CN1859896A - Dental bleaching - Google Patents
Dental bleaching Download PDFInfo
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- CN1859896A CN1859896A CN 200480023167 CN200480023167A CN1859896A CN 1859896 A CN1859896 A CN 1859896A CN 200480023167 CN200480023167 CN 200480023167 CN 200480023167 A CN200480023167 A CN 200480023167A CN 1859896 A CN1859896 A CN 1859896A
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Abstract
The present application concerns a composition for whitening one or more tee th comprising a whitening agent and petrolatum, espacially white petrolatum. In one embodiment of the invention, the composition comprises a peroxide, a solvent, a polyoxyalkylene, a petrolatum and a polyvinyl pyrrolidone.
Description
The cross reference of related application
The application requires the priority of U.S. Provisional Patent Application serial number of submitting to based on August 13rd, 2,003 60/494567 and the U.S. Provisional Patent Application serial number of submitting on April 5th, 2,004 60/559032, and therefore all the elements of these documents are used as list of references together in this manual.
Technical field
The present invention relates to the method for dental bleaching compositions and use said composition.
Background technology
Adamantine spot may be that the chemical damage by painted, aging or tooth causes.The reason of more common generation tooth stain has medicine, coffee, tea or medicated cigarette.The people who drinks laughable soft drink in a large number also can occur similarly painted.Except painted, also have other to influence the factor of people's color of teeth.Heredity may be played a role.Some man day odontiasis enamel is just white than others.Disease also can be a factor, and some medicines can cause the tooth stain.
Though pure white tooth is considered to market demand always, the use of brightening or bleaching gel still has problems.Dental hyperesthesia often is a undesirable side effect, because all bleaching gels all can cause dental hyperesthesia in various degree.Tooth is exposed to bleaching for a long time and also has many other negative effects in the gel, and for example the calcium of adamantine layer is lower than at 5.5 o'clock and follows Demineralisation and dissolve, bleach gel and may cause the damage of pulp tissue and the digestion of described bleaching gel/saliva solution intact enamel and Dentinal infiltration at pH.But the U.S. Patent number 6458340 of authorizing Ibsen etc. is considered to an exception that merits attention for undesirable dental hyperesthesia side effect.
Remain a kind of method of the painted or spot at tooth by the liquid lime chloride whitening teeth.These products contain peroxide, and it in fact is the bleaching enamel.These products normally lean on urea peroxide as bleach, and can obtain several different concentration (10%, 16%, 22%).The brightening agent that contains peroxide is contained in the gel usually, and is placed in the tooth protection cover.The using method various kinds.Use two secondary actions some in two weeks of products interior every days, and some needs use to spend the night at 1-2 in week.
At present, teeth whitening or bleaching generally include by the dentist and use whitening gel (" application on patient chair limit (chairside application) ") in his/her clinic, use whitening gel (for example " boil interlock (boil andbite) " groove) with customized, preformed or alveolus that user is shaped or tooth protection cover before using gel, perhaps with containing brightening agent, containing other dentifrice that helps the reagent of health sometimes and brush teeth.These practical applications rely on expensive professional equipment, tooth protection cover or alveolar use or contain the use repeatedly of the toothpaste of brightening agent.
Described bleaching composition by water-soluble glue or polymer as substrate, usually and alveolus, tooth protection overlap or holder (stint) is used for carrying dental bleaching agent together.For example, comprise the percarbonate and the perborate of peroxide, alkali metal and alkaline-earth metal or contain the complex of hydrogen peroxide in the bleach.In addition, also the peroxide salt of conventional base metal or alkaline-earth metal can be used for whitening teeth.U.S. Patent number 5922307 and 6331292 has been recorded and narrated the multiviscosisty mixture that will contain hydrogen peroxide and has been used as brightening agent.The pH scope of wherein said product is 6.0～10.0.
Denomination of invention all is that the U.S. Patent number 5922307,6312670 and 6514543 of " dental bleaching compositions (Tooth bleaching compositions) " relates to the chemical compound that contains hydrogen peroxide, and described chemical compound is maintained in the presence of calcium chelating agent in the dental bleaching process in 6.0～10.0 the roughly stable p H scope.
