juglandis oil cake, ZENGGUCAO (5～9%), QIMENGHUA (7～10%), Os Draconis (calcined) (5～7%), Radix Codonopsis (8.5～10%), Rhizoma Dioscoreae (9～12%), Poria (9～12%), Radix Rehmanniae Preparata (8.5～11%), Fructus Lycii (8.5～5%), Massa Medicata Fermentata (8.5～11%), mixing, drying, pulverize, sieve.With Ganoderma (17～20%), add entry and be decocted first and boil, add Radix Codonopsis (17～20%), the Radix Astragali (17～20%), Herba Houttuyniae (17～20%), oversize, add decocting again and boil 1～5 time, decocting liquid merges, remove thin slag, under normal pressure or decompression, be condensed into thick paste.Thick paste and minus sieve thing, Semen Juglandis oils and fats, starch mixing granulation are promptly.

Because it is 68% that Semen Juglandis contains oil quantity, mix to pulverize to make whole material be the sticking shape of oil with other medicines, can't sieve.Characteristics of the present invention are that Semen Juglandis is squeezed separately, are separated into oils and fats and oil cake.Oil cake mixes dozen powder and just very easily sieves with other medicine, oils and fats does not sieve directly in the minus sieve thing.

The physiologically active composition of Ganoderma is a polysaccharide.Relatively poor must the decoction water long period of its surface energy affinity big and water could be improved the dissolubility in water.Ganoderma decocts earlier and was a surname in 1～5 hour, and it is best decocting 3 hours.Add Radix Codonopsis, the Radix Astragali, Herba Houttuyniae and oversize and add decocting in water again and be advisable for 1～4 time this moment, and 2 times be best, boils at every turn and be advisable in 0.5～3 hour, and 1.5 hours is the best.

Merge decoction liquor, remove tiny residue, relative density is 1.1～1.5 to be advisable when being concentrated into 20 ° under decompression or normal pressure, and 1.3 be the thick paste of the best.

Thick paste, minus sieve thing, starch are added expressed Semen Juglandis oils and fats in right amount, and mixing granulation is drying to obtain.

Healing type bore regenerating pill and preparation method three as following:

According to three of short stature pathogenic factor: because of growing too early, closed in advance cause of short and small stature of skeleton line need carry out skeleton and separate, and promotes the pituitary hormone secretion.With Semen Juglandis (9～11%), Semen Sesami Nigrum (9～11%), oils and fats, oil cake are isolated in squeezing respectively.Oils and fats device is in addition stored standby, mix oil cake and ZENGGUCAO (7～9%), QIMENGHUA (3～12%), Os Draconis (calcined) (5～15%), Radix Ginseng (1.9～2.1%), Placenta Hominis (1.9～2.1%), Semen Coicis (0.9～1.1%), Rhizoma Dioscoreae (19～21%), Pericarpium Citri Reticulatae (4.5～5.5%), anistree (0.5～1%), drying, pulverizes, sieves.Oversize and Radix Codonopsis (19～21%), Fructus Crataegi (9～11%), mixing and water adding decocts, and decoction liquor is concentrated into thick paste.

Thick paste, minus sieve thing, starch is an amount of, Semen Sesami Nigrum oils and fats, Semen Juglandis oils and fats, mixing, granulate, be drying to obtain.Feature of the present invention is Semen Juglandis, the Semen Sesami Nigrum oils and fats of must squeezing out respectively, and oils and fats directly is used as medicine, and oil cake mixes with other medicine, carries out drying, the processing of pulverizing, sieve.

Another feature of the present invention is that Radix Codonopsis, Fructus Crataegi and oversize decoct with water 1～4 time and be advisable, with 2 times be the best, each 0.5～2 hour was the best with 2 hours.

Another feature of the present invention is that each time decoction liquor is merged, and removes thin slag, and its relative density is 1.1～1.5 to be advisable when being concentrated into 20 ° under decompression or normal pressure, is the thick paste of the best with 1.3.

