CN1876167A - Medicine for treating chronic bronchitis and its preparation method - Google Patents

Abstract

The invention discloses a medicament for treating chronic bronchitis, which is prepared from raw materials including notopterygium root, swallowwort rhizome, honey-fried licorice root, nodular branch of pine, thorny elaeagnus leaves, bitter orange, dried ginger, pubescent angelica root, red ginseng, bupleurum root, poria cocos and wasp's nest.

Description

Medicine of treatment chronic bronchitis and preparation method thereof

Technical field

The present invention relates to treat the medicine of chronic bronchitis, is the Chinese patent medicine of feedstock production with the Chinese herbal medicine particularly, the invention still further relates to the preparation method of this medicine.

Background technology

Chronic bronchitis is a common complaint among the elderly, and it is caused by the Different types of etiopathogenises long term.Chronic bronchitis mostly is lungs cold caused by deficiency, lung, spleen, it is cold to suffer from a deficiency of the kidney, immunologic hypofunction.The outstanding behaviours of chronic bronchitis is long-term cough, increases the weight of gradually, and light disease person begins morbidity whenever cold season, morning the time-out paroxysmal cough, serious symptom person coughs throughout the year, winter-spring season increases the weight of.Though the Chinese patent medicine of some treatment chronic bronchitis is also arranged, and effect is not fairly obvious.

Summary of the invention

The object of the present invention is to provide a kind of medicine for the treatment of chronic bronchitis, can the cold expelling warming the lung to relieve cough, the kidney warming helping inspiration to relieve asthma increases immunity, has antiinflammatory, reduces phlegm, the effect of relieving cough and asthma.

Another object of the present invention provides the preparation method of this treatment chronic bronchitis medicine.

Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to chronic bronchitis mechanism, with reference to the modern pharmacological research achievement, from motherland's medical treasure-house, filters out 13 Chinese crude drugs, by the theory of Chinese medical science prescription.

Medicine of the present invention is made by following component: (consumption is a weight portion)

Rhizoma Et Radix Notopterygii 10-20, process Rhizoma Cynanchi Stauntonii 10-20, Radix Glycyrrhizae Preparata 10-20, Pine Nodular Branch 10-20, Folium Elaeagni 12-24, Fructus Aurantii (parched) 4-20, Rhizoma Zingiberis 10-20, Radix Angelicae Pubescentis 4-20, Radix Ginseng Rubra 4-20, fry Cortex Alstoniae scholaris 10-20, Radix Bupleuri (processed with vinegar) 4-20, Poria 4-14, fry Nidus Vespae 12-24.

Formula optimization weight (part) ratio range of preparation medicine of the present invention is:

Rhizoma Et Radix Notopterygii 12-18, process Rhizoma Cynanchi Stauntonii 12-18, Radix Glycyrrhizae Preparata 12-18, Pine Nodular Branch 12-18, Folium Elaeagni 14-22, Fructus Aurantii (parched) 8-16, Rhizoma Zingiberis 12-18, Radix Angelicae Pubescentis 8-16, Radix Ginseng Rubra 8-16, fry Cortex Alstoniae scholaris 12-18, Radix Bupleuri (processed with vinegar) 8-16, Poria 6-12, fry Nidus Vespae 14-22.

Prescription optimum weight (part) proportioning of preparation medicine of the present invention is:

Rhizoma Et Radix Notopterygii 15, process Rhizoma Cynanchi Stauntonii 15, Radix Glycyrrhizae Preparata 15, Pine Nodular Branch 15, Folium Elaeagni 18, Fructus Aurantii (parched) 12, Rhizoma Zingiberis 15, Radix Angelicae Pubescentis 12, Radix Ginseng Rubra 12, fry Cortex Alstoniae scholaris 15, Radix Bupleuri (processed with vinegar) 12, Poria 9, fry Nidus Vespae 18.

