CN1857556A - Health care composition for strengthening male's immunity and its preparing method - Google Patents
Health care composition for strengthening male's immunity and its preparing method Download PDFInfo
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- CN1857556A CN1857556A CNA2006100390614A CN200610039061A CN1857556A CN 1857556 A CN1857556 A CN 1857556A CN A2006100390614 A CNA2006100390614 A CN A2006100390614A CN 200610039061 A CN200610039061 A CN 200610039061A CN 1857556 A CN1857556 A CN 1857556A
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Abstract
The present invention discloses a kind of health care composition for strengthening male's immunity and with Chinese herbal medicine materials as main ingredients. It is prepared with Chinese yam, Tuckahoe, glossy ganoderma, astragalus root, dogwood and other eight kinds of Chinese medicinal materials in certain weight proportion. It may be prepared into any one of orally taken preparations, and is used in strengthening male's immunity.
Description
Technical field
The present invention relates to a kind of Halth-care composition that strengthens male's immunity, specifically it be be food be again that some Chinese herbal medicine such as medicine and an amount of montorillonite clay are raw material, health product of making and preparation method thereof.
Background technology
Along with people change the idea of disease treatment, the emphasis of treatment has been turned to by the exogenous pathogen of direct killing and has adjusted living organism self function, thereby immunostimulant causes concern widely in the application of medical science, healthy, the especially surprise attack of infectious disease of prevent disease of expectation, be people current generally also be very normal hope.Biological purification technique of uses advanced of the present invention and high-tech powder body extra-fine grinding technology are promptly being that food is again the Chinese herbal medicine of medicine etc., add an amount of montorillonite clay and make a kind of Halth-care composition that strengthens male's immunity, the deficiency that changing nutrition can not be fully, be absorbed by the body effectively.
The present invention adds flavor according to the Dihuang Wan of key to Therapeutics of Children's Diseases, be a kind of by be food be again Rhizoma Dioscoreae, Fu Ling, the Semen Euryales of medicine, herbal raw material with Ganoderma, Ganoderma spore, the Radix Astragali, Fructus Corni, Cortex Moutan, Radix Glycyrrhizae, Rhizoma Alismatis, Radix Rehmanniae Preparata, Rhizoma Atractylodis, the Radix Aucklandiae, Fructus Mori, Radix Polygoni Multiflori, also has an amount of montorillonite clay, according to a certain weight ratio have a kind of Halth-care composition that strengthens male's immunity, effect usefulness has in fact been expanded at the classical place that has promptly kept ancient prescription again.
The present invention sets about from the many deficiency of YIN of man, and with the Radix Rehmanniae Preparata nourishing kidney-yin, beneficial marrow comes replenishing vital essence and blood, the merit of the Heshan Fructus Evodiae, Rhizoma Dioscoreae nourishing kidney the liver benefiting, spleen reinforcing; Add QI invigorating in Ganoderma and Ganoderma spore, the Radix Astragali, Rhizoma Atractylodis, the Radix Glycyrrhizae accent; Prevent the greasy fraud that stagnates that the product of nourishing produce with Cortex Moutan, Rhizoma Alismatis.The Radix Aucklandiae and tonic for assistant then mend, with the biological activity that cathartic is then let out for monarch, obey by food, allow human body improve cytophagous function from wherein obtaining active substance such as polysaccharide, reach the immunity of enhancing body self to disease.
Summary of the invention
Task of the present invention is in line with improving the policy of human body self to the immunity of disease, providing a kind of Halth-care composition that strengthens male's immunity that has, to improve people's quality of life.