In addition, the thin polymer ribbon that floods through bleaching compounds must cover on the tooth when bleaching and keep in position.For example, the U.S. Patent number 5891453 that is entitled as " transmission system (Delivery system for a tooth whitener using a strip ofmaterial having low flexural stiffness) that is used to use the brightener for tooth of the material band with low bending stiffness " relates to and being used for the system of teeth whitening material Transfer to many adjacent teeth, and this transmission system comprises bendable material band with enough flexibilities and the teeth whitening material that is used for forming curved shape on many adjacent teeth.The easy deformable ground of this material band adapts to the space between dental surface and tooth when placing transmission system.The teeth whitening material is coated on this material band, makes when being placed on transmission system on the dental surface, this material touches dental surface and active substance is discharged on this surface.This material is also realized the bonding of this material band and dental surface, thereby transmission system is kept being enough to make in position the time of active substance onset on this surface.The method of this transmission comprises in advance the coating material band or allows the wearer that medicament is coated on the material band, and then transmission system sticked on dental surface.
The U.S. Patent number 5894017 that is entitled as " transmission system (Delivery system for an oral care substance using a strip of materialhaving low flexural stiffness) that is used to use the oral care substance of the material band with low bending stiffness " relates to a kind of transmission system that is used for oral care substance, this system comprises a kind of band, and the bending stiffness that records described stripping according to ASTM method of testing D2923-95 on Handle-O-Meter is lower than about 50 gram per centimeters.When the easy deformable ground of this material band when placing transmission system adapts to tooth and adjacent soft tissue thereof.This transmission system also comprises oral care substance is coated on this material band, and when making on transmission system being placed on dental surface and adjacent soft tissue thereof, this material touches this surface and active substance is discharged on this surface.This material is also realized the bonding of this material band and dental surface, thereby transmission system is kept being enough to make in position the time of active substance onset on this surface.The method of transmitting comprises coating material band in advance, allows the wearer that medicament is coated on the material band, perhaps allows the wearer before the materials used band medicament directly is being coated on this surface.
The U.S. Patent number 6096328 that is entitled as " transmission system (Delivery system for an oral care substance using a strip of materialhaving low flexural stiffness) that is used to use the oral care substance of the material band with low bending stiffness " relates to a kind of system of oral care substance to oral surfaces that be used to transmit, and described transmission system comprises the bendable material band with enough flexibilities of the profile that is used to adapt to oral surfaces.When the easy deformable ground of this material band when placing transmission system adapts to oral surfaces.This oral care substance is painted on this material band, makes that active substance touches this surface when being placed on transmission system on the oral surfaces.This oral care substance is also realized the bonding of this material band and oral surfaces, thereby transmission system is kept being enough to make in position the time of active substance onset on this surface.Transmit this oral care substance and comprise coating material band in advance to the method for oral surfaces, allow the wearer that oral care substance is coated on the material band, perhaps allow the wearer that oral care substance directly is coated on and exist side by side on this surface soon that the material band sticks on the oral care substance of coating.
Summary of the invention
The present invention relates generally to the dental bleaching compositions and uses the method for said composition.Said composition comprises brightening agent and is used to keep the substrate of brightening agent, is about to brightening agent and is discharged into dental surface with whitening teeth.The example of this substrate has vaseline, for example the solid white petrolatum.
On the one hand, the invention is characterized in a kind of compositions that is used to brighten or many teeth.Described compositions comprises brightening agent and vaseline, for example white petrolatum.
On the other hand, the invention is characterized in a kind of compositions that is used to brighten or many teeth, described compositions comprises peroxide, solvent, polyoxyalkylene, vaseline and polyvinylpyrrolidone.
On the other hand, the invention is characterized in a kind of method that brightens or many teeth.Described method is included in the bleaching composition that applies the treatment effective dose on or many teeth.Described bleaching composition comprises brightening agent and vaseline.Described bleaching composition and one or many teeth keep in touch, thereby described bleaching composition can brighten one or many teeth.In concrete enforcement, carry out the described process that applies by being coated with described compositions.