Above-mentioned each component is made medicine production method of the present invention is:

1, earlier the Radix Bupleuri sheet is mixed thoroughly with vinegar, put in the pot and fry to the vinegar exhaustion, take out to dry and promptly make Radix Bupleuri (processed with vinegar), wherein consumption: Radix Bupleuri 10, vinegar 1.2 (weight portion) with slow fire;

2, with the Rhizoma Cynanchi Stauntonii sheet with cooked Mel poach, slow fire is fried to honeydew and is all blotted by Rhizoma Cynanchi Stauntonii, is isabelline, is advisable with tack-free, takes out to cool promptly to make and processs Rhizoma Cynanchi Stauntonii, consumption: Rhizoma Cynanchi Stauntonii 10, cooked Mel 2.5 (weight portion);

3, get wheat bran and be spread in the heat pot, when treating that yellow skin is smoldered, add the Fructus Aurantii sheet, fry, remove wheat bran, promptly get Fructus Aurantii (parched), consumption: Fructus Aurantii sheet 10, wheat bran 0.1 (weight portion) to faint yellow taking-up;

4, with Radix Glycyrrhizae tabellae with cooked Mel poach, put in the pot and fry to becoming buff with slow fire, be advisable with tack-free, taking-up cools, and promptly gets Radix Glycyrrhizae Preparata, consumption: Radix Glycyrrhizae tabellae 10, cooked Mel 2.5 (weight portion);

5, get Nidus Vespae and clean steaming thoroughly, be cut into small pieces and dry, fry, promptly get and fry Nidus Vespae to little yellow;

6, the air-dry back of 13 medicines of described prescription pulverize separately is become 120 purpose fine powders, all the powder component is by described formula proportion mixing, the powder medicine of the chronic bronchitis that can obtain medical treatment.

Powder of the present invention also can be processed into tablet or granule or watered pill preparation.

The function of medicine of the present invention with cure mainly: the cold expelling warming the lung to relieve cough, the kidney warming helping inspiration to relieve asthma increases immunity.Cure mainly new, of a specified duration cough illness such as cough with asthma and asthma chronic bronchitis, emphysema, pulmonary heart disease.

The side of medicine of the present invention separates: this powder is got Radix Ginseng and is relieved internal heat with Rhizoma Cynanchi Stauntonii for Radix Peucedani, goes Radix Platycodonis to add Rhizoma Zingiberis and removes Rhizoma Chuanxiong, adds Cortex Alstoniae scholaris, Folium Elaeagni, Pine Nodular Branch, Nidus Vespae again and forms.Cold in nature because of Radix Peucedani, run counter to cold the coughing of the deficiency of the lung and get with Rhizoma Cynanchi Stauntonii, Radix Platycodonis is cold in nature to some extent should not be so replace Rhizoma Zingiberis to asthenia-cold of lung-QI, the original author ends headache with Rhizoma Chuanxiong for dispeling the wind and establishes, and the contrary gas of cough with asthma is feared improperly to some extent to die it.Should loose and breathe heavily gas with Rhizoma Et Radix Notopterygii, Folium Elaeagni warming lung for dispelling cold, helping inspiration to relieve asthma cough-relieving is monarch; With Radix Angelicae Pubescentis, Radix Bupleuri, Fructus Aurantii, Nidus Vespae, Radix Ginseng, Pine Nodular Branch, Cortex Alstoniae scholaris, Poria principal drug assistance releasing kidney volt wind, the evil respectful lung that looses, the kidney warming improving inspiration by invigorating kidney-QI, relieving cough and asthma, enhancing resistance against diseases is minister; Radix Glycyrrhizae, Rhizoma Zingiberis are assistant; Rhizoma Cynanchi Stauntonii is for making.But it is the multiple gas of Radix Glycyrrhizae Rhizoma Zingiberis soup warming the lung that Radix Glycyrrhizae and Rhizoma Zingiberis match, and imitates good to cough with asthma of asthenia cold type.Whole Fang Yi be warming the lung with cough-relieving, improving inspiration by invigorating kidney-QI to be relievining asthma, touching more when disease-resistant imperial heresy with exhausted its disease.