Adopt the healing type bore regenerating pill of above three kinds of methods preparation, have the bioavailability height, curative effect is certain, does not influence its stone age when promoting short growing in stature, and is easy to store, and dose is little, and the patient is easy to advantages such as acceptance.And have tangible kidney-tonifying and brain tonic, the effect of spleen benefiting and stimulating the appetite provides nutrition to transform to body, can satisfy and improves the cellular metabolism situation, has the effect that excites and transfer the human hormone.Through clinical verification, the effective percentage that uses 6～9 monthly average of medicine of above-mentioned preparation to increase by 5 centimeters to crowd between 22～28 years old be crowd below 85.5%, 22 years old use 5～8 monthly average of medicine of method for preparing increase by 7 centimeters effective percentage be 99.7%.

The ratio of the each component that this case is related is a percetage by weight, and note is made " % ".

The pharmacology of segmentation scheme is among the present invention:

1, contains ginsenoside, panaxynol, panax acid, each seed amino acid and peptide class, glucose, maltose, panose, vitamin B1, B2 in the Radix Ginseng.Wherein ginsenoside, panaxynol, peptide class can be improved the cerebral nerve active procedure, excite the secretion of pituitary growth hormone, promote brain intelligence to grow, each seed amino acid, saccharide, panax acid and vitamin can promote the zymolysis of human body saccharide, improve energy metabolism, promote digestive function, correct the dysbolismus of body nutritional imbalance, thereby the raising body absorption rate has enough nutrition for growth.

2, the Colla Corii Asini Main Ingredients and Appearance is aminoacid, protein and calcium, and blood nourishing function is arranged, and improves calcium balance in the body, increases calcium composition in the blood, makes skeleton that the source of generation be arranged, and reaches the purpose of growing tall.

3, the ZENGGUCAO Main Ingredients and Appearance is a calcium carbonate, calcium phosphate and the no plain zinc of trace, magnesium, ferrum etc., and trace element is that people's bulk-growth is necessary.Particularly these trace element combine with Colla Corii Asini and promote that blood calcium increases, and effectively replenish the bone growth desired substance, reach the purpose of growing tall.

4, Carapax Trionycis contains trace element such as colloid, keratin, iodine, vitamin D, calcium, phosphorus, match with Radix Ginseng and run through human body upper, middle and lower three warmers meridians, replenish the moon of muscle arteries and veins and the gas of sun, one nourishing YIN, a YANG invigorating, one, one are speeded, complement each other, promote body QI and blood smoothness, thereby it is fluent to reach muscles and bones, makes health quicken to grow tall.

5, Os Draconis (calcined) contains the sky, body is grown trace element such as required chlorophyll, free amino acid, leucine, carotene, growth hormone, copper, vitamin A, B, phosphorus, ferrum, zinc, can play invigorate blood circulation, sharp bone effect, match to reach with Colla Corii Asini and nourish blood, moisten bone, regulate human body 12 big meridians, impel osteoarthrosis to bend and stretch flexibly, reach the purpose that joint increases, stature increases.

6, the Poria Main Ingredients and Appearance is lecithin, lipase, protease, pachymic acid, histidine, protein, glucose etc., its energy eliminating dampness by diuresis diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming, playing an important role aspect growing up in height, the lopsided development of correction build, regulate the taste elevating function, make body fully absorb nutrition, the vital essence of the balance vital organs of the human body distributes, and promotes skeletal growth.

7, Endothelium Corneum Gigeriae Galli contains glycoprotein, cysteine, vitamin B1, B2, ascorbic acid, invigorating spleen and reinforcing stomach, facilitating digestion reaches the purpose of hemopoietic, and blood is prosperous then arrogant, the arrogant chemical medicine power of then transporting is more strong, make the adjusting of whole prescription have gas, blood is arranged, bone is arranged, meat is arranged, absorb in vivo, impel the stature balanced growth thereby reach the enhancing medicine.