Other embodiment and/or aspect can comprise following each or their combination.Described vaseline accounts for about 10～90 weight % in described compositions.Described vaseline at room temperature is a solid.Described vaseline is made up of white petrolatum.Described brightening agent is a peroxide.Described peroxide accounts for about 35～70 weight % in described compositions.Described compositions can also comprise viscosifier, for example polyvinylpyrrolidone, starch, polyoxyalkylene or their mixture.Described viscosifier account for about 5～30 weight % in described compositions.Described compositions can also comprise solvent, for example water, glycerol, Polyethylene Glycol or their mixture.
In one embodiment, the invention provides the method for one of a kind of processing or many teeth.Described method comprises the steps: the bleaching composition of treatment effective dose is coated on one or many teeth by alveolus, tooth protection cover, holder or bar-shaped applicator, perhaps allow bleaching composition and one or many teeth keep in touch, thereby described bleaching composition can whitening teeth.
In another embodiment, the invention provides the test kit of one of a kind of processing or many teeth.In such embodiment, described test kit comprises: have the cap portion of threaded structure and from the bar-shaped applicator of the extended applicator of cap portion part; The helicitic texture that Lightening compositions container with the inner space that is used for depositing Lightening compositions, described container have and the helicitic texture of bar-shaped applicator cap portion coincide; And the Lightening compositions in the described Lightening compositions container.
Another embodiment of the invention relates to the compositions of whitening teeth.Described compositions can comprise one or more brightening agents (3～30% hydrogen peroxide and 9～45% urea peroxides) that account for about 3～about 30 weight %; Account for one or more viscosifier (3～50%PVP and 10～9% vaselines) of about 3～about 50 weight %; And account for about 1～about 20 weight %, for example one or more solubilizing agents of about 1～about 5 weight %.
Another embodiment of the invention relates to the compositions with following composition, and % represents with weight:
| Composition is described | Weight % |
| Hydrogen peroxide | 5.00 |
| Water | 5.00 |
| Polyoxyalkylene | 5.00 |
| White petrolatum | 74.250 |
| Polyvinylpyrrolidone | 10.000 |
| Flavoring agent | 0.250 |
| Saccharin sodium | 0.500 |
Another embodiment of the invention relates to the compositions with following composition, and % represents with weight:
| Composition is described | Weight % |
| Glycerol | 30.00 |
| Urea peroxide | 15.00 |
| The polyoxyalkylene block precursor | 5.000 |
| White petrolatum | 44.50 |
| Polyvinylpyrrolidone | 10.00 |
| Flavoring agent | 0.25 |
| Saccharin sodium | 0.50 |
In another embodiment, bleaching composition has following composition:
| Composition is described | Weight % |
| 50% hydrogenperoxide steam generator | 20.000 |
| Polyoxyalkylene | 5.000 |
| White petrolatum | 74.250 |
| Polyvinylpyrrolidone | 10.000 |
| Flavoring agent | 0.250 |
| Saccharin sodium | 0.500 |
In another embodiment, bleaching composition has following composition:
| Composition is described | Weight % |
| Urea peroxide | 15.000 |
| Glycerol | 10.000 |
| White petrolatum | 50.250 |
| Polyvinylpyrrolidone | 24.000 |
| Flavoring agent | 0.250 |
| Saccharin sodium | 0.500 |
One or more during embodiment can have the following advantages.Disclosed bleaching composition can be used by professional (for example dentist) or non-DENSP (for example client).Described bleaching composition can in all sorts of ways and use easily.For example, can use described bleaching composition by alveolus, tooth protection cover or holder.Described bleaching composition also can directly be coated on the tooth, for example with brush or pen.In the embodiment that bleaching composition directly is coated with by user, do not need alveolus, tooth protection cover or holder, make the process of bleaching simpler concerning user, more comfortable.This can improve the frequency and the persistent period of using bleaching composition, also can improve effect usually.And, because compositions can discharge bleach with controlled, periodic delivery mode, be lowered so generally understand for the degree of the Sensitive disease of bleaching process itself.In addition, described bleaching composition can be realized better adhesion and better toleration to dissolution, thereby improves bleaching effect.
The particular content of one or more embodiments of the present invention is set forth in following accompanying drawings and description.Other features and advantages of the present invention can be obvious from narration, accompanying drawing and claim.