Rhizoma Et Radix Notopterygii in the side: hot, bitter, warm.The exterior cold of loosing is cold to remove in the lung, and Folium Elaeagni: acid is flat.Control cough and asthma, hemoptysis ...." Huatuo's Zhongzang classic ": " controlling gas on the cough with asthma "." detailed outline ": " the ruined leaf of Pu (name Folium Elaeagni) is controlled cough with asthma side, goes out " Huatuo's Zhongzang classic " ", very the person is also imitated.Cloud has to suffer to be breathed heavily 30 years, and pausing of clothes healed.(" Chinese medicine voluminous dictionary " 1552 pages) Radix Angelicae Pubescentis: suffering, hardship, temperature.Expelling pathogenic wind from the body surface." property of medicine opinion ": " all rheumatism is cold in main, the dyspnea gas of running quickly ...." Radix Bupleuri: " Japan hanako materia medica ": " mend five kinds of strain and seven kinds of impairment ... physical strength profiting, expectorant antitussive, profit cardiopulmonary ...." (" Chinese medicine voluminous dictionary " 1835 pages) Fructus Aurantii: dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant and stagnate, the feeling of stuffiness in chest, the side of body expand ...." Kaibao Bencao ": " the main air paralysis of itching ... consumptive disease cough ...." Nidus Vespae: " book on Chinese herbal medicine is stated ": " controlling long-pending expectorant chronic cough ".Zhu Liang spring old docter of TCM experience: " control chronic tracheitis, chronic cough endlessly, and is not only efficient but also quick-acting, really is a good medicine of cheap and good-quality relieving cough and resolving phlegm, the warming the lung kidney nearly also arranged, receive against the merit of gas." (" Zhu Liang spring medication experience collection " 102 pages).Radix Ginseng: strongly invigorating primordial QI, promote the production of body fluid admittedly take off, calm the nerves.Controlling consumptive disease hinders deficient ... empty cough with asthma is short ...." book on Chinese herbal medicine covers mirror ": " relieving asthma and cough; Promoting blood circulation ... ".The modern study proof can improve people's the general mentality and the function of muscle power.(" Chinese medicine voluminous dictionary " 31 pages) Pine Nodular Branch: Zhu Liang spring old docter of TCM experience: " Gu health blood is controlled the numbness sleeplessness of coughing, find the length that this product has tonify deficiency to consolidate, decrease severe and lingering illness, the merit of recovery is arranged greatly " to winning as all.And think and can improve immunologic function, to the bromhidrosis weakness, be easy to flu, repeatedly the infected, get Pine Nodular Branch 30 grams every day, 7 pieces of decoctions of Fructus Jujubae, logotype 1 month improves the merit that Gu Wei drives heresy again, the invasion and attack of energy preventing cold, what praise is " Chinese medicine gamma globulin ", and that tests is clinical, and letter is not falsely accused yet." to chronic bronchitis cough, do not heal for a long time, sputum is thin, and the not red person of body of the tongue adds with this product 20-30 and restrains in distinguishing the side of controlling, and the merit of enhancing relieve coughing cough-relieving is arranged ".(" Zhu Liang spring medication experience collection " 37 pages) Cortex Alstoniae scholaris: cure cold, pneumonia, pertussis ....So the title of " setting Herba Hedyotis scandentis greatly " is arranged.Once report treatment chronic bronchitis is got 2 of Cortex Alstoniae scholaris extractum sheets (every suitable crude drug in whole 1.7 grams) at every turn, 1 of bent lotus Saponin sheet (every content 60 milligrams) is oral, and every day 3 times, 10 is a course of treatment, through treating 210 examples, clinical cure 56 examples (26.6%) as a result, produce effects 54 examples (25.9%), 94 examples that take a turn for the better (44.7%), invalid 6 examples (2.8%), facts have proved to have antiinflammatory, reduce phlegm, antitussive action, and certain antiasthmatic effect is arranged.(" Chinese medicine voluminous dictionary " 2214 pages) Poria: eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.Control dysuria, edema distension, phlegm retention cough with dyspnea ....Be the sick habitual medicine of phlegm retention.Radix Glycyrrhizae Preparata: and middle emergency, lung moistening detoxifcation ... control the consumptive lung disease cough.The modern pharmacology proof has good antitussive effect.Can be used for tracheitis, pharyngolaryngitis, sound loud, high-pitched sound, asthma.10 milliliters of report treatment bronchial asthma usefulness Radix Glycyrrhizae powder 5 grams or Radix Glycyrrhizae fluid extracts are arranged, every day 3 times.3 routine chronic and refractory bronchial asthmas are controlled in examination, obtain remarkable result.(" Chinese medicine voluminous dictionary " 569,571 pages) Rhizoma Zingiberis: suffering, heat.Warming spleen and stomach for dispelling cold is controlled cold fluid-retention and is breathed with cough.Rhizoma Cynanchi Stauntonii: eliminate the phlegm, sending down the abnormal ascending QI, cough-relieving.Tang Materia Medica: " Your Majesty's gas is breathed wild in larynx." " Bencao Jingshu ": " Rhizoma Cynanchi Stauntonii, the key medicine of lung man ".

