CN1867822B - 通过测量荧光寿命在生物测试体系中直接观察分子修饰 - Google Patents

通过测量荧光寿命在生物测试体系中直接观察分子修饰 Download PDF

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Publication number
CN1867822B
CN1867822B CN2004800306399A CN200480030639A CN1867822B CN 1867822 B CN1867822 B CN 1867822B CN 2004800306399 A CN2004800306399 A CN 2004800306399A CN 200480030639 A CN200480030639 A CN 200480030639A CN 1867822 B CN1867822 B CN 1867822B
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China
Prior art keywords
molecule
reaction
fluorescence lifetime
flt
fluorescence
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Expired - Fee Related
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CN2004800306399A
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English (en)
Chinese (zh)
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CN1867822A (zh
Inventor
F·-J·迈尔-阿尔默斯
G·维尔茨
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Bayer Pharma AG
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Bayer Schering Pharma AG
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Priority claimed from DE200410022107 external-priority patent/DE102004022107A1/de
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Priority claimed from PCT/EP2004/011100 external-priority patent/WO2005043137A1/de
Publication of CN1867822A publication Critical patent/CN1867822A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence

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  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN2004800306399A 2003-10-18 2004-10-05 通过测量荧光寿命在生物测试体系中直接观察分子修饰 Expired - Fee Related CN1867822B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10348949.5 2003-10-18
DE2003148949 DE10348949A1 (de) 2003-10-18 2003-10-18 Direkte Beobachtung molekularer Veränderungen ind biologischen Testsystemen mittels Messungen der Fluoreszenz-Lebensdauer
DE102004022107.3 2004-05-05
DE200410022107 DE102004022107A1 (de) 2004-05-05 2004-05-05 Direkte Beobachtung molekularer Veränderungen in biologischen Testsystemen mittels Messungen der Fluoreszenz-Lebensdauer
PCT/EP2004/011100 WO2005043137A1 (de) 2003-10-18 2004-10-05 Direkte beobachtung molekularer veränderungen in biologischen testsystemen mittels messungen der fluoreszenz-lebensdauer

Publications (2)

Publication Number Publication Date
CN1867822A CN1867822A (zh) 2006-11-22
CN1867822B true CN1867822B (zh) 2011-03-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2004800306399A Expired - Fee Related CN1867822B (zh) 2003-10-18 2004-10-05 通过测量荧光寿命在生物测试体系中直接观察分子修饰

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CN (1) CN1867822B (de)
DE (1) DE10348949A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102585730B1 (ko) 2014-08-08 2023-10-10 퀀텀-에스아이 인코포레이티드 수신된 광자들의 시간 비닝을 위한 집적 디바이스
CN104293929A (zh) * 2014-09-28 2015-01-21 南京诺唯赞生物科技有限公司 一种定量t4多聚核苷酸激酶活性测定方法
WO2017143129A1 (en) 2016-02-17 2017-08-24 Tesseract Health, Inc. Sensor and device for lifetime imaging and detection applications
MX2019007530A (es) 2016-12-22 2019-08-16 Quantum Si Inc Fotodetector integrado con agrupamiento de pixeles directo.
CA3108295A1 (en) 2018-06-22 2019-12-26 Quantum-Si Incorporated Integrated photodetector with charge storage bin of varied detection time

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Publication number Publication date
CN1867822A (zh) 2006-11-22
DE10348949A1 (de) 2005-05-19

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