The specific embodiment
An embodiment uses the substrate of white petrolatum as compositions, and described substrate carrying bleach also keeps it in the appropriate location by tooth.Vaseline is defined as by distilling semisolid or the liquefied mixture that the paraffin-base petroleum fraction obtains.Its solid phase (mineral jelly) can be a water white or light yellow.It is mainly used in softening agent (separating medium of bakery, dehydrated fruits and vegetable), protective coating (fresh fruit and vegetable) and defoamer (beet sugar, yeast) in lightweight ointment, cosmetics, rubber composition and the food processing.Its liquid phase (paraffin oil) is used as aperient, fabric lubricant and dispersant.Solid-state version is divided into 3 grades (USP, NF and FCC) according to different specifications respectively with liquid-type.
Also can choose wantonly for following reason and to comprise polyvinylpyrrolidone (PVP).The first, because special side-chain radical on its main chain, PVP can improve the adhesion of preparation.The second, PVP is water miscible, and forms second phase in vaseline substrate, and it can control the release of peroxide from substrate.The 3rd, PVP can be used as the viscosity modifier selectivity to be added.Based on these considerations, PVP can account for about 5～30 weight %, better is about 10 weight %.
The process of the prescription shown in being produced as follows is as follows: if use solid-state peroxide reagent, then can earlier peroxide and vaseline be mixed, add following other composition, for example polyvinylpyrrolidone or glycerol then in mixture; Further mix other composition, for example flavoring agent again; If use liquid peroxide solutions, then use surfactant to prepare the uniform homogeneous blend of hydrophilic component and hydrophobic ingredient as brightening agent.
Because based on the special nature of the whitening gel or the cream of vaseline, gel directly can be used on tooth, and without alveolus, tooth protection cover or other holder.If desired, gel and base gel can be brightened system as binary and further improve whitening effect.
In preferred bleaching composition, bleaching composition has following prescription:
| Composition is described | Weight % |
| Hydrogen peroxide | 5.00 |
| Water | 5.00 |
| Polyoxyalkylene | 5.00 |
| White petrolatum | 74.250 |
| Polyvinylpyrrolidone | 10.000 |
| Flavoring agent | 0.250 |
| Saccharin sodium | 0.500 |
In another embodiment, bleaching composition has following prescription:
| Composition is described | Weight % |
| Glycerol | 30.00 |
| Urea peroxide | 15.00 |
| Polyoxyalkylene | 5.000 |
| White petrolatum | 44.50 |
| Polyvinylpyrrolidone | 10.00 |
| Flavoring agent | 0.25 |
| Saccharin sodium | 0.50 |
In another embodiment, bleaching composition has following composition:
| Composition is described | Weight % |
| 50% hydrogenperoxide steam generator | 20.000 |
| Polyoxyalkylene | 5.000 |
| White petrolatum | 74.250 |
| Polyvinylpyrrolidone | 10.000 |
| Flavoring agent | 0.250 |
| Saccharin sodium | 0.500 |
In another embodiment, bleaching composition has following composition:
| Composition is described | Weight % |
| Urea peroxide | 15.000 |
| Glycerol | 10.000 |
| White petrolatum | 50.250 |
| Polyvinylpyrrolidone | 24.000 |
| Flavoring agent | 0.250 |
| Saccharin sodium | 0.500 |
Described Lightening compositions can comprise brightening agent and viscosifier and other composition.The brightening agent or the bleach that are fit to comprise peroxide, for example hydrogen peroxide, urea peroxide or other any known chemical compound that brightens that can be used for dentistry.Peroxide solutions can have been bought various concentration, for example H on market
2O
2Can buy 35～70% concentration.Concentration in compositions can be according to the concentration of using and difference.Therefore, for the those skilled in the art in this area, the percentage by weight of the solution that is adopted can be adjusted according to the concentration of employed solution.In one embodiment, brightening agent can account for 5～30 weight %.
Except described brightening agent and viscosifier, can also contain correctives as required, for example Oleum menthae or Oleum Menthae Rotundifoliae.In addition, can also contain flavoring agent in the compositions, for example glucide or saccharin sodium.Lightening compositions can comprise any suitable correctives or its combination.The scope of the content of these flavoring agents can be from 0.06 weight % of trace or lower to about 3 weight %, and is perhaps more according to the needs that use.