For showing the therapeutic effect of medicine of the present invention to chronic bronchitis, the present invention is through the clinical observation of 120 routine systems, and clinical drug operating position of the present invention is as follows:

Treatment and matched group: medicine of the present invention and identical 40 examples of respectively treating of " tetrahydro-isoquinolin sheet " disease are got by treatment matched group system.For objective and fair, to control from dialectical executing, 40 examples of all tetrahydro-isoquinolin sheets treatment meet exogenous cold interior-heat or the hot and suffocating card of lungs entirely.

Medicine of the present invention is with early, middle and late food every day back half an hour of each usefulness warm boiled water 9 gram.Obey 15 days one courses of treatment, serve on 3 summaries courses of treatment, comparing result.

Tetrahydro-isoquinolin sheet: (produce by the LiaoYuan YaDong Medicine Co., Ltd., Jilin Province.The accurate word Z22025871 of traditional Chinese medicines.This medicine group wants composition to be made up of Herba Ephedrae, Fel Sus domestica, Semen Armeniacae Amarum frost, Radix Platycodonis, Radix Glycyrrhizae.This medicine has Xin Liang to lead off, and removing heat from the lung and dissipating phlegm is relievingd asthma, the function of cough-relieving.Be applicable to cough illness.Usage and consumption: oral, a 3-4 sheet, 3 times on the one.) points for attention are in strict accordance with explanation.Serve on for 3 courses of treatment equally and make curative effect relatively.Why comparing with tetrahydro-isoquinolin, is because of the better curative effect of part is arranged in the type patient group.Table 1 is medication therapy groups 80 routine therapeutic outcome statistical tables of the present invention.

Table 1

Disease name	Total routine number	Cure number	Produce effects	Effectively	Cure rate, total effective rate	Invalid
							The simple type chronic bronchitis	33	24	4	3	61％ 91％	2
The type of panting chronic bronchitis	26	19	3	2		2
							Chronic bronchitis merges slight emphysema	10	6	4
Chronic bronchitis merges severe emphysema	6		4	1		1
							Chronic bronchitis merges pulmonary heart disease	5		2	1		2
Add up to	80	49	17	7		7

Table 2 medicine of the present invention, each 40 routine Comparison of therapeutic of tetrahydro-isoquinolin sheet.

Table 2

The medicine name	Disease name	Total routine number	Cure number	Produce effects	Effectively	Cure rate, total effective rate	Invalid
								Medicine of the present invention	The simple type chronic bronchitis	15	13	1	1	63％ 93％
The type of panting chronic bronchitis	3	2	1
							Chronic bronchitis merges slight emphysema		15	10	1	2
Chronic bronchitis merges severe emphysema	6		3	2		2
							Chronic bronchitis merges pulmonary heart disease		1			1		1
	Add up to	40	25	6	6										3
							The medicine name	Disease name	Total routine number	Cure number	Produce effects	Effectively	Cure rate, total effective rate	Invalid
The tetrahydro-isoquinolin sheet	The simple type chronic bronchitis	15	5		3	28％ 53％									5
							The type of panting chronic bronchitis	3	1	2	1		1
	Chronic bronchitis merges slight emphysema	15	5		1									9
							Chronic bronchitis merges severe emphysema	6			3		3
	Chronic bronchitis merges pulmonary heart disease	1												1
								Add up to	40	11	2	8			19