Task of the present invention realizes that by following technical proposal this Halth-care composition comprises the former material of Chinese herbal medicine of following weight parts:
50～90 parts of 50～90 parts of Ganoderma spores of Rhizoma Dioscoreae 20～60 parts of volts, 10～50 portions of Ganodermas of Siberian cocklebur
120～160 parts of 10～50 parts of Radixs Astragali of 10～50 portions of Radix Glycyrrhizaes of 20～60 parts of Cortex Moutans of Fructus Corni
10～50 parts of 20～60 parts of Radix Aucklandiae of 20～60 parts of Rhizoma Atractylodis of 10～50 parts of Radix Rehmanniae Preparata of Rhizoma Alismatis
0.1～20 part of montorillonite clay
Wherein, this Halth-care composition preferably comprises the former material of Chinese herbal medicine of following weight parts:
50～90 parts of 10～50 parts of Ganoderma spores of Rhizoma Dioscoreae 20～60 parts of volts, 10～50 portions of Semen Euryaless of Siberian cocklebur
10～50 parts of 20～60 parts of Cortex Moutans of 120～160 parts of Fructus Corni of 50～90 parts of Radixs Astragali of Ganoderma
20～60 parts of 20～60 parts of Rhizoma Atractylodis of 10～50 parts of Radix Rehmanniae Preparata of 10～50 portions of Rhizoma Alismatis of Radix Glycyrrhizae
0.1～20 part of 30～70 parts of montorillonite clay of 30～70 parts of Radix Polygoni Multiflori of 10～50 portions of Fructus Moris of the Radix Aucklandiae
In the above proportioning, the weight of Halth-care composition of the present invention is calculated with the crude drug raw material, and this proportioning composition can be made into 1000 of capsule preparations.1000 in described preparation refers to the final drug preparation made, as makes 1000 doses of pharmaceutical preparatioies, 1000 in tablet, granule 1000 grams, oral liquid 1000ml etc.These are formed, and can be made into the preparation of 50～1000 taking doses, as tablet, make 1000, make 1000 of capsules, and each taking dose can be 1～a 20/or grain, can take altogether 50～1000 times.As granule, make 125 bags, each 1～2 bag, can take altogether 62.5～125 times.
The ratio of above weight proportion obtains through the science screening, when producing, can increase or reduce in corresponding ratio, is unit as large-scale production with kilogram, ton or milligram, and weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.For special population, can correspondingly adjust, adjustment amount increases or minimizing is no more than 100%, and effect is constant.
Halth-care composition of the present invention is promptly to be that food is again herbal raw materials such as medicine by what above-mentioned prescription was formed, adds an amount of montorillonite clay, through advanced biological purification technique and the processing of high-tech powder body extra-fine grinding technology, makes by the galenic pharmacy routine techniques.Described pharmaceutically active substance can obtain by extracting herbal raw material respectively, also can obtain by the co-extracted herbal raw material.
The present invention is directed to effective ingredient and impurity polysaccharide, phlegmatic temperament and tannin in the prior art and all be dissolved in the characteristics of wine, proposed to prepare the preparation method of described maintenance active substance with the wine dipper alcohol deposition method.
The invention also discloses a kind of said herbal medicine preparation of compositions method:
The first step: get each raw medicinal material by prescription;
Second step: respectively raw material Radix Rehmanniae Preparata, Fructus Corni are carried out vacuum drying, be lower than 10% to water content;
The 3rd step: the Radix Rehmanniae Preparata behind the vacuum drying, Fructus Corni raw medicinal material were added 6～10 times of weight, 56% degree Chinese liquor dipping respectively 12～36 hours, filtration residue adds 6～10 times of weight, 48～56% degree Chinese liquor again, continuous backflow 2～3 times, each 1～3 hour, merge extractive liquid, concentrated, dries, pulverized 160 mesh sieves;
The 4th step: all the other medical materials were with pulverizing 160 mesh sieves through Radix Rehmanniae Preparata, Fructus Corni residue behind 48～56% degree Chinese liquor dippings in will filling a prescription, and as containing Radix Polygoni Multiflori in the raw medicinal material, processing method is identical with the processing method of Radix Rehmanniae Preparata, Fructus Corni;
The 5th step: will soak after the montorillonite clay coarse pulverization 36～48 hours, filtration adds water and refluxes 2～3 times, each 1～3 hour, merges impregnation liquid and extracted twice liquid and concentrates, dries, pulverized 160 mesh sieves;
The 6th step: above-mentioned gained fine powder is stirred, make the required dosage form of the present composition by the conventional preparation technology of required dosage form.
Each constituent content of pure natural health-care compositions with enhancing immunity that makes as stated above is: the raw material through pulverizing has a spot of loss.
Advantage of the present invention is: according to Chinese traditional methods to keep in good health's theory, with free of contamination natural promptly be that food is again Chinese herbal medicine such as medicine, add an amount of montorillonite clay, for raw material through scientific matching.Also be the invention provides biological purification technique of a kind of uses advanced and high-tech powder body extra-fine grinding technology and carry out the processing of raw material, and keep its natural component, technological operation is simple, the capsule preparations of making (the capsule method for making promptly can be made into capsule product of the present invention routinely).Through port food mode is regulated human physiological functions, and enhancing human body immunity power improves the health of people level, optimizes people's purpose of quality of life, and method for making contains higher scientific and technological content.