Advantage of the present invention is to adopt the pure natural Chinese herbal medicine, and monarch is just right, and Radix Ginseng is mended the vigour of human body in the main formula; Carapax Trionycis is solely supported Kidney-Yin, and the negative and positive all things on earth that is harmonious is luxuriant; Colla Corii Asini nourishes blood and enriches blood, and helps the yang blood and qi blending; Concha Ostreae contains the required trace element of human development, the monarch and his subjects' product are introduced positive hall, one answers the lifting of diet digestion passage that rule is arranged, and helps homophony to be distributed in human body altogether, brings into play in the meridians of human body three warmers, moisten the QI and blood of nourishing bone bone, can fully regulate brain time biological clock one strobile, make it to secrete enough growth hormone, can regulate body essence, gas, cylinder again and make it comprehensive cooperation, thereby it is well-balanced to reach when growing tall stalwartness, improves the purpose of brain intelligence.Therefore, the effect of correcting the bodily form and Fructus Alpiniae Oxyphyllae is arranged, without any side effects.

Bound fraction case of the present invention is narrated its outstanding effect: (case is attached)

Show that according to the modern medicine data male 16 years old, 15 years old speed of growth of women begin to slow down, that have even stop to increase, the result of the test of the present invention in crowd below 22 years old shows the effect that very big promotion growth promoter was arranged before 22 years old, between 22～28 years old, also have and increase effect significantly, can correct simultaneously the skeleton crosswise development, promote the effect that brain development and body-building are healthy and strong.This theory origin is in " in the emperor through " flavour of a drug refine, and compatibility is rigorous, and assistant makes clearly demarcated, and curative effect is high, generally take 3 courses of treatment after, health increases 5～8 centimeters in 9 months.

Embodiments of the invention can be made by above three kinds of healing type bore regenerating pills and preparing process.Provide by its composition and proportion technique scheme, be equipped with accessory drugs after effect better, it is edible also to can be made into health product.

Case 1:

20 years old therapeutic purposes of Chen Qiang man: grow tall

The first visit date: on May 28th, 2005; Take medicine the date: on June 1st, 2005 rose

Address: dormitory area, owner building, Site of Qing Hua Yuan, Haidian, Beijing

Predecessor's high detection: 1.67m (detection of light foot) takes medicine

The hobby of the diet sense of taste: peppery salty food mixes

The motion hobby is arranged: basketball, football, wushu (Computer Science and Technology Department of Tsing-Hua University reading now).

Patient's readme: I am higher person in the annual level stature at junior-senior high school period, and once measuring when physical examination is 1.66 meters.Be the short partially person in of the same age now, 1.66 meters heights measuring from senior middle school are nearly all not long more till now later on.Once use height-increasing insole and the product that increase that increase health product and so on, also do not have effect.My mother is afraid of that I have inherited the hereditary short and small of family, and today, the spy was with me to come you to it is desirable to and can obtain medical treatment, and the medicine that is right can not bring sequela to the person because I listen the classmate.

Diagnostic result: build is thin partially, and mother's stature is not high in the family, and it is of short and small stature to belong to heritability

Punishment: 2 courses of treatment of bore regenerating pill, oral one time 4.5 gram (about 25)/day, once a day.

Take 52 days courses of treatment after measure, height reaches 1.69 meters, has a net increase of high more than 2 centimeters.

Continued on August 1st, 2005 and use a course of treatment, measure height on October 2nd, 2005 and reach: 1.73m (rice).

Case 2:

Permitted 21 years old therapeutic purposes of speech pine man: grow tall

The patient lives: Nanchang City health school sub-district

The first visit date: on March 6th, 2005; Take medicine the date: on March 8th, 2005

Predecessor's high detection: 1.63m (detection of light foot) takes medicine

The precursor type of taking medicine observation: build is normal

Diet sense of taste hobby: like sweet, the salty Shiqi of food

The motion hobby is arranged: basketball, table tennis, running

Mother patient Dai Shu: child's stature in of the same age is short partially, is that annual level is the shortest when graduating from junior middle school.It is surplus to have read health school 1 year, still is sitting in first three row in classroom, and the head of a family feels very much worried in the heart.Because stature is short partially, influence the later future of my child, such as work, join the army, marriage or the like.Participate in every year and help the sports item that increases, nutriment is also constant, but child's stature always is not good at.