Therapeutic outcome:

Treatment group and treatment matched group are all according to national chronic bronchitis clinical speciality meeting revised standard in 1979.Recovery from illness: after 3 drug withdrawals course of treatment of taking medicine, observe the half a year of other relevant medicines of adhib not, clinical symptom disappearance, auscultation of lung does not have rale, and X ray examination lung marking is normal, and erythrocyte sedimentation rate and hemogram are normal.Produce effects: symptom takes a turn for the better, and flu obtains prevention, and X ray examination lung marking is normal, and erythrocyte sedimentation rate and hemogram are normal.Take a turn for the better: sx, lung marking reduces, and erythrocyte sedimentation rate and hemogram are normal.Invalid: take medicine 3 courses of treatment, subjective symptoms does not subtract, and still often catches a cold, and various inspections do not have improvement.Medication therapy groups to 80 example as a result of the present invention is summed up cure rate 61% 3 courses of treatment, and total effective rate (healing, produce effects, effective sum) is 91%, and 40 routine cure rates of medicine of the present invention and the contrast of tetrahydro-isoquinolin sheet are 63%, and total effective rate is 93%.120 routine total cure rates are 62%, and total effective rate is 92%.It is 28% that 40 examples of tetrahydro-isoquinolin sheet treatment are cured, and total effective rate is 53%, and is bigger with this comparing difference.

The bronchitis of modern medicine name, with cough, expectorant, to breathe heavily be main clinical manifestation, and bronchial asthma one disease is arranged again, can belong to traditional Chinese medical science cough, asthma, the category of heavy breathing disease and pulmonary distension disease.Sick by always not going out asthenia-cold of lung-QI, weakened defensive QI, lung, spleen, kidney three deficiency of five ZANG-organs are cold.Say as " interior warp ": " impairment of the lung by exogenous cold and cold drinking ".Because malpractice or mistake are controlled to the lung being invaded by pathogenetic wind is cold stays for a long time, cough is not understood, and coughs the deficiency of the lung of a specified duration at the beginning of being subjected to disease, and to deficiency of both the lung and kidney, impairment of purifying and descending function of the lung, kidney lose to take the photograph and receive and cough with asthma is touching.Promptly as " Medicine Comprehended " said: " allly control cough, be valued for from the beginning of doing in the proper way and do good, the heresy of not loosing is not then gone, and crosses to loose that then lung qi is necessary, all causes touching difficulty and heals "." Standards of Diagnosis and Treatment " were once said: " deficiency of the lung is shortness of breath and dyspnea then "." doctor is used to, and breathes heavily " also said: " very first loss, lung is for running quickly on the kidney ... be that gas is not returned former yet ".

Cough with asthma is touching disease since the dawn of human civilization, especially cough, surplus before 25 years, thought do not have to cut a good recipe of coughing.After (" the secret proved recipe of well-known doctor at all times " Lu Zhenping chief editor) draw Chen Fuzheng and speak: " Renshen Baidu San is for coughing the family status one god side, the throughout the world rare person of knowing." so all chance wind-cold tightening the lungs and deficiency and coldness cough disease, the side is air-drop never, and is vertical through the multi-treatment person, executes three or five doses invariably and promptly accuses the merit of fullying recover from an illness.From then on further investigation is constantly improved and is made into medicine of the present invention.Medicine of the present invention is to build on chronic bronchitis mostly to be the lungs cold caused by deficiency, lung, spleen, suffer from a deficiency of the kidney cold, the pathogenesis of immunologic hypofunction, sick body understanding thought, and chronic cough must cause and breathe heavily, and breathes heavily not formulated from the understanding viewpoint of coughing.Have first condition of disease and cut and cough, prolonged illness can be relievingd asthma, and exhausted root increases immunity, the drug effect characteristics that cough with asthma is not touching.Be widely used in chronic bronchitis, stupid cough with asthma of a specified duration such as chronic bronchitis and emphysema, pulmonary heart disease.Clinical cure rate is 62%, and total effective rate is 92%, compares with tetrahydro-isoquinolin that there were significant differences.