Compositions of the present invention is determined usage and dosage according to the crowd's of giving and accepting situation in use, but obeys 1～4 time day every day, each 1～15 dose, as: 1～10 or sheet.
Compared with prior art: compositions provided by the invention has the health product that strengthen male's immunity.Preparations such as the ball of routine, sheet are made capsule; processing by wine and water; promptly adopt the wine dipper alcohol deposition method; remove gelatinized starch; keep effective active compositions such as alkaloid; and be the activation body of preparation of the present invention with montorillonite clay special physicochemical character, be protectant of digestive tract mucosa, improve the absorption of preparation effective ingredient.
The invention theory
It is found that herbal polysaccharide has multiple pharmacological effect such as immunomodulating, antitumor, antiviral, wherein most important when pushing away immunological enhancement.As immunostimulant or immunomodulator, Chinese herbal medicine has special advantages, and two-ways regulation function that it is remarkable and less toxicity, side effect have obtained the generally approval of world medical circle.The Radix Astragali is as typical case's representative of Chinese herbal medicine immunostimulant, and its immune enhancing function is generally acknowledged by people.
The Radix Astragali, Rhizoma Atractylodis, the Radix Aucklandiae, careless sweet in the Halth-care composition of the present invention, particularly the Radix Astragali is often joined Poria etc., with the deficiency of vital energy person of the whole body inside and outside the accent benefit human body the exterior and the interior, especially being good at invigorating the spleen and benefiting QI, for controlling deficiency of vital energy fatigue and weakness key medicine, is traditional qi-invigorating herb, can mend all void, can can hold in the palm admittedly, have effects such as QI invigorating, tonify deficiency, yang invigorating, studies show that in a large number the Radix Astragali has tangible immune enhancing function.Enoxolone (Glycyrrhetinic acid) contained in the Radix Glycyrrhizae has the effect of adrenocortical hormone sample, and various active such as antiinflammatory, antitumor are arranged.Containing a series of triterpenic acids in Ganoderma, the Ganoderma spore, is the major physiological active component of Ganoderma, Radix Polygoni Multiflori property of medicine gentleness, not dry oiliness, be equal to usefulness with Radix Rehmanniae Preparata, Fructus Corni, be used for deficiency of the liver and kindey, the vertigo, early whitening of beard and hair, can also the kidney invigorating marrow, arresting seminal emission gas, redly share double filling blood in vain.The Radix Aucklandiae is regulated the flow of vital energy and is amusing, and to dredge smooth mechanism of qi, makes the tonic tonify without causing stagnation.Also biologically active of contained pachymic acid, the triterpenes components in the Rhizoma Alismatis in the Poria in addition.The non-starchiness polysaccharide of Radix Rehmanniae, Ganoderma, the Radix Astragali, Rhizoma Dioscoreae, Rhizoma Atractylodis, Fructus Mori etc. plays an important role at the raising immunology, also has blood sugar lowering, antiinflammatory, anti-ageing many-sided effect of waiting for a long time.
Adjustment Mel, montorillonite clay strengthen biological activity, promote the invigorating the spleen and replenishing QI effect, and sliding sharp large intestine.
" name hospital opinion " speech " heart storing spirit, it is with being think of, the spleen relating to wisdom, it goes out is meaning, is that mind is thought to anticipate, fiery soil closes moral also.With the passing of time the heart hinders to manage, and spleen is hindered with the strongly fragrant of the void of anticipating, and then female disease must pass the "the philosophers," referring to the philosophers or their works, outside the Confucianists, and son can make female empty again, and institute is inevitable also." and the heart-yin is rely and supported the person, must belong to spleen, the prosperous then hemapodium of spleen, strong sub-Herba Leonuri, " institute of spleen is returned, just at this ear ".So the present invention adds flavor according to Dihuang Wan, has promptly kept the classical place of ancient prescription, expanded effect usefulness in fact again.By food clothes, allow human body improve cytophagous function from wherein obtaining active substance such as polysaccharide, reach the immunity of enhancing body self to disease, be a kind of choosing of enhancing male's immunity.
Description of drawings
Fig. 1 is the process chart of method for making of the present invention.
Activity test
The present invention is to the comparative study of immune function of mice influence
1, experiment material:
(1) compositions of the present invention
(2) BALB/C mice (male)
(3) india ink
2, experimental technique:
(1) will be by following scheme grouping, 7 every group.