Diagnostic result: growth hormone deficiency

Punishment: 3 courses of treatment of bore regenerating pill, oral one time 4.5 gram (about 25)/day, once a day.

Take and detect height after 52 days courses of treatment and increased 2 centimeters and have a surplus (detection of light foot) 1.65m

Take and detect height after two 104 days courses of treatment and increased 5 centimeters and have a surplus (detection of light foot) 1.68m

Take and detect height after three 156 days courses of treatment and increased 8 centimeters and have a surplus (detection of light foot) 1.72m

Case 3:

22 years old therapeutic purposes of Peng Ting woman: grow tall

The patient lives: No. 574, the young Xijiang River Wan Lu of colleges for training managerial personnel in Shanghai

The first visit date: on March 2nd, 2005, take medicine the date: on March 5th, 2005 rose

Predecessor's high detection: 1.55m (its grandmother, mother's stature short) takes medicine.

The precursor type of taking medicine observation: the figure is thin, and face is pale.

The hobby of the diet sense of taste: sweet food product, peppery product are secondly

The motion hobby is arranged: dislike motion, fall in love with the street and saunter

Patient's readme: height just never increases substantially after to 1.50 meters from long during 12 years old～13 years old, and height is exactly 1.55m after 18 years old, still just begins so at heart till now to worry.Once obeyed the multiple medicine that increases, the decoction of Chinese medicine was also obeyed, but height loses growth exactly.Be Shanghai hospital of Tongji University and seen yet, the Western medicine of having obeyed some months does not have improvement yet.Listen friend to say that your bore regenerating pill Chinese medicine is useful, just have the mood that tries in arms and come.

Diagnostic result: heritability, spirituality, constitutional short stature

Punishment: 3 courses of treatment of bore regenerating pill, oral one time 4.5 gram (about 25)/day, once a day

Annotate 1, take and detect afterwards 52 days courses of treatment, height has increased to 1 centimeter (detection of light foot).

Annotating phoned on August 1st, 2,2005 informs: stature is increased to: 1.61m

Case 4:

Thank to beautiful women 23 years old 08 months therapeutic purposes: grow tall, correct build.

The patient lives: No. 9 building in the brocade circle of Nankai District, Tianjin City

The first visit date: on March 1st, 2005, take medicine the date: on March 4th, 2005 rose

Predecessor's high detection: 1.59m (detection of light foot) takes medicine

The precursor type of taking medicine observation: figure's obesity, physique is horizontal

Diet sense of taste hobby: happiness food sweets

The motion hobby is arranged: do not like motion, like sleep

Mother patient Dai Shu: brother sister of our family and the children that give birth to of institute hour look soon than child's stature of the same age at the age, still one 18 years old, just always be not good at.Press present case, my Miss's height is also not very short.Just be afraid of to connect the stature of our family.Hear pure Chinese medicine bore regenerating pill, not only on health increases, work, but also can correct build deformity and inaesthetic growth momentum.I want me to obey a course of treatment in the Miss's examination earlier.

Diagnostic result: comprehensive short stature obesity

Punishment: 1 course of treatment of bore regenerating pill, oral one time 4.5 gram (about 25)/day, once a day.

Taking health after 52 days course of treatment does not have the sense of discomfort.Build reduces upright well-balanced slightly, and stature is increased to 1.60m2005 and came institute to open the place May 2 to continue to use two courses of treatment.

This head of a family sent a telegram here and claims to have reached 1.64 height on October 5th, 2005, and the figure has recovered normal fully.

Case 5:

Patient: 26 years old 06 months therapeutic purposes of He Weidong man: grow tall

The patient lives: Nanjing Military Command hospital general (No. 305, East Zhongshan Road, Nanjing)

The first visit date: on February 6th, 2005; Take medicine the date: on February 10th, 2005 rose.