The specific embodiment

Take by weighing raw material (kilogram) by following proportioning

Rhizoma Et Radix Notopterygii 15, process Rhizoma Cynanchi Stauntonii 15, Radix Glycyrrhizae Preparata 15, Pine Nodular Branch 15, Folium Elaeagni 18, Fructus Aurantii (parched) 12, Rhizoma Zingiberis 15, Radix Angelicae Pubescentis 12, Radix Ginseng Rubra 12, fry Cortex Alstoniae scholaris 15, Radix Bupleuri (processed with vinegar) 12, Poria 9, fry Nidus Vespae 18.

Production method is as follows:

Medicine of the present invention is made up of above-listed 13 medicines, and every essential first quality of medicine is also concocted with method.Rhizoma Et Radix Notopterygii: it is sturdy to get bar, has protuberance tortuous ring grain, section matter tight, and spot of oil cavity is many, the person of giving off a strong fragrance silkworm Qiang (having another name called screw Qiang).Folium Elaeagni: get big person, chopping is dried and is the end.Radix Angelicae Pubescentis: sturdy entirely, the fragrant person of gas.Radix Bupleuri (processed with vinegar): get root bar slightly length, thin, the few person's Radix Bupleuri sheet of supporting root of skin, mix thoroughly with vinegar, put and use exhaustion of slow fire parch vinegar and little doing in the pot, taking-up is dried.(100 kilograms of every Radix Bupleuri, with vinegar 12 kilograms) processs Rhizoma Cynanchi Stauntonii: get that rhizome is thick, fibrous root long, no earth and impurity person cut into slices.Get the Rhizoma Cynanchi Stauntonii sheet and add water with cooked Mel and mix thoroughly in right amount, slow fire is fried to honeydew and is all blotted, and is the isabelline tack-free degree that is, taking-up cools.(100 kilograms of every Rhizoma Cynanchi Stauntoniis are with 25 kilograms of cooked Mel), Fructus Aurantii (parched): get wheat bran and be spread in the heat pot, when treating that yellow skin is smoldered, add the Fructus Aurantii sheet, fry, remove wheat bran to faint yellow taking-up.(100 kilograms of every Fructus Aurantii sheets are with 1 kilogram in wheat bran), Radix Ginseng Rubra: get height, Zhi Dazhe.Poria: get that body weight is solid, section is white, fine and smooth, the power that sticks to one's teeth is strong, and is greasy and the sliding sense person of powder arranged.Radix Glycyrrhizae Preparata: the extracting liquorice sheet adds cooked Mel, and a little is mixed thoroughly to decontrol water, and is stewing slightly, puts in the pot and fries to becoming buff with slow fire, and tack-free is degree, and taking-up cools.(25 kilograms of the cooked Mel of 100 kilograms of usefulness of every Radix Glycyrrhizae tabellae) Rhizoma Zingiberis: it is solid to get matter, crust lark, interior canescence, section mealiness foot, few muscle arteries and veins person good merchantable brand.Fry Cortex Alstoniae scholaris: the Cortex Alstoniae scholaris after getting leaf or removing Lao Pi is cut into the filament strip slow fire that dries in the shade to be fried to the little burnt color of fulminant leucorrhagia with yellowish discharge and is degree.Fry Nidus Vespae: get that single, neat, canescence, tube length, hole are little, body gently, slightly flexible, interior no larva and impurity person.Clean and steam thoroughly, be cut into small pieces and dry, slightly fry to little yellow.Pine Nodular Branch: good with individual big, brownish red, oiliness foot person.

Last 13 medicine systems finish, and drying or drying the back pulverize separately is 120 purpose smalls, and mixing promptly makes powder of the present invention.Medicine of the present invention also can be made into tablet, granule or the watered pill.