A. normal saline group 0.1ml/ only
B. present composition given the test agent first group (hereinafter to be referred as the first group) 5mg/kg 0.125mg/ only
C. present composition given the test agent second group (hereinafter to be referred as the second group) 8mg/kg 0.200mg/ only
Stomach was raised mice in continuous 20 days, and the consumption of Halth-care composition of the present invention is by mice weight.
(2) the mouse T lymphocyte proliferation experiment (
3H-TdR mixes test)
Mice is put to death, and 75% is alcohol-pickled, and the aseptic spleen of getting places to fill an amount of aseptic little plate, gently spleen is torn up with tweezers, makes single cell suspension.Spleen is put 100 orders pulverize gently on the net, filter test tube.Use Hank ' s liquid to wash 3 times, each centrifugal 10min (1000r/min) abandons supernatant.Then with cell suspension in the complete culture solution of 2mL, living cell counting number (should more than 95%).It is 5 * 10 that PBL concentration is adjusted in the 1640 complete culture solutions reduction of reuse 10%FCS
6/ ml is stand-by.
Adopt conventional
3H-TdR mixes test.With mouse boosting cell suspension (5 * 10
6/ ml), add in 96 well culture plates 100 μ l/ holes, 5 * 10
5/ ml cells/well.Add ConA10 μ g/ hole respectively, matched group is supplied volume to 200 μ l with 1640 nutritional solutions.Put 5%CO
2, cultivate 72h for 37 ℃, to cultivate and finish preceding 6h, every hole adds
3The H-TdRluCi/ hole.Termination test adding in preceding 16 hours is adsorbed on cell on the glass fiber filter paper with the cell harvesting instrument, and the β scintiloscope records the cpm value and calculates stimulation index SI.
Adopt variance analysis commonly used, with per minute umber of pulse (cpm) expression propagation degree, (SI) represents with stimulation index
(4) mice carbon clearance test
Get 0.1gNa
2CO
3, adding distil water is to 100mL, and the india ink of dilution injects mice, timing immediately by every 10g body weight 0.1mL.Mice is put to death, get liver and spleen, blot the organ surface blood stains, weigh with filter paper.
Adopt variance analysis commonly used, within the specific limits, because of animal liver, spleen weight do not wait, so the K value is also different.For this reason, generally represent with gauged phagocytic index α.Represent the ability that mice carbon is cleaned up with phagocytic index.
3, date processing and experimental result:
Table 1: lymphopoiesis conversion test
| The Control meansigma methods | The ConA meansigma methods | The SI meansigma methods | The SI standard deviation | P value * | |
| The normal saline group | 1101.02 | 242446.67 | 218.46 | 36.19 | |
| The first group | 906.00 | 159844.10 | 267.12 | 63.32 | 0.0406 |
| The second group | 915.80 | 175838.51 | 309.04 | 74.97 | 0.0449 |
Annotate: the P value is experimental group: the normal saline group
Table 2: mice body weight, liver, spleen weight
| Average weight (g) | Average liver heavy (mg) | Average spleen heavy (mg) | |
| The normal saline group | 20.71 | 1010.26 | 125.55 |
| The first group | 19.87 | 1002.12 | 114.69 |
| The second group | 19.17 | 1001.61 | 114.13 |
Table 3: each organizes α value result
| The α meansigma methods | The α standard deviation | P value * | |
| The normal saline group | 4.287 | 1.625 | |
| The first group | 4.968 | 0.753 | |
| The second group | 5.508 | 1.000 |
Annotate: the P value is experimental group: the normal saline group
Above-mentioned experimental data shows:
(1) the SI value of present composition given the test agent group is significantly higher than the SI value of matched group, i.e. this experimental result positive of decidable.
(2) phagocytic index of present composition given the test agent group is higher than the phagocytic index of matched group, i.e. this experimental result positive of decidable.
So low dosage of the present invention and high dose group not only have antagonism to immunosuppressive effect, have the forward immunoregulation effect simultaneously, can improve the mice body's immunological function, and present certain dose dependent.
The selection of montorillonite clay
China finds that there are two places in the place of production of attapulgite: one in Shanxi big recessed mountain one band, relevant with cretaceous volcanic rock; One six directions in Jiangsu and Anhui two provinces boundary, a day long band, the basalt that erupts during with Miocene Epoch to the Pliocene Epoch is relevant.The geographic clay pit in Luhe can be divided into four kinds of ore type, i.e. attapulgite clay, montmorillonitic clay, hydromica attapulgite clay and dolomite attapulgite clay.Montmorillonitic clay, be by tufa stone or volcanic rock under sea water or phreatic effect, through after the secular chemical weathering, deposition forms in alkaline medium (pH=7～8.5) environment.Be a kind of aqueous layer aluminosilicate mineral, tool dispersion suspension, caking property, melt degeneration, lubricity, plasticity and good adsorption.