Can comprise other various compositions in the embodiment.These compositions can comprise solvent, and for example water, glycerol, propylene glycol, Polyethylene Glycol or other are various is suitable as the chemical compound that solvent is applicable to the oral cavity.Described solvent can account for about 10～about 81 weight %.Described compositions also can contain solubilizing agent or emulsifying agent, for example ethoxylated castor oil.Similarly, can use any known solubilizing agent that is applicable to the oral cavity.Other solubilizing agent that is fit to comprises castor oil hydrogenated or PEG 40 castor oil hydrogenated.Solubilizing agent can account for about 1.5～about 20 weight %, for example 1.5～about 4.25 weight %.
Can also add nertralizer in the compositions, hydroxide for example is such as potassium hydroxide, sodium hydroxide or ammonium hydroxide.The another kind of nertralizer that is fit to is a triethanolamine.Described nertralizer is to help to provide suitable pH for whole compositions.Nertralizer also can be used for crosslinked thickening agent or viscosifier to form ideal gel.In one embodiment, nertralizer accounts for about 0.6～about 5.4 weight %.Suitable pH in about scope of 5.6～about 10, for example 5.6～about 7.6.
Embodiment 1
| Composition is described | Weight % |
| Hydrogen peroxide | 5.00 |
| Water | 5.00 |
| Polyoxyalkylene | 5.00 |
| White petrolatum | 74.250 |
| Polyvinylpyrrolidone | 10.000 |
| Flavoring agent | 0.250 |
| Saccharin sodium | 0.500 |
Embodiment 2
| Composition is described | Weight % |
| Hydrogen peroxide | 5.00 |
| Water | 5.00 |
| Polyoxyalkylene | 5.000 |
| White petrolatum | 83.75 |
| Polyvinylpyrrolidone | 00.000 |
| Flavoring agent | 0.250 |
| Saccharin sodium | 1.00 |
Embodiment 3
| Composition is described | Weight % |
| Hydrogen peroxide | 5.00 |
| Water | 5.00 |
| Polyoxyalkylene | 5.00 |
| White petrolatum | 73.75 |
| Polyvinylpyrrolidone | 10.00 |
| Flavoring agent | 0.25 |
| Saccharin sodium | 1.00 |
Embodiment 4
| Composition is described | Weight % |
| Glycerol | 30.00 |
| Urea peroxide | 15.00 |
| Polyoxyalkylene | 5.000 |
| White petrolatum | 44.50 |
| Polyvinylpyrrolidone | 10.00 |
| Flavoring agent | 0.25 |
| Saccharin sodium | 0.50 |
Embodiment 5
| Composition is described | Weight % |
| Glycerol | 10.00 |
| Carbamide peroxide | 15.00 |
| Ethanol | 20.00 |
| White petrolatum | 20.00 |
| Polyvinylpyrrolidone | 34.5 |
| Flavoring agent | 0.50 |
Embodiment 6
| Composition is described | Weight % |
| Hydrogen peroxide | 8.00 |
| Water | 8.00 |
| Polyoxyalkylene | 10.00 |
| White petrolatum | 64.00 |
| Polyvinylpyrrolidone | 9.00 |
| Flavoring agent | 0.50 |
| Saccharin sodium | 0.50 |
Embodiment 7
| Composition is described | Weight % |
| Hydrogen peroxide | 10.00 |
| Water | 10.00 |
| Polyoxyalkylene | 10.00 |
| White petrolatum | 60.00 |
| Polyvinylpyrrolidone | 9.00 |
| Flavoring agent | 0.50 |
| Saccharin sodium | 0.50 |
Embodiment 8
| Composition is described | Weight % |
| Hydrogen peroxide | 15.00 |
| Water | 15.00 |
| Polyoxyalkylene | 15.00 |
| White petrolatum | 45.00 |
| Polyvinylpyrrolidone | 9.00 |
| Flavoring agent | 0.50 |
| Saccharin sodium | 0.50 |
Embodiment 9
| Composition is described | Weight % |
| Hydrogen peroxide | 18.00 |
| Water | 18.00 |
| Polyoxyalkylene | 15.00 |
| White petrolatum | 39.00 |
| Polyvinylpyrrolidone | 9.00 |
| Flavoring agent | 0.50 |
| Saccharin sodium | 0.50 |
Embodiment 10
| Composition is described | Weight % |
| Hydrogen peroxide | 10.00 |
| Water | 10.00 |
| Polyoxyalkylene | 10.00 |
| White petrolatum | 30.00 |
| Polyvinylpyrrolidone | 9.00 |
| Flavoring agent | 0.50 |
| Saccharin sodium | 0.50 |
Embodiment 11
| Composition is described | Weight % |
| Hydrogen peroxide | 8.00 |
| Water | 8.00 |
| Polyoxyalkylene | 10.00 |
| Starch | 30.00 |
| White petrolatum | 34.00 |
| Polyvinylpyrrolidone | 9.00 |