Claims (5)

1, a kind of medicine for the treatment of chronic bronchitis is characterized in that the medicament of being made by following materials of weight proportions: Rhizoma Et Radix Notopterygii 10-20, process Rhizoma Cynanchi Stauntonii 10-20, Radix Glycyrrhizae Preparata 10-20, Pine Nodular Branch 10-20, Folium Elaeagni 12-24, Fructus Aurantii (parched) 4-20, Rhizoma Zingiberis 10-20, Radix Angelicae Pubescentis 4-20, Radix Ginseng Rubra 4-20, fry Cortex Alstoniae scholaris 10-20, Radix Bupleuri (processed with vinegar) 4-20, Poria 4-14, fry Nidus Vespae 12-24.

2, the medicine of treatment chronic bronchitis according to claim 1 is characterized in that: wherein the weight proportion of each raw material is: Rhizoma Et Radix Notopterygii 12-18, process Rhizoma Cynanchi Stauntonii 12-18, Radix Glycyrrhizae Preparata 12-18, Pine Nodular Branch 12-18, Folium Elaeagni 14-22, Fructus Aurantii (parched) 8-16, Rhizoma Zingiberis 12-18, Radix Angelicae Pubescentis 8-16, Radix Ginseng Rubra 8-16, fry Cortex Alstoniae scholaris 12-18, Radix Bupleuri (processed with vinegar) 8-16, Poria 6-12, fry Nidus Vespae 14-22.

3, the medicine of treatment chronic bronchitis according to claim 1 is characterized in that: wherein the weight proportion of each raw material is: Rhizoma Et Radix Notopterygii 15, process Rhizoma Cynanchi Stauntonii 15, Radix Glycyrrhizae Preparata 15, Pine Nodular Branch 15, Folium Elaeagni 18, Fructus Aurantii (parched) 12, Rhizoma Zingiberis 15, Radix Angelicae Pubescentis 12, Radix Ginseng Rubra 12, fry Cortex Alstoniae scholaris 15, Radix Bupleuri (processed with vinegar) 12, Poria 9, fry Nidus Vespae 18.

4, according to the medicine of claim 1 or 2 or 3 described treatment chronic bronchitis, it is characterized in that: said medicine is powder or tablet or granule or watered pill preparation.

5, the preparation method of the medicine of treatment chronic bronchitis according to claim 4, it is characterized in that: (1), elder generation mix the Radix Bupleuri sheet thoroughly with vinegar, put in the pot and fry to the vinegar exhaustion, take out to dry and promptly make Radix Bupleuri (processed with vinegar), wherein the consumption weight proportion: Radix Bupleuri 10, vinegar 1.2 with slow fire; (2), with the Rhizoma Cynanchi Stauntonii sheet with cooked Mel poach, slow fire is fried to honeydew and is all blotted by Rhizoma Cynanchi Stauntonii, is isabelline, is advisable with tack-free, takes out to cool promptly to make and processs Rhizoma Cynanchi Stauntonii, wherein the consumption weight proportion: Rhizoma Cynanchi Stauntonii 10, cooked Mel 2.5 (; (3), get wheat bran and be spread in the heat pot, when treating that yellow skin is smoldered, add the Fructus Aurantii sheet, fry to faint yellow taking-up, remove wheat bran, promptly get Fructus Aurantii (parched), wherein the consumption weight proportion: Fructus Aurantii sheet 10, wheat bran 0.1; (4), with Radix Glycyrrhizae tabellae with cooked Mel poach, put in the pot and fry to becoming buff with slow fire, be advisable with tack-free, taking-up cools, and promptly gets Radix Glycyrrhizae Preparata, wherein the consumption weight proportion: Radix Glycyrrhizae tabellae 10, cooked Mel 2.5; (5), get Nidus Vespae and clean to steam thoroughly, be cut into small pieces and dry, fry to little yellow, promptly get and fry Nidus Vespae; (6), the air-dry back of 13 medicines of described prescription pulverize separately is become 120 purpose fine powders, all the powder components are by described formula proportion mixing, the powder medicine of the chronic bronchitis that can obtain medical treatment.