In the present composition and the preparation method, select montorillonite clay and Yixing, Jiangsu temmoku lakehead head water in six directions bamboo town, Nanjing for use.Select montorillonite clay to have special physicochemical character exactly, the Buddhist monk is contained multiple to people, constant or trace element that the animal health is useful, to promote to improve health.
Get Nanjing six directions bamboo town montorillonite clay, analyze with XR (f) S according to JY/T016-1996, the result is as follows for its analyzing and testing:
Measurement unit: wt%ppm
| Al 2O 3 | CaO | Fe 2O 3 | K 2O | MgO | MnO | Na 2O | P 2O 5 | SiO 2 | TiO 2 | |
| Montorillonite clay | 15.16 | 1.26 | 7.82 | 1.41 | 3.48 | 0.05 | 0.13 | 0.04 | 58.06 | 1.14 |
| Rb | Sr | y | Zr | Nb | U | Th | Pb | Mo | As | |
| Montorillonite clay | 78 | 78 | 16 | 178 | 21 | 1 | 9 | 9 | 4 | 8 |
| Zn | Ni | Sb | Ga | Co | Cr | V | Ba | Hf | Cu | |
| Montorillonite clay | 91 | 54 | 6 | 18 | 12 | 130 | 120 | 245 | 6 | 48 |
Get Yixing, Jiangsu temmoku lakehead head water, according to the GB/T5009-1996 atomic fluorescence spectrometry, the result is as follows for its analyzing and testing:
Measurement unit: mg/ml
| Al | Ba | Ca | Cd | Co | Cr | Cu | Mn | |
| Water | 0.19 | 0.027 | 49.1 | ＜0.003 | ＜0.002 | ＜0.005 | 0.002 | 0.011 |
| p | Pb | Si | Sr | Zn | Fe | Na | Ni | |
| Water | ＜0.06 | ＜0.025 | 7.04 | 0.21 | 0.03 | 0.03 | 7.82 | 0.01 |
Experimental result:
The Nanjing six directions bamboo town montorillonite clay that the present invention is selected and Yixing, Jiangsu temmoku lakehead head water contain a large amount of mineral and various trace elements, as alkalinous metal Rb and constant and trace elements zn, Cu, Cr etc.The present invention is exactly with its very active biochemical property; in compositions of the present invention, play catalyst (activation body); fully show the pharmaceutically active substance in the present composition; allow as the mode of vitamin with coenzyme; participate in the work of ferment catalytic reaction; impel all physiological function activity accelerations in the body, promote immunity with the vigor that improves human body.
The specific embodiment
(1) embodiment 1, get:
Rhizoma Dioscoreae 40g volt Siberian cocklebur 30g Ganoderma 70g Radix Rehmanniae Preparata 40g Ganoderma spore 70g
Fructus Corni 40g Cortex Moutan 30g Radix Glycyrrhizae 30g Rhizoma Alismatis 30g Radix Astragali 140g
Rhizoma Atractylodis 40g Radix Aucklandiae 30g montorillonite clay 5g
The above-mentioned raw materials medical material is processed as follows:
The first step: get each raw medicinal material by prescription;
Second step: respectively raw material Radix Rehmanniae Preparata, Fructus Corni are carried out vacuum drying, be lower than 10% to water content;
The 3rd step: the Radix Rehmanniae Preparata behind the vacuum drying, Fructus Corni raw medicinal material were added 6 times of weight, 56% degree Chinese liquor dipping respectively 12 hours, filtration residue adds 6 times of weight, 56% degree Chinese liquor again, reflux 2 times, each 3 hours, merge extractive liquid, concentrated, dries, pulverized 160 mesh sieves;
The 4th step: all the other medical materials are with pulverizing 160 mesh sieves through Radix Rehmanniae Preparata, Fructus Corni residue behind the 56% degree Chinese liquor dipping in will filling a prescription;
The 5th step: will soak after the montorillonite clay coarse pulverization 36 hours, filtration adds water and refluxes 2 times, each 3 hours, merges impregnation liquid and extracted twice liquid and concentrates, dries, pulverized 160 mesh sieves;
The 6th step: above-mentioned gained fine powder is stirred, make the capsule preparations of the present composition by capsular conventional preparation technology.