Predecessor's high detection: 1.68m (measurement of light foot) takes medicine

The precursor type of taking medicine observation: build is horizontal; The abdominal part projection; The lower limb shin is short and sturdy.

The hobby of the diet sense of taste: salty food is main, and peppery food is inferior

The motion hobby is arranged: football, baseball, table tennis, basketball

Patient's readme: I just began to stop long in 22 years old, and my father and mother's stature is not high, and father has only mother 1.60m to have only 1.53m, and I wish to reach the height of order 1.75m very much.Just because the problem of height does not all find ideal work and object till now, the product of being sold on the market that increases was almost all used, and physical fitness training also did, and also having taken of nice nutrition is many.But all there is not sound over the years always.The medicine of hearing you can be all effective later in the skeleton closure, and the spy wants to have a try.

Diagnostic result: the X line detects skeleton 92% closure, belongs to hereditary comprehensive short stature

Punishment: 4 courses of treatment of bore regenerating pill, oral one time 4.5 gram (about 25)/day, once a day.

Take 104 days two courses of treatment and have a surplus 1.69 meters of light foot detections after measurement height has increased to 1 centimeter.

Take 156 days three courses of treatment and have a surplus 1.71 meters of light foot detections after measurement height has increased to 3 centimeters.

Take 208 days two courses of treatment and have a surplus 1.74 meters of light foot detections after measurement height has increased to 5 centimeters.

Claims (6)

1, a kind of healing type bore regenerating pill and preparation method can be mixed with pill and decoction as requested, belong to the medicine category.It is characterized in that:

A: calculate according to composition by weight, with ZENGGUCAO 5～9%, QIMENGHUA 7～15%, Os Draconis (calcined) 5～6%, Fructus Corni (system) 2～8%, Rhizoma Dioscoreae 1～7%, Radix Ginseng 2～5%, Cortex Moutan 1～7%, Endothelium Corneum Gigeriae Galli 5～9%, Colla Corii Asini 5～7%, Poria 3～5%, Concha Ostreae 1～5%, Carapax Trionycis 2～7%, Rhizoma Alismatis 3～5%, mixing are pulverized, are sieved;

B: oversize and fevervine (9～11%), Massa Medicata Fermentata (8～10%), Fructus Crataegi (7～11%), add water and decoct jointly, decocting liquid is condensed into thick paste,

C: thick paste, minus sieve thing, starch mixing granulation drying.

2, as said healing type bore regenerating pill of claim 1 and preparation method, it is characterized in that its oversize and fevervine, Massa Medicata Fermentata, when Fructus Crataegi decocts with water, be advisable with 1～4 time, be good with 2～3 times, with 1.5 hours the bests.

3, as claim 1 and 2 said healing type bore regenerating pill and preparation methoies, it is characterized in that it is 0.2～1.6 that its decoction liquor under reduced pressure is concentrated into relative density, be the best with 1.3.

4, healing type bore regenerating pill and preparation method is characterized in that:

A. with Semen Juglandis (7.5～10.7%) squeezing, be separated into oils and fats and oil cake;

B. with Semen Juglandis oil cake and Poria (9～12%), Radix Rehmanniae Preparata (8.5～10%), Fructus Lycii (3.5～5%), combination drying, beat powder, sieve,

C. oversize and thick paste, walnut lubricant, minus sieve thing, starch mix, and granulate.

5, as said healing type bore regenerating pill of claim 5 and preparation method, it is characterized in that Ganoderma decocts with water 2～5 hours and is advisable, 3 hours is best, adding Radix Codonopsis, the Radix Astragali, Herba Houttuyniae, oversize decoct with water 1～3 time and are advisable, 2 times is good, be advisable in each 0.5～2 hour, 1 hour is best.

6, as claim 5 and 6 said healing type bore regenerating pill and preparation methoies, it is characterized in that its decoction liquor, relative density is 1.2～1.4 when being concentrated into 20 ° under decompression or normal pressure, is the best with 1.3.