| Flavoring agent | 0.50 |
| Saccharin sodium | 0.50 |
Embodiment 12
| Composition is described | Weight % |
| Hydrogen peroxide | 5.00 |
| Water | 5.00 |
| Polyoxyalkylene | 10.00 |
| Starch | 30.00 |
| White petrolatum | 40.00 |
| Polyvinylpyrrolidone | 9.00 |
| Flavoring agent | 0.50 |
| Saccharin sodium | 0.50 |
Many embodiments of the present invention have more than been disclosed.But, should understand in the spirit and scope of the invention and can do various improvement.Therefore, other embodiment also within the scope of the claims.
Claims (14)
1. compositions that is used to brighten or many teeth, described compositions comprises brightening agent and vaseline.
2. compositions as claimed in claim 1, its feature are that also described vaseline accounts for 10～90 weight % in described compositions.
3. compositions as claimed in claim 1, its feature are that also described vaseline at room temperature is a solid.
4. compositions as claimed in claim 1, its feature are that also described vaseline comprises white petrolatum.
5. compositions as claimed in claim 1, its feature are that also described brightening agent is a peroxide.
6. compositions as claimed in claim 5, its feature are that also described peroxide accounts for 35～70 weight % in described compositions.
7. compositions as claimed in claim 1 also contains viscosifier.
8. compositions as claimed in claim 7, its feature are that also described viscosifier are selected from polyvinylpyrrolidone, starch, polyoxyalkylene and their mixture.
9. compositions as claimed in claim 7, its feature are that also described viscosifier account for 5～30 weight % in described compositions.
10. compositions as claimed in claim 1 also contains solvent.
11. compositions as claimed in claim 10, its feature are that also described solvent is selected from water, glycerol, propylene glycol, Polyethylene Glycol and their mixture.
12. a compositions that is used to brighten or many teeth, described compositions comprises peroxide, solvent, polyoxyalkylene, vaseline and polyvinylpyrrolidone.
13. a method that brightens or many teeth, described method comprises:
Apply the bleaching composition of treatment effective dose on one or many teeth, described bleaching composition comprises brightening agent and vaseline; With
Described bleaching composition and one or many teeth are kept in touch, thereby this bleaching composition can brighten described one or many teeth.
14. method as claimed in claim 13, its feature also be, carries out the described process that applies by described bleaching composition being coated on described one or many teeth.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49456703P | 2003-08-13 | 2003-08-13 | |
| US60/494,567 | 2003-08-13 | ||
| US60/559,032 | 2004-04-05 | ||
| US10/914,835 | 2004-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1859896A true CN1859896A (en) | 2006-11-08 |
Family
ID=37298691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200480023167 Pending CN1859896A (en) | 2003-08-13 | 2004-08-11 | Dental bleaching |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1859896A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102625722A (en) * | 2009-08-17 | 2012-08-01 | 宝洁公司 | Oral care compositions and methods |
| CN103209738A (en) * | 2009-10-29 | 2013-07-17 | 宝洁公司 | Denture care composition |
-
2004
- 2004-08-11 CN CN 200480023167 patent/CN1859896A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102625722A (en) * | 2009-08-17 | 2012-08-01 | 宝洁公司 | Oral care compositions and methods |
| CN106176306A (en) * | 2009-08-17 | 2016-12-07 | 宝洁公司 | Oral care composition and method |
| CN103209738A (en) * | 2009-10-29 | 2013-07-17 | 宝洁公司 | Denture care composition |
| CN103209738B (en) * | 2009-10-29 | 2016-11-23 | 宝洁公司 | Denture care composition |
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