The capsule that said method makes can be eaten clothes 0.3～0.5g every day, also can be suitably every three days food clothes 0.3～0.5
G has the fatigue alleviating degree through edible experiment showed, of 25～60 years old male after edible, takes this product for a long time and has no side effect, and can regulate function of human body effectively, strengthens various immunity.
(2) embodiment 2, get:
Rhizoma Dioscoreae 20g volt Siberian cocklebur 50g Rhizoma Atractylodis 60g Ganoderma 50g Ganoderma spore 50g
Fructus Corni 60g Cortex Moutan 10g Radix Glycyrrhizae 50g Radix Rehmanniae Preparata 20g Radix Astragali 160g
Rhizoma Alismatis 10g Radix Aucklandiae 50g montorillonite clay 1g
The above-mentioned raw materials medical material is processed as follows:
The first step: get each raw medicinal material by prescription;
Second step: respectively raw material Radix Rehmanniae Preparata, Fructus Corni, Radix Polygoni Multiflori are carried out vacuum drying, be lower than 10% to water content;
The 3rd step: the Radix Rehmanniae Preparata behind the vacuum drying, Fructus Corni raw medicinal material were added 6 times of weight, 56% degree Chinese liquor dipping respectively 36 hours, filtration residue adds 6 times of weight, 56% degree Chinese liquor again, reflux 3 times, each 1 hour, merge extractive liquid, concentrated, dries, pulverized 160 mesh sieves;
The 4th step: all the other medical materials are with pulverizing 160 mesh sieves through Radix Rehmanniae Preparata, Fructus Corni residue behind the 56% degree Chinese liquor dipping in will filling a prescription;
The 5th step: will soak after the montorillonite clay coarse pulverization 48 hours, filtration adds water and refluxes 3 times, each 1 hour, merges impregnation liquid and extracted twice liquid and concentrates, dries, pulverized 160 mesh sieves;
The 6th step: above-mentioned gained fine powder is stirred, make the granule of the present composition by the conventional preparation technology of granule.
(3) embodiment 3, get:
Rhizoma Dioscoreae 60g volt Siberian cocklebur 10g Rhizoma Atractylodis 20g Ganoderma 90g Ganoderma spore 90g
Fructus Corni 20g Cortex Moutan 50g Radix Glycyrrhizae 10g Radix Rehmanniae Preparata 60g Radix Astragali 120g
Rhizoma Alismatis 50g Radix Aucklandiae 10g montorillonite clay 12g
The above-mentioned raw materials medical material is processed as follows:
The first step: get each raw medicinal material by prescription;
Second step: respectively raw material Radix Rehmanniae Preparata, Fructus Corni are carried out vacuum drying, be lower than 10% to water content;
The 3rd step: the Radix Rehmanniae Preparata behind the vacuum drying, Fructus Corni raw medicinal material were added 8 times of weight, 56% degree Chinese liquor dipping respectively 24 hours, filtration residue adds 8 times of weight, 56% degree Chinese liquor again, reflux 2 times, each 2 hours, merge extractive liquid, concentrated, dries, pulverized 160 mesh sieves;
The 4th step: all the other medical materials are with pulverizing 160 mesh sieves through Radix Rehmanniae Preparata, Fructus Corni residue behind the 56% degree Chinese liquor dipping in will filling a prescription;
The 5th step: will soak after the montorillonite clay coarse pulverization 36 hours, filtration adds water and refluxes 2 times, each 2 hours, merges impregnation liquid and extracted twice liquid and concentrates, dries, pulverized 160 mesh sieves;
The 6th step: above-mentioned gained fine powder is stirred, make the pill of the present composition by the conventional preparation technology of pill.
(4) embodiment 4, get:
Rhizoma Dioscoreae 40g volt Siberian cocklebur 30g Semen Euryales 30g Ganoderma 70g Ganoderma spore 70g
Radix Glycyrrhizae 30g Rhizoma Alismatis 30g Fructus Corni 40g Cortex Moutan 30g Radix Astragali 140g
Radix Rehmanniae Preparata 40g Rhizoma Atractylodis 40g Radix Aucklandiae 40g Fructus Mori 50g Radix Polygoni Multiflori 50g
Montorillonite clay 5g
The above-mentioned raw materials medical material is processed as follows:
The first step: get each raw medicinal material by prescription;
Second step: respectively raw material Radix Rehmanniae Preparata, Fructus Corni, Radix Polygoni Multiflori are carried out vacuum drying, be lower than 10% to water content;
The 3rd step: the Radix Rehmanniae Preparata behind the vacuum drying, Fructus Corni, Radix Polygoni Multiflori raw medicinal material were added 8 times of weight, 56% degree Chinese liquor dipping respectively 24 hours, filtration residue adds 8 times of weight, 56% degree Chinese liquor again, reflux 2 times, each 2 hours, merge extractive liquid, concentrated, dries, pulverized 160 mesh sieves;
The 4th step: all the other medical materials are with pulverizing 160 mesh sieves through Radix Rehmanniae Preparata, Fructus Corni, Radix Polygoni Multiflori residue behind the 56% degree Chinese liquor dipping in will filling a prescription;
The 5th step: will soak after the montorillonite clay coarse pulverization 36 hours, filtration adds water and refluxes 2 times, each 2 hours, merges impregnation liquid and extracted twice liquid and concentrates, dries, pulverized 160 mesh sieves;
The 6th step: above-mentioned gained fine powder is stirred, make the capsule preparations of the present composition by the conventional preparation technology of capsule.
(5) embodiment 5, get:
Rhizoma Dioscoreae 20g volt Siberian cocklebur 40g Semen Euryales 10g Ganoderma 90g Ganoderma spore 90g
Radix Glycyrrhizae 10g Rhizoma Alismatis 50g Fructus Corni 60g Cortex Moutan 10g Radix Astragali 120g
Radix Aucklandiae 40g Fructus Mori 30g Radix Rehmanniae Preparata 20g Rhizoma Atractylodis 60g Radix Polygoni Multiflori 70g
Montorillonite clay 10g
The above-mentioned raw materials medical material is processed as follows:
The first step: get each raw medicinal material by prescription;
Second step: respectively raw material Radix Rehmanniae Preparata, Fructus Corni, Radix Polygoni Multiflori are carried out vacuum drying, be lower than 10% to water content;
The 3rd step: the Radix Rehmanniae Preparata behind the vacuum drying, Fructus Corni, Radix Polygoni Multiflori raw medicinal material were added 8 times of weight, 56% degree Chinese liquor dipping respectively 24 hours, filtration residue adds 8 times of weight, 56% degree Chinese liquor again, reflux 2 times, each 2 hours, merge extractive liquid, concentrated, dries, pulverized 160 mesh sieves;
The 4th step: all the other medical materials are with pulverizing 160 mesh sieves through Radix Rehmanniae Preparata, Fructus Corni, Radix Polygoni Multiflori residue behind the 56% degree Chinese liquor dipping in will filling a prescription;
The 5th step: will soak after the montorillonite clay coarse pulverization 36 hours, filtration adds water and refluxes 2 times, each 2 hours, merges impregnation liquid and extracted twice liquid and concentrates, dries, pulverized 160 mesh sieves;
The 6th step: above-mentioned gained fine powder is stirred, make the powder of the present composition by the conventional preparation technology of powder.
(6) embodiment 6, get:
Rhizoma Dioscoreae 60g volt Siberian cocklebur 20g Semen Euryales 50g Ganoderma 50g Ganoderma spore 50g
Radix Glycyrrhizae 50g Rhizoma Alismatis 10g Fructus Corni 20g Cortex Moutan 40g Radix Astragali 160g
Radix Rehmanniae Preparata 60g Rhizoma Atractylodis 20g Radix Aucklandiae 20g Fructus Mori 70g Radix Polygoni Multiflori 30g
Montorillonite clay 15g
The above-mentioned raw materials medical material is processed as follows:
The first step: get each raw medicinal material by prescription;
Second step: respectively raw material Radix Rehmanniae Preparata, Fructus Corni, Radix Polygoni Multiflori are carried out vacuum drying, be lower than 10% to water content;
The 3rd step: the Radix Rehmanniae Preparata behind the vacuum drying, Fructus Corni, Radix Polygoni Multiflori raw medicinal material were added 8 times of weight, 56% degree Chinese liquor dipping respectively 24 hours, filtration residue adds 8 times of weight, 56% degree Chinese liquor again, reflux 2 times, each 2 hours, merge extractive liquid, concentrated, dries, pulverized 160 mesh sieves;
The 4th step: all the other medical materials are with pulverizing 160 mesh sieves through Radix Rehmanniae Preparata, Fructus Corni, Radix Polygoni Multiflori residue behind the 56% degree Chinese liquor dipping in will filling a prescription;
The 5th step: will soak after the montorillonite clay coarse pulverization 36 hours, filtration adds water and refluxes 2 times, each 2 hours, merges impregnation liquid and extracted twice liquid and concentrates, dries, pulverized 160 mesh sieves;
The 6th step: above-mentioned gained fine powder is stirred, make the tablet of the present composition by the conventional preparation technology of tablet.
Claims (5)
1, a kind of Halth-care composition that strengthens male's immunity, form by following bulk drugs:
50～90 parts of 50～90 parts of Ganoderma spores of Rhizoma Dioscoreae 20～60 parts of volts, 10～50 portions of Ganodermas of Siberian cocklebur
10～50 parts in 10～50 portions of Radix Glycyrrhizaes of 20～60 parts of Cortex Moutans of 120～160 parts of Fructus Corni of the Radix Astragali
10～50 parts of 20～60 parts of Radix Aucklandiae of 20～60 parts of Rhizoma Atractylodis of 10～50 parts of Radix Rehmanniae Preparata of Rhizoma Alismatis
0.1～20 part of montorillonite clay.
2, Halth-care composition according to claim 1, form by following bulk drugs:
50～90 parts of 10～50 parts of Ganoderma spores of Rhizoma Dioscoreae 20～60 parts of volts, 10～50 portions of Semen Euryaless of Siberian cocklebur
10～50 parts of 20～60 parts of Cortex Moutans of 120～160 parts of Fructus Corni of 50～90 parts of Radixs Astragali of Ganoderma
20～60 parts of 20～60 parts of Rhizoma Atractylodis of 10～50 parts of Radix Rehmanniae Preparata of 10～50 portions of Rhizoma Alismatis of Radix Glycyrrhizae
0.1～20 part of 30～70 parts of montorillonite clay of 30～70 parts of Radix Polygoni Multiflori of 10～50 portions of Fructus Moris of the Radix Aucklandiae
3,, it is characterized in that its dosage form is the dosage form that allows on any pharmaceutics according to the Halth-care composition of claim 1.
4,, it is characterized in that described dosage form is capsule, tablet, granule, pill, powder, sublimed preparation, drop pill, oral liquid, syrup, unguentum or cream according to the Halth-care composition of claim 3.
5, the preparation method of claim 1 or 2 described Halth-care compositions is characterized in that this method comprises the steps:
The first step: get each raw medicinal material by proportioning;
Second step: respectively raw material Radix Rehmanniae Preparata, Fructus Corni are carried out vacuum drying, be lower than 10% to water content;
The 3rd step: the Radix Rehmanniae Preparata behind the vacuum drying, Fructus Corni raw medicinal material were added 6～10 times of weight, 48～56% degree Chinese liquor dippings respectively 12～36 hours, filtration residue adds 6～10 times of weight, 48～56% degree Chinese liquor again, reflux 2～3 times, each 1～3 hour, merge extractive liquid, concentrated, dries, pulverized 160 mesh sieves;
The 4th step: with pulverizing 160 mesh sieves through Radix Rehmanniae Preparata, Fructus Corni residue behind 48～56% degree Chinese liquor dippings, as containing Radix Polygoni Multiflori in the raw medicinal material, processing method is identical with the processing method of Radix Rehmanniae Preparata, Fructus Corni with all the other medical materials in the proportioning;
The 5th step: will soak after the montorillonite clay coarse pulverization 36～48 hours, filtration adds water and refluxes 2～3 times, each 1～3 hour, merges impregnation liquid and extracted twice liquid and concentrates, dries, pulverized 160 mesh sieves;
The 6th step: above-mentioned gained fine powder is stirred, make required dosage form by the conventional preparation technology of required dosage form.
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| CNB2006100390614A CN100400072C (en) | 2006-03-24 | 2006-03-24 | Health care composition for strengthening male's immunity and its preparing method |
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| CNB2006100390614A CN100400072C (en) | 2006-03-24 | 2006-03-24 | Health care composition for strengthening male's immunity and its preparing method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102919848A (en) * | 2012-11-26 | 2013-02-13 | 李成仁 | Oil mixture capable of improving immunity |
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| CN1238205A (en) * | 1999-02-28 | 1999-12-15 | 王跃进 | Biogene leading composition |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102919848A (en) * | 2012-11-26 | 2013-02-13 | 李成仁 | Oil mixture capable of improving immunity |
| WO2014079395A1 (en) * | 2012-11-26 | 2014-05-30 | Li Chengren | Oil mixture capable of improving immunity |
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| Publication number | Publication date |
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| CN100400072C (en) | 2008-07-09